MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MMP-7-IN-2 | MMP-7-IN-2 is a potent and selective inhibitor of MMP7 with an IC50 value of 16 nM. MMP-7-IN-2 can be used for the research of diseases such as cancer and fibrosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2848717-49-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-153563. |  |
| MMP-7-IN-3 | MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2865097-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-156430. | |
| MMP-8 inhibitor-1 | MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MMP8-I. CAS No. 236403-25-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128133. | |
| MMP-9-IN-1 | MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 502887-71-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135232. | |
| MMP-9/MMP-13 Inhibitor I | MMP-9/MMP-13 Inhibitor I is a potent MMP-9 and MMP-13 inhibitor with IC50s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 204140-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-128026. | |
| MMP Inhibitor II | MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 203915-59-7. Pack Sizes: 1 mg. Product ID: HY-119423. | |
| MMPIP hydrochloride | MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1215566-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103111. | |
| MMRi62 | MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutation characteristics of KRAS and TP53.12[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352693-80-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148409. | |
| MMRi64 | MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 430458-66-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123950. | |
| MMV009085 | MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent. MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 298217-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-153612. | |
| MMV019313 | MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 μM. MMV019313 has activity against P. falciparum (Parasite)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902630-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113752. | |
| MMV688845 | MMV688845 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-GSK1729177A. CAS No. 2208962-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148478. | |
| MN551 | MN551 is a potent inhibitor of cysteine-directed electrophilic covalent that plays important roles in the biology of SOCS2 and its CRL5 complex, and as E3 ligase handles in proteolysis targeting chimera (PROTACs) to induce targeted protein degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3044099-90-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-156395. | |
| MN58b | MN58b is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. MN58b reduces cell growth through the induction of apoptosis, and also has antitumoral activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 203192-01-2. Pack Sizes: 1 mg. Product ID: HY-108431. | |
| MNI-caged-L-glutamate | MNI-caged-L-glutamate is an inert photolabile glutamate precursor. MNI-caged-L-glutamate does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate can be used for research on neurotransmitters[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 295325-62-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107520. | |
| Mn(II) protoporphyrin IX | Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21393-64-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136476A. | |
| MNK inhibitor 9 | MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 μM and 0.003 μM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1889336-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124638. | |
| MnTBAP chloride | MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55266-18-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126397. | |
| Mobocertinib | Mobocertinib (TAK-788) is an orally active and irreversible EGFR/HER2 inhibitor. Mobocertinib potently inhibits oncogenic variants containing activating EGFRex20ins mutations with selectivity over wild-type EGFR. Mobocertinib can be used in NSCLC research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-788; AP32788. CAS No. 1847461-43-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-135815. | |
| MOCAc-PLGL(Dpa)AR | MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer[1][2][3].\n. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. CAS No. 140430-53-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-131498. | |
| Mocertatug | Mocertatug (GSK5733584 antibody) is a humanized IgG1κ antibody targeting B7-H4/VTCN1. Mocertatug can be used to construct ADCs, such as Mocertatug Rezetecan (HY-185280)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK5733584 antibody; HS-20089 antibody; hu2F7. CAS No. 3042847-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991703. | |
| Mocertatug rezetecan | Mocertatug rezetecan (HS-20089; GSK5733584) is an antibody-drug conjugate (ADC) targeting B7-H4. Mocertatug rezetecan exhibits activity against platinum-resistant ovarian cancer. Mocertatug rezetecan is used for the research of advanced solid tumors, especially ovarian cancer and triple-negative breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HS-20089; GSK5733584. CAS No. 3042848-25-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-185280. | |
| Mocetinostat | Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively. Mocetinostat shows no inhibition on HDAC4, HDAC5, HDAC6, HDAC7, or HDAC8. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MGCD0103. CAS No. 726169-73-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12164. | |
| Moclobemide | Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro111163. CAS No. 71320-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0534. | |
| Mocravimod | Mocravimod (KRP-203 free base) is a sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal required by T cells to egress from lymph nodes and other lymphoid organs. Mocravimod preferentially binds to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. Mocravimod significantly lowered the concentration of reactive oxygen species (ROS), prevented mitochondrial permeability transition pore opening, boosted mitochondrial membrane potential (MMP), and increased phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3. Mocravimod retains T cell effector function. Mocravimod can be used for the study of acute myelogenous leukemia, diabetes and Myocardial Ischemia-Reperfusion Injury (MIRI)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KRP-203 free base. CAS No. 509092-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109038. | |
| Mocravimod hydrochloride | Mocravimod (hydrochloride) is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal required by T cells to egress from lymph nodes and other lymphoid organs. Mocravimod (hydrochloride) preferentially binds to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. Mocravimod (hydrochloride) significantly lowered the concentration of reactive oxygen species (ROS), prevented mitochondrial permeability transition pore opening, boosted mitochondrial membrane potential (MMP), and increased phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3. Mocravimod (hydrochloride) retains T cell effector function. Mocravimod (hydrochloride) can be used for the study of acute myelogenous leukemia, diabetes and Myocardial Ischemia-Reperfusion Injury (MIRI)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KRP-203. CAS No. 509088-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13660. | |
| Modakafusp alfa | Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-573. CAS No. 2254522-19-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99744. | |
| Modoflaner | Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1331922-53-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137445. | |
| Modotuximab | Modotuximab (DS 1024) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab binds non-overlapping epitopes on domain III of EGFR, a domain that is intact in EGFRvIII. Modotuximab has antitumor activity in vivo[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS 1024; Zatuximab. CAS No. 1310460-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99306. | |
| Modzatinib | Modzatinib (ITK kinase-IN-1) is an oral active, selective, covalent ITK/JAK3 dual-target inhibitor with IC50 values of 8 nM and 23 nM, respectively. Modzatinib exhibits anti-inflammatory activity and can be used in the research of autoimmune and inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITK kinase-IN-1. CAS No. 2411407-25-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-174280. | |
| Moenomycin complex | Moenomycin complex is a class of antibacterial agents and PBP inhibitors, with Kd values ranging from 94 nM to 1690 nM against various bacterial PBPs. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs). Moenomycin complex is used in the research of bacterial infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11015-37-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-126387. | |
| MOG(35-55) amide, mouse, rat | MOG (35-55) amide, mouse, rat the terminal amidation form of the 35-55 fragment of the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide (MOG (35-55) (HY-P1240)). MOG(35-55) amide, mouse, rat can be used for experimental autoimmune encephalomyelitis (EAE) modeling[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2022956-48-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3719. | |
| MOG (35-55) mouse, rat | MOG (35-55) mouse, rat (Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat) is a minor component of CNS myelin. MOG (35-55) mouse, rat has encephalitogenic activity and induces T cell proliferative. MOG (35-55) mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. MOG (35-55) mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. MOG (35-55) mouse, rat (MOG (35-55)) can be used for experimental autoimmune encephalomyelitis (EAE) modeling[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat. CAS No. 149635-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1240. | |
| Mogamulizumab | Mogamulizumab (KW-0761) is a recombinant anti-CCR4 monoclonal antibody (MAb). Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KW-0761. CAS No. 1159266-37-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99253. | |
| Mogrol | Mogrol is a biometabolite of mogrosides, and acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB activation and activating AMPK signaling. Uses: Scientific research. Category: Signaling pathways. CAS No. 88930-15-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2312. | |
| Mogroside I E1 | Mogroside I E1 is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88901-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6853. | |
| Mogroside II-?A | Mogroside II-A is a natural product isolated from Siraitia grosvenorii[1]. Uses: Scientific research. Category: Natural products. CAS No. 1613527-65-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6915. | |
| Mogroside IV-E | Mogroside IV-E, a triterpenoid glycoside, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1]. Uses: Scientific research. Category: Natural products. CAS No. 88915-64-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2456. | |
| MO-I-1100 | MO-I-1100 is an inhibitor of ASPH (Aspartyl-(Asparaginyl)-β-hydroxylase) enzymatic activity. MO-I-1100 suppresses HCC cell migration, invasion and anchorage independent growth. MO-I-1100 shows antitumor effects through inhibiting Notch signaling cascade in HCC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1585217-40-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-164410. | |
| Molibresib | Molibresib (I-BET762; GSK525762) is a BET bromodomain inhibitor with IC50 of 32.5-42.5 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: I-BET762; GSK525762; GSK525762A. CAS No. 1260907-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13032. | |
| Molidustat | Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 85-3934. CAS No. 1154028-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-12654. | |
| Mollugin | Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55481-88-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0316. | |
| Molnupiravir | Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EIDD-2801; MK-4482. CAS No. 2492423-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-135853. | |
| Momelotinib | Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CYT387. CAS No. 1056634-68-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-10961. | |
| Momelotinib sulfate | Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: CYT387 sulfate salt. CAS No. 1056636-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10962. | |
| Mometasone furoate | Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch32088. CAS No. 83919-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13693. | |
| Mometasone (Standard) | Mometasone (Standard) is the analytical standard of Mometasone. This product is intended for research and analytical applications. Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 105102-22-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0629R. | |
| MOMIPP | MOMIPP, a macropinocytosis inducer, is a PIKfyve inhibitor. MOMIPP penetrates the blood-brain barrier (BBB)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1363421-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119624. | |
| Momordin Ic | Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96990-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0330. | |
| Monalizumab | Monalizumab (IPH2201) is an immune checkpoint inhibitor targeting Natural Killer Group 2A (NKG2A). Monalizumab, a humanized anti-NKG2A blocking mAb, increases IFN-γ production, thereby promoting NK cell effector functions. Monalizumab can be used for the research of head and neck squamous cell carcinoma (HNSCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPH2201. CAS No. 1228763-95-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99032. | |
| Monascin | Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21516-68-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6641. | |
| Monascorubramine | Monascorubramine is a microbial colorant. Monascorubramine is capable of producing by the Monascus, which is from the bacteria Talaromyces. Under the condition of different pH value, the hue and chromaticity value of the colorant are also different[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3627-51-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11071. | |
| Monascuspiloin | Monascuspiloin (Monascinol) exhibits anti-androgenic activity with an IC50 of 7 μM. Monascuspiloin inhibits viability of PC-3 and LNCaP with IC50 of 45 and 47 μM. Monascuspiloin induces apoptosis in LNCaP through inhibition of Akt/mTOR signaling pathway, induces autophagy through activation AMPK signaling pathway and arrest cell cycle at G2/M phase in PC-3. Monascuspiloin exhibits antitumor efficacy in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monascinol. CAS No. 1011244-19-1. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N12124. | |
| Monastrol | Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Monastrol. CAS No. 329689-23-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101071A. | |
| Monensin | Monensin (Monensin A), an orally active antibiotic, is an ionophore that mediates Na+/H+ exchange. Monensin is a potent Wnt signaling inhibitor. Monensin causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monensin A. CAS No. 17090-79-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N4302. | |
| Monensin B | Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA[1]. Uses: Scientific research. Category: Natural products. CAS No. 30485-16-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4301. | |
| Monensin sodium | Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na+/H+ exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monensin A sodium. CAS No. 22373-78-0. Pack Sizes: 10 mM * 1 mL in Ethanol; 100 mg. Product ID: HY-N0150. | |
| Monepantel | Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor. Monepantel triggers autophagy through the deactivation of mTOR/p70S6K signalling pathway. Monepantel is a positive allosteric modulator of a nematode-specific clade of nAChR subunits. Monepantel can be used for the study of amyotrophic lateral sclerosis (ALS) and ovarian cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AAD1566; NUZ-001. CAS No. 887148-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14774. | |
| Mongersen sodium | Mongersen sodium is a specific and orally active SMAD7 antisense oligonucleotide. Mongersen sodium restores TGF-β1 activity leading to inhibition of inflammatory signals. Mongersen sodium can attenuate Crohn's disease-like experimental colitis in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GED-0301 sodium. CAS No. 1443994-98-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145721A. | |
| Moniliformin sodium salt | Moniliformin sodium salt is a potent mycotoxin isolate from Fusarium moniliforme. Uses: Scientific research. Category: Signaling pathways. CAS No. 71376-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101905. | |
| Monlunabant | Monlunabant ((S)-MRI-1891) is an orally active antagonist for cannabinoid receptor 1 (CB1), binds to hCB1 and hCB2 with Ki of 0.3 nM and 613 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-MRI-1891; INV-202. CAS No. 2712480-46-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153800. | |
| MONNA | MONNA is a potent transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with an IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1572936-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100613. | |
| Mono(2-ethyl-5-hydroxyhexyl) phthalate | Mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is a biomarker for human exposure to DEHP (HY-B1945). By activating the tryptophan-kynurenine-aryl hydrocarbon receptor (AhR) pathway, mono (2-ethyl-5-hydroxyhexyl) phthalate significantly increases the viability of primary uterine leiomyoma cells and reduces cell apoptosis. Mono (2-ethyl-5-hydroxyhexyl) phthalate correlates with decreased sperm DNA damage. Mono (2-ethyl-5-hydroxyhexyl) phthalate can be used in studies related to uterine leiomyoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEHHP. CAS No. 40321-99-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133677. | |
| Mono(2-ethyl-5-oxohexyl) phthalate | Mono (2-ethyl-5-oxohexyl) phthalate (5-oxo-MEHP) is an oxidative metabolite of Di (2-ethylhexyl) phthalate (DEHP). Mono (2-ethyl-5-oxohexyl) phthalate may protective sperm DNA damage. Di (2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-oxo-MEHP. CAS No. 40321-98-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-133676. | |
| Mono-(2-ethylhexyl) phthalate | Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEHP; Phthalic acid mono-2-ethylhexyl ester. CAS No. 4376-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W018392. | |
| Mono-(2-ethylhexyl) phthalate-d4 | Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEHP-d4; Phthalic acid mono-2-ethylhexyl ester-d4. CAS No. 1276197-22-8. Pack Sizes: 10 mg. Product ID: HY-W018392S. | |
| Monoamine oxidase, plasma | Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-66-5. Pack Sizes: 100 U. Product ID: HY-E70074. | |
| Monobehenin | Monobehenin, an bacterial biofilm formation inhibitor, has strong inhibitory activity toward bacterial biofilm formation of S. mutans, X. oryzae, and Y. enterocolitica in a strain specific manner[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 30233-64-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-20349. | |
| Monochlorobimane | Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chlorobimane, mBBr. CAS No. 76421-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101899. | |
| Monocrotaline | Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits OCT-1 and OCT-2 with IC50s of 36.8 μM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. [2][6][8]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Crotaline. CAS No. 315-22-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0750. | |
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