BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Amylostatin XG Octaacetate | Amylostatin XG Octaacetate is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Synonyms: [1S-(1α,4α,5β,6α)]-4-O-[2,3-Di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl]-D-glucopyranose; D-Glucopyranose, 4-O-[2,3-di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl]-, 1,2,3,6-tetraacetate, [1S-(1α,4α,5β,6α)]-. CAS No. 85747-82-6. Molecular formula: C39H53NO23. Mole weight: 903.83. |  |
| Amylostatin XG Octamethoxybenzyl Ether | Amylostatin XG Octamethoxybenzyl Ether is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Molecular formula: C97H109NO21S. Mole weight: 1656.96. | |
| AMZ30 | AMZ30, a PME-1 inhibitor, could inhibit PME-1 irreversiblely and be significant in the pharmacological study of determinating the demethylated PP2A function. IC50: 600 nM. Uses: Amz30 is a pme-1 inhibitor that could inhibit pme-1 irreversiblely and be significant in the pharmacological study of determinating the demethylated pp2a function. Synonyms: AMZ30; AMZ 30; AMZ-30; CHEMBL1550905; ML136; ML 136; ML-136; MLS002699139; SCHEMBL16194668; SCHEMBL16194670. Grade: 98%. CAS No. 1313613-09-0. Molecular formula: C19H12FN3O6S2. Mole weight: 461.44. | |
| AN 0128 | AN0128 is a broad-spectrum antibacterial and anti-inflammatory agent containing boron. The minimum inhibitory concentrations (MIC) of AN0128 against S. aureus, S. epidermidis, P. acnes, B. subtilis are 1, 0.5, 0.3 and 1 μg/mL, respectively. AN0128 is a tumor necrosis factor α (TNF-α) inhibitor that may be used in the treatment of atopic dermatitis. Synonyms: AN0128; 3-Hydroxypyridine-2-carbonyloxy-bis(3-chloro-4-methylphenyl)borane; ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone; 2-Pyridinecarboxylic acid, 3-hydroxy-, anhydride with bis(3-chloro-4-methylphenyl)borinic acid; 2-({[Bis(3-chloro-4-methylphenyl)boranyl]oxy}carbonyl)pyridin-3-ol; CRM-0005; ONT-0001. Grade: ≥98%. CAS No. 872044-70-7. Molecular formula: C20H16BCl2NO3. Mole weight: 400.06. | |
| AN-207 | AN-207, a new targeted cytotoxic analog of LH-RH. AN-207 consists of the agonist [D-Lys(6)]LH-RH linked to 2-pyrrolino-doxorubicin, an intensely potent derivative of doxorubicin. Targeted chemotherapy with AN-207 could be considered for treatment of advanced prostate cancer. Synonyms: AN-207; AN 207; AN207. CAS No. 79910-83-9. | |
| AN2718 | AN2718, a novel boron-containing small molecule, is a member of a new class of antifungals, benzoxaboroles, which inhibit fungal growth by blocking protein synthesis. Initial data have suggested that it may be more effective than tavaborole for T. rubrum and T. mentagrophytes. Synonyms: 5-chlorobenzo[c][1,2]oxaborol-1(3H)-ol; AN2718; AN-2718; AN 2718. CAS No. 174672-06-1. Molecular formula: C7H6BClO2. Mole weight: 168.38. | |
| AN3199 | AN3199, a PDE4 inhibitor, was once studied as an anti-inflammatory agent. IC50: 94.5 nM. Uses: An3199 is a pde4 inhibitor and was once studied as an anti-inflammatory agent. Synonyms: AN 3199; AN-3199. Grade: 98%. CAS No. 1187187-10-5. Molecular formula: C17H18BNO5. Mole weight: 327.14. | |
| AN-3485 | AN-3485, a benzoxaborole analog, is a toll-like receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. Synonyms: 6-[4-(Aminomethyl)-2-chlorophenoxy]-2,1-benzoxaborol-1(3H)-ol; Benzenemethanamine, 3-chloro-4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)oxy]-. Grade: ≥98%. CAS No. 1213827-99-6. Molecular formula: C14H13BClNO3. Mole weight: 289.52. | |
| AN3661 | AN3661 is a potent antimalarial lead compound that targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). Synonyms: 3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)propanoic acid. Grade: 99%. CAS No. 1268335-33-6. Molecular formula: C10H11BO4. Mole weight: 206.00. | |
| AN-7 | AN-7 is a novel histone deacetylase inhibitor (HDACI) with anticancer activity in several cell lines. Synonyms: 3-(5-[1,2]dithiolan-3yl-pentanoylamino)-propyl]-amide. CAS No. 691410-93-2. Molecular formula: C19H34N2O2S4. Mole weight: 450.73. | |
| AN7973 | AN7973 blocks intracellular parasite development and inhibits Cryptosporidium growth. It is orally active, possesses favorable safety, stability, and PK parameters. Synonyms: AN7973; 1620899-32-2; 2-Chloro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-4-(1H-pyrazol-1-yl)benzamide; SCHEMBL15937392AT28707. Grade: 99%. CAS No. 1620899-32-2. Molecular formula: C19H17BClN3O3. Mole weight: 381.62. | |
| ANA-12 | ANA-12 is a selective TrkB antagonist. ANA-12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Synonyms: ANA12; ANA 12; ANA-12. Grade: >98%. CAS No. 219766-25-3. Molecular formula: C22H21N3O3S. Mole weight: 407.49. | |
| ANA-773 | ANA773 is a Toll-like Receptor 7 (TLR7) agonist prodrug with potential immunostimulating activity. Upon oral administration, ANA773 is metabolized into its active form that binds to and activates TLR7, thereby stimulating dendritic cells (DCs) and enhancing natural killer cell (NK) cytotoxicity. TLR7 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity. Synonyms: ANA773; ANA 773; RG-7795. CAS No. 1174920-78-5. Molecular formula: C12H14N4O5S. Mole weight: 326.33. | |
| Anabasine DiHCl | A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: Pyridine, 3-(2-piperidinyl)?-, hydrochloride (1:2). Grade: > 95%. CAS No. 143924-48-5. Molecular formula: C10H14N2. 2 HCl. Mole weight: 234.86. | |
| Anacetrapib | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Synonyms: MK-0859; MK 0859; MK0859; Anacetrapib. Grade: 0.99. CAS No. 875446-37-0. Molecular formula: C30H25F10NO3. Mole weight: 637.518. | |
| Anagliptin | A pharmaceutical drug for the treatment of type 2 diabetes mellitus. Synonyms: N-[2-[[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide. Grade: > 95%. CAS No. 739366-20-2. Molecular formula: C19H25N7O2. Mole weight: 383.46. | |
| Anagrelide | Anagrelide is a phosphodiesterase inhibitor with antiplatelet activity with IC50 value of 36 nM for inhibition of phosphodiesterase 3. It inhibits the maturation of megakaryocytes into platelets, reducing both megakaryocyte hyperproliferation and differentiation. It is antithrombocythemic used for the treatment of overproduction of blood platelets. It is a synthetic quinazoline derivative and is used as is a platelet-reducing agent. It reduces platelet production through a decrease in megakaryocyte maturation. It inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. It is a drug used for the treatment of essential thrombocytosis or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. It was developed by Shire and has been listed. Uses: Anagrelide is used for the treatment of overproduction of blood platelets. it is a drug used for the treatment of essential thrombocytosis or overproduction of blood platelets. it also has been used in the treatment of chronic myeloid leukemia. Synonyms: 6,7-Dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one; 6-Chloro-1,2,3,5-tetrahydro iMidazo [2,1-b]quinazolin-2-one; Agrelin; Agrylin; Xagrid; Shire; Thromboreductin. Grade: 98%. CAS No. 68475-42-3. Molecular formula: C10H7Cl2N3O. Mole weight: 256.09. | |
| Anagrelide Hydrochloride | Anagrelide is a drug used for the treatment of essential thrombocytosis,or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. Uses: Platelet aggregation inhibitors. Synonyms: Anagrelide hydrochloride; BL 4162A; BL-4162A; BL4162A; Agrylin; Xagrid; GALE-401; Thromboreductin. Grade: >98%. CAS No. 58579-51-4. Molecular formula: C10H7Cl2N3O.HCl. Mole weight: 292.55. | |
| Anagrelide Impurity 2 | A metabolite of Anagrelide. Synonyms: Ethyl 2-(6-Nitro-2,3-dichlorobenzyl)glycine. Grade: > 95%. CAS No. 85325-11-7. Molecular formula: C11H12Cl2N2O4. HCl. Mole weight: 307.14 36.46. | |
| Anagrelide USP Related Compound A | An impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Synonyms: Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate; Anagrelide hydrochloride USP Related Compound A; Glycine, N-[(6-amino-2,3-dichlorophenyl)methyl]-, ethyl ester; Anagrelide Related Compound A; N-[(6-Amino-2,3-dichlorophenyl)methyl]glycine ethyl ester; USP Anagrelide Related Impurity A; Ethyl N-(2,3-dichloro-6-aminobenzyl)glcycine; Ethyl (2-amino-5,6-dichlorobenzyl)aminoacetate; Ethyl N-(6-amino-2,3-dichlorobenzyl)glycine; N-(6-Amino-2,3-dichlorobenzyl)glycine ethyl ester. Grade: ≥95%. CAS No. 70406-92-7. Molecular formula: C11H14Cl2N2O2. Mole weight: 277.15. | |
| Anagrelide USP Related Compound A hydrochloride | An impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Synonyms: Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate hydrochloride; Anagrelide hydrochloride USP Related Compound A hydrochloride; Glycine, N-[(6-amino-2,3-dichlorophenyl)methyl]-, ethyl ester, hydrochloride (1:x); Anagrelide Related Compound A hydrochloride; Anagrelide Related Compound A HCl; N-[(6-Amino-2,3-dichlorophenyl)methyl]glycine Ethyl Ester Hydrochloride; USP Anagrelide Related Impurity A hydrochloride. Grade: ≥95%. CAS No. 85325-12-8. Molecular formula: C11H14Cl2N2O2.xHCl. Mole weight: 277.15 (free base). | |
| Anagrelide USP Related Compound C | An impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Synonyms: Anagrelide related compound C; Ethyl 2-(5,6-dichloro-2-imino-1,2-dihydroquinazolin-3(4H)-yl)acetate hydrobromide; 3(4H)-Quinazolineacetic acid, 2-amino-5,6-dichloro-, ethyl ester, monohydrobromide; 3(4H)-Quinazolineacetic acid, 2-amino-5,6-dichloro-, ethyl ester, hydrobromide (1:1); Ethyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate hydrobromide; 2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide; USP Anagrelide Related Impurity C; Anagrelide hydrochloride USP Related Compound C. Grade: 95%. CAS No. 70381-75-8. Molecular formula: C12H13Cl2N3O2.HBr. Mole weight: 383.07. | |
| Anagrelide USP Related Impurity B | Anagrelide USP Related Impurity B is an impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Synonyms: 2-Amino-5,6-dichloro-3(4H)-quinazoline Acetic Acid; Anagrelide Impurity B. Grade: 95%. CAS No. 1159977-03-3. Molecular formula: C10H9Cl2N3O2. Mole weight: 274.10. | |
| Analgin | Analgin, is an non-opioid analgesic (pain reliever) and antipyretic (fever reducer) and is one of the most frequently used painkillers in the world. Uses: Commonly used in the past as a powerful painkiller and fever reducer. Synonyms: Dipyrone; NSC-73205; NSC 73205; NSC73205; Anador; Novalgin; Dipyron monohydrate; Methapyrone; sodium; [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-methylamino]methanesulfonate; hydrate. Grade: ≥95%. CAS No. 5907-38-0. Molecular formula: C13H18N3NaO5S. Mole weight: 351.35. | |
| Anamorelin | Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Synonyms: RC 1291; RC-1291; RC1291; ONO 7643; ONO-7643; ONO7643. CAS No. 249921-19-5. Molecular formula: C31H42N6O3. Mole weight: 546.7. | |
| Anamorelin Fumarate | Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. Synonyms: RC-1291 Fumarate; ONO-7643 Fumarate; RC1291 Fumarate; ONO7643 Fumarate; RC 1291 Fumarate; ONO 7643 Fumarate. Grade: >98%. CAS No. 339539-92-3. Molecular formula: C35H46N6O7. Mole weight: 662.78. | |
| Anamorelin HCl | Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Uses: For research used only. Synonyms: RC 1291; RC1291; RC-1291; RC 1291 HCl; ONO-7643; ONO7643; ONO 7643; Anamorelin hydrochloride. Grade: 98%. CAS No. 861998-00-7. Molecular formula: C31H43ClN6O3. Mole weight: 583.174. | |
| Anandamide-d4 | Anandamide (N-arachidonylethanolamine, AEA) is a brain lipid that binds to cannabinoid receptors with high affinity and mimics the psychoactive effects of plant-derived cannabiniod drugs, which is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid), an essential omega-6 fatty acid. Anandamide inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM. Synonyms: N-(2-Hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z-eicosatetraenamide. Grade: 99% atom D. CAS No. 946524-40-9. Molecular formula: C22H33D4NO2. Mole weight: 351.56. | |
| Anastrozole Diamide Impurity | Anastrozole Diamide Impurity is an impurity of Anastrozole, which is a medication used for the treatment of breast cancer in women after menopause. Synonyms: 2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanamide; α1, α1, α3, α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-Benzenediacetamide. Grade: > 95%. CAS No. 120512-04-1. Molecular formula: C17H23N5O2. Mole weight: 329.41. | |
| Anastrozole EP Impurity E | Anastrozole Impurity. Synonyms: 1,3-Benzenediacetonitrile, 5-(hydroxymethyl)-a1,a1,a3,a3-tetramethyl-. Grade: > 95%. CAS No. 120511-88-8. Molecular formula: C15H18N2O. Mole weight: 242.32. | |
| Anastrozole EP Impurity H | Anastrozole EP Impurity H is an impurity of Anastrozole, which is a medication used for the treatment of breast cancer in women after menopause. Synonyms: 2,2'-(5-methylbenzene-1,3-diyl)bis(2-methylpropanenitrile); 1,3-Benzenediacetonitrile, α1,α1,α3,α3,5-pentamethyl-; 1,3-Benzenediacetonitrile, α,α,α',α',5-pentamethyl-; α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile; 2,2'-(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile); 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile); 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile; 3,5-Bis(2-cyano-2-methylethyl)toluene; 3,5-Bis(2-cyanoprop-2-yl)toluene. Grade: ≥95%. CAS No. 120511-72-0. Molecular formula: C15H18N2. Mole weight: 226.32. | |
| Anastrozole EP Impurity I | Anastrozole Impurity. Synonyms: 2-[3-CHLOROMETHYL-5-(CYANO-DIMETHYL-METHYL)-PHENYL]-2-METHYL-PROPIONITRILE. Grade: > 95%. CAS No. 120511-91-3. Molecular formula: C15H17ClN2. Mole weight: 260.77. | |
| Anastrozole Impurity B | Anastrozole Impurity. Synonyms: α-Desmethyl Anastrozole. Grade: > 95%. CAS No. 1215780-15-6. Molecular formula: C16H17N5. Mole weight: 279.35. | |
| Anastrozole Impurity C | Anastrozole Impurity. Synonyms: 2,3-Bis[3-(1-cyano-1-methylethyl)-5-(1H,1,2,4-triazole-1-ylmethyl)phenyl]-2-methylpropionitrile. Grade: > 95%. CAS No. 1216898-82-6. Molecular formula: C30H31N9. Mole weight: 517.64. | |
| Anastrozole Impurity D | Anastrozole Impurity. Synonyms: 3,5-Bis(2-cyanoprop-2-yl)benzyl bromide. Grade: > 95%. CAS No. 120511-84-4. Molecular formula: C15H17BrN2. Mole weight: 305.22. | |
| Anastrozole Impurity E | Anastrozole Impurity. Synonyms: 3,5-Bis(2-cyanoprop-2-yl)bromobenzyl bromide. Grade: > 95%. CAS No. 1027160-12-8. Molecular formula: C15H16Br2N2. Mole weight: 384.12. | |
| Anastrozole Isomer | Anastrozole Impurity. Synonyms: Isoanastrozole. Grade: > 95%. CAS No. 120511-92-4. Molecular formula: C17H19N5. Mole weight: 293.37. | |
| Anastrozole Monoamide Mononitrile | Anastrozole Monoamide Mononitrile is an impurity of Anastrozole, which is a medication used for the treatment of breast cancer in women after menopause. Synonyms: 3-(1-Cyano-1-methylethyl)-alpha,alpha-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)benzeneacetamide; 2-{3-[(1H-1,2,4-Triazol-1-yl)methyl]-5-(2-cyanopropan-2-yl)phenyl}-2-methylpropanamide. Grade: > 95%. CAS No. 120512-03-0. Molecular formula: C17H21N5O. Mole weight: 311.39. | |
| Anatabine dicitrate | Anatabine dicitrate is a potent α4β2 nAChR agonist. It inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment. Grade: 99%. Molecular formula: C22H28N2O14. Mole weight: 544.46. | |
| Anavex 2-73 HCl | Anavex 2-73 is a mixed muscarinic and sigma-1/σ1 Receptor agonist with neuroprotective effects. Synonyms: Blarcamesine hydrochloride; AVex-73 hydrochloride; AE-37 hydrochloride. CAS No. 195615-84-0. Molecular formula: C19H24ClNO. Mole weight: 317.85. | |
| Anaxirone | Anaxirone is a synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. Uses: Antineoplastic agents. Synonyms: triglycidylurazol; Abbreviation: TGU; 1,2,4-triglycidylurazol. CAS No. 77658-97-0. Molecular formula: C11H15N3O5. Mole weight: 269.25. | |
| Ancarolol | Ancarolol is a beta-adrenergic blocker. Synonyms: (R,S)-2'-(3-(tert-Butylamino)-2-hydroxypropoxy-2-furanilid. Grade: 95%. CAS No. 75748-50-4. Molecular formula: C18H24N2O4. Mole weight: 332.39. | |
| Ancremonam | Ancremonam is a potent antibiotic with activity against Carbapenem-Resistant Enterobacteriaceae (MIC90 = 2 uM/mL). Ancremonam is potent in the presence of all classes of beta-lactamases and shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae (CRE). Synonyms: BOS-228; LYS-228. CAS No. 1810051-96-7. Molecular formula: C16H18N6O10S2. Mole weight: 518.47. | |
| Ancriviroc | Ancriviroc, an oximino-piperidino-piperidine-amide, is a CCR5 receptor antagonist. Uses: Ccr5 receptor antagonists. Synonyms: SCH-351125; SCH 351125; SCH351125; [4-[4-[C-(4-bromophenyl)-N-ethoxy-carbonimidoyl]-1-piperidyl]-4-methyl-1-piperidyl]-(2,4-dimethyl-1-oxido-pyridin-3-yl)methanone. Grade: ≥98%. CAS No. 370893-06-4. Molecular formula: C28H37BrN4O3. Mole weight: 557.52. | |
| Andarine | Andarine is a selective non-steroidal androgen receptor (AR) agonist with Ki of 4 nM, tissue-selective for anabolic organs. Synonyms: GTx-007; GTx007; GTx 007; S-4; S4; S 4; Andarine. Grade: >98%. CAS No. 401900-40-1. Molecular formula: C19H18F3N3O6. Mole weight: 441.36. | |
| Androgen receptor antagonist 1 | Androgen receptor antagonist 1 is an orally available full androgen receptor antagonist (IC50 = 59 nM). It can be used in the synthesis of PROTAC AR degraders, which results in 24% and 47% AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively. Synonyms: Androgen receptor antagonist 1; 1338812-36-4; CHEMBL1916251; SCHEMBL17941138; SCHEMBL17947423; BDBM50356995; AKOS040732433; MS-27273; HY-130992; CS-0120091; N-[3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-1-(2-hydroxyethyl)pyrazole-4-carboxamide. Grade: 99%. CAS No. 1338812-36-4. Molecular formula: C21H25ClN4O3. Mole weight: 416.90. | |
| Andrograpanin | Andrograpanin is a bioactive compound from Andrographis paniculata with anti-inflammatory and anti-infectious properties. Synonyms: 3,14-Dideoxyandrographolide; 3-[2-[(1R,4aS,5R,8aS)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone. CAS No. 82209-74-3. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| Androstane-3a,17b-diol 3-O-b-D-glucuronide | Androstane-3a,17b-diol 3-O-b-D-glucuronide is a pivotal compound in the biomedical field assuming a fundamental function in the exploration of the metabolic processes, pharmacokinetics and therapeutic impacting of androstenediol as well as comparable steroids. Synonyms: androstanediol-17g; 5alpha-androstane-3alpha,17beta-diol 17-glucuronide; 5alpha-androstane-3alpha,17beta-diol 17-glucuronoside; 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronic acid; 3alpha-hydroxy-5alpha-androstan-17beta-yl beta-D-glucopyranosiduronic acid; (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl beta-D-glucopyranosiduronic acid; androstane-3,17-diol 17-glucuronide ; Androstane- 3alpha,17beta-diol glucuronide. CAS No. 148616-25-5. Molecular formula: C25H40O8. Mole weight: 468.6. | |
| Anecortave Acetate | Anecortave is a novel angiogenesis inhibitor. It can be used for the treatment of the exudative (wet) form of age-related macular degeneration. Anecortave possesses no glucocorticoid activity. Synonyms: Anecortave Acetate ; Anecortave; Al 3789; NSC 15475; NSC 24345; Retaane; Hydrocortisone Acetate EP Impurity E; [2-[(8R,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate. Grade: >95%. CAS No. 7753-60-8. Molecular formula: C23H30O5. Mole weight: 386.49. | |
| Anecortave Impurity 4 | An impurity of Anecortave. Synonyms: 9-Bromo-11,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate. Grade: > 95%. CAS No. 50733-54-5. Molecular formula: C23H31BrO6. Mole weight: 483.4. | |
| A-Neu5Ac-PEG3-azide | A-Neu5Ac-PEG3-azide is a PEGylated glycoside that can be used as a ligand for click chemistry. Synonyms: α-Neu5Ac-PEG3-azide; alpha-Neu5Ac-PEG3-azide; α-NeuAc-PEG3-Azide; α-L-Neu5Ac-PEG3-N3; α-L-NeuAc-PEG3-N3; α-NeuAc-PEG3-N3; N-acetylneuraminyl-PEG3-Azide; Sialyl-PEG3-Azide; NANA-PEG3-N3; 2-{2-[2-azidoethoxy]ethoxy}ethyl 5-(acetylamino)-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid; (8-Azido-3,6-dioxaoctyl) 5-(acetylamino)-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid. Molecular formula: C17H30N4O11. Mole weight: 466.44. | |
| Angiopeptin TFA | Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26?nM and 6.92?nM, respectively. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Synonyms: Angiopeptin (TFA); HY-P2090A; MS-32113; CS-0213957; 2478421-60-0. Grade: 99%. CAS No. 2478421-60-0. Molecular formula: C58H73F6N11O14S2. Mole weight: 1326.39. | |
| Angiotensin 1/2 (5-7) acetate | The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I is hydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. Molecular formula: C19H31N5O6. Mole weight: 425.49. | |
| Angiotensin 1/2 + A (2-8) Acetate | Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. Molecular formula: C51H75N13O12. Mole weight: 1062.22. | |
| Angiotensin (1-7) (acetate) | Angiotensin (1-7) (acetate) is an angiotensin I metabolite. Angiotensin (1-7) (acetate) inhibits purified canine ACE activity (IC50 = 0.65 μM). Angiotensin (1-7) (acetate) acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin (1-7) (acetate) blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Synonyms: 5-L-isoleucine-1-7-angiotensin II; Angiotensin Fragment 1-7 (acetate). Grade: 98%. Molecular formula: C43H66N12O13. Mole weight: 959.06. | |
| Angiotensin Fragment 1-7 acetate | Angiotensin Fragment 1-7 is a major active component of the renin-angiotensin system (RAS), produced from cleavage of Ang II by angiotensin-converting-enzyme type 2 (ACE2). Angiotensin 1-7 inhibits purified canine ACE activity with IC50 of 0.65 μM. This peptide can be generated by the action of ACE2, a homolog of ACE, on angiotensin II or by the action of neprilysin on angiotensin I. It has been studied in the context of ameliorating the symptoms of metabolic syndrome. Synonyms: 5-L-isoleucine-1-7-angiotensin II; Ang-(1-7). Grade: ≥95%. Molecular formula: C41H62N12O11·xC2H4O2. Mole weight: 899. | |
| Angiotensin I (human, rat, mouse) trifluoroacetate salt | Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grade: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48. | |
| Angiotensin II | Angiotensin II is a Vasoconstrictor that plays an endocrine role in the regulation of blood pressure, fluid and electrolyte homeostasis. Synonyms: Hypertensin; Human angiotensin II; Ang II; Asp-Arg-Val-Tyr-X-His-Pro-Phe; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-X-L-histidyl-L-prolyl-L-phenylalanine; 1-8-Angiotensin I; Angiotensin 2; Angiotensin AT2; MeSH ID: D000804. CAS No. 11128-99-7. | |
| Angiotensin II (3-8), human TFA | Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity. Synonyms: 5-L-isoleucine-3-8-angiotensin II, trifluoroacetate salt. Grade: 99%. Molecular formula: C42H55F3N8O10. Mole weight: 888.93. | |
| Angiotensin II 5-valine TFA | Angiotensin II 5-valine is an agonist of angiotensin receptor. Synonyms: Valine angiotensin II TFA; 5-L-Valine angiotensin II TFA. Molecular formula: C51H70F3N13O14. Mole weight: 1146.18. | |
| Angiotensin II human TFA | Angiotensin II human TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA. Grade: 99%. Molecular formula: C52H72F3N13O14. Mole weight: 1160.20. | |
| Angiotensin I/II (1-6) (TFA) | Angiotensin I/II (1-6) TFA is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I is hydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. Synonyms: Angiotensin I/II (1-6) (TFA); HY-P1829A; MS-31710; CS-0167697. Grade: 98%. Molecular formula: C38H56F3N11O12. Mole weight: 915.91. | |
| Angiotensin III TFA | Angiotensin III TFA is an angiotensin 1 (AT1) and AT2 receptor agonist. Synonyms: Angiotensin III, human, mouse (TFA); ANGIOTENSIN III TFA; HY-P1540A; MS-31893; CS-0614991; F84729; 2938960-55-3. Grade: 99%. Molecular formula: C48H67N12O11F3. Mole weight: 1045.13. | |
| Angoline | Angoline is a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Grade: 98%. CAS No. 21080-31-9. Molecular formula: C22H21NO5. Mole weight: 379.41. | |
| Angoline hydrochloride | STAT3 signaling pathway is an important target for human cancer therapy. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation. Synonyms: Angoline (hydrochloride). CAS No. 1071676-04-4. Molecular formula: C22H22ClNO5. Mole weight: 415.87. | |
| Anguizole | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. Synonyms: Anguizole|442666-98-0|7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|CS-0558|CHEMBL2170006|SCHEMBL14366829|DTXSID30359937|ZINC720413|BCP21132|Anguizole,CAS:442666-98-0|AKOS025149511|NCGC00379046-01|HY-13321|A924203|7-(Chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|7-[chloro(difluoro)methyl]-5-(2-furyl)-N-(2-thienylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|7-[chloro(difluoro)methyl]-5-furan-2-yl-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2 carboxamide. Grade: >98%. CAS No. 442666-98-0. Molecular formula: C17H11ClF2N4O2S. Mole weight: 408.81. | |
| Anhydro-4-azido-5,6,8-tri-O-benzyl-1,2,4-trideoxy-D-glycero-D-gulo-oct-1-ynitol | Anhydro-4-azido-5,6,8-tri-O-benzyl-1,2,4-trideoxy-D-glycero-D-gulo-oct-1-ynitol is a fascinating biomedical compound boasting immense potential in studying diverse diseases such as viral infections and cancers. Synonyms: 2-Azido-3,4,6-tri-O-benzyl-1,2-dideoxy-1-ethynyl-b-D-glucopyranose. CAS No. 443916-29-8. Molecular formula: C29H29N3O4. Mole weight: 483.56. | |
| Anhydro abiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. Grade: 95%. CAS No. 154229-20-6. Molecular formula: C24H29N. Mole weight: 331.49. | |
| Anhydro Galantamine | Anhydro Galanthamine is an impurity of Galanthamine. Synonyms: (4aS,8aS)-9,10,11,12-Tetrahydro-3-Methoxy-11-Methyl-4aH-benzofuro[3a,3,2-ef][2]benzazepine; R 116937; TetrahydrogalantaMine; GalantaMine impurity D. Grade: > 95%. CAS No. 664995-65-7. Molecular formula: C17H19NO2. Mole weight: 269.35. | |
| Anhydrohexitol G | Anhydrohexitol G is an Intriguing biomedical compound assuming a remarkable standing in research of cancerous cells, with a keen focus on breast and prostate malignancies. Its exceptional attributes grant it the power to impede tumor proliferation while fostering apoptosis. Synonyms: Anhydrohexitol guanine; 1,5-Anhydro-2-(guanin-9-yl)-2,3-dideoxy-D-arabinohexitol. CAS No. 149312-06-1. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
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