MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MI-538 | MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1857417-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19810. |  |
| Mianserin | Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mianserine. CAS No. 24219-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0188. | |
| Mianserin hydrochloride | Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist. Mianserin hydrochloride can activate κ-opioid receptor and octopamine receptor. Mianserin hydrochloride increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin hydrochloride modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin hydrochloride can be used for the research of neurological disease, such as depression and epilepsy[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Org GB 94. CAS No. 21535-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0188A. | |
| Mibampator | Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY451395. CAS No. 375345-95-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10934. | |
| Mibavademab | Mibavademab is a CHO-expressed humanized antibody that targets LEPR/CD295. Mibavademab is equipped with a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.58 kDa. The isotype control for Mibavademab can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Signaling pathways. CAS No. 2305770-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990631. | |
| Mibefradil dihydrochloride | Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 40-5967 dihydrochloride. CAS No. 116666-63-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-15553A. | |
| Mibenratide | Mibenratide, a small cyclic peptide, is an adrenergic β1 receptor antagonist. Mibenratide can be used for heart failure research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1239011-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3557. | |
| Micafungin | Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FK463. CAS No. 235114-32-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17579. | |
| Micafungin sodium | Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FK 463 sodium. CAS No. 208538-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16321. | |
| Miclxin | Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS37262926. CAS No. 2494198-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138301. | |
| Miconazole | Miconazole (R18134) is an imidazole antifungal agent that can pass through the blood-brain barrier. Miconazole also has antibacterial effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R18134. CAS No. 22916-47-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-B0454. | |
| Microbial Transglutaminase | Microbial Transglutaminase (MTG) is a transglutaminase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTG; MTGase; Protein-glutamine-γ-glutamyltransferase. CAS No. 80146-85-6. Pack Sizes: 30 U. Product ID: HY-E70452. | |
| Microcolin B | Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule[1]. Uses: Scientific research. Category: Natural products. CAS No. 141205-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130999. | |
| Microcolin H | Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408008-21-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-163001. | |
| microRNA-21-IN-2 | microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303018-40-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151516. | |
| microRNA-21-IN-3 | microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766106-83-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153534. | |
| Microsomal aminopeptidase, Microorganism | Microsomal aminopeptidase, Microorganism is first reported from C. elegans. The Microsomal aminopeptidase, Microorganism is beneficial for the development of molecular vaccines against parasitic nematodes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9054-63-1. Pack Sizes: 25 U; 50 U; 100 U. Product ID: HY-P2779. | |
| Micvotabart | HY-P990927 is an FN1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: PYX-201 Antibody. CAS No. 2867549-73-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990927. | |
| MID-1 | MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 312608-54-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115461. | |
| Midecamycin | Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SF-837; Antibiotic SF-837. CAS No. 35457-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-B1908. | |
| Midodrine | Midodrine is a selective and orally active adrenergic α1-receptor agonist. Midodrine can strengthen vascular contraction. Midodrine can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Midodrin. CAS No. 42794-76-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12749. | |
| Midodrine hydrochloride | Midodrine hydrochloride ((±)-Midodrine hydrochloride) is a selective and orally active adrenergic α1-receptor agonist. Midodrine hydrochloride can strengthen vascular contraction. Midodrine hydrochloride can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Midodrine hydrochloride. CAS No. 43218-56-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-12749A. | |
| Midostaurin | Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PKC412; CGP 41251. CAS No. 120685-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10230. | |
| Midostaurin (Standard) | Midostaurin (Standard) is the analytical standard of Midostaurin. This product is intended for research and analytical applications. Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PKC412 (Standard); CGP 41251 (Standard). CAS No. 120685-11-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10230R. | |
| MIF098 | MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1208448-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147390. | |
| Mifamurtide | Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTP-PE; L-MTP-PE; CGP 19835. CAS No. 83461-56-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13682. | |
| Mifamurtide sodium | Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium. CAS No. 90825-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13682B. | |
| Mifepristone | Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RU486; RU 38486. CAS No. 84371-65-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-13683. | |
| Mifepristone-d6 | Mifepristone-d6 is deuterated labeled Mifepristone (HY-13683). Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RU486-d6; RU 38486-d6. CAS No. 1228097-18-4. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-13683S2. | |
| Mifepristone (Standard) | Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RU486 (Standard); RU 38486 (Standard). CAS No. 84371-65-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-13683R. | |
| Migalastat hydrochloride | Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GR181413A. CAS No. 75172-81-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14929A. | |
| Miglitol | Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY1099; BAY-m1099. CAS No. 72432-03-2. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-B0481. | |
| Miglustat | Miglustat (N-Butyldeoxynojirimycin) is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat can be used for the research of type I gaucher disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Butyldeoxynojirimycin; NB-DNJ; OGT 918. CAS No. 72599-27-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17020. | |
| Miglustat hydrochloride | Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor, with blood-brain barrier permeability. Miglustat hydrochloride can be used for the research of type I gaucher disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Butyldeoxynojirimycin hydrochloride; NB-DNJ hydrochloride; OGT 918 hydrochloride. CAS No. 210110-90-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17020A. | |
| Migoprotafib | Migoprotafib (GDC-1971) (compound 199) is a SHP2 inhibitor. Migoprotafib inhibits the MAPK/ERK signaling pathway, and exhibits antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-1971. CAS No. 2377352-49-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144903. | |
| MIK665 | MIK665 (S-64315), derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor[1]. MIK665 has an IC50 of 1.81 nM for MCL1[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-64315. CAS No. 1799631-75-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112218. | |
| Milademetan | Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-3032. CAS No. 1398568-47-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101266. | |
| Milademetan tosylate hydrate | Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-3032b; DS-3032 tosylate hydrate. CAS No. 2095625-97-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101266B. | |
| Milatuzumab | Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hLL1; MEDI-115. CAS No. 899796-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99731. | |
| Milbemycin A3 | Milbemycin A3 is a 16-membered macrocyclic lactone compound found in the soil bacterium Saccharopolyspora hygroscopicus subsp. aureolacrimosus. Milbemycin A3 enhances the opening of glutamate- and GABA-gated chloride channels and exhibits insecticidal activity. Milbemycin A3 can be used in insect resistance-related research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51596-10-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130423. | |
| Milbemycin A4 | Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1]sup>[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51596-11-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126906. | |
| Milbemycin oxime | Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129496-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0778. | |
| Milbemycin oxime (Standard) | Milbemycin oxime (Standard) is the analytical standard of Milbemycin oxime. This product is intended for research and analytical applications. Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129496-10-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0778R. | |
| Milciclib | Milciclib (PHA-848125) is a potent, ATP-competitive and dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC50s of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, cyclin B/CDK1 and TRKA, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHA-848125. CAS No. 802539-81-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10424. | |
| Militarine | Militarine is a plant growth inhibitor and anti-inflammatory agent. Militarine inhibits the elongation of radicles and hypocotyls in seedlings of lettuce, Italian ryegrass and timothy grass. Militarine alleviates PM2.5-induced inflammatory injury and inhibits cell migration in human alveolar epithelial A549 cells by inhibiting the NF-κB signaling pathway, reducing oxidative stress and the release of inflammatory factors. Militarine can be used in studies related to PM2.5-induced pulmonary diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58139-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-122308. | |
| Millepachine | Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1393922-01-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7591. | |
| Milrinone | Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Win 47203. CAS No. 78415-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-14252. | |
| Milrinone lactate | Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Win 47203 lactate. CAS No. 100286-97-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14252A. | |
| Miltefosine | Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity[1][2][3][4]. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT)[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HePC; Hexadecyl phosphocholine. CAS No. 58066-85-6. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-13685. | |
| Miltirone | Miltirone is an orally active natural compound found in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC50 of 0.3 μM. Miltirone induces ROS - and-p53 dependent apoptosis. Miltirone inhibits carboxylesterase 2 (CES2; Ki = 0.04 μM) and SARS-CoV main protease (Mpro)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rosmariquinone. CAS No. 27210-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N1951. | |
| Milvexian | Milvexian is an orally bioavailable, small-molecule, reversible, direct antagonists of factor Xia, with the Ki of 0.11, 0.38, 0.64, 490, 350 nM for human, rabbit, dog, rat, mouse, respectively. Milvexian shows anti-thrombosis activity in vitro and in vivo, and can be used for thrombus study[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986177; JNJ-70033093. CAS No. 1802425-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125856. | |
| Mimosine | Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity[1]. Mimosine is a known chelator of Fe(III)[2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells[3]. Anti-cancer, antiinflammation. Uses: Scientific research. Category: Signaling pathways. CAS No. 500-44-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N0928. | |
| Mindeudesivir | GS-621763-d1 is the deuterium labeled GS-621763 (HY-145119)[1]. GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VV116 free base; GS-621763-d1. CAS No. 2647442-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-145119S. | |
| Mindeudesivir hydrobromide | Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir (HY-104077), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VV116; GS-621763-d1 hydrobromide. CAS No. 2779498-79-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145119AS. | |
| Minnelide | Minnelide is a prodrug of triptolide that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide promotes apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1254702-87-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124584. | |
| Minocycline | Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10118-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17412A. | |
| Minocycline hydrochloride | Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13614-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 2 g; 5 g; 10 g. Product ID: HY-17412. | |
| Minoxidil | Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: U10858. CAS No. 38304-91-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0112. | |
| Minoxidil sulfate | Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83701-22-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B1445. | |
| Minretumomab | Minretumomab (CC-49) is a murine monoclonal antibody against TAG-72 (tumor-associated glycoprotein 72). Minretumomab is used in cancer and immunity research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-49. CAS No. 195189-17-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99732. | |
| Minzasolmin | Minzasolmin (UCB0599; (R)-NPT200-11) is an orally active, blood-brain-permeable α-synuclein (α-Syn) inhibitor that selectively binds to α-Syn misfolded intermediates (such as oligomers) and inhibits aggregation and fibril formation by regulating their conformational stability. Minzasolmin can reduce the generation of pathological oligomers and block neurotoxic signaling, thereby reducing the abnormal accumulation of α-Syn in the brain. Minzasolmin significantly improved motor deficits, reduced neuroinflammatory markers, and α-Syn-related pathological deposition in transgenic mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB0599; (R)-NPT200-11. CAS No. 1802518-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145580. | |
| Mipomersen | Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen can be used for the research of homozygous familial hypercholesterolemia (HoFH)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 301012 free base. CAS No. 1000120-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148647. | |
| Mipomersen sodium | Mipomersen sodium (ISIS 301012) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen sodium can be used for the research of homozygous familial hypercholesterolemia (HoFH)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 301012. CAS No. 629167-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108764. | |
| MIPS521 | MIPS521 is a positive allosteric modulator of adenosine A1 receptor (A1AR). MIPS521 also has a lower A1R allosteric affinity (pKB=4.95; KB=11?μM). MIPS521 exhibits pain-relieving effects in vivo through modulation of the increased levels of endogenous adenosine[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1146188-19-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139644. | |
| Miquelianin | Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. Miquelianin is also a CBR1 inhibitor. Miquelianin is permeable to the blood-brain barrier[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Quercetin 3-O-glucuronide; Quercetin 3-glucuronide. CAS No. 22688-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13930. | |
| MIR002 | MIR002 is a potent and orally active DNA polymerase α (POLA1) and HDAC 11 dual inhibitor. MIR002 induces acetylation of p53, activation of p21, G1/S cell cycle arrest, and apoptosis. MIR002 shows significant antitumor activity in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2217671-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143412. | |
| miR-21-IN-2 | miR-21-IN-2 is a high-affinity miR-21 inhibitor. miR-21-IN-2 binds to the apical loop region of the pre-miR-21 hairpin, inhibits Dicer-mediated processing, and thereby blocks the biosynthesis of mature miR-21. miR-21-IN-2 can be used for the research of microRNA-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 304880-74-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-130487. | |
| Mirabegron | Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YM178. CAS No. 223673-61-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14773. | |
| Miransertib | Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research[1]. Miransertib is effective against Leishmania[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARQ-092. CAS No. 1313881-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719. | |
| Miransertib hydrochloride | Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research[1]. Miransertib hydrochloride is effective against Leishmania[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARQ-092 hydrochloride. CAS No. 1313883-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719A. | |
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