MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MTX-23 | MTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PROTAC AR-V7 degrader-2. CAS No. 2488296-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148771. |  |
| MTX-531 | MTX-531 is an oral drug that inhibits EGFR (with an IC50 of 14.7 nM) and PI3K (with IC50 values of 6.4, 233, 8.3, and 1.1 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ respectively), and it has anti-tumor effects. MTX-531 also acts as a weak agonist of PPARγ, with an IC50 of 2.5 μM, helping to alleviate hyperglycemia induced by PI3K inhibitors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2791417-66-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162713. | |
| MU1210 | MU1210 (compound 12f), a chemical probe, is an inhibitor of CDC-like kinases Clk1, Clk2, and Clk4 (with IC50 values of 8, 20, and 12 nM respectively), with IC50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: Cmax=1.24 μM, T1/2=58 minutes; no acute toxicity observed)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2275601-87-9. Pack Sizes: 5 mg. Product ID: HY-125290. | |
| MU1409 | MU1409 is an inhibitor of MRE11 nuclease with an IC50 of 12.1 μM. Additionally, MU1409 also inhibits FEN1 and EXO1, with IC50 values of 24.2 and 176.4 μM, respectively. MU1409 affects DNA repair in cells, preventing the degradation of stalled replication forks in BRCA2-deficient cells, making it a promising candidate for research on BRCA2 mutation-induced cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2379671-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170845. | |
| MU147 | MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer activity, which is lethal to Ehrlich ascites tumor cells both in vitro and in vivo. MU147 also eliminates the double-strand break repair mechanism dependent on the MRE11 nuclease activity without impairing the activation of ATM. MU147 also impairs the degradation of nascent strands of stalled replication FOX and selectively affects brca2-deficient cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2379405-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170844. | |
| MU1742 | MU1742 is a probe for CK1δ and CK1ε protein kinases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3095089-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-148251. | |
| Mubritinib | Mubritinib (TAK-165) is a potent and selective EGFR2/HER2 inhibitor with an IC50 of 6 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-165. CAS No. 366017-09-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13501. | |
| MUC5AC motif peptide | MUC5AC motif peptide is a 16-amino acid fragment of mucin 5. Uses: Scientific research. Category: Signaling pathways. CAS No. 244049-41-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0280. | |
| Mufemilast | Mufemilast (Heymay005) is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor (IC50 = 80-120 nM). Mufemilast modulates cytokines upregulated in Beh?ets syndrome (BS). Mufemilast displays a significant inhibitory effect on TNF-α, which is an important proinflammatory cytokine target in the disease process of psoriasis. Mufemilast can be studied in research for diseases such as rheumatoid arthritis, psoriasis and BS[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hemay005. CAS No. 1255909-03-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145583. | |
| Mulberroside A | Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.)[1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102841-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0619. | |
| mUNO | mUNO is a tumor-homing peptide (mUNO, sequence: "CSPGAK") that specifically binds to mouse CD206, targeting tumor-associated macrophages that express CD206/MRC1. mUNO can interact with human recombinant CD206[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2283322-63-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10894. | |
| Mupirocin | Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BRL-4910A; Pseudomonic acid. CAS No. 12650-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0958. | |
| Mupirocin lithium | Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BRL-4910A lithium; Pseudomonic acid lithium. CAS No. 73346-79-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W108875. | |
| Muramyl dipeptide | Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MDP. CAS No. 53678-77-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127090. | |
| Murepavadin TFA | Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: POL7080 TFA. CAS No. 3053070-05-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P1674A. | |
| MuRF1-IN-1 | MuRF1-IN-1 is an orally active MuRF1 inhibitor. MuRF1-IN-1 can inhibit the interaction between MuRF1 and titin as well as E3 ligase activity. MuRF1-IN-1 can alleviate skeletal muscle atrophy and dysfunction in cardiac cachexia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 445222-91-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129531. | |
| Murideoxycholic acid | Murideoxycholic acid is a 6 beta-hydroxylated bile acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 668-49-5. Pack Sizes: 1 mg. Product ID: HY-N0169B. | |
| Murlentamab | Murlentamab (3C23K; GM102) is a humanized anti-AMHRII antibody. AMHRII is the anti-Müllerian hormone receptor. Murlentama significantly promotes macrophage-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Murlentama stimulates pro-inflammatory and anti-tumor internal environment, recruits and activates T cells. Murlentama suppresses tumors growth by inducing naïve macrophage orientation and promoting tumor-associated macrophage (TAM) reprogramming[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3C23K; GM102. CAS No. 2058047-65-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99746. | |
| Muromonab | Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Muromanab-CD3. CAS No. 140608-64-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99152. | |
| MUS81-IN-1 | MUS81-IN-1 (compound 23) is a MUS81 inhibitor. MUS81-IN-1 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3082549-87-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163699. | |
| Muscle homing peptide M12 | Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2896181-32-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10646. | |
| Mussaenosidic acid | Mussaenosidic acid is an active product that can be extracted from Pedicularis kerneri Dalla Torre. Mussaenosidic acid shows weak antiglycation activity[1]. Uses: Scientific research. Category: Natural products. CAS No. 82451-22-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12580. | |
| Mutanolysin | Mutanolysin is a bacteriolytic agent. Mutanolysin is a muralytic enzyme that can prevent hepatic injury. Mutanolysin can digest the cell wall of S. mutans BHT and shows antibacterial activity. Mutanolysin reduces TNF-α production in isolated Kupffer cells stimulated with peptidoglycan-polysaccharide (PG-APS). Mutanolysin can be used for the researches of infection, inflammation and hepatic injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55466-22-3. Pack Sizes: 1 KU; 5 KU; 10 KU; 50 KU. Product ID: HY-P3023. | |
| Muvalaplin | Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) (Lp (a)) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a)formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3473329. CAS No. 2565656-70-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152857. | |
| Muzastotug | Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADG126. CAS No. 2750031-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990048. | |
| MW-150 | MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MW01-18-150SRM. CAS No. 1628502-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120111. | |
| MX1013 | MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC50 of 30 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CV1013; Z-VD-FMK. CAS No. 582316-00-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10397A. | |
| MX69 | MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. Uses: Scientific research. Category: Signaling pathways. CAS No. 1005264-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100892. | |
| MX69-102 | MX69-102 (compound MX69-102) is an MDM-2/p53 inhibitor, inducing MDM2 degradation, resulting in p53 activation and cancer cell apoptosis. MX69-102 shows effective inhibition on xenografted human MDM2-overexpressing ALL in SCID mice.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2925583-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169240. | |
| MY05 | MY05 selectively targets c-MYC in cells and disrupts MYC-MAX interaction. MY05 engages intracellular c-MYC, modulates c-MYC thermal stability, reduces c-MYC transcriptional targets, and possesses anticancer activity (TNBC, Triple-Negative Breast Cancer)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 667909-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-22445. | |
| MY10 | MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 reduces NF-κB p65 expression. MY10 activates tyrosine phosphorylation of c-Met. MY10 prevents the alcohol-induced downregulation of Ptprz1 and Alk expression. MY10 attenuates binge-like ethanol consumption and ethanol reward. MY10 can be used in the study of neurological and vascular diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2204270-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123856. | |
| MY-1B | MY-1B is a covalent inhibitor of the RNA Methyltransferase NSUN2 (IC50: 1.3 μM). MY-1B stereoselectively ligands active-site cysteine residues (C271) of NSUN2. MY-1B can stereoselectively and covalently bind to PSME1, disrupting the proteasome regulatory complex and downregulating the presentation of specific MHC-I subtypes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2929308-79-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158301. | |
| MY33-3 | MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2204280-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123966. | |
| MYC degrader 1 | MYC degrader 1 (compound A80.2HCl) is an orally available MYC molecular glues degrader with anti-tumor activity. MYC degrader 1 restores pRB1 protein activity and re-establishes sensitivity of MYC overexpressing cancer cells to CDK4/6 inhibitors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2946670-96-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162318. | |
| MYCi361 | MYCi361 (NUCC-0196361) is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NUCC-0196361. CAS No. 2289690-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129600. | |
| Myclobutanil (Standard) | Myclobutanil (Standard) is the analytical standard of Myclobutanil. This product is intended for research and analytical applications. Myclobutanil is a conazole class fungicide widely used as an agrichemical. Uses: Scientific research. Category: Signaling pathways. CAS No. 88671-89-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2148R. | |
| MYCMI-6 | MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6?μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50<0.5?μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC354961. CAS No. 681282-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124675. | |
| Mycophenolate Mofetil | Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RS 61443; TM-MMF. CAS No. 128794-94-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 1 g; 5 g. Product ID: HY-B0199. | |
| Mycophenolic acid | Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mycophenolate. CAS No. 24280-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0421. | |
| Mycophenolic acid-d3 | Mycophenolic acid-d3 (Mycophenolate-d3) is deuterium labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mycophenolate-d3. CAS No. 1185242-90-3. Pack Sizes: 1 mg. Product ID: HY-B0421S. | |
| Mycophenolic acid glucuronide | Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 31528-44-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-137301. | |
| Mycophenolic acid sodium | Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mycophenolate sodium. CAS No. 37415-62-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0421A. | |
| Mycro 3 | Mycro 3 is an orally active, potent and selective inhibitor of Myc-associated factor X (MAX) dimerization. Mycro 3 also inhibit DNA binding of c-Myc[1]. Mycro 3 could be used for the research of pancreatic cancer[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 944547-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100669. | |
| MyD88-IN-1 | MyD88-IN-1 (Compound c17) is an orally active MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2911609-80-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-149992. | |
| MyD88-IN-2 | MyD88-IN-2 (compound A5S) is a Myeloid differentiation primary response 88 (MyD88) inhibitor with the Kd of 15 μM. MyD88-IN-2 shows protective effects on LPS (HY-D1056)-induced and sepsis-induced ALI mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3067479-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170446. | |
| Myelin Basic Protein | Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MHP4-14. CAS No. 126768-94-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1821. | |
| Myelin Basic Protein (MBP) (68-82), guinea pig | Myelin Basic Protein (MBP) (68-82), guinea pig is a fragment of myelin basic protein (MBP). Uses: Scientific research. Category: Peptides. CAS No. 98474-59-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1048. | |
| Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse | Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse (MOG (40-54)) is a CD8-related self-antigenic epitope of the myelin oligodendrocyte glycoprotein (MOG) protein and is presented in association with H-2Db[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MOG (40-54). CAS No. 507233-87-6. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P5966. | |
| MYF-03-176 | MYF-03-176 is an orally active inhibitor of TEAD, and suppresses TEAD transcriptional activity with an IC50 of 11 nM. The IC50 values of MYF-03-176 for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively. MYF-03-176 inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2857937-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147136. | |
| MYF-03-69 | MYF-03-69 (TEAD-IN-3) is a covalent and irreversible TEAD inhibitor with IC50s of 385, 143, 558 and 173 nM for TEAD1, TEAD2, TEAD3 and TEAD4. MYF-03-69 disrupts YAP-TEAD association, suppresses TEAD transcriptional activity (IC50 = 56 nM) and up-regulates apoptosis gene BMF. MYF-03-69 selectively inhibits mesothelioma cancer cells with defective Hippo signaling. MYF-03-69 can be used for the study of malignant pleural mesothelioma (MPM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TEAD-IN-3. CAS No. 2416418-11-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147135. | |
| Myoferlin inhibitor 1 | Myoferlin inhibitor 1 is a compound that exhibits reversible, concentration-dependent binding to the myoferlin MYOF-C2D protein, with a KD of 0.094 μM. Myoferlin inhibitor 1 shows potent anti-invasion and anti-migration activities against different pancreatic cancer cells. Myoferlin inhibitor 1 inhibits pancreatic cancer metastasis through reversing mesenchymal transition (EMT), inhibiting the secretions of MMP1 and MMP2 and blocking the receptor tyrosine kinases. Myoferlin inhibitor 1 displays effective antimetastatic activities in pancreatic cancer in vitro and in vivo. Myoferlin inhibitor 1 can be used in research on preventing pancreatic cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2366279-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143657. | |
| Myoglobin | Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO2, MbO2 is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells[1]. Uses: Scientific research. Category: Biochemical assay reagents. CAS No. 100684-32-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-NP007. | |
| myo-Inositol trispyrophosphate hexasodium | myo-Inositol trispyrophosphate (ITPP) hexasodium is a salt form of inositol triphosphate (ITPP). myo-Inositol trispyrophosphate (ITPP) hexasodium is a membrane-permeant hemoglobin allosteric regulator. myo-Inositol trispyrophosphate (ITPP) hexasodium enhances the oxygen release capacity of red blood cells by reducing the affinity of hemoglobin to oxygen. myo-Inositol trispyrophosphate (ITPP) hexasodium can be used in the study of cardiovascular disease and cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITPP hexasodium. CAS No. 23103-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141510. | |
| MyoMed 205 | MyoMed 205 is an orally active muscle ring finger protein 1 (MuRF1) inhibitor. MyoMed-205 reduces ubiquitination and subsequent proteasomal degradation of muscle proteins by inhibiting MuRF1 activity. MyoMed 205 augments muscle performance, attenuates muscle weight loss and alleviates disease-induced weight loss. MyoMed 205 can be used for the research of cancer cachexia, type 2 diabetes mellitus, and heart failure with preserved ejection fraction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2614161-13-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164027. | |
| Myosin V-IN-1 | Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a Ki of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1259177-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152949. | |
| Myostatin inhibitory peptide 2 | Myostatin inhibitory peptide 2 (compd 2) is a myostatin inhibitor with a Kd of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1621169-52-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10476. | |
| Myrcene,75% (stabilized with BHT) | Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Myrcene. CAS No. 123-35-3. Pack Sizes: 1 g; 5 g. Product ID: HY-N0803. | |
| Myricanol | Myricanol is a diarylheptanoid and a Nampt activator. Myricanol exerts anti-inflammatory effects and alleviates glucocorticoid-induced muscle atrophy by increasing Sirtuin 1 (SIRT1) and PRDX5 activities while regulating inflammatory factors. Myricanol exhibits growth inhibition and induces apoptosis in human lung adenocarcinoma A549 cells. Myricanol promotes autophagy-mediated clearance of microtubule-associated protein tau to exert neuroprotective effects. Myricanol protects cardiovascular function by inhibiting PDGFRβ and NF-κB signaling pathways. Myricanol activates mitochondrial transcription factor A (TFAM) expression to exert anti-renal fibrosis effects. Myricanol improves insulin resistance through AMPK activation[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 33606-81-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3225. | |
| Myricetin | Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cannabiscetin. CAS No. 529-44-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15097. | |
| Myricetin 3'-glucoside | Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury[1]. Uses: Scientific research. Category: Natural products. CAS No. 520-14-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7905. | |
| Myricetin 3-O-galactoside | Myricetin 3-O-galactoside inhibits xanthine oxidase (XO) activity, lipid peroxidation and scavenges the free radical. Myricetin 3-O-galactoside inhibits lipid peroxidation with an IC50 of 160 μg/mL. Antioxidant activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15648-86-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3220. | |
| Myriocin | Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thermozymocidin; ISP-I. CAS No. 35891-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6798. | |
| Myristic acid | Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 544-63-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-N2041. | |
| Myristic acid-13C | Myristic acid-13C the 13C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. Uses: Scientific research. Category: Signaling pathways. CAS No. 57677-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N2041S2. | |
| Myristoleic acid | Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 544-64-9. Pack Sizes: 100 mg. Product ID: HY-113332. | |
| Myristoyl coenzyme A lithium | Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 187100-75-0. Pack Sizes: 1 mg. Product ID: HY-126833A. | |
| Myristoyl coenzyme A triammonium | Myristoyl coenzyme A triammonium (14:0 Coenzyme A) is a myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 14:0 Coenzyme A triammonium; S-Tetradecanoate-CoA triammonium; S-Tetradecanoate-coenzyme A triammonium. CAS No. 799812-85-4. Pack Sizes: 1 mg. Product ID: HY-126833B. | |
| Myristoyl ethanolamide | Myristoyl ethanolamide (N-Myristoylethanolamine) is a class of N-acylserinol compounds[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Myristoylethanolamine. CAS No. 142-58-5. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-119723. | |
| Myristoyl pentapeptide-17 acetate | Myristoyl pentapeptide-17 acetate can stimulate eyelash growth by stimulating keratin production. Myristoyl pentapeptide-17 acetate promotes the delivery of key ingredients in the serum, such as the growth factors and lysophosphatidic acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763588-80-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P0103A. | |
| Myt1-IN-1 | Myt1-IN-1 is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. Myt1-IN-1 has anticancer effects (WO2021195782A1; compound 132)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2719749-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145664. | |
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