BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Amoxicilloic Acid Dimer (Mixture of Diastereomers) | One of the impurities of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Alternative Names: Amoxicilloic amoxilloic acid dimers 1, 2, 3, and 4; (2S,4S)-2-((R)-1-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-2-(((R)-2-((((2S,4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl)methyl)amino)-1-(4-hydroxyphenyl)-2-oxoethyl)amino)-2-oxoethyl)-5,5-dimethylthiazolidine-4-carboxylic Acid. Grades: 90%. Molecular formula: C31H40N6O9S2. Mole weight: 704.81. |  |
| AMOZ-[d5] | AMOZ-[d5] is the labelled analogue of AMOZ, which is a metabolite of Nitrofuran. Nitrofuran is a class of drugs commonly used as antibiotics. Alternative Names: 3-Amino-5-morpholin-4-ylmethyl-oxazolidin-2-one-D5; AMOZ-D5; 3-Amino-5-(4-morpholinylmethyl)-2-oxazolidinone-d5; 3-Amino-5-(4-morpholinylmethyl-d2)-2-Oxazolidinone-4,4,5-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 1017793-94-0. Molecular formula: C8H10D5N3O3. Mole weight: 206.25. | |
| Amrinone | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Alternative Names: Inamrinone;Wincoram;Inocor;Cordemcura;Win-40680;Win40680;3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grades: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20. | |
| Anacetrapib | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Alternative Names: MK-0859; MK 0859; MK0859; Anacetrapib. Grades: 0.99. CAS No. 875446-37-0. Molecular formula: C30H25F10NO3. Mole weight: 637.518. | |
| Anagrelide USP Related Compound A | An impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Alternative Names: Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate; Anagrelide hydrochloride USP Related Compound A; Glycine, N-[(6-amino-2,3-dichlorophenyl)methyl]-, ethyl ester; Anagrelide Related Compound A; N-[(6-Amino-2,3-dichlorophenyl)methyl]glycine ethyl ester; USP Anagrelide Related Impurity A; Ethyl N-(2,3-dichloro-6-aminobenzyl)glcycine; Ethyl (2-amino-5,6-dichlorobenzyl)aminoacetate; Ethyl N-(6-amino-2,3-dichlorobenzyl)glycine; N-(6-Amino-2,3-dichlorobenzyl)glycine ethyl ester. Grades: ≥95%. CAS No. 70406-92-7. Molecular formula: C11H14Cl2N2O2. Mole weight: 277.15. | |
| Andrographoside | Andrographoside is a natural diterpenoid found in the herbs of Andrographis paniculata. Due to its glucoside groups, andrographiside may act as strong antioxidants. Uses: Antioxidants. Alternative Names: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; 2(3H)-Furanone, 3-[2-[5-[(β-D-glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, [1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-; Andrographiside; Andrographolide 19-O-β-D-glucuronide. Grades: >96%. CAS No. 82209-76-5. Molecular formula: C26H40O10. Mole weight: 512.60. | |
| Andropanolide | Andropanolide is a natural diterpenoid found in the herbs of Andrographis paniculata (Burm. f.) Nees. Alternative Names: Isoandrographolide. Grades: >98%. CAS No. 869807-57-8. Molecular formula: C20H30O5. Mole weight: 350.45. | |
| Anemarrhena B | Anemarrhena B is a natural compound isolated from the herbs of Anemarrhena asphodeloides. Alternative Names: 2-[(1S)-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)propyl]-4-[3-(4-hydroxyphenyl)propyl]-5-methoxyphenol. Grades: 96.5%. CAS No. 1627521-95-2. Molecular formula: C32H34O6. Mole weight: 514.618. | |
| Anemarrhenasaponin A2 | Anemarrhenasaponin A2 is a steroidal saponins extracted from Anemarrhena Rhizoma. The rhizome of Anemarrhena asphodeloides Bunge (Liliaceae), so widely used in traditional chinese medicine, has been known to have an anti-diabetic activity, anti-platelet aggregation activity and diuretic activity. Alternative Names: β-D-Galactopyranoside, (2β,3β,5β,25S)-2-hydroxyspirostan-3-yl 2-O-β-D-glucopyranosyl-; (2β,3β,5β,25S)-2-Hydroxyspirostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; MarKogenin 3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside; Marcogenin 3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside; Schidigerasaponin F2. Grades: > 98%. CAS No. 117210-12-5. Molecular formula: C39H64O14. Mole weight: 756.92. | |
| Anemarrhenasaponin I | Anemarrhenasaponin I is a steroidal saponins extracted from Anemarrhena Rhizoma. The rhizome of Anemarrhena asphodeloides Bunge (Liliaceae), so widely used in traditional chinese medicine, has been known to have an anti-diabetic activity anti-platelet aggregation activity and diuretic activity. Alternative Names: β-D-Galactopyranoside, (3β,5β,15α)-15,22-dihydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-; (3β,5β,15α)-15,22-Dihydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; 22-Hydroxy-5β-furostan-3β,15α-diol 3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside; Anemarrhenasaponin 1. Grades: > 98%. CAS No. 163047-21-0. Molecular formula: C39H66O14. Mole weight: 758.93. | |
| Anemarrhenasaponin Ia | Anemarrhenasaponin Ia is a steroidal saponins extracted from Anemarrhena Rhizoma.The rhizome of Anemarrhena asphodeloides Bunge (Liliaceae) is a famous traditional chinese medicine with anti-diabetic activity, anti-platelet aggregation activity and diuretic activity. Alternative Names: β-D-Galactopyranoside, (3β,5β,15α)-15-hydroxy-22-methoxyfurostan-3-yl 2-O-β-D-glucopyranosyl-; (3β,5β,15α)-15-Hydroxy-22-methoxyfurostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; Anemarrhenasaponin 1a; Anemarrhenasaponin Ia. Grades: > 98%. CAS No. 221317-02-8. Molecular formula: C40H68O14. Mole weight: 772.96. | |
| Anemarrhenasaponin III | Anemarrhenasaponin III is a steroidal saponins extracted from Anemarrhena Rhizoma. Alternative Names: β-D-Galactopyranoside, (3β,5β,15α,25S)-15-hydroxyspirostan-3-yl 2-O-β-D-glucopyranosyl-; β-D-Galactopyranoside, (3β,5β,15α,25S)-15-hydroxyspirostan-3-yl 2-O-β-D-glucopyranosyl-. Grades: > 98%. CAS No. 163047-23-2. Molecular formula: C39H64O14. Mole weight: 756.92. | |
| Anemarsaponin BIII | Anemarsaponin BIII is extracted from the rhizomes of Anemarrhena asphodeloides Bunge. Alternative Names: Anemarsaponin B3; Pseudoprototimosaponin AIII; Timosaponin B. Grades: >98%. CAS No. 142759-74-8. Molecular formula: C45H74O18. | |
| Anemarsaponin E | Anemarsaponin E is extracted from the rhizomes of Anemarrhena asphodeloides Bunge. Alternative Names: (3beta,5beta,25S)-26-(beta-D-glucopyranosyloxy)-22-methoxyfurostan-3-yl 2-O-beta-D-glucopyranosyl-beta-D-Galactopyranoside; Timosaponin B I; AneMarsaponin BI. Grades: >98%. CAS No. 136565-73-6. Molecular formula: C46H78O19. | |
| Anemoside A3 | Pulchinenoside A3 is extracted from the roots of Pulsatilla chinensis. It is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases. Alternative Names: (3beta,4alpha)-3-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl]oxy]-23-hydroxylup-20(29)-en-28-oic acid; Pulchinenoside A; Anemoside A3. Grades: >98%. CAS No. 129724-84-1. Molecular formula: C41H66O12. Mole weight: 751. | |
| Angelol A | Angelol A is a coumarin isolated from Angelica pubescens. It is passive diffusion as the dominating process in Caco-2 cell monolayer model. Alternative Names: [(1R,2S)-1,3-dihydroxy-1-(7-methoxy-2-oxochromen-6-yl)-3-methylbutan-2-yl] (Z)-2-methylbut-2-enoate. Grades: 0.98. CAS No. 19625-17-3. Molecular formula: C20H24O7. Mole weight: 376.4. | |
| Angelol B | Angelol B is a coumarin isolated from Angelica pubescens. It is passive diffusion as the dominating process in Caco-2 cell monolayer model. Grades: 98%. CAS No. 83156-04-1. Molecular formula: C20H24O7. Mole weight: 376.4. | |
| Angeloyl gomisin H | Angeloyl gomisin H is an intriguing natural compound isolated from Schisandra chinensis, showcasing remarkable anti-inflammatory and antioxidant properties, aiding in studying inflammatory afflictions, including arthritis. Alternative Names: Angeloylgomisin H; (2Z)-2-Methyl-2-butenoic acid (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester. Grades: >98%. CAS No. 66056-22-2. Molecular formula: C28H36O8. Mole weight: 500.58. | |
| Angeloylisogomisin O | Angeloylisogomisin O isolated from the fruits of Schizandra chinensis. Alternative Names: (6S,7S,8R)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrob enzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-8-yl (2Z)- 2-methyl-2-butenoate. Grades: > 95%. CAS No. 83864-70-4. Molecular formula: C28H34O8. Mole weight: 498.6. | |
| Angenomalin | Angenomalin is found in the roots of Angelica dahurica. Alternative Names: Majurin. Grades: > 95%. CAS No. 18199-64-9. Molecular formula: C14H12O3. Mole weight: 228.24. | |
| Angiotensin (1-7) (acetate) | Angiotensin (1-7) (acetate) is an angiotensin I metabolite. Angiotensin (1-7) (acetate) inhibits purified canine ACE activity (IC50 = 0.65 μM). Angiotensin (1-7) (acetate) acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin (1-7) (acetate) blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Alternative Names: 5-L-isoleucine-1-7-angiotensin II; Angiotensin Fragment 1-7 (acetate). Grades: 98%. Molecular formula: C43H66N12O13. Mole weight: 959.06. | |
| Anhydroglycinol | Anhydroglycinol is isolated from the herbs of Derris robusta. Alternative Names: 3,9-Dihydroxypterocarp-6a-en; 6H-[1]benzofuro[3,2-c]chromene-3,9-diol. Grades: 98%. CAS No. 67685-22-7. Molecular formula: C15H10O4. Mole weight: 254.2. | |
| Anidulafungin Impurity B | Anidulafungin Impurity B is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23. | |
| Anidulafungin Impurity D | Anidulafungin Impurity D is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C59H75N7O17. Mole weight: 1154.28. | |
| Anidulafungin Impurity E | Anidulafungin Impurity E is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23. | |
| Anidulafungin Impurity F | Anidulafungin Impurity F is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C82H95N7O19. Mole weight: 1482.69. | |
| Anisofolin A | Anisofolin A is isolated from the herbs of Leonurus japonicus. Alternative Names: Apigenin 7-O-(3'',6''-di-O-E-p-coumaroyl)-beta-D-glucopyranoside. Grades: 98%. CAS No. 83529-71-9. Molecular formula: C39H32O14. Mole weight: 724.7. | |
| Ankaflavin | A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Alternative Names: 2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxooctyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-. Grades: > 95%. CAS No. 50980-32-0. Molecular formula: C23H30O5. Mole weight: 386.49. | |
| Antennapedia Peptide TFA | Antennapedia Peptide, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptides. Alternative Names: L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-D-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine trifluoroacetic acid. Grades: 98%. Molecular formula: C106H169F3N34O22S. Mole weight: 2360.82. | |
| Anthracen-9-ol | Anthracen-9-ol is a useful research chemical. Alternative Names: Anthranol; 9-Anthracenol; 9-Anthrol. Grades: 95 %. CAS No. 529-86-2. Molecular formula: C14H10O. Mole weight: 194.23. | |
| Antidesmone | Antidesmone isolated from the barks of Antidesma membranaceum. Uses: Fungitoxic activity. Alternative Names: (5S)-3-Methoxy-2-methyl-5-octyl-1,5,6,7-tetrahydro-4,8-quinolined ione. Grades: 95%. CAS No. 222629-77-8. Molecular formula: C19H29NO3. Mole weight: 319.4. | |
| Antiquorin | Antiquorin is a natural diterpenoid compound found in several plants. Alternative Names: (13R)-13-Hydroxy-ent-atis-16-ene-3,14-dione. Grades: >95%. CAS No. 125356-08-3. Molecular formula: C20H28O3. Mole weight: 316.43. | |
| AOZ-[d4] | AOZ-[d4] is the labelled analogue of AOZ, which is a metabolite of Furazolidone. Alternative Names: AOZ-d4; 3-Amino-2-oxazolidinone-d4; 3-Amino-1,3-oxazolidin-2-one-d4; NSC 111187-d4; NSC 196570-d4; NSC 38250-d4; Vetranal-d4. Grades: ≥97%; ≥97% atom D. CAS No. 1188331-23-8. Molecular formula: C3H2D4N2O2. Mole weight: 106.12. | |
| Apatinib mesylate | Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Uses: Antineoplastic agents. Alternative Names: YN968D1. Grades: >98%. CAS No. 1218779-75-9. Molecular formula: C25H27N5O4S. Mole weight: 493.58. | |
| Apigenin 7-O-methylglucuronide | Apigenin 7-O-methylglucuronide is a flavonoid glycoside isolated from Physocarpus capitatus. Alternative Names: (2S,3S,4S,5R,6S)-Methyl 3,4,5-trihydroxy-6-((5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylate. Grades: 98.0%. CAS No. 53538-13-9. Molecular formula: C22H20O11. Mole weight: 460.4. | |
| Apilimod mesylate | The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Alternative Names: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7. | |
| Apimostinel | Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Alternative Names: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grades: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60. | |
| Apixaban Impurity 46 | An impurity of Apixaban, which is a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Alternative Names: 3-chloro-1-(2-nitrophenyl)-1,2,5,6-tetrahydropyridin-2-one; 3-Chloro-1-(2-nitrophenyl)-5,6-dihydropyridin-2(1H)-one; Apixaban Related Compound 5. Grades: 95%. CAS No. 2219376-48-2. Molecular formula: C11H9ClN2O3. Mole weight: 252.65. | |
| APO-10 | APO-10 is a novel non-ionic detergent useful for plasmid DNA isolation. Alternative Names: Decyl(Dimethyl)phosphine Oxide; Dimethyldecylphosphine oxide. Grades: 95%. CAS No. 2190-95-6. Molecular formula: C12H27OP. Mole weight: 218.32. | |
| Apremilast | Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Alternative Names: (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004. Grades: >98%. CAS No. 608141-41-9. Molecular formula: C22H24N2O7S. Mole weight: 460.50. | |
| Aprepitant | Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent. Alternative Names: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436. Grades: 98%. CAS No. 170729-80-3. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. | |
| APY0201 | APY0201, an effective IL-12/23 inhibitor, has been found to have potential use in the treatment of inflammation. IC50 = 5.2 nM. Alternative Names: APY0201; APY-0201; APY 0201. Grades: 98%. CAS No. 1232221-74-7. Molecular formula: C23H23N7O. Mole weight: 413.48. | |
| APY29 | Allosteric modulator of IRE1α. Inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α ribonuclease activity. Alternative Names: APY29; APY-29; APY 29; N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine. Grades: >98%. CAS No. 1216665-49-4. Molecular formula: C17H16N8. Mole weight: 332.36. | |
| AR-12 Hydrochloride | OSU 03012, a Phenanthren derivative, has been found to be a PDPK1 inhibitor that could probably be an effctive antitumor agent. It is still under Phase I trail for solid-tumour. IC50: 5 μM. Alternative Names: OSU-03012; AR-12; AR 12; AR12; OSU 03012; OSU03012; PDK1 inhibitor AR-12; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide. Grades: 98%. CAS No. 1471979-81-3. Molecular formula: C26H19F3N4O. Mole weight: 460.46. | |
| AR-AO 14418-[d3] | AR-AO 14418-[d3] is a labelled analogue of AR-AO 14418, a Glycogen Synthase Kinase 3β (GSK-3β) inhibitor. Alternative Names: AR-AO 14418-d3; AR-A014418-d3. CAS No. 1216908-63-2. Molecular formula: C12H9D3N4O4S. Mole weight: 311.33. | |
| Arbidol hydrochloride | Arbidol is an antiviral agent used for the treatment of influenza infection in Russia and China. It has been used against influenza A and B viruses, and hepatitis C virus (HCV). It has been shown that ARB could inhibit COVID-19 infection through interfering the release of SARS-CoV-2 from intracellular vesicles. It can be used to treat trypanosomiasis in livestock. Alternative Names: Arbidol HCl; Umifenovir hydrochloride; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride. Grades: >98%. CAS No. 131707-23-8. Molecular formula: C22H26BrClN2O3S. Mole weight: 513.88. | |
| Arborinine | Arborinine is an alkaloid isolated from Erthela bahiensis. Arborinine was shown to inhibit splenocytes proliferation under ConA or PWM stimulation and promote apoptosis on splenocytes and thymocytes stimulated with PWM in 24h. It also decreases production of Interleukin-10 by splenocytes and thymocytes stimulated with ConA or PWM. Alternative Names: 1-hydroxy-2,3-dimethoxy-10-methylacridin-9-one. Grades: 98.5%. CAS No. 5489-57-6. Molecular formula: C16H15NO4. Mole weight: 285.299. | |
| Argatroban Impurity B | Argatroban Impurity B is an impurity of Argatroban, which is a synthetic thrombin inhibitor and antithrombotic agent. Alternative Names: Argatroban Impurity B (Mixture of Diastereomers); 4-Methylpiperidine-2-carboxylic Acid, (2R,4R)-1-((2S)-5-amino-2-((3-methyl-1,2,3,4-tetrahydroquinoline)-8-sulfonamido)pentanoyl)-. Grades: 95%. CAS No. 188659-43-0. Molecular formula: C22H34N4O5S. Mole weight: 466.59. | |
| Argatroban monohydrate | Argatroban is an anticoagulant that acts as a potent, seletive, univalent direct inhibitor of thrombin. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Alternative Names: (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid hydrate; MCI-9038; MCI 9038; MCI9038; MD805; MD-805; MD 805; DK-7419; DK 7419; DK7419; GN1600; GN-1600; GN 1600; MMTQAP; MPQA; OM 805; Slonnon; Argipidine; Argatroban monohydrate. Grades: 98%. CAS No. 141396-28-3. Molecular formula: C23H38N6O6S. Mole weight: 526.65. | |
| Arimoclomol maleate | Arimoclomol is a heat shock protein amplifier. It has been granted Fast Track designation by FDA for the treatment of myotrophic lateral sclerosis (ALS). Alternative Names: (2R)-Arimoclomol Maleic Acid. CAS No. 289893-26-1. Molecular formula: C18H24ClN3O7. Mole weight: 429.9. | |
| Aripiprazole-[d8] | Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. Uses: An isotopic labelled form of aripiprazole which is an antagonist of dopamine-2 receptor and a partial agonist of 5-ht1a receptor that could be used as an antipsychotic agent. Alternative Names: Aripiprazole D8; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; Aripiprazole-d8; OPC 14597-d8; 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl-2,2,3,3,5,5,6,6-d8]butoxy]-3,4-dihydro-. Grades: 97%; ≥97% atom D. CAS No. 1089115-06-9. Molecular formula: C23H19D8Cl2N3O2. Mole weight: 456.43. | |
| Aripiprazole EP Impurity D | An impurity of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Alternative Names: 2-Deschloro Aripiprazole; 7-[4-[4-(3-chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydroquinolin-2(1H)-one. CAS No. 203395-82-8. Molecular formula: C23H28ClN3O2. Mole weight: 413.94. | |
| Aripiprazole Impurity 4 | A metabolite of Aripiprazole. Alternative Names: 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole; 7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)-1-(4-((2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy)butyl)-3,4-dihydroquinolin-2(1H)-one. Grades: > 95%. CAS No. 1424857-63-5. Molecular formula: C36H42Cl2N4O4. Mole weight: 665.67. | |
| Aripiprazole lauroxil | Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes plc. Aripiprazole lauroxil is applicated as long-acting injectable atypical antipsychotic for the treatment of schizophrenia. It is an N-acyloxymethyl prodrug of aripiprazole. Uses: Schizophrenia. Alternative Names: Aristada; RDC-3317; RDC 3317; RDC3317; UNII-B786J7A343; ALKS 9070; ALKS9070; ALKS-9070; ALKS 9072; ALKS-9072; ALKS9072; [7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate. Grades: 98%. CAS No. 1259305-29-7. Molecular formula: C36H51Cl2N3O4. Mole weight: 660.72. | |
| Aristolochic Acid B | Aristolochic acids occur in Aristolochiaceae and in butterflies feeding on these plants. One of a group of fourteen known, substituted 1-phenanthrenecarboxylic acids. Alternative Names: Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 6-nitro-; 6-Nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid II; 3,4-(Methylenedioxy)-10-nitrophenanthrene-1-carboxylic acid. Grades: >98%. CAS No. 475-80-9. Molecular formula: C16H9NO6. Mole weight: 311.25. | |
| Aristololactam | The cytotoxic potency of Aristololactam I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase 3-dependent pathway. Alternative Names: aristololactam; 8-methoxy[1,3]benzodioxolo[6,5,4-cd]benzo[f]indol-5(6H)-one. Grades: >98%. CAS No. 13395-02-3. Molecular formula: C17H11NO4. Mole weight: 293.27. | |
| Arjunic acid | Arjunic acid isolated from the stem bark of Terminalia arjuna. It shows activity against Gram-positive and Gram-negative bacteria. Uses: A strong antioxidant and a free radical scavenger. Alternative Names: 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid. Grades: 95%. CAS No. 31298-06-3. Molecular formula: C30H48O5. Mole weight: 488.7. | |
| Arjunolic acid | Arjunolic acid is a natural triterpenoid isolated from the fruits of Terminalia chebula Retz, it has antioxidant properties and plays protective roles against chemically induced organ pathophysiology. Arjunolic acid can protect cardiac tissues from both extrinsic and intrinsic cell death pathways. Uses: Antioxidant. Alternative Names: 2,3,23-Trihydroxy-12-oleanen-28-oic acid. Grades: >98%. CAS No. 465-00-9. Molecular formula: C30H48O5. Mole weight: 488.7. | |
| Armepavine | Armepavine is isolated from Nelumbo nucifera. It exhibits anti-inflammatory and immunosuppressive effects. Alternative Names: (-)-Armepavine; Evoeuropine. Grades: >98%. CAS No. 524-20-9. Molecular formula: C19H23NO3. Mole weight: 313.4. | |
| ARN-3236 | ARN-3236 is an orally available and selective inhibitor of salt-inducible kinase 2 (SIK2). Study shows that ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. Alternative Names: 3-(2,4-dimethoxyphenyl)-4-(thiophen-3-yl)-1H-pyrrolo[2,3-b]pyridine; 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine. CAS No. 1613710-01-2. Molecular formula: C19H16N2O2S. Mole weight: 336.41. | |
| Arnebin 1 | Arnebin 1 is found in Arnebia euchroma. Alternative Names: Dmask; beta,beta-Dimethylacrylshikonin; Dimethylacrylshikonin; Isoarnebin I. Grades: > 95%. CAS No. 5162-1-6. Molecular formula: C21H22O6. Mole weight: 370.39. | |
| Aromadendrin 7-O-rhamnoside | Aromadendrin 7-O-rhamnoside, a flavonoid compound present in numerous plant species, exhibits considerable efficacy as an antioxidant and anti-inflammatory agent, and is considered to have therapeutic potential in diverse pathological conditions including cancer and diabetes. Its efficacy can be attributed to its natural composition making it a plausible resource for discovery of novel pharmacological targets in the nutraceutical and pharmaceutical sectors. Alternative Names: (2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one. Grades: 97.5%. CAS No. 69135-41-7. Molecular formula: C21H22O10. Mole weight: 434.39. | |
| ARS-1323 | ARS-1323 is an inhibitor of mutant K-ras G12C. Alternative Names: ARS-1323; ARS 1323; ARS1323; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one. CAS No. 1698024-73-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ARS-1620 | ARS-1620 is a potent and selective KRAS-G12C inhibitor. ARS-1620 achieves rapid and sustained in vivo target occupancy to induce tumor regression. Alternative Names: ARS-1620; ARS 1620; ARS1620; BCP29125; BCP 29125; BCP-29125; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one sulfane. CAS No. 1698055-85-4. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ARS-1630 | ARS-1630 is the R-enantiomer of ARS-1620. It is an inhibitor of mutant K-ras G12C. Alternative Names: ARS-1630; ARS 1630; ARS1630; (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one. CAS No. 1698055-86-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ART558 | ART558 is a nanomolar potent, selective, allosteric DNA polymerase activity of Polθ inhibitor with IC50 of 7.9 nM. ART558 can be used in cancer research. Alternative Names: GLXC-26260. CAS No. 2603528-97-6. Molecular formula: C21H21F3N4O2. Mole weight: 418.41. | |
| ART812 | ART812 is an orally active DNA polymerase Polθ inhibitor with IC 50 of 7.6 nM. ART812 also significantly inhibited PARP-resistant BRCA1 mutant tumor growth in rats. Alternative Names: HY-139289. CAS No. 2607138-82-7. Molecular formula: C19H16ClF4N3O4. Mole weight: 461.79. | |
| Artemetin acetate | Artemetin acetate is isolated from the herbs of Achillea millefolium L. Alternative Names: 2-(3,4-Dimethoxyphenyl)-3,6,7-trimethoxy-4-oxo-4H-chromen-5-yl acetate. Grades: 97.5%. CAS No. 95135-98-1. Molecular formula: C22H22O9. Mole weight: 430.4. | |
| Artemyriantholide D | Artemyriantholide D is isolated from Artemisia myriantha. Grades: 98.0%. CAS No. 421558-76-1. Molecular formula: C30H36O6. Mole weight: 492.612. | |
| AS101 | AS101 is a synthetic non-toxic tellurium derivative, structurally similar to cisplatin, with immuno-modulating, antiviral, and hair growth-promoting activities. This agent is also a potent inducer of IL-1 and IL-6. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced alopecia. Alternative Names: AS-101; IVX-Q-101; PRX-0001; PRX-0002; PRX-001; WAX-120337; IVXQ-101; AS101; IVXQ101; PRX0001; PRX0002; PRX001;WAX120337; AS 101; IVX Q 101; PRX 0001; PRX 0002; PRX 001; WAX 120337; IVXQ 101; US brand name: Ossirene; IVX-Q-101. Ammonium trichloro(dioxoethylene-O,O') tellurate. CAS No. 106566-58-9. Molecular formula: C2H4Cl3O2Te.H4N. Mole weight: 312.049. | |
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