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Z-1,3-diaminopropane HCl
Z-1,3-diaminopropane HCl (CAS# 17400-34-9) is a useful research chemical. Alternative Names: Z-NH(CH2)3NH2 HCl. Grades: ≥ 99 % (HPLC). CAS No. 17400-34-9. Molecular formula: C11H17N2O2Cl. Mole weight: 244.72.
Z-1,4-diaminobutane HCl (CAS# 18807-73-3) is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia. Alternative Names: N-1-Z-1,4-diaminobutane HCl; benzyl 4-aminobutylcarbamate Hydrochloride (1:1); N-benzyloxycarbonyl-1,4-diaminobutane Hydrochloride (1:1); N-Cbz-1,4-diaminobutane Hydrochloride (1:1); N-carbobenzoxy 1,4-diaminobutane Hydrochloride (1:1); 4-benzyloxycarbonylamino-1-butylamine Hydrochloride (1:1); Z-putrescine HCl; (4-aminobutyl)carbamic Acid, Benzyl Ester, Monohydrochloride; (4-aminobutyl)-carbamic Acid, Phenylmethyl Ester Monohydrochloride. Grades: ≥95%. CAS No. 18807-73-3. Molecular formula: C12H18N2O2.HCl. Mole weight: 258.75.
Z-(3S)-1,2,3,4-tetrahydroisoquinolene-3-carboxylic acid. Alternative Names: Z-Tic-OH. Grades: ≥ 98% (HPLC). CAS No. 79261-58-8. Molecular formula: C18H17NO4. Mole weight: 311.34.
Z-4-chloro-DL-phenylalanine
Z-4-chloro-DL-phenylalanine. Alternative Names: Z-DL-Phe(4-Cl)-OH; Z-p-chloro-DL-Phe-OH; (RS)-Z-2-amino-3-(4-chlorophenyl)propionic acid. Grades: ≥ 98% (HPLC). CAS No. 55478-54-1. Molecular formula: C17H16NO4Cl. Mole weight: 333.74.
Z-4-fluoro-D-phenylalanine
Z-4-fluoro-D-phenylalanine. Alternative Names: Z-D-Phe(4-F)-OH; Z-π-fluoro-D-Phe-OH; (R)-Z-2-amino-3-(4-fluorophenyl)propionic acid. Grades: ≥ 99% (HPLC). CAS No. 117467-73-9. Molecular formula: C17H16NO4F. Mole weight: 318.24.
Z-4-fluoro-L-phenylalanine
Z-4-fluoro-L-phenylalanine. Alternative Names: Z-p-fluoro-L-Phe-OH; Z-L-Phe(4-F)-OH; (2S)-2-([(Benzyloxy)carbonyl]amino)-3-(4-fluorophenyl)propanoic acid. Grades: ≥ 99% (HPLC). CAS No. 17543-58-7. Molecular formula: C17H16NO4F. Mole weight: 318.24.
Z-4-fluoro-L-phenylalanine chloromethylketone
Z-4-fluoro-L-phenylalanine chloromethylketone. Alternative Names: Z-4-fluoro-L-phenylalanine chloromethylketone; Z-π-fluoro-Phe-CMK. Grades: ≥ 99% (TLC). CAS No. 400771-48-4. Molecular formula: C18H17NO3ClF. Mole weight: 349.75.
Z-4-Oxo-D-Pro-Ome
Z-4-Oxo-D-Pro-Ome. Alternative Names: Z 4 Oxo D Pro Ome. CAS No. 132431-11-9. Molecular formula: C14H15NO5. Mole weight: 277.27.
Z-4-Oxo-Pro-Ome
A building block used in the synthesis of dipeptidyl peptidase IV inhibitors and HIV integrase inhibitors. Alternative Names: (S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate; (S)-L-benzyl-2-methyl 4-oxopyrrolidine-1,2-dicarboxylate. Grades: 95%. CAS No. 16217-15-5. Molecular formula: C14H15NO5. Mole weight: 277.27.
Z-(4-tert-butyloxycarbonyl)-L-phenylalanine
Z-(4-tert-butyloxycarbonyl)-L-phenylalanine. Alternative Names: Z-L-Phe(4-COOtBu)-OH; Z-(4-carboxy-tert-butyl)-L-phenylalanine. Grades: ≥ 99% (Assay). CAS No. 270567-85-6. Molecular formula: C22H25NO6. Mole weight: 399.34.
Z-6-aminohexanoic acid
Z-6-aminohexanoic acid. Alternative Names: Z-ε-Acp-OH; Z-ε-Ahx-OH. Grades: 99%. CAS No. 1947-00-8. Molecular formula: C14H19NO4. Mole weight: 265.3.
Z-AEVD-FMK is a cell-permeant and irreversible caspase-10 inhibitor. It is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Alternative Names: Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone; (5S,8S,11S,14S)-Methyl 14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,1 3-tetraazahexadecan-16-oate; Z-A-E(OMe)-V-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK. Grades: ≥95%. CAS No. 1135688-47-9. Molecular formula: C28H39FN4O10. Mole weight: 610.63.
Z-Ala-Ala-Asn-AMC
Z-Ala-Ala-Asn-AMC is a standard substrate for legumain (EC 3.4.22.34) originally used for plant enzymes, and later found in mammalian form. Legumain may be a physiologic local regulator of human osteoclast (OCL) activity and may negatively regulate OCL. Alternative Names: Z-AAN-AMC; L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Benzyloxycarbonyl-Ala-Ala-Asn-4-methyl-7-coumarylamide; Benzyloxycarbonylalanyl-alanyl-asparaginyl-4-methyl-7-coumarylamide. Grades: 95%. CAS No. 149697-16-5. Molecular formula: C28H31N5O8. Mole weight: 565.57.
Z-Ala-Ala-OH
Z-Ala-Ala-OH is a useful research chemical, an intermediate for the preparation of pseudopeptide macrobicyclic cages used as receptors for N-protected dipeptide guest molecules. Alternative Names: Z-L-alanyl-L-alanine; N-Cbz-L-Alanyl-L-Alanine; L-Alanine, N-[(Phenylmethoxy)Carbonyl]-L-Alanyl-; Benzyloxycarbonylalanyl Alanine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)Propanamido)Propanoic Acid; Z Ala Ala OH. Grades: ≥ 99% (HPLC). CAS No. 16012-70-7. Molecular formula: C14H18N2O5. Mole weight: 294.31.
Z-Ala-Gly-OH
Z-Ala-Gly-OH. Alternative Names: Z-L-alanyl-L-glycine; N-Carbobenzoxy-L-Alanylgylcine; Z Ala Gly OH. Grades: ≥ 96% (HPLC). CAS No. 3235-17-4. Molecular formula: C13H16N2O5. Mole weight: 280.28.
Z-Ala-His-OMe
Z-Ala-His-OMe is a useful research intermediate for the synthesis of other histidine-containing peptides. Alternative Names: (S)-methyl 2-((S)-2-(benzyloxycarbonylamino)propanamido)-3-(1H-imidazol-4-yl)propanoate; Z Ala His OMe. Grades: ≥ 99% (TLC). CAS No. 32303-82-5. Molecular formula: C18H22N4O5. Mole weight: 374.40.
Z-ALA-LEU-OH
Z-ALA-LEU-OH. Alternative Names: n-benzyloxycarbonyl-l-alanyl-l-leucine; (S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)propanamido)-4-methylpentanoic acid. CAS No. 24959-68-0. Molecular formula: C17H24N2O5. Mole weight: 336.38.
Z-Ala-Lys-OH
Z-Ala-Lys-OH. Alternative Names: N-cbz-l-alanyl-l-lysine; (S)-6-amino-2-((S)-2-(benzyloxycarbonylamino)propanamido)hexanoic acid; Z Ala Lys OH. Grades: 99%. CAS No. 76264-07-8. Molecular formula: C17H25N3O5. Mole weight: 351.40.
Z-Ala-Met-OH
Z-Ala-Met-OH. Alternative Names: Z-L-alanyl-L-methionine; N-cbz-l-alanyl-l-methionine; (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}propanoyl)amino]-4-(methylthio)butanoic acid; Z Ala Met OH. Grades: ≥ 98% (TLC). CAS No. 76264-05-6. Molecular formula: C16H22N2O5S. Mole weight: 354.43.
Z-Ala-Phe-OH
Substrate for carboxypeptidase Y. Alternative Names: Z-L-alanyl-L-phenylalanine; N-Carbobenzoxy-L-alanyl-L-phenylalanine; (S)-2-((S)-2-(benzyloxycarbonylamino)propanamido)-3-phenylpropanoic acid; Z Ala Phe OH. Grades: ≥ 98% (HPLC). CAS No. 2768-53-8. Molecular formula: C20H22N2O5. Mole weight: 370.41.
Z-Ala-Pro-Phe-chloromethylketone
Z-Ala-Pro-Phe-chloromethylketone is an inhibitor of the Ca2+- regulated nuclear scaffold proteinase (CRNSP). Alternative Names: Z-APF-CMK; N-benzyloxycarbonyl-Ala-Pro-Phe-chloromethyl ketone. Grades: >98%. CAS No. 217658-18-9. Molecular formula: C26H30ClN3O5. Mole weight: 499.99.
Z-ALA-PRO-PNA
Z-ALA-PRO-PNA. Alternative Names: benzyl (S)-1-((S)-2-(4-nitrophenylcarbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-ylcarbamate. Grades: >99%. CAS No. 66382-56-7. Molecular formula: C22H24N4O6. Mole weight: 440.45.
Z-Allo-Thr-OMe
Z-Allo-Thr-OMe. CAS No. 98777-34-5. Molecular formula: C13H17NO5. Mole weight: 267.3.
Z-α-aminoisobutyric acid
Z-α-aminoisobutyric acid. Alternative Names: Z-Aib-OH; Z-α-methylalanine. Grades: ≥ 99% (HPLC). CAS No. 15030-72-5. Molecular formula: C12H15NO4. Mole weight: 237.30.
Z-Arg-AMC
Z-Arg-AMC. CAS No. 62037-44-9. Molecular formula: C24H27N5O5. Mole weight: 465.51.
Z-ARG-ARG-AMC
Z-ARG-ARG-AMC. Alternative Names: ZRR-NMec; L-Argininamide,N2-[(phenylmethoxy)carbonyl]-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: >98%. CAS No. 88937-61-5. Molecular formula: C30H39N9O6. Mole weight: 621.68.
Z-Arg-Arg-pNA. 2 HCl
Z-Arg-Arg-pNA is a chromogenic substrate for cathepsin B and stem bromelain. Alternative Names: Cathepsin B Ssubstrate I,colorimetric; Z-Arg-Arg-pNA dihydrochloride; benzyl (S)-5-guanidino-1-((S)-5-guanidino-1-(4-nitrophenylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate dihydrochloride. CAS No. 201807-90-1. Molecular formula: C26H38Cl2N10O6. Mole weight: 657.55.
Z-Arg-Leu-Arg-Gly-Gly-AMC
Z-RLRGG-AMC is a fluorescent substrate for the deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolase (UCH) based on the C-terminus of ubiquitin. CAS No. 167698-69-3. Molecular formula: C40H56N12O9. Mole weight: 848.96.
Z-Arg(NO2)-OH
Z-Arg(NO2)-OH. Alternative Names: N-α-Carbobenzyloxy-Ng-nitro-L-arginine. CAS No. 2034-98-5. Molecular formula: C14H19N5O6. Mole weight: 353.3.
Z-Asn-Gly-OH
Z-Asn-Gly-OH. Alternative Names: Cbz-Asn-Gly-OH; N-benzyloxycarbonyl-L-asparagyl-glycine; Glycine, N-[N2-[(phenylmethoxy)carbonyl]-L-asparaginyl]-. Grades: ≥95% by HPLC. CAS No. 56675-97-9. Molecular formula: C14H17N3O6. Mole weight: 323.30.
Z-Asp-CH2-DCB
Z-Asp-CH2-DCB is a broad caspase inhibitor that blocks apoptosis by non-selectively inhibiting caspase activity. At 1-100 μM, it can dose-dependently block the production of IL-1β, TNF-α, IL-6, and IFN-γ by human peripheral blood mononuclear cells as well as inhibit T cell proliferation. Alternative Names: ICE Inhibitor V; Z-Asp-[(2,6-dichlorobenzoyl)oxy]methane; Caspase-1 Inhibitor V; (3S)-5-(2,6-Dichlorobenzoyl)oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid. Grades: ≥98%. CAS No. 153088-73-4. Molecular formula: C20H17Cl2NO7. Mole weight: 454.3.
Z-Asp(OtBu)-bromomethyl ketone
Z-Asp(OtBu)-bromomethyl ketone. Alternative Names: Z-Asp(OtBu)-bromomethylketone; (S)-tert-butyl 3-(benzyloxycarbonylamino)-5-bromo-4-oxopentanoate. Grades: 99%. CAS No. 153088-76-7. Molecular formula: C17H22BrNO5. Mole weight: 400.26.
Z-ASTD-FMK is a cell-permeant and irreversible inhibitor of endothelial monocyte-activated polypeptide II (EMAP II). Alternative Names: EMAP II inhibitor; Z-Ala-Ser-Thr-Asp(OMe)-Fluoromethylketone; Z-ASTD(OMe)-fmk; Cbz-Ala-Ser-Thr-Asp(OMe)-CH2F. Grades: ≥95%. Molecular formula: C24H33FN4O10. Mole weight: 556.54.
Z-ATAD-FMK is a cell-permeant caspase-12 inhibitor. It was shown to suppress annular cell apoptosis in vitro. Alternative Names: Caspase-12 Inhibitor; Z-ATAD-FMK; Z-ATAD-fluoromethylketone. Grades: ≥95%. Molecular formula: C24H33FN4O9. Mole weight: 540.54.
Z-Aze-OH
Z-Aze-OH. Alternative Names: Cbz-Aze-OH; Cbz Aze OH; Z Aze OH. CAS No. 25654-52-8. Molecular formula: C12H13NO4. Mole weight: 235.24.
Z-benzotriazole
Reagent for introducing the Z-protecting group (carbobenzoxy group). Alternative Names: 1-(Benzyloxycarbonyl)benzotriazole. Grades: ≥ 99.0 %. CAS No. 57710-80-2. Molecular formula: C14H11N3O2. Mole weight: 253.26.
Z-β-alanine
Z-β-alanine has been utilized for various synthesis applications including palladium-catalyzed asymmetric allylation of β-diketones, branched linker that can increase the potency of doxorubicin immunoconjugates, and diacridines that intercalate nucleic acids and inhibit DNA synthesis. Alternative Names: Z-β-Ala-OH; 3-Z-aminopropanoic acid; Z-beta-Ala-OH; carbobenzyloxy-beta-alanine; N-Cbz-beta-alanine; Cbz-beta-alanine; N-Benzyloxycarbonyl-beta-alanine; Cbz-beta-Ala-OH; N-Carbobenzoxy-beta-alanine; 3-(benzyloxycarbonylamino)propanoic acid; 3-{[(benzyloxy)carbonyl]amino}propanoic acid; Z beta Ala OH; Cbz beta Ala OH. Grades: ≥ 99% (HPLC). CAS No. 2304-94-1. Molecular formula: C11H13NO4. Mole weight: 223.20.
Z-β-alanine amide
Z-β-alanine amide. Alternative Names: Z-β-Ala-NH2; 3-Z-aminopropionamide; benzyl N-(2-carbamoylethyl)carbamate; Z-BETA-ALA-NH2; Z-beta-alanine amide; benzyl N-(3-amino-3-oxopropyl)carbamate; Benzyloxycarbonyl-beta-alaninamide; Z BETA ALA NH2. Grades: ≥ 99% (HPLC). CAS No. 886-64-6. Molecular formula: C11H14N2O3. Mole weight: 222.24.
Z-β-alanine methyl ester
Z-β-alanine methyl ester. Alternative Names: Z-β-Ala-OMe; 3-Z-Aminopropionic acid methyl ester; Methyl 3-([(benzyloxy)carbonyl]amino)propanoate; Cbz-beta-alanine methyl ester; Z-BETA-ALA-OME; Cbz-beta-alaninemethyl ester; Z BETA ALA OME. Grades: ≥ 99% (HPLC). CAS No. 54755-77-0. Molecular formula: C12H15NO4. Mole weight: 237.25.
Z-β-cyclohexyl-D-alanine
Z-β-cyclohexyl-D-alanine. Alternative Names: Z-D-Cha-OH; Z-3-cyclohexyl-D-alanine. Grades: ≥ 98% (HPLC). CAS No. 154802-74-1. Molecular formula: C7H23NO4. Mole weight: 305.28.
Z-β-cyclohexyl-D-alanine dicyclohexylammonium salt
ZD 2767P. Alternative Names: N-[[4-[Bis(2-iodoethyl)amino]phenoxy]carbonyl]glutamic acid; 4-[N,N-bis(2-iodoethyl)amino]-phenyl-oxycarbonyl-l-glutamic acid; ZD 2767. CAS No. 156079-88-8. Molecular formula: C16H20I2N2O6. Mole weight: 590.15.
Z-D-2-cyclohexylglycine
Z-D-2-cyclohexylglycine. Alternative Names: Z-D-Chg-OH; Z-cyclohexyl-D-Gly-OH; (2R)-([(Benzyloxy)carbonyl]amino)(cyclohexyl)ethanoic acid. Grades: ≥ 98% (HPLC). CAS No. 69901-85-5. Molecular formula: C16H21NO4. Mole weight: 291.35.
Z-D-Ala-Gly-OH
Z-D-Ala-Gly-OH. Alternative Names: (R)-2-(2-(((Benzyloxy)carbonyl)amino)propanamido)acetic acid; Z D Ala Gly OH. Grades: ≥ 95% (HPLC). CAS No. 34286-66-3. Molecular formula: C13H16N2O5. Mole weight: 280.28.