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Romandolide
Romandolide, an intriguing compound with the potential to attenuate inflammatory responses, displays promising therapeutic implications for conditions like rheumatoid arthritis and inflammatory bowel disease. Its mechanism of action remains under investigation, warranting further exploration into its pharmacological properties. Alternative Names: Acetic acid, 2-(1-oxopropoxy)-, 1-(3,3-dimethylcyclohexyl)ethyl ester; musk methyl propionate; 2-[1-(3,3-Dimethylcyclohexyl)ethoxy]-2-oxoethyl propionate; 1-(3,3-Dimethylcyclohexyl)ethyl 2-(1-oxopropoxy)acetate; Acetic acid, (1-oxopropoxy)-, 1-(3,3-dimethylcyclohexyl)ethyl ester; 1-(3,3-Dimethylcyclohexyl)ethyl 2-(1-oxopropoxy)acetate. Grades: ≥95%. CAS No. 236391-76-7. Molecular formula: C15H26O4. Mole weight: 270.36.
Roma PWA 40
Roma PWA 40. Grades: 95%. CAS No. 9069-80-1.
Romifidine hydrochloride
Romifidine is an α2 agonist used as a sedative and analgesic in horses. Alternative Names: N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride; STH 2130Cl; Sedivet. CAS No. 65896-14-2. Molecular formula: C9H10BrClFN3. Mole weight: 294.55.
Romiplostim
Romiplostim is fusion protein thrombopoietin (TPO) peptide analog that regulates the number of platelets. Romiplostim has been used in the treatment of thrombocytopenia associated with chronic immune thrombocytopenia (ITP). CAS No. 267639-76-9. Molecular formula: C2634H4086N722O790S18. Mole weight: 59000.0 Da.
Romosozumab
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Romosozumab binds to and inhibits sclerostin, promoting the activation of the Wnt/β-catenin pathway that normally stimulates osteoblasts. Alternative Names: Evenity. CAS No. 909395-70-6.
Roniciclib
Roniciclib, also known as BAY 1000394, is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. BAY1000394 selectively binds to and inhibits the activity of CDK1 / Cyclin B, CDK2 / Cyclin E, CDK4 / Cyclin D1, and CDK9 / Cyclin T1, serine / threonine kinases that play key roles in the regulation of the cell cycle progression and cellular proliferation. Alternative Names: BAY10-00394; BAY1000394; BAY 1000394; NSC774911; (2R,3R)-3-{[2-{[4-(S-Cyclopropylsulfonimidoyl)phenyl]amino}-5-(trifluoromethyl)-4-pyrimidinyl]oxy}-2-butanol; 2-Butanol, 3-[[2-[[4-(S-cyclopropylsulfonimidoyl)phenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]oxy]-, (2R,3R)-. Grades: ≥98%. CAS No. 1223498-69-8. Molecular formula: C18H21F3N4O3S. Mole weight: 430.44.
Ronidazole
Ronidazole is an antiprotozoal agent. Uses: Antiprotozoal agents. Alternative Names: 1-Methyl-5-nitro-1H-imidazole-2-methanol 2-Carbamate; (1-Methyl-5-nitroimidazol-2-yl)methyl Carbamate; 1-Methyl-2-carbamoyloxymethyl-5 -nitroimidazole; Dugro; MCMN; Ridzol; Ridzol P; Ridzole; Ronida BT. Grades: >98%. CAS No. 7681-76-7. Molecular formula: C6H8N4O4. Mole weight: 200.15.
Ronopterin
Ronopterin is a potent Nitric oxide synthase inhibitor used as a neuroprotectant. Alternative Names: VAS-203; VAS 203; VAS203; Ronopterin; (1R,2S)-1-[(6R)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol; 4-aminotetrahydrobiopterin. Grades: >98%. CAS No. 206885-38-3. Molecular formula: C9H16N6O2. Mole weight: 240.27.
Rosa Canina Extract
Rosa canina extract, derived from the wild rose (often known as rose hip), is rich in vitamin C, flavonoids, carotenoids, and essential fatty acids, contributing to its numerous health benefits. The extract is primarily known for its anti-inflammatory, antioxidant, and immune-boosting properties. Rosa canina extract is commonly used to boost the immune system, particularly during cold and flu seasons, due to its high vitamin C content. It also has joint health benefits, as it helps reduce inflammation and pain in conditions like arthritis. The extract's antioxidant properties help protect cells from oxidative stress and may contribute to skin health by promoting collagen synthesis, reducing the appearance of wrinkles, and supporting overall skin elasticity. Additionally, rose hip extract has been shown to improve digestive health and may aid in weight management by promoting healthy metabolism. Rosa canina extract is commonly found in immune support supplements, joint health formulas, and skincare products. Uses: Anti-arthritic agents, anti-oxidant agents. Alternative Names: Rosehip Exrtact; Rose heps Exrtact; Burr rose Exrtact; Camellia rose Exrtact; Chestnut rose Exrtact; French rose Exrtact; Heps Exrtact; Hip berry Exrtact; Virginia rose Exrtact; Rosa canina ext.; Rose, Rosa canina, ext. CAS No. 84696-47-9.
Rose Bengal
Rose Bengal is a photosensitizer and dye used in eye drops for diagnosis. It also acts as a VGlut and vesicular monoamine transporter (VMAT) inhibitor. Alternative Names: Rose bengal sodium; Rose bengal disodium salt; 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one disodium salt. Grades: ≥98% by HPLC. CAS No. 632-69-9. Molecular formula: C20H2Cl4I4Na2O5. Mole weight: 1017.64.
Rose hip oil
Rose hip oil. Alternative Names: Rosehips(Rosacanina)oil; ROSE(ROSAMULTIFLORA)OIL; Rose Hips Seed Oil; Rose Hip Oil. Grades: 95%. CAS No. 84603-93-0.
Rosemary, Rosmarinus officinalis latifolius, ext.
Rosemary, Rosmarinus officinalis latifolius, ext. CAS No. 93348-56-2.
Rose oil
Rose Oil is commonly used in cosmetics and aromatherapy. It is widely used as a flavoring agent in beauty, body, food, tobacco, perfume and cosmetics. Rose essential oil can prevent infectious diseases, treat skin and regulate endocrine. CAS No. 8007-01-0. Molecular formula: H14. Mole weight: 14.11.
Rosin
Rosin is a complex combination derived from wood, especially pine wood. Composed primarily of resin acids and modified resin acids such as dimers and decarboxylated resin acids. Includes rosin stabilized by catalytic disproportionation. Rosin is commonly used as a flux in soldering and in making paints and varnishes. Alternative Names: Abieta DR 836A; AL 104 (rosin); Bandis G 100; Bandis T 100H; Chinese Rosin WW; Chinese Rosin X; Colophane; Colophony; D 101 (rosin); Disproportionated rosin; EM 3 (rosin); Foralyn 5020; Gum rosin; Gum Rosin CG-WW; Harsize NES 405; HRS 50 (rosin); Inktac 103; Inktac TX; Kenomic A 35; Liquid rosin; Naval stores, rosin; Optika; P 90 (rosin); Pine resin; Resin 95; Resins, pine; Resins, rosin; SW 50 (rosin); Tyreon 160; Unitol HYR; Wanan WA; Wood rosin; Yellow resin. CAS No. 8050-9-7. Molecular formula: C15H20O6. Mole weight: 296.32.
Rosin Amine D
A commercial mixture containing dehydroabietlyamine (Hercules). Grades: 95%. CAS No. 12698-87-2.
Rosin, fumarated, polymer with pentaerythritol
Rosin, fumarated, polymer with pentaerythritol. CAS No. 65997-11-7.
Rosmanol
Rosmanol is a novel antioxidant found in Rosemary. Alternative Names: UNII-F25TV383OC; (4bR,8aS,9S,10S)-3,4,10-Trihydroxy-2-isopropyl-8,8-dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epoxymethano)phenanthren-12-one; AK101906; SCHEMBL459610. CAS No. 80225-53-2. Molecular formula: C20H26O5. Mole weight: 346.423.
Rosmarinus Officinalis Leaf Extract
Rosmarinus Officinalis Leaf Extract, derived from the leaves of the rosemary plant, is well-known for its antioxidant, anti-inflammatory, antimicrobial, and cognitive-enhancing properties. The active compounds in the extract include rosmarinic acid, carnosic acid, carnosol, and flavonoids, which contribute to its health benefits. Rosmarinus Officinalis Leaf Extract is widely used for its antioxidant effects, helping protect cells from oxidative stress and supporting overall brain health by improving memory, focus, and cognitive function. It is also used to reduce inflammation, making it beneficial for treating arthritis, joint pain, and muscle soreness. Additionally, rosemary extract is known for its antimicrobial properties, helping to combat infections and support skin health by reducing acne and skin irritation. It also has digestive benefits, promoting healthy digestion and alleviating symptoms of indigestion. Rosmarinus Officinalis Leaf Extract is commonly found in herbal supplements, skincare products, and cognitive support formulas. Uses: Anti-oxidant agents, oral care agents. Alternative Names: Rosemary extract; Rosmarinus Officinalis extract; Rosemary, ext.; extract of rosemary; Hydroalcoholic extract of rosemary; Natural rosemary extract; Rosemary dry extract; Rosemary extract compounds; Rosemary extracts; Rosemary exts.; Rosemary leaf extract; Rosemary leaf extracts; Supercritical extract of
Rosuvastatin EP Impurity A
Rosuvastatin EP Impurity A is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: (3R,5S,6E)-7-[2-(2,N-Dimethyl-2-hydroxypropane-1-sulfonamido)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl](methyl)amino]-6-(1-methylethyl)-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-hydroxy-N,2-dimethylpropyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid; S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid; Rosuvastatin Calcium EP Impurity A. Grades: ≥95%. CAS No. 1715120-13-0. Molecular formula: C25H34FN3O7S. Mole weight: 539.62.
Rosuvastatin EP Impurity A Calcium Salt
Rosuvastatin EP Impurity A Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-hydroxy-N,2-dimethylpropyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate Calcium Salt; S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin Calcium Salt; (3R,5S,6E)-7-[2-(2,N-Dimethyl-2-hydroxypropane-1-sulfonamido)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid calcium salt; Calcium (3R,5S,E)-7-{4-(4-fluorophenyl)-2-[(2-hydroxy-N,2-dimethylpropyl)sulfonamide]-6-isopropylpyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate salt (1:2); USP Rosuvastatin Related Compound A; Rosuvastatin Related Compound A; Rosuvastatin USP Related Compound A. Grades: ≥95%. CAS No. 1714147-47-3. Molecular formula: C25H33FN3O7S.1/2Ca. Mole weight: 558.65.
Rosuvastatin EP Impurity C
Rosuvastatin EP Impurity C is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: (3R,6E)-7-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3-hydroxy-5-oxohept-6-enoic acid; Rosuvastatin Calcium EP Impurity C; (3R,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3-hydroxy-5-oxohept-6-enoic acid; 5-Oxo Rosuvastatin; Rosuvastatin Impurity C; (3R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-6-heptenoic Acid; 3-Hydroxy-5-keto Rosuvastatin; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, (3R,6E)-; (R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid; 5-Oxorosuvastatin; Rosuvastatin ketone [USP]; NSC-800037. Grades: 95%. CAS No. 1422619-13-3. Molecular formula: C22H26FN3O6S. Mole weight: 479.52.
Rosuvastatin EP Impurity C Calcium Salt
Rosuvastatin EP Impurity C Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, calcium salt (2:1), (3R,6E)-; Calcium (3R,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-6-heptenoate (1:2); (3R,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic acid calcium salt; (R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid calcium salt. Grades: ≥95%. CAS No. 1422514-05-3. Molecular formula: C22H26FN3O6S.1/2Ca. Mole weight: 997.11.
Rosuvastatin EP Impurity D
Rosuvastatin EP Impurity D is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Rosuvastatin Calcium EP Impurity D; N-(4-(4-Fluorophenyl)-5-((E)-2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(1E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethen-1-yl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methylethyl)-pyrimidin-2-yl]-N-methylmethanesulfonamide; Rosuvastatin Lactone; Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-; N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide; Rosuvastatin-5S-lactone. Grades: ≥95%. CAS No. 503610-43-3. Molecular formula: C22H26FN3O5S. Mole weight: 463.53.
Rosuvastatin EP Impurity E
Rosuvastatin EP Impurity E is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Rosuvastatin Calcium EP Impurity E; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[(2ξ)-2-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-2-hydroxy-N-methylethane-1-sulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[[2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl]-2-hydroxyethyl]sulfonyl](methyl)-amino]-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-2-hydroxy-N-methylethyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[[2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-2-hydroxyethyl]sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[[2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-2-hydroxyethyl]sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid. Grades: ≥95%. CAS No. 2226413-61-0. Molecular formula: C38H46F2N6O9S2
Rosuvastatin EP Impurity FP-B (6R-isomer) calcium salt
Rosuvastatin EP Impurity FP-B (6R-isomer) calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: (3R,5S)-5-((R)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate calcium(II) salt; Benzo[h]quinazoline-6-pentanoic acid, 8-fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, calcium salt (2:1), (βR,δS,6R)-; (βR,δS,6R)-8-Fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]benzo[h]quinazoline-6-pentanoic acid calcium salt; Rosuvastatin Dihydrobenzoquinazoline (6R)-Isomer calcium salt. Grades: ≥95%. CAS No. 854898-49-0. Molecular formula: C22H27FN3O6S.1/2Ca. Mole weight: 500.57.
Rosuvastatin EP Impurity FP-B (6S-isomer) calcium salt
Rosuvastatin EP Impurity FP-B (6S-isomer) calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Benzo[h]quinazoline-6-pentanoic acid, 8-fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, calcium salt (2:1), (βR,δS,6S)-; (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate calcium(II) salt; (βR,δS,6S)-8-Fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]benzo[h]quinazoline-6-pentanoic acid calcium salt; Rosuvastatin Dihydrobenzoquinazoline (6S)-Isomer calcium salt. Grades: ≥95%. CAS No. 854898-50-3. Molecular formula: C22H28FN3O6S.1/2Ca. Mole weight: 500.57.
Rosuvastatin EP Impurity G calcium salt
Rosuvastatin EP Impurity G calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Calcium (3S,5R,E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate salt (1:2); 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3S,5R,6E)-; Rosuvastatin Enantiomer; (3S,5R,6E)-Rosuvastatin Calcium Salt; Calcium (3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; (3S,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt (2:1). Grades: ≥95%. CAS No. 2414245-11-5. Molecular formula: C22H28FN3O6S.1/2Ca. Mole weight: 500.57.
Rosuvastatin EP Impurity K
Rosuvastatin EP Impurity K is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: (2Z,5S,6E)-7-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-5-hydroxyhepta-2,6-dienoic acid; Rosuvastatin EP Impurity K (2Z-Isomer); (S,2Z,6E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhepta-2,6-dienoic acid; 2,3-Dehydro-3-Deshydroxy-(2Z)-Rosuvastatin; 2,6-Heptadienoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-, (2Z,5S,6E)-; (2Z,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-2,6-heptadienoic acid; 2,3-Anhydro rosuvastatin. Grades: ≥95%. CAS No. 1422954-12-8. Molecular formula: C22H26FN3O5S. Mole weight: 463.52.
Rosuvastatin EP Impurity L
Rosuvastatin EP Impurity L is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Rosuvastatin Calcium EP Impurity L; (3ξ,5ξ)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyheptanoic acid; (3ξ,5ξ)-6,7-Dihydro Rosuvastatin; 5-Pyrimidineheptanoic acid, 4-(4-fluorophenyl)-β,δ-dihydroxy-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-; 4-(4-Fluorophenyl)-β,δ-dihydroxy-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidineheptanoic acid. Grades: ≥95%. CAS No. 1024064-70-7. Molecular formula: C22H30FN3O6S. Mole weight: 483.56.
Rosuvastatin EP Impurity M
Rosuvastatin EP Impurity M is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Rosuvastatin Calcium EP Impurity M; (3R,5S,6E)-7-[2-(N-methylmethanesulfonamido)-4-phenyl-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-3,5-dihydroxy-7-(4-isopropyl-2-(N-methylmethylsulfonamido)-6-phenylpyrimidin-5-yl)hept-6-enoic acid; 6-Heptenoic acid, 3,5-dihydroxy-7-[4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-6-phenyl-5-pyrimidinyl]-, (3R,5S,6E)-; (3R,5S,6E)-3,5-Dihydroxy-7-[4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-6-phenyl-5-pyrimidinyl]-6-heptenoic acid; Desfluoro Rosuvastatin. Grades: ≥95%. CAS No. 847849-66-5. Molecular formula: C22H29N3O6S. Mole weight: 463.55.
Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Alternative Names: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester. Grades: > 95%. CAS No. 147118-40-9. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
Rotenone is a botanical insecticide that occurs naturally in seeds and stems of several plants. Rotenone is a mitochondrial electron transport inhibitor, inhibiting NADH/DB oxidoreductase and NADH oxidase with IC50 values of 28.8 and 5.1 nM, respectively. Alternative Names: Rotenone; NSC 26258; NSC-26258; NSC26258; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: ≥95% by HPLC. CAS No. 83-79-4. Molecular formula: C23H22O6. Mole weight: 394.42.
Rotigotine HCl
The hydrochloride salt form of rac-Rotigotine, a mixture of S- and R-Rotigotine, is an effective and highly selective D-2 receptor agonist which could be used in the treatment of the Parkinson's disease. Ki: 0.69 nM. Uses: The hydrochloride salt form of rac-rotigotine is an effective and highly selective d-2 receptor agonist which could be used in the treatment of the parkinson's disease. Alternative Names: 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride. Grades: 95%. CAS No. 102120-99-0. Molecular formula: C19H26ClNOS. Mole weight: 351.93.
Rottlerin
Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Uses: Enzyme inhibitors. Alternative Names: 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone. Grades: ≥98% (HPLC). CAS No. 82-08-6. Molecular formula: C30H28O8. Mole weight: 516.55.
Rovalpituzumab
Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of ADC Rovalpituzumab Tesirine, which has been investigated for the treatment of SCLC. CAS No. 1613313-01-1.
Roxatidine hydrochloride
An impurity of potent Rotundine. Rotundine is a selective dopamine D1 receptor antagonist. Alternative Names: Acetamide, 2-hydroxy-N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-, monohydrochloride. CAS No. 97900-88-4. Molecular formula: C17H27ClN2O3. Mole weight: 342.86.
RP-3500
RP-3500 is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. RP-3500 shows 30-fold selectivity for ATR over mTOR (IC50 = 120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Antitumor activity. Alternative Names: ATR inhibitor 4. CAS No. 2417489-10-0. Molecular formula: C21H26N6O3. Mole weight: 410.47.
RP-6530
RP-6530, a purine derivative, has been found to be a PI3Kδ/γ inhibitor that could exhibit cytotoxicity in some lymphoma primary cells so that is significant in antineoplastic researches. It has already completed a Phase I trial for Haematological malignancies. Uses: Phosphoinositide-3 kinase inhibitors. Alternative Names: RP-6530; RP6530; RP 6530; Tenalisib; (S)-2-(1-((7H-purin-6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one. Grades: 98%. CAS No. 1639417-53-0. Molecular formula: C23H18FN5O2. Mole weight: 415.43.
Rp-8-AHA-cAMPS-Agarose
Rp-8-AHA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
RPL-554
RPL 554 is a potent and selective PDE3/4 inhibitor for respiratory diseases, particularly in patients with asthma. Uses: A potent and selective pde3/4 inhibitor. Alternative Names: [2-[6,7-Dihydro-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl]ethyl]-urea;UNII-3E3D8T1GIX;RPL-554; RPL-554; RPL-554; LS-193,855; LS 193,855; LS 193,855; LS193855; LS193855; LS-193855. Grades: ≥96%. CAS No. 298680-25-8. Molecular formula: C26H31N5O4. Mole weight: 477.56.
R-Pralatrexate
The R isometric form of Pralatrexate which is a folate analog used to treat relapsed or refractory peripheral T-cell lymphoma. Alternative Names: Pralatrexate, (R)-; (R)-pralatrexate; 1320211-70-8; UNII-9CY33O2XLX; 9CY33O2XLX; L-Glutamic acid, N-(4-((1R)-1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-; 1320211-70-8 (R-isomer); (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid; SCHEMBL1889869; DTXSID001031315; AKOS040747299; PD132342; HY-117791; CS-0068078; Q27272363; (2S)-2-[[4-[(2R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid. Grades: > 95%. CAS No. 1320211-70-8. Molecular formula: C23H23N7O5. Mole weight: 477.48.
R-Rivaroxaban
5-R-Rivaroxaban is the R-isomer of Rivaroxaban, which is a novel, oral, direct Factor Xa (FXa) inhibitor. It is useful for antithrombotic agent and is a promising drug for atrial fibrillation, venous thromboembolism or thromboembolic disorders in clinic. Uses: 5-r-rivaroxaban is useful for antithrombotic agent and is a promising drug for atrial fibrillation, venous thromboembolism or thromboembolic disorders in clinic. Alternative Names: (R)-5-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide; 5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide; BAY 59-7939; R-Rivaroxaban; ent-Rivaroxaban; Rivaroxaban R-Enantiomer; Rivaroxaban EP Impurity A. Grades: >98%. CAS No. 865479-71-6. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
(R,R,R)-(+)-Xyl-SKP
(R,R,R)-(+)-Xyl-SKP (CAS# 1429939-35-4 ) is a useful research chemical. Alternative Names: (+)-1,13-Bis[di(3,5-diMethylphenyl)phosphino]-(5aR,8aR,14aR)-5a,6,7,8,8a,9-hexahydro-5H-[1]benzopyrano[3,2-d]xanthene; 1,1'-[(5aR,8aR,14aR)-5a,6,7,8,8a,9-Hexahydro-5H-[1]benzopyrano[3,2-d]xanthene-1,13-diyl]bis[1,1-di(3,5-dimethylphenyl)phosphine]; [20-Bis(3,5-dimethylphenyl)phosphanyl-2,22-dioxapentacyclo[12.8.0.01,10.03,8.016,21]docosa-3(8),4,6,16(21),17,19-hexaen-4-yl]-bis(3,5-dimethylphenyl)phosphane. CAS No. 1429939-35-4. Molecular formula: C52H54O2P2. Mole weight: 772.93.
The R-enantiomer of Thalidomide which interacts directly with the protein cereblon (CRBN; IC50=8.5 nM), a ubiquitously-expressed E3 ligase. Alternative Names: (R)-Thalidomide; (+)-Thalidomide; (R)-(+)-thalidomide; D-Thalidomide; 2614-06-4; R-(+)-Thalidomide; Thalidomide, (R)-; QN61H68KLK; 2-[(3R)-2,6-dioxopiperidin-3-yl]isoindole-1,3-dione; CHEBI:61917; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)-; (R)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)-; 2-[(3R)-2,6-dioxopiperidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione; 2-[(3R)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione; 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione; NSC 91729; NSC-91729; (R)-(D)-Thalidomide. Grades: > 95%. CAS No. 2614-6-4. Molecular formula: C13H10N2O4. Mole weight: 258.24.
Rubicene
Rubicene (CAS# 197-61-5 ) is a useful research chemical. Alternative Names: Benzo(A)indeno(1,2,3-HI)aceanthrylene. Grades: 95 %. CAS No. 197-61-5. Molecular formula: C26H14. Mole weight: 326.39.
Rubidium carbonate, Rb2CO3, is a convenient compound of rubidium; it is stable, not particularly reactive, and readily soluble in water, and is the form in which rubidium is usually sold. Alternative Names: Carbonicacid,dirubidiumsalt; dirubidiumcarbonate; dirubidiummonocarbonate; RUBIDIUM CARBONATE; Rubidium carbonate, 99.8% metals basis; RUBIDIUM CARBONATE (99%-RB); RUBIDIUM CARBONATE (99.8+%-RB); Rubidiumcarbonate; 99.99%. Grades: 99%. CAS No. 584-09-8. Molecular formula: Rb2CO3. Mole weight: 230.94.
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Alternative Names: Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, [R-(E)]-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-, (9aR)- (9CI). Grades: > 95%. CAS No. 514-66-9. Molecular formula: C21H23NO4. Mole weight: 353.42.
Rucaparib
Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Alternative Names: 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd)indol-6-one; Rucaparib free base, AG-14447; AG 14447; AG14447; Rubraca. Grades: >98%. CAS No. 283173-50-2. Molecular formula: C19H18FN3O. Mole weight: 323.36.
RuCl[(S,S)-Tsdpen](mesitylene)
RuCl[(S,S)-Tsdpen](mesitylene). CAS No. 174813-81-1. Molecular formula: C30H33ClN2O2RuS. Mole weight: 622.18.
RUE OIL
RUE OIL. Alternative Names: oilofrue; Oils,rue; RUE ESSENCE OLIFFAC; RUE OIL; FEMA 2994; RUTA GRAVEOLENS (RUE) OIL; RUE; Rlle oil. CAS No. 8014-29-7. Molecular formula: CAS: 8014-29-7.
Ru(II)-(R)-Pheox catalyst
Ru(II)-(R)-Pheox catalyst. Uses: Transition metal catalysts. Alternative Names: Ruthenium(1+), tetrakis(acetonitrile)[2-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl-κN3]phenyl-κC]-, (OC-6-23)-, hexafluorophosphate(1-) (1:1); Tetrakis(acetonitrile)[2-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl-N]phenyl]ruthenium(II) hexafluorophosphate; Ruthenium tetrakis(acetonitrile)[2-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl-κN3]phenyl-κC]-hexafluorophosphate. Grades: ≥95%. CAS No. 1421679-43-7. Molecular formula: C23H24N5ORu.F6P. Mole weight: 632.50.
Rupatadine Fumarate
Rupatadine inhibits both platelet-activating factor (PAF) and histamine (H1) effects through its interaction with specific receptors. Alternative Names: 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2E)-2-Butenedioate. Grades: >98%. CAS No. 182349-12-8. Molecular formula: C26H26ClN3.C4H4O4. Mole weight: 532.03.
Ruthenium acetate
Ruthenium acetate. Alternative Names: RUTHENIUM ACETATE; Ruthenium triacetate. Grades: 95%. CAS No. 72196-32-8. Molecular formula: C6H9O6Ru. Mole weight: 278.2.
Ruthenium(III) chloride hydrate
Ruthenium(III) chloride is the chemical compound with the formula RuCl3. "Ruthenium(III) chloride" more commonly refers to the hydrate RuCl3·xH2O. Both the anhydrous and hydrated species are dark brown or black solids. The hydrate, with a varying proportion of water of crystallization, often approximating to a trihydrate, is a commonly used starting material in ruthenium chemistry. Uses: Ruthenium(iII) chloride hydrate is a highly insoluble thermally stable ruthenium source suitable for glass, optic and ceramic applications. chloride compounds can conduct electricity when fused or dissolved in water. Alternative Names: RUTHENIUM(+3)CHLORIDE HYDRATE; RUTHENIUM CHLORIDE, HYDROUS; RUTHENIUM(III) CHLORIDE HYDRATE; RUTHENIUM(III) CHLORIDE N-HYDRATE; RUTHENIUM(III) CHLORIDE; RUTHENIUM TRICHLORIDE HYDRATE; RUTHENIUM TRICHLORIDE N-HYDRATE; RutheniumchloridehydrateRu. Grades: hydrate. CAS No. 14898-67-0. Molecular formula: RuCl3. Mole weight: 207.43.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ release from ryanodine-sensitive intracellular stores in skeletal and cardiac muscle. Alternative Names: Ammoniated ruthenium oxychloride; Azane; ruthenium(2+); hexachloride; dihydrate; Ruthenium Red, 98%, pure. Grades: ≥98% (T). CAS No. 11103-72-3. Molecular formula: Cl6H42N14O2Ru3. Mole weight: 786.35.
Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3. Alternative Names: (R)-Ruxolitinib; INCB018424; R-INCB018424; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. Grades: >98%. CAS No. 941678-49-5. Molecular formula: C17H18N6. Mole weight: 306.37.
Ruxolitinib phosphate
Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Alternative Names: INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate. Grades: >98%. CAS No. 1092939-17-7. Molecular formula: C17H21N6O4P. Mole weight: 404.36.
RVT-501
RVT-501, also referred to E6005, is a selective phosphodiesterase 4 (PDE4) inhibitor (IC50 = 2.8 nM) with potential effect to treat atopic dermatitis. Alternative Names: E-6005; E6005; E6005; RVT-501; RVT501; RVT 501; lotamilast; methyl 4-[[3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl]carbamoyl]benzoate; E6005; methyl 4-(((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)amino)carbonyl)benzoate. CAS No. 947620-48-6. Molecular formula: C26H24N4O5. Mole weight: 472.49.
(S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride. Alternative Names: (S)-1-(2-Aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile HCl. CAS No. 1448440-51-4. Molecular formula: C7H10ClF2N3O. Mole weight: 225.62.
S-(1,2-Dichlorovinyl)-Glutathione
S-(1,2-Dichlorovinyl)-Glutathione is a fundamental constituent functioning as a detoxification catalyst facilitating the removal of a plethora of toxins and xenobiotics. Its primary objective lies in the selective targeting and metabolism of injurious substances, particularly pesticides and specific drug metabolites. Alternative Names: S-(1,2-Dichlorovinyl)glutathione; DCVG; 96614-59-4; S-(1,2-dichlorovinyl)-glutathione(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-[(E)-1,2-dichloroethenyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid. Grades: > 95%. CAS No. 96614-59-4. Molecular formula: C12H17Cl2N3O6S. Mole weight: 402.26.
(S)-1-Boc-5-(thiazolidine-3-carbonyl)pyrrolidin-3-one (CAS# 401564-36-1) is an intermediate used to prepare dipeptidyl peptidase IV (DPP-IV) inhibitors. Alternative Names: (2S)-4-oxo-2-[oxo(3-thiazolidinyl)methyl]-1-pyrrolidinecarboxylic acid tert-butyl ester; tert-butyl (2S)-4-oxo-2-(1,3-thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate. CAS No. 401564-36-1. Molecular formula: C13H20N2O4S. Mole weight: 300.37.
S1P Fluorescein
S1P Fluorescein is a S1P analog with natural erythro stereochemistry labelled at the terminus of the alkyl chain with fluorescein. Alternative Names: Sphingosine 1-phosphate fluorescein. Grades: >95%. Molecular formula: C39H52N3O11P. Mole weight: 769.82.
(S)-1-phenyl-1-((R)-pyrrolidin-2-yl)ethanol
(S)-1-phenyl-1-((R)-pyrrolidin-2-yl)ethanol. Alternative Names: (S)-1-Phenyl-1-((R)-pyrrolidin-2-yl)ethan-1-ol. CAS No. 1228033-52-0. Molecular formula: C12H17NO. Mole weight: 191.27.