BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| DUPA(OtBu)-OH | DUPA(OtBu)-OH is a PEG linker for antibody-drug-conjugation (ADC). DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. Alternative Names: (S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid; L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester; 2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester. Grades: 95%. CAS No. 1026987-94-9. Molecular formula: C23H40N2O9. Mole weight: 488.57. |  |
| Duvelisib | Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta / gamma inhibitor IPI 145 prevents the activation of the PI3K delta / gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta / gamma-expressing tumor cells. Unlike other isoforms of PI3K, the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases. By selectively targeting these PI3K isoforms, PI3K signaling in normal, non-neoplastic cells is minimally or not affected which would result in a more favorable side effect profile. Uses: For research used only. Alternative Names: IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197; Duvelisib. CAS No. 1201438-56-3. Molecular formula: C22H17ClN6O. Mole weight: 416.869. | |
| D-Val(10)-Semaglutide | D-Val(10)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-[Val]10-Semaglutide; D-[Val]-10-Semaglutide; (3S,9S,12S,15S,18S,21S,24R,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic Acid. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Val(27)-Semaglutide | D-Val(27)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-Val-27-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Valganciclovir Hydrochloride | D-Valganciclovir is the D-isomer of Valganciclovir, which is an antiviral prescription medicine for the treatment of cytomegalovirus retinitis (CMV retinitis) in adults with AIDS. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride; Valganciclovir Isomer. Grades: 95%. CAS No. 1393911-57-3. Molecular formula: C14H23ClN6O5. Mole weight: 390.82. | |
| DXD | DXD, an Exatecan derivative for ADC, is a potent DNA topoisomerase I inhibitor with an IC50 of 0.31 μM. It can be used as a payload for antibody-conjugated drug ADCs targeting HER2. Alternative Names: N-((1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinolin-1-yl)-2-hydroxyacetamide. Grades: ≥95%. CAS No. 1599440-33-1. Molecular formula: C26H24FN3O6. Mole weight: 493.48. | |
| Dydrogesterone EP Impurity A | An impurity of Dydrogesterone. Dydrogesterone is a steroidal progestin of the retroprogesterone group. It can be used as an effective progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. Alternative Names: 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione. Grades: 95%. CAS No. 23035-53-2. Molecular formula: C21H26O2. Mole weight: 310.43. | |
| E260 | E260 is a Fer / FerT kinase inhibitor with Kd of 0.85 uM, which selectively evokes metabolic stress and necrotic death in cancer cells. Alternative Names: E260; E 260; E-260; 2-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]-6-(4-propan-2-ylphenyl)imidazo[2,1-b][1,3,4]thiadiazole. CAS No. 1241537-79-0. Molecular formula: C24H34N6S. Mole weight: 438.638. | |
| E3330 | E3330 is a potent and selective APE1 (Ref-1) inhibitor, which inhibits NF-κB DNA-binding activity. It blocks TNF-α-induced activation of IL-8 production in liver cancer cell lines and has anticancer properties such as inhibiting the growth and migration of cancer cells. Alternative Names: APX-3330; E-3330; E 3330; (2E)-2-[(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene]-undecanoic acid; (E)-2-((4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylene)undecanoic acid; Undecanoic acid, 2-((4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene)-, (E)-. Grades: 98%. CAS No. 136164-66-4. Molecular formula: C21H30O6. Mole weight: 378.46. | |
| E6446 dihydrochloride | E6446 is a novel synthetic antagonist for nucleic acid-sensing TLRs. Alternative Names: E-6446 dihydrochloride; E 6446 dihydrochloride; E6446 dihydrochloride; 6-(3-(pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole dihydrochloride. CAS No. 1345675-25-3. Molecular formula: C27H37Cl2N3O3. Mole weight: 522.51. | |
| (E)-6,6-dimethoxyhex-4-en-3-ol-[d5] | (E)-6,6-dimethoxyhex-4-en-3-ol-[d5]. Alternative Names: (4E)-6,6-Dimethoxy(1,1,1,2,2-2H5)-4-hexen-3-ol; trans-4-Hydroxy-2-hexenal-5,5,6,6,6-d5 Dimethyl Acetal. Grades: 99% atom D. CAS No. 1219806-40-2. Molecular formula: C8H11D5O3. Mole weight: 165.24. | |
| (E)-8-Methyl-6-nonenoic acid | (E)-8-Methyl-6-nonenoic acid is a thermal degradant of Capsaicin. Alternative Names: 8-methylnonenoate; 8-Methyl-6-nonenoic acid; (E)-8-methylnon-6-enoic acid. Grades: >95%. CAS No. 59320-77-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| EAI045 | EAI045 is an allosteric, non-ATP competitive inhibitor of mutant EGFR. In vitro studies proved that EAI045 is active and selective for T790M- harboring EGFR mutants that are in a monomer state. In vivo the combination of EAI045 and cetuximab caused a marked tumor shrinkage in a mouse model carrying the EGFR mutant with L858R/T790M/C797S. Therefore, EAI045 is the first allosteric inhibitor that targets T790M and C797S EGFR mutants but it is effective only in combination with cetuximab. Alternative Names: 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide; 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide; EAI045; EAI 045; EAI-045. CAS No. 1942114-09-1. Molecular formula: C19H14FN3O3S. Mole weight: 383.397. | |
| (E)-Aldosecologanin | (E)-Aldosecologanin is a natural iridoid found in the herbs of Lonicera japonica. Alternative Names: (2S,2'S,3R,3'R,4R,4'S)-4,4'-[(1E)-1-Formyl-1-propene-1,3-diyl]bis[3-ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylic acid] dimethyl ester; 2H-Pyran-5-carboxylic acid, 4,4'-[(1E)-1-formyl-1-propene-1,3-diyl]bis[3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-, 5,5'-dimethyl ester, (2S,2'S,3R,3'R,4R,4'S)-; 2H-Pyran-5-carboxylic acid, 4,4'-[(1E)-1-formyl-1-propene-1,3-diyl]bis[3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-, dimethyl ester, (2S,2'S,3R,3'R,4R,4'S)-. Grades: >97%. CAS No. 471271-55-3. Molecular formula: C34H46O19. Mole weight: 758.73. | |
| EBDC-Dimethyl-[d6] | EBDC-Dimethyl-[d6]. Alternative Names: Dimethyl-D6-N,N'-ethylenebis(dithiocarbamate). Molecular formula: C6H6D6N2S4. Mole weight: 246.45. | |
| Ebeiedinone | Ebeiedinone is a cutting-edge natural compound used in the research of multiple diseases, including cancer and infectious diseases. Alternative Names: Ebwardine. Grades: >98%. CAS No. 25650-68-4. Molecular formula: C27H43NO2. Mole weight: 413.646. | |
| Ecamsule.2Na | Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves / protective clothing/eye protection / face protection. Uses: Sunscreening agents. Alternative Names: Sodium ((1,4-phenylenebis(methanylylidene))bis(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl-3-ylidene))dimethanesulfonate. Grades: ≥ 95.0%. CAS No. 90458-75-6. Molecular formula: C28H32Na2O8S2. Mole weight: 606.66. | |
| Ecdysterone 20,22-monoacetonide | Ecdysterone 20,22-monoacetonide isolated from the roots of Cyanotis arachnoidea C. B. Clarke. Alternative Names: 20-hydroxyecdysone 20,22-acetonide; (2β,3β,5β,17β)-2,3,14-Trihydroxy-17-[(4R,5R)-5-(3-hydroxy-3-methy lbutyl)-2,2,4-trimethyl-1,3-dioxolan-4-yl]androst-7-en-6-one. Grades: 0.98. CAS No. 22798-96-5. Molecular formula: C30H48O7. Mole weight: 520.7. | |
| Ecdysterone 2,3:20,22-diacetonide | Ecdysterone 2,3:20,22-diacetonide isolated from the roots of Cyanotis arachnoidea C. B. Clarke. Alternative Names: 20-hydroxy-23,24-dinor-chol-4-en-3-one. Grades: 0.97. CAS No. 22798-98-7. Molecular formula: C33H52O7. Mole weight: 560.8. | |
| (E)-Ceftriaxone disodium salt | (E)-Ceftriaxone disodium salt. CAS No. 97164-54-0. | |
| (E)-Cefuroxime axetil | (E)-Cefuroxime axetil is the (E)-isomer of cefuroxime axetil, a prodrug form of the second-generation cephalosporin antibiotic cefuroxime. The E configuration refers to the stereochemistry of the oxime group on the β-lactam core, which is in the trans orientation. This isomer is the therapeutically active form, contributing to its antibacterial efficacy. Cefuroxime axetil improves the oral bioavailability of cefuroxime by utilizing the acetoxyethyl ester as a prodrug, which is hydrolyzed in vivo to release the active drug. It acts by inhibiting bacterial cell wall synthesis via binding to penicillin-binding proteins (PBPs). This compound is effective against a wide range of Gram-positive and Gram-negative bacteria and is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections. Alternative Names: 1-Acetoxyethyl (6R,7R)-3-((carbamoyloxy)methyl)-7-((E)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefuroxime Axetil E-Isomer Impurity 1; 1-(Acetyloxy)ethyl (6R,7R)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2E)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-c. Grades: ≥95%. CAS No. 97232-96-7. Molecular formula: C20H22N4O10S. Mole weight: 510.47. | |
| Echitamine | Echitamine, a natural indole alkaloid found in the herbs of Alstonia scholaris, exhibits the activity of anti-tumour activity in-vitro and in-vivo. Uses: Anti-tumour. Alternative Names: (16R)-3β,17-Dihydroxy-16-(methoxycarbonyl)-4-methyl-2,4(1H)-cyclo-3,4-secoakuammilan-4-ium. Grades: >98%. CAS No. 6871-44-9. Molecular formula: C22H29N2O4. Mole weight: 385.5. | |
| Echitovenidine | Echitovenidine is an alkaloid isolated from the fruits of Alstonia venenata. In vitro and in vivo studies revealed that echitovenidine has an inhibitory effect on monoamine oxidase. Alternative Names: Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-((3-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (5-alpha,12-beta,19-alpha,20R)-. Grades: 97.5%. CAS No. 7222-35-7. Molecular formula: C26H32N2O4. Mole weight: 436.552. | |
| Echitoveniline | Echitoveniline is an alkaloid isolated from the fruits and leaves of Alstonia venenata R.Br. Alternative Names: Echitoveniline; 72855-79-9; HY-N9161; AKOS040761655; CS-0158870; methyl (1R,12R,19R)-12-[(1R)-1-(3,4,5-trimethoxybenzoyl)oxyethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate. Grades: 98.0%. CAS No. 72855-79-9. Molecular formula: C31H36N2O7. Mole weight: 548.636. | |
| Edaravone-[d5] | Edaravone-[d5] is a deuterium labelled form of Edaravone. Edaravone is an intravenous medication used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis. Alternative Names: 2,4-Dihydro-5-methyl-2-(phenyl-2,3,4,5,6-d5)-3H-pyrazol-3-one; Edaravone D5. CAS No. 1228765-67-0. Molecular formula: C10H5D5N2O. Mole weight: 179.23. | |
| Edaravone Impurity III | Edaravone Impurity. Alternative Names: 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoic acid; 2-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-sulfopropanoic acid; Edaravone Impurity III; Edaravone IMpurity P1; DTXSID80855974; BCP18301; AC-30014; B0060-462129; 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoicacid. Grades: > 95%. CAS No. 1357477-99-6. Molecular formula: C13H14N2O6S. Mole weight: 326.33. | |
| Edaravone impurity P3 | Edaravone Impurity. Alternative Names: Edaravone Impurity VI. Grades: > 95%. CAS No. 1323485-71-7. Molecular formula: C13H16N2O4S. Mole weight: 296.35. | |
| Edonerpic maleate | The maleate salt form of Edonerpic, which is a neuroproptectant. Edonerpic is in clinical trials for the treatment of Alzheimer's disease (AD). It inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor, as well as it may be beneficial for the treatment of neurodegenerative disorders related to oxidative stress, such as Parkinson's disease. Uses: Candidate therapeutic agent for alzheimer's disease. Alternative Names: T-817 maleate; T-817MA; 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol maleate. CAS No. 519187-97-4. Molecular formula: C20H25NO6S. Mole weight: 407.48. | |
| Edoxaban impurity I | The enantiomer of Edoxaban, Edoxaban Impurity. Alternative Names: N-(5-Chloropyridin-2-yl)-N'-[(1R,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. Grades: > 95%. CAS No. 1255529-23-7. Molecular formula: C24H30ClN7O4S. Mole weight: 548.07. | |
| EED-226 | EED-226 is a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor (IC50 = 23.4 nM when the substrate is H3K27me0 peptide and IC50 = 53.5 nM when the substrate is mononucleosom). EED-226 induces a conformational change via binding EED which invalidates PRC2 activity. PRC2 plays pivotal roles in transcriptional regulation. EED-226 has the potential to treat PRC2-dependent cancers, such as human lymphoma xenograft tumors. Alternative Names: EED226; EED-226; EED 226. N-(2-furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine. Grades: 98%. CAS No. 2083627-02-3. Molecular formula: C17H15N5O3S. Mole weight: 369.4. | |
| Effusol | Effusol is a metabolite of Dihydrophenanthrene that is found in the Juncus effusus L. Effusol. It exhibits antitumor activity. Alternative Names: 5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol; 1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol. Grades: >98%. CAS No. 73166-28-6. Molecular formula: C17H16O2. Mole weight: 252.313. | |
| Effususol A | Effususol A is a natural compound used in the research of various types of cancer. With its unique chemical composition, this product has shown promising results in inhibiting the growth and proliferation of tumor cells. Grades: 98.0%. CAS No. 1869082-58-5. Molecular formula: C18H20O3. Mole weight: 284.355. | |
| Efinaconazole | Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Alternative Names: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia. Grades: >98%. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39. | |
| EGF816 | EGF816, also called as Nazartinib, a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M resistance mutation while sparing wild-type EGFR. in vivo: demonstrated strong tumor regressions in several EGFR activating and resistant tumor m. Alternative Names: EGF816; EGF-816; EGF 816; NVS-816; NVS 816; NVS816; Nazartinib; N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamideEGF816UNII-KE7K32EME8KE7K32EME8EGF-8161508250-71-2GTPL9204SCHEMBL16767232SCHEMBL16767240EGF 816compound 47 [PMID: 27433829]. CAS No. 1508250-71-2. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. | |
| Ehp-inhibitor-1 | Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Alternative Names: 6-(3-methoxyphenyl)-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 861249-59-4. Molecular formula: C18H15N5O. Mole weight: 317.352. | |
| Ehp-inhibitor-2 | Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Alternative Names: 3-(7-amino-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol. CAS No. 861249-77-6. Molecular formula: C17H13N5O. Mole weight: 303.325. | |
| EIDD-1931 | EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Alternative Names: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. It binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. Alternative Names: eIF4A3-IN-1; 2095486-67-0; CHEMBL4073833; BDBM50265561; AKOS040733081; MS-30511; HY-101513; CS-0021616; 3-[4-[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)piperazine-1-carbonyl]-5-methylpyrazol-1-yl]benzonitrile. Grades: 99%. CAS No. 2095486-67-0. Molecular formula: C29H23BrClN5O2. Mole weight: 588.88. | |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Alternative Names: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. | |
| (E)-KPT330 | (E)-Kpt-330 is an E-isomer of Kpt-330, also known as Selinexor, which is an orally available inhibitor of CRM1 with potential antineoplastic activity. Alternative Names: (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; Selinexor trans-isomer; KPT-330, (E)-; UNII-MVY2AE6R24; MVY2AE6R24; KPT330,(E)-; 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyrazinyl)hydrazide, (2E)-; 1421923-86-5 (E-isomer); KPT330Selinexor; O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2E)-; (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide. Grades: ≥95%. CAS No. 1421923-86-5. Molecular formula: C17H11F6N7O. Mole weight: 443.3. | |
| Elbasvir | Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis C virus and is currently under Phase II trail. Uses: Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis c virus and is currently under phase ii trail. Alternative Names: Elbasvir; MK-8742; UNII-632L571YDK; 632L571YDK; MK8742; MK 8742. Grades: 98%. CAS No. 1370468-36-2. Molecular formula: C49H55N9O7. Mole weight: 882.02. | |
| Eldecalcitol Intermediate CD | Eldecalcitol Intermediate CD is a vital component used in the compound industry. Specifically designed for pharmaceutical applications, this intermediate plays a crucial role in the synthesis of Eldecalcitol, a drug used for the research of osteoporosand other bone-related disorders. Alternative Names: ED71-CD ring; 25-[(triethylsilyl)oxy]de-A,B-cholestan-8-one; (1R,3aR,7aR)-7a-Methyl-1-((R)-6-methyl-6-((triethylsilyl)oxy)heptan-2-yl)hexahydro-1H-inden-4(2H)-one. CAS No. 144848-24-8. Molecular formula: C24H46O2Si. Mole weight: 394.71. | |
| Elesclomol | Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp. Alternative Names: STA4783; STA-4783; STA 4783, Elesclomol. CAS No. 488832-69-5. Molecular formula: C19H20N4O2S2. Mole weight: 400.52. | |
| Eleutheroside C | Eleutheroside C is isolated from the root barks of Eleutherococcus senticosus. Alternative Names: ethyl alpha-d-galactopyranoside. Grades: > 95%. CAS No. 15486-24-5. Molecular formula: C8H16O6. Mole weight: 208.2. | |
| Eliprodil | Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Alternative Names: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. Grades: 95%. CAS No. 119431-25-3. Molecular formula: C20H23ClFNO. Mole weight: 347.85. | |
| ELOVL1-IN-2 | ELOVL1-IN-2 is an inhibitor of ELOVL1 (elongation of very-long-chain-fatty acid 1). CAS No. 2761063-79-8. Molecular formula: C18H15FN2O. Mole weight: 294.3. | |
| ELQ-300 | ELQ-300 is a potent and orally bioavailable antimalarial agent, and it is a novel inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (complex III in the electron transport chain). Alternative Names: ELQ300; ELQ 300; 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one. Grades: ≥98%. CAS No. 1354745-52-0. Molecular formula: C24H17ClF3NO4. Mole weight: 475.84. | |
| Eltoprazine hydrochloride | Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine hydrochloride has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Alternative Names: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, monohydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;DU-28853 hydrochloride;DU28853 hydrochloride. Grades: >98 %. CAS No. 98206-09-8. Molecular formula: C12H17N2O2Cl. Mole weight: 256.73. | |
| Emapunil | Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects. Alternative Names: AC-5216; AC 5216; AC5216; XBD-173; XBD 173; XBD173; Emapunil. Grades: >98%. CAS No. 226954-04-7. Molecular formula: C23H23N5O2. Mole weight: 401.46. | |
| Emeheterone | Emeheterone is a pyrazinone derivative found in mericella heterothallica. Alternative Names: 3,6-dibenzyl-5-methoxy-4-oxido-1H-pyrazin-4-ium-2-one. Grades: 98.0%. CAS No. 117333-12-7. Molecular formula: C19H18N2O3. Mole weight: 322.364. | |
| Emodin anthrone | Emodin anthrone is a natural product found in Rhamnus prinoides, Paeonia emodi, and Rumex acetosa with data available. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli. Alternative Names: Emodinanthrone; emodin-9-anthrone; Emodinol; Protophyscihydrone; 2,4,5-trihydroxy-7-methylanthracen-10(9H)-one. Grades: 95%. CAS No. 491-60-1. Molecular formula: C15H12O4. Mole weight: 256.25. | |
| Emopamil | Emopamil is a calcium channel blocker that can be used to prevent renal injury after warm & cold ischemia. Uses: Calcium channel blockers. Alternative Names: Emopamil; 78370-13-5; Emopamil [INN]; Emopamilum [Latin]; Emopamilo [Spanish]. Grades: 95%. CAS No. 78370-13-5. Molecular formula: C23H30N2. Mole weight: 334.504. | |
| Empagliflozin-[d4] | An isotope labelled of Empagliflozin. Empagliflozin is ued for the treatment of type 2 diabetes in adults. Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol-d4. Grades: 95% by HPLC; 98% atom D. Molecular formula: C23H23D4ClO7. Mole weight: 454.94. | |
| Empagliflozin Impurity 17 | An impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: (2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol; Tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl). CAS No. 2452301-27-6. Molecular formula: C23H28O7. Mole weight: 416.46. | |
| Empagliflozin R-Furanose | Empagliflozin R-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: Canagliflozine Furanose Impurity; (2R,3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-31-7. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin S-Furanose | Empagliflozin S-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: Jardiance Impurity C; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-32-8. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Tetraacetoxy | Empagliflozin Tetraacetoxy is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: 1-Methoxy-Empagliflozin Tetraacetoxy; (S)-3-(4-(2-chlorobenzyl)phenoxy)tetrahydrofuran; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-, 2,3,4,6-tetraacetate. Grades: 95%. CAS No. 1620758-21-5. Molecular formula: C32H37ClO12. Mole weight: 649.08. | |
| Enalaprilat Dihydrate | Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor. Grades: >98%. CAS No. 84680-54-6. Molecular formula: C18H28N2O7. Mole weight: 384.42. | |
| Enalapril EP Impurity D | An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Alternative Names: Enalapril diketopiperazine; Ethyl (2S)-2-[(3S,8aS)-3-methyl-1,4-dioxooctahydropyrrolo [1,2-a]pyrazin-2-yl]-4-phenylbutanoate. Grades: > 95%. CAS No. 115729-52-7. Molecular formula: C20H26N2O4. Mole weight: 358.44. | |
| Enalapril EP Impurity G | An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Alternative Names: (2S)-2-[[(1S)-3-Cyclohexyl-1-(ethoxycarbonyl)propyl]amino] propanoic acid. Grades: > 95%. CAS No. 460720-14-3. Molecular formula: C15H27NO4. Mole weight: 285.39. | |
| Enasidenib | Enasidenib, aslo known as AG-221 and CC-90007, is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2). Alternative Names: AG-221; AG 221; AG221; CC-90007; CC 90007; CC90007; Enasidenib. Grades: 98%. CAS No. 1446502-11-9. Molecular formula: C19H17F6N7O. Mole weight: 473.38. | |
| endo-BCN-PNP-carbonate | endo-BCN-O-PNB is a PROTAC linker, which is composed of alkyl chains. endo-BCN-O-PNB can be used to synthesize a range of PROTACs. Alternative Names: BCN-PNP (endo);endo-BCN-O-PNB; endo-BCN-PNP-carbonate; rel-((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (4-nitrophenyl) carbonate; BCN-OPNP. Grades: 95%. CAS No. 1263166-91-1. Molecular formula: C17H17NO5. Mole weight: 315.32. | |
| ENMD-2076 | ENMD-2076 is an orally-active, Aurora A / angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD-2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over-expressed in human cancers. ENMD-2076 also targets the VEGFR, Flt-3 and FGFR3 kinases which have been shown to play important roles in the pathology of several cancers. ENMD-2076 has shown promising activity in Phase 1 clinical trials in solid tumor cancers, leukemia, and multiple myeloma. ENMD-2076 is currently in a Phase 2 trial for ovarian cancer, and preclinical and clinical activities are ongoing in assessing the compound's applicability for other forms of cancer. Alternative Names: ENMD-2076; ENMD 2076; ENMD2076. CAS No. 934353-76-1. Molecular formula: C21H25N7. Mole weight: 375.47. | |
| Enmein | Enmein is a natural diterpenoid compound found in several plants. Alternative Names: Isodonin. Grades: >98%. CAS No. 3776-39-4. Molecular formula: C20H26O6. Mole weight: 362.42. | |
| Enrofloxacin-[d5] | Enrofloxacin-[d5] is the labelled analogue of Enrofloxacin, which is a fluoroquinolone antibiotic. Enrofloxacin is used in the treatment of individual pets and domestic animals. Alternative Names: Enrofloxacin D5; 1-Cyclopropyl-7-[4-(ethyl-d5)-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; CFPQ-d5; Baytril-d5. Grades: ≥99%; ≥99% atom D. CAS No. 1173021-92-5. Molecular formula: C19H17D5FN3O3. Mole weight: 364.43. | |
| ent-11α,15α-Dihydroxykaur-16-en-19-oic acid | ent-11α,15α-Dihydroxykaur-16-en-19-oic acid is a natural diterpenoid found in the herbs of Cerbera manghas. Alternative Names: 11,15-Dihydroxy-16-kauren-19-oic acid. Grades: >98%. CAS No. 57719-76-3. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| ent-11α,16α-Epoxy-15α-hydroxykauran-19-oic acid | ent-11,16-Epoxy-15-hydroxykauran-19-oic acid is isolated from the herbs of Nouelia insignis. Alternative Names: (4alpha,11beta,15beta,16alpha)-11,16-Epoxy-15-hydroxykauran-18-oic acid; (5β,8α,9β,10α,11α,13α,15β)-15-Hydroxy-11,16-epoxykauran-18-oic acid. Grades: 97.5%. CAS No. 77658-46-9. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide | ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide is extracted from the roots of Euphorbia ebracteolata. It has significant cytotoxic activity against Jurkat and ANA-1 cells with IC50 values 1.79 x 10(-2) and 7.12 x 10(-3) microM. Alternative Names: 130466-20-5; (4Ar,10aS,11R,11aR,11bR)-11-hydroxy-4,4,8,11b-tetramethyl-2,3,4a,5,6,10a,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-oneent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olideCHEMBL3746967Ent-11-alpha.-Hydroxyabieta-8(14),13(15)-dien-16,12-alpha-olide. Grades: 98.5%. CAS No. 130466-20-5. Molecular formula: C20H28O3. Mole weight: 316.44. | |
| ent-11β-Hydroxyatis-16-ene-3,14-dione | ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity. Alternative Names: (3R,4R,4aS,4bR,8aS,10aS)-4-hydroxy-4b,8,8-trimethyl-12-methylenedecahydro-1H-3,10a-ethanophenanthrene-1,7(2H)-dione. Grades: 97%. CAS No. 1092103-22-4. Molecular formula: C20H28O3. Mole weight: 316.435. | |
| ent-13,16β,17-Trihydroxykauran-19-oic acid | ent-13,16β,17-Trihydroxykauran-19-oic acid has antihyperglycemic activity. Alternative Names: Kauran-18-oic acid, 13,16,17-trihydroxy-, (4α)-; (5β,8α,9β,10α,13α,16β)-13,16,17-Trihydroxykauran-18-oic acid; (4R,4aS,6aS,8S,9S,11aR,11bS)-8,9-dihydroxy-8-(hydroxymethyl)-4,11b-dimethyltetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid. Grades: 98.0%. CAS No. 142543-30-4. Molecular formula: C20H32O5. Mole weight: 352.47. | |
Our database is helping our users find suppliers everyday.
