MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| L748337 | L748337 is a potent β3-adrenergic receptor antagonist and displays selectivity over β1 and β2 receptors. The Ki values of L748337 for β3-, β2- and β1-adrenoceptors are 4.0 nM, 204 nM and 390 nM, respectively[1]. L748337 couples predominantly to Gi to activate MAPK signaling and increases phosphorylation of Erk1/2 with pEC50 value of 11.6[2]. L748337 can be used for the research of cancer, nonalcoholic fatty liver disease (NAFLD), and cardiovascular related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 244192-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103211. |  |
| L755507 | L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 159182-43-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-19334. | |
| L-778123 | L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC50s of 2 nM and 98 nM respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183499-57-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16273. | |
| L-778123 hydrochloride | L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 253863-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16273A. | |
| L-796778 acetate | L-796778 acetate is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 acetate is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM. L-796778 acetate has anticonvulsant effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922280-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-123335A. | |
| L-798106 | L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CM9; GW671021. CAS No. 244101-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15274. | |
| L-803087 | L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. L-803087 is >280-fold higher than other somatostatin receptors. L-803087 facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 217480-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108497. | |
| L-817818 | L-817818 is a potent and subtype-selective agonist of the somatostatin receptor. L-817818 provides a direct approach to defining somatostatin receptor physiological functions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 217480-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108498. | |
| L82 | L82 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329227-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15587. | |
| L-826266 | L-826266 is a selective and competitive EP3 receptor antagonist. L-826266 can be used for convulsive disorders research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 244101-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19361. | |
| L82-G17 | L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92285-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148161. | |
| L-838417 | L-838417 is a selective partial agonist at the α2, α3 and α5 subtypes of the GABAA receptor and an antagonist at the α1, with binding Ki values of 0.79 nM, 0.67 nM, 1.67 nM, 267 nM, 2.25 nM and 2183 nM for α1β3γ2, α2β3γ2, α3β3γ2, α4β3γ2, α5β3γ2 and α6β3γ2. L-838417 has anti-anxiety activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 286456-42-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009009. | |
| L-902688 | L-902688 is a potent, selective and orally active EP4 receptor agonist with a Ki of 0.38 nM and an EC50 of 0.6 nM. L-902688 shows >4,000-fold selective for EP4 over other EP and prostanoid receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 634193-54-7. Pack Sizes: 500 μg (11.92 mM * 100 μL in Methanol); 1 mg (11.92 mM * 200 μL in Methanol); 5 mg (11.92 mM * 1 mL in Methanol); 10 mg (11.92 mM * 2 mL in Methanol). Product ID: HY-119163. | |
| Labetalol | Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AH5158; Sch-15719W free base. CAS No. 36894-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121383. | |
| Labetalol (Standard) | Labetalol (Standard) is the analytical standard of Labetalol. This product is intended for research and analytical applications. Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AH5158 (Standard); Sch-15719W free base (Standard). CAS No. 36894-69-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121383R. | |
| Labetuzumab | Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hMN14. CAS No. 219649-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99160. | |
| Labetuzumab govitecan | Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU 130; hMN-14-SN-38. CAS No. 1469876-18-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99681. | |
| L-(+)-Abrine | L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin. Uses: Scientific research. Category: Natural products. Alternative Names: L-Abrine; L-N-Methyltryptophan; N-α-Methyl-L-tryptophan. CAS No. 526-31-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N1436. | |
| Labuxtinib | Labuxtinib (EVT-8565072; THB335) is a potent dual inhibitor of c-Kit and PDGFR. Labuxtinib exhibits potent inhibitory activity against wild-type c-Kit (IC50 = 0.005 μM). Labuxtinib inhibits SCF-dependent and PDGF-dependent cell proliferation, and blocks the proliferation of cells dependent on c-Kit or PDGFR signaling pathways. In animal models of skin allergy, Labuxtinib depletes skin mast cells and significantly alleviates anaphylactic shock responses. Labuxtinib can be used in research on mast cell-related diseases, respiratory diseases, inflammatory diseases, fibrotic diseases, metabolic diseases, and other related conditions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EVT-8565072; THB335. CAS No. 1426449-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156619. | |
| LA-CB1 | LA-CB1 is an Abemaciclib (HY-16297A) derivative that targets CDK4/6 and promotes its degradation via the ubiquitin-proteasome pathway, thereby disrupting the CDK4/6-Cyclin D1-Rb-E2F axis and inducing G0/G1 cell cycle arrest and apoptosis. LA-CB1 exhibits antiproliferative activity against MDA-MB-231 cells, with an IC50 of 0.27 μM, and effectively inhibits epithelial-mesenchymal transition (EMT), cell migration, invasion, and angiogenesis. In highly aggressive models such as triple-negative breast cancer (TNBC), LA-CB1 significantly suppresses tumor growth in a dose-dependent manner. LA-CB1 holds potential for research in the field of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032908-44-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168996. | |
| Laccase, Microorganisms | Laccase, Microorganisms (Denilite IIS) is a multi-copper oxidase (MCOs), which widely exists in microorganisms, plants and fungi, and can catalyze the oxidation of one electron of various phenolic compounds. Laccase can promote the oxidative coupling of single lignin, which plays an important role in the formation and biodegradation of lignin, and also has the potential to cross-link food polymers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Denilite IIS. CAS No. 80498-15-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-P2890. | |
| LacK free acid | LacK (free acid) is a lysine derivative used in lactate acylation studies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1227379-69-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W883690. | |
| Lacnotuzumab | Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCS110. CAS No. 1831128-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99368. | |
| Lactacystin | Lactacystin is a potent, orally active, irreversible, cell-permeable, selective 20S proteasome inhibitor (IC50 = 4.8 μM). Lactacystin also inhibits the lysosomal enzyme cathepsin A. Lactacystin inhibits cell growth and induces apoptosisand cell cycle arrest, and has antiviral and antioxidative activity. Lactacystin induces neurite outgrowth and hypertension. Lactacystin has the potential for the research of cancer, Neurological Disease, hypertension and Malaria, and so on[1][2] [3][4][5][6] [7][8][9][10]. Uses: Scientific research. Category: Induced disease models products. CAS No. 133343-34-7. Pack Sizes: 50 μg; 100 μg; 500 μg. Product ID: HY-16594. | |
| Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine | Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 198284-23-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3976. | |
| Lactate Dehydrogenase (LDH), Porcine Heart | Lactate Dehydrogenase (LDH), Porcine Heart, is an isoenzyme of lactate dehydrogenase derived from porcine heart. Lactate Dehydrogenase (LDH), Porcine Heart, is primarily used in life science research, tissue damage diagnosis, and as an enzyme marker[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LDH, Lactic Dehydrogenase. CAS No. 9001-60-9. Pack Sizes: 1 KU; 5 KU; 10 KU. Product ID: HY-P2807A. | |
| Lactate oxidase, Microorganism | Lactate oxidase (EC 1.13.12.4) belongs to a group of FMN-dependent enzymes and they catalyze a conversion of lactate to pyruvate with a release of hydrogen peroxide. Lactate oxidase can be used in the detection of Lactate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9028-72-2. Pack Sizes: 100 U; 500 U. Product ID: HY-134757. | |
| Lactic acid | Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid also has antimicrobial activity, which can be used as a food preservative[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Lactic acid; E-270. CAS No. 50-21-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2227. | |
| Lactic acid-d3 sodium (60% w/w in water) | Lactic acid-d3 (DL-Lactic acid-d3) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B). Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Lactic acid-d3 sodium; E-270-d3 sodium. CAS No. 1219802-24-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B2227BS1. | |
| Lactic acid-d4 sodium (60% w/w in water) | Lactic acid-d4 (DL-Lactic acid-d4) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B). Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Lactic acid-d4 sodium; E-270-d4 sodium. CAS No. 344299-52-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B2227BS. | |
| Lactic acid sodium (60% w/w in water) | Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative[3].This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M). Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Lactic acid sodium; E-270 sodium. CAS No. 72-17-3. Pack Sizes: 200 μL; 1 mL; 2 mL; 5 mL; 10 mL. Product ID: HY-B2227B. | |
| Lactimidomycin | Lactimidomycin is a glutarimide-containing compound isolated from Streptomyces. Lactimidomycin is a potent inhibitor of eukaryotic translation elongation. Lactimidomycin has a potent antiproliferative effect on tumor cell lines and selectively inhibit protein translation. Lactimidomycin inhibits protein synthesis with an IC50 value of 37.82 nM. Lactimidomycin is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Anticancer and antiviral activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 134869-15-1. Pack Sizes: 200 μg. Product ID: HY-18979. | |
| Lactisole | Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole inhibits insulin secretion induced by glucose in mouse islets[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 150436-68-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g. Product ID: HY-W030796A. | |
| Lactitol | Lactitol (D-Lactitol) is a non-absorbable disaccharide and Bacterial regulator. Lactitol reduces the populations of Bacteroides, Clostridium, coliforms and Eubacterium, while increasing the populations of Lactobacillus and Streptococcus. Lactitol can be used in the research of portosystemic encephalopathy and chronic constipation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Lactitol. CAS No. 585-86-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N7104. | |
| Lactofen | Lactofen is a herbicide that targets dicotyledonous weeds and causes oxidative stress, activating the expression of chalcone synthase and chalcone reductase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77501-63-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W019880. | |
| Lactoferrin (17-41) | Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lactoferricin B; Lfcin B. CAS No. 146897-68-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1791. | |
| Lactoferrin from Bovine milk | Lactoferrin from Bovine milk is a substance released by neutrophils. Lactoferrin from Bovine milk is an orally active multifunctional iron binding glycoprotein. Lactoferrin from Bovine milk prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin from Bovine milk also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin from Bovine milk has anti-inflammatory, immunomodulatory, and anti-cancer activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 936541-36-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3161. | |
| Lacto-N-fucopentaose I | Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LNFP I. CAS No. 7578-25-8. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-W019806. | |
| Lactonic sophorolipid | Lactonic sophorolipid is an apoptosis inducer and antimicrobial surfactant with antitumor activity. Lactonic sophorolipid regulates Bax/Bcl-gene expression through caspase-3/9 and induces apoptosis in tumor cells. Lactonic sophorolipid can disrupt cell membrane permeability and exert antibacterial effects (MIC for oral pathogens is 100-400 μg/mL). Lactonic sophorolipid promotes mitochondrial membrane potential depolarization, activates the intrinsic apoptotic pathway, and can synergize with antibiotics to enhance the antibacterial effect. Lactonic sophorolipid can be used in liver cancer research and the development of oral hygiene antibacterial agents[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 148409-20-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137371. | |
| Lacto-N-neotetraose | Lacto-N-neotetraose (LNnT) is an endogenous metabolite. Lacto-N-neotetraose can inhibit TNF-α induced IL-8 secretion in immature epithelial cells. Lacto-N-neotetraose has anti-inflammatory avtivity, and can improve the wound closure[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LNnT. CAS No. 13007-32-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N9445. | |
| Lacto-N-tetraose | Lacto-N-tetraose is the significant core structure of human milk oligosaccharides (HMOs) naturally existing in human milk. Lacto-N-tetraose is consist of galactose, N-acetylglucosamine, and glucose moieties. Lacto-N-tetraose has prebiotic effect, immune regulatory effect, anti-inflammatory effects, intestinal cell responses regulatory effect, antibacterial activity and antiviral activity. Lacto-N-tetraose has been widely added to infant formula[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14116-68-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-N9448. | |
| Lacto-N-triose II | Lacto-N-triose II is a core structural unit of human milk oligosaccharides (HMOs). Lacto-N-triose II owns nutraceutical potentials and can be used in the production of complex HMOs[1]. Uses: Scientific research. Category: Natural products. CAS No. 75645-27-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-N10514. | |
| Lactose | Lactose is a β-galactoside consisting of galactose and glucose residues, the main carbohydrate in mammalian breast milk. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory functions[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B2123. | |
| Lactosylceramide (bovine buttermilk) | Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a sphingolipid that highly expressed on the plasma membranes of human phagocytes. Lactosylceramide mediates phagocytosis, chemotaxis, and superoxide generation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LacCer (bovine buttermilk). CAS No. 4682-48-8. Pack Sizes: 1 mg. Product ID: HY-154921. | |
| Lactupicrin | Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC50 of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lactucopicrin. CAS No. 65725-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8290. | |
| Lactyl-CoA | Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1926-57-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-141540. | |
| Ladarixin | Ladarixin (DF 2156A free base) is an orally active, allosteric non-competitive and dual CXCR1 and CXCR2 antagonist. Ladarixin can be used for the research of COPD and asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DF 2156A free base. CAS No. 849776-05-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-19519. | |
| Ladarixin sodium | Ladarixin sodium (DF 2156A) is an orally active, allosteric non-competitive and dual CXCR1 and CXCR2 antagonist. Ladarixin sodium can be used for the research of COPD and asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DF 2156A. CAS No. 865625-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19519A. | |
| Ladiratuzumab | Ladiratuzumab (hLIV22) is a humanized monoclonal antibody against zinc transporter LIV-1/ZIP6. Ladiratuzumab is conjugated to MMAE (HY-15162) via a cleavable dipeptide linker to synthesize an antibody-drug conjugate (ADC) Ladiratuzumab vedotin (HY-P99683). Ladiratuzumab vedotin selectively targets LIV-1 protein overexpressed on the surface of tumor cells, enters cells through antibody-mediated receptor endocytosis, releases MMAE to inhibit microtubule polymerization, and kills adjacent tumor cells with a bystander effect. Ladiratuzumab can be used in the study of solid tumors such as metastatic triple-negative breast cancer (mTNBC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hLIV22. CAS No. 1629760-28-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99682. | |
| Ladiratuzumab vedotin | Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC50: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SGN-LIV1A. CAS No. 1629760-29-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99683. | |
| Laduviglusib | Laduviglusib (CHIR-99021) is a potent, selective and orally active GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib enhances mouse and human embryonic stem cells self-renewal. Laduviglusib induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-99021; CT99021. CAS No. 252917-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10182. | |
| Laduviglusib (GMP) | Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-99021 (GMP); CT99021 (GMP). CAS No. 252917-06-9. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-10182G. | |
| Laduviglusib monohydrochloride | Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-99021 monohydrochloride; CT99021 monohydrochloride. CAS No. 1797989-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10182A. | |
| Laduviglusib (Standard) | Laduviglusib (Standard) is the analytical standard of Laduviglusib. Laduviglusib (CHIR-99021) is a potent, selective and orally active GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib enhances mouse and human embryonic stem cells self-renewal. Laduviglusib induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-99021 (Standard); CT99021 (Standard). CAS No. 252917-06-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10182R. | |
| Laduviglusib trihydrochloride | Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-99021 trihydrochloride; CT99021 trihydrochloride. CAS No. 1782235-14-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10182B. | |
| Laflunimus | Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HR325. CAS No. 147076-36-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101813. | |
| LAH4 | LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 184776-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0311. | |
| LAH4-L1 | LAH4-L1 Is a histidine-rich cell penetrating peptide. LAH4-L1 can form complexes with DNA or siRNA and help their transport[1]. Uses: Scientific research. Category: Peptides. CAS No. 882690-68-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10733. | |
| LAH5 | LAH5 is an amphipathic cell-penetrating peptide. LAH5 forms nanocomplexes with both RNP and RNP/HDR cargo[1]. Uses: Scientific research. Category: Peptides. CAS No. 476169-12-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10068. | |
| L-Alanine | L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-2-Aminopropionic acid. CAS No. 56-41-7. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 5 g. Product ID: HY-N0229. | |
| L-Alanine-13C2 | L-Alanine-13C2 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-2-Aminopropionic acid-13C2. CAS No. 65163-26-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0229S9. | |
| L-Alanine-13C3 | L-Alanine-13C3 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-2-Aminopropionic acid-13C3. CAS No. 100108-77-8. Pack Sizes: 5 mg. Product ID: HY-N0229S8. | |
| L-Alanine-13C3,15N | L-Alanine-13C3,15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-2-Aminopropionic acid-13C3,15N. CAS No. 202407-38-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0229S10. | |
| L-Alanine-15N | L-Alanine-15N is the 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-2-Aminopropionic acid-15N. CAS No. 25713-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0229S2. | |
| L-Alanosine | L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine is the inhibitor for methylthioadenosine phosphorylase (MTAP)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC-153353; SDX-102. CAS No. 5854-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16933. | |
| Lalistat 1 | Lalistat 1 is a potent, selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM. Lalistat 1 is a inhibitor of immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or β-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501104-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116815. | |
| Lalistat 2 | Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234569-09-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128144. | |
| L-α-Lecithin (egg yolk), 75% | L-α-Lecithin (egg yolk), 75% is a kind of biological materials. L-α-Lecithin (egg yolk), 75% can be used for studying cell membrane structure, biofilm potential, liposome research, etc[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-α-Phosphatidylcholine (egg yolk), 75%; 1,2-Diacyl-sn-glycero-3-phosphocholine (egg yolk), 75%; egg yolk Lecithins, 75%. CAS No. 8002-43-5. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-B2235A. | |
| L-α-Lecithin (egg yolk, Type XVI-E), 99% | L-α-Lecithin (egg yolk, Type XVI-E), 99% (L-α-Phosphatidylcholine (egg yolk, Type XVI-E), 99%) is an active biomaterial. L-α-Lecithin (egg yolk, Type XVI-E), 99% forms liposomes with compounds (PF or BA). L-α-Lecithin (egg yolk, Type XVI-E), 99% increases membrane fluidity and affects microemulsion stability and fluorescence intensity stained with Nile red (HY-D0718). L-α-Lecithin (egg yolk, Type XVI-E), 99% It can be used for cell membrane structure research, biological membrane potential research, and liposome research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-α-Phosphatidylcholine (egg yolk, Type XVI-E), 99%, lyophilized powder; 1,2-Diacyl-sn-glycero-3-phosphocholine (egg yolk, Type XVI-E), 99%; egg yolk Lecithins, Type XVI-E, 99%. CAS No. 8002-43-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2235B. | |
| L-α-Lecithin (soybean) | L-α-Lecithin (soybean) is an orally active phospholipid. L-α-Lecithin (soybean) increases the bioavailability of Lutein in plasma and eyes of Rattus norvegicus, enhances plasma Glutathione peroxidase activity, and regulates fatty acids in plasma and tissues[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8002-43-5. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B2235C. | |
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