MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MAC glucuronide phenol-linked SN-38 | MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2246380-69-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128943. |  |
| Macimorelin acetate | Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EP-1572 acetate; AEZS-130 acetate. CAS No. 945212-59-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-14820A. | |
| Macitentan | Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACT-064992. CAS No. 441798-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14184. | |
| Macitentan-d4 | Macitentan-d4 is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACT-064992-d4. CAS No. 1258428-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14184S. | |
| Macozinone | Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PBTZ169. CAS No. 1377239-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12903. | |
| Macranthoidin B | Macranthoidin B (Macranthoiside I) is an orally active triterpene saponin. Macranthoidin B inhibits epithelial-mesenchymal transition in endometriosis via the COX - 2/PGE2 pathway, and also induces tumor cell apoptosis and inhibits their proliferation by regulating metabolism and increasing ROS levels. Macranthoidin B can be used in studies related to endometriosis, colorectal cancer and hepatocellular carcinoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Macranthoiside I. CAS No. 136849-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0864. | |
| Maculosin | Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties[1][2][3][4][5][6][7][8][9].Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cyclo(Tyr-Pro). CAS No. 4549-2-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1940. | |
| Macupatide | Macupatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Macupatide improves insulin secretion responses and insulin sensitivity.Macupatide can be used for the research of type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3532226. CAS No. 2923558-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10959. | |
| Macurin | Macurin is a xanthone that can be isolated from Garcinia lancilimba[1]. Uses: Scientific research. Category: Natural products. Alternative Names: Maclurin. CAS No. 519-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N3347. | |
| Madecassic acid | Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18449-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0569. | |
| Madecassic acid (Standard) | Madecassic acid (Standard) is the analytical standard of Madecassic acid. This product is intended for research and analytical applications. Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18449-41-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0569R. | |
| Madecassoside | Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB[5][6], exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Asiaticoside A. CAS No. 34540-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0568. | |
| Madecassoside (Standard) | Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB[5][6], exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Asiaticoside A (Standard). CAS No. 34540-22-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0568R. | |
| Madrasin | Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DDD00107587. CAS No. 374913-63-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100236. | |
| MAFP | MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor of cPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor of anandamide amidase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl Arachidonyl Fluorophosphonate. CAS No. 188404-10-6. Pack Sizes: 1 mg (26.99 mM * 100 μL in Methyl acetate); 5 mg (26.99 mM * 500 μL in Methyl acetate); 10 mg (26.99 mM * 1 mL in Methyl acetate); 25 mg (26.99 mM * 2.5 mL in Methyl acetate); 50 mg (26.99 mM * 5 mL in Methyl acetate); 100 mg (26.99 mM * 10 mL in Methyl acetate). Product ID: HY-103334. | |
| Magainin 1 | Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Magainin I. CAS No. 108433-99-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0269. | |
| Magainin 2 | Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa[1]. Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Magainin II. CAS No. 108433-95-0. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0270. | |
| Mag-Fluo-4 AM | Mag-Fluo-4 AM is a fluorecent Ca2+ chelator, with high affinity for calcium. Mag-Fluo-4 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1097709-31-3. Pack Sizes: 50 μg. Product ID: HY-D1498. | |
| MAGL-IN-1 | MAGL-IN-1 is a potent, selective, reversible and competitive inhibitor of MAGL, with an IC50 of 80 nM. MAGL-IN-1 exhibits anti-proliferative effects against human breast, colorectal, and ovarian cancer cells. MAGL-IN-1 blocks MAGL in cell-based as well as in vivo assays[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2324160-91-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111538. | |
| MAGL-IN-3 | CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50=34.1 nM). It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain. Uses: Scientific research. Category: Signaling pathways. CAS No. 2514-37-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-139182. | |
| MAGL-IN-4 | MAGL-IN-4 is an orally active, selective and reversible monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 6.2 nM. MAGL-IN-4 can penetrate the blood-brain barrier (BBB). MAGL-IN-4 enhances endocannabinoid signaling mostly by the increase in the level of 2-AG via selective MAGL inhibition in the brain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2135785-20-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132310. | |
| Magnesium chloride hexahydrate, for molecular biology | Magnesium chloride hexahydrate (MgCl2 hexahydrate), for molecular biology is the hexahydrate form of magnesium dichloride. Magnesium chloride hexahydrate can be used as a source of magnesium ion and a co-foactor for many enzymes. Magnesium chloride hexahydrate increases the activity of Ca2+ ATPase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MgCl2 hexahydrate, for molecular biology. CAS No. 7791-18-6. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-W019981B. | |
| Magnesium glycinate | Magnesium glycinate (Magnesium bisglycinate), the magnesium salt of glycine, is a nutrient supplement. Magnesium glycinate has satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Magnesium is an essential mineral that plays a critical role in the human body. Magnesium takes part in the process of energy metabolism and assists the maintenance of normal muscle function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Magnesium bisglycinate; Magnesium diglycinate. CAS No. 14783-68-7. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-129328. | |
| Magnesium ionophore I | Magnesium ionophore I (ETH 1117) serves as the primary component for the development of calcium-magnesium selective electrodes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ETH 1117. CAS No. 75513-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W674112. | |
| Magnesium sulfate | Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7487-88-9. Pack Sizes: 50 g. Product ID: HY-Y1267. | |
| Magnolioside | Magnolioside, isolated from Angelica gigas Nakai (Umbelliferae), exhibits significant neuroprotective activities against glutamate-induced toxicity[1]. Uses: Scientific research. Category: Natural products. CAS No. 20186-29-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7034. | |
| Magnolol | Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 μM and 17.7 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 528-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0163. | |
| Magrolimab | Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab, an IgG4 isotype, lacks ADCC function and exhibits relatively weak ADCP effector function. Magrolimab can be used for the study of malignant bone tumors and breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hu5F9-G4. CAS No. 2169232-81-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99029. | |
| Mahanine | Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research. Uses: Scientific research. Category: Signaling pathways. CAS No. 28360-49-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121368. | |
| MAK683 | MAK683 is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1951408-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103663. | |
| Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan | Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan (LP1) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB (HY-173635) to make antibody agent conjugate (ADC), AZD0516 (HY-173639)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3059991-66-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173634. | |
| Malabaricone A | Malabaricone Ais a natural product isolated fromM. malabarica[1]. Uses: Scientific research. Category: Natural products. CAS No. 63335-23-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N9973. | |
| Malabaricone B | Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63335-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N8517. | |
| Malabaricone C | Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63335-25-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N8518. | |
| Malachite green-d5 (picrate) | Malachite green-d5 (picrate) is the deuterium labeled Malachite green picrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1258668-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-143824S. | |
| Mal-amide-PEG4-Val-Cit-PAB-OH | Mal-amide-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker containing a Maleimide group. Mal-amide-PEG4-Val-Cit-PAB-OH is used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1949793-41-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126672. | |
| Mal-amide-PEG8-Val-Ala-PAB-PNP | Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2210247-59-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148425. | |
| Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (Mal-PEG2-AZD) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mal-PEG2-AZD. CAS No. 1037589-69-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113697. | |
| Mal-amido-PEG4-acid | Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263045-16-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-130414. | |
| Mal-amido-PEG4-NHS ester | Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756525-99-2. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-W040134. | |
| Mal-amido-PEG6-NHS ester | Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1137109-21-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W008879. | |
| Mal-amido-PEG8-NHS ester | Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756525-93-6. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-W040133. | |
| Malaoxon | Malaoxon is a pesticide metabolite. Malaoxon can induce cellular death in cultured human pulmonary cells. Malaoxon can be used for the research of pulmonary toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1634-78-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-119904. | |
| MALAT1-IN-1 | MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 827327-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115579. | |
| Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT | DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2396667-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164367. | |
| Mal-C2-Gly3-EDA-PNU-159682 | Mal-C2-Gly3-EDA-PNU-159682, a agent-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126688. | |
| Mal-(CH2)5-Val-Cit-PAB-Eribulin | Mal-(CH2)5-Val-Cit-PAB-Eribulin is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-microtubule agent, Eribulin, linked via linker Mal-(CH2)5-Val-Cit-PAB[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2130869-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139642. | |
| Mal-Deferoxamine | Mal-Deferoxamine is a maleimide-functionalized trihydroxamate siderophore derivative that can be isolated from Streptomyces pilosus. Mal-Deferoxamine possesses highly specific Fe (III) chelating ability, and the stability of complexes formed between it and non-Fe (III) metal ions is significantly lower. Mal-Deferoxamine exhibits growth inhibitory effects against Gram-positive bacteria, but shows no obvious inhibitory activity against Gram-negative bacteria (MIC>50 μM). Mal-Deferoxamine is mainly suitable for scientific research in hematology and related fields[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1638156-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-132989. | |
| MAL-di-EG-Val-Cit-PAB-MMAE | MAL-di-EG-Val-Cit-PAB-MMAE consists the ADCs linker (MAL-di-EG-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Uses: Scientific research. Category: Signaling pathways. CAS No. 2746391-62-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100567. | |
| Maleic acid | Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. Uses: Scientific research. Category: Signaling pathways. CAS No. 110-16-7. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 5 g. Product ID: HY-Y0367. | |
| Maleic acid-d2 | Maleic Acid-d2 is the deuterium labeled Maleic Acid[1]. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleic-2,3-d2 acid. CAS No. 24461-33-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0367S. | |
| Maleimide-DOTA | Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimido-mono-amide-DOTA. CAS No. 1006711-90-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133540. | |
| Mal-Exatecan | Mal-Exatecan is a Mal (Maleimide) modified Exatecan (HY-13631), a DNA topoisomerase I (topoisomerase I) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3028213-52-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-159783. | |
| Mal-GGFG-PAB-MMAE | Mal-GGFG-PAB-MMAE (Compound 8) is a drug-linker conjugate, which is composed of the mitotic inhibitor MMAE (HY-15162) and the linker Mal-GGFG-PAB. Mal-GGFG-PAB-MMAE can be used for synthesis of antibody-drug conjugate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055607-18-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-170512. | |
| Mal-Gly-PAB-Exatecan-D-glucuronic acid | Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763252-25-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153179. | |
| Malic acid | Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxybutanedioic acid; E 296. CAS No. 6915-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 50 g; 100 g. Product ID: HY-Y1311. | |
| Malic enzyme inhibitor ME1 | Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ME1. CAS No. 522649-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124861. | |
| Mal-L-PA-NH-Boc | Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: mDPR(boc); (S)-MALEOYL-DPR(BOC)-OH·DCHA. CAS No. 1491152-23-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-41919. | |
| Mal-NH-ethyl-SS-propionic acid | Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2128735-24-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140120. | |
| Malondialdehyde tetrabutylammonium | Malondialdehyde tetrabutylammonium is a quaternary ammonium salt formed by the decomposition of polyunsaturated fatty acids in plant cell membranes. Malondialdehyde tetrabutylammonium can be used for the quantification of malondialdehyde, a biomarker of lipid peroxidation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100683-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W749411. | |
| Malonyl CoA lithium | Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Malonyl coenzyme A lithium. CAS No. 108347-84-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136408. | |
| malonyl-NAC | malonyl-NAC increases cellular propylation, resulting in reduced endogenous GAPDH activity. malonyl-NAC increases GAPDH malonylation in cells and inhibits pyruvate kinase activity. In addition, malonyl-NAC limits the metabolism and proliferation of a highly glycolytic kidney cancer cell line harboring a tricarboxylic acid cycle mutation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361327-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157395. | |
| Mal-PEG12-NHS ester | Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2669737-09-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-140963. | |
| Mal-PEG24-NHS ester | Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226733-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135819. | |
| Mal-PEG2-acid | Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374666-32-6. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-130442. | |
| Mal-PEG2-alcohol | Mal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34321-81-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140968. | |
| Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 | Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 (Compound DC-2) is a drug-linker conjugate for ADC. Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 consists of a NMT inhibitor (HY-160945) and a stable and cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032302-82-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-171814. | |
| Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan | Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a bioactive drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC). Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is applicable to ADC synthesis and cancer research. Exatecan acts as a DNA Topoisomerase I inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599439-54-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-153795. | |
| Mal-PEG2-NHS | Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329364-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138430. | |
| Mal-PEG2-NHS ester | Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester. Uses: Scientific research. Category: Signaling pathways. CAS No. 1433997-01-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126504. | |
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