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Brinzolamide Related Compound C
Brinzolamide Related Compound C is an isomer of Brinzolamide. Alternative Names: (S)-Brinzolamide; (S)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 4862. Grades: > 95%. CAS No. 154127-19-2. Molecular formula: C12H21N3O5S3. Mole weight: 383.51.
Britannilactone
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively. Alternative Names: Desacetylinulicin. Grades: >98%. CAS No. 33620-72-3. Molecular formula: C15H22O4. Mole weight: 266.33.
Brivanib
Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: BMS540215; BMS-540215; BMS 540215. CAS No. 649735-46-6. Molecular formula: C19H19FN4O3. Mole weight: 370.37756.
Brivanib alaninate
Brivanib alaninate is the alaninate ester of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: BMS-582664; BMS582664; BMS 582664. CAS No. 649735-63-7. Molecular formula: C22H24FN5O4. Mole weight: 441.45.
Bromobenzene-[d5]
Bromobenzene-[d5] can be used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents. Alternative Names: Bromobenzene D5; Bromo(2H5)benzene; Pentadeuterobromobenzene. Grades: 99%. CAS No. 4165-57-5. Molecular formula: C6BrD5. Mole weight: 162.04.
(Bromomethyl-[d2])cyclopropane-[1-d]
(Bromomethyl-[d2])cyclopropane-[1-d]. Uses: Labelled bromomethylcyclopropane. Alternative Names: 1-(Bromomethyl-d2)cyclopropane-d1; Cyclopropanemethyl-d3 Bromide; Cyclopropylcarbinyl-d3 Bromide; Cyclopropylmethyl-d3 Bromide. Grades: 98% atom D. CAS No. 1219799-17-3. Molecular formula: C4H4D3Br. Mole weight: 138.02.
Bromuron-[d6]
Bromuron-[d6] is a deuterium labelled Bromuron, a urea herbicide. Alternative Names: Bromuron-d6. Molecular formula: C9H5D6BrN2O. Mole weight: 249.14.
Bropirimine
Bropirimine is an immunostimulant as well as anticancer agent and has been found to exhibit direct antitumor activity. Alternative Names: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone. Grades: ≥96% by HPLC. CAS No. 56741-95-8. Molecular formula: C10H8BrN3O. Mole weight: 266.09.
Broussonin B
Broussonin B is a natural phenols found in the branch of Broussonetia papyrifera, it has moderate inhibitory activities against a chymotrypsin-like activity of the proteasome. Alternative Names: 4-[3-(4-Hydroxyphenyl)propyl]-3-methoxyphenol. Grades: >98%. CAS No. 73731-86-9. Molecular formula: C16H18O3. Mole weight: 258.32.
Broussonin C
Broussonin C is a natural phenol found in the branch of Broussonetia papyrifera, it exerts simple reversible slow-binding inhibition against diphenolase. Alternative Names: 4-[3-[4-Hydroxy-3-(3-methyl-2-butenyl)phenyl]propyl]-1,3-benzenediol;1,3-Benzenediol,4-[3-[4-hydroxy-3-(3- Methyl-2-butenyl)phenyl]propyl]-. Grades: >98%. CAS No. 76045-49-3. Molecular formula: C20H24O3. Mole weight: 312.41.
Bruceine D
Bruceine D is extracted from the barks of Ailanthus altissima. It is an inhibitor of hepatocellular carcinoma growth and inhibits the growth of three pancreatic cancer cell lines, which acts by targeting β-catenin/jagged1 pathways. It also induces cytotoxicity in Capan-2 cells by inducing cellular apoptosis involving the mitochondrial pathway. It may be used as a lead compound for new viricides, or a natural viricide. Alternative Names: Nsc318801; (1beta,11beta,12alpha,15beta)-13,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-ene-2,16-dione; Picras-3-ene-2,16-dione,13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1b,11b,12a,15b)-; (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,11S,11aS)-1,2,3a,4,11-pentahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,7,7a,11,11a,11b-decahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH)-dione. Grades: 98.5%. CAS No. 21499-66-1. Molecular formula: C20H26O9. Mole weight: 410.42.
Bruceine E
Bruceine E is extracted from the seeds of Brucea javanica (L.) Merr. It could reduce blood glucose concentration remarkably and may be used as an insulin secretagogue. Alternative Names: 13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one; 20-Deoxybruceine F; 2-O-Demethylbruceine M; 5H-3,11c-beta-(Epoxymethano)phenanthro(10,1-bc)pyran-5-one, 1,2,3,3a,4,6a-beta,7,7a-alpha,10,11,11a,11b-alpha-dodecahydro-1-beta,2-alpha,3a-beta,4-beta,10-alpha,11-beta-hexahydroxy-3-alpha,8,11a-beta-trimethyl-, (+)-; Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1beta,2alpha,11beta,12alpha,15beta)-. Grades: 98.0%. CAS No. 21586-90-3. Molecular formula: C20H28O9. Mole weight: 412.43.
Brusatol
Brusatol is a triterpenoid isolated from the Brucea javanica plant. Brusatol acts as an Nrf2 inhibitor with anticancer activity. Uses: Anti-tumor. Alternative Names: (+)-Brusatol; Yatansin. Grades: >98%. CAS No. 14907-98-3. Molecular formula: C26H32011. Mole weight: 520.53.
Bryodulcosigenin
Bryodulcosigenin is a triterpenoid with anti-inflammatory effect. Alternative Names: Bryodulocosigenin. Grades: 0.98. CAS No. 4965-97-3. Molecular formula: C30H50O4. Mole weight: 474.72.
Bryonamide A
Bryonamide A is an alkaloid isolated from Bryonia aspera. Alternative Names: 4-Hydroxy-N-(2-hydroxyethyl)benzamide; N-(2-Hydroxyethyl)-4-hydroxybenzamide; Benzamide, 4-hydroxy-N-(2-hydroxyethyl)-. Grades: 98.5%. CAS No. 75268-14-3. Molecular formula: C9H11NO3. Mole weight: 181.191.
BS-181 HCl
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Alternative Names: BS-181 HCl; BS 181 HCl; BS181 HCl. Grades: >98%. CAS No. 1397219-81-6. Molecular formula: C22H32N6.HCl. Mole weight: 416.99.
Buclizine hydrochloride
Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family. Alternative Names: Buclizine dihydrochloride; 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride. Grades: > 98%. CAS No. 129-74-8. Molecular formula: C28H35Cl3N2. Mole weight: 505.952.
Bulleyaconitine A
Bulleyaconitine A is an alkaloid found in Aconitum bulleyanum. It has analgesic and anti-inflammatory properties and has been used for the treatment of chronic pain and rheumatoid arthritis. Uses: Bulleyaconitine a, an active indegrent from aconitum bulleyanum diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis. Alternative Names: ((1-α,6-α,14-α,16-β)-8-(acetyloxy)-20-ethyl-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl)(4-methoxyphenyl)-methanone; 20-ethyl-13g-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl](4-methoxyphenyl)-methanone, [(1α,6α,14α,16β) -8-(acetyloxy)-. Grades: >98%. CAS No. 107668-79-1. Molecular formula: C35H49NO9. Mole weight: 627.76.
Bulleyanin
Bulleyanin is a natural diterpenoid found in the herbs of Rabdosia bulleyana, which can be solved in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. Alternative Names: (1α,3β,5β,7β,8α,9β,10α,11β,12α,13α)-12-Hydroxy-15-oxokaur-16-ene- 1,3,7,11-tetrayl tetraacetate. Grades: >97%. CAS No. 123043-54-9. Molecular formula: C28H38O10. Mole weight: 534.6.
Bumetanide EP Impurity B
Bumetanide EP Impurity B is a metabolite of Bumetanide. Bumetanide is a diuretic to eliminate edema caused by heart failure. Alternative Names: Desbutyl Bumetanide; Bumetanide Related Compound A (USP); 3-Amino-5-(aminosulphonyl)-4-phenoxybenzoic acid; PF 1578; 3-Amino-4-phenoxy-5-sulfamoylbenzoic Acid. Grades: 95%. CAS No. 28328-54-3. Molecular formula: C13H12N2O5S. Mole weight: 308.31.
Buparvaquone
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. It is a promising compound for the therapy and prophylaxis of all forms of theileriosis. It has been shown to have antileishmanial activity in vitro. It can be used to treat bovine East Coast fever protozoa in vitro, along with the only other substance known - Peganum harmala. It is the only really efficient commercial therapy product in bovine theileriosis, where it has been used since the late 1980s. Alternative Names: Butalex. Grades: >98%. CAS No. 88426-33-9. Molecular formula: C21H26O3. Mole weight: 326.43.
Buquinolate-[13C3]
Buquinolate-[13C3] is an isotope labelled Buquinolate. Buquinolate is an anticoccidial agent approved by the U.S. FDA for use in broilers and layers, but later withdrawn from the market. Alternative Names: Buquinolate-13C3; 4-Hydroxy-6,7-diisobutoxyquinoline-3,4-13C2-3-carboxylic acid-13C ethyl ester. Molecular formula: C17[13C]3H27NO5. Mole weight: 364.42.
Butamirate Impurity 1
an impurity of Butamirate. Alternative Names: Benzeneacetamide, N,N,α-triethyl-; Butyramide, N,N-diethyl-2-phenyl- (6CI,7CI). Grades: > 95%. CAS No. 92321-53-4. Molecular formula: C15H22O. Mole weight: 218.34.
Butenafine-[13C,d3] HCl
Butenafine-[13C,d3] HCl is a labelled analogue of Butenafine HCl. Butenafine is a synthetic benzylamine antifungal. Alternative Names: Butenafine-13C-d3 HCl; Butenafine-13C,d3 HCl; Butenafine-13C,d3 hydrochloride; KP363-13C,d3 hydrochloride; KP363-13C,d3 HCl. Molecular formula: C22[13C]H25D3ClN. Mole weight: 357.94.
Butin
Butin is a natural flavonoid found in the seeds of Cassia tora. Butin has activity of antioxidant, which can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction. Uses: Antioxidant. Alternative Names: (2S)-7,3',4'-Trihydroxyflavanone;(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1 -benzopyran-4-one;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydro xy-, (S)-. Grades: >97%. CAS No. 492-14-8. Molecular formula: C15H12O5. Mole weight: 272.25.
BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Alternative Names: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95.
BX-795
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Alternative Names: BX 795; BX795. Grades: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47.
Byakangelicin
Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Alternative Names: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. Grades: >98%. CAS No. 482-25-7. Molecular formula: C17H18O7. Mole weight: 334.32.
Byakangelicol
Byakangelicol is a furanocoumarin derivative which shows inhibitory effects against P-glycoprotein at the blood-brain barrier. It acts as an anti-proliferative agent causing G2/M arrest in melanoma cells. Alternative Names: (R)-(+)-9-(2,3-Epoxy-3-methylbutoxy)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one. Grades: >98%. CAS No. 26091-79-2. Molecular formula: C17H16O6. Mole weight: 316.3.
BzATP triethylammonium salt
The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5-10 fold greater potency than ATP with EC50 of 0.7 μM. It also exhibits partial agonist activity at P2X1 and P2Y1 receptors. BzATP can also be used as a photoaffinity probe to study adenine nucleotide binding to ATPases. Alternative Names: BzATP; Benzoylbenzoic adenosine 5'-triphosphate. Grades: ≥95%. CAS No. 112898-15-4. Molecular formula: C30H39N6O15P3. Mole weight: 816.6.
C34 is a TLR4 inhibitor. Alternative Names: C 34; C-34; TLR4-IN-C34; 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate; Isopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside; α-D-Glucopyranoside, 1-methylethyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; Isopropyl 3,4,6-tri-O-acetyl-α-D-GlcNAc; Toll-Like Receptor 4-C34; TLR-C 34; TLR-C34; Isopropyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate; Isopropyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranoside. Grades: ≥98%. CAS No. 40592-88-9. Molecular formula: C17H27NO9. Mole weight: 389.40.
C646
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. Alternative Names: C646; C-646; C 646. Grades: >98%. CAS No. 328968-36-1. Molecular formula: C24H19N3O6. Mole weight: 445.42.
CA-4948
CA-4948 is a potent and selective IRAK4 inhibitor that can be used for the treatment of cancers with dysregulated TLR/MYD88/IRAK4 signaling. Alternative Names: CA-4948; CA 4948; CA4948; 6'-Amino-N-[2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl][2,3'-bipyridine]-6-carboxamide. Grades: >98%. CAS No. 1801343-74-7. Molecular formula: C21H19N7O3. Mole weight: 417.429.
Cabazitaxel intermediate
Cabazitaxel intermediate is extracted from the barks of Taxus yunnanensis. Alternative Names: 5-[(2α,5β,7β,10β,13α)-4-Acetoxy-2-(benzoyloxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-13-yl] 3-(2-methyl-2-propanyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate; 3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) ester, (4S,5R)-; Cabazitaxel N-2; Docetaxel Impurity 62. Grades: 97.0%. CAS No. 1354900-65-4. Molecular formula: C51H59NO15. Mole weight: 926.02.
Cabergoline Impurity A
6-Allyl-8β-carboxyergoline is a metabolite of cabergoline which is a dopamine D2-receptor agonist. Alternative Names: (8β)-6-(2-Propen-1-yl)-ergoline-8-carboxylic Acid; 6-(2-Propenyl)dihydrolysergic Acid; FCE 21589. Grades: > 95%. CAS No. 81409-74-7. Molecular formula: C18H20N2O2. Mole weight: 296.37.
Cabergoline Impurity B
European Pharmacopoeia (EP) Impurity B of Cabergoline. Alternative Names: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propenyl)-ergoline-1,8-dicarboxamide; Cabergoline EP Impurity B. Grades: > 95%. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.62.
Cabergoline Impurity D
A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum. Alternative Names: N-[3-(Dimethylamino)propyl]-6-(2-propen-1-yl)-(8β)-ergoline-8-carboxamide; (5R,8R,10R)-6-Allyl-N-[3-(dimethylamino)propyl]ergoline-8-carboxamide; FCE 21590. Grades: > 95%. CAS No. 85329-86-8. Molecular formula: C23H32N4O. Mole weight: 380.54.
Caboxine A
Caboxine A is isolated from the herbs of Catharanthus roseus. Alternative Names: 3-epi-Isocaboxine A; 3-epi-Vineridine; 7-epi-Caboxine B; Methyl (7α,19α,20α)-11-methoxy-19-methyl-2-oxoformosanan-16-carboxylate. Grades: 96%. CAS No. 53851-13-1. Molecular formula: C22H26N2O5. Mole weight: 398.5.
Cabozantinib
Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Grades: >98%. CAS No. 849217-68-1. Molecular formula: C28H24FN3O5. Mole weight: 501.51.
Cadion 2B
It can be used for the determination of silver in water. Alternative Names: 1-Triazene, 1-(4-nitro-1-naphthalenyl)-3-[4-(phenylazo)phenyl]-; 4-(4-Nitro-1-naphthyl-2-triazeno)azobenzene. Grades: ≥95%. CAS No. 6708-61-8. Molecular formula: C22H16N6O2. Mole weight: 396.41.
Caesalpine A
Caesalpine A is extracted from the seeds of Caesalpinia minax. CAS No. 1616757-59-5. Molecular formula: C23H32O7. Mole weight: 420.50.
Caesalpine B
Caesalpine B is extracted from the seeds of Caesalpinia minax. Alternative Names: Caesalpinin F1. CAS No. 1616757-60-8. Molecular formula: C23H30O7. Mole weight: 418.48.
Caftaric acid
Caftaric acid is a natural compound found in the juice of grapes. It is an inhibitor of the protein-protein interactions mediated by the Src-family kinases. Uses: Used in cancer therapy as an anticancer drug. Alternative Names: 2-Caffeoyl-L-tartaric acid; (2R,3R)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-3-hydroxybutanedioic acid. Grades: >98%. CAS No. 67879-58-7. Molecular formula: C13H12O9. Mole weight: 312.23.
Calanolide E
Calanolide E is a natural coumarin isolated from the barks of Calophyllum lanigerum. Alternative Names: 5-Hydroxy-6-(3-hydroxy-2-methylbutanoyl)-2,2-dimethyl-10-propyl-9 ,10-dihydro-2H,8H-pyrano[2,3-f]chromen-8-one. Grades: >98%. CAS No. 142566-61-8. Molecular formula: C22H28O6. Mole weight: 388.5.
Calcifediol Intermediate
A derivative of vitamin D3 and an intermediate of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Molecular formula: C33H56O3Si. Mole weight: 528.891.
Calcifediol Monohydrate EP Impurity A
Calcifediol Monohydrate EP Impurity A is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Alternative Names: Calcifediol EP Impurity A; 9β,10α-cholesta-5,7-diene-3β,25-diol; 25-Hydroxylumisterol; 25-Hydroxyprovitamin D3. CAS No. 61585-29-3. Molecular formula: C27H44O2. Mole weight: 400.65.
Calcipotriol EP Impurity F
An impurity of Calcipotriol, which is a ligand of VDR-like receptors. Alternative Names: (1α,3β,5Z,7E,22E,24S)-24-cyclopropyl-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-Secochola-5,7,10(19),22-tetraen-24-ol; (αS)-α-[(1E,3R)-3-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene. Grades: >98%. CAS No. 112875-61-3. Molecular formula: C39H68O3Si2. Mole weight: 641.13.
Calcipotriol EP Impurity H
Calcipotriol EP Impurity H, of which the strucure is composed of two calcipotriol molecules, is an impurity of Calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Alternative Names: (5Z,7E,22E,24R)-24-cyclopropyl-24-[[(5Z,7E,22E,24S)-24-cyclopropyl-1α,3β-dihydroxy-9,10-secochola-5,7,10(19),22-tetraen-24-yl]oxy]-9,10-secochola-5,7,10(19),22-tetraene-1α,3β-diol. Molecular formula: C54H78O5. Mole weight: 807.19.
Calcipotriol EP Impurity I
Calcipotriol EP Impurity I is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Alternative Names: (6S,7R,8R,22E,24S)-24-cyclopropyl-6,8:7,19-dicyclo-9,10-secochola-5(10),22-diene-1α,3β,24-triol; suprasterol of calcipotriol. Molecular formula: C27H40O3. Mole weight: 412.6.
Calcipotriol Impurity 1
(5E,24R)-Calcipotriene is an analog of (5E)-Calcipotriene ; the trans-isomeric impurity of Calcipotriene and a vitamin D3 analogue with antitumor effects. Alternative Names: (1α,3β,5E,7E,22E,24R)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol; (1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-5-Cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-. Grades: > 95%. CAS No. 112849-47-5. Molecular formula: C27H40O3. Mole weight: 412.62.
Calcipotriol Intermediate 9
Calcipotriol Intermediate 9 is an intermediate of calcipotriol synthesis. Calcipotriol is a vitamin D3 analogue used for psoriasis treatment. Alternative Names: (2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one; (5E)-1,3-Bis-O-(tert-Butyldimethylsilyl)-24-oxo-calcipotriene. CAS No. 112849-17-9. Molecular formula: C39H66O3Si2. Mole weight: 639.11.
Calcitonin human acetate
Calcitonin human acetate.
Calcitonin (human) (trifluoroacetate salt)
Calcitonin (human) (trifluoroacetate salt).
Calcitriol EP Impurity A
5,6-trans Calcitriol is an impurity of Calcitriol, which is the hormonally active form of vitamin D and is the active metabolite of vitamin D3. It is the trans isomer of Calcitriol. It is used as a control product to study calcitriol. Uses: Bone density conservation agents. Alternative Names: trans-Calcitriol; 5,6-trans-Calcitriol; 1,25-Dihydroxy-5,6-trans-vitamin D3; (5E,7E)-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol; (1α,3β,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-Dihydroxy-5,6-trans-vitamin D3. Grades: 98%. CAS No. 73837-24-8. Molecular formula: C27H44O3. Mole weight: 416.64.
Calcitriol EP Impurity B
Calcitriol EP Impurity B is the hormonally active form of vitamin D, and Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR), which inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. Alternative Names: Epi-Calcitriol; 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol; Impurity B of Calcitriol; 1β-Calcitriol; 1-epi-Calcitriol; (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1β,3β,25-triol. Grades: >98%. CAS No. 66791-71-7. Molecular formula: C27H44O3. Mole weight: 416.64.
Calcitriol EP Impurity C
Calcitriol EP Impurity C is an impurity of Calcitriol, which is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Alternative Names: Triazoline Adduct of pre-Calcitriol; pre-Calcitriol PTAD Adduct (Mixture of Diastereomers); Impurity C of Calcitriol (6aR,7R,9aR)-11-[(3S,5R)-3,5-dihydroxy-2-methylcyclohex-1-enyl]-7-[(1R)-5-hydroxy-1,5-dimethylhexyl]-6a-methyl-2-phenyl-5,6,6a,7,8,9,9a,11-octahydro-1H,4aH-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione. Grades: >98%. CAS No. 86307-44-0. Molecular formula: C35H49N3O5. Mole weight: 591.78.
Calcitriol Intermediate
A derivative of vitamin D3 and an intermediate of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Alternative Names: (5R)-ethyl-5-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-2-methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)hexanoate. CAS No. 169900-32-7. Molecular formula: C39H70O4Si2. Mole weight: 659.15.
Calcium Fructoborate
Calcium Fructoborate. CAS No. 250141-42-5.
Calcium Malate Granular
Calcium Malate Granular. CAS No. 17482-42-7.
Calebin A
Calebin A. CAS No. 336784-82-8.
Calenduloside E
Calenduloside E exhibits hypoglycemic activity by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush border of the small intestine in oral glucose-loaded rats. Alternative Names: Silphioside F; Glycoside St-E; Polysciasaponin P7; Momordin Ib; (4bS,5R,10bS,11R)-5,6,11,12-Tetrahydro-13,18-dimethyl-5,10b:11,4b-Bis(iminoethano)dibenzo[c,h][2,6]naphthyridine; (+)-Calycanthine; 5,6,11,12-tetrahydro-13,18-dimethyl-, [4bS-(4bα,5α,10bα,11α)]-5,10b:11,4b-Bis(iminoethano)dibenzo[c,h][2,6]naphthyridine; NSC 99016; [4bS-(4bα,5α,10bα,11α)]-5,6,11,12-Tetrahydro-13,18-dimethyl-5,10b:11,4b-bis(iminoethano)dibenzo[c,h][2,6]naphthyridine; d-Calycanthine. Grades: >98%. CAS No. 26020-14-4. Molecular formula: C36H56O9. Mole weight: 632.835.
Calindol hydrochloride
The calcium sensing receptor (CaSR) has a long amino terminal tail typical of family 3 of GPCRs including the metabotropic glutamate receptors, the c-aminobutyric acid B receptor and certain pheromone and taste receptors. Calindol hydrochloride is a new calcimimetic compound acting as (CaSR). It is a positive allosteric modulator of the human Ca2+ receptor which activates an extracellular ligand-binding domain-deleted, Rhodopsin-like, seven-transmembrane structure in the absence of Ca2+. Calindol is used to study the properties and distribution of CaSR in different types of cells and tissues. Alternative Names: Calindol. Grades: ≥98%. CAS No. 729610-18-8. Molecular formula: C21H20N2·HCl. Mole weight: 336.9.
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Alternative Names: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grades: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Calycanthoside
Calycanthoside is a coumarin found in Eleutherococcus senticosus that exhibits anti-inflammatory and antibacterial effects. Alternative Names: Isofraxidin 7-O-β-D-glucopyranoside; 6,8-Dimethoxy-7-(beta-D-glucopyranosyloxy)coumarin; 7-(beta-D-Glucopyranosyloxy)-6,8-dimethoxy-2H-1-benzopyran-2-one. Grades: 98.5%. CAS No. 483-91-0. Molecular formula: C17H20O10. Mole weight: 384.34.
Calyciphylline A
Calyciphylline A isolated from the branch of Daphniphyllum macropodum Miq. Alternative Names: Methyl (1R,2S,3R,5R,6S,8R,10S,16R,17R)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icos-13(19)-ene-17-carboxylate 8-oxide. Grades: 98.5%. CAS No. 596799-30-3. Molecular formula: C23H31NO4. Mole weight: 385.5.
Calyxamine B
Calyxamine B is a natural alkaloid found in the herbs of Salsola tetrandra. Alternative Names: 1-(2,2,6,6-Tetramethyl-4-piperidinylidene)acetone. Grades: >98%. CAS No. 150710-72-8. Molecular formula: C12H21NO. Mole weight: 195.3.