MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Propylthiouracil | Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU. CAS No. 51-52-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0346. |  |
| Propyphenazone | Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Isopropylantipyrine; Isopropylphenazone. CAS No. 479-92-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-A0273. | |
| Propyzamide | Propyzamide is a anti-microtubule herbicide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Kerb; RH 315. CAS No. 23950-58-5. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-B1883. | |
| Proscillaridin A | Proscillaridin A is a potent poison of topoisomerase I/II activity with IC 50 values of 30 nM and 100 nM, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 466-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2331. | |
| Prostaglandin B2 | Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13367-85-6. Pack Sizes: 1 mg (29.90 mM * 100 μL in Methyl acetate); 5 mg (29.90 mM * 500 μL in Methyl acetate). Product ID: HY-113042. | |
| Prostaglandin D2 | Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals [1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances [2]. PGD2 plays a protective role by suppressing inflammation [3]. Uses: Scientific research. Group: Natural products. Alternative Names: PGD2. CAS No. 41598-07-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101988. | |
| Prostaglandin E1 | Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K i s of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3 , EP4 , EP2 , IP and EP1 , respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Alprostadil; PGE1. CAS No. 745-65-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0131. | |
| Prostaglandin E2 | Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Group: Natural products. Alternative Names: PGE2; Dinoprostone. CAS No. 363-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952. | |
| Prostaglandin F1a | Prostaglandin F1a is a compound that has the effect of contracting smooth muscle and lowering blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 745-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113459. | |
| Prostaglandin H2 | Prostaglandin H2 (PGH2), a potent vasoconstrictor, is produced by the conversion of Arachidonic acid (AA). Prostaglandin H2 is asubstrate for the production of Prostaglandins (PGs) and thromboxanes (TXs) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGH2. CAS No. 42935-17-1. Pack Sizes: 10 μg (283.71 μM * 100 μL in Acetone); 50 μg (283.71 μM * 500 μL in Acetone); 100 μg (283.71 μM * 1 mL in Acetone). Product ID: HY-136500. | |
| Prostaglandin J2 | Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with K i s of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC 50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PGJ2. CAS No. 60203-57-8. Pack Sizes: 500 μg (14.95 mM * 100 μL in Methyl acetate). Product ID: HY-113366. | |
| Prostratin | Prostratin, a natural terpenoid compound, is a PKC activator, with a K i of 12.5 nM and shows inhibitory effect on HIV-1. Uses: Scientific research. Group: Natural products. CAS No. 60857-08-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107421. | |
| PROTAC AR Degrader-8 | PROTAC AR Degrader-8 (Compound NP18) is the PROTAC degrader for androgen receptor ( AR ), that degrades AR-FL with DC 50 of 0.018 μM and 0.14 μM in 22Rv1 cell and LNCaP cell, degrades AR-V7 with DC 50 of 0.026 μM in 22Rv1 cell. PROTAC AR Degrader-8 inhibits the proliferation of cancer cell 22Rv1 and LNCaP with IC 50 of 0.038 μM and 1.11 μM. PROTAC AR Degrader-8 arrests cell cycle at G2/M phase, induces apoptosis in 22Rv1 cell. PROTAC AR Degrader-8 exhibits anticancer efficacy in mouse and zebrafish model [1]. (Pink: ligand for target protein AR ligand-33 (HY-170330); Black: linker (HY-W007731); Blue: ligand for E3 ligase Cereblon (HY-14658)). Uses: Scientific research. Group: Signaling pathways. CAS No. 3044108-04-2. Pack Sizes: 1 mg. Product ID: HY-170329. | |
| PROTAC ERα Degrader-1 | PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha ( ERα ) degrader. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417369-94-7. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112098. | |
| Protamine sulfate | Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9009-65-8. Pack Sizes: 100 mg. Product ID: HY-107911. | |
| Protease-Activated Receptor-1, PAR-1 Agonist | Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 141136-85-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2518. | |
| Protease-Activated Receptor-4 | Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4). Uses: Scientific research. Group: Peptides. CAS No. 245443-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0297. | |
| Protectin D1 | Protectin D1, a neuroprotectin D1 produced by neuronal cells, is a member of a newly discovered family of bioactive products derived from docosahexaenoic acid. Protectin D1 also serves as a specialized pro-resolving mediator, exhibiting effective in vivo pro-resolving activity in various human disease models. Additionally, Protectin D1 is an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways. Protectin D1 exerts anti-inflammatory effects by reducing ROS levels, inhibiting the expression of NALP3 , ASC , and Caspase-1 , and consequently decreasing the release of pro-inflammatory cytokines IL-1β and IL-18. Furthermore, Protectin D1 enhances miRNA-210 expression, activates the PI3K/AKT signaling pathway, and exerts cardioprotective effects. Protectin D1 holds promise for research in cardiovascular diseases and inflammatory disorders [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Neuroprotectin D1; NPD1. CAS No. 660430-03-5. Pack Sizes: 10 μg (138.7 μM * 200 μL in ethanol). Product ID: HY-130413. | |
| Protegrin-1 | Protegrin-1 is a antimicrobial peptide with antimicrobial activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PG1. CAS No. 168831-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1633. | |
| Protein A | Protein A (SPA) is an immunoglobulin (Ig) binding protein that exists on the surface of bacteria and can be freely secreted into the extracellular environment. Protein A blocks opsonization and phagocytosis and induces B-cell death in vitro by binding to the Fc region of antibodies and the Fab region of B-cell receptors. Protein A has the ability to inhibit opsonization and phagocytosis in vitro [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: SPA. CAS No. 308083-69-4. Pack Sizes: 5 mg. Product ID: HY-NP006. | |
| Proteinase, Aspergillus oryzae | Proteinase, Aspergillus oryzae refers to the enzymes with proteolytic activity. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9001-92-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-B2228. | |
| Proteinase K | Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K can be use for promoting methods of viral nucleic acid extraction, and detection [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Protease K. CAS No. 39450-01-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-108717. | |
| Protein kinase inhibitor 1 hydrochloride | Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM for HIPK2. Uses: Scientific research. Group: Signaling pathways. CAS No. 2321337-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00439A. | |
| Protein kinase inhibitor 6 | Protein kinase inhibitor 6 is a protein kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 348-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-47026. | |
| Prothioconazole | Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAU-6476. CAS No. 178928-70-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116568. | |
| Prothionamide | Protionamide (prothionamide) acts on tuberculosis and leprosy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Protionamide. CAS No. 14222-60-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0306. | |
| PROT-IN-1 | PROT-IN-1 (Compound 2) is a proline transporter ( PROT ) inhibitor ( IC 50 : 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329935-45-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153763. | |
| Protirelin | Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone; TRH. CAS No. 24305-27-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0002. | |
| Protirelin acetate | Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone acetate; TRH acetate. CAS No. 120876-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0002A. | |
| PROTO-1 | PROTO-1 is a hair cell protector and can be used in studies of ototoxicity-induced hair cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312951-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18673. | |
| Protoapigenone | Protoapigenone is an antineoplastic agent isolated from ferns. Protoapigenone has significant inhibitory activity against Hep G2, Hep 3B, MCF-7, A549 and MDAMB-231, with IC 50 s values of 1.60, 0.23, 0.78, 3.88 and 0.27 μg/mL respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 862884-32-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134008. | |
| Protocatechualdehyde | Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae , is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV. CAS No. 139-85-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0295. | |
| Protocatechuate 3,4-dioxygenase | Protocatechuate 3,4-dioxygenase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9029-47-4. Pack Sizes: 25 U. Product ID: HY-P2915. | |
| Protocatechuic acid | Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-Dihydroxybenzoic acid. CAS No. 99-50-3. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-N0294. | |
| Protocatechuic acid (Standard) | Protocatechuic acid (Standard) is the analytical standard of Protocatechuic acid. This product is intended for research and analytical applications. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Uses: Scientific research. Group: Natural products. CAS No. 99-50-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0294R. | |
| Protodioscin | Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties. Uses: Scientific research. Group: Natural products. CAS No. 55056-80-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0799. | |
| Protopine | Protopine (Corydinine), an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Corydinine. CAS No. 130-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0793. | |
| Protoporphyrin IX | Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 553-12-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-B1247. | |
| (+)-proto-Quercitol | (+)-proto-Quercitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Quercitol. CAS No. 488-73-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W145689. | |
| Protriptyline hydrochloride | Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Uses: Scientific research. Group: Signaling pathways. CAS No. 1225-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0949. | |
| Pro-xylane (30% in water) | Pro-xylane (30% in water) (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane (30% in water) has potential skin anti-aging properties and is eco-friendly, biodegradable, and can be used in cosmetic research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hydroxypropyl tetrahydropyrantriol. CAS No. 439685-79-7. Pack Sizes: 50 mg (1.56 M * 166.67 μL in Water); 100 mg (1.56 M * 333.33 μL in Water). Product ID: HY-108036. | |
| Proxyphylline | Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator [1]. Uses: Scientific research. Group: Natural products. CAS No. 603-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1742. | |
| Prucalopride | Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179474-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14151. | |
| Prucalopride succinate | Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-108512. CAS No. 179474-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12694. | |
| Prulifloxacin | Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NM441. CAS No. 123447-62-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0024. | |
| Prunasin | Prunasin is a inhibitor of DNA Polymerase β [1]. Uses: Scientific research. Group: Natural products. CAS No. 99-18-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1548. | |
| Prunetin | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-59-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2597. | |
| Prunin | Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC 50 of 5.5 μM [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Naringenin 7-0-glucoside. CAS No. 529-55-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1549. | |
| Prussian blue insoluble | Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron(III) ferrocyanide; Milori blue. CAS No. 14038-43-8. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-106594A. | |
| Pruvanserin | Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 281014 free acid; LY 2422347. CAS No. 443144-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106246. | |
| Pruvonertinib | YK-029A is an orally active inhibitor of mutant EGFR , targeting to both the T790M mutations (EGFR T790M ) and exon 20 insertion of EGFR (EGFRex20ins). YK-029A exhibits significant antitumor activity, and results tumor regression in EGFRex20ins-driven PDX models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YK-029A. CAS No. 2064269-82-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-155537. | |
| PRX-07034 hydrochloride | PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a K i = 4-8 nM and an IC 50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 903580-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14559. | |
| PRX-08066 | PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3. Uses: Scientific research. Group: Signaling pathways. CAS No. 866206-54-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15472. | |
| PS10 | PS10 is a novel, potent and ATP-competitive pan- PDK inhibitor, inhibits all PDK isoforms with IC 50 of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively. PS10 shows high affinity for PDK2 ( K d = 239 nM) than for Hsp90 (K d = 47 μM) [1]. PS10 improves glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity. PS10 has the potential for the investigation of diabetic cardiomyopathy [2].PDK: pyruvate dehydrogenase kinase. Uses: Scientific research. Group: Signaling pathways. CAS No. 1564265-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121744. | |
| PS210 | PS210 is a potent and selective PDK1 activator with a K d of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221962-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121629. | |
| PS423 | PS423 is a prodrug of PS210, acting as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K. PS210 is a potent and selective PDK1 activator targeting the PIF binding pocket of PDK1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221964-37-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124060. | |
| PS47 | PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13851. | |
| PS48 | PS48 is an activator of PDK1 with an AC 50 of 8 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15967. | |
| Psalmotoxin 1 | Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). Psalmotoxin 1 is a potent and slective ASIC1a inhibitor (IC 50 : 0.9 nM) by increasing the apparent affinity for H + of ASIC1a. Psalmotoxin 1 can induce cell apoptosis , also inhibits cell migration, proferliration and invasion of cancer cells. Psalmotoxin 1 can be used in the research of cancers, or neurological disease [1] [3] [4] [6]. Uses: Scientific research. Group: Peptides. Alternative Names: PcTx1; Psalmopoeus cambridgei toxin-1. CAS No. 880107-52-8. Pack Sizes: 100 μg. Product ID: HY-P1411. | |
| PSB-603 | PSB-603 is a potent and highly selective A 2B adenosine receptor antagonist exhibiting a K i value of 0.553 nM and virtually no affinity for the human and rat A 1 and A 2A and the human A 3 receptors up to a concentration of 10 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092351-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103166. | |
| PSB-CB5 | PSB-CB5 is a potent and selective antagonist of GRP18. PSB-CB5 has the potential for the research of metabolic disease and obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627710-30-8. Pack Sizes: 1 mg. Product ID: HY-44154. | |
| Pseudoginsenoside F11 | Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. Uses: Scientific research. Group: Natural products. Alternative Names: Ginsenoside A1. CAS No. 69884-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0541. | |
| Pseudoginsenoside RT5 | Pseudoginsenoside RT5 is isolated from Panax quinquefolium [1]. Uses: Scientific research. Group: Natural products. CAS No. 98474-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0542. | |
| Pseudohypericin | Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 55954-61-5. Pack Sizes: 1 mg. Product ID: HY-N0685. | |
| Pseudomonas quinolone signal | Pseudomonas Quinolone Signal (Compound C), a signaling molecule produced by Pseudomonas aeruginosa, can activate lasB. Pseudomonas Quinolone Signal can be used in the study of virulence regulation in Pseudomonas aeruginosa [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PQS. CAS No. 108985-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128200. | |
| Pseudomonic acid C | Pseudomonic acid C, an antibiotic, possesses antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71980-98-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133056. | |
| Pseudopelletierine | Pseudopelletierine is an alkaloid compound that can be used as a enzyme substrate [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 552-70-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W017353. | |
| Pseudoprotodioscin | Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides [1]. Uses: Scientific research. Group: Natural products. CAS No. 102115-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg; 50 mg. Product ID: HY-N0686. | |
| Pseudouridine | Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 1445-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113061. | |
| PSI | PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposis sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Proteasome Inhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO. CAS No. 158442-41-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1258. | |
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