MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Mecbotamab | Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BA301. CAS No. 2460400-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9988. |  |
| Mecbotamab vedotin | Mecbotamab vedotin (BA3011) is a pH dependent antibody drug conjugate (ADC) targeting AXL. Mecbotamab vedotin can significantly inhibit AXL in DU145 cells and LCLC-103H cells and kills cells. Mecbotamab vedotin can be used for research on cancer such as lung cancer, pancreatic cancer and prostate cancer. The antibody component is Mecbotamab (HY-P9988), and the ADC toxin molecule is Monomethyl auristatin E (MMAE) (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BA3011; CAB-Axl-ADC; CAB-anti-Axl-ADC. CAS No. 2460400-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-145622. | |
| Mecillinam | Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amdinocillin; FL 1060. CAS No. 32887-01-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0269. | |
| Meclizine dihydrochloride | Meclizine (Meclozine) dihydrochloride, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Meclozine dihydrochloride. CAS No. 1104-22-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 5 g. Product ID: HY-B0349. | |
| Meclocycline | Meclocycline is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgarisis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2013-58-3. Pack Sizes: 1 mg. Product ID: HY-B1366A. | |
| Meclofenamic acid | Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Meclofenamate. CAS No. 644-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117275. | |
| Meclofenamic acid sodium | Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Meclofenamate sodium. CAS No. 6385-02-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-B1320. | |
| Meclonazepam | Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect[1]. Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 11-3128; Ro 11-3128/002. CAS No. 58662-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-101725. | |
| Medetomidine-13C,d3 hydrochloride | Medetomidine-13C,d3 (hydrochloride) is a deuterated labeled Medetomidine (hydrochloride)[1]. Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPV785-13C,d3. CAS No. 1216630-06-6. Pack Sizes: 1 mg. Product ID: HY-17034BS1. | |
| Medetomidine hydrochloride | Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPV785. CAS No. 86347-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17034B. | |
| MEDI-3617 | MEDI-3617 is a humanized antibody expressed in CHO cells, targeting Ang2/ANGPT2/Angiopoietin2. MEDI-3617 has a huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for MEDI-3617 can refer to Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 1415642-51-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990625. | |
| MEDI-570 | MEDI-570 is a humanized antibody expressed in CHO that targets ICOS/CD278. MEDI-570 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for MEDI-570 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2179209-59-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990628. | |
| Medicagenic acid | Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes[1]. Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Castanogenin. CAS No. 599-07-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2472. | |
| Medronic acid | Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methylenediphosphonic acid. CAS No. 1984-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-108309. | |
| Medroxyprogesterone acetate | Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Medroxyprogesterone 17-acetate; Farlutin. CAS No. 71-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0469. | |
| Mefenamic acid | Mefenamic acid is a BBB-permeable and non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 61-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0574. | |
| Mefentrifluconazole | Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1417782-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136063. | |
| Mefloquine | Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mefloquin. CAS No. 53230-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-17437. | |
| Mefloquine hydrochloride | Mefloquine hydrochloride (Mefloquin hydrochloride), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine hydrochloride is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine hydrochloride can be used for malaria, systemic lupus erythematosus and cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mefloquin hydrochloride. CAS No. 51773-92-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-17437A. | |
| Mefluleucine | Mefluleucine (NV-5138), a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. Mefluleucine is used for antidepressant studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NV-5138. CAS No. 2095886-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114384. | |
| Mefluleucine hydrochloride | Mefluleucine (NV-513) hydrochloride, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. Mefluleucine hydrochloride is used for antidepressant studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NV-5138 hydrochloride. CAS No. 2639392-70-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-114384B. | |
| Mefox | Mefox is a degradation product of folic acid (HY-16637)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79573-48-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121652. | |
| Megestrol acetate | Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 595-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-13676. | |
| mEH-IN-1 | mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2418576-06-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146696. | |
| Me-IQ | Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl-IQ. CAS No. 77094-11-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141638. | |
| MeIQx | MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2. CAS No. 77500-04-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W355129. | |
| MEISi-1 | MEISi-1 is a homeodomain inhibitor of small molecule MEIS1 protein. MEISi-1 significantly inhibited the activity of luciferase reporter genes containing MEIS binding sites (TGACAG) and induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 446306-43-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134258. | |
| MEISi-2 | MEISi-2 is a selective inhibitor of MEIS, a key regulator of hematopoietic stem cell (HSC) self-renewal. MEISi-2 is developed for the research of cardiac injuries, hematopoiesis issues, bone marrow transplantations, and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250156-71-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134259. | |
| Meisoindigo | Meisoindigo (Dian III), a derivative of Indirubin (HY-N0117), halts the cell cycle at the G0/G1 phase and induces apoptosis in primary acute myeloid leukemia (AML) cells. Meisoindigo exhibits high antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dian III; N-Methylisoindigotin; Natura-α. CAS No. 97207-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13680. | |
| Melagatran | Melagatran is a reversible, selective, orally active direct inhibitor of thrombin with a Ki of 2 nM. Melagatran binds directly to the active site of thrombin, inhibiting thrombin-mediated conversion of fibrinogen to fibrin. Melagatran reduces the DNA binding activity of NF-κB and AP-1. Melagatran reduces fibrin deposition in organs, alleviates ischemic brain damage, and reduces the size of advanced atherosclerotic lesions. Melagatran can be used in the study of cardiovascular disease (coronary thrombosis, atherosclerosis) and ischemic brain damage[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 159776-70-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129056. | |
| Melamine-15N3 | Melamine-15N3 is a 15N-labeled Melamine. Melamine is a metabolite?of?cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287476-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-Y1117S. | |
| Melanin | Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. Uses: Scientific research. Category: Signaling pathways. CAS No. 8049-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113485. | |
| Melanin Concentrating Hormone, salmon | Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCH (salmon). CAS No. 87218-84-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1525. | |
| Melanotan I | Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MT-I; [Nle4,D-Phe7]-α-MSH. CAS No. 75921-69-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2466. | |
| Melanotan (MT)-II | Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning. Uses: Scientific research. Category: Signaling pathways. CAS No. 121062-08-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0267. | |
| Melarsoprol | Melarsoprol, a melaminophenylarsine-type trivalent organic arsenical, is an important agent for African trypanosomiasis. Melarsoprol inhibits the growth of lymphoid leukemic cell by inducing apoptosis. Melarsoprol crosses the blood-brain barrier[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 494-79-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119594. | |
| Melatonin | Melatonin is a hormone made by the pineal gland that can activate melatonin receptor and inhibit PANoptosis. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetyl-5-methoxytryptamine. CAS No. 73-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-B0075. | |
| Melatonin-d3 | Melatonin-d3 is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetyl-5-methoxytryptamine-d3. CAS No. 90735-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-B0075S1. | |
| Melatonin-d4 | Melatonin-d4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetyl-5-methoxytryptamine-d4. CAS No. 66521-38-8. Pack Sizes: 1 mg. Product ID: HY-B0075S. | |
| Meldonium | Meldonium (MET-88) functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2). Meldonium exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium is a fatty acid oxidation inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MET-88; Quaterin. CAS No. 76144-81-5. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-B1836. | |
| Meldonium dihydrate | Meldonium (MET-88) dihydrate functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2). Mildronate dihydrate exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium dihydrate is a fatty acid oxidation inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MET-88 dihydrate; Quaterin dihydrate. CAS No. 86426-17-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1836A. | |
| Melevodopa hydrochloride | Melevodopa hydrochloride is an effervescent Levodopa (HY-N0304) prodrug. Levodopa is an orally active metabolic precursor of neurotransmitters dopamine and has anti-allodynic effects and the potential for Parkinson's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421-65-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W011963. | |
| Melflufen hydrochloride | Melflufen (Melphalan flufenamide) hydrochloride, a dipeptide proagent of Melphalan, is an alkylating agent. Melflufen hydrochloride shows antitumor activity against multiple myeloma (MM) cells and inhibits angiogenesis. Melflufen hydrochloride induces irreversible DNA damage and cytotoxicity in MM cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Melphalan flufenamide hydrochloride. CAS No. 380449-54-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105019A. | |
| Melissic acid | Melissic acid, which belongs to the category of long-chain saturated fatty acids. It is a 30-carbon straight-chain fatty acid found in a variety of natural sources, including beeswax and coconut oil. Due to its unique physical properties, such as high melting point and viscosity, Melissic acid has a variety of uses in industry. It can be used as a lubricant in the production of some plastics and rubber, and is also used in the manufacture of surfactants and detergents. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Triacontanoic acid. CAS No. 506-50-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N8451. | |
| Melitidin | Melitidin is a flavanone glycoside, that can be isolated from Citrus grandis 'Tomentosa'. Melitidin shows a good antitussive effect on cough induced by citric acid in Guinea pig[1]. Uses: Scientific research. Category: Natural products. CAS No. 1162664-58-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10620. | |
| Melittin | Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20449-79-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0233. | |
| MELK-8a hydrochloride | MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NVS-MELK8a hydrochloride. CAS No. 2096992-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100368A. | |
| Meloxicam | Meloxicam is a non-steroidal antiinflammatory agent that can pass through the blood-brain barrier, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 71125-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0261. | |
| Meloxicam (Standard) | Meloxicam (Standard) is the analytical standard of Meloxicam. This product is intended for research and analytical applications. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 71125-38-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0261R. | |
| Melperone | Melperone is a butyrophenone with atypical antipsychotic properties. Melperone is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values ??of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone is also a CYP2D6 inhibitor. Melperone can be used for the study of schizophrenia, and agitation in the elderly[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3575-80-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2169. | |
| Melredableukin alfa | Melredableukin alfa (RG7835) is a bivalent conjugate composed of a human IL-2 mutant (T3A, N88D, C125A) and human IgG1. Melredableukin alfa exhibits enhanced Treg cell selectivity in cynomolgus monkey and humanized mouse models. Melredableukin alfa can be used in research related to ulcerative colitis and autoimmune hepatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG7835; RO7049665. CAS No. 2056881-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99728. | |
| Melrilimab | Melrilimab (GSK 3772847) is an IgG2-kappa anti-IL1RL1/ST2/IL33R/DER4/FIT-1 monoclonal antibody. Melrilimab can be used for the research of asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK 3772847; CNTO-7160. CAS No. 2222865-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99729. | |
| Memantine | Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist. Memantine can be used for the research of moderate-to-severe Alzheimer's disease (AD)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19982-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0591. | |
| Menadiol | Menadiol (Dihydrovitamin K3), a menaquinol analogue, is an electron donor for reversed oxidative phosphorylation in submitochondrial particles[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dihydrovitamin K3. CAS No. 481-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W128525. | |
| Menadione | Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin K3. CAS No. 58-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0332. | |
| Menadione bisulfite sodium | Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Menadione sodium bisulfite; Vitamin K3 sodium bisulfite. CAS No. 130-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B1897A. | |
| Menaquinone-4 | Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin K2(MK-4); Menaquinone K4. CAS No. 863-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-B2156. | |
| Menaquinone 6 | Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84-81-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138137. | |
| Menaquinone-7 | Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin K2-7; Vitamin K2(35); Vitamin MK-7. CAS No. 2124-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112499. | |
| Menaquinone-7 (Standard) | Menaquinone-7 (Standard) is the analytical standard of Menaquinone-7. This product is intended for research and analytical applications. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin K2-7(Standard); Vitamin K2(35)(Standard); Vitamin MK-7 (Standard). CAS No. 2124-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112499R. | |
| Menaquinone 9 (Standard) | Menaquinone 9 (Standard) is the analytical standard of Menaquinone 9. This product is intended for research and analytical applications. Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 523-39-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131501R. | |
| Menin-MLL inhibitor MI-2 | Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1271738-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15222. | |
| (-)-Menthol | (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i[1]. Antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2216-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-75161. | |
| (+)-Menthol | (+)-Menthol (D-Menthol) is one of the optical isomers of Menthol. (+)-Menthol can reduce the electrically evoked contractions of rat phrenic hemidiaphragm in vitro. Local anaesthetic activity. (+)-Menthol inhibits fungal growth and sporulation. (+)-Menthol can also inhibit the growth of Microcystis aeruginosa cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Menthol. CAS No. 15356-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W017277. | |
| (-)-Menthol (Standard) | (-)-Menthol (Standard) is the analytical standard of (-)-Menthol. This product is intended for research and analytical applications. (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i[1]. Antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2216-51-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-75161R. | |
| Menthone | Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10458-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-N2381. | |
| (-)-Menthyl acetate | (-)-Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol and also a skin penetration enhancer for 5-aminolevulinic acid (ALA). (-)-Menthyl acetate exhibits strong ALA skin penetration-enhancing activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Menthyl acetate. CAS No. 2623-23-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-N7132. | |
| MeOSuc-AAPF-CMK | MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH Cl) is a potent proteinase K inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MeOSuc-Ala-Ala-Pro-Phe-CH2Cl. CAS No. 137259-05-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5994. | |
| MeOSuc-AAPV-AMC | MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72252-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136865. | |
| MeOSuc-AAPV-CMK | MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Elastase Inhibitor III. CAS No. 65144-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136888. | |
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