MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| L-Hydroxyproline-d3 | L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. Uses: Scientific research. Category: Signaling pathways. CAS No. 1356016-86-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-40135S. |  |
| L-Hyoscyamine | L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hyoscyamine. CAS No. 101-31-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0471. | |
| LI-2242 | LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor. LI-2242 has inhibition effect for IP6K1, IP6K2, IP6K3 and IPMK with IC50 values of 31 nM, 42 nM, 8.7 nM and 1944 nM, respectively. LI-2242 can be used for thew research of type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762762-17-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153530. | |
| Liafensine | Liafensine (BMS-820836) is an orally active, blood-brain barrier-permeable monoamine reuptake inhibitor, with an IC50 of 5.67 nM against DAT, 1.08 nM against SERT, and 7.99 nM against NET. Liafensine binds to DAT to block dopamine reuptake. Liafensine binds to SERT to block serotonin reuptake. Liafensine binds to NET to block norepinephrine reuptake. Liafensine can be used in studies related to depression[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-820836. CAS No. 1198790-53-2. Pack Sizes: 1 mg. Product ID: HY-19907. | |
| Liarozole | Liarozole (R75251; R85246) is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC50=7 μM), resulting in increased tissue levels of retinoic acid. Liarozole shows antitumoral properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R75251. CAS No. 115575-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106019. | |
| Liarozole dihydrochloride | Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA (IC50=7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R75251 dihydrochloride. CAS No. 1883548-96-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106019C. | |
| Libivirumab | Libivirumab (17.1.41) is a human anti-HBV monoclonal antibody. Libivirumab shows neutralization activity with IC50s of 35, 130 ng/mL for HBsAg, HBeAg, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17.1.41. CAS No. 569658-79-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99703. | |
| LIBX-A401 | LIBX-A401 is a selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor with a human IC50 values of 0.38 μM and a Kd of 0.72 μM. LIBX-A401 binds to ACSL4 in an ATP-dependent manner, stabilizes the C-terminal domain, alters the fatty acid gate region, and interacts with residues A329 and Q302 within the fatty acid binding site. LIBX-A401 exhibits anti-ferroptosis properties in cells. LIBX-A401 can be used for the researches of cancer and parkinson's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3111845-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173432. | |
| Licaminlimab | Licaminlimab (OCS-02) is a single-chain anti-TNF alpha antibody fragment. TNF alpha is an inflammatory cytokine produced by macrophages and monocytes during inflammation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OCS-02. CAS No. 1688648-13-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99704. | |
| Licarbazepine | Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIA 2-005; GP 47779. CAS No. 29331-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108506. | |
| Licochalcone A | Licochalcone A (LCA), a flavonoid isolated, presents obvious anti-cancer effects, displays broad-spectrum inhibition against UDP-glucuronosyltransferases (UGTs)[1]. Licochalcone A (LCA) exhibits strong inhibitory effects against UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A9, and 2B7 (both IC50 and Ki values lower than 5 μM) [2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58749-22-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0372. | |
| Licochalcone B | Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7?NLRP3 interaction[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58749-23-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0373. | |
| Licochalcone C | Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 144506-14-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0374. | |
| Licochalcone D | Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza uralensis, is a potent and orally active inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 144506-15-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N4187. | |
| Licochalcone E | Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864232-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4182. | |
| Licofelone | Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML-3000. CAS No. 156897-06-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1452. | |
| Licoricesaponin G2 | Licoricesaponin G2 is an orally active component found in Licorice. Licoricesaponin G2 significantly ameliorates Bleomycin (HY-108345)-induced pulmonary fibrosis by inhibiting the TNF-α signaling pathway, reducing epithelial-mesenchymal transition, and decreasing extracellular matrix deposition. Licoricesaponin G2 inhibits cancer cells proliferation, migration, inhibits PI3K/AKT/mTOR signaling pathway and increases ROS production. Licoricesaponin G2 can be used for the research of lung cancer and pulmonary fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118441-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6983. | |
| Licorice-saponin H2 | Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance[1]. Uses: Scientific research. Category: Natural products. Alternative Names: (18β,20α)-Glycyrrhizic acid. CAS No. 118441-85-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6911. | |
| Lidocaine | Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lignocaine. CAS No. 137-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g. Product ID: HY-B0185. | |
| Lidocaine-d10 | Lidocaine-d10 is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851528-09-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0185S1. | |
| Lidocaine hydrochloride | Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lignocaine hydrochloride. CAS No. 73-78-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g. Product ID: HY-B0185A. | |
| Lidocaine impurity 12 | Lidocaine impurity 12 is an impurity of Lidocaine (HY-B0185). Uses: Scientific research. Category: Signaling pathways. CAS No. 857170-72-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z6535. | |
| Lidoflazine | Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3416-26-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-112075. | |
| Liensinine | Liensinine is a bisbenzylisoquinoline alkaloid. By inhibiting the PI3K/AKT and JNK/p38-MAPK signaling pathways, Liensinine suppresses autophagy and apoptosis, clears Aβ, and exerts anti-inflammatory, antioxidant and neuroprotective effects. Liensinine activates AMPK and inhibits the expression of HIF-1α and VEGF, thereby suppressing angiogenesis. Liensinine exerts anti-tumor effects through ROS-mediated inhibition of the JAK2/STAT3 signaling pathway. Liensinine can be used for the research of diseases such as Alzheimer's disease, hepatocellular carcinoma, osteosarcoma, sepsis-induced organ injury and stroke[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2586-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0484. | |
| Lifastuzumab | Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody. Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) (HY-15162) through ADC Linker to form an antibody-drug conjugate (ADC) Lifastuzumab vedotin (HY-P99705) with anticancer activity. Lifastuzumab vedotin can be studied in research for non-small cell lung cancer and ovarian cancer. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1615697-16-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99970. | |
| Lificiguat | Lificiguat binds to the β subunit of soluble guanylyl cyclase(sGC) with Kd of 0.6-1.1 μM in the presence of CO. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YC-1. CAS No. 170632-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14927. | |
| Lifirafenib | Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-283. CAS No. 1446090-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18957. | |
| Lifitegrast | Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR 1118; SHP-606. CAS No. 1025967-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-19344. | |
| Lifitegrast sodium | Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR 1118 sodium; SHP-606 sodium. CAS No. 1119276-80-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19344A. | |
| Ligandrol | Ligandrol is an orally active, selective androgen receptor (AR) agonist. Ligandrol enhances protein synthesis, inhibits muscle breakdown and oxidative stress, improves muscle cell viability and bone tissue microstructure, and reduces Cisplatin (HY-17394)-induced muscle toxicity and apoptosis. Ligandrol promotes muscle growth, protects bone structure, and has anti-diabetic, anti-apoptotic and antioxidant effects. Ligandrol can antagonize Streptozotocin (HY-13753) damage to pancreatic islets and improve the symptoms of type 2 diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LGD-4033. CAS No. 1165910-22-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13981. | |
| Ligelizumab | Ligelizumab (QGE 031) is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor FcεRI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-α production and regulatory T cell (Treg) induction function of plasmacytoid dendritic cells (pDC). Ligelizumab can be used in the study of allergic diseases (such as chronic spontaneous urticaria, allergic asthma)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: QGE 031; Anti-IGHE Recombinant Antibody. CAS No. 1322627-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99300. | |
| Lignin | Lignin (Lignine) is a natural complex biopolymer with biodegradable and biocompatible. Lignin is the main component of plant cell walls and is a renewable aromatic polymer. Lignin has strongly antioxidant activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lignine. CAS No. 9005-53-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-111830. | |
| Lignin alkali | Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8068-5-1. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-W250112. | |
| Ligninase | Ligninase is a general term for extracellular heme-containing peroxidases produced by Phanerochaete chrysosporium. Ligninase can catalyze lignin degradation. Ligninase can be used in waste treatment and detoxification of environmental pollutants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 42613-30-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-E70387. | |
| Lignoceric acid | Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro?hepato?renal syndrome and adrenoleukodystrophy research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tetracosanoic acid. CAS No. 557-59-5. Pack Sizes: 10 mM * 1 mL in THF; 50 mg; 100 mg. Product ID: HY-121883. | |
| Lignoceric acid-d4-1 | Lignoceric acid-d4-11 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro?hepato?renal syndrome and adrenoleukodystrophy research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219794-59-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-121883S3. | |
| Ligufalimab | Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody. Ligufalimab does not induce RBC hemagglutination, and induces phagocytosis. Ligufalimab shows anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK 117. CAS No. 2428381-55-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99706. | |
| Ligustilide | Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4431-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0401. | |
| Ligustroflavone | Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nuezhenoside. CAS No. 260413-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0546. | |
| Ligustroside | Ligustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ligstroside. CAS No. 35897-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N3383. | |
| Ligustrosidic acid | Ligustrosidic acid is a natural compound isolated from ligustrum japonicum and ligustrum lucidum[1]. Uses: Scientific research. Category: Natural products. CAS No. 96382-89-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6874. | |
| Lilotomab | Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HH1. CAS No. 1453362-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99707. | |
| Limantrafin | Limantrafin (CB-103) is a first-in-class, orally active protein-protein interaction (PPI) inhibitor of the NOTCH transcriptional activation complex. Limantrafin has anti-tumor activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CB-103. CAS No. 218457-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135145. | |
| limertinib | limertinib (ASK120067) is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). limertinib is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASK120067. CAS No. 1934259-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138751. | |
| Limonin | Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Limonoic acid 3,19:16,17 dilactone. CAS No. 1180-71-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-17411. | |
| Limonin (Standard) | Limonin (Standard) is the analytical standard of Limonin. This product is intended for research and analytical applications. Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Limonoic acid 3,19:16,17 dilactone (Standard). CAS No. 1180-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17411R. | |
| Linaclotide | Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Uses: Scientific research. Category: Signaling pathways. CAS No. 851199-59-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17584. | |
| Linaclotide acetate | Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Uses: Scientific research. Category: Signaling pathways. CAS No. 851199-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17584A. | |
| Linafexor | Linafexor (CS-0159) is a FXR agonist and bile acid homeostasis modulator. Linafexor exerts its effects by activating FXR, a regulator of liver function. Linafexor is applicable to research related to primary sclerosing cholangitis (PSC). Linafexor is also suitable for research in the field of metabolic dysfunction-associated steatohepatitis (MASH)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CS-0159. CAS No. 2765593-43-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160929. | |
| Linagliptin | Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 1356. CAS No. 668270-12-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-10284. | |
| Linalool-d3 | Linalool-d3 is the deuterium labeled Linalool[1]. Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity[2].Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1216673-02-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0368S. | |
| Linalool (Standard) | Linalool (Standard) is the analytical standard of Linalool. This product is intended for research and analytical applications. Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity[1].Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78-70-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0368R. | |
| Linalyl acetate | Linalyl acetate is the principal components of many plant essential oils. Linalyl acetate exhibits anti-anxiety, anti-inflammatory, anti-diabetic, anti-stress, and cardiovascular-regulatory effects. Linalyl acetate is orally active[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 115-95-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-N6948. | |
| Linarin | Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Buddleoside; Linarine. CAS No. 480-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N0528. | |
| Linavonkibart | Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: SRK-181. CAS No. 2640981-30-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990069. | |
| Linclatamig | Linclatamig (BLYG8824A) is a humanized IgG1 T-cell engaging bispecific antibody (TCB) targeting LY6G6D and CD3. Linclatamig can bind to LY6G6D and CD3-positive T cells, forming an immunological synapse to promote T cell-mediated killing of LY6G6D-positive cells. Linclatamig can be used in colorectal cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BLYG8824A; RG6286. CAS No. 2885203-43-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990925. | |
| Lincomycin | Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: U-10149. CAS No. 154-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117660. | |
| Lincomycin hydrochloride | Lincomycin hydrochloride (U10149A) is an orally active lincosamide antibiotic. Lincomycin hydrochloride binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: U10149A. CAS No. 859-18-7. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-B0417A. | |
| Linderalactone | Linderalactone is an important sesquiterpene lactone isolated from Lindera aggregata. Linderalactone inhibits cancer growth by modulating the expression of apoptosis-related proteins and inhibition of JAK/STAT signalling pathway. Linderalactone also inhibits the proliferation of the lung cancer A-549 cells with an IC50 of 15 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 728-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0781. | |
| Linderane | Linderane, isolated from the root of Lindera aggregata, is an irreversible inhibitor cytochrome P450 2C9 (CYP2C9). Linderane has the potential to relieve pain and cramp[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13476-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0688. | |
| Lindleyin | Lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors. Lindleyin binds to ERα with estrogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59282-56-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2448. | |
| Linerixibat | Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT. Linerixibat can be used as lipid-lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK2330672. CAS No. 1345982-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16643. | |
| Linezolid | Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU-100766. CAS No. 165800-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394. | |
| Linezolid-d3 | Linezolid-d3 (PNU-100766-d3) is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU-100766-d3. CAS No. 1127120-38-0. Pack Sizes: 1 mg. Product ID: HY-10394S. | |
| Linezolid (Standard) | Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU-100766 (Standard). CAS No. 165800-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394R. | |
| Linifanib | Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-869; AL-39324. CAS No. 796967-16-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50751. | |
| Link N peptide | Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 197295-74-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P10954. | |
| Linoleamide | Linoleamide is a linoleic acid amide. Linoleamide regulates Ca (II) ux and inhibits the erg current[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Linoleic acid amide. CAS No. 3999-1-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N7848. | |
| Linoleic acid | Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60-33-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0729. | |
| Linoleic acid-13C18 | Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287111-25-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N0729S2. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.