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Deacetyl ganoderic acid F
Deacetyl ganoderic acid F, a natural triterpenoid compound obtained from the Ganoderma lucidum, displays an array spectrum of pharmacological activities, particularly antitumor, immunomodulatory, and antiviral properties, to name a few. Moreover, Deacetyl ganoderic acid F exhibits effective outcomes for treating liver-associated diseases, for instance, hepatic fibrosis, liver cancer, and hepatitis, thereby, promising a potential therapeutic agent for liver dysfunctions. Alternative Names: Deacetyl ganoderic acid F; Ganoderic acid F, deacetyl-; (12beta)-12-Hydroxy-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid. Grades: >98%. CAS No. 100665-44-9. Molecular formula: C30H40O8. Mole weight: 528.6.
Deacetylpseudolaric acid A
Deacetylpseudolaric acid A isolated from the root bark of Pseudolarix amabilis. Alternative Names: (2E,4E)-5-[(1R,7S,8R,9R)-7-Hydroxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methyl-2,4-pentadienoic acid. Grades: 0.985. CAS No. 82508-37-0. Molecular formula: C20H26O5. Mole weight: 346.4.
Deacetylpseudolaric acid C2
Deacetylpseudolaric acid C2 isolated from the root bark of Pseudolarix amabilis. Uses: Demethoxydeacetoxypseudolaric acid b. Alternative Names: (1R,7S,8R,9R)-9-[(1E,3E)-4-Carboxy-1,3-pentadien-1-yl]-7-hydroxy-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid. Grades: 0.98. CAS No. 82508-36-9. Molecular formula: C20H24O7. Mole weight: 376.4.
Deacetylxylopic acid
Deacetylxylopic acid is isolated from the herbs of Nouelia insignis. Alternative Names: (5β,8α,9β,10α,13α,15β)-15-Hydroxykaur-16-en-18-oic acid. Grades: 98.5%. CAS No. 6619-95-0. Molecular formula: C20H30O3. Mole weight: 318.5.
Decahydrodecaborate ammonium salt
Decahydrodecaborate ammonium salt. CAS No. 12008-61-6.
Decamethoxine
Decamethoxine, a cationic gemini surfactant, has strong bactericidal and fungicidal effects, and changes the permeability of microbial cell membranes, resulting in the destruction and death of a variety of microorganisms. Uses: Anti-infective agents, local. Alternative Names: Septefril; Decametoxin; Dekametoksin; Decamethoxin; 1,10-Decanediaminium, N1,N1,N10,N10-tetramethyl-N1,N10-bis[2-[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-, chloride (1:2); Decamethoxinum; Decamethylene-1,10-bis(dimethylcarbomenthoxymethylammonium) dichloride; MM 692; 1,10-Decanediaminium, N,N,N',N'-tetramethyl-N,N'-bis[2-[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-, dichloride; N1,N10-bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride. Grades: ≥95%. CAS No. 38146-42-8. Molecular formula: C38H74Cl2N2O4. Mole weight: 693.91.
Decarine
Decarine isolated from the roots of Zanthoxylum nitidum. It has low cytotoxicity towards human macrophages. Uses: Antibacterial activity. Alternative Names: 1-methoxy-[1,3]benzodioxolo[5,6-c]phenanthridin-2-ol. Grades: 97.5%. CAS No. 54354-62-0. Molecular formula: C19H13NO4. Mole weight: 319.3.
Decinnamoyltaxagifine
Decinnamoyltaxagifine is extracted from the barks of Taxus chinensis var. mairei. Grades: 97.5%. CAS No. 130394-69-3. Molecular formula: C28H38O12. Mole weight: 566.60.
Decursinol
Decursinol is a coumarin isolated from Angelica gigas. It shows anti-tumor and anti-metastasis activity. Alternative Names: (+)-Decursinol. Grades: 98%. CAS No. 23458-02-8. Molecular formula: C14H14O4. Mole weight: 246.26.
Defactinib
Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor PF-04554878 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK / MAPK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation and survival. The tyrosine kinase FAK is , a signal transducer for integrins that is upregulated in many tumor cell types and is involved in tumor cell invasion, migration and proliferation. Alternative Names: N-methyl-4-((4-(((3-(N-methylmethylsulfonamido)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878. Grades: >98%. CAS No. 1073154-85-4. Molecular formula: C20H21F3N8O3S. Mole weight: 510.496.
Deferasirox
Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Alternative Names: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid; Exjade; ICL-670; ICL-670A; CGP-72670. Grades: >98%. CAS No. 201530-41-8. Molecular formula: C21H15N3O4. Mole weight: 373.36.
Defluoro Aprepitant
A metabolite of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Alternative Names: Desfluoro aprepitant; Aprepitant Impurity A; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant EP Impurity A; 5-([(2R,3S)-2-((R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy)-3-phenylmorpholino]methyl)-1H-1,2,4-triazol-3(2H)-one; Aprepitant desfluoro; 5-[[(2R,3S)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholino]methyl]-2H-1,2,4-triazol-3(4H)-one. Grades: >95%. CAS No. 170729-76-7. Molecular formula: C23H22F6N4O3. Mole weight: 516.45.
Defluoro Levofloxacin
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Alternative Names: (3S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Levofloxacin Related Compound F (USP). Grades: > 95%. CAS No. 117620-85-6. Molecular formula: C18H21N3O4. Mole weight: 343.39.
Defluoro Linezolid
Defluoro Linezolid is an impurity of Linezolid, which is an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Alternative Names: (S)-N-{[3-(4-Morpholinophenyl)-2-oxooxazolidin-5-yl]methyl}acetamide; Desfluoro linezolid; N-[[(5S)-3-[4-(4-Morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5S)-3-[4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Desfluorolinezolid; 1-({[(5S)-3-(p-Morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}amino)-1-ethanone. Grades: ≥95%. CAS No. 556801-15-1. Molecular formula: C16H21N3O4. Mole weight: 319.36.
Dehydroacerogenin C
Dehydroacerogenin C is a natural compound with anti-cancer prowess aiding in the research of breast and lung malignancies. Alternative Names: Dehydroacerogenin C; AKOS040762848; 152041-27-5. Grades: 98.0%. CAS No. 152041-27-5. Molecular formula: C19H18O3. Mole weight: 294.35.
Dehydro Aripiprazole-[piperazine-d8] Hydrochloride, is the labelled analogue of Dehydro Aripiprazole, which is a metabolite of Aripiprazole. Aripiprazole is an atypical antipsychotic indicated for schizophrenia and bipolar disorder. Alternative Names: Dehydro Aripiprazole-d8 Hydrochloride. Grades: 97% (CP); 98% atom D. CAS No. 1215383-78-0. Molecular formula: C23H18D8Cl3N3O2. Mole weight: 490.88.
Dehydrobruceantin
Dehydrobruceantin is extracted from the seeds of Brucea javanica (L.) Merr. It shows anti-tuberculosis activity. Alternative Names: 15β-[[(E)-3,4-Dimethyl-1-oxo-2-pentenyl]oxy]-13,20-epoxy-2,11β,12α-trihydroxy-3,16-dioxopicrasa-1,4-dien-21-oic acid methyl ester. Grades: 98.0%. CAS No. 53662-98-9. Molecular formula: C28H34O11. Mole weight: 546.56.
Dehydrobruceantinol
Dehydrobruceantinol is extracted from the seeds of Brucea javanica (L.) Merr. It tastes bitter and shows antileukemic activity. Alternative Names: Dehydrobruceantinol; 99132-99-7; (+)-Dehydrobruceantinol; NSC330518; AKOS040761589; NSC-330518; HY-135421; CS-0112731; methyl (1R,2S,3R,6R,13S,14R,15R,16S,17S)-3-[(E)-4-acetyloxy-3,4-dimethylpent-2-enoyl]oxy-11,15,16-trihydroxy-9,13-dimethyl-4,10-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadeca-8,11-diene-17-carboxylate; Picrasa-1, 15-[[4-(acetyloxy)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-13,20-epoxy-/2,11,12-trihydroxy-3,16-dioxo-, methyl ester, [11.beta.,12.alpha.,15.beta.(E)]-. Grades: 98.0%. CAS No. 99132-99-7. Molecular formula: C30H36O13. Mole weight: 604.59.
Dehydrocholic acid-[2,2,4,4-d4]
Dehydrocholic acid-[2,2,4,4-d4] is the labelled analogue of dehydrocholic acid, which is a derivative of Cholic Acid and manufactured by the oxidation of cholic acid. Grades: ≥95%. Molecular formula: C24H30D4O5. Mole weight: 406.56.
Dehydrocrenatidine
Dehydrocrenatidine isolated from the barks of Picrasma quassioides. It can inhibit JAK-STAT3-dependent DU145 and MDA-MB-468 cell survival and induce cell apoptosis. Uses: It is a jak-specific inhibitor. Alternative Names: 1-ethenyl-4,8-dimethoxy-9H-pyrido[3,4-b]indole. Grades: 0.98. CAS No. 65236-62-6. Molecular formula: C15H14N2O2. Mole weight: 254.3.
Dehydrodeguelin
Dehydrodeguelin is a natural flavonoid found in the herbs of Derris robusta. Alternative Names: 6a,12a-Dehydrodeguelin;9,10-Dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(13H)-one. Grades: >97%. CAS No. 3466-23-7. Molecular formula: C23H20O6. Mole weight: 392.4.
Dehydroeburicoic acid
Eburicoic acid and Dehydroeburicoic acid protect the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. Alternative Names: 3β-Hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid 3β-Hydroxy-24-methylenelanosta-7,9(11)-diene-21-oic acid. Grades: >98%. CAS No. 6879-5-6. Molecular formula: C31H48O3.
Dehydroeffusol
Dehydroeffusol is found in the Juncus effusus L. Dehydro Effusol has the potential to treat gastric cancer for its inhibitory effect on gastric cancer cell growth. Alternative Names: 5-Ethenyl-1-methylphenanthrene-2,7-diol. Grades: >98%. CAS No. 137319-34-7. Molecular formula: C17H14O2. Mole weight: 250.297.
Dehydro Ivabradine Oxalate
Dehydro Ivabradine Oxalate is a potent pharmaceutical compound used in the research of cardiovascular diseases, specifically targeting heart failure and chronic stable angina. This compound acts as a selective inhibitor of the If current in sinoatrial node cells. Alternative Names: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one; compound with oxalic acid. Grades: > 95%. CAS No. 1346558-08-4. Molecular formula: C29H36N2O9. Mole weight: 556.62.
Dehydroperilloxin
Dehydroperilloxin is a natural compound isolated from the stems of Perilla frutescens var. acuta. Alternative Names: 2-(5-methoxyfuro[3,2-i][3]benzoxepin-2-yl)propan-2-ol. Grades: 95.0%. CAS No. 263241-09-4. Molecular formula: C16H16O4. Mole weight: 272.3.
Dehydrotoxicarol
Dehydrotoxicarol is a flavonoid derivative isolated from the herbs of Derris trifoliata Lour. Alternative Names: 7a,13a-Didehydrotoxicarol. Grades: 98%. CAS No. 59086-93-0. Molecular formula: C23H20O7. Mole weight: 408.4.
DEL-22379
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ?0.5 μM. Alternative Names: DEL-22379; DEL 22379; DEL22379. Grades: 98%. CAS No. 181223-80-3. Molecular formula: C26H28N4O3. Mole weight: 444.53.
Delavinone
Delavinone is an alkaloid isolated from the bulbs of Fritillaria yuminensis. Alternative Names: Puqiedinone; Sinpeinine A; 3-Hydroxycevan-6-one. Grades: >98%. CAS No. 96997-98-7. Molecular formula: C27H43NO2. Mole weight: 413.646.
Delavirdine mesylate
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1. Uses: Anti-hiv agents. Alternative Names: Delavirdine mesylate; Rescriptor; U-90152S; U 90152S; U90152S; U 90152T U-90152T; U90152T; U 90152E; U-90152E; U90152E. Grades: >98%. CAS No. 147221-93-0. Molecular formula: C23H32N6O6S2. Mole weight: 552.67.
Delbonine
Delbonine is a norditerpenoid alkaloid isolated from the roots of Delphinium stapeliosum. Alternative Names: 14-O-Acetyldeltatsine; Aconitane-1,7,14-triol, 20-ethyl-6,8,16-trimethoxy-4-(methoxymethyl)-,14-acetate, (1alpha,6beta,14alpha,16beta)-. Grades: 97.0%. CAS No. 95066-33-4. Molecular formula: C27H43NO8. Mole weight: 509.64.
Delgocitinib
Delgocitinib. CAS No. 1263774-59-9.
Delgrandine
Delgrandine is an alkaloid isolated from Delphinium davidii. Alternative Names: Delgradine. Grades: 98.0%. CAS No. 145237-05-4. Molecular formula: C41H43NO12. Mole weight: 741.79.
Delpazolid
Delpazolid is an oxazolidinone antibiotic. It is active against a wide range of Gram-positive bacterial clinical isolates, including resistant strains of several species. Delpazolid increases survival in mouse models of systemic MRSA, E. faecalis, S. pneumoniae, and H. influenzae infection. Alternative Names: LCB01-0371; LCB-01-0371; LCB-010371. Grades: ≥98%. CAS No. 1219707-39-7. Molecular formula: C14H17FN4O3. Mole weight: 308.31.
Delphinidin 3-glucoside
Delphinidin 3-glucoside is a derivative of anthocyanidin, a primary plant pigment and antioxidant. Alternative Names: Delphinidin 3-O-glucoside; Delphinidin 3-O-glucoside cation; Delphinidin 3-O-beta-D-glucoside. CAS No. 50986-17-9. Molecular formula: C21H21O12+. Mole weight: 465.4.
Delsoline
Delsoline is a hypotensive alkaloid isolated from Aconitum. Alternative Names: 20-Ethyl-6β,14α,16β-trimethoxy-4-(methoxymethyl)aconitane-1α,7,8-triol; Belsoline; 14-O-Methyldelcosine; 18-O-Methylgigactonine; Acomonine. Grades: 97 % (TLC). CAS No. 509-18-2. Molecular formula: C25H41NO7. Mole weight: 467.60.
Δ2-Cefepime
An impurity of Cefepime, a cephalosporin antibiotic against Gram-positive and Gram-negative bacteria. Alternative Names: Pyrrolidinium, 1- [[(6R, 7R) - 7- [[(2Z) - 2- (2- amino- 4- thiazolyl) - 2- (methoxyimino) acetyl] amino] - 2- carboxy- 8- oxo- 5- thia- 1- azabicyclo[4.2.0] oct- 3- en- 3- yl] methyl] - 1- methyl- , inner salt; Delta2-Cefepime. Grades: > 95%. CAS No. 88040-25-9. Molecular formula: C19H24N6O5S2. Mole weight: 480.57.
Deltaline
Deltaline has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair conformations with the fourth adopting a boat conformation while all of the five-membered rings exhibit envelope conformations. Intermolecular O-H center dot O hydrogen bonding is present in the crystal structure. Alternative Names: 1α,14α,16β-Trimethoxy-4-methyl-7β,8-(methylenedioxy)-20-ethylaconitane-6β,10-diol 6-acetate; 20-Ethyl-1α,14α,16β-trimethoxy-4-methyl-7,8-[methylenebis(oxy)]aconitane-6β,10-diol 6-acetate; (1alpha,6alpha,14alpha,16beta)-20-Ethyl-1,14,16-trimethoxy-4-methyl-7,8-[methylenebis(oxy)]aconitane-6,10-diol 6-acetate; Delphelatine; Deltamine 6-acetate; Eldeline. Grades: 97 % (TLC). CAS No. 6836-11-9. Molecular formula: C27H41NO8. Mole weight: 507.62.
Deltatsine
Deltatsine is an alkaloid isolated from Delphinium stapeliosum. Alternative Names: Deltatsine; 92631-66-8; 11-ethyl-6,8,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,9,16-triolDTXSID7091903920-ethyl-6,8,16-trimethoxy-4-(methoxymethyl)aconitane-1,7,14-triol. Grades: 98.0%. CAS No. 92631-66-8. Molecular formula: C25H41NO7. Mole weight: 467.603.
Demethoxycapillarisin
Demethoxycapillarisin is a natural flavonoid found in the roots of Saposhnikovia divaricata. Alternative Names: 5,7-dihydroxy-2-(4-hydroxyphenoxy)chromen-4-one. Grades: >97%. CAS No. 61854-36-2. Molecular formula: C15H10O6. Mole weight: 286.24.
Demethylcephalotaxinone
Demethylcephalotaxinone is a natural alkaloid compound found in several plants. Alternative Names: Desmethylcephalotaxinone;(S)-1-hydroxy-5,6,8,9-tetrahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-2(3H)-one. Grades: >95%. CAS No. 51020-45-2. Molecular formula: C17H17NO4. Mole weight: 299.32.
Demethylmurrayanine
Demethylmurrayanine is a natural alkaloid found in the herbs of Clausena dunniana. Alternative Names: 3-Formyl-1-hydroxycarbazole; O-Demethylmurrayanine. Grades: >95%. CAS No. 123497-84-7. Molecular formula: C13H9NO2. Mole weight: 211.22.
Demethylvestitol
Demethylvestitol is a flavonoid isolated from the herbs of Spatholobus suberectus. Uses: Neuromuscular nondepolarizing agents. Alternative Names: 7,2',4'-Trihydroxyisoflavan. Grades: > 95%. CAS No. 65332-45-8. Molecular formula: C15H14O4. Mole weight: 258.3.
Demethylzeylasteral
Demethylzeylasteral is extracted from the herb of Tripterygium wilfordii Hook.f. It may be used as an immunosuppressive agent in the fields of organ transplantation and autoimmune disorders. It could increase both activation and inactivation time constants of Ca(2+) currents. Alternative Names: (9beta,13alpha,14beta,20alpha)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid; A-Friedo-24-noroleana-1,3,5(10),7-tetraen-29-oic acid. Grades: >98%. CAS No. 107316-88-1. Molecular formula: C29H36O6.
Demiditraz Racemate
A racemate form of Demiditraz, which is an acaricide agent. Alternative Names: 2-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole. CAS No. 944263-08-5. Molecular formula: C13H16N2. Mole weight: 200.28.
Dendrobine
Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord. Uses: Analgesic / antipyretic. Alternative Names: (3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one; Dendroban-12-one; 12-Oxodendrobane; 7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-; Dendrobine Dendroban-12-one. Grades: >98%. CAS No. 2115-91-5. Molecular formula: C16H25NO2. Mole weight: 263.38.
Denibulin
Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. The results of preclinical study demonstrated that MN-029 could cause rapid vascular shutdown in solid tumors, dose-dependent secondary tumor cell killing, and effective enhancement of the antitumor effects of radiation and cisplatin chemotherapy. Alternative Names: MN-029; MN 029; MN029; (S)-methyl (5-((4-(2-aminopropanamido)phenyl)thio)-1H-benzo[d]imidazol-2-yl)carbamate. Grades: 95%. CAS No. 284019-34-7. Molecular formula: C18H19N5O3S. Mole weight: 385.44.
Deoxyaconitine
3-Deoxyaconitine is an alkaloid isolated from Aconitum Carmichaeli Debx. Alternative Names: Deoxyaconitine. Grades: 98%. CAS No. 3175-95-9. Molecular formula: C34H47NO10. Mole weight: 629.74.
Deoxyandrographolide
Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees. It could potently inhibit the growth of liver (HepG2 and SK-Hep1) and bile duct (HuCCA-1 and RMCCA-1) cancer cells. It controlled ethanol-induced hepatosteatosis by interfering with dysregulation of lipid metabolism. It was capable of preventing the development of fatty liver through AMPK-mediated regulation of lipid metabolism. It reduced the extracellular acidification rate and the intracellular alkalinization in a dose-dependent manner in concentrations between 10-100 microM. It reduced PAF-induced calcium flux in the presence of extracellular calcium. It mediated activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS may provide a promising approach in the prevention of liver diseases during chronic alcoholism. Uses: Deoxyandrographolide could potently inhibit the growth of liver (hepg2 and sk-hep1) and bile duct (hucca-1 and rmcca-1) cancer cells. it controlled ethanol-induced hepatosteatosis by interfering with dysregulation of lipid metabolism. it reduced the extracellular acidification rate and the intracellular alkalinization in a dose-dependent manner in concentrations between 10-100 microm. it reduced p. Alternative Names: 4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one;2(5H)-Furanone, 3-[2-[(4
Deoxycalyciphylline B
Deoxycalyciphylline B is isolated from the herbs of Daphniphyllum calycinum. Uses: Hepatic toxicity. Alternative Names: (2S,2aR,4aS,8aR,8bS,10aR,13bR,13dS)-2,8a-Dimethyl-1,2,2a,3,4,5,6, 8a,8b,9,10,10a,11,12,13b,13d-hexadecahydro-7H-8-oxa-13c-azacyclop enta[a]pentaleno[1,6-kl]phenanthren-7-one. Grades: 0.98. CAS No. 619326-74-8. Molecular formula: C22H31NO2. Mole weight: 341.5.
Deoxydonepezil
Deoxydonepezil is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Alternative Names: Donepezil Deoxy Impurity; Piperidine, 4-((2,3-dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl)-1-(phenylmethyl)-. CAS No. 844694-84-4. Molecular formula: C24H31NO2. Mole weight: 365,517.
Deoxyelephantopin
Deoxyelephantopin is a natural sesquiterpenoid found in the herbs of Elephantopus scaber Linn. Deoxyelephantopin has hepatoprotective and antitumor activities. Uses: Hepatoprotective, antitumor. Alternative Names: 2-Methylpropenoic acid (3aR,4S,9R,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-2,7-dioxo-11-methyl-3-methylene-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester. Grades: >97%. CAS No. 29307-03-7. Molecular formula: C19H20O6. Mole weight: 344.36.
Deoxyisocalyciphylline B
Deoxyisocalyciphylline B is isolated from the herbs of Daphniphyllum calycinum. Alternative Names: (2S,2aR,4aS,8aS,8bS,10aR,13bR,13dS)-2,8a-Dimethyl-1,2,2a,3,4,5,6, 8a,8b,9,10,10a,11,12,13b,13d-hexadecahydro-7H-8-oxa-13c-azacyclop enta[a]pentaleno[1,6-kl]phenanthren-7-one. Grades: 98%. CAS No. 619326-75-9. Molecular formula: C22H31NO2. Mole weight: 341.5.
Deoxysotalol hydrochloride
An impurity of Sotalol. Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties. Alternative Names: Sotalol EP Impurity A Hydrochloride; Sotalol USP Related Comopound C; Deshydroxy Sotalol Hydrochloride; N-(4-(2-((1-Methylethyl)amino)ethyl)phenyl)methanesulfonamide monohydrochloride. Grades: ≥95%. CAS No. 16974-44-0. Molecular formula: C12H21ClN2O2S. Mole weight: 292.83.
Dermaseptin TFA
Dermaseptin TFA. CAS No. 646451-06-1.
Derrisisoflavone H
Derrisisoflavone H is a natural compound, armed with potent anti-inflammatory attributes. This marvel stands poised to revolutionize the research of inflammation-centric afflictions and even specific cancer variants. Alternative Names: Derrisisoflavone H; AKOS040762675; 2172624-65-4. Grades: 93.0%. CAS No. 2172624-65-4. Molecular formula: C26H26O7. Mole weight: 450.49.
Derrisisoflavone I
Derrisisoflavone I is a extensively utilized natural compound in the biomedical industry, presenting itself as a promising candidate for drug development of a range of afflictions characterized by inflammation, such as rheumatoid arthritis is asthma and inflammatory bowel disease. Alternative Names: Derrisisoflavone I; AKOS040762672; 2172624-66-5. Grades: 95.0%. CAS No. 2172624-66-5. Molecular formula: C26H26O7. Mole weight: 450.49.
Derrisisoflavone K
Derrisisoflavone K is a bioactive constituent derived from Derris species, garnering immense interest due to its multifaceted applications in various biomedical domains. This natural compound exhibits profound anti-inflammatory and anticancer properties, rendering it a potential option for studying ailments such as arthritand certain forms of malignancy. Grades: 98.0%. CAS No. 2172624-68-7. Molecular formula: C22H22O6. Mole weight: 382.41.
Des(2-methylbutyryl) Lovastatin Hydroxy Acid Sodium Salt
An impurity of Lovastatin. Lovastatin is an HMG CoA reductase inhibitor used to treat high blood cholesterol. Alternative Names: 3,5-Dihydroxy-7-(8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)heptenoate Acid Sodium Salt; [1S-[1α(βS*,δS*),2β,6β,8β,8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,8-trihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt. Grades: > 95%. CAS No. 132294-94-1. Molecular formula: C19H29O5Na. Mole weight: 360.42.
Des-(3-(Pyridin-2-ylamino)propanoate)Dabigatran Ethyl Ester is an impurity of Dabigatran. Dabigatran is a very potent anticoagulant, in which the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Alternative Names: Ethyl 2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylate. CAS No. 1408238-41-4. Molecular formula: C19H21N5O2. Mole weight: 351.41.
Des-4-fluorobenzyl Mosapride
Des-4-fluorobenzyl Mosapride is an impurity of Mosapride. Mosapride is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Alternative Names: Des-p-fluorobenzyl mosapride; Mosapride Impurity 5; 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide. Grades: 95%. CAS No. 152013-26-8. Molecular formula: C14H20ClN3O3. Mole weight: 313.79.
Desacetyl-7-ACA lactone
Desacetyl-7-ACA lactone is a lactone derivative of 7-Aminocephalosporanic acid, a fundamental building block in the synthesis of cephalosporin antibiotics. Alternative Names: (5aR,6R)-6-Amino-5a,6-dihydro-3H,7H-Azeto[2,1-b]furo[3,4-d][1,3]thiazine-1,7(4H)-dione; (5aR-trans)-6-amino-5a,6-dihydro-3H,7H-Azeto[2,1-b]furo[3,4-d][1,3]thiazine-1,7(4H)-dione. Grades: > 95%. CAS No. 184696-69-3. Molecular formula: C8H8N2O3S. Mole weight: 212.23.
Desacetylcinobufagin
Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation. Alternative Names: 3-beta,16-beta-Dihydroxy-14,15-beta-epoxy-5-beta-bufa-20,22-dienolide; Deacetylcinobufagin; Cinobufagin, deacetyl- (6CI). Grades: ≥95%. CAS No. 4026-95-3. Molecular formula: C24H32O5. Mole weight: 400.51.
Desacetyl-N,O-descarbonyl Linezolid
Desacetyl-N,O-descarbonyl Linezolid is an impurity of Linezolid, an oxazolidinone antimicrobial that inhibits bacterial mRNA translation. Alternative Names: (2S)-1-Amino-3-[[3-fluoro-4-(4-morpholinyl)phenyl]amino]-2-propanol. Grades: > 95%. CAS No. 333753-72-3. Molecular formula: C13H20FN3O2. Mole weight: 269.32.
Descyclopropyl-dicyclanil-[15N3]
Des cyclopropyl dicyclanil-15N3 is a labelled impurty of dicyclanil, which can be used as a veterinary drug. Alternative Names: 2,4,6-Triamino-15N3-pyrimidine-5-carbonitrile; Descyclopropyl-dicyclanil-15N3. Grades: 95% by HPLC; 98% atom 15N. Molecular formula: C5H6N3[15N]3. Mole weight: 153.12.
Desethyl Chloroquine
The major product of the stereoselective human metabolism of Chloroquine, a medication used for the therapy and prevention of malaria. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine; Deethylchloroquine; Monodeethylchloroquine. Grades: > 95%. CAS No. 1476-52-4. Molecular formula: C16H22ClN3. Mole weight: 291.82.
Desisobutyryl Ciclesonide
Desisobutyryl Ciclesonide is the preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma. Alternative Names: (11β,16α)-16,17-[[(R)-Cyclohexylmethylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione; CIC-AP; Ciclesonide active principle. Grades: > 95%. CAS No. 161115-59-9. Molecular formula: C28H38O6. Mole weight: 470.61.
Desmethoxyyangonin
5,6-dehydrokawain is a natural compound found in beverages and kava. It acts as a MAO-B inhibitor. Uses: Inhibitor of mao-b. Alternative Names: Demethoxyyangonin; Desmethoxy Yangonin. Grades: >98%. CAS No. 15345-89-8. Molecular formula: C14H12O3. Mole weight: 228.247.
Desmethyl Celecoxib
An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Alternative Names: 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Grades: >95%. CAS No. 170569-87-6. Molecular formula: C16H12F3N3O2S. Mole weight: 367.346.
Desmethyl Erlotinib
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol. Grades: > 95%. CAS No. 183321-86-0. Molecular formula: C21H21N3O4. Mole weight: 379.42.
Desmethyl Telmisartan
One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Alternative Names: N-Desmethyl telmisartan; 4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid. Grades: > 95%. CAS No. 144701-81-5. Molecular formula: C32H28N4O2. Mole weight: 500.61.