BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 9-Methyldecanoic acid | 9-Methyldecanoic acid (CAS# 1119-63-7 ) is a useful research chemical. Alternative Names: 9-methyl-decanoic acid; 9-Methylcapric acid. CAS No. 1119-63-7. Molecular formula: C11H22O2. Mole weight: 186.29. |  |
| 9-methylidenefluorene | 9-Methylidenefluorene is an analog of 9-Methylfluorene; a compound that has been shown to be mutagenic in Salmonella typhimurium TA98 and TA100 in the presence of 9000 X g supernantant from Aroclor-induced rats. Alternative Names: 9-Methylene-9H-fluorene; 9H-Fluorene, 9-Methylene-; Fluorenylidenemethane; 9-Methylene-fluorene. CAS No. 4425-82-5. Molecular formula: C14H10. Mole weight: 178.23. | |
| 9-Phenanthrenemethanol | 9-Phenanthrenemethanol, a well-known intermediate in organic synthesis, presents itself as a promising compound with its anti-inflammatory and analgesic properties. Its therapeutic potential is particularly notable in the management of pain and inflammatory diseases, such as arthritis, but further investigation in clinical settings is required to fully harness its benefits. Alternative Names: phenanthren-9-ylmethanol; (9-Phenanthryl)methanol; 9-(Hydroxymethyl)phenanthrene; 9-Hydroxymethylphenanthrene; 9-Phenanthrenemethanol. Grades: 95%. CAS No. 4707-72-6. Molecular formula: C15H12O. Mole weight: 208.26. | |
| 9-Piperazine Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Alternative Names: Levofloxacin EP Impurity I; (-)-(S)-10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. Grades: > 95%. CAS No. 178912-62-4. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| 9-Piperazino Ofloxacin | An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Alternative Names: 10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grades: > 95%. CAS No. 197291-75-1. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| Acamprosate Calcium | Acamprosate calcium is a gamma-aminobutyric acid(GABA)agonist and modulator of glutamatergic systems. It has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Uses: Alcohol deterrents. Alternative Names: Calcium 3-acetamidopropane-1-sulfonate; Calcium 3-(acetylamino)propanesulphonate; 3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt; Calcium Acetylhomotaurine; Alcomed; Sobriol; Aotal calcium; Calcium N-acetylhomotaurinate. Grades: >98.0%. CAS No. 77337-73-6. Molecular formula: C10H20CaN2O8S2. Mole weight: 400.48. | |
| Acarviosine-glucose | An impurity of Acarbose, a medication used for the treatment of diabetes mellitus type 2. Alternative Names: Amylostatin XG; Acarviostatin I00. CAS No. 68128-53-0. Molecular formula: C19H33NO13. Mole weight: 483.5. | |
| Acecainide HCl | Acecainide, also known as N-acetylprocainamide and ASL 601, is a class III antiarrhythmic compound. It increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. Acecainide can be given either intravenously or orally, and is eliminated primarily by renal excretion. Alternative Names: 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide monohydrochloride; Acecainide; N-acetylprocainamide, ASL 601; ASL-601; ASL601. CAS No. 34118-92-8. Molecular formula: C15H24ClN3O2. Mole weight: 313.82. | |
| Acelarin | Acelarin is a DNA synthesis inhibitor with EC50 of 0.2 nM. Acelarin is a prodrug based on an aryloxy phosphoramidate derivative of gemcitabine. It is converted into the active metabolites dFdCDP and dFdCTP. dFdCDP can inhibit ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA replication; dFdCTP can be incorporated into DNA, resulting in premature termination of DNA replication and eventually induction of apoptosis. Phase III clinical trials for the treatment of Pancreatic cancer are on-going. Uses: Pancreatic cancer. Alternative Names: NUC-1031; NUC 1031; NUC1031; GTPL7389; GTPL 7389; GTPL-7389; SCHEMBL17171316; Benzyl (2S)-2-[({[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxy}(phenoxy)phosphoryl)amino]propanoate. Grades: 98%. CAS No. 840506-29-8. Molecular formula: C25H27F2N4O8P. Mole weight: 580.48. | |
| Acetamide, N-(3-cyano-7-ethoxy-4-hydroxy-6-quinolinyl)- | Utilized as a key building block in the synthesis of antimalarial medications, N-(3-cyano-7-ethoxy-4-hydroxy-6-quinolinyl) acetamide stands as a pharmaceutical intermediate deserving of scientific scrutiny. Through its intricate molecular structure and functional capabilities, this compound remarkably aids in the creation of potent weapons against the ravages of malaria. Its value elucidates the significance of chemical compounds in advancing modern pharmacology and medicinal therapies. Alternative Names: N-(3-Cyano-7-ethoxy-4-hydroxyquinolin-6-yl)acetamide. Grades: 95%. CAS No. 848133-75-5. Molecular formula: C14H13N3O3. Mole weight: 271.27. | |
| Acetaminophen Dimer | An oxidatively couple dimer of Acetaminaphen, a medication used for the treatment of fever and mild to moderate pain. Alternative Names: N,N'-(6,6'-Dihydroxy[1,1'-biphenyl]-3,3'-diyl)bisacetamide; Paracetamol Dimer Impurity. Grades: > 95%. CAS No. 98966-14-4. Molecular formula: C16H16N2O4. Mole weight: 300.32. | |
| Acetylcephalotaxine | Acetylcephalotaxine is isolated from the barks of Cephalotaxus fortunei. Uses: Antitumor activity. Alternative Names: O-Acetylcephalotaxine; Cephalotaxine acetate. Grades: 95%. CAS No. 24274-60-0. Molecular formula: C20H23NO5. Mole weight: 357.4. | |
| Acetylcorynoline | Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal / anti-inflammatory. Alternative Names: (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate; Corynoline acetate; O-Acetylcorynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-. Grades: >98%. CAS No. 18797-80-3. Molecular formula: C23H23NO6. Mole weight: 409.43. | |
| Acetyl-(D-Arg2)-GRF (1-29) amide (human) acetate | Acetyl-(D-Arg2)-GRF (1-29) amide (human) is a GRF antagonist. Grades: 98%. | |
| Acetyldihydromicromelin A | Acetyldihydromicromelin A comes from the herbs of Micromelum sp. Alternative Names: (1R,2R,4R,5R)-4-(7-Methoxy-2-oxo-2H-chromen-6-yl)-1-methyl-3,6-di oxabicyclo[3.1.0]hex-2-yl acetate. Grades: > 95%. CAS No. 94285-22-0. Molecular formula: C17H16O7. Mole weight: 332.3. | |
| Acetyl-Lys5-octreotide Acetate | Acetyl-Lys5-octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: Lys(Ac)-Octreotide Acetate; D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7). Grades: 98%. Molecular formula: C51H68N10O11S2.xC2H4O2. Mole weight: 1061.28 (free base). | |
| Aconine | Aconine is extracted form the roots of Aconitum kusnezoffii Reichb. Uses: A neurotoxin. Alternative Names: (15S,16S)-20-Ethyl-1α,6α,16-trimethoxy-4-(methoxymethyl)aconitane-3α,8β,13β,14α,15-pentol; 20-Ethyl-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-3α,8,13,14α,15α-pentol(1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol; Jesaconine; Aconitane-3,8,13,14,15-pentol,20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1a,3a,6a,14a,15a,16b)-. Grades: >98%. CAS No. 509-20-6. Molecular formula: C25H41NO9. Mole weight: 499.59. | |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Alternative Names: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554. | |
| Acotiamide HCl | Acotiamide HCl is the hydrochloride salt of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: Acotiamide hydrochloride. CAS No. 185104-11-4. Molecular formula: C21H31ClN4O5S. Mole weight: 487.012. | |
| Acotiamide Impurity 5 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: 2-Amino-4-[(2-diisopropylaminoethyl)aminocarbonyl]-1,3-thiazole; 2-amino-N-(2-(diisopropylamino)ethyl)thiazole-4-carboxamide. CAS No. 206882-15-7. Molecular formula: C12H22N4OS. Mole weight: 270.395. | |
| Acotiamide Impurity 6 Maleate | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: N-(2-(diisopropylamino)ethyl)-2-(2,4,5-trimethoxybenzamido)thiazoleate. CAS No. 185103-81-5. Molecular formula: C26H36N4O9S. Mole weight: 580.653. | |
| Acotiamide Impurity 9 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: 4-Thiazolecarboxamide, 2-amino-N-(2-aminoethyl); 2-amino-N-(2-aminoethyl)-1,3-thiazole-4-carboxamide. CAS No. 948053-83-6. Molecular formula: C6H10N4OS. Mole weight: 186.24. | |
| Acotiamide Related Compound 12 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: 2-[N-(2,4,5-Trimethoxybenzoyl)amino]-4-(ethoxycarbonyl)-1,3-thiazole; Ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate. CAS No. 185105-98-0. Molecular formula: C16H18N2O6S. Mole weight: 366.388. | |
| ACP-5862 | ACP-5862 is a metabolite of Acalabrutinib, a second-generation BTK inhibitor used as a medication indicated for the treatment of non-Hodgkin lymphoma known as mantle cell lymphoma. Alternative Names: ACP 5862; ACP5862. CAS No. 2230757-47-6. Molecular formula: C26H23N7O3. Mole weight: 481.52. | |
| Ac-pSar10-OH | Ac-pSar10-OH can be used in the preparation of antibody-drug conjugates. Alternative Names: Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar. CAS No. 2857963-60-9. Molecular formula: C32H54N10O12. Mole weight: 770.83. | |
| Acridium, 9-chloro-10-methyl-, chloride (1:1) | Acridium, 9-chloro-10-methyl-, chloride (1:1) is a useful research chemical. Alternative Names: 9-Chloro-10-methylacridinium chloride; Acridinium, 9-chloro-10-methyl-, chloride. CAS No. 75586-67-3. Molecular formula: C14H11Cl2N. Mole weight: 264.1. | |
| Acrylonitrile-butadiene rubber | Acrylonitrile-butadiene rubber. CAS No. 9005-98-5. | |
| Ac-RYYRIK-NH2 TFA | Ac-RYYRIK-NH2 TFA is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin / orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Grades: 98%. Molecular formula: C46H71F3N14O11. Mole weight: 1053.13. | |
| Acuminatanol | Acuminatanol is a natural compound isolated from the herbs of Trichoscypha acuminata. Alternative Names: (2R,3R)-3,5,7-trihydroxy-2-[3,4,5-trihydroxy-2-[2,3,4-trihydroxy-6-[(2R,3R)-3,5,7-trihydroxy-4-oxo-2,3-dihydrochromen-2-yl]phenyl]phenyl]-2,3-dihydrochromen-4-one. Grades: 98.0%. CAS No. 948884-38-6. Molecular formula: C30H22O16. Mole weight: 638.49. | |
| Acyclovir L-Isoleucinate | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Alternative Names: 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl L-isoleucinate. Grades: > 95%. CAS No. 142963-63-1. Molecular formula: C14H22N6O4. Mole weight: 338.37. | |
| Adefovir Dipivoxil | Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV). Uses: Reverse transcriptase inhibitors. Alternative Names: ADEFOVIR DIPIVOXIL;142340-99-6;Hepsera;Preveon;Adefovir pivoxil;bis-POM PMEA;GS-0840;GS 840;GS 0840;Adefovir di(pivaloyloxymethyl) ester;GS-840;Adefovir dipivoxil [USAN];[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate;9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;DTXSID5046487;UNII-U6Q8Z01514;9-(2-((-Bis((pivaloylox. Grades: >98%. CAS No. 142340-99-6. Molecular formula: C20H32N5O8P. Mole weight: 501.47. | |
| Adefovir Dipivoxyl Impurity C | An impurity of Adefovir, a medication used for the treatment of infections with hepatitis B virus. Alternative Names: Mono-POM Ethyl Adefovir; Mono(pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester. Grades: > 95%. CAS No. 142341-04-6. Molecular formula: C16H26N5O6P. Mole weight: 415.39. | |
| Adenanthin | Adenanthin can induce differentiation of acute promyelocytic leukemia (APL) cells, which is isolated from the leaves of Rabdosia adenantha, it also can serve as what is to our knowledge the first lead natural compound for the development of Prx I -and Prx II - targeted therapeutic agents, which may represent a promising approach to inducing differentiation of APL cells. Uses: Anti-inflammatory, anti-tumour, anti-leukemic. Alternative Names: Actinodephnine Acuminatin Acuminatoside Adenanthin. Grades: >98%. CAS No. 111917-59-0. Molecular formula: C26H34O9. Mole weight: 490.6. | |
| Adipamidoxime | Adipamidoxime. Alternative Names: 1,4-Diamidoximobutane; N(1),N(6)-Dihydroxyhexanediimidamide. Grades: 95%. CAS No. 15347-78-1. Molecular formula: C6H14N4O2. Mole weight: 174.204. | |
| ADT-OH | ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Alternative Names: 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione; Desmethylanethol trithione; 3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-. CAS No. 18274-81-2. Molecular formula: C9H6OS3. Mole weight: 226.326. | |
| AEE-788 | AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. Alternative Names: AEE 788; AEE788; 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grades: >98%. CAS No. 497839-62-0. Molecular formula: C27H32N6. Mole weight: 440.595. | |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Alternative Names: AF353; AF-353; 2,4-Pyrimidinediamine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-; Ro 4; 5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyrimidinediamine. Grades: >98%. CAS No. 865305-30-2. Molecular formula: C14H17IN4O2. Mole weight: 400.21. | |
| AF38469 | AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and shows no activity against the NTR1 receptor. Alternative Names: AF 38469; AF-384694. CAS No. 1531634-31-7. Molecular formula: C15H11F3N2O3. Mole weight: 324.25. | |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: >98%. CAS No. 850140-72-6. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Alternative Names: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. Grades: 97%; ≥99% atom D. CAS No. 1313874-96-2. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. | |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Alternative Names: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. Grades: 95%. CAS No. 618061-76-0. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. | |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Alternative Names: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Grades: > 95%. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81. | |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-. Grades: > 95%. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Alternative Names: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: > 95%. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Alternative Names: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Grades: ≥95%. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. | |
| Afatinib Impurity J | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Alternative Names: (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (S,E)-4-(DIMETHYLAMINO)-N-(4-HYDROXY-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)BUT-2-ENAMIDE; (S,e)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide; Afatinib Impurity J; SCHEMBL17352060; SCHEMBL17352063; GSUSIQVMAQBROU-PCAWENJQSA-N; CS-0164268; E82037; (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: > 95%. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.4. | |
| Afuresertib | Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine / threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Alternative Names: GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B. Grades: 98%. CAS No. 1047644-62-1. Molecular formula: C18H17Cl2FN4OS. Mole weight: 427.32. | |
| Afzelechin | Afzelechin is isolated from the herbs of Celastrus orbiculatus. Uses: Anti-inflammatory activity. Alternative Names: (2R)-2α-(4-Hydroxyphenyl)chroman-3β,5,7-triol; [2R,3S,(+)]-3,4-Dihydro-2-(4-hydroxyphenyl)-2H-1-benzopyran-3,5,7-triol. Grades: 98%. CAS No. 2545-00-8. Molecular formula: C15H14O5. Mole weight: 274.3. | |
| Afzelechin 3-O-xyloside | Afzelechin 3-O-xyloside is purified from the barks of Cassipourea gerrardii. Alternative Names: (2S,3R,4S,5R)-2-[[(2R,3S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl]oxy]oxane-3,4,5-triol. Grades: 98.0%. CAS No. 512781-45-2. Molecular formula: C20H22O9. Mole weight: 406.38. | |
| Afzelechin-(4α?8)-epiafzelechin | Afzelechin-(4α→8)-epiafzelechin is a natural compound isolated from the herbs of Cassia javanica. Alternative Names: (2R,3R)-2-(4-hydroxyphenyl)-8-[(2R,3S,4S)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol. Grades: 97.5%. CAS No. 1383627-30-2. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Alternative Names: AG126; AG-126; Tyrphostin AG 126; UNII-7YA4AMD1JC; Tyrphostin A 10; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile. Grades: 95%. CAS No. 118409-62-4. Molecular formula: C10H5N3O3. Mole weight: 215.16. | |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Alternative Names: 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Molecular formula: C16H18N2O. Mole weight: 254.333. | |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Alternative Names: AG-1557; AG 1557; AG1557; N-(3-Iodophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 189290-58-2. Molecular formula: C16H14IN3O2. Mole weight: 407.211. | |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Alternative Names: Tyrphostin AG 490; AG-490; AG490. Grades: 0.98. CAS No. 133550-30-8. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| AG-879 | AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM). Alternative Names: α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide. CAS No. 148741-30-4. Molecular formula: C18H24N2OS. Mole weight: 316.5. | |
| AGK2 | AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Alternative Names: AGK-2; AGK 2; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide. Grades: >98%. CAS No. 304896-28-4. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.27. | |
| Aglain C | Aglain C, an organic alkaloid of natural origins, demonstrates anti-tumor activity, thus possessing potential application in diverse cancer treatment modalities. It elicits apoptosis, or cell death, in malignant cells, and exhibits anti-inflammatory properties. To ascertain its therapeutic value comprehensively, additional examination is warranted. Alternative Names: N-((S)-1-((2R,3S,4R,5R,10S)-5,10-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-3-phenyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine-4-carbonyl)pyrrolidin-2-yl)-2-methylbutanamide. Grades: 96%. CAS No. 177468-85-8. Molecular formula: C36H42N2O8. Mole weight: 630.727. | |
| Aglaxiflorin D | Aglaxiflorin D is an alkaloid compound isolated from the leaves of Aglaia abbriviata. Alternative Names: (R)-N-((S)-1-((2R,3S,4R,5R,10S)-5,10-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-3-phenyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine-4-carbonyl)pyrrolidin-2-yl)-2-hydroxy-2-methylbutanamide. Grades: 95%. CAS No. 269739-78-8. Molecular formula: C36H42N2O9. Mole weight: 646.727. | |
| Agrimol B | Agrimol B, a main active ingredient isolated from Agrimonia pilosa Ledeb, possesses insecticidal activity. Uses: Insecticidal. Alternative Names: (2S)-1-[3,5-Bis[[2,6-dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-2,4,6-trihydroxyphenyl]-2-methyl-1-butanone; 1-Butanone, 1-[3,5-bis[[2,6-dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-2,4,6-trihydroxyphenyl]-2-methyl-, (2S)-. Grades: >98%. CAS No. 55576-66-4. Molecular formula: C37H46O12. Mole weight: 682.75. | |
| Agrimonolide | Agrimonolide isolated from the herb of Agrimonia pilosa Ledeb. Alternative Names: (S)-3,4-Dihydro-6,8-dihydroxy-3-[2-(4-methoxyphenyl)ethyl]-1H-2-benzopyran-1-one; (3S)-6,8-Dihydroxy-3-[2-(4-methoxyphenyl)ethyl]-3,4-dihydro-1H-is ochromen-1-one. Grades: 98.5%. CAS No. 21499-24-1. Molecular formula: C18H18O5. Mole weight: 314.3. | |
| Agrimonolide 6-O-glucoside | Agrimonolide 6-O-glucoside is isolated from the herbs of Agrimonia pilosa. Alternative Names: Agrimonolide-6-O-glucopyranoside. Grades: 98.5%. CAS No. 126223-29-8. Molecular formula: C24H28O10. Mole weight: 476.5. | |
| AHK-Cu | AHK-Cu is a naturally-occurring peptide used for skin care and hair growth. | |
| Ajugol | Ajugol is an iridiod glucoside isolated from the roots of Rehmannia glutinosa. Uses: An iridiod glucoside. Alternative Names: (2S,3S,4R,5R,6S)-2-(hydroxymethyl)-6-{[(4aS,7S,7aR)-7-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl]oxy}tetrahydro-2H-pyran-2,3,4,5-tetrol. Grades: 98%. CAS No. 52949-83-4. Molecular formula: C15H24O9. Mole weight: 348.35. | |
| AK-7 | AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Alternative Names: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. Grades: >98%. CAS No. 420831-40-9. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35. | |
| Albatrelin A | Albatrelin A is a natural compound isolated from the fruiting bodies of Albatrellus ovinus. Alternative Names: 2,4-Dihydroxy-5-(3,7,11-trimethyl-2,6,10-dodecatriene-1-yl)-6-methylbenzoic acid methyl ester. Grades: 98.0%. CAS No. 1417805-15-2. Molecular formula: C24H34O4. Mole weight: 386.532. | |
| Albatrelin G | Albatrelin G is a natural compound isolated from the fruiting bodies of Albatrellus caeruleoporus, showing weak cytotoxic activity to cell lines HL-60, SMMC-7721, A-549, and MCF-7, in vitro. Alternative Names: 4-[(1R,2S,5R)-5-hydroxy-5-methyl-2-(6-methylhepta-1,5-dien-2-yl)cyclohexyl]-5-methylbenzene-1,3-diol. Grades: 98.0%. CAS No. 1630970-05-6. Molecular formula: C22H32O3. Mole weight: 344.495. | |
| Alcesefoliside | Alcesefoliside is a compound of the flavonoid class found in the herbs of Rubus alceaefolius Poir with cytoprotective activity. Alternative Names: Alcesefoliside; 124151-38-8; CHEMBL444468; 2-(3,4-dihydroxyphenyl)-3-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one; HY-N5049. Grades: >98%. CAS No. 124151-38-8. Molecular formula: C33H40O20. Mole weight: 756.7. | |
| aleplasinin | Aleplasinin is a selective and potent inhibitor of PAI-1 (Plasminogen activator inhibitor-1). It has been used in the treatment of Alzheimer's disease. Alternative Names: PAZ-417; PAZ 417; PAZ417. Grades: 95%. CAS No. 481629-87-2. Molecular formula: C28H27NO3. Mole weight: 425.52. | |
| Alepterolic acid | Alepterolic acid isolated from the rhizoma of Cibotium barometz (L.) J.Sm. Uses: Larvicidal properties. Alternative Names: (2E)-5-[(1S,4aR,6S,8aR)-6-Hydroxy-5,5,8a-trimethyl-2-methylenedec ahydro-1-naphthalenyl]-3-methyl-2-pentenoic acid. Grades: 0.985. CAS No. 63399-38-2. Molecular formula: C20H32O3. Mole weight: 320.5. | |
| Alfacalcidol EP Impurity B | Alfacalcidol EP Impurity B is an impurity of Alfacalcidol, which is a non-selective VDR activator medication. Alfacalcidol improves mechanical bone strength and bone mass and suppresses osteoclastic bone resorption in vivo. Alternative Names: 1-Belta-Calcidol; (1β,3β,5Z,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol; 1β-Calcidol; (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1β,3β-diol. CAS No. 63181-13-5. Molecular formula: C27H44O2. Mole weight: 400.65. | |
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