MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Linoleic acid alkyne | Linoleic acid alkyne is an ω-alkyne derivative of Linoleic acid (HY-N0729). Linoleic acid alkyne can be used to synthesize other alkyne-containing products,such as glycerophospholipids, for click chemistry[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ω-Alkynyl linoleic acid. CAS No. 1219038-31-9. Pack Sizes: 100 μg (3.62 mM * 100 μL in Ethanol). Product ID: HY-145469. |  |
| Linoleic acid-d2 | Linoleic Acid-d2 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Deulinoleic acid. CAS No. 31447-29-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0729S5. | |
| Linoleic acid-d4 | Linoleic Acid-d4 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79050-23-0. Pack Sizes: 500 μg (17.58 mM * 99.98 μL in Methyl acetate). Product ID: HY-N0729S. | |
| Linoleic acid,suitable for cell culture | Linoleic acid is a critical component of polyunsaturated fatty acids. Linoleic acid reduces GSH-PX and T-SOD activities. Linoleic acid functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid can cause acute oxidative damage to red blood cells, ultimately leading to partial acute anemia. Linoleic acid can be used in the research of skin diseases associated with linoleic acid deficiency[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N0729D. | |
| Linoleoyl ethanolamide | Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1 (CB1) and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Linoleic acid monoethanolamide. CAS No. 68171-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-113421. | |
| Linopirdine | Linopirdine (DuP 996) is an orally active, selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor with an IC50 of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DuP 996. CAS No. 105431-72-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020468. | |
| Linperlisib | Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YY-20394. CAS No. 1702816-75-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102031. | |
| Linrodostat | Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 value of 1.1 nM in IDO1-HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986205; ONO-7701. CAS No. 1923833-60-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101560. | |
| Linsidomine hydrochloride | Linsidomine hydrochloride (SIN-1 chloride) is a spontaneous ROS/RNS generator and peroxynitrite donor. Linsidomine hydrochloride is a vasodilator and platelet aggregation inhibitor. Linsidomine hydrochloride induces oxidative stress-induced chondrocyte apoptosis and necrosis. Linsidomine hydrochloride inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of Linsidomine hydrochloride shows protective effects on Zn2+ treated nerve cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SIN-1 chloride. CAS No. 16142-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101200. | |
| Linsitinib | Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OSI-906. CAS No. 867160-71-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10191. | |
| Lintuzumab | Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SGN-33; HuM-195; GLK-33 Antibody. CAS No. 166089-32-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9983. | |
| Linustedastatum | Linustedastatum (Linustedastat; FOR-6219) is an orally active hydroxysteroid 17-beta dehydrogenase 1 (HSD17B1) inhibitor. Linustedastatum can be used for the study of endometriosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Linustedastat; FOR-6219; OG-6219. CAS No. 2254299-48-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159525. | |
| Linvemastat | Linvemastat (Compound FC-4) is an orally active MMP-12 inhibitor (IC50: < 10 ?nM) with high selectivity of MMP-1, -2, -3, -7, -9, -10 and -14. Linvemastat significantly attenuates lung fibrosis in Bleomycin (HY-108345) induced unilateral lung fibrosis mice model and potently reduces kidney damage, interstitial inflammation or fibrosis in kidney fibrosis model of unilateral ureteral occlusion. Linvemastat can be used for inflammatory diseases research, such as idiopathie pulmonary fibrosis (IPF), inflammatory bowel disease (IBD) and asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FP-020. CAS No. 2389060-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171804. | |
| Linvencorvir | Linvencorvir (RG7907) is an orally active Hepatitis B virus core protein allosteric modulator. Linvencorvir induces Apoptosis. Linvencorvir has antiviral activity against HBV[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG7907; RO7049389. CAS No. 1808248-05-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145579. | |
| Linvoseltamab | Linvoseltamab (REGN5458) is a bispecific T-cell engager (BiTE) antibody that specifically binds to B cell maturation antigen (BCMA) and CD3 of T cells, thereby directing T cells to multiple myeloma (MM) cells expressing BCMA and activating T cells to kill tumor cells. Linvoseltamab can be used in research of relapsed/refractory multiple myeloma (RRMM)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN5458. CAS No. 2408319-25-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9989. | |
| Liothyronine | Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with Kis of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3. CAS No. 6893-2-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-A0070A. | |
| Liothyronine (GMP) | Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Triiodothyronine (GMP); 3,3',5-Triiodo-L-thyronine (GMP); T3 (GMP). CAS No. 6893-2-3. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-A0070AG. | |
| Liothyronine sodium | Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium. CAS No. 55-06-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-A0070. | |
| Lipase,Candida antarctica (Immobilized) | Lipase,Candida antarctica (Immobilized) is an immobilized lipase isolated from Candida antarctica fraction B. Lipase,Candida antarctica (Immobilized) features high stability and selectivity. Lipase,Candida antarctica (Immobilized) is widely used in fields such as chemical synthesis, food oil modification, and biodiesel production[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-62-1. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-Y1422D. | |
| Lipid 15 | Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs). Uses: Scientific research. Category: Signaling pathways. CAS No. 2588111-36-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-153378. | |
| Lipid 16 | Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097638-11-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-159858. | |
| Lipid 20b | Lipid 20b is a thiophene ionizable cationic lipid. Lipid 20 b can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Lipid 20b can be studied in research for enhancing mRNA vaccine delivery and transfection efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2921586-65-2. Pack Sizes: 5 mg (70.51 mM * 100 μL in Ethanol); 10 mg (70.51 mM * 200 μL in Ethanol). Product ID: HY-176753. | |
| Lipid 29 | Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244716-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148648. | |
| Lipid 5 | Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089251-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138171. | |
| Lipid 6 | Lipid 6 is an ionizable amino lipid. Lipid 6 can be used to synthesize lipid nanoparticles. Lipid 6 can be used in RNA delivery research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226547-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150117. | |
| Lipid 8 | Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226547-25-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150118. | |
| Lipid 9 | Lipid 9 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2982842-90-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160512. | |
| Lipid A-11 | Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CICL1. CAS No. 2996998-09-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170333. | |
| LipidGreen 2 | LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1382764-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1353. | |
| Lipoamide | Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide. CAS No. 940-69-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1142. | |
| Lipofermata | Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 μM in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 μM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 297180-15-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-116788. | |
| Lipoic acid | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid. CAS No. 1200-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-18733. | |
| Lipoteichoic acid | Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56411-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9481. | |
| Lipoxamycin hemisulfate | Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11075-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119759A. | |
| Liproxstatin-1 | Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 950455-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12726. | |
| Liproxstatin-1 hydrochloride | Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250025-95-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12726A. | |
| Liquiritigenin | Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4',7-Dihydroxyflavanone. CAS No. 578-86-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0377. | |
| Lirafugratinib | Lirafugratinib (RLY-4008) is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC50 of 3 nM. Lirafugratinib covalently binds to Cys491. Lirafugratinib targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RLY-4008. CAS No. 2549174-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-147250. | |
| Lirafugratinib hydrochloride | Lirafugratinib (RLY-4008) hydrochloride is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC50 of 3 nM. Lirafugratinib hydrochloride covalently binds to Cys491. Lirafugratinib hydrochloride targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RLY-4008 hydrochloride. CAS No. 2688040-45-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250A. | |
| Liraglutide | Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. Uses: Scientific research. Category: Signaling pathways. CAS No. 204656-20-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0014. | |
| Lirentelimab | Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK002; Antolimab. CAS No. 2283348-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99371. | |
| Lirilumab | Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPH2102. CAS No. 1000676-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99208. | |
| Lisaftoclax | Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APG-2575; Bcl-2/Bcl-xl inhibitor 1. CAS No. 2180923-05-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129179. | |
| Lisavanbulin | Lisavanbulin (BAL-101553) is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin is a BBB-penetrant and orally active antitumor agent, especially in tumors that express high levels of end-binding protein 1. Lisavanbulin has ability to target tumor cell proliferation and affects the tumor microenvironment by reducing tumor microvasculature. Lisavanbulin is also a spindle assembly checkpoint activator. Lisavanbulin induces cell cycle arrest and subsequent death or aberrant chromosome segregation. Lisavanbulin can be studied in research for diffuse large B cell lymphoma (DLBCL) and glioblastoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAL-101553. CAS No. 1263384-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19916. | |
| Lisinopril | Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-521. CAS No. 76547-98-3. Pack Sizes: 10 mM * 1 mL in Water; 250 mg; 500 mg. Product ID: HY-18206. | |
| Lisinopril dihydrate | Lisinopri dihydrate (MK-521 dihydrate) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-521 dihydrate. CAS No. 83915-83-7. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-18206A. | |
| L-Isoleucine | L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73-32-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 50 g; 100 g. Product ID: HY-N0771. | |
| L-Isoleucine-1-13C | L-Isoleucine-1-13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 81202-01-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-N0771S4. | |
| L-Isoleucine-13C6 | L-Isoleucine-13C6 is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 201740-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S. | |
| L-Isoleucine-13C6,15N | L-Isoleucine-13C6,15N is 13C and 15N labeled L-isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 202468-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0771S9. | |
| L-Isoleucine-15N | L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59935-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0771S2. | |
| L-Isoleucine-d10 | L-Isoleucine-d10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 35045-71-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S3. | |
| L-Isovaline | L-Isovaline is a valine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 595-40-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g. Product ID: HY-W018850. | |
| Lisuride | Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18016-80-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12713. | |
| LIT-001 | LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2245072-21-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124733A. | |
| Lithium 3,5-diiodosalicylate | Lithium 3,5-diiodosalicylate is a compound used in the study of bipolar disorder and other psychiatric disorders. It contains lithium and a salicylate. Lithium 3,5-diiodosalicylate works by affecting the levels of certain neurotransmitters in the brain, including dopamine and serotonin. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3,5-Diiodosalicylic acid lithium salt. CAS No. 653-14-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W250174. | |
| Lithium acetate dihydrate | Lithium acetate dihydrate is a compound with a one-dimensional structure that has various applications in industries such as pharmaceuticals, ceramics, and research laboratories. Lithium acetate dihydrate is often used as a source of lithium ions in chemical reactions and as a precursor in the synthesis of other lithium compounds[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6108-17-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W094471. | |
| Lithium carbonate | Lithium carbonate (Carbolithium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbolithium; Lithium carbonate. CAS No. 554-13-2. Pack Sizes: 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-Y0292. | |
| Lithium chloride, 99% | Lithium chloride, for molecular biology, 99% can be used in the preparation of wash buffers for chromatin immunoprecipitation. Lithium chloride, for molecular biology, 99% is a kind of biological materials or organic compounds that are widely used in life science research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7447-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g. Product ID: HY-Y0649D. | |
| Lithium chloride, 99.3%-T | Lithium chloride, 99% (LiCl, Premium grade) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LiCl, Premium grade. CAS No. 7447-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-Y0649. | |
| Lithium chloride hydrate | Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hydrate/monohydrateortrihydrate. CAS No. 85144-11-2. Pack Sizes: 100 mg. Product ID: HY-W094474. | |
| Lithium dodecyl sulfate | Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate induces low surface viscosity; it forms micelles in aqueous solutions through entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate exhibits cloud point behavior due to micelle aggregation and phase separation. Lithium dodecyl sulfate can form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule, and it has higher equilibrium surface tension and foamability compared to other dodecyl sulfate counterion variants. The foam stability of Lithium dodecyl sulfate above its critical micelle concentration is low, and its dynamic surface tension pattern changes dynamically with bubble frequency[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2044-56-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-W099535. | |
| Lith-O-Asp | Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 881179-02-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112415. | |
| Lithocholic acid | Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist[1][2][3][4][5]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 3α-Hydroxy-5β-cholanic acid. CAS No. 434-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0172. | |
| Lithocholic acid 3-sulfate disodium | Lithocholic acid 3-sulfate disodium is a GPR39 agonist, with EC50 values of 41 μM and 42.4 μM in M39-20 and hGPR39-2 cells, respectively, in the absence of Zn2+, and 0.88 μM and 0.97 μM in the presence of Zn2+. Lithocholic acid 3-sulfate disodium acts as a RORγt ligand. Lithocholic acid 3-sulfate disodium stimulates the GPR39 receptor to initiate intracellular calcium signaling, independent of the Zn2+-binding sites H17 and H19. LCA-3-S selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate disodium can be used in the research of cholestatic liver diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfolithocholic acid disodium; LCAS disodium. CAS No. 64936-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113238A. | |
| Lithocholic acid-d4 | Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3α-Hydroxy-5β-cholanic acid-d4. CAS No. 83701-16-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0172S. | |
| Lithocholic acid (Standard) | Lithocholic acid (Standard) is the analytical standard of Lithocholic acid. This product is intended for research and analytical applications. Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3α-Hydroxy-5β-cholanic acid (Standard). CAS No. 434-13-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0172R. | |
| Lithospermic acid | Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Lithospermic acid. CAS No. 28831-65-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0823. | |
| Litifilimab | Litifilimab (BIIB059) is a humanized anti-BDCA2 IgG1 monoclonal antibody administered subcutaneously. Litifilimab can inhibit the production of type I interferons, cytokines and chemokines. Litifilimab can be used in the research of diseases such as systemic lupus erythematosus[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIIB059. CAS No. 2407378-48-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9990. | |
| Litorin | Litorin, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55749-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103281. | |
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