MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MeOSuc-Ala-Phe-Lys-AMC TFA | MeOSuc-Ala-Phe-Lys-AMC TFA is a peptide substrate of plasmin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201853-92-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P4347. |  |
| MeO-Suc-Arg-Pro-Tyr-pNA | MeOSuc-Arg-Pro-Tyr-pNA (S-2586) is a biological active peptide. (chymotrypsin substrate). Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-2586. CAS No. 82564-18-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5376. | |
| Mepazine | Mepazine (Pecazine) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pecazine. CAS No. 60-89-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-121282. | |
| Mepazine hydrochloride | Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine hydrochloride affects viability of ABC-DLBCL cells by enhancing apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pecazine hydrochloride. CAS No. 2975-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-121282A. | |
| Mepenzolate bromide | Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. Mepenzolate bromide can be used to suppress the gastrointestinal hypermotility associated with irritable bowel syndrome[1].Mepenzolate bromide is a GPR109A inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76-90-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-17585. | |
| Mephenytoin | Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1184. | |
| Mepolizumab | Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 240563. CAS No. 196078-29-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9945. | |
| Mepolizumab (anti-IL5) | Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 196078-29-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9945A. | |
| Meptyldinocap | Meptyldinocap (2,4-DNOPC) is a fungicide and cytotoxic agent that acts against powdery mildew. Meptyldinocap upregulates the phosphorylation levels of ERK1/2, JNK and p38. Meptyldinocap induces apoptosis and endoplasmic reticulum stress, disrupts calcium homeostasis, inhibits cell proliferation and migration, downregulates the expression of proliferation- and pregnancy-related genes, and triggers mitochondrial dysfunction. Meptyldinocap can be used in studies related to powdery mildew and implantation failure[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DNOPC. CAS No. 131-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17522. | |
| Mepyramine maleate | Mepyramine maleate, a first generation antihistamine, is an antagonist of histamine H1 receptor, with Kds of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pKd of 9.4 for H1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrilamine maleate. CAS No. 59-33-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B1281. | |
| Mequitazine | Mequitazine is a potent, and long-acting histamine H1 antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LM-209. CAS No. 29216-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2168. | |
| Merafloxacin | Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI-934. CAS No. 91188-00-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139010. | |
| Merbarone | Merbarone (NSC 336628) is an orally active inhibitor of topoisomerase II. Merbarone acts primarily by blocking topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes. Merbarone is an anticancer agent[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 336628. CAS No. 97534-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19024. | |
| Merbromin | Merbromin is a mixed inhibitor of the 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2, with an IC50 of 2.7 μM. Merbromin effectively inhibits the replication of the Zika virus (ZIKV) and shows anti-ZIKV activity by inhibiting ZIKVpro. Merbromin can also be used as a topical disinfectant for cuts and scrapes, and it serves as a biological dye[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mercury dibromofluorescein disodium salt; ZP1. CAS No. 129-16-8. Pack Sizes: 500 mg; 1 g. Product ID: HY-B0961. | |
| Merestinib | Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY2801653. CAS No. 1206799-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15514. | |
| Mergetpa | Mergetpa is a reversible Arg-carboxypeptidase inhibitor with high affinity. Mergetpa reduces B1R. Mergetpa blocks the overexpression of IL-1β protein and mRNA in glucose-fed rats. Mergetpa significantly increases the expression of IL-1β protein in the renal cortex. Mergetpa is used to block the conversion of kinins and B2 receptor antagonists into metabolites lacking the C-terminal arginine. Mergetpa inhibits the time-dependent enhancement of the response of isolated rabbit aorta to bradykinin. Mergetpa preserves the chemotactic activity of full-length SDF-1α on cells. Mergetpa reverses hyperglycemia, excessive weight gain, elevated levels of oxidative stress markers and overexpression of inflammatory markers in glucose-fed rats[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77102-28-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W704574. | |
| Merimepodib | Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-497; MMPD. CAS No. 198821-22-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13986. | |
| Meropenem | Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM 7338. CAS No. 96036-03-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-13678. | |
| Meropenem-d6 | Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM 7338-d6. CAS No. 1217976-95-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13678S. | |
| Meropenem trihydrate | Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM 7338 trihydrate. CAS No. 119478-56-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13678A. | |
| Meropenem trihydrate (Standard) | Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM 7338 trihydrate (Standard). CAS No. 119478-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13678AR. | |
| Meropenem-vaborbactam | Meropenem-vaborbactam (Carbavance) is a Carbapenem Antibiotic and Boronic acid-based beta-lactamase inhibitor, is a fixed-dose combination product with potent in vitro activity against Enterobacteriaceae that are Klebsiella pneumoniae carbapenemase producers. Meropenem-vaborbactam exhibits activity against Pseudomonas aeruginosa isolates , with an MIC50 of 0.5 μg/mL and an MIC90 of 8 μg/mL[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbavance. CAS No. 2031124-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111521. | |
| Mertansine | Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM1; Maytansinoid DM1. CAS No. 139504-50-0. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-19792. | |
| MES | MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Morpholinoethanesulphonic acid. CAS No. 4432-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-D0858. | |
| Mesaconic acid | Mesaconic acid is an active product that can be extracted from Saxifraga stolonifera. Mesaconic acid is used as a fire retardant and is a competitive inhibitor of fumarate reduction[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Citronic acid; Methylfumaric acid. CAS No. 498-24-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-78036. | |
| Mesaconitine | Mesaconitine is a nitric oxide synthase activator. Mesaconitine drives extracellular Na+ and Ca2+ influx into endothelial cells, increases intracellular Na+ and Ca2+ concentrations, and triggers nitric oxide release. Mesaconitine is applicable for pain-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2752-64-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0724. | |
| MES-d13 | MES-d13 is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352534-94-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0858S. | |
| Mesendogen | Mesendogen is a TRPM6 inhibitor. Mesendogen enhances the mesoderm and definitive endoderm (DE) differentiations of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). Mesendogen can be used for the research of magnesium homeostasis during early embryonic cell development[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864716-85-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103073. | |
| MES hydrate | MES (2-Morpholinoethanesulphonic acid) hydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES hydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Morpholinoethanesulphonic acid hydrate. CAS No. 1266615-59-1. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-D0858C. | |
| MES monohydrate | MES (2-Morpholinoethanesulphonic acid) monohydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES monohydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Morpholinoethanesulphonic acid monohydrate. CAS No. 145224-94-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 g. Product ID: HY-D0858A. | |
| meso-Erythritol | meso-Erythritol is a sugar alcohol that found in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and can be used as low-calorie sweetener food additives[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149-32-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-100551. | |
| meso-Erythritol-d6 | meso-Erythritol-d6 is the deuterium labeled meso-Erythritol (HY-100551). meso-Erythritol is a sugar alcohol that found in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and can be used as low-calorie sweetener food additives[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2714435-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146567S. | |
| meso-Tetra(4-pyridyl)porphine | meso-Tetra(4-pyridyl)porphine (Compound 10) is a porphyrin derivative. meso-Tetra(4-pyridyl)porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC50 value greater than 50 μM. meso-Tetra(4-pyridyl)porphine can be used in tumor research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16834-13-2. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W008874. | |
| Mesotrione | Mesotrione is a herbicide belongs to the benzoylcyclohexanedione family. Mesotrione is a potent and competitive and reversible inhibitor of HPPD enzyme. Mesotrione is selective to maize due to rapid metabolism and relative high tolerance by the susceptible crop plant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104206-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-12853. | |
| MES potassium | MES (2-Morpholinoethanesulphonic acid) potassium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES potassium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Morpholinoethanesulphonic acid potassium. CAS No. 39946-25-3. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-D0858E. | |
| MES sodium salt | MES sodium salt (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES sodium salt is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Morpholinoethanesulphonic acid sodium salt. CAS No. 71119-23-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 50 g. Product ID: HY-D0858B. | |
| Metaflumizone | Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAS-320I. CAS No. 139968-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-116448. | |
| Metalaxyl | Metalaxyl is a fungicide agent that inhibits the protein synthesis in fungi. Metalaxyl against downy mildews and soil-borne diseases by Phytium ssp. and Phytophthora ssp.[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57837-19-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0843. | |
| Metalaxyl-M | Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Metalaxyl. CAS No. 70630-17-0. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0843A. | |
| Metalaxyl-M-d6 | Metalaxyl-M-d6 ((R)-Metalaxyl-d6) is the deuterium labeled Metalaxyl-M (HY-B0843A). Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1398112-32-7. Pack Sizes: 1 mg (35.04 mM * 100 μL in Acetonitrile). Product ID: HY-B0843AS. | |
| Metalaxyl-M (Standard) | Metalaxyl-M ((R)-Metalaxyl) (Standard) is the analytical standard of Metalaxyl-M (HY-B0843A). This product is intended for research and analytical applications. Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Metalaxyl (Standard). CAS No. 70630-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0843AR. | |
| Metallo β-lactamase ligand 1 | Metallo-beta-lactamase ligand 1 is a class B β-lactamase inhibitor with antibacterial activity extracted from patent WO2019221122A1, compound A[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1087784-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-136306. | |
| Metamizole sodium | Metamizole sodium (Dipyrone) is an orally active cyclooxygenase (COX) inhibitor. Metamizole sodium can inhibit cell proliferation and promote cell apoptosis. Metamizole sodium has anti-inflammatory and antioxidant activities. Metamizole sodium is an antipyretic, analgesic and spasmolytic agent. Metamizole sodium can be used in research to relieve a variety of pain[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dipyrone; Methamizole sodium. CAS No. 68-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B1279A. | |
| Metanephrine | Metanephrine is the O-methylated metabolite of epinephrine that can be used for the research of diagnosis of pheochromocytoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5001-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-113299. | |
| Metaphosphoric acid, 33.5-36.5% | Metaphosphoric acid, 33.5-36.5% (Glacial phosphoric acid, 33.5-36.5%) is a precipitant used for rapid enzymatic measurement of blood lactate and pyruvate. Metaphosphoric acid, 33.5-36.5% can also be used as a dehydrating agent, and its derivative sodium hexametaphosphate can be used as a chelating agent and food additive[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glacial phosphoric acid, 33.5-36.5%. CAS No. 37267-86-0. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y1939A. | |
| Metaproterenol hemisulfate | Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Metaproterenol sulfate. CAS No. 5874-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-B1276. | |
| Metaraminol tartrate | Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist[1]. Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Metaradrine tartrate. CAS No. 33402-03-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-B1116. | |
| Metarrestin | Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML246. CAS No. 1443414-10-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120118. | |
| Meta-topolin | Meta-Topolin (m-Topolin) is a highly active aromatic cytokinin. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m-Topolin. CAS No. 75737-38-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-112104. | |
| MeTC7 | MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1817841-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147337. | |
| Metcamifen | Metcamifen is a herbicide safener that can protect rice from Clodinafop-propargyl (HY-136380)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129531-12-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W775385. | |
| Metformin | Metformin (1,1-Dimethylbiguanide) inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide. CAS No. 657-24-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0627. | |
| Metformin-d6 hydrochloride | Metformin-d6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide-d6 hydrochloride. CAS No. 1185166-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-110228. | |
| Metformin hydrochloride | Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide hydrochloride. CAS No. 1115-70-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-17471A. | |
| Metformin hydrochloride (Standard) | Metformin hydrochloride (Standard) is the analytical standard of Metformin hydrochloride (HY-17471A). This product is intended for research and analytical applications. Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide hydrochloride (Standard). CAS No. 1115-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17471AR. | |
| Met-Gly-Pro-AMC | Met-Gly-Pro-AMC is a fluorescent peptide substrate of MetAP2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1926163-52-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4344. | |
| Methacholine chloride | Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetyl-β-methylcholine chloride. CAS No. 62-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-A0083. | |
| Methacrylic acid N-hydroxysuccinimide ester | Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NHS-MA. CAS No. 38862-25-8. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W105423. | |
| Methacycline hydrochloride | Methacycline hydrochloride is a tetracycline antibiotic and can inhibits bacterial protein synthesis. Methacycline hydrochloride is a potent epithelial-mesenchymal transition (EMT) inhibitor. Methacycline hydrochloride blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline hydrochloride is an antimicrobial and has the potential for pulmonary fibrosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3963-95-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-B0449. | |
| Methapyrilene | Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 91-80-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111130. | |
| Methazolamide | Methazolamide (L584601) is a BBB-penetrable and orally active carbonic anhydrase inhibitor, with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide can reduce intraocular pressure and has a neuroprotective effect, being able to inhibit neuronal apoptosis. Methazolamide can be used in the research of ophthalmic diseases such as glaucoma and cerebrovascular diseases such as subarachnoid hemorrhage[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L584601. CAS No. 554-57-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0553. | |
| Methdilazine hydrochloride | Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1229-35-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B1690A. | |
| Methicillin sodium salt | Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Meticillin sodium. CAS No. 132-92-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0974. | |
| Methimazole | Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thiamazole. CAS No. 60-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0208. | |
| Methionine | Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MRX-1024; D-Methionine. CAS No. 348-67-4. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g. Product ID: HY-13694. | |
| Methionine sulfoximine | Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase with convulsive effects. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine, which may provide important insights in neurobiological research. Methionine sulfoximine has also been used to study mechanisms related to epilepsy and its inhibitory potential[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Amino-4-(S-methylsulfonimidoyl)butanoic acid. CAS No. 1982-67-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W338140. | |
| Methiothepin mesylate | Methiothepin (Metitepine) mesylate is a potent and non-selective 5-HT2 receptor antagonist, with pKds of 7.10 (5-HT1A), 7.28 (5HT1B), 7.56 (5HT1C), 6.99 (5HT1D), 7.0 (5-HT5A), 7.8 (5-HT5B), 8.74 (5-HT6), and 8.99 (5-HT7), and pKis of 8.50 (5HT2A), 8.68 (5HT2B), and 8.35 (5HT2C). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Metitepine mesylate; Ro 8-6837 mesylate. CAS No. 74611-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-107836. | |
| Methisazone | Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Marboran. CAS No. 1910-68-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124564. | |
| Methocarbamol | Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 532-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-B0262. | |
| Methoctramine tetrahydrochloride | Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. Methoctramine tetrahydrochloride can inhibit Muscarine (HY-121404)-induced bradycardia in vivo. Methoctramine tetrahydrochloride can be used in the study of cardiovascular diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104807-46-7. Pack Sizes: 5 mg. Product ID: HY-116294A. | |
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