MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| L-Tryptophan-13C11,15N2 | L-Tryptophan-13C11,15N2 is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-13C11,15N2; Tryptophane-13C11,15N2. CAS No. 202406-50-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0623S4. |  |
| L-Tryptophan-15N | L-Tryptophan-15N is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-15N; Tryptophane-15N. CAS No. 99404-62-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0623S7. | |
| L-Tryptophan-15N2 | L-Tryptophan-15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-15N2; Tryptophane-15N2. CAS No. 204634-20-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0623S8. | |
| L-Tryptophan-d3 | L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-d3; Tryptophane-d3. CAS No. 133519-78-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0623S9. | |
| L-Tryptophan-d5 | L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-d5; Tryptophane-d5. CAS No. 62595-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0623S. | |
| L-Tryptophan-d8 | L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan-d8; Tryptophane-d8. CAS No. 1233395-93-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0623S5. | |
| L-Tryptophan (standard) | L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tryptophan (standard); Tryptophane (standard). CAS No. 73-22-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0623R. | |
| LTURM34 | LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM). LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1879887-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101667. | |
| LTV-1 | LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM. LTV-1 has the potential for autoimmunity treatment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 347379-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18667. | |
| L-Tyrosine | L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tyrosine. CAS No. 60-18-4. Pack Sizes: 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0473. | |
| L-Tyrosine-13C | L-Tyrosine-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. CAS No. 110622-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0473S4. | |
| L-Tyrosine-13C6 | L-Tyrosine-13C6 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. CAS No. 201595-63-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0473S2. | |
| L-Tyrosine-13C9 | L-Tyrosine-13C9 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. CAS No. 55443-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0473S3. | |
| L-Tyrosine-d2 | L-Tyrosine-d2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. CAS No. 72963-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0473S8. | |
| L-Tyrosine-d4 | L-Tyrosine-d4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 62595-14-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0473S. | |
| L-Tyrosine disodium salt | L-Tyrosine (disodium) is a tyrosine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69847-45-6. Pack Sizes: 10 mM * 1 mL in Water; 10 g; 25 g. Product ID: HY-N0473A. | |
| L-Tyrosine Hydrazide | L-Tyrosine Hydrazide is a tyrosine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7662-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 25 g. Product ID: HY-W142000. | |
| L-Tyrosine (Standard) | L-Tyrosine (Standard) is the analytical standard of L-Tyrosine. This product is intended for research and analytical applications. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tyrosine (Standard). CAS No. 60-18-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0473R. | |
| LU-002i | LU-002i is a subunit-selective human proteasome β2c and β2i inhibitor with an IC50 value of 220 nM for β2i[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1838705-22-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157034. | |
| Lubabegron | Lubabegron is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron demonstrates antagonistic behavior at the β1 and β?2 receptor subtypes and agonistic behavior at the β?3 receptor subtype in cattle. Lubabegron reduces NH3 gas emissions from an animal or its waste. Lubabegron is available as an animal supplement[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-488756. CAS No. 391920-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123012. | |
| Lubiprostone | Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RU-0211; SPI-0211. CAS No. 136790-76-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0679. | |
| Lucanthone | Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1). Uses: Scientific research. Category: Signaling pathways. CAS No. 479-50-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2098. | |
| Lucatumumab | Lucatumumab (HCD122) is a fully human anti-CD40 antagonist monoclonal antibody, which blocks CD40/CD40L-mediated signaling. Lucatumumab efficiently mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and clearance of tumor cells, can be used for refractory lymphomas, CLL and multiple myeloma research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HCD122. CAS No. 903512-50-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99167. | |
| Lucerastat | Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NB-DGJ; N-(n-Butyl)deoxygalactonojirimycin. CAS No. 141206-42-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106392. | |
| Luciferase (bacterial) | Luciferase (bacterial) catalyzes the oxidation of a long-chain aldehyde and reduced flavin mononucleotide. Luciferase (bacterial) protection against oxidative stress for bacterial luminescence[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9014-00-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1004. | |
| Luciferase, firefly | Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 61970-00-1. Pack Sizes: 1 mg. Product ID: HY-P1004A. | |
| Luciferase-IN-1 | Luciferase-IN-1 is a luciferase inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10205-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136706. | |
| Luciferase-IN-3 | Luciferase-IN-3 (compound 5h) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 3.2 μM, while the inhibitory potency against R. reniformis is not significant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 690987-97-4. Pack Sizes: 1 mg. Product ID: HY-158256. | |
| Lucifer Yellow CH dipotassium salt | Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71206-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W127715. | |
| Lucigenin | Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC-151912; L-6868. CAS No. 2315-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0720. | |
| Lucitanib | Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-3810. CAS No. 1058137-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15391. | |
| Luc Yellow CH dilithium | Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67769-47-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128692. | |
| LUF6000 | LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 890087-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13236. | |
| LUF7244 | LUF7244 is a selective allosteric modulator of Kv11.1 channels. LUF7244 inhibits early afterdepolarizations. LUF7244 can be used for anti-arrhythmia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1821638-43-0. Pack Sizes: 5 mg. Product ID: HY-137986. | |
| Lufenuron | Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103055-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-115584. | |
| Lufotrelvir | Lufotrelvir (PF-07304814), a phosphate proagent of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-07304814. CAS No. 2468015-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-138078. | |
| Luisol A | Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 225110-59-8. Pack Sizes: 1 mg. Product ID: HY-126708. | |
| Lulizumab | Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is an anti-CD28 domain antibody antagonist. Lulizumab inhibits T-cell activation by selectively targeting the CD28 signal. In a sensitized non-human primate kidney transplantation model, when combined with Carfilzomib (HY-10455), Lulizumab can regulate immune cells and prolong the survival time of the graft[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-931699 Antibody. CAS No. 2235419-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99302. | |
| Lumacaftor | Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-809; VRT 826809. CAS No. 936727-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13262. | |
| Lumacaftor-d4 | Lumacaftor-d4 is the deuterium labeled Lumacaftor (HY-13262)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-809-d4; VRT 826809-d4. CAS No. 2733561-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13262S. | |
| Lumasiran | Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALN-G01. CAS No. 1834610-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132588. | |
| Lumasiran sodium | Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1834612-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132613. | |
| Lumateperone | Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITI-007. CAS No. 313368-91-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17637. | |
| Lumateperone metabolite 1 | Lumateperone metabolite 1 (Formula T) is a metabolite of Lumateperone (HY-17637)[1]. Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1469777-40-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164703. | |
| Lumateperone tosylate | Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITI-007 tosylate. CAS No. 1187020-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19733. | |
| Lumefantrine | Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Benflumetol. CAS No. 82186-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0803. | |
| Lumichrome | Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1086-80-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-115385. | |
| Lumicitabine | Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALS-008176; ALS-8176. CAS No. 1445385-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12983A. | |
| Lumiflavin | Lumiflavin (Lumiflavine), a riboflavine analog, causes significant inhibition of riboflavine uptake. Lumiflavin can effectively reduce the riboflavin enrichment in cancer stem-like cells (CSCs) and sensitize the effect of cisplatin Diamminedichloroplatinum (DDP) on CSCs. Lumiflavin is promising for research of ovarian cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lumiflavine. CAS No. 1088-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-121608. | |
| Lumiliximab | Lumiliximab (Anti-CD23 Recombinant Antibody) is an anti-CD23 monoclonal antibody that inhibits allergen-induced responses[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: Gomiliximab; IDEC-152; ST-152. CAS No. 357613-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99303. | |
| Luminespib | Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VER-52296; AUY922; NVP-AUY922. CAS No. 747412-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10215. | |
| Luminol | Luminol is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λmax. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diogenes reagent. CAS No. 521-31-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-15922. | |
| Luminol sodium salt | Luminol sodium salt is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol sodium salt exhibits chemiluminescence (CL) at 425 nm λmax. Luminol sodium salt is commonly used in forensics as a diagnostic tool for the detection of blood stains[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20666-12-0. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15922A. | |
| Lumisterol | Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9β,10α-Ergosterol. CAS No. 474-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0181A. | |
| Lumisterol 3 (purity>90%) | Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C. CAS No. 5226-1-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112023. | |
| Lumistobart | HY-P990926 is an SIRPA-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: BR-105. CAS No. 2851923-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990926. | |
| Lumogallion | Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4386-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-137296. | |
| Lumretuzumab | Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 (ERBB3) monoclonal antibody. Lumretuzumab effectively inhibits the activity of key oncogenic signaling pathways such as PI3K/AKT and MAPK. Lumretuzumab has been optimized through glycosyl engineering to enhance antibody-dependent cell-mediated cytotoxicity (ADCC). Lumretuzumab can be used to study HER3-positive, HER2-low-expressing solid tumors, especially breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human ERBB3 Recombinant Antibody. CAS No. 1448327-63-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99304. | |
| LUNA18 | LUNA18 is an orally-available cyclic peptide KRAS and ERK inhibitor. LUNA18 phosphorylates ERK and AKT and decreases cell proliferation in RAS-mutated cancer cells. LUNA18 exhibits RAS signal inhibition and potent anti-cancer activities through inhibiting interaction between RAS and guanine nucleotide exchange factors (GEFs) in a mouse xenograft model. LUNA18 shows significant cellular efficacy against cell lines with KRAS genetic alterations, such as colon cancer, stomach cancer, non-small cell lung cancer and pancreaticcancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Paluratide. CAS No. 2676177-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156002. | |
| Lunasin | Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 496823-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5285. | |
| lunresertib | lunresertib (RP-6306) is a potent, selective and orally active PKMYT1 inhibitor with an IC50 of 14 nM. lunresertib shows a high degree of selectivity over other kinases in cellular binding assays. lunresertib shows anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RP-6306. CAS No. 2719793-90-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145817A. | |
| Lunsekimig | Lunsekimig (SAR443765) is an anti-TSLP/IL13/ALB nonobody composed of 5 sequentially linked variable region heavy chains. Lunsekimig decreases blood eosinophils and lowers plasma levels of IL-5, eotaxin-3, and IgE. Lunsekimig also improves lung function. Lunsekimig can be used for the study and treatment of type 2 inflammatory asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR443765. CAS No. 2770858-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990748. | |
| Lunularin | Lunularin is an inhibitor of 11β-hydroxysteroid dehydrogenase 1, with an IC50 of 45.44 μM and a Ki of 35.8 μM against human 11β-HSD1, and an IC50 of 17.39 μM and a Ki of 10.31 μM against rat 11β-HSD1. Lunularin upregulates the transcription levels of Sirt1 and Hmox1 genes in the liver. Lunularin reduces food intake and body weight gain, and decreases blood glucose levels in mice fed a high-fat diet. Lunularin inhibits LPS-induced TLR4-mediated NF-κB pathway activation and nitric oxide production. Lunularin inhibits the proliferation and colony formation of renal cancer and colon cancer cells, and exhibits cancer cell-specific cytotoxicity. Lunularin binds to the steroid-binding site of human 11β-HSD1 and the steroid/NADPH-binding region of rat 11β-HSD1, but does not inhibit 11β-HSD2 or mouse 11β-HSD1. Lunularin can be used in research related to diet-induced obesity, renal cancer, colorectal cancer, inflammatory diseases and metabolic syndrome[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37116-80-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124529. | |
| Lupanine | Lupanine (D-Lupanine) is a natural ketonic derivative of Sparteine (HY-W008350) with a ganglioplegic activity. Lupanine shows binding affinity for nicotinic receptor with a Ki value of 500 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Lupanine. CAS No. 550-90-3. Pack Sizes: 1 mg. Product ID: HY-N3359. | |
| Lupartumab | Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used for the synthesis of antibody-drug conjugate BAY 1129980[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 1112623. CAS No. 1640971-88-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99718. | |
| Lupeol | Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Clerodol; Monogynol B; Fagarasterol. CAS No. 545-47-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0790. | |
| Lupeol acetate | Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1617-68-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126114. | |
| (-)-Lupinine | (-)-Lupinine is an alkaloid and membrane fusion inhibitor. (-)-Lupinine does not affect the synthesis of proinflammatory cytokines during the host response to Serratia proteamaculans infection. (-)-Lupinine can enhance the expression of the bacterial surface protein OmpX. (-)-Lupinine can be used for research on bacterial infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 486-70-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121219. | |
| Lupiwighteone | Lupiwighteone is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 8-prenylgenistein. CAS No. 104691-86-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N3354. | |
| Lurasidone | Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM-13496. CAS No. 367514-87-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0032A. | |
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