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5'-DMT-cytidine (N-iBu)
5'-DMT-cytidine (N-iBu), an immensely potent antiviral nucleoside analog, conspicuously stands out in treating viral infections, for instance, the stubborn hepatitis B and C. Chemical biochemistry declares that it breaks in and incapacitates the viral DNA polymerase, curtailing the growth and spread of viruses within the body. Comprising of therapeutic powers beyond the virulent world, preliminary studies have also legitimized its probable role in the treatment of certain cancer genres. Grades: ≥ 98% by HPLC. Molecular formula: C34H37N3O8. Mole weight: 615.67.
5'-DMT-cytidine (N-PAC)
5'-DMT-cytidine (N-PAC), a compelling prospective anti-cancer drug, operates via regulation of DNA methylation, a key contributor to the progression of malignant tumors. Encouraging outcomes have emerged, evidently indicating its potential effectiveness in treating lung cancer, leukemia, and other malignancies. Grades: ≥ 98% by HPLC. Molecular formula: C38H37N3O9. Mole weight: 679.72.
5'-DMT-guanosine (N-Fmoc)
5'-DMT-guanosine (N-Fmoc). A derivative of nucleotides, this compound has far-reaching applications in biomedical research - chiefly, but not exclusively, in the creation of oligonucleotides. Fantastic potential is expected for new developments in treatments for cancer, viral infections, and other such diseases, with this compound acting as a key starting material. Grades: ≥ 98% by HPLC. Molecular formula: C46H41N5O9. Mole weight: 807.85.
5'-DMT-guanosine (N-iBu)
5'-DMT-guanosine (N-iBu) is an indispensable compound specifically aiming in studying neurological ailments such as Alzheimer's disease and Parkinson's disease. Grades: ≥ 98% by HPLC. Molecular formula: C35H37N5O8. Mole weight: 655.7.
5'-DMT-guanosine (N-PAC)
N-PAC, also known as 5'-DMT-guanosine, is an intriguing nucleotide analogue that holds promise in chemical biology research. Among its many properties, it stands out as a selective inhibitor of Francisella tularensis, the causative agent of tularemia. But that's just the tip of the iceberg- N-PAC may also have exciting implications for chemotherapy treatment of triple-negative breast cancer. With its multifaceted potential, N-PAC is a compound that is sure to pique the interest of researchers and clinicians alike. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O9. Mole weight: 719.74.
5'-DMT-N1-Methyl-PseudoUridine
5'-DMT-N1-Methyl-PseudoUridine is a pivotal compound in studying viral infections and gene therapeutic interventions. This compound orchestrates an inhibitory effect on viral replication. Distinguished by its unparalleled chemical configuration, it impeccably accommodates RNA modifications. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-N1-methylpseudoUridine; 5'-O-DMT-N1-methylpseudouridine; 5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine; 5-[(2S,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 875302-39-9. Molecular formula: C31H32N2O8. Mole weight: 560.59.
5'-DMT-N3-methyl-2'-deoxythymidine
5'-DMT-N3-methyl-2'-deoxythymidine is a vital compound playing a crucial role in studying and developing diagnostic tools and antiviral therapies for diseases like HIV / AIDS. It can be used to study viral replication and design potent antiretroviral drugs making it an indispensable tool in the fight against viral infections. Grades: ≥ 98% by HPLC. Molecular formula: C32H34N2O7. Mole weight: 558.62.
5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite
5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite is a phosphoramidite compound used in the synthesis of oligonucleotides. It is designed to incorporate a modified deoxyuridine nucleotide into DNA strands, which can enhance the stability and functionality of the synthesized oligonucleotides. This compound is used to improve the metabolic stability and binding affinity of the synthesized oligonucleotides, making them more suitable for specific biological applications such as gene regulation, and antisense therapy. Alternative Names: N-Hydroxysuccinimide carboxy-dT phosphoramidite; 2-Propenoic acid, 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoate; NHS-Carboxy-dT; 5'-Dimethoxytrityl-5-[3-acrylate NHS ester]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-DMT-5-NHS-carboxy-2'-deoxy-rU 3'-Phosphoramidite. CAS No. 1354695-41-2. Molecular formula: C46H52N5O12P. Mole weight: 897.91.
5'-DMT-PseudoUridine
5'-DMT-PseudoUridine, a pivotal compound within the field of biomedicine, plays a profound and indispensable part in the therapeutic approach towards various diseases, enabling the alteration of RNA molecules. Its unparalleled characteristics not only bolster RNA stability but also foster heightened protein synthesis and regulate cellular mechanisms. Alternative Names: SCHEMBL1750218; 144429-55-0; 5-((2S,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 144429-55-0. Molecular formula: C30H30N2O8. Mole weight: 546.57.
5'-DMT-uridine
5'-DMT-uridine is a remarkable compound, exhibiting its efficacy in the research of neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. It has unparalleled ability to induce neuroregeneration and shield neurons from oxidative stress. Grades: ≥ 98% by HPLC. Molecular formula: C30H30N2O8. Mole weight: 546.57.
5'-dUMPS
5'-dUMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with 2'-deoxypyrimidine-5'- monophosphate. Alternative Names: 2'- Deoxyuridine- 5'- O- monophosphorothioate, sodium salt. Grades: ≥ 97 % by HPLC. CAS No. 205379-91-5. Molecular formula: C9H13N2O7PS (free acid). Mole weight: 324.3 (free acid).
5-epi Emtricitabine Carboxylic Acid
5-epi Emtricitabine Carboxylic Acid is an impurity of 5-epi Emtricitabine; an epimer of Emtricitabine which is a nucleoside reverse transcriptase inhibitor approved for treatment of HIV-1. Emtricitabine also has antagonistic activity against the hepatitis B virus. Alternative Names: (2R,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid. Molecular formula: C8H8FN2O4S. Mole weight: 261.23.
5-Ethoxymethyluridine
5-Ethoxymethyluridine, a remarkable biomedicine, stands as an invaluable asset for combatting an extensive array of diseases. Functioning as a nucleoside analog, it significantly hinders viral replication, rendering it indispensable in the battle against RNA viruses. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(ethoxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 95468-92-1. Molecular formula: C12H18N2O7. Mole weight: 302.28.
5-Ethyl-2'-deoxyuridine-d5
Isotope labelled 5-Ethyl-2'-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use. Alternative Names: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Molecular formula: C11H11D5N2O5. Mole weight: 261.29.
5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a remarkable antiviral compound, used in research of herpes simplex virus (HSV) infections. By functioning as a nucleoside analog and effectively hampering viral DNA enhancement, it efficaciously obstructs viral replication. The distinctive structure of this compound renders it exceptionally promising for extensive biomedical exploration and drug development directed towards HSV-associated afflictions. Alternative Names: Uridine, 2'-deoxy-5-ethyl-, 3',5'-bis(p-chlorobenzoate). Grades: 98%. CAS No. 25137-84-2. Molecular formula: C25H22Cl2N2O7. Mole weight: 533.36.
5-Ethyl-4-thiouridine
5-Ethyl-4-thiouridine is a paramount biomedical compound, intricately contributing to nucleotide research. Profoundly utilized as a chemical probe in RNA modification studies, this compound augments inquiries into the ramifications of thiouridine on RNA's structure and functionality. Manifesting its significance in relation to ailments encompassing cancer, RNA-related disorders and viral infections, it fosters comprehension of its disease-associated role. Alternative Names: Uridine, 5-ethyl-4-thio-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 148744-32-5. Molecular formula: C11H16N2O5S. Mole weight: 288.32.
A useful template for the development of A2B adenosine receptor agonists. It was confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor. Alternative Names: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide; 2',3'-O-isopropylidene-NECA. CAS No. 39491-53-7. Molecular formula: C15H20N6O4. Mole weight: 348.36.
5'-Ethylcarboxamido-adenosine
5'-Ethylcarboxamido-adenosine, a remarkable biomedicine, exhibits its prowess in cancer therapeutics. This extraordinary compound operates as an adenosine receptor agonist, effectively restraining the proliferation of malignant cells while orchestrating apoptosis. Uses: Vasodilator agents. Alternative Names: NECA; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamide; 5'-Ethylcarboxamido-D-adenosine. Grades: ≥ 95% by HPLC. CAS No. 35920-39-9. Molecular formula: C12H16N6O4. Mole weight: 308.29.
5-Ethylcarboxy-dC(Bz) Phosphoramidite
5-Ethylcarboxy-dC(Bz) Phosphoramidite is a modified phosphoramidite where the cytosine base is functionalized with an ethylcarboxy group at the 5-position and protected with a benzoyl (Bz) group on the exocyclic amine. The sugar moiety is designed with a 3'-phosphoramidite functionality for compatibility with automated DNA synthesis. This compound is commonly used to introduce chemically modified cytosine residues into oligonucleotides, enabling studies on DNA-protein interactions, epigenetic modifications, and the effects of base alterations on nucleic acid stability and function. It is particularly useful in therapeutic oligonucleotide development and molecular biology research. Alternative Names: 5-Pyrimidinecarboxylic acid, 4-(benzoylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-, ethyl ester; 5-Carboxy-dC-CE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-5-ethylcarboxy-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-carbethoxy-C(Bz) amidite. Grades: ≥95%. CAS No. 1535202-71-1. Molecular formula: C49H56N5O10P. Mole weight: 905.97.
5-Ethylcytidine
5-Ethylcytidine is a vital compound extensively used in the biomedical industry for developing antiviral and antitumor drugs. Alternative Names: 5-ethyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 56367-98-7. Molecular formula: C11H17N3O5. Mole weight: 271.27.
5-Ethyluridine
5-Ethyluridine, a remarkable biomedicine, occupies a pivotal position in the scientific realm, facilitating extensive exploration of pharmacological realms. Notably, this compound finds widespread employment in the synthesis and formulation of antiviral agents, with a particular focus on countering the perilous human immunodeficiency virus (HIV). Alternative Names: Uridine, 5-ethyl-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 25110-76-3. Molecular formula: C11H16N2O6. Mole weight: 272.25.
5-Ethynyl-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-β-D-ribofuranosyl)imidazo-4-carbonitrile is a compound useful in organic synthesis. Alternative Names: 5-Ethynyl-1-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1H-imidazole-4-carbonitrile. CAS No. 147212-83-7. Molecular formula: C29H53N3O4Si3. Mole weight: 592.01.
5-Ethynyl-1-(β-D-ribofuranosyl)-imidazo-4-carbonitrile is a compound useful in organic synthesis. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-ETHYNYLIMIDAZOLE-4-CARBONITRILE; 1H-Imidazole-4-carbonitrile, 5-ethynyl-1-beta-D-ribofuranosyl-; 5-Ethynyl-1-(beta-D-ribofuranosyl)-imidazo-4-carbonitrile; SCHEMBL9697576; CHEMBL4463936; OAMMFSMFVAEFOI-GWOFURMSSA-N; 5-ETHYNYL-1-(B-D-RIBOFURANOSYL)-IMIDAZO-4-CARBONITRILE; 5-Ethynyl-1-(?-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carbonitrile. CAS No. 126004-13-5. Molecular formula: C11H11N3O4. Mole weight: 249.22.
5-Ethynylcytidine
5-Ethynylcytidine is an eminent biomedical compound, employed as a nucleoside analog. It vigorously impedes viral replication and ushers in the righteous realm of apoptosis within malignant cells. Indeed, its profound efficacy can be attributed to its tenacious interference with nucleic acid research and development and relentless disruption of protein functionality. Alternative Names: 5-ethynyl-cytidine. Grades: ≥ 97% (HPLC). CAS No. 65223-78-1. Molecular formula: C11H13N3O5. Mole weight: 267.24.
5-Ethynylpyrimidine
5-Ethynylpyrimidine, an indispensable compound within the biomedical sector, assumes a pivotal function in the synthesis of pharmaceuticals and innovative drug candidates targeting a myriad of diseases. Its exceptional attributes facilitate profound investigations crucial for advancing therapeutic interventions across diverse medical domains including cancer, viral infections, and neurological disorders. Alternative Names: Pyrimidine, 5-ethynyl-(9CI). Grades: 95%. CAS No. 153286-94-3. Molecular formula: C6H4N2. Mole weight: 104.11.
5-Ethynyl-UTP
5-Ethynyl-UTP is a compound acting as a ubiquitous substrate to foster DNA research and development and modification. Alternative Names: 5-Ethynyluridine 5'-(tetrahydrogen triphosphate); 5-Ethynyl-deoxyuridine triphosphate; 5-Ethynyl uridine-triphosphate. Grades: ≥95% by HPLC. CAS No. 1004955-96-7. Molecular formula: C11H15N2O15P3. Mole weight: 508.16.
5'-Ferrocene CE Phosphoramidite
5'-Ferrocene CE Phosphoramidite is an oligonucleotide synthesis reagent that adds the electromagnetic group ferrocene to the oligonucleotide chain for application in oligonucleotide labeling. The absorption wavelength of 5'-Ferrocene CE Phosphoramidite is 438 nm and the extinction coefficient is 230M-1 cm-1. Alternative Names: 5'-Ferrocene Amidite; N-Ferrocenoyl-6-aminohexan-1-(2-cyanoethyl-diisoproylamino phoshoramidite). Molecular formula: C26H40FeN3O3P. Mole weight: 529.44.
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a highly efficacious synthetic nucleoside analog utilized in the research of human immunodeficiency virus (HIV) infection. Its mechanism of action involves robust inhibition of HIV reverse transcriptase, impeding viral replication and significantly ameliorating viral burden. Alternative Names: 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-β-L-ribofuranosyl)-uracil; [(2R,5S)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate. CAS No. 1421336-32-4. Molecular formula: C11H11FN2O5. Mole weight: 270.22.
5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is also known as F-deoxy-F-BzAraU, utilized in the research of specific DNA viruses including herpes simplex and varicella-zoster. Through hinderance of viral DNA replication, it effectively curbs the dissemination and development of viral infections. Alternative Names: 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-L-arabinofuranosyl)-5-fluoro-. CAS No. 178687-87-1. Molecular formula: C23H18F2N2O7. Mole weight: 472.40.
5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a robust compound, used in research of diverse viral infections, breast, lung and gastrointestinal tumors. Embodying exceptional inhibitory activity, this compound serves as an invaluable asset for the research and development of both antiviral and antitumor. Alternative Names: 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-β-L-lyxofuranosyl)-uracil. Grades: ≥95%. Molecular formula: C28H24F2N2O5. Mole weight: 506.51.
5-Fluoro-1-(β-D-ribopyranosyl)-2,4(1H,3H)-pyrimidinedione is a remarkable compound, showcasing its antiviral properties. This concoction exerts a inhibitory efficacy against certain RNA virus strains. Its modus operandi lies in its adeptness at impeding viral replication through disruption of the intricate enhancement of viral genetic material. Alternative Names: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-β-D-ribopyranosyl-; 5-fluoro-1-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 77180-80-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluoro-1-(b-L-ribofuranosyl)-uracil
5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a powerful antineoplastic compound, exhibiting immense potential in research of diverse malignancies. Renowned for its impact on inhibiting DNA enhancement and impeding cell proliferation, this remarkable compound emerges as an invaluable asset in the research and development of oncology. Alternative Names: 1-beta-L-Ribofuranosyl-5-fluorouracil; L-5-Fluorouridine; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione; 5-Fluoro-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; L-β-Ribofuranosyl-5'-fluorouracil. Grades: 95%. CAS No. 77210-26-5. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluoro-2'-deoxyuridine 5'-Monophosphate Ammonium Salt (up to 20% 3'-monophosphate)
5-Fluoro-2'-deoxyuridine 5'-Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity. Alternative Names: 2'-Deoxy-5-fluoro-5'-uridylic Acid Ammonium Salt. Grades: 90%. Molecular formula: C9H12FN2O8P xNH3. Mole weight: 326.17.
5-Fluoro-2'-O-methyl-4-(methylithio)uridine
5-Fluoro-2'-O-methyl-4-(methylithio)uridine is a potent compound, garnering significant attention owing to its exceptional efficacy in research of a myriad of viral infections. Its mechanism of action lies in proficiently inhibiting viral replication. Alternative Names: 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-4-methylsulfanylpyrimidin-2-one; 5-FLUORO-2'-O-METHYL-4-(METHYLTHIO)PYRIMIDIN-2-ONE. Grades: 95%. CAS No. 869222-67-3. Molecular formula: C11H15FN2O5S. Mole weight: 306.22.
5-Fluoro-2'-O-methyl-4-thiouridine
5-Fluoro-2'-O-methyl-4-thiouridine is an esteemed compound, unraveling itself through potent antiviral attributes. With astute acumen, this compound assiduously curbs viral replication, emerging as an invaluable asset in the research of influenza infection. Alternative Names: 5-FLUORO-2'-O-METHYL-4-THIOURIDINE. Grades: 95%. CAS No. 869355-51-1. Molecular formula: C10H13FN2O5S. Mole weight: 292.29.
5-Fluoro-2'-O-methyluridine
5-Fluoro-2'-O-methyluridine is a highly bioactive nucleoside compound, finding extensive utilization in the research and development of groundbreaking antiviral medications. Boasting remarkable potential, this compound showcases inhibitory efficacy against distinct RNA viruses. Alternative Names: 5-Fluoro-2'-O-methyl-D-uridine; 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. CAS No. 61671-80-5. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5-Fluoro-3'-beta-C-methyluridine
5-Fluoro-3'-beta-C-methyluridine is an immensely powerful antiviral entity, exhibiting inhibitory efficacy against select RNA viruses, notably hepatitis C virus and Zika virus. Focusing on its modus operandi, it exerts its effects by markedly impeding theenhancement and replication of viral RNA. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-4-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fluoro-3'-C-methyluridine. Grades: ≥95%. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5-Fluoro-4'-C-methylcytidine
5-Fluoro-4'-C-methylcytidine, an exceptional antiviral compound, exhibits remarkable potential in biomedical applications for targeting diverse viral infections. Its unparalleled efficacy extends to RNA viruses, such as hepatitis C virus (HCV) and the notorious SARS-CoV-2. This nucleotide analog disrupts viral RNA synthesis, effectively impeding viral replication. Captivating studies have unveiled its promising role as a therapeutic agent for combating viral diseases, thereby instigating renewed interest in intensified research and development of cutting-edge antiviral treatments. Proceeding into the realm of this scientific wonder, we embark upon a profound exploration. Alternative Names: Cytidine, 5-fluoro-4'-C-methyl-; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one; 4-Amino-1-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 791585-24-5. Molecular formula: C10H14FN3O5. Mole weight: 275.23.
5-Fluoro-4'-C-methyluridine
5-Fluoro-4'-C-methyluridine is a pivotal chemical compound widely employed in the biomedical sector, showcasing remarkable antiviral attributes. It is tailored for research of viral infections. Alternative Names: Uridine, 5-fluoro-4'-C-methyl-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 660845-69-2. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5-Fluoro-4'-thio-cytidine
5-Fluoro-4'-thio-cytidine is a remarkably potent antiviral compound extensively employed in the biomedical sector, acting a cytidine-derived substance. This compound proves integrally indispensable for research of combatting viral maladies. Grades: ≥95%. Molecular formula: C9H12FN3O4S. Mole weight: 277.27.
5-Fluoro-4'-thiouridine
5-Fluoro-4'-thiouridine is an influential pharmaceutical compound, used for studying diverse ailments, encompassing leukemia, pancreatic cancer and viral afflictions. Its inhibitory effects against both viruses and cancer cells are attributed to the inhibition of RNA enhancement and the initiation of apoptosis. Alternative Names: Uridine, 5-fluoro-4'-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grades: ≥95%. CAS No. 56527-42-5. Molecular formula: C9H11FN2O5S. Mole weight: 278.26.
5-Fluoro-6-iodouridine
5-Fluoro-6-iodouridine is an exceptionally powerful compound with remarkable antiviral attributes due to its distinctive amalgamation of fluorine and iodine moieties. It operates by proficiently impeding viral replication while concurrently diminishing the viral burden. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-6-iodopyrimidine-2,4-dione. Grades: ≥ 95%. CAS No. 87818-06-2. Molecular formula: C9H10FIN2O6. Mole weight: 388.09.
5-Fluorocytosine arabinoside
5-Fluorocytosine arabinoside, an exceptionally powerful antineoplastic agent extensively applied for the management of diverse malignancies such as leukemia and solid tumors, expertly imparts its therapeutic effects through the restraint of DNA synthesis and the instigation of cellular demise. Alternative Names: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one; Fluorocytosine arabinoside; Arafluorocytosine; Ara-FC; 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidin-2-one. Grades: 98%. CAS No. 4298-10-6. Molecular formula: C9H12FN3O5. Mole weight: 261.21.
5-Fluoro-dUMP
5-Fluoro-dUMP is a reagent used in the synthesis of diaminomitosene nucleotide derivatives with antineoplastic activity. Alternative Names: (5F-dUMP); 5-Fluoro-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 88410-68-8. Molecular formula: C9H12N2O8PF (free acid). Mole weight: 326.17 (free acid).
5-Fluoro-dUTP
5-Fluoro-dUTP is used as the substitute for DNA synthesis catalyzed by DNA polymerases a or Ãfrom calf thymus. 5-Fluoro-dUTP is incorporated into DNA and the incorporated pyrimidine analogs supported further elongation of DNA. Alternative Names: 5-F-dUTP; 5-Fl-dUTP; 5-Fluoro-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.13 (free acid).
5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine can be used in method for using 5-flucytosine for real-time monitoring the deamination process of HIV-1 DNA. Alternative Names: 2'-Deoxy-5-fluoro-4-O-(2,4,6-trimethylphenyl)uridine; 2'-Deoxy-5-fluoro-4-O-(2,4,6-trimethylphenyl)-uridine. CAS No. 141120-63-0. Molecular formula: C18H21FN2O5. Mole weight: 364.37.
5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine can be used in pharmacological activity and biological study of compositions and methods for severe acute respiratory syndrome (SARS) treatment. Alternative Names: 5-fluoro-2'-O-methyl-4-O-(2,4,6-trimethylphenyl)-uridine. CAS No. 444788-89-0. Molecular formula: C19H23FN2O6. Mole weight: 394.39.
5-Fluoropyrimidin-2-One beta-Ribofuranoside
5-Fluoropyrimidin-2-One beta-Ribofuranoside is an antiviral compound with applications in the research of diverse ailments, encompassing specific cancers and viral afflictions. By impeding crucial DNA research and development and replication processes, this pharmaceutical compound thwarts cancer cell propagation and viral replication. Alternative Names: 1beta-D-Ribofuranosyl-5-fluoropyrimidin-2(1H)-one; 5-fluorozebularine; 5-F-Zebularine; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one; 5-Fluoro-zebularine; 5-Fpor; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 5-Fluoropyrimidin-2-one riboside; 5-Fluoropyrimidin-2-one ribonucleoside; 5-fluoropyrimidin-2-one-ribonucleoside; NSC 318509; 2(1H)-Pyrimidinone, 5-fluoro-1-beta-D-ribofuranosyl-. CAS No. 64967-16-4. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
5-Fluorouracil N-b-D-glucuronide
5-Fluorouracil N-b-D-glucuronide is a noteworthy pharmaceutical compound, acting as an illustrious glucuronidated derivative intricately intertwined with 5-Fluorouracil. It can be used in research of malignancies encompassing breast, colon and dermal cancer. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-b-D-glucopyranuronic acid; 5-Fluoro-1-(b-D-glucuronopyranosyl)uracil. CAS No. 66048-45-1. Molecular formula: C10H11FN2O8. Mole weight: 306.20.
Protected 5-Fluorouracil N-β-D-Glucuronide, a derivative of 5-Fluorouracil. 5-Fluorouracil N-β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. CAS No. 77476-81-4. Molecular formula: C17H19FN2O11. Mole weight: 446.34.
5-Fluoro Uridine
5-Fluoro uridine is a fluorinated analog of uridine, which is a nucleoside that forms part of RNA. 5-Fluoro uridine is a valuable compound in both research and clinical settings due to its ability to disrupt RNA function and inhibit cancer cell growth. Its fluorinated structure makes it a potent analog of uridine with significant biological activity. Alternative Names: 5-Fur; Uridine, 5-fluoro-; Fluorouridine; 5-fluoro-1-(beta-d-ribofuranosyl)uracil; FUrd; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-fluoro-D-uridine; 1-beta-D-Arabinofuranosyl-5-fluoro-(1H,3H)-pyrimidine-2,4-dione; 5-FUrd; NSC 146604; NSC 519273; 5-Fluorouridine. Grades: 97%. CAS No. 316-46-1. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluorouridine-13C,15N2
5-Fluorouridine-13C,15N2 is a compound useful in organic synthesis. Alternative Names: 5-FU-3C, 15N2. Grades: 98%; 98.8% atom 13C,15N. Molecular formula: C8[13C]H11F[15N]2O6. Mole weight: 265.17.
5-Fluorouridine-5'-diphosphate
5-Fluorouridine-5'-diphosphate, a pivotal biomedicine entity, demonstrates profound significance in diverse ailments, particularly cancer. Operating as an efficient anticancer intervention, this derivative effectively impedes the expansion and reproduction of malignant cells. Its mechanism involves interrupting DNA synthesis, thereby facilitating the control over specific cancer variants. Alternative Names: 5-Fluorouridine 5'-(trihydrogen diphosphate); Uridine, 5-fluoro-, 5'-(trihydrogen pyrophosphate); Uridine, 5-fluoro-, 5'-pyrophosphate; 5-Fluoro-UDP; 5-Fluorouridine 5'-diphosphate; 5-Fluorouridine diphosphate; 5-F-UDP. Grades: ≥97% by HPLC. CAS No. 803-98-5. Molecular formula: C9H13FN2O12P2. Mole weight: 422.15.
5-Fluorouridine 5'-Diphosphate Galactose
5-Fluorouridine 5'-Diphosphate Galactose is a crucial molecule in biomedicine used for treating certain diseases. It plays a vital role as a competitive inhibitor of UDP-galactose 4-epimerase, which is involved in the synthesis of glycoproteins and glycolipids. This product finds applications in the development of targeted therapies for cancer, as it acts by inhibiting the galactosylation process essential for tumor growth and metastasis. Alternative Names: Fudp-5. CAS No. 92748-40-8. Molecular formula: C15H23FN2O17P2. Mole weight: 584.29.
5-Fluorouridine-5'-monophosphate sodium salt
5-fluorouridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component. It has a role as a drug metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and an organofluorine compound. It derives from a uridine 5'-monophosphate. Alternative Names: 5'-Uridylic acid, 5-fluoro-, disodium salt; 5F-UMP disodium salt; 5-Fluoro-5'-uridylic acid disodium salt; 5-Fluorouridine 5'-monophosphate disodium salt; 5-Fluorouridine 5'-phosphate disodium salt; 5-Fluorouridine monophosphate disodium salt; 5-Fluorouridylic acid disodium salt; 5-fluorouridine 5'-(dihydrogen phosphate) disodium salt; 5-Fluoro-UMP disodium salt. Grades: ≥97%. CAS No. 67550-10-1. Molecular formula: C9H10FN2Na2O9P. Mole weight: 386.14.
5-Fluorouridine-5'-O-b-D-galactopyranoside
5-Fluorouridine-5'-O-b-D-galactopyranoside is also known as FUG, meticulously employed for the efficacious research of an array of intricate and multifaceted cancers. It magnanimously arrests the pernicious proliferation and dissemination of malignant cell. Alternative Names: Gal-FUrd; 5-Fluoro-D-uridine-5'-O-b-D-galactopyranoside; 5'-O-beta-D-Galactosyl-5-fluorouridine; 5'-O-Galactosyl-5-fluorouridine; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grades: 95%. CAS No. 149965-92-4. Molecular formula: C15H21FN2O11. Mole weight: 424.33.
5-Fluoro-UTP trisodium
5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug. Alternative Names: 5-Fluoro-uridine-5'-triphosphate trisodium; 5-F-UTP trisodium; 5-Fluorouridine 5'-(tetrahydrogen triphosphate) trisodium. Molecular formula: C9H14FN2Na3O15P3. Mole weight: 571.10.
5-Formyl-2',3'-O-(1-methylethylidene)-cytidine
5-Formyl-2',3'-O-(1-methylethylidene)-cytidine is an intermediate in 5-Formylcytidine synthesis. 5-Formylcytidine is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Alternative Names: 5-Formyl-2',3'-O-(1-methylethylidene)cytidine; Furo[3,4-d]-1,3-dioxole Cytidine Deriv. CAS No. 153535-36-5. Molecular formula: C13H17N3O6. Mole weight: 311.29.
5-Formyl-2'-deoxyuridine-5'-Triphosphate
5-Formyl-2'-deoxyuridine-5'-Triphosphate - an essential synthetic nucleotide that's proven incredibly effective in biomedical research. Most notably, its use in conjunction with DNA polymerases has provided invaluable insight into the mechanisms behind mutations and their correction. But that's not all - this revolutionary molecule has even been shown to increase the sensitivity of cancer cells to chemotherapy drugs. Researchers worldwide trust 5-Formyl-2'-deoxyuridine-5'-Triphosphate to deliver consistent and reliable results whilst paving the way for new discoveries. Alternative Names: 5-Formyl-dUTP; 5-CHO-dUTP; 5-Fo-dUTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N2O15P3. Mole weight: 496.10.
5-Formyl-2'-O-methyluridine
5-Formyl-2'-O-methyluridine is an intriguing compound boasting remarkable potential in combatting the propagation of specific viral ailments. Its aptitude to encumber the RNA enhancement process of RNA viruses. Alternative Names: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde. CAS No. 220090-12-0. Molecular formula: C11H14N2O7. Mole weight: 286.24.
5-formylcytidine
5-Formylcytidine is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Alternative Names: Cytidine, 5-formyl-; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde; cytidine, 6-formyl-. Grades: 98%. CAS No. 148608-53-1. Molecular formula: C10H13N3O6. Mole weight: 271.23.
5-Formyl-dC
5-Formyl-dC, an indispensable reagent in the biomedicine field, occupies a pivotal position owing to its unparalleled characteristics. Its significance lies in facilitating the synthesis of tailored nucleic acids, thereby facilitating in-depth exploration of various research domains. Remarkably, this compound imparts unprecedented opportunities for the discovery of novel therapeutic agents and diagnostic instruments targeting a broad spectrum of ailments spanning cancer and hereditary anomalies. Alternative Names: fdC; 5-Formyl-2'-deoxycytidine. Grades: ≥ 95% by HPLC. CAS No. 137017-45-9. Molecular formula: C10H13N3O5. Mole weight: 255.23.
5-Formylindole-CE Phosphoramidite
5-Formylindole-CE Phosphoramidite, a critical reagent utilized to create modified nucleotides integrating into synthetic DNA/RNA molecules, is a significant contributor to the development of specific and effective drugs employed for the remediation of viral and bacterial infections, genetic disorders, cancer, and other fatal diseases. Alternative Names: 5'-Dimethoxytrityl-2'-deoxy-3-formylindole-ribofuranosyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C44H50N3O7P. Mole weight: 763.86.
5-Formyl-UTP
5-Formyl-UTP is an indispensable constituent predominantly applied in investigations pertaining to RNA modifications and transcriptional regulation. This invaluable compound contributes to the research of diverse medical conditions, including cancer. By acting as a substrate for RNA labeling and detection, it expedites the exploration of these ailments. Furthermore, its integration into RNA sequences facilitates an enhanced comprehension of RNA metabolism and intricate cellular mechanisms. Alternative Names: 5-Formyluridine-5'-Triphosphate; 5-fUTP; 5-FoUTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N2O16P3. Mole weight: 512.15.
5-(Furan-2-yl)-2'-deoxyuridine
5-(Furan-2-yl)-2'-deoxyuridine, a groundbreaking antiviral compound widely employed in the field of biomedicine, holds remarkable potential for combatting pernicious herpes viruses. Through its remarkable capacity to impede viral DNA synthesis, it effectively stifles the replication of the herpes simplex virus (HSV), consequently furnishing a promising therapeutic avenue for HSV infections. Grades: ≥ 97%. CAS No. 92233-50-6. Molecular formula: C13H14N2O6. Mole weight: 294.26.
5'-(Furan-2-yl)-2'-O-methyluridine
5'-(Furan-2-yl)-2'-O-methyluridine, an extraordinary biomedicine compound, exhibits remarkable efficacy in combating a wide range of viral infections, such as hepatitis C and influenza. By impeding RNA synthesis, this nucleoside analog effectively obstructs viral replication, thereby curbing their proliferation. Distinguished by its distinctive structure, it precisely targets viral polymerases, presenting a highly promising and pioneering approach to antiviral therapy. Alternative Names: 5-(Furan-2-yl)-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Furan-2-yl-2'-O-Methyl uridine. Grades: ≥95%. CAS No. 2095417-32-4. Molecular formula: C14H16N2O7. Mole weight: 324.29.
5'-(Furan-2-yl)-5'-O-DMT-2'-O-methylcytidine
5'-(Furan-2-yl)-5'-O-DMT-2'-O-methylcytidine is a remarkable biomedical compound, operating as an unrivaled antiviral warrior. This astounding compound zealously stifles viral replication, catapulting it to the forefront of viral ailment research. By engaging in a precisely orchestrated dance with intricate RNA viruses, it emerges as an illustrious contender for the annihilation of these infectious assailants. Alternative Names: 5-Furan-2-yl-2'-O-methyl-5'-O-DMTr-cytidine; 5-Furan-2-yl-2'-O-methyl-5'-O-(4,4'-dimethoxytrityl)cytidine. Grades: ≥95%. CAS No. 2095417-02-8. Molecular formula: C35H35N3O8. Mole weight: 625.67.
5-(Furan-2-yl)-dC CEP
5-(Furan-2-yl)-dC CEP, a fundamental compound extensively utilized in the biomedical field, holds immense significance for the synthesis of altered nucleosides. Its indispensable role lies in the progression of pharmaceutical agents aimed at combatting an array of ailments including malignant neoplasms, viral afflictions, and hereditary disorders. CAS No. 1119734-65-4. Molecular formula: C50H54N5O9P. Mole weight: 899.97.
5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran Isoleucine
5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran Isoleucine is an intermediate in the synthesis of Fructose-Isoleucine, an amadori compound that is formed in food as a result of the maillard reactions. Molecular formula: C17H30N2O7. Mole weight: 374.43.
5'-Hexachloro-Fluorescein CE Phosphoramidite(6-HEX)
5'-Hexachloro-Fluorescein CE Phosphoramidite (6-HEX), a cutting-edge phosphoramidite fluorescent dye reagent, expertly designed for both the labeling and detection of DNA and RNA sequences. With its superior sensitivity, this reagent is ideal for use in a variety of experiments, including gel electrophoresis, high-throughput sequencing, and hybridization. This innovative technology not only boasts impressive capabilities for real-time PCR, but is also an essential tool for gene expression analysis. Experience the unparalleled precision of 6-HEX, and revolutionize your research today. Grades: >95% by HPLC. Molecular formula: C46H52CI6N3O10P. Mole weight: 1050.62.