BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ciprofloxacin Impurity D HCl | An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Alternative Names: Ciprofloxacin Impurity D hydrochloride; USP Ciprofloxacin Related Compound A. Grades: > 95%. CAS No. 526204-10-4. Molecular formula: C17H19Cl2N3O3. Mole weight: 384.3. |  |
| Ciraparantag | Ciraparantag, also called as PER977, a synthetic, cationic small molecule, has potential to be a simple, inexpensive universal anticoagulation reversal agent. Alternative Names: PER-977; PER 977; PER977; Aripazine. CAS No. 1438492-26-2. Molecular formula: C22H48N12O2. Mole weight: 512.71. | |
| Cirsilineol | Cirsilineol is a trimethoxyflavone isolated from Artemisia and from Teucrium gnaphalodes. It selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Alternative Names: Fastigenin; Cirsileneol; Eupatrin; Anisomelin. Grades: 98%. CAS No. 41365-32-6. Molecular formula: C18H16O7. Mole weight: 344.32. | |
| Cirsiumaldehyde | Cirsiumaldehyde is found in TyphoniiRhizoma. Alternative Names: 5,5'-Oxybis(5-methylene-2-furaldehyde); O-Bisme-furaldehyde. Grades: > 95%. CAS No. 7389-38-0. Molecular formula: C12H10O5. Mole weight: 234.20. | |
| cis-2-Buten-1-ol | Cis-2-Buten-1-ol, a transparent, odorless liquid, finds applications in the production of various pharmaceuticals and serves as a valuable reagent in the realm of organic chemical synthesis. Promising therapeutic potentials have led to extensive investigation into the possibility of cis-2-Buten-1-ol's role in the management of sundry illnesses, including cancer. Alternative Names: (Z)-2-Buten-1-ol; 2-Buten-1-ol, (2Z)-; cis-2-Butenol; cis-2-Butenyl alcohol; cis-Crotyl Alcohol; Z-Crotyl alcohol. CAS No. 4088-60-2. Molecular formula: C4H8O. Mole weight: 72.11. | |
| cis-3-methoxycyclobutan-1-ol | Cis-3-methoxycyclobutan-1-ol, a synthetic organic compound utilized as a reagent in chemical synthesis, has exhibited promise as a pivotal intermediate in producing numerous bioactive molecules including anti-inflammatory, anti-tumor, and analgesic agents. Alternative Names: cis-3-Methoxycyclobutanol; Cyclobutanol, 3-methoxy-, cis-. CAS No. 1807941-46-3. Molecular formula: C5H10O2. Mole weight: 102.13. | |
| cis-3-Nonen-1-ol | Cis-3-Nonen-1-ol, an unsaturated alcohol, is a naturally occurring compound in grapes and various fruits. Its uses range from being a fragrance ingredient in perfumes to a flavoring agent in the food industry. Furthermore, studies reveal promising anti-inflammatory and analgesic properties that provide possibilities for therapeutic drugs in managing inflammation and pain-related diseases. Alternative Names: 3-Nonen-1-ol, (3Z)-; (Z)-3-nonen-1-ol. Grades: >95.0% by GC. CAS No. 10340-23-5. Molecular formula: C9H18O. Mole weight: 142.24. | |
| cis-4-Octenedioic acid | Cis-4-Octenedioic acid is a dicarboxylic fatty acid and a monounsaturated fatty acid. Alternative Names: 4-octenedioic acid; 4Z-octenedioic acid; (Z)-4-Octene-1,8-dioic acid. Grades: 95%. CAS No. 38561-68-1. Molecular formula: C8H12O4. Mole weight: 172.18. | |
| Cisapride | Cisapride is a drug that increases motility in the upper gastrointestinal tract and is used as a Gastroprokinetic. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. It is also a potent human ether-à-go-go-related gene (hERG) potassium channel inhibitor. It showed higher inhibitory effects on a hERG current with IC50 of 9.4 × 10-9 M in vitro. It inhibited Kv4.3 in a concentration-dependent manner with IC50 values of 9.8 uM. It could not bring about more colitis damages through 5HT(4) receptors. It was discovered by Janssen Pharmaceutica in 1980. It has been withdrawn from the market. Uses: Anti-ulcer agents; gastrointestinal agents; serotonin agonists. Alternative Names: Rel-Cisapride; R 51619; (±)-Cisapride. Grades: >99 %. CAS No. 81098-60-4. Molecular formula: C23H29ClFN3O4. Mole weight: 465.95. | |
| Cisatracurium Besilate | Cisatracurium besilate is a neuromuscular blocking agent that is used in liver transplant patient with safety. Cisatracurium besilate is also an enantiomer of Atracurium Besilate. Uses: Neuromuscular blocking agent. Alternative Names: (1R,1'R,2R,2'R)-2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium dibenzenesulfonate; Cisatracurium besylate. Grades: 99%. CAS No. 96946-42-8. Molecular formula: C65H82N2O18S2. Mole weight: 1243.487. | |
| cis-Dihydroquercetin | cis-Dihydroquercetin is a natural product found in Cryptocarya chinensis, Mangifera indica, and Camellia reticulata. cis-Dihydroquercetin is a derivative of Quercetin, which is a flavonoid with anticancer activity. Alternative Names: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3S)-; (2R-cis)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; (-)-Epitaxifolin; (2R,3S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; (2R,3S)-Epitaxifolin. CAS No. 114761-89-6. Molecular formula: C15H12O7. Mole weight: 304.25. | |
| cis-Miyabenol C | cis-Miyabenol C is a natural compound isolated from the herbs of Vitis vinifera. Alternative Names: Miyabenol C. Grades: 95.0%. CAS No. 168037-22-7. Molecular formula: C42H32O9. Mole weight: 680.709. | |
| Citral-[d6] | Citral-[d6] is an isotopic labelled Citral, a fragrance ingredient found in citrus fruit's peel oil. Alternative Names: Citral-d6. Molecular formula: C10H10D6O. Mole weight: 158.27. | |
| (-)-Citrinin-[13C,d2] | (-)-Citrinin-[13C,d2] is the labelled analogue of (-)-Citrinin, which is produced by the strain of Penicillum citrinum. Alternative Names: (-)-Citrinin-13C,D2; (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic Acid-13C,d2; (3R-trans)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic Acid-13C,d2; Citrinin-13C,d2; NSC 186-13C,d2. Grades: >95%. CAS No. 1329611-85-9. Molecular formula: C12[13C]H12D2O5. Mole weight: 253.25. | |
| Ciwujiatone | Ciwujiatone is purified from the herbs of Kalimeris integrifolia. Ciwujiatone shows significant activities against colon cancer cell lines SW480 and SW620. Alternative Names: (4-hydroxy-3,5-dimethoxyphenyl)-[(3R,4R,5S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methanone. Grades: 97.0%. CAS No. 218901-26-9. Molecular formula: C22H26O9. Mole weight: 434.44. | |
| CL2A-SN 38 | CL2A-SN 38 is a drug-linker conjugate for ADC by using SN 38 (a DNA Topoisomerase I inhibitor), linked via CL2A. Alternative Names: CL2A-SN-38. CAS No. 1279680-68-0. Molecular formula: C73H97N11O22. Mole weight: 1480.63. | |
| CL-387785 | CL-387785, also known as EKI-785, is an irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM). CL-387785 covalently bound to EGF-R. It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM), blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2, and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice (when given orally at 80 mg/kg/day for 10 days, daily). CL-387,785 is useful for studying the interaction of small molecules with EGF-R and may have clinical utility. Uses: Protein kinase inhibitors. Alternative Names: CL-387785; CL 387785; CL-387,785; CL387785; EKI-785; EKI 785; EKI785. Grades: 0.98. CAS No. 194423-06-8. Molecular formula: C18H13BrN4O. Mole weight: 381.233. | |
| CL 82,198 | CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It doesn't have effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is also used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis. Alternative Names: CL-82198; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide. Grades: ≥95%. CAS No. 307002-71-7. Molecular formula: C17H22N2O3. Mole weight: 302.4. | |
| Clarithromycin EP Impurity E | Clarithromycin EP Impurity E. CAS No. 81103-14-2. | |
| Clausine Z | Clausine Z comes from the herbs of Clausena excavata. Uses: Inhibitory activity on cdk5. Alternative Names: 1,6-Dihydroxy-9H-carbazole-3-carbaldehyde;3-formyl-1,6-dihydroxycarbazole. Grades: > 95%. CAS No. 866111-14-0. Molecular formula: C13H9NO3. Mole weight: 227.2. | |
| Clemizole hydrochloride | The hydrochloride salt form of clemizole, which is a histamine H1 antagonist with antitumor activity. It also has hepatitis C antiviral effect through restraining NS4B function and could also be used as an anticonvulsant in zebrafish Dravet syndrome model. Alternative Names: Allercur; Clemizole HCl; Clemizole (hydrochloride); Reactrol; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole hydrochloride. Grades: 95%. CAS No. 1163-36-6. Molecular formula: C19H20ClN3.HCl. Mole weight: 362.30. | |
| Cleomiscosin A | Cleomiscosin A is isolated from the herbs of Buxus sinica. Uses: Anti-inflammatory activity. Alternative Names: (2R,3R)-rel-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one. Grades: 97%. CAS No. 76948-72-6. Molecular formula: C20H18O8. Mole weight: 386.36. | |
| Cleomiscosin C | Cleomiscosin C is isolated from Buxus sinica, which can be beneficial in preventing LDL oxidation in atherosclerotic lesions. Uses: Anti-atherosclerotic. Alternative Names: (2R,3R)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one. Grades: >96%. CAS No. 84575-10-0. Molecular formula: C21H20O9. Mole weight: 416.4. | |
| Cleroindicin F | Cleroindicin F isolated from the herbs of Clerodendrum indicum. Alternative Names: (3aR,7aR)-3a-Hydroxy-3,3a,7,7a-tetrahydro-1-benzofuran-6(2H)-one. Grades: 0.95. CAS No. 189264-47-9. Molecular formula: C8H10O3. Mole weight: 154.2. | |
| Clevudine | Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active. Uses: Antiviral agents. Alternative Names: 1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; L FMAU; LFMAU; Levovir; 2'-Fluoro-5-methyl-b-L-arabinofuranosyluracil. Grades: ≥98% by HPLC. CAS No. 163252-36-6. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Clidinium bromide-[d5] | Clidinium-[d5] bromide is a labelled clidinium bromide. Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms. Alternative Names: Clidinium-D5 bromide; Clidinium-D5 (bromide). Molecular formula: C22H26BrNO3. Mole weight: 437.4. | |
| Clindamycin 3-Phosphate | Clindamycin 3-Phosphate is an impurity of Clindamycin, an antibiotic medication used for the treatment of bacterial infections. Alternative Names: Clindamycin phosphate EP Impurity C; methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-3-O-phosphono-1-thio-L-threo-α-D-galacto-octopyranoside. Grades: 90%. CAS No. 28708-34-1. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. | |
| Clindamycin 4-Phosphate | Clindamycin 4-Phosphate is an impurity of Clindamycin. Clindamycin is a widely evaluated drug and an important alternative antibiotic in the therapy of Staphylococcus aureus, especially in methicillin-resistant S. aureus (MRSA) infections. Alternative Names: Clindamycin phosphate EP Impurity D; Clindamycin 4-(dihydrogen phosphate); Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 4-(dihydrogen phosphate). Grades: 90%. CAS No. 54887-30-8. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. | |
| Clitorin | Clitorin is a natural compound utilized for the research of female sexual arousal disorder. Alternative Names: 2-(4-Hydroxyphenyl)-5,7-dihydroxy-3-[2-O,6-O-di(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3-[(2-O,6-O-di-α-L-rhamnopyranosyl-β-D-glucopyranosyl)oxy]flavone; Kaempferol 3-O-(2,6-α-L-dirhamnopyranosyl-β-D-glucopyranoside); Kaempferol 3-(2G-rhamnosylrutinoside); 3-[(O-6-Deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 55804-74-5. Molecular formula: C33H40O19. Mole weight: 740.66. | |
| Clobetasol Propionate EP Impurity J | An impurity of Clobetasol propionate. Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Alternative Names: (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2'-furan]-3,3'-dione (17α-spiro compound); 9α-Fluoro-11β-hydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one]; (2'R,8S,9R,10S,11S,13S,14S,16S)-4'-Chloro-5'-ethyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,3'(6H)-dione; Clobetasol Propionate USP Related Compound A; 9α-Fluoro-11β-hydroxy-16β-methyl 3-oxo-androsta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one]; Clobetasol Propionate Related Compound A; USP Clobetasol Propionate Related Compound A; (17R)-4'-Chloro-5'-ethyl-9-fluoro-11beta-hydroxy-16beta-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione. Grades: ≥95%. CAS No. 1486466-31-2. Molecular formula: C25H30ClFO4. Mole weight: 448.95. | |
| Clocortolone Pivalate | Clocortolone Pivalate is a Corticosteroid Hormone Receptor Agonist. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom. Uses: Clocortolone pivalate is a corticosteroid hormone receptor agonist. Alternative Names: 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate, Clocortolone 21-pivalate; (6α,11β,16α)-9-Chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methypregna-1,4-diene-3,20-dione; CL 68; Clocortolone trimethylacetat. Grades: > 95%. CAS No. 34097-16-0. Molecular formula: C27H36ClFO5. Mole weight: 495.04. | |
| Clonidine Hydrochloride EP Impurity B | Clonidine Hydrochloride EP Impurity B. CAS No. 54707-71-0. | |
| Clopidogrel EP Impurity A | An impurity of Clopidogrel, an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Alternative Names: Clopidogrel carboxylic acid; USP Clopidogrel Related Compound A; Clopidogrel USP Related Compound A; Clopidogrel Related Compound A; (+)-(S)-(o-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid; (2S)-2-(2-chlorophenyl)-2-[6,7-dihydrothieno[3,2-c]-pyridin-5(4H)-yl]acetic acid; Clopidogrel Impurity A; Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, (αS)-; (αS)-α-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid; (S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid; SR 26334. Grades: ≥95%. CAS No. 144457-28-3. Molecular formula: C15H14ClNO2S. Mole weight: 307.80. | |
| Clopidogrel Impurity D | Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester is an impurity of Clopidogrel, an antithrombotic agent. Alternative Names: Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester. Grades: > 95%. CAS No. 1421283-60-4. Molecular formula: C24H21Cl2NO4S. Mole weight: 490.4. | |
| Clopidogrel Impurity K | An impurity of Clopidogrel, an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Alternative Names: (+/-)-RAC-2-(2-CHLOROPHENYL)-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)ACETONITRILE. CAS No. 444728-11-4. Molecular formula: C15H13ClN2S. Mole weight: 288.8. | |
| Clopidogrel Related Compound B | Clopidogrel Related Compound B is a tetrahydrothienopyridine as inhibitor of angiogenesis. Alternative Names: Methyl (+/-)-(o-Chlorophenyl)-4,5-dihydrothieno[3,2-c]pyridine-6(7H)acetate Hydrochloride; α-(2-Chlorophenyl)-4,7-dihydro-thieno[2,3-c]pyridine-6(5H)acetic Acid Methyl Ester Hydrochloride. Grades: > 95%. CAS No. 144750-52-7. Molecular formula: C16H17Cl2NO2S. Mole weight: 358.28. | |
| Clopidogrel USP Related Compound C | An impurity of Clopidogrel, an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Alternative Names: USP Clopidogrel Related Compound C; Methyl (-)-(R)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, hydrogen sulfate; Clopidogrel Bisulfate Related Compound C; Clopidogrel RC C; Clopidogrel Related Compound C; Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αR)-, sulfate (1:1); (R)-(-)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate; (R)-(-)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate; (R)-Clopidogrel bisulfate; (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate; SR 25989C; R-(-)-Clopidogrel Hydrogen Sulfate. Grades: ≥95%. CAS No. 120202-71-3. Molecular formula: C16H16ClNO2S.H2O4S. Mole weight: 419.90. | |
| Cloprostenol sodium | Cloprostenol sodium is a synthetic and water-soluble aryl-oxymethyl analog of prostaglandin F2α. lt is also a potent inhibitor of rat adipose precursor differentiation in primary cultures. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also used for the treatment of infertility in sows and gilts. Uses: Luteolytic agents. Alternative Names: ICI 80996; ICI-80996; ICI 80996; ICI 80,996; ICI-80,996; ICI 80,996; DL-Cloprostenol sodium; Estroplan; Estrumate;DL-Cloprostenol sodium;Estroplan;Estrumate;sodium (Z)-7-(2-((E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;5-Heptenoicacid,7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-. Grades: >98%. CAS No. 55028-72-3. Molecular formula: C22H28ClNaO6. Mole weight: 446.9. | |
| (+)-Cloprostenol sodium salt | (+)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol, which is an aryl-oxymethyl analog of prostaglandin F2α. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also an FP receptor agonist. Uses: Luteolytic agents. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt; [1R-[1α(Z),2β(1E,3R*),3α,5α]]- 7-[2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt. Grades: 98%. CAS No. 62561-03-9. Molecular formula: C22H28ClO6Na. Mole weight: 446.90. | |
| Cnidilin | Cnidilin is a compound of the coumarin class found in the roots of Angelica dahurica. Cnidilin has the potential for the treatment of CNS diseases for its BBB permeability. Alternative Names: Kinidilin; Isophellopterin; 9-methoxy-4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one. Grades: >98%. CAS No. 14348-22-2. Molecular formula: C17H16O5. Mole weight: 300.31. | |
| CNX-2006 | CNX-2006 is a potent and mutant-selective EGFR inhibitor with excellent in vitro activity in cells with activating EGFR mutations, as well as in cells harbouring the T790M mutation. CNX-2006 is the prototype for CO-1686, which is currently in a Phase I clinical trial for the treatment of EGFR-mutant lung cancer. Alternative Names: CNX2006; CNX 2006; N-[3-[[2-[4-[[1-(2-fluoroethyl)azetidin-3-yl]amino]-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide. Grades: 98%. CAS No. 1375465-09-0. Molecular formula: C26H27F4N7O2. Mole weight: 545.543. | |
| Cobalt(III) acetylacetonate | Cobalt(III) acetylacetonate is used as a polymerization catalyst, vulcanizing agent, pigment in resins and glass. Alternative Names: Co(acac)3; Cobalt(III) 2,4-pentanedionate. Grades: 98%. CAS No. 21679-46-9. Molecular formula: C15H21CoO6. Mole weight: 356.26. | |
| Coccinic acid | Coccinic acid isolated from the roots of Kadsura coccinea. Alternative Names: 3-(Benzoyloxy)-2-(Methoxycarbonyl)-8-azabicyclo[3.2.1]octane-8-carboxylic acid;Lanosta-9(11),24-dien-26-oic acid, 3-oxo-, (24E)-. Grades: > 95%. CAS No. 107783-45-9. Molecular formula: C30H46O3. Mole weight: 454.7. | |
| Coelenterazine 400a | Coelenterazine 400a is a derivative of coelenterazine that produces chemiluminescence displayed by the Aequorin protein in the presence of Ca2+. It is used in BRET study as an indicator for intracelluar Ca2+. Alternative Names: 6-phenyl-2,8-bis(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one; BlueSyn C. Grades: ≥95%. CAS No. 70217-82-2. Molecular formula: C26H21N3O. Mole weight: 391.5. | |
| COF-300 | COF-300. CAS No. 1133843-97-6. | |
| Columbianetin | Columbianetin is isolated from Radix Angelicae Pubescentis. Columbianetin inhibited the histamine release by substance P. It may be helpful in regulating mast cell-mediated allergic inflammatory responses. Uses: Inhibition of platelet aggregation, inhibition of fungus. Alternative Names: 2H-Furo(2,3-h)-1-benzopyran-2-one, 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-, (S)-. Grades: >98%. CAS No. 3804-70-4. Molecular formula: C14H14O4. Mole weight: 246.26. | |
| Columbianetin acetate | Columbianetin acetate is a coumarin with anti-fungal and anti-inflammatory activity. Alternative Names: (+)-Columbianetin acetate; (S)-Columbianetin acetate; O-Acetylcolumbianetin. Grades: 0.98. CAS No. 23180-65-6. Molecular formula: C16H16O5. Mole weight: 288.3. | |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Alternative Names: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. Grades: >98%. CAS No. 135463-81-9. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
| Complanatuside A | Complanatuside A, a flavonoid compound, is isolated from Astragalus complanatus and Lysimachia christinae. Astragalus complanatus R.Brown is a widely used herbal material in traditional Chinese medicine. The total flavonoid (TF) is an active fraction extracted from seeds of Astragalus complanatus R.Brown. Previous studies performed in animals have demonstrated the antihypertensive efficacy of the TF. Alternative Names: Complanatuside; 3-(beta-D-Glucopyranosyloxy)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one. Grades: > 98%. CAS No. 116183-66-5. Molecular formula: C28H32O16. Mole weight: 624.54. | |
| Conopharyngine | Conopharyngine is isolated from the herbs of Voacanga africana. Alternative Names: 12,13-Dimethoxyibogamine-18-carboxylic acid methyl ester. Grades: 96.5%. CAS No. 76-98-2. Molecular formula: C23H30N2O4. Mole weight: 398.5. | |
| Conquinamine | Conquinamine is a natural alkaloid isolated from Cinchona ledgeriana. . Alternative Names: Epiquinamine,3-epi-Quinamine. Grades: >98%. CAS No. 464-86-8. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| Continentalic acid | Continentalic acid is found in the roots of Aralia continentalis. Alternative Names: Pimaradienoic acid; Pimara-8(14),15-diene-19-oic acid. Grades: > 95%. CAS No. 19889-23-7. Molecular formula: C20H30O2. Mole weight: 302.45. | |
| Copanlisib | Copanlisib is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. BAY 80-6946 inhibits the activation of the PI3K signaling pathway, which may result in the inhibition of tumor cell growth and survival in susceptible tumor cell populations. Alternative Names: BAY 80-6946; Aliqopa; BAY-80-6946; 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide. Grades: ≥98%. CAS No. 1032568-63-0. Molecular formula: C23H28N8O4. Mole weight: 480.529. | |
| Coptisine Sulfate | Coptisine Sulfate is an alkaloid isolated from Chinese goldthread. It exhibits growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. Uses: Anticancer. Alternative Names: 6,7-Dihydro-bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium sulfate; Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium, 6,7-dihydro-, sulfate (1:1). Grades: >98%. CAS No. 1198398-71-8. Molecular formula: C19H15NO8S. Mole weight: 417.4. | |
| (±)-Corey lactone diol | (±)-Corey lactone diol is an impurity of lubiprostone, a bicyclic fatty acid metabolite analog of Prostaglandin E1. Alternative Names: (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. Grades: >95%. CAS No. 54423-47-1. Molecular formula: C8H12O4. Mole weight: 172.18. | |
| Coriatin | Coriatin is a natural sesquiterpenoid isolated from the herbs of Coriaria nepalensis Wall. Alternative Names: (2R,3S,5R,6R,7R)-2-Hydroxy-12-(2-hydroxy-2-propanyl)-7-methyl-11H-spiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxiran]-11-one. Grades: >98%. CAS No. 91653-75-7. Molecular formula: C15H20O6. Mole weight: 296.3. | |
| (-)-CorluMine | (-)-Corlumine is a natural alkaloid compound found in some plant. Alternative Names: (S)-6-((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one. Grades: >98%. CAS No. 79082-64-7. Molecular formula: C21H21NO6. Mole weight: 383.39. | |
| CORM-3 | CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Alternative Names: Tricarbonylchloro(glycinato)ruthenium; (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium; CORM3; CORM 3. Grades: >98%. CAS No. 475473-26-8. Molecular formula: C5H4ClNO5Ru. Mole weight: 294.61. | |
| Cornoside | Cornoside is a natural compound isolated from the leaves of Abeliophyllum distichum, and it is one of the chemosystematic markers. Alternative Names: 4-hydroxy-4-[2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]cyclohexa-2,5-dien-1-one. Grades: 96.5%. CAS No. 40661-45-8. Molecular formula: C14H20O8. Mole weight: 316.306. | |
| Coronarin A | Coronarin A, a natural diterpenoid isolated from the rhizomes of Hedychium coronarium, exhibits good growth inhibition activities on HUVEC proliferation. At the concentration of 10 micro g/mL, coronarin A and epi-coronarin A especially suppressed the growth factor induced tube formation of HUVEC. Uses: Inhibit growth of huvec. Alternative Names: (2S,4R,4aS,8aS)-4-[(E)-2-(3-Furyl)vinyl]-4a,8,8-trimethyl-3-methy lenedecahydro-2-naphthalenol. Grades: >98%. CAS No. 119188-33-9. Molecular formula: C20H28O2. Mole weight: 300.4. | |
| Coronarin B | Coronarin B, also called 3H-1,2-Dioxepin-5-carboxaldehyde, 7-(decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)-4,7-dihydro-3-hydroxy-, is a natural diterpenoid isolated from the rhizomes of Hedychium coronarium. Coronarin B has cytotoxic and antiplasmodial activities. Uses: Anti-plasmodial. Alternative Names: 3H-1,2-Dioxepin-5-carboxaldehyde, 7-(decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)-4,7-dihydro-3-hydroxy-. Grades: >96%. CAS No. 119188-38-4. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| Coronarin D | Coronarin D, a natural labdane-type diterpene found in the rhizomes of Hedychium coronarium,inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis. Coronarin D exhibits promising antifungal activity against C. Uses: Antif-ungal. Alternative Names: 15-Hydroxy-8(17),12-labdadien-16,15-olide. Grades: >97%. CAS No. 119188-37-3. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| Coronarin D ethyl ether | Coronarin D ethyl ether is a natural diterpenoid found in the rhizomes of Hedychium coronarium, it leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis by inhibiting NF-KB activation pathway. And vitro, coronarin D shows promising antifungal activity against C. albicans. Uses: Antifungal. Alternative Names: (3E)-5-Ethoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedeca hydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone. Grades: >98%. CAS No. 138965-89-6. Molecular formula: C22H34O3. Mole weight: 346.5. | |
| Coronarin E | Coronarin E, a natural diterpenoid found in the rhizomes of Hedychium coronarium,exhibits the activity of antiplasmodial. Uses: Anti-plasmodial. Alternative Names: 15,16-Epoxy-8(17),11,13(16),14-labdatetraene. Grades: >98%. CAS No. 117591-81-8. Molecular formula: C20H28O. Mole weight: 284.4. | |
| Corosolic acid | Corosolic acid, that is isolated from the barks of Lagerstroemia speciosa, contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts its anticancer activity against colon cancer cells by promoting the N-terminal phosphorylation and subsequent proteasomal degradation of β-catenin. Besides, Corosolic acid induced apoptosis in colorectal cancer (CRC), rendering this compound a potential anticancer agent for the treatment of CRC. Corosolic acid, as a new plant medicine for preventing and treating obesity and type II diabetes, and a functional natural health food and pharmaceutical raw material, has become a popular product in the market. Uses: Anti-angiogenic / anticancer. Alternative Names: 2-A-HYDROXYURSOLIC ACID; 2ALPHA-HYDROXYURSOLIC ACID; 2,3-DIHYDROXYURS-12-EN-28-OIC ACID; HYDROXYURSOLIC ACID; COROSOLIC ACID; Corsolicacid; Corosolic; (2a,3b)-2,3-Dihydroxy-urs-12-en-28-oic acid. Grades: >98%. CAS No. 4547-24-4. Molecular formula: C30H48O4. Mole weight: 472.7. | |
| Corydalmine | Corydalmine,an natural plant alkaloid isolated from roots of Corydalis chaerophylla, can inhibit spore germination of some plant pathogenic as well as saprophytic fungi e.g. Alternaria brassicae, A. brassicicola, A. solani, Curvularia lunata, C. maculans, C. sp., C. pallscens, Erysiphe pisi, Fusarium udum, Helminthosporium species,H. penniseti and a Heterosporium species; it can significantly inhibit spore germination of all the fungi at 100 to 1500 ppm, it is effective against all the fungi at 1500 ppm. C. l-Corydalmine exhibits activity of potent analgesic in preclinical models, it is under development as an oral analgesic agent. Uses: Anti-bacterial. Alternative Names: (-)-Kikemanine;(13aS)-5,8,13,13a-Tetrahydro-2,3,9-trimethoxy-6H-dibenzo[a, g]quinolizin-10-ol;Kikemanin;Kikemanine;Schefferine. Grades: >95%. CAS No. 30413-84-4. Molecular formula: C20H23NO4. Mole weight: 341.4. | |
| Corylifol C | Corylifol C isolated from the seeds of Psoralea corylifolia L. Alternative Names: 2-(3,4-Dihydroxyphenyl)-7-hydroxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: 0.95. CAS No. 775351-91-2. Molecular formula: C20H18O5. Mole weight: 338.4. | |
| Corylin | Corylin is a major bioactive compound isolated from Psoralea corylifolia L. It is antibiotic or anticancer compound. Uses: Anti-biotic; anti-cancer. Alternative Names: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Grades: >98%. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34. | |
| Corynoline | Corynoline, which is found in the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor. Uses: Sedative / anti-leptospira. Alternative Names: Corynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-, dimethyl-, (5bR,6S,12bR)-; (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol; 13-Methylchelidonan-11β-ol. Grades: >98%. CAS No. 18797-79-0. Molecular formula: C21H21NO5. Mole weight: 367.4. | |
| Corynoxeine | Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and a useful and prospective compound in the prevention and treatment for vascular diseases. Uses: Antihypertension. Alternative Names: corynoxeine; (7R,16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; (alphaE,1'R,6'R,7'S,8'aS)-6'-Ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester; 16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-aceticacid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-, methyl ester, (aE,1'R,6'R,7'S,8'aS)-. Grades: >98%. CAS No. 630-94-4. Molecular formula: C22H26N2O4. Mole weight: 382.45. | |
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