MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Zosuquidar trihydrochloride | Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). Zosuquidar trihydrochloride shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RS 33295-198 trihydrochloride; LY-335979 trihydrochloride. CAS No. 167465-36-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50671. |  |
| Zosurabalpin | Zosurabalpin is a polypeptide antibiotic targeting LPS transporter (LptB2FGC complex), which can block the transport of LPS and lead to endotoxin accumulation in cells, and has shown excellent antibacterial activity against Carbapenem-resistant Acinetobacter baumanni (CRAB) [1] [2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Abx MCP; RG6006. CAS No. 2379336-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147429. | |
| Zotarolimus | Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12424. | |
| Zotatifin | Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex[1]. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM)[2]. Zotatifin induces cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: eFT226. CAS No. 2098191-53-6. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-112163. | |
| Zovegalisib | Zovegalisib (RLY-2608) is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity. Zovegalisib inhibits tumor growth in PIK3CA-mutant xenograft mice models with minimal impact on insulin[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RLY-2608. CAS No. 2733573-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153306. | |
| Zovodotin | MT-VC-ZD02044 is a cytotoxic and anti-mitotic agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MT-VC-ZD02044. CAS No. 1800462-96-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147006. | |
| Zovostotug | Zovostotug is a human CD163 (scavenger receptor cysteine-rich (SRCR) type 1 M130) mAb[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: OR-2805. CAS No. 2756228-84-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990087. | |
| Z-Phe-Ala-diazomethylketone | Z-Phe-Ala-diazomethylketone binds directly to Aβ42 monomers and small oligomers. Z-Phe-Ala-diazomethylketone inhibits the formation of Aβ42 dodecamers and inhibits Aβ42 fibril formation in the solution. Z-Phe-Ala-diazomethylketone has the potential for neurodegenerative disorders research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PADK. CAS No. 71732-53-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P4295. | |
| Z-Phe-Arg-pNA | Z-Phe-Arg-pNA is a substrate of Cathepsin L[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117761-01-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P4515. | |
| Z-Phe-Leu-Glu-pNA | Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 104634-10-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4516. | |
| Z-Phe-Tyr(tBu)-diazomethylketone | Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114014-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138208. | |
| (Z)-PUGNAc | (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 132489-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-108241. | |
| zr17-2 | zr17-2 is a cold inducible RNA-binding protein (CIRBP) agonist. zr17-2 has anti-inflammatory and anti-oxidant and can be used for the study of myocardial infarction. zr17-2 is a hypothermia mimetic molecule that reduces oxidative stress-induced retinal cell death[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263893-98-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125972. | |
| Z-Sar-OH | Z-Sar-OH is a Glycine (HY-Y0966) derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39608-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-W013517. | |
| (Z)-Semaxanib | (Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 μM and 8.17 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Z)-SU5416. CAS No. 194413-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-10332. | |
| ZSET1446 | ZSET1446 is a novel cognitive enhancer that significantly improves learning deficits in various types of Alzheimer disease (AD) models. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ST-101. CAS No. 887603-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11013. | |
| ZSTK474 | ZSTK474 is an ATP-competitive pan-class I PI3K inhibitor with IC50s of 16 nM, 44 nM, 4.6 nM and 49 nM for P&Lota;3Κα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 475110-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50847. | |
| ZT-12-037-01 | ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. ZT-12-037-01 is an ATP-competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC50 of 24 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2328073-61-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122866. | |
| ZT-1a | ZT-1a is a potent, non-ATP-competitive and selective SPAK inhibitor. ZT-1a inhibits SPAK activity with IC50s of 44.3, 35.0, 46.7 μM at ATP concentrations of 0.01, 0.1 and 1 mM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 212135-62-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-136532. | |
| (Z)-Thiothixene | (Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1. Uses: Scientific research. Category: Signaling pathways. CAS No. 3313-26-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108324. | |
| Z-Tyr-Lys-Arg-pNA | Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases[1]. Uses: Scientific research. Category: Peptides. CAS No. 108318-36-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4517. | |
| Zubotamig | Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gen1047. CAS No. 2640279-10-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990953. | |
| Zunsemetinib | Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATI-450; CDD-450. CAS No. 1640282-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-139553. | |
| Zurletrectinib | Zurletrectinib is a brain-penetrant, orally active TRK inhibitor (TRKA IC50 = 0.81 nM; TRKB IC50 = 0.145 nM; TRKC IC50 = 0.184 nM). Zurletrectinib exhibits stronger activity as a consequence of its augmented binding affinity for TRK kinases. Zurletrectinib exhibits higher activity against most TRK inhibitor resistance mutations (13 out of 18 mutations). Zurletrectinib can be used for the study of glioma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ICP-723. CAS No. 2403703-30-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148811. | |
| Z-VAD | Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit a variety of caspases including caspase-3, -6, -7, -8, -9, etc. (with a weaker inhibitory effect on caspase-2). Z-VAD can block apoptosis signaling pathways, induce autophagy and necrosis in tumor cells, and has anti-angiogenic activity. Z-VAD can enhance the sensitivity of breast cancer and lung cancer cells to radiotherapy in vitro and in vivo, and prolong the growth delay of tumor xenograft models. Z-VAD is well tolerated and is mainly used in research related to cancer radiosensitization and cell death pathway regulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 162852-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164388. | |
| Z-VAD-FMK | Z-VAD-FMK is a pan-caspase inhibitor and also an ICE-like protease inhibitor, which inhibits apoptosis by preventing the processing of CPP32 to its active form. Z-VAD-FMK sensitivity varies primarily due to differential expression of receptor-interacting protein 1 (RIP1). Z-VAD-FMK limits the cryopreservation-induced apoptosis by reducing caspase-3 activity of in vitro produced bovine embryos. Z-VAD-FMK is immunosuppressive in vitro and inhibits T cell proliferation without blocking the processing of caspase-8 and caspase-3. Z-VAD-FMK leads to a decrease in intracellular glutathione (GSH) with a concomitant increase in reactive oxygen species (ROS) levels in activated T cells. Z-VAD-FMK is due to oxidative stress via the depletion of GSH. Z-VAD-FMK can be used for the study of acute pancreatitis[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-VAD(OH)-FMK. CAS No. 161401-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16658B. | |
| Z-VAD(OMe)-FMK | Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor[1]. Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-Val-Ala-Asp(OMe)-FMK. CAS No. 187389-52-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16658. | |
| Z-Val-Val-Arg-AMC | Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 124485-41-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-137367. | |
| Z-VDVAD-FMK | Z-VDVAD-FMK is a special inhibitor of caspase-2. Z-VDVAD-FMK produces a reduction in Lovastatin-induced apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-VD(OMe)VAD(OMe)-FMK. CAS No. 210344-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1008. | |
| Z-VEID-FMK | Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-VE(OMe)ID(OMe)-FMK. CAS No. 210344-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1007. | |
| Z-VRPR-FMK | Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1381885-28-4. Pack Sizes: 100 μg; 200 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-120231. | |
| ZW-1226 | ZW-1226 is a dual Tyrosyl DNA phosphodiesterase 2 (TDP2) and Multidrug resistance-associated protein 1 (MRP1) inhibitor with IC50 values of 0.2 and 0.5 μM, respectively. ZW-1226 exhibits selectivity over other ABC transporters. ZW-1226 elevates intracellular GSH levels, and reverses MRP1-mediated drug resistance. ZW-1226 can be used for the research of leukemia, non-small-cell lung cancer, and multidrug resistant small-cell lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2351940-23-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162753. | |
| ZW4864 free base | ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2632259-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132300A. | |
| Z-WEHD-FMK | Z-WEHD-FMK is a potent, cell-permeable and irreversible caspase-1/5 inhibitor. Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM). Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-WE(OMe)HD(OMe)-FMK. CAS No. 210345-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0111. | |
| ZXH-1-161 | ZXH-1-161 is a potent CRBN modulator that selectively induces the degradation of GSPT1 in a CRBN-dependent manner. ZXH-1-161 can inhibit the proliferation of multiple myeloma cells and exhibits antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2407654-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147158. | |
| ZXH-3-26 | ZXH-3-26 is a PROTAC connected by ligands for Cereblon and BRD4 with a DC50/5h of 5 nM. The DC50/5h refers to half-maximal degradation after 5 hours of treatment of ~ 5 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2243076-67-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122826. | |
| ZXH-4-130 | ZXH-4-130 is a highly potent and selective degrader of CRBN. ZXH-4-130 is a CRBN-VHL compound (hetero-PROTAC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2711006-66-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-132857. | |
| ZY-444 | ZY-444 is an anti-cancer agent, targeting pyruvate carboxylase (PC). ZY-444 suppresses the Wnt/β-catenin/Snail signaling pathway by blocking nuclear translocation of β-catenin. ZY-444 selectively inhibits proliferation, migration, and invasion and induces apoptosis in cancer cells. ZY-444 exhibits potent anti-tumor in cancer mouse models. ZY-444 can be used for the study of breast cancer, lung cancer (NSCLC), prostate cancer and iodine-refractory thyroid cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802650-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142870. | |
| ZYF0033 | ZYF0033 is an orally active inhibitor of the hematopoietic progenitor cell kinase HPK1 with an IC50 of less than 10 nM based on the phosphorylation inhibition of MBP protein. ZYF0033 promotes anti-cancer immune responses and reduces phosphorylation of SLP76 (serine 376). ZYF0033 inhibits tumor growth in the 4T-1 syngeneic mouse model and leads to increased intratumoral infiltration of DCs, NK cells, and CD107a+CD8+ T cells, but not T cells, PD-1+CD8+ T cells, TIM-3+CD8+ Infiltration of T cells and LAG3+CD8+ T cells was reduced[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HPK1-IN-22. CAS No. 2380300-79-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144088. | |
| Zylofuramine | Zylofuramine is a psychomotor stimulant. Zylofuramine can be used in the research related to appetite suppressants and Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3563-92-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122477. | |
| Zymosan A | Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Zymosan A from Saccharomyces cerevisiae. CAS No. 58856-93-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-W250113. | |
| Zymosan (ZM), 95% | Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9010-72-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-159069. | |
| Zymostenol | Zymostenol (5a-Cholest-8-en-3b-ol) is a late-stage precursor in the biosynthesis of cholesterol. Zymostenol is a RORγ agonist (EC50: 1 μM)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5a-Cholest-8-en-3b-ol. CAS No. 566-97-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113345. | |
| Zymosterol | Zymosterol is a Cholesterol (HY-N0322) biosynthesis metabolite. Zymosterol, a precursor of Cholesterol, is found mostly in the plasma membrane. Zymosterol circulates within the cell[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 128-33-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114297. | |
| Z-YVAD-AFC | Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1[1]. Uses: Scientific research. Category: Peptides. CAS No. 201608-13-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P4429. | |
| Z-YVAD-FMK | Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210344-97-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1009. | |
| ZYZ-488 | ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor. ZYZ-488 inhibits the activation of binding protein procaspase-9 and procaspase-3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1470302-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100472. | |
| ZZM-1220 | ZZM-1220 is a histone lysine methyltransferase G9a/GLP covalent inhibitor with IC50s of of 458 nM and 924 nM, respectively. ZZM-1220 inhibits H3K9me2 in cells and significantly induces apoptosis of triple-negative breast cancer (TNBC) cells and blocks the cell cycle in the G2/M phase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053365-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156285. | |
| ZZW-115 | ZZW-115 is a potent NUPR1 inhibitor, with a Kd of 2.1 μM. ZZW-115 induces tumor cell death by necroptosis and apoptosis. Anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 801991-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-111838. | |
| ZZW-115 hydrochloride | ZZW-115 hydrochloride is a potent NUPR1 inhibitor, with a Kd of 2.1 μM. ZZW-115 hydrochloride induces tumor cell death by necroptosis and apoptosis. Anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10122-45-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111838A. | |
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