MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MYX1715 | MYX1715 is an inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 with IC50 values of 44 nM and 9 nM. MYX1715 exhibits antitumor efficacy against neuroblastoma and gastric cancer in mouse models. MYX1715 can be used as ADC toxin[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMP1320. CAS No. 2445448-66-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164285. |  |
| Myxothiazol | Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76706-55-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-112177. | |
| MZ 1 | MZ 1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1797406-69-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107425. | |
| MZ-101 | MZ-101 (GYS1-IN-2) is an orally active, potent and selective small-molecule glycogen synthase 1 (GYS1) inhibitor with with an IC50 value of 0.041 μM. MZ-101 reduces glycogen concentrations in cells and in mice. MZ-101 can used to study GYS1 -mediated Pompe disease and other glycogen storage diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GYS1-IN-2. CAS No. 2839908-40-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157646. | |
| MZP-54 | MZP-54 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a Kd of 4 nM for Brd4BD2. Uses: Scientific research. Category: Signaling pathways. CAS No. 2010159-47-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112376. | |
| MZP-55 | MZP-55 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a Kd of 8 nM for Brd4BD2. Uses: Scientific research. Category: Signaling pathways. CAS No. 2010159-48-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112377. | |
| N106 | N106 is a first-in-class sarcoplasmic reticulum calcium ATPase (SERCA2a) SUMOylation activator. N106 directly activates the SUMO-activating enzyme, E1 ligase. N106 can be used for heart failure research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862974-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110273. | |
| N1-Acetylspermidine hydrochloride | N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamines and a substrate for polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride can promote Apoptosis in combination with Procyanidins. N1-Acetylspermidine hydrochloride has a certain cleavage efficiency at apurinic sites of DNA. N1-Acetylspermidine hydrochloride can be used in colorectal cancer research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34450-16-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113056A. | |
| N1-Acetylspermine trihydrochloride | N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77928-70-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-113200A. | |
| N1-Methylpseudouridine | N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Methylpseudouridine; N1-methyl-pseudouridine. CAS No. 13860-38-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112582. | |
| N1-Methylpseudouridine-5-triphosphate solution (100 mM) | N1-Methylpseudouridine-5-triphosphate (1-Methylpseudouridine-5-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Methylpseudouridine-5-triphosphate. CAS No. 1428903-59-6. Pack Sizes: 100 μL; 200 μL; 500 μL; 1 mL. Product ID: HY-112582A. | |
| N1-Methylpseudouridine-5-triphosphate trisodium solution (100 mM) | N1-Methylpseudouridine-5-triphosphate (1-Methylpseudouridine-5-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5-triphosphate (1-Methylpseudouridine-5-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Methylpseudouridine-5-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium. CAS No. 3056945-59-3. Pack Sizes: 5.64 mg (100 mM * 100 μL in water); 11.28 mg (100 mM * 200 μL in water); 28.21 mg (100 mM * 500 μL in water); 56.41 mg (100 mM * 1 mL in water). Product ID: HY-112582C. | |
| N1,N11-Diethylnorspermine tetrahydrochloride | N1, N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) is a potent anticancer agent. N1,N11-Diethylnorspermine tetrahydrochloride activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine tetrahydrochloride induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diethylnorspermine tetrahydrochloride; DENSPM tetrahydrochloride; BENSPM tetrahydrochloride. CAS No. 156886-85-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13610A. | |
| N1,N12-Diacetylspermine dihydrochloride | N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DiAcSpm dihydrochloride. CAS No. 77928-71-3. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113374A. | |
| N1,N5-Bis-boc-spermidine | N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. Uses: Scientific research. Category: Signaling pathways. CAS No. 68076-39-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-42222. | |
| N1,N8-Diacetylspermidine | N1,N8-Diacetylspermidine is a polyamines in the human urine[1]. N1,N8-Diacetylspermidine is useful as prognostic indicators after treatment and during follow-up examination of cancer patients[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 82414-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-129912. | |
| N-1-Naphthylphthalamic acid | N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation[1][1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alanap 1. CAS No. 132-66-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-116425. | |
| N-1-Naphthylphthalamic acid (Standard) | N-1-Naphthylphthalamic acid (Standard) is the analytical standard of N-1-Naphthylphthalamic acid. This product is intended for research and analytical applications. N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation[1][1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alanap 1 (Standard). CAS No. 132-66-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116425R. | |
| N-(2,4-Dinitrophenyl)glycine | N-(2,4-Dinitrophenyl)glycine is a Glycine (HY-Y0966) derivative[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC37410. CAS No. 1084-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-118174. | |
| N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine | N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine is a lysine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118584-90-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g. Product ID: HY-W053701. | |
| N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-N2-methyl-L-lysine | N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-N2-methyl-L-lysine is a lysine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 197632-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W036333. | |
| N-(2-Aminoethyl)maleimide hydrochloride | N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a selective covalent binding agent for thiol groups (RSGs), covalently binding to thiols via an irreversible thioether bond to prepare MMP-2-sensitive nanosystems. Under near-neutral conditions, the maleimide group in N-(2-Aminoethyl)maleimide hydrochloride binds to thiol groups via a nucleophilic addition reaction, and can be used to modify polymers or biological interfaces, enhancing mucosal adhesion and regulating the surface charge of biological interfaces. N-(2-Aminoethyl)maleimide hydrochloride can optimize the adhesion performance of drug delivery carriers and cell interactions with biological interfaces, and is applied in transmucosal drug delivery systems (such as drug carriers for oral and bladder sites) and biomaterial surface engineering research, providing support for tissue implantation, regeneration, and related drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Maleimidoethylamine hydrochloride. CAS No. 134272-64-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W068119A. | |
| N-(2-Hydroxyethyl)maleimide | N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1585-90-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W017588. | |
| N2-Methylguanosine | N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-77-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111647. | |
| N2,N2-Dimethylguanosine | N2,N2-Dimethylguanosine is a methylated modified nucleoside present in RNA and serves as a structural modification component of tRNA. N2,N2-Dimethylguanosine inhibits reverse transcriptase-mediated cDNA synthesis and is one of the key modifications affecting sequencing efficiency in high-throughput RNA sequencing. N2,N2-Dimethylguanosine can be selectively demethylated at one methyl group by AlkB mutant enzymes (such as D135S/L118V) and converted to N2-methylguanosine, thereby reducing the inhibition of reverse transcription[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-67-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113137. | |
| N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly | N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10-4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAPGG. CAS No. 64967-39-1. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W010991. | |
| N33-TEG-COOH | N33-TEG-COOH (N3-TEG-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N33-TEG-COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N3-TEG-COOH; 14-Azido-3,6,9,12-tetraoxatetradecanoic acid. CAS No. 201467-81-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-108370. | |
| N3Ac-OPhOMe | N3Ac-OPhOMe is a click chemistry reagent containing azido and p-methoxyphenyl ester groups, which can be used for biomolecule conjugation and organic synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2546513-31-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151819. | |
| N-(3-Aminopropyl)cyclohexylamine | N-(3-Aminopropyl)cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermine synthase. N-(3-Aminopropyl)cyclohexylamine can be used for the research of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3312-60-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-W015514. | |
| (±)-N-3-Benzylnirvanol | (±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol are potent and selective cytochrome P450 inhibitors with Ki values of 0.25 and 5.3 μM for CYP2C19, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 93879-40-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-137258. | |
| N3-C3-NHS ester | N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 943858-70-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-126521. | |
| N3-C5-NHS ester | N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 866363-70-4. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-126523. | |
| N3-Cho bromide | N3-Cho (Azido-choline) bromide is a click chemistry reagent containing an azide group that can be used in the synthesis of cell membrane structures[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Azido-choline bromide. CAS No. 2059973-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W588725A. | |
| N3-Gly-Gly-Gly-Gly-Gly-OH | N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250433-77-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151777. | |
| N3-Gly-Gly-Gly-OH | N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved[1][2][3]. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1993176-75-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-151746. | |
| N3-Methyl-2-O-methyluridine | N3-Methyl-2-O-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7103-27-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-152358. | |
| N-3-oxo-dodecanoyl-L-homoserine lactone | N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex[1][2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OdDHL. CAS No. 168982-69-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114544A. | |
| N-(3-Oxooctanoyl)-DL-homoserine lactone | N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots [1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Rac)-3-oxo-C8-HSL. CAS No. 106983-27-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113801. | |
| N3-PEG2-C2-NHS ester | N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1312309-64-0. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-126526. | |
| N3-PEG3-C2-NHS ester | N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1245718-89-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-126528. | |
| N3-PEG3-CH2CH2COOH | N3-PEG3-CH2CH2COOH a PEG-based PROTAC linker can be used in the synthesis of BI-3663 (HY-111546), BI-4216 and BI-0319. Azido-PEG3-acid is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1056024-94-2. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-42490. | |
| N3-PEG3-vc-PAB-MMAE | N3-PEG3-vc-PAB-MMAE is a synthesized agent-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker. N3-PEG3-vc-PAB-MMAE shows potent antitumor activity. N3-PEG3-vc-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3046395-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100874. | |
| N3-PEG4-C2-NH2 | N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N3-PEG4-C2-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PROTAC Linker 20. CAS No. 951671-92-4. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-128834. | |
| N3-PEG4-C2-NHS ester | N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 944251-24-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-130109. | |
| N3-PEG5-C6-Cl | N3-PEG5-C6-Cl is a PEG PROTAC linker, can be used for synthesis of HALo PROTAC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1261238-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129621. | |
| N3-Ph-NHS ester | N3-Ph-NHS ester (compound 133) is an organic synthesis intermediate and ADC linker used for the synthesis of antibody-drug conjugate (ADC) molecules[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53053-08-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126524. | |
| N3PT | N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an Kd value of 22 nM (Apo-TK, transketolase lacking bound thiamine)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N3-pyridyl thiamine. CAS No. 13860-66-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16339. | |
| N3-TEMPO | N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 63697-61-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-151847. | |
| N-(4-((3-Methoxy-4-(1-(methyl-d3)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide | N-(4-((3-Methoxy-4-(1-(methyl-d3)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide is the deuterium labeled N-(4-((3-Methoxy-4-(1-(methyl)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide. Uses: Scientific research. Category: Signaling pathways. CAS No. 3074821-67-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-181527S. | |
| N4-Acetylcytidine triphosphate sodium | N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitrotranscription and it can be incorporated into multiple templates[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ac4CTP sodium. CAS No. 2803886-33-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111815A. | |
| N6022 | N6022 is a potent, selective, reversible, and efficacious S-Nitrosoglutathione reductase(GSNOR) inhibitor with IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1208315-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14984. | |
| N6-[(2-Azidoethoxy)carbonyl]-L-lysine | N6-[(2-Azidoethoxy) carbonyl]-L-lysine (UAA crosslinker 1) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy) carbonyl]-L-lysine mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy) carbonyl]-L-lysine is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UAA crosslinker 1. CAS No. 1167421-25-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-111434. | |
| N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride | N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UAA crosslinker 1 hydrochloride. CAS No. 1994331-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-111434A. | |
| N6,2-O-Dimethyladenosine | N6,2-O-Dimethyladenosine is a FTO substrate and reversible RNA modification. N6,2-O-Dimethyladenosine acts as a demethylation substrate for FTO, which removes its methyl groups. N6,2-O-Dimethyladenosine correlates with enhanced mRNA stability, improved translation efficiency and increased protein expression levels. N6,2-O-Dimethyladenosine is applicable to research related to obesity and colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57817-83-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101082. | |
| N6-Benzyladenosine | N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma[1]-[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Benzyladenosine. CAS No. 4294-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N7844. | |
| N6-Carbobenzoxy-L-lysine N-carboxyanhydride | N6-Carbobenzoxy-L-lysine N-carboxyanhydride is a lysine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1676-86-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W092115. | |
| N6-Cyclohexyladenosine | N6-Cyclohexyladenosine is a selective adenosine A1 receptor agonist (EC50 = 8.2 nM). N6-Cyclohexyladenosine enhances the activation of the PI3K/Akt/CREB/BDNF axis. N6-Cyclohexyladenosine promotes remyelination, induces sleep, and improves 3-NP-induced Huntington's disease. N6-Cyclohexyladenosine can be used in liver cancer research[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHA. CAS No. 36396-99-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18939. | |
| N6-Cyclopentyladenosine | N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. N6-cyclopentyladenosine increases Apoptosis. N6-Cyclopentyladenosine has antitumor activity against leukemia. N6-cyclopentyladenosine improves 5-fluorouracil (HY-90006)-induced hematopoietic damage, regulates sleep, and delays Aminophylline-induced clonic epileptic seizures[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CPA; UK-80882. CAS No. 41552-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103181. | |
| N6-Diazo-L-Fmoc-lysine | N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 159610-89-6. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W048205. | |
| N6-Ethyl-2-deoxyadenosine | N6-Ethyl-2-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 136050-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-154262. | |
| N6-Ethyladenosine | N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14357-08-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-111809. | |
| N6F11 | N6F11 is a selective ferroptosis inducer, and can selectively induce ferroptosis by targeting TRIM25-mediated GPX4 degradation in cancer cells while sparing immune cells. N6F11 initiates HMGB1-dependent antitumor immunity mediated by CD8+ T cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851398-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162065. | |
| N6-Isopentenyladenosine | N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Riboprine. CAS No. 7724-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-W011209. | |
| N-6-Methyl-2-deoxyadenosine | N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue. N-6-Methyl-2-deoxyadenosine targets nuclear processes and DNA replication machineries including WER, SATB1, TFAM, Jumu, SSBP1, DNA polymerase η and phage polymerase Gp90 exo-. N-6-Methyl-2-deoxyadenosine acts as a multifunctional epigenetic regulator that modulates transcription, DNA damage response, cell cycle, transposon silencing, stress adaptation, epigenetic crosstalk, and nucleosome organization in both prokaryotes and eukaryotes. N-6-Methyl-2-deoxyadenosine regulates mitochondrial epigenetic inheritance and is required for fear extinction memory in mice. N-6-Methyl-2-deoxyadenosine exhibits dysregulated levels in cancers. N-6-Methyl-2-deoxyadenosine can be used for the research of glioblastoma, triple negative breast cancer, and conditioned fear (fear extinction impairment)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m6dA. CAS No. 2002-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W011725. | |
| N-6-Methyl-2-deoxyadenosine-d3 | N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354782-02-7. Pack Sizes: 1 mg. Product ID: HY-W714356. | |
| N6-Methyladenosine | N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methyladenosine; N-Methyladenosine. CAS No. 1867-73-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0086. | |
| N6-Methyladenosine-13C | N6-Methyladenosine-13C is the 13C labeled isotope of N6-Methyladenosine[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methyladenosine-13C; N-Methyladenosine-13C. CAS No. 2232870-66-3. Pack Sizes: 1 mg. Product ID: HY-N0086S1. | |
| N6-Methyladenosine 5'-monophosphate disodium salt | N6-Methyladenosine 5'-monophosphate disodium salt is an N6-methyladenosine derivative and also the phosphorylated form of N6-methyladenosine. N6-Methyladenosine 5'-monophosphate disodium salt serves as an elution reagent for m6A-modified RNA in MeRIP assays[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81921-35-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-111926. | |
| N6-Methyladenosine-d3 | N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methyladenosine-d3; N-Methyladenosine-d3. CAS No. 139896-43-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0086S. | |
| N6-Methyladenosine (Standard) | N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion[1]. N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methyladenosine (Standard); N-Methyladenosine (Standard). CAS No. 1867-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 1 | |
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