MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Livmoniplimab | Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-151; ARGX-115. CAS No. 2412004-88-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99708. |  |
| Lixisenatide | Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 320367-13-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0119. | |
| Lixisenatide acetate | Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide acetate inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide acetate can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide acetate can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1997361-87-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0119A. | |
| Lixivaptan | Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VPA-985; WAY-VPA 985. CAS No. 168079-32-1. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14185. | |
| Lixudebart | Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALE.F02. CAS No. 2749515-10-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990045. | |
| Lixumistat | Lixumistat (IM156 free base) is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IM156 free base; HL156A free base; HL271 free base. CAS No. 1422365-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136093B. | |
| Lixumistat acetate | Lixumistat (IM156) acetate is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat acetate strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat acetate exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IM156; HL156A; HL271 acetate. CAS No. 1422365-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136093A. | |
| Lixumistat hydrochloride | Lixumistat (IM156) hydrochloride is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat hydrochloride strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat hydrochloride exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HL271; IM156 hydrochloride; HL156A hydrochloride. CAS No. 1422365-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-136093. | |
| LJ001 | LJ001 is a broad-spectrum and orally active antiviral agent. LJ001 exerts antiviral activities by binding to viral membranes. LJ001 inhibits TGEV and PDCoV infection. LJ001 decreases TGEV N and PDCoV N-protein expression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851305-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16957. | |
| LJH685 | LJH685 is a potent, ATP-competitive and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50s of 6, 5, 4 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627710-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19712. | |
| LJI308 | LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627709-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19713. | |
| LK-2 | LK-2 is an antagonist for ASIC1a with a Kd of 1.9 μM. LK-2 reduces glutamate-induced ASIC1a current-enhancement with an IC50 of 6.6 μM. LK-2 exhibits neuroprotective efficacy in mouse ischemic stroke model, with improved motor and coordination skills. LK-2 is blood-brain barrier (BBB) penetrable[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2649762-09-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164284. | |
| LK-60 | LK-60 is a potent DprE1 inhibitor. LK-60 effectively inhibits the proliferation of Mycobacterium tuberculosis. LK-60 has good safety profiles to gut microbiota and human cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033267-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161178. | |
| LK 614 | LK 614 is a membrane permeable iron chelator that can be used to study the protective effects against L-Histidine (HY-N0832)-induced cell damage[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 82461-57-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126164. | |
| LKBtide | LKBtide is a biological active peptide. (This is a peptide substrate that is phosphorylated by Serine/Threonine kinase 11 (STK11), also known as LKB1. LKBtide is derived from sucrose non-fermenting 1 (SNF1) protein kinase, which is normally activated by the LKB1/AMP-activated protein kinase (AMPK) signaling pathway.). Uses: Scientific research. Category: Signaling pathways. CAS No. 835653-81-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P5435. | |
| L-Kynurenine | L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922-83-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-104026. | |
| L-Kynurenine-d4 | L-Kynurenine-d4 is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2672568-86-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-104026S. | |
| L-Kynurenine (Standard) | L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922-83-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104026R. | |
| LL-37, human | LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154947-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1222. | |
| L-Lactate Dehydrogenase, rabbit muscle | L-Lactate Dehydrogenase, rabbit muscle is a biological material or organic compound that can be used in life science research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-60-9. Pack Sizes: 2.5 KU; 25 KU. Product ID: HY-P2807I. | |
| L-Lactic acid | L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Hydroxypropanoic acid. CAS No. 79-33-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-Y0479. | |
| L-Lactic acid-13C3 | L-Lactic acid-13C3 is a 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid-13C3 can be used for lactate metabolism research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-hydroxypropanoic-13-C3. CAS No. 87684-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-Y0479S. | |
| L-Lactic acid-13C3 sodium (20% w/w in water) | L-Lactic acid-13C3 ((S)-2-hydroxypropanoic-13C3) sodium (20% in water) is the 13C labeled L-Lactic acid. L-Lactic acid-13C3 sodium (20% in water) can be used for lactate metabolism research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-hydroxypropanoic-13-C3 sodium (20% w/w in water). CAS No. 201595-71-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-Y0479AS. | |
| L-Lactic acid-d3 sodium | Sodium (S)-2-hydroxypropanoate-d3 is the deuterium labeled Sodium (S)-2-hydroxypropanoate[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Hydroxypropanoic acid-d3 sodium. CAS No. 285979-84-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W040233S. | |
| L-Lactic acid sodium | L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-2-Hydroxypropanoic acid sodium. CAS No. 867-56-1. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-W040233. | |
| LLC0424 | LLC0424 is a potent and selective cereblon-based PROTAC nuclear receptor-binding SET domain-containing 2 (NSD2) degrader. LLC0424 effectively degraded NSD2 with a DC50 of 20 nM in RPMI-8402 cells. LLC0424 selectively induces NSD2 degradation in a cereblon- and proteasome-dependent fashion. (Blue: CRBN ligand (HY-14658), Black: linker (HY-40002); Pink: NSD2 inhibitor (HY-161575))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3061315-33-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-161574. | |
| L,L-Dityrosine | L,L-Dityrosine (o,o'-Dityrosine) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: o,o'-Dityrosine. CAS No. 63442-81-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101552A. | |
| L-Leucine | L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Leucine. CAS No. 61-90-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 500 mg. Product ID: HY-N0486. | |
| L-Leucine-13C | L-Leucine-13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 74292-94-7. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S1. | |
| L-Leucine-13C6 | Leucine-13C6 is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201740-84-3. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-N0486S2. | |
| L-Leucine-13C6,15N | L-Leucine-13C6,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202406-52-8. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-N0486S8. | |
| L-Leucine-15N | L-Leucine-15N is the 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59935-31-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S3. | |
| L-Leucine-18O2 | L-Leucine-18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73579-45-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S10. | |
| L-Leucine-2-13C,15N | L-Leucine-2-13C,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 285977-88-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S6. | |
| L-Leucine-7-amido-4-methylcoumarin hydrochloride | L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Leu-AMC hydrochloride. CAS No. 62480-44-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-137844. | |
| L-Leucine-d10 | L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106972-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S. | |
| L-Leucine-d2 | L-Leucine-d2 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 362049-59-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0486S12. | |
| L-Leucine-d3 | L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 87828-86-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S9. | |
| L-Leucyl-L-Leucine methyl ester hydrobromide | L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide. CAS No. 16689-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129905A. | |
| L-Leucyl-L-Leucine methyl ester hydrochloride | L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride. CAS No. 6491-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-129905. | |
| LL-K12-18 | LL-K12-18 is a CDK12 kinase inhibitor and a dual-site molecular glue. LL-K12-18 inhibits human CDK12 with an IC50 value of 283.9 nM, and selectively degrades cyclin K via the ubiquitin-proteasome system by stabilizing the CDK12-DDB1 complex. LL-K12-18 downregulates DNA damage response genes, reduces the phosphorylation level of CTD Ser2 in RNA polymerase II, and modulates biomarkers such as ATM, RAD51, γ-H2AX and cleaved PARP, thereby effectively inducing apoptosis and inhibiting proliferation of breast cancer cells. LL-K12-18 exhibits high target selectivity and serves as a research tool for studies on triple-negative breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3081311-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163944. | |
| LLK203 | LLK203 is a potent USP2/USP8 dual-target inhibitor with IC50s of 0.89 μM and 0.52 μM, respectively. LLK203 leads a degradation of ERα and induces apoptosis of breast cancer MCF-7 cells. LLK203 demonstrates antitumor activities against the 4T1 tumor mice model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758090-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162312. | |
| LLL12 | LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. LLL12 enhanced the inhibitory effect of Cisplatin (HY-17394) and Paclitaxel (HY-B0015) on ovarian cancer cell formation, migration, and growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1260247-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-19536. | |
| LLY-283 | LLY-283, a chemical probe, is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2040291-27-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107777. | |
| LLY-284 | LLY-284 is the diastereomer of LLY-283 with much less active. LLY-283 is a potent inhibitor of PRMT5. LLY-284 has the potential for the research of cancer diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226515-75-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107777A. | |
| LLY-507 | LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1793053-37-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19313. | |
| L-Lysine | L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-87-1. Pack Sizes: 10 mM * 1 mL in Water; 500 mg. Product ID: HY-N0469. | |
| L-Lysine-13C6,15N2 dihydrochloride | L-Lysine-13C6,15N2 (dihydrochloride) is a 15N-labeled and 13C-labled L-Lysine dihydrochloride[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202406-54-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009762S. | |
| L-Lysine-13C6,15N2 hydrochloride | L-Lysine-13C6,15N2 (hydrochloride) is the 13C- and 15N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Category: Signaling pathways. CAS No. 1200447-00-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0470S3. | |
| L-Lysine-13C6 hydrochloride | L-Lysine-13C6 hydrochloride is the 13C labeled L-Lysine hydrochloride[1]. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health[2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228077-86-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0470S8. | |
| L-Lysine-d4 hydrochloride | L-Lysine-d4 (hydrochloride) is the deuterium labeled L-Lysine. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Category: Signaling pathways. CAS No. 284664-96-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0470S6. | |
| L-Lysine hydrate | L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39665-12-8. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 50 g. Product ID: HY-W015370. | |
| L-Lysine hydrochloride | L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Category: Signaling pathways. CAS No. 657-27-2. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0470. | |
| LM11A-31 | LM11A-31, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102562-74-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117088. | |
| LM11A-31 dihydrochloride | LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1243259-19-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110155. | |
| LM22A-4 | LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research. Uses: Scientific research. Category: Signaling pathways. CAS No. 37988-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100673. | |
| LM22B-10 | LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo. Uses: Scientific research. Category: Signaling pathways. CAS No. 342777-54-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104047. | |
| LM2I | LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055494-50-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156112. | |
| L-Methionine | L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63-68-3. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-N0326. | |
| L-Methionine-13C | L-Methionine-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 49705-26-2. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-N0326S3. | |
| L-Methionine-13C5 | L-Methionine-13C5 is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 202326-57-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0326S5. | |
| L-Methionine-13C5,15N | L-Methionine-13C5,15N is the 13C- and 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 202468-47-1. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-N0326S6. | |
| L-Methionine-15N | L-Methionine-15N is the 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 82572-25-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0326S. | |
| L-Methionine-d3 | L-Methionine-d3 is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 13010-53-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0326S7. | |
| L-Methionine-d4 | L-Methionine-d4 is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Category: Signaling pathways. CAS No. 67866-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0326S10. | |
| L-Methionine-DL-sulfoximine | L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSX; MSO. CAS No. 15985-39-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1692. | |
| L-Methionine p-nitroanilide | L-Methionine p-nitroanilide is a Methionine (HY-13694) derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6042-4-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-W141962. | |
| LMK-235 | LMK-235 is a potent and selective HDAC4/5 inhibitor, inhibits HDAC5, HDAC4, HDAC6, HDAC1, HDAC2, HDAC11 and HDAC8, with IC50s of 4.22 nM, 11.9 nM, 55.7 nM, 320 nM, 881 nM, 852 nM and 1278 nM, respectively, and is used in cancer research. Uses: Scientific research. Category: Signaling pathways. CAS No. 1418033-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18998. | |
| LMP517 | LMP517 (NSC 781517) is a potent and non-camptothecin Topoisomerase I and II (TOP1 and TOP2) dual inhibitor. LMP517 can induce TOP1 and TOP2 cleavage complexes (TOP1ccs and TOP2ccs). LMP517 can induce cancer cells DNA damage and γH2AX production. LMP517 can be used for the research of cancer, such as small cell lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 781517. CAS No. 1883730-99-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160005. | |
| LMT-28 | LMT-28 is an orally active and the first synthetic IL-6 inhibitor that functions through direct binding to gp130. LMT-28 shows low toxicity and selectively inhibits IL-6-induced phosphorylation of STAT3, JAK2, and gp130[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1239600-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102084. | |
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