MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| LP-211 | LP-211 is a selective and blood brain barrier penetrant 5-HT7 receptor agonist, with a Ki of 0.58 nM, with high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 1052147-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111455. |  |
| LP44 hydrochloride | LP44 (hydrochloride) is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 824958-12-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103101. | |
| LP-471756 | LP-471756 is a potent GPR139 antagonist with an IC50 value of 640 nM. LP-471756 inhibits LP-360924-stimulated cAMP production[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 413605-11-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119168. | |
| LP-533401 | LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. Uses: Scientific research. Category: Signaling pathways. CAS No. 945976-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15849. | |
| LP-922761 | LP-922761 is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1454808-95-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120179. | |
| LP-935509 | LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 (AAK1) with an IC50 of 3.3 nM and a Ki of 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 shows antinociceptive activity. LP-935509 can be used for neuropathic pain and SARS-CoV-2 research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1454555-29-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117626. | |
| L-Palmitoylcarnitine | L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2364-67-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg. Product ID: HY-113147. | |
| L-Palmitoylcarnitine chloride | L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18877-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113147A. | |
| L-Palmitoylcarnitine-d3 hydrochloride | L-Palmitoylcarnitine-d3 hydrochloride is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334532-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-113147AS. | |
| LPAR1 antagonist 1 | LPAR1 antagonist 1 (compound 18) is a potent, oral active and selective LPAR1 antagonist with the IC50 of 3.3 nM. LPAR1 antagonist 1 can be used for study of fibrosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032275-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162267. | |
| L-p-Boronophenylalanine | L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-BPA. CAS No. 76410-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g. Product ID: HY-W087830. | |
| LPd peroxida probe-1 | LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1448846-35-2. Pack Sizes: 50 μg. Product ID: HY-D1412. | |
| L-Phenylalanine | L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid. CAS No. 63-91-2. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0215. | |
| L-Phenylalanine-13C6 | L-Phenylalanine-13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-13C6. CAS No. 180268-82-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0215S8. | |
| L-Phenylalanine-13C9 | L-Phenylalanine-13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-13C9. CAS No. 439685-11-7. Pack Sizes: 1 mg. Product ID: HY-N0215S10. | |
| L-Phenylalanine-15N | L-Phenylalanine-15N is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-15N. CAS No. 29700-34-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0215S5. | |
| L-Phenylalanine-3-13C | L-Phenylalanine-3-13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-3-13C. CAS No. 136056-02-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0215S7. | |
| L-Phenylalanine-d5 | L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-d5. CAS No. 56253-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0215S12. | |
| L-Phenylalanine-d8 | L-Phenylalanine-d8 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid-d8. CAS No. 17942-32-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0215S1. | |
| L-Phenylalanine (Standard) | L-Phenylalanine (Standard) is the analytical standard of L-Phenylalanine. This product is intended for research and analytical applications. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Amino-3-phenylpropionic acid (Standard). CAS No. 63-91-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0215R. | |
| L-Phenylmercapturic acid-d5 | L-Phenylmercapturic acid-d5 is the deuterium labeled L-Phenylmercapturic acid (HY-143368)[1]. L-Phenylmercapturic acid is often used as a biomarker for exposure to aniline compounds such as aniline and xylene[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1331906-27-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-143368S. | |
| L-Pipecolic acid | L-Pipecolic acid (H-HoPro-OH) is an oral active metabolite of Lysine and can accumulate in the bodily fluids of infants with autosomal inherited diseases, such as Zellweger syndrome and neonatal adrenal insufficiency. L-Pipecolic acid can promote muscle cell health and growth by enhancing protein synthesis, and plays a role in promoting gut health. L-Pipecolic acid holds promise for research in the fields of metabolic disorders, muscle growth disorders, and intestinal diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-HoPro-OH. CAS No. 3105-95-1. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W012734. | |
| Lp-PLA2-IN-1 | Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1420367-28-7. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19757. | |
| L-Proline | L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 147-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0252. | |
| L-Proline-13C5 | L-Proline-13C5 is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 201740-83-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0252S. | |
| L-Proline-13C5,15N | L-Proline-13C5,1-15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 202407-23-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-Y0252S4. | |
| L-Proline-d3 | L-Proline-d3 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 65807-22-9. Pack Sizes: 50 mg. Product ID: HY-Y0252S1. | |
| L-Proline-d7 | L-Proline-d7 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 39063-89-3. Pack Sizes: 10 mg. Product ID: HY-Y0252S5. | |
| L-Propargylglycine | (S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes[1]. (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Aminopent-4-ynoic acid. CAS No. 23235-01-0. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W006064. | |
| LpxH-IN-AZ1 | LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 901260-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130836. | |
| L-Pyroglutamic acid-d5 | L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. Uses: Scientific research. Category: Signaling pathways. CAS No. 1086136-22-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-76082S. | |
| LQFM215 | LQFM215 is a proline transporter (PROT) inhibitor. LQFM215 inhibits proline transport by competitively binding to the active site of PROT. LQFM215 effectively reduces hyperlocomotion and enhances social interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3044047-98-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161137. | |
| L-Quebrachitol | L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants. L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 642-38-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-N2375. | |
| LQZ-7F | LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC50s of 2.99 and 2.47 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 354543-09-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-122678. | |
| LR-17 | LR-17 (TLT-1 (94-110)), a 17-aa peptide, is a TREM-1 inhibitor. LR-17 shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS). LR-17 can be used for the study of sepsis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TLT-1 (94-110). CAS No. 1256099-50-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11077. | |
| LRE1 | LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase. Uses: Scientific research. Category: Signaling pathways. CAS No. 1252362-53-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100524. | |
| LRRK2-IN-1 | LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 of 6 nM and 13 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234480-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10875. | |
| LRRKtide | LRRKtide is a polypeptide substrate. LRRKtide is a specific phosphorylation substrate of LRRK2, a kinase associated with Parkinson's disease, and its phosphorylation site is a threonine residue. LRRKtide can be used for characterization of the catalytic properties of LRRK2, as well as studies on kinase activity and inhibition. LRRKtide is applicable to research related to Parkinson's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1071466-49-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5979. | |
| LS-102 | LS-102 is a selective E3 ubiquitin ligase synoviolin (Syvn1) inhibitor. LS-102 inhibits the autoubiquitination of synoviolin with an IC50 of 35 μM. LS-102 has the potential for rheumatoid arthritis treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1456891-34-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135844. | |
| LSD1/HDAC6-IN-2 | LSD1/HDAC6-IN-2 (JBI-802) is an orally active LSD1/HDAC6/MAO-A inhibitor, with IC50 values of 5 nM, 11 nM, and 5 nM, respectively. LSD1/HDAC6-IN-2 can inhibit the growth of multiple myeloma cells MM.1S, MM.1R, and RPMI-8226. LSD1/HDAC6-IN-2 can be used for research on diseases such as acute myeloid leukemia and lymphoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2982787-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164099. | |
| LSD1/TLK1-IN-1 | LSD1/TLK1-IN-1 is an orally active LSD1, TLK1, TLK2, TTK inhibitor with an LSD1 IC50 of 0.247 μM. LSD1/TLK1-IN-1 suppresses phosphorylation of Nek1 at T141 and Rad9 at S328, abrogates the TLK1>Nek1>ATR>Chk1 axis, protects H3K4me1/2 from demethylation, and does not affect LSD2, MAO-A, or MAO-B. LSD1/TLK1-IN-1 induces apoptosis, bypasses cell-cycle arrest, suppresses tumor growth, downregulates PD-L1 expression, enhances T-cell killing response, inhibits gastric cancer cell proliferation. LSD1/TLK1-IN-1 can be used for the research of prostate cancer and gastric cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: J54; J3-54. CAS No. 4734-59-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149213. | |
| L-Selenocystine | L-Selenocystine is a selenium-containing amino acid. L-Selenocystine has redox properties. L-Selenocystine is cytotoxic to various tumor cells and can induce the production of ROS and apoptosis. L-Selenocystine can block the Nrf2 and autophagy pathways. L-Selenocystine has anti-tumor activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29621-88-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-129960. | |
| L-SelenoMethionine | L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3211-76-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B1000A. | |
| L-SelenoMethionine (Standard) | L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3211-76-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1000AR. | |
| L-Sepiapterin | L-Sepiapterin (Sepiapterin), is a phenylalanine hydroxylase activator, is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression. L-Sepiapterin can be used for the study of hyperphenylalaninemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sepiapterin. CAS No. 17094-01-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-112234. | |
| L-Serine | L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Serine. CAS No. 56-45-1. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g. Product ID: HY-N0650. | |
| L-Serine-13C3 | L-Serine-13C3 is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Serine-13C3; (S)-Serine-13C3. CAS No. 201595-68-8. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0650S. | |
| L-Serine-13C3,15N,d3 | L-Serine-13C3,15N,d3 is the deuterium, 13C-, and 15-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Serine-13C3,15N,d3; (S)-Serine-13C3,15N,d3. CAS No. 1994299-33-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0650S3. | |
| L-Serine-15N | L-Serine-15N is the 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Serine-15N; (S)-Serine-15N. CAS No. 59935-32-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0650S10. | |
| LSKL, Inhibitor of Thrombospondin (TSP-1) | LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 283609-79-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0299. | |
| LSKL, Inhibitor of Thrombospondin (TSP-1) TFA | LSKL, Inhibitor of Thrombospondin (TSP-1) TFA is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) TFA can readily crosse the blood-brain barrier[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2828433-17-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0299A. | |
| LSN3160440 | LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein-protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2765539-59-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153193. | |
| LSN 3213128 | LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) with IC50 of 16 nM. LSN 3213128 exhibits anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1941211-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107981. | |
| LSN3318839 | LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R). LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2764704-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142162. | |
| LSN3353871 | LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds to Kringle IV (KIV) 8, KIV7-8 and KIV5-8, with Kd of 756 nM, 605 nM and 423 nM, respectively. LSN3353871 disrupts the formation of Lp(a) with the IC50 of 1.69 μM. LSN3353871 has oral bioactivity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2565657-20-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158424. | |
| LSTc | LSTc (LS-tetrasaccharide c) is a human lactooligosaccharide presents on glycoproteins and glycolipids. LSTc is also a specific human JC polyomavirus (JCV) recognition motif. LSTc has good potential for the study of progressive multifocal leukoencephalopathy (PML)[1]. Uses: Scientific research. Category: Natural products. Alternative Names: LS-tetrasaccharide c. CAS No. 64003-55-0. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N10633. | |
| LT052 | LT052 is a highly selective BET BD1 inhibitor with an IC50 of 87.7 nM. LT052 exhibits nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2 (IC50=12.130 μM). LT052 has anti-inflammatory?activity and can be used for acute gout arthritis research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2543545-44-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130622. | |
| LtaS-IN-1 | LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 877950-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135813. | |
| LTGO-33 | LTGO-33 is a potent and selective voltage-gated sodium channel NaV1.8 inhibitor. LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. LTGO-33 exhibits state-independent inhibition with similar potencies on channels in the closed and inactivated conformations. LTGO-33 inhibits native TTX-R NaV1.8 currents in non-human primate and human DRG neurons, where it reduces action potential firing. LTGO-33 can be used for pain disorders research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2834106-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157802. | |
| L-Theanine | L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood-brain barrier and is orally active[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine. CAS No. 3081-61-6. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 200 mg. Product ID: HY-15121. | |
| L-Theanine-d5 | L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutamic Acid γ-ethyl amide-d5; Nγ-Ethyl-L-glutamine-d5. CAS No. 1217451-85-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15121S. | |
| L-Thioproline | L-Thioproline is a proline derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34592-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g. Product ID: HY-W012676. | |
| L-Threonic acid magnesium | L-Threonic acid magnesium (Magnesium L-threonate) is the enantiomer of Threonic acid and the metabolite of vitamin C (HY-B0166). L-Threonic acid magnesium is a magnesium supplementation, that improves the brain magnesium concentration, inhibits the activation of TNF-α/NF-κB signaling pathway. L-Threonic acid magnesium can be used in research of Alzheimers disease. L-Threonic acid magnesium is orally active[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Magnesium L-threonate. CAS No. 778571-57-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134240. | |
| L-Threonine | L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72-19-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0658. | |
| L-Threonine-13C4 | L-Threonine-13C4 is the 13C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55443-53-3. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-N0658S6. | |
| L-Threonine-13C4,15N | L-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202468-39-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0658S3. | |
| L-Thyroxine | L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levothyroxine; T4. CAS No. 51-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-18341. | |
| L-Tryptophan | L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan; Tryptophane. CAS No. 73-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0623. | |
| L-Tryptophan-13C | L-Tryptophan-13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-13C; Tryptophane-13C. CAS No. 115709-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0623S1. | |
| L-Tryptophan-13C11 | L-Tryptophan-13C11 is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-13C11; Tryptophane-13C11. CAS No. 202114-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0623S2. | |
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