MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Lenalidomide hemihydrate | Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-5013 hemihydrate. CAS No. 847871-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-A0003B. |  |
| Lenalidomide (Standard) | Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-5013 (Standard). CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R. | |
| Leniolisib | Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor. Leniolisib has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDZ173. CAS No. 1354690-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17635. | |
| Leniolisib phosphate | Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. Leniolisib phosphate has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDZ173 phosphate. CAS No. 1354691-97-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17635A. | |
| Lentinan | Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering[1][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37339-90-5. Pack Sizes: 100 mg. Product ID: HY-N6653. | |
| Lenumlostat | PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAT-1251; GB2064. CAS No. 2007885-39-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-107422. | |
| Lenvatinib | Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7080. CAS No. 417716-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10981. | |
| Lenvatinib mesylate | Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7080 mesylate. CAS No. 857890-39-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10981A. | |
| Lenvatinib (Standard) | Lenvatinib (Standard) is the analytical standard of Lenvatinib. This product is intended for research and analytical applications. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7080 (Standard). CAS No. 417716-92-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10981R. | |
| Lenzilumab | Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KB 003. CAS No. 1229575-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99207. | |
| Leptin (22-56), human | Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs). Uses: Scientific research. Category: Signaling pathways. CAS No. 183598-56-3. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1523. | |
| Leptomycin B | Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-16909. | |
| LEQ803 | LEQ803 (N-Desmethyl Ribociclib) is a drug metabolite of the CDK4/6 inhibitor Ribociclib (HY-15777), which is produced through metabolism by CYP3A4. LEQ803 has potential application value in the field of oncology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Desmethyl Ribociclib. CAS No. 1211441-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171459. | |
| Lercanidipine | Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612. | |
| Leriglitazone | Leriglitazone (MIN-102; Hydroxypioglitazone) is an orally active and a BBB-penetrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MIN-102; Hydroxypioglitazone. CAS No. 146062-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117727. | |
| Leriglitazone hydrochloride | Leriglitazone (MIN-102; Hydroxypioglitazone) hydrochloride is an orally active and a BBB-penetrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone hydrochloride, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone hydrochloride can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MIN-102 hydrochloride; Hydroxypioglitazone hydrochloride. CAS No. 146062-46-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117727A. | |
| Leritrelvir | Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a Ki of 8.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAY1216. CAS No. 2923310-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153121. | |
| Lerociclib | Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G1T38. CAS No. 1628256-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112272. | |
| Lerociclib dihydrochloride | Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G1T38 dihydrochloride. CAS No. 2097938-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112272A. | |
| Leronlimab | Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRO 140. CAS No. 674782-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99697. | |
| Lesogaberan hydrochloride | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptor. The affinity (Kis) of Lesogaberan hydrochloride for rat GABAB and GABAA receptors, as measured by displacement of [3H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-3355 hydrochloride. CAS No. 2925644-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-10061B. | |
| Lestaurtinib | Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CEP-701; KT-5555. CAS No. 111358-88-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-50867. | |
| Letermovir | Letermovir (AIC246) is a potent inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AIC246; MK-8228. CAS No. 917389-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15233. | |
| L-Ethionine | L-Ethionine (L-ETH) is aamino acids and their derivatives. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-ETH. CAS No. 13073-35-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W017200. | |
| Letolizumab | Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986004. CAS No. 1450981-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99701. | |
| Letrozole | Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGS 20267. CAS No. 112809-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-14248. | |
| [Leu15]-Gastrin I (human) | [Leu15]-Gastrin I (human) is a Gastrin I, human (HY-P1097) peptide hormone derivative, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39024-57-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2671. | |
| [Leu31,Pro34]-Neuropeptide Y (porcine) | [Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 125580-28-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0208. | |
| [Leu5]-Enkephalin | [Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin. CAS No. 58822-25-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0288. | |
| Leu-AMS | Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 288591-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-108900. | |
| Leucettine L41 | Leucettine L41 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) and CDC-like kinases (CLKs). Leucettine L41 can also inhibit GSK-3 singnaling. Leucettine L41 can inhibit cell apoptosis and ROS production. Leucettine L41 can promote β-cell cell cycle progression, cell proliferation and increase insulin secretion. Leucettine L41 can be used for the researches of neurological disease and metabolic disease, such as Alzheimers disease (AD) and diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1112978-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-117049. | |
| Leucettinib-92 | Leucettinib-92 (compound 92) is an inhibitor of DYRK/CLK kinase, The IC50s are 147 nM (CLK1), 39 nM (CLK2), 5.2 nM (CLK4), 0.8 μM (CLK3), 124 nM (DYRK1A), 204 nM (DYRK1B), 0.16 μM (DYRK2), respectively. 1.0 μM (DYRK3), 0.52 μM (DYRK4), 2.78 μM (GSK3)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2732859-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155723. | |
| Leucocyanidin | Leucocyanidin is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models[1]. Uses: Scientific research. Category: Natural products. CAS No. 480-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-119580. | |
| Leucomethylene blue mesylate | Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRx0237 mesylate; Methylene blue leuco base mesylate. CAS No. 1236208-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19948. | |
| Leucomycin | Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Kitasamycin. CAS No. 1392-21-8. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-N7112. | |
| Leucyl-phenylalanine | Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides. Uses: Scientific research. Category: Signaling pathways. CAS No. 3063-5-6. Pack Sizes: 10 mM * 1 mL in Water; 50 mg. Product ID: HY-113278. | |
| Leucylproline | Leucylproline, a dipeptide, plays important roles in the medium-dependent regulation of proteinase activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6403-35-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114729. | |
| Leukadherin-1 | Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 344897-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15701. | |
| Leukotriene B4 | Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LTB4; 5(S),12(R)-DiHETE. CAS No. 71160-24-2. Pack Sizes: 25 μg (297.2 μM * 250 μL in Ethanol). Product ID: HY-107608. | |
| Leukotriene B4-d4 | Leukotriene B4-d4 is the deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LTB4-d4; 5(S),12(R)-DiHETE-d4. CAS No. 124629-74-9. Pack Sizes: 10 μg (293.69 μM * 100 μL in Acetonitrile); 25 μg (293.69 μM * 250 μL in Acetonitrile). Product ID: HY-107608S. | |
| Leukotriene C4 | Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 72025-60-6. Pack Sizes: 25 μg (159.8 μM * 250 μL in Ethanol). Product ID: HY-113446. | |
| Leukotriene C4-d5 | Leukotriene C4-d5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Uses: Scientific research. Category: Signaling pathways. CAS No. 1441421-73-3. Pack Sizes: 25 μg (158.53 μM * 250 μL in Ethanol); 1 mg; 5 mg. Product ID: HY-113446S. | |
| Leukotriene D4 | Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73836-78-9. Pack Sizes: 10 μg (201.34 μM * 100 μL in Ethanol); 50 μg (201.34 μM * 500 μL in Ethanol). Product ID: HY-113456. | |
| Leukotriene E4 | Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LTE4. CAS No. 75715-89-8. Pack Sizes: 25 μg (227.47 μM * 250 μL in Ethanol); 50 μg (227.47 μM * 500 μL in Ethanol); 100 μg (227.47 μM * 1 mL in Ethanol). Product ID: HY-113465. | |
| Leukotriene E4-d5 | Leukotriene E4-d5 is the deuterium labeled Leukotriene E4. Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LTE4-d5. CAS No. 1240398-14-4. Pack Sizes: 25 μg (224.90 μM * 250 μL in Ethanol). Product ID: HY-113465S. | |
| Leu-Leu-OH | Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Leucyl-L-leucine; Leu-Leu; H-Leu-Leu-OH. CAS No. 3303-31-9. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-W008642. | |
| Leupeptin Ac-LL hydrochloride | Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24125-16-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18234C. | |
| Leupeptin hemisulfate | Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits Mpro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103476-89-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18234A. | |
| Levacetylleucine | Levacetylleucine (N-acetyl-L-leucine), an orally bioavailable and brain-penetrant compound, is an acetylated derivative of amino acid Leucine. Levacetylleucine is the active form of N-acetyl-leucine (NAL). Levacetylleucine attenuates neuronal death and neuroinflammation in the cortical tissue of mice. Levacetylleucine also potentially improves ameliorates lysosomal and metabolic dysfunction. Levacetylleucine improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats. Levacetylleucine is promising for research of neurological manifestations of Niemann-Pick disease type C, traumatic brain injury and neurodegeneration prevention[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetyl-L-leucine. CAS No. 1188-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-59291. | |
| Levalbuterol hydrochloride | Levalbuterol ((R)-Albuterol) hydrochloride is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol hydrochloride is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Albuterol hydrochloride; (R)-Salbutamol hydrochloride; Levosalbutamol hydrochloride. CAS No. 50293-90-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1675A. | |
| Levalbuterol hydrochloride (Standard) | Levalbuterol (hydrochloride) (Standard) is the analytical standard of Levalbuterol (hydrochloride). This product is intended for research and analytical applications. Levalbuterol ((R)-Albuterol) hydrochloride is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol hydrochloride is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Albuterol hydrochloride (Standard); (R)-Salbutamol hydrochloride (Standard); Levosalbutamol hydrochloride (Standard). CAS No. 50293-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1675AR. | |
| Levamisole | Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Tetramisole. CAS No. 14769-73-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0106. | |
| Levamisole-d5 hydrochloride | Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Tetramisole-d5 hydrochloride. CAS No. 1246819-64-6. Pack Sizes: 1 mg. Product ID: HY-13666S. | |
| Levamisole hydrochloride | Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Tetramisole hydrochloride. CAS No. 16595-80-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-13666. | |
| Levamisole hydrochloride (Standard) | Levamisole (hydrochloride) (Standard) is the analytical standard of Levamisole (hydrochloride). This product is intended for research and analytical applications. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Tetramisole hydrochloride (Standard). CAS No. 16595-80-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-13666R. | |
| Levamlodipine | Levamlodipine ((S)-Amlodipine; Levoamlodipin) is an orally active L-type calcium channel blocker and MMP-9 modulator with high permeability and retention properties. Levamlodipine significantly enhances plaque stability and improves lipid profiles by reducing blood pressure, decreasing systolic blood pressure variability, and inhibiting MMP-9 expression in atherosclerotic plaques. Levamlodipine not only alleviates cardiac and aortic hypertrophy and prevents renal atrophy, but also produces synergistic effects in blood pressure reduction and organ protection when combined with bisoprolol (HY-129029). Levamlodipine exerts no significant inhibitory effect on abdominal aortic intimal hyperplasia. When excessively accumulated in the epidermis, Levamlodipine may induce changes in keratin structure, impair the skin barrier and trigger inflammation; long-term use further exacerbates skin irritation caused by local administration. Levamlodipine can be used in research related to hypertension and atherosclerosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Amlodipine; Levoamlodipine. CAS No. 103129-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14744. | |
| Levamlodipine besylate | Levamlodipine ((S)-Amlodipine; Levoamlodipin) besylate is an orally active L-type calcium channel blocker and MMP-9 modulator with high permeability and retention properties. Levamlodipine besylate significantly enhances plaque stability and improves lipid profiles by reducing blood pressure, decreasing systolic blood pressure variability, and inhibiting MMP-9 expression in atherosclerotic plaques. Levamlodipine besylate not only alleviates cardiac and aortic hypertrophy and prevents renal atrophy, but also produces synergistic effects in blood pressure reduction and organ protection when combined with bisoprolol (HY-129029). Levamlodipine besylate exerts no significant inhibitory effect on abdominal aortic intimal hyperplasia. When excessively accumulated in the epidermis, Levamlodipine besylate may induce changes in keratin structure, impair the skin barrier and trigger inflammation; long-term use further exacerbates skin irritation caused by local administration. Levamlodipine besylate can be used in research related to hypertension and atherosclerosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Amlodipine besylate; Levoamlodipine besylate. CAS No. 150566-71-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14744A. | |
| Levanase | Levanase is a slime-dissolving enzyme of Rhodotorula species. Levanase performs random hydrolysis of β-2,6 fructofuranosyl linkages in β-2,6 fructans containing more than 3 fructose units[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9041-11-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-E70011. | |
| Levcromakalim | Levcromakalim ((-)-Cromakalim) is an ATP-sensitive K+ channel (KATP) activator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Cromakalim; BRL 38227. CAS No. 94535-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14255. | |
| Levetiracetam | Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB L059. CAS No. 102767-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-B0106. | |
| Levetiracetam impurity 1 | Levetiracetam impurity 1 is an impurity of Levetiracetam (HY-B0106). Uses: Scientific research. Category: Signaling pathways. CAS No. 102849-49-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-135321. | |
| Levobunolol hydrochloride | Levobunolol (l-Bunolol) hydrochloride is a non-selective β-adrenergic antagonist and vasodilator. By blocking calcium ion influx and reducing the sensitivity of vascular smooth muscle to calcium, Levobunolol hydrochloride effectively dilates the ciliary arteries and increases ocular blood flow, so it is widely used in research on glaucoma and ocular hypertension. Levobunolol hydrochloride inhibits the β-receptor signaling pathway and the expression of related proliferation markers (such as CK3, CK14, CK19, Ki67) in corneal cells. In rabbit models, Levobunolol hydrochloride not only does not inhibit corneal epithelial regeneration, but also accelerates the healing of mechanical injury without adverse effects. Levobunolol hydrochloride also inhibits histamine-induced vasoconstriction and intracellular calcium elevation, exhibiting unique vascular regulatory activity. Levobunolol hydrochloride protects ocular blood flow and promotes corneal repair[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: l-Bunolol hydrochloride. CAS No. 27912-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1035. | |
| Levocabastine hydrochloride | Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R 50547 hydrochloride. CAS No. 79547-78-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14277A. | |
| Levocetirizine | Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Cetirizine. CAS No. 130018-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0814. | |
| Levocetirizine dihydrochloride | Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Levocetirizine dihydrochloride is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine dihydrochloride has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Cetirizine dihydrochloride. CAS No. 130018-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-W010841. | |
| Levodropropizine (Standard) | Levodropropizine (Standard) is the analytical standard of Levodropropizine. This product is intended for research and analytical applications. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-(-)-Dropropizine (Standard); DF-526 (Standard). CAS No. 99291-25-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1895R. | |
| Levofloxacin | Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity[1][2][3][4][5]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: (-)-Ofloxacin. CAS No. 100986-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 5 g. Product ID: HY-B0330. | |
| Levofloxacin-d8 | Levofloxacin-d8 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Ofloxacin-d8. CAS No. 1217716-71-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0330S. | |
| Levofloxacin hydrate | Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrate shows anti-orthopoxvirus activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Levofloxacin hemihydrate. CAS No. 138199-71-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 5 g. Product ID: HY-B0330A. | |
| Levofloxacin hydrochloride | Levofloxacin hydrochloride is an orally active antibiotic. Levofloxacin inhibits DNA gyrase and topoisomerase IV activity, inducing Apoptosis. Levofloxacin hydrochloride has antibacterial activity against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride exhibits anticancer activity against lung cancer. Levofloxacin hydrochloride has anti-acnegenic, anxiogenic, and analgesic effects. Levofloxacin hydrochloride shortens sleep duration in mice. Levofloxacin hydrochloride can be used in the research of infectious diseases (such as tuberculosis, chronic periodontitis, bacterial infections associated with stable COPD, and BK viremia) and lung cancer[1][2][3][4][5][6][7][8][9][10]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Ofloxacin hydrochloride. CAS No. 177325-13-2. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g. Product ID: HY-B0330B. | |
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