MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Asundexian | Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY-2433334. CAS No. 2064121-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137431. |  |
| Asunercept | Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein (hIgG1) targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APG101; CAN008. CAS No. 1450882-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99445. | |
| Asvasiran sodium | Asvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALN-RSV01 sodium. CAS No. 1386946-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158824A. | |
| ASX-173 | ASX-173 is an orally active inhibitor of asparagine synthetase (ASNS) (IC50 = 0.113 μM, Ki = 0.4 nM). ASX-173 enhances the anticancer activity of L-asparaginase (ASNase) (HY-P1923). ASX-173 disrupts nucleotide synthesis and induces leukemia cell cycle arrest, apoptosis and autophagy in leukemia cells in combination with ASNase. ASX-173 slows the growth of OCI-AML2 xenografts in combination with ASNase. ASX-173 is indicated for the study of acute lymphoblastic leukemia, acute myeloid leukemia, colorectal cancer, and other cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748800-08-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175282. | |
| Asymmetric dimethylarginine | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine. CAS No. 30315-93-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113216. | |
| Asymmetric-dimethylarginine-d6 dihydrochloride | Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine-d6 dihydrochloride. CAS No. 1313730-20-9. Pack Sizes: 1 mg. Product ID: HY-113216BS. | |
| Asymmetric dimethylarginine (Standard) | Hesperetin (Standard) is the analytical standard of Hesperetin. This product is intended for research and analytical applications. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine (Standard). CAS No. 30315-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113216R. | |
| AT 1001 | AT 1001 is an orally effective α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) antagonist with a Ki value of 2.64 nM. AT 1001 reversibly blocks Epibatidine (HY-101078)-induced inward currents in HEK cells transfected with α3β4 nAChR. AT 1001 dose-dependently blocks nicotine self-administration behavior in rats, alleviates gluten-induced gastrointestinal symptoms, blocks tight junction toxin-induced immune responses, and reduces the incidence of type 1 diabetes in rats. AT 1001 can be used in the research of nicotine addiction and celiac disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314801-63-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135783. | |
| AT-130 | AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 211364-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100028. | |
| AT-56 | AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 162640-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13988. | |
| AT6 | AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4). Uses: Scientific research. Category: Signaling pathways. CAS No. 2098836-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112375. | |
| AT7519 | AT7519 (AT7519M) as a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT7519M. CAS No. 844442-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 857531-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12059. | |
| AT791 | AT791 is a potent and orally bioavailable TLR7 and TLR9 inhibitor. AT791 inhibits TLR7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219962-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124603. | |
| AT9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 896466-04-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-50514. | |
| Atabecestat | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer's Disease treatment[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-54861911. CAS No. 1200493-78-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-109052. | |
| Ataluren | Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PTC124. CAS No. 775304-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14832. | |
| Ataluren (Standard) | Ataluren (Standard) is the analytical standard of Ataluren. This product is intended for research and analytical applications. Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PTC124 (Standard). CAS No. 775304-57-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14832R. | |
| Atazanavir | Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-232632. CAS No. 198904-31-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367. | |
| Atazanavir sulfate | Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor with blood-brain barrier permeability. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-232632 sulfate. CAS No. 229975-97-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367A. | |
| ATB107 | ATB107 is a potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 455325-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76212. | |
| Atebimetinib | Atebimetinib (IMM-1-104) is a novel orally dual-MEK inhibitor with anti-pancreatic cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMM-1-104. CAS No. 2669009-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172415. | |
| Atenolol | Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-Atenolol. CAS No. 29122-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-17498. | |
| Atenolol-d7 | Atenolol-d7 is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-Atenolol-d7. CAS No. 1202864-50-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-17498S. | |
| Atezolizumab | Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPDL3280A; RG-7446; RO-5541267. CAS No. 1380723-44-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9904. | |
| ATF3-IN-1 | ATF3-IN-1 is a ferroptosis and ATF3 inhibitor. ATF3-IN-1 inhibits oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, exerting anti-ischemic stroke effects. ATF3-IN-1 can attenuate ischemia/reperfusion (I/R) injury and improve neuronal survival. ATF3-IN-1 has neuroprotective effects and can be used to study ischemic stroke[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2952703-90-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175032. | |
| ATF3 inducer 1 | ATF3 inducer 1 is a potent ATF3 inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3038756-30-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151923. | |
| ATF4-IN-1 | ATF4-IN-1 (Compound 21) is an ATF4 inhibitor and also an eIF2B activator. ATF4-IN-1 can be used in research on neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2991057-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-158201. | |
| ATF4-IN-2 | ATF4-IN-2 (Compound 29) is a ATF4 inhibitor with a IC50 value of 47.71 nM. ATF4-IN-2 can be used in the study of neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2991057-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158202. | |
| Atg4B-IN-2 | Atg4B-IN-2 is a potent competitive Atg4B inhibitor with Ki value of 3.1 μM, also possesses declining PLA2 inhibitory potency, IC50s of 11 μM and 3.5 μM for Atg4B and PLA2, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer agents via autophagy inhibition[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2765008-88-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-144636. | |
| ATG7-IN-1 | ATG7-IN-1 (Compound 37) is a potent and selective inhibitor of ATG7 (IC50 = 62 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 2226229-87-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-145371. | |
| ATG7-IN-2 | ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226227-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146130. | |
| ATG7-IN-3 | ATG7-IN-3 (Compound 18) is a potent ATG7 inhibitor with an IC50 of 0.048 μM. ATG7-IN-3 inhibits Autophagy. ATG7-IN-3 inhibits the formation of LC3B puncta. ATG7-IN-3 can be used in the researches of glioma and colon cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226229-76-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-146131. | |
| Atglistatin | Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor which inhibits lipolysis with an IC50 of 0.7 μM in vitro. Uses: Scientific research. Category: Signaling pathways. CAS No. 1469924-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15859. | |
| ATI-2341 | ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1337878-62-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0172. | |
| Atibuclimab | Atibuclimab (IC14), is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab attenuates Lipopolysaccharides (HY-D1056) (LPS)-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. Atibuclimab can be used for the research of amyotrophic lateral sclerosis, sepsis, community-acquired pneumonia, or acute lung injury[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IC14. CAS No. 2417175-94-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99008. | |
| Aticaprant | Aticaprant (CERC-501) is a potent and centrally-penetrant kappa opioid receptor antagonist with a Ki of 0.807 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CERC-501; LY-2456302. CAS No. 1174130-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101718. | |
| ATIC-IN-1 acetate | ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3067165-96-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150252A. | |
| Atigotatug | Atigotatug (BMS-986012) is a fully human IgG1 antibody binds specifically to FucGM1 with an EC50 of 0.15 nmol/L for FucGM1. Atigotatug is a FcγRIIIa ligand with a Kd of 21 nmol/L. Atigotatug demonstrates antitumor efficacy in multiple mouse small cell lung cancer models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986012. CAS No. 2733581-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990902. | |
| Atinumab (NG-101) | Atinumab (NG-101) is a CHO-expressed human antibody that targets RTN4/NOGO. Atinumab (NG-101) carries a huIgG4 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.62 kDa. The isotype control for Atinumab (NG-101) can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: NG-101. CAS No. 1226761-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990551. | |
| Atinvicitinib | Atinvicitinib is an orally active and selective JAK1 inhibitor. Atinvicitinib blocks signaling of JAK1-dependent pruritogenic and pro-inflammatory cytokines, including those in the IL-31, IL-4, and IL-13 pathways. Atinvicitinib can be used for the researches of pruritus associated with allergic dermatitis and canine atopic dermatitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2169273-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145551. | |
| Atipamezole | Atipamezole (MPV 1248) is a potent α2-adrenoceptor antagonist with a Ki of 1.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPV 1248. CAS No. 104054-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12380A. | |
| Atipamezole hydrochloride | Atipamezole (MPV-1248) hydrochloride is a potent α2-adrenoceptor antagonist with a Ki of 1.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPV-1248 hydrochloride. CAS No. 104075-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12380. | |
| ATM-3507 | ATM-3507 is a potent tropomyosin inhibitor with IC50s from 3.83-6.84 μM in human melanoma cell lines. Uses: Scientific research. Category: Signaling pathways. CAS No. 1861449-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100948. | |
| ATM Inhibitor-10 | ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1941214-06-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118911. | |
| ATN-161 | ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. Uses: Scientific research. Category: Signaling pathways. CAS No. 262438-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13535. | |
| ATN-161 trifluoroacetate salt | ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATN-161 TFA salt. CAS No. 904763-27-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13535A. | |
| ATN-224 | ATN-224 is an orally active Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bischolinetetrathiomolybdate. CAS No. 649749-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16074. | |
| Atogepant | Atogepant (MK-8031) is an orally active and selective calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-8031; AGN-241689. CAS No. 1374248-81-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109022. | |
| Atomoxetine hydrochloride | Atomoxetine (Tomoxetine) hydrochloride is a selective noradrenaline reuptake inhibitor with Ki values of 5 nM, 77 nM and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride is a potent Na+ channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tomoxetine hydrochloride; (R)-Tomoxetine hydrochloride; LY 139603. CAS No. 82248-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17385. | |
| Atopaxar | Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E5555; ER-172594-00. CAS No. 751475-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-18200. | |
| Atorvastatin | Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 134523-00-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0589. | |
| Atorvastatin calcium hydrate | Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver. Uses: Scientific research. Category: Signaling pathways. CAS No. 344423-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-112490. | |
| Atorvastatin hemicalcium salt | Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, with blood-brain barrier permeability. Atorvastatin hemicalcium salt has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI-981; Atorvastatin hemicalcium. CAS No. 134523-03-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17379. | |
| Atorvastatin sodium | Atorvastatin sodium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin sodium inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 134523-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108257. | |
| Atosiban | Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RW22164; RWJ22164. CAS No. 90779-69-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17572. | |
| Atosiban acetate | Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RW22164 acetate; RWJ22164 acetate. CAS No. 914453-95-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17572A. | |
| Atovaquone | Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasites mitochondrial cytochrome bc1 complex. Atovaquone is against human and P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Atavaquone. CAS No. 95233-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13832. | |
| ATP | ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-triphosphate. CAS No. 56-65-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2176. | |
| ATP-ArN3 | ATP-ArN3 is a UV-activatable ATP-crosslinker analog. ATP-ArN3 relys on UV irradiation to activate the aryl azide (ArN3) crosslinking group and conjugate substrate to kinases and associated proteins[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1224198-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-171145. | |
| ATP disodium salt | ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-triphosphate disodium salt; Disodium adenosine triphosphate. CAS No. 987-65-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0345A. | |
| ATP disodium salt, 100 mM Solution, PCR Grade | ATP (Adenosine 5'-triphosphate) disodium salt, 100 mM Solution, PCR Grade is a central component of energy storage and metabolism in vivo. ATP disodium salt, 100 mM Solution, PCR Grade provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt, 100 mM Solution, PCR Grade is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt, 100 mM Solution, PCR Grade can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium salt, 100 mM Solution, PCR Grade has anti-bacterial infection effects and can protect mice against bacterial infection in mice[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-triphosphate disodium salt, 100 mM Solution, PCR Grade. CAS No. 987-65-5. Pack Sizes: 1 mL. Product ID: HY-B2176I. | |
| ATP disodium salt hydrate | ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-triphosphate disodium salt hydrate. CAS No. 34369-07-8. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-W010735. | |
| ATP disodium (Standard) | ATP disodium salt (Standard) is the analytical standard of ATP disodium salt (HY-B0345A). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-triphosphate disodium (Standard); Disodium adenosine triphosphate (Standard). CAS No. 987-65-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0345AR. | |
| ATP disodium trihydrate | ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine-5'-triphosphate disodium trihydrate. CAS No. 51963-61-2. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B2176A. | |
| Atpenin A5 | Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM), and is an effective mKATP channel agonist and cardioprotective agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 119509-24-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126653. | |
| ATPγS tetralithium salt | ATPγS (tetralithium salt) is a P2Y11 receptor agonist, an antioxidant and a neuroprotective agent. ATPγS (tetralithium salt) can be used as a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. ATPγS (tetralithium salt) is active in ATP hydrolysis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine-5'-O-3-thiotriphosphate tetralithium salt; Adenosine 5'-[γ-thio]triphosphate tetralithium salt. CAS No. 93839-89-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108666. | |
| ATP-polyamine-biotin | ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800401-93-7. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D0183. | |
| ATP-Red 1 | ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm). Uses: Scientific research. Category: Signaling pathways. CAS No. 1847485-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-U00451. | |
| ATP-Red 1 (solution) | ATP-Red 1 (solution) is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).Solvent and concentration: DMSO: 1 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1847485-97-5. Pack Sizes: 100 μL; 200 μL. Product ID: HY-DY1014. | |
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