BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Fennel Oil | Fennel Oil is used in the preparation of fennel, toothpaste flavors, and flavoring agents for medicines, beverages, and foods. CAS No. 8006-84-6. |  |
| Fenofibric Acid 1-Carboxyl-1-methylethyl Ester | An impurity of Fenofibrate. Fenofibrate is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid 1-Carboxyl-1-methylethyl Ester; Fenofibrate Impurity 4. Grades: 98%. CAS No. 1797121-54-0. Molecular formula: C21H21ClO6. Mole weight: 404.85. | |
| Fenvalerate-[d5] | Fenvalerate-[d5] is the labelled analogue of Fenvalerate, which is a synthetic pyrethroid insecticide. Uses: Labelled fenvalerate (f279450). an insecticide, used to control insects from food crops, animal feed and cotton products. Alternative Names: Fenvalerate D5; Fenvalerate-(phenoxy-d5). Grades: 95% atom D. CAS No. 1246815-00-8. Molecular formula: C25H17D5ClNO3. Mole weight: 424.93. | |
| Ferrostatin-1 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. Alternative Names: Fer-1; Fer 1; Fer1; Ferrostatin-1; Ferrostatin 1; Ferrostatin1. Grades: >98%. CAS No. 347174-05-4. Molecular formula: C15H22N2O2. Mole weight: 262.35. | |
| Ferrozine sodium | Ferrozine sodium. CAS No. 69898-45-9. | |
| Ferulamide | Ferulamide isolated from the fruits of Croton tiglium. Alternative Names: 2-PropenaMide, 3-(4-hydroxy-3-Methoxyphenyl)-, (2E)-; 3-(4-Hydroxy-3-methoxyphenyl)acrylamide. Grades: 0.98. CAS No. 61012-31-5. Molecular formula: C10H11NO3. Mole weight: 193.2. | |
| Fexaramine | Fexaramine is a small molecule farnesoid X receptor agonist with 100-fold increased affinity relative to natural compounds. Grades: >98%. CAS No. 574013-66-4. Molecular formula: C32H36N2O3. Mole weight: 496.64. | |
| Fexofenadine EP Impurity C | Fexofenadine EP Impurity C is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Alternative Names: Fexofenadine Hydrochloride EP impurity C; (1RS)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol; Fexofenadine Decarboxylated Degradation Product; Decarboxy Fexofenadine; 4-(Hydroxydiphenylmethyl)-α-[4-(1-methylethyl)phenyl]-1-piperidinebutanol; 1-Piperidinebutanol, 4-(hydroxydiphenylmethyl)-α-[4-(1-methylethyl)phenyl]-; Fexofenadine impurity C; (±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-isopropylbenzene; Fexofenadine Decarboxylated degradant. Grades: ≥95%. CAS No. 185066-37-9. Molecular formula: C31H39NO2. Mole weight: 457.66. | |
| Fexofenadine EP Impurity G | Fexofenadine EP Impurity G is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Alternative Names: Fexofenadine Hydrochloride EP impurity G; 2-[4-[(1RS)-4-[4-(diphenylmethylidene)piperidin-1-yl]-1-hydroxybutyl]phenyl]-2-methylpropanoic acid; Fexofenadine Impurity G; 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid; Benzeneacetic acid, 4-[4-[4-(diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-. Grades: ≥95%. CAS No. 1187954-57-9. Molecular formula: C32H37NO3. Mole weight: 483.66. | |
| FG-2216 | FG-2216, also known as YM311, is an orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. Alternative Names: FG 2216; FG2216; YM311; YM-311; YM 311; N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine. Grades: 98%. CAS No. 223387-75-5. Molecular formula: C12H9ClN2O4. Mole weight: 280.66. | |
| Fiacitabine | Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus(HSV). It was active at much lower concentrations than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine. It was slightly more active against herpes simplex virus type 1 than acycloquanosine and slightly more toxic to normal cells. Uses: Antineoplastic agents. Alternative Names: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine; 5-Iodo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine; FICA; DRG-0077; DRG 0077; DRG0077; FOAC; Fluoroiodoaracytidine; Fluorviodoaracytidine; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 1-β-D-2'-Fluoroarabino-5-iodocytosine; 2'-Fluoro-5-iodo-1-β-D-arabinofuranosylcytosine; NSC 382097. Grades: ≥95%. CAS No. 69123-90-6. Molecular formula: C9H11FIN3O4. Mole weight: 371.10. | |
| Fimasartan | Fimasartan is an angiotensin II receptor blocker (ARB) with selectivity for angiotensin II receptor type 1. Fimasartan is approved in South Korea for the treatment of patients with hypertension and heart failure. Alternative Names: 2-[2-butyl-4-methyl-6-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-5-yl]-N,N-dimethylethanethioamideBR-A657; BR A657; BRA657; BRA 657; Fimasartan. brand name: Kanarb. Grades: >95%. CAS No. 247257-48-3. Molecular formula: C27H31N7OS. Mole weight: 501.6. | |
| Finasteride EP Impurity B | An intermediate in the synthesis of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme. Alternative Names: Dutasteride Methyl ester Imp; Dutasteride Ester Impurity; 4-Azaandrost-1-ene-17-carboxylic acid, 3-oxo-, methyl ester, (5α,17β)-; 17β-(Methoxycarbonyl)-4-aza-5α-androst-1-en-3-one; 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-; 3-Oxo-4-aza-5α-androst-1-en-17β-carboxylic acid methyl ester; Methyl 3-oxo-4-aza-5α-androst-1-ene-17β-carboxylate; Dutasteride methyl ester; Finasteride Methyl Ester Analog. Grades: >95%. CAS No. 103335-41-7. Molecular formula: C20H29NO3. Mole weight: 331.46. | |
| Fingolimod | Fingolimod, a derivative of the fungal metabolite myriocin, is an antagonist of S1P (IC50 of 0.033 nM) which is an extracellular lipid mediator. Fingolimod has been used as an immunomodulating drug to treat multiple sclerosis (MS). Alternative Names: FTY 720; FTY-720; FTY720; 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol. Grades: 95%. CAS No. 162359-55-9. Molecular formula: C19H33NO2. Mole weight: 307.47. | |
| Fingolimod hydrochloride | Fingolimod (FTY720) is a S1P antagonist with IC50 of 0.033 nM. Alternative Names: Fingolimod hydrochloride; FTY720; FTY 720; FTY-720. Grades: >98%. CAS No. 162359-56-0. Molecular formula: C19H33NO2.HCl. Mole weight: 343.9. | |
| FIPI | FIPI, a derivative of halopemide, is a potent and selective phospholipase D (PLD) inhibitor with IC50 values of 20 and 25 nM for PLD2 and PLD1 respectively. It attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. It rapidly blocks in vivo PA production with subnanomolar potency. It has good pharmacokinetic parameters in rats. It did not significantly inhibit p38 or ERK phosphorylation in bone marrow-derived macrophages stimulated with lipopolysaccharide. It prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Alternative Names: 5-Fluoro-2-Indolyl des-Chlorohalopemide; N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide; 5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide. Grades: >98 %. CAS No. 939055-18-2. Molecular formula: C23H24FN5O2. Mole weight: 421.47. | |
| Fipronil-[pyrazole-13C3,cyano-13C] | Labelled Fipronil. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels, resulting in central nervous system toxicity. Alternative Names: 5-Amino-3-cyano-13C-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]pyrazole-13C3. Grades: 98% by HPLC. CAS No. 2140327-54-2. Molecular formula: C8[13C]4H4Cl2F6N4OS. Mole weight: 441.12. | |
| Firategrast | Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). Alternative Names: SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047; Firategrast. Grades: >98%. CAS No. 402567-16-2. Molecular formula: C27H27F2NO6. Mole weight: 499.5. | |
| Firocoxib | Firocoxib is a selective COX-2 inhibitor that can be used to control postoperative pain and inflammation associated with soft tissue and orthopedic surgery in dogs. Alternative Names: ML 1785713; ML-1785713; ML1785713; Equioxx; Previcox. CAS No. 189954-96-9. Molecular formula: C17H20O5S. Mole weight: 336.4. | |
| Flavokawain B | Flavokawain B is a chalcone isolated from Piper methysticum with strong antiangiogenic activity. Alternative Names: Flavokavain B; 4',6'-Dimethoxy-2'-hydroxychalcone; 2'-Hydroxy-4',6'-dimethoxychalcone; (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one. Grades: 98%. CAS No. 1775-97-9. Molecular formula: C17H16O4. Mole weight: 284.31. | |
| Flavopiridol Hydrochloride | Flavopiridol hydrochloride competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Alternative Names: NSC 649890 HCl; NSC649890 HCl; NSC-649890 HCl. Grades: >98%. CAS No. 131740-09-5. Molecular formula: C21H20ClNO5.HCl. Mole weight: 438.3. | |
| FLI-06 | FLI-06 is a Notch inhibitor that disrupts Notch trafficking and processing and reduces amyloid β secretion. It was shown to suppress proliferation and induce apoptosis and cell cycle arrest by targeting LSD1 and Notch pathway in esophageal squamous cell carcinoma cells. Alternative Names: FLI 06; cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate. Grades: >98%. CAS No. 313967-18-9. Molecular formula: C25H30N2O5. Mole weight: 438.524. | |
| FLLL32 | FLLL32, a novel curcumin analogue, is a potent STAT3 inhibitor. FLLL32 specifically reduced STAT3 phosphorylation at Tyr705 (pSTAT3) and induced apoptosis at micromolar amounts in human melanoma cell lines and primary melanoma cultures. Alternative Names: FLLL-32; BCP28141; (E)-3-(3,4-dimethoxyphenyl)-1-[1-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]cyclohexyl]prop-2-en-1-one. Grades: >98%. CAS No. 1226895-15-3. Molecular formula: C28H32O6. Mole weight: 464.558. | |
| Flonicamid | Flonicamid is a pyridinamide insecticide that is effective against a wide range of stinging mouthpart pests on crops, especially aphids. Alternative Names: 3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-; N-(Cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide; Aria; Aria (insecticide); Beleaf; Carbine; Carbine (insecticide); F 1785; F 1785-03-1; IKI 220; N-Cyanomethyl-4-(trifluoromethyl)nicotinamide; Teppeki; Ulala; Ulala DF. Grades: 95%. CAS No. 158062-67-0. Molecular formula: C9H6F3N3O. Mole weight: 229.16. | |
| Floribundone 1 | Floribundone 1 is a natural anthraquinone found in the herbs of Senna septemtrionalis. Alternative Names: 5,7'-Biphyscion. Grades: >98%. CAS No. 118555-84-3. Molecular formula: C32H22O10. Mole weight: 566.52. | |
| Fluconazole EP Impurity H | Fluconazole EP Impurity H is an impurity of Fluconazole, which is a triazole antifungal agent used in the treatment and prevention of superficial and systemic fungal infections. Alternative Names: (2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol; 1H-1,2,4-Triazole-1-ethanol, α-(bromomethyl)-α-(2,4-difluorophenyl)-; α-(Bromomethyl)-α-(2,4-difluorophenyl)-1H-1,2,4-triazole-1-ethanol; 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-bromopropan-2-ol; Fluconazole impurity H. Grades: ≥95%. CAS No. 150194-52-8. Molecular formula: C11H10BrF2N3O. Mole weight: 318.12. | |
| Fluorometholone Impurity A | An impurity in the synthesis of Fluorometholone, a glucocorticoid used for the treatment of eye conditions caused by inflammation. Alternative Names: 11β,17α-Dihydroxy-6α-methylpregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)-; 11beta,17alpha-Dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione; NSC 125051; Methyl Prednisolone Intermediates Deltamedrane; 11,17-Dihydroxy-6-methyl-(6α,11β)-pregna-1,4-diene-3,20-dione; Fluorometholone USP Related Ccompound A; Deltamedrane. Grades: > 95%. CAS No. 6870-94-6. Molecular formula: C22H30O4. Mole weight: 358.48. | |
| Fluphenazine-[d8] Dihydrochloride | Fluphenazine-[d8] Dihydrochloride is the labelled analogue of Fluphenazine. Fluphenazine is an antipsychotic medication. Alternative Names: 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazine-d8-ethanol Dihydrochloride; Fluphenazine-d8 Dihydrochloride. Grades: 98% by CP; 97% atom D. Molecular formula: C22H20D8Cl2F3N3OS. Mole weight: 518.5. | |
| Fluphenazine Decanoate Impurity 3 | Fluphenazine Decanoate Impurity 3 is one of Fluphenazine impurities. Fluphenazine is a phenothiazine antipsychotic, a dopaminergic antagonist and an antiviral agent. Alternative Names: Fluphenazine decanoate N-1-oxide; Decanoic acid, 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazinyl)ethyl ester, N-1-oxide; 2-(4-Oxo-4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-4lambda 5-piperazin-1-yl)ethyl decanoate; 4-(2-(decanoyloxy)ethyl)-1-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazine 1-oxide. Grades: > 98%. CAS No. 76013-31-5. Molecular formula: C32H44F3N3O3S. Mole weight: 607.77. | |
| (±)-Flurbiprofen-[d5] | (±)-Flurbiprofen-[d5] is the labelled analogue of (±)-Flurbiprofen, which could be used as an analgesic and anti-inflammatory agent. Alternative Names: (+/-)-Flurbiprofen D5; 2-Fluoro-α-methyl-[1,1'-biphenyl]-4-acetic-d5 Acid; 3-Fluoro-4-phenylhydratropic-d5 Acid; Flurbiprofen-d5; 2-Fluoro-α-methyl-4-diphenylacetic-d5 Acid; Adfeed-d5; Ansaid-d5; Flurofen-d5; Froben-d5; Stayban-d5; Zepolas-d5; DL-2-(2-Fluoro-4-biphenylyl)propionic-d5 Acid; DL-Flurbiprofen-d5; (±)-Flurbiprofen-d5 (phenyl-d5). Grades: 95% by HPLC; 98% atom D. CAS No. 215175-76-1. Molecular formula: C15H8D5FO2. Mole weight: 249.29. | |
| Fluroxypyr-[13C2] | Fluroxypyr-[13C2] is the labelled analogue of Fluroxypyr, which could be used as a herbicide as well as a synthetic auxin. Alternative Names: Fluroxypyr-13C2. Grades: >98% by HPLC; >98% atom 13C. Molecular formula: C5[13C]2H5Cl2FN2O3. Mole weight: 257.02. | |
| Fluticasone furoate | Fluticasone furoate is a synthetic corticosteroid derived from fluticasone, used for the treatment of seasonal allergic rhinitis. Uses: For treatment of seasonal allergic rhinitis. Alternative Names: Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-((2- furanylcarbonyl)oxy)-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6alpha,11beta,16alpha,17alpha)-; Gw 685698x; Unii-js86977wnv; Veramyst; (6α,11β,16α,17α)-6,9-Difluoro-17-[(2-furanylcarbony. Grades: > 95%. CAS No. 397864-44-7. Molecular formula: C27H29F3O6S. Mole weight: 538.59. | |
| FMK | FMK is a potent, highly specific and irreversible ribosomal s6 kinase (RSK) inhibitor that covalently modifies the C-terminal kinase domain of RSK. Its IC50 value is 15 nM. It could prevent the activation of the N-terminal kinase domain of RSK by the C-terminal kinase domain, but does not affect the activity of the N-terminal domain. It binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. It induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells. It is used to determine the role of RSK as a direct regulator of NHE1 phosphorylation and sarcolemmal NHE activity in this cell type, in response to 1-adrenergic stimulation. Uses: Fmk could prevent the activation of the n-terminal kinase domain of rsk by the c-terminal kinase domain, but does not affect the activity of the n-terminal domain. it is used to determine the role of rsk as a direct regulator of nhe1 phosphorylation and sarcolemmal nhe activity in this cell type, in response to 1-adrenergic stimulation. Alternative Names: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone;RSK2 kinase inhibitor. Grades: >98%. CAS No. 821794-92-7. Molecular formula: C18H19FN4O2. Mole weight: 342.37. | |
| Fmoc-AEG-OMe HCl | Fmoc-AEG-OMe HCl. CAS No. 172405-43-5. | |
| Fmoc-GGFG-OH | Fmoc-GGFG-OH is a protease cleavable linker used for the antibody-drug conjugate (ADC). Alternative Names: Fmoc-Gly-Gly-Phe-Gly-OH; (((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine. CAS No. 1817857-75-2. Molecular formula: C30H30N4O7. Mole weight: 558.60. | |
| Fmoc-Gly-Gly-Phe-OH | Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: (((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanine; (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9-trioxo-2-oxa-4,7,10-triazadodecan-12-oic acid. Grades: >98.0%. CAS No. 160036-44-2. Molecular formula: C28H27N3O6. Mole weight: 501.53. | |
| Fmoc-N-amido-PEG12-propionic acid | Fmoc-N-amido-PEG12-propionic acid is a PEG linker containing a protected amino group and a carboxylic acid. The carboxylic acid can be reacted with amino groups in the presence of activators. Alternative Names: Fmoc-N-amido-PEG12-acid; Fmoc-NH-PEG12-CH2CH2COOH; Fmoc-PEG12-propionic acid; (Fmoc-amino)-PEG12-C2-Carboxylic Acid; 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic acid; O-(N-Fmoc-2-aminoethyl)-O'-(2-carboxyethyl)-undecathyleneglycol; 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 1-(9H-Fluoren-9-ylmethyl)-5,8,11,14,17,20,23,26,29,32,35,38-dodecaoxa-2-azahentetracontanedioate. Grades: ≥99%. CAS No. 1952360-91-6. Molecular formula: C42H65NO16. Mole weight: 839.96. | |
| Fmoc-Ser(tBu)-OMe | Fmoc-Ser(tBu)-OMe. CAS No. 951324-28-0. | |
| Fmoc-Val-Ala-PAB-OH | Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: Fmoc-Val-Ala-PAB; (9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate. Grades: >98.0%(HPLC)(N). CAS No. 1394238-91-5. Molecular formula: C30H33N3O5. Mole weight: 515.60. | |
| Folic Acid EP Impurity D | Folic Acid EP Impurity D. CAS No. 119-24-4. | |
| Folic Acid EP Impurity E | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Alternative Names: 6-Pterinyl Folic Acid; N-[4-[Bis[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid. Grades: 95%. CAS No. 1391068-26-0. Molecular formula: C26H24N12O7. Mole weight: 616.55. | |
| foretinib | Potent inhibitor of MET, VEGFR2, Ron and AXL (IC50 values are 0.4, 0.9, 3 and 11 nM, respectively). Also potently inhibits Tie-2, Flt-1, Flt-3, Flt-4, KIT, PDGFRalpha and PDGFRbeta. Inhibits migration and invasion of B16F10 melanoma cells in vitro. Suppresses B16F10 tumor growth and metastasis in mice. Alternative Names: XL880; XL 880; XL-880; GSK1363089; GSK 1363089; GSK-1363089; GSK089; EXEL2880; Foretinib. CAS No. 849217-64-7. Molecular formula: C34H34F2N4O6. Mole weight: 632.665. | |
| Formoterol fumarate dihydrate | Formoterol fumarate dihydrate. CAS No. 183814-30-4. | |
| Formyl Ciprofloxacin | An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Alternative Names: Formylciprofloxacin (M4); Ciprofloxacin Formamide. Grades: > 95%. CAS No. 93594-39-9. Molecular formula: C18H18FN3O4. Mole weight: 359.36. | |
| Forsythoside I | Forsythoside I is a natural product isolated from forsythia suspense (thunb.) vahl, showing anti-inflammatory activities. Alternative Names: Isoforsythoside A. Grades: 0.98. CAS No. 1177581-50-8. Molecular formula: C29H36O15. Mole weight: 624.59. | |
| Fortunellin | Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Alternative Names: 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Acacetin 7-O-neohesperidoside. CAS No. 20633-93-6. Molecular formula: C28H32O14. Mole weight: 592.55. | |
| Fosaprepitant Benzyl Ester | Fosaprepitant Benzyl Ester. CAS No. 889852-02-2. | |
| Fosaprepitant-[d4] Dimeglumine | Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Alternative Names: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. | |
| Fosaprepitant dimeglumine | Fosaprepitant is a selective NK-1 receptor antahonist. It is a water-soluble phosphoryl prodrug for Aprepitant. Alternative Names: MK-0517; MK 0517; MK0517. Grades: >98%. CAS No. 265121-04-8. Molecular formula: C23H22F7N4O6P.2C7H17NO5. Mole weight: 1004.83. | |
| Fosbretabulin disodium | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Alternative Names: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
| Fosfluconazole | Fluconazole, a water-soluble phosphate prodrug of fluconazole, is a triazole antifungal agent that is effective against most Candida strains. Uses: 14-alpha demethylase inhibitors. Alternative Names: Procif; UK 292663; UK-292,663. Grades: > 95%. CAS No. 194798-83-9. Molecular formula: C13H13F2N6O4P. Mole weight: 386.26. | |
| Fosinoprilat | Fosinoprilat is a metabolite of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Alternative Names: Fosinopril sodium EP Impurity A; Fosinopril Related Compound A; Fosinopril diacid; Fosfenopril; Fosinoprilic acid. Grades: > 95%. CAS No. 95399-71-6. Molecular formula: C23H34NO5P. Mole weight: 435.50. | |
| FOY 251 | FOY 251 is a metabolite of camostat mesilate, and a proteinase inhibitor. Alternative Names: Foy 251;71079-09-9;4-(4-Guanidinobenzoyloxy)phenylacetic acid;FOY-251 mesylate;FOY251;4-GBCE (methanesulfonate);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt;2-[4-[4-(diaminomethylideneamino)benzoyl]oxyphenyl]acetic acid;methanesulfonic acid;CHEMBL433135;FOY-251 mesylate?;4-[[4-[(AMINOIMINOMETHYL)AMINO]BENZOYL]OXY]-BENZENEACETIC ACID MONOMETHANESULFONATE;SCHEMBL1649708;SCHEMBL11417275;DTXSID20991365;EX-A5589;HY-19727A;MFCD09842546;s3511;AKOS030614588;CS-0016501;EN300-7455534;4-(4-Guanidinobenzoyloxy)-phenylacetic acid x Methanesulfonic acid;2-[4-(4-carbamimidamidobenzoyloxy)phenyl]acetic acid; methanesulfonic acid;[4-(4-CARBAMIMIDAMIDOBENZOYLOXY)PHENYL]ACETIC ACID; METHANESULFONIC ACID;{4-[(4-Carbamimidamidobenzoyl)oxy]phenyl}acetic acid--methanesulfonic acid (1/1);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid compound with methanesulfonic acid (1:1);2-(4-((4-guanidinobenzoyl)oxy)phenyl)acetic acid--methanesulfonic acid (1/1);Benzeneacetic acid, 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, monomethanesulfonate. CAS No. 71079-09-9. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09. | |
| FPFS-1169 HCl | FPFS-1169 HCl. CAS No. 265130-22-1. | |
| Freselestat | Freselestat is a high affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM) with >100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Freselestat can be used as treatment for neutrophil-predominant inflammatory lung diseases. Alternative Names: 2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)-N-[1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-3-methyl-1-oxobutan-2-yl]acetamide; ONO6818; ONO 6818; ONO-6818. Grades: 95%. CAS No. 208848-19-5. Molecular formula: C23H28N6O4. Mole weight: 452.51. | |
| FSEN1 | FSEN1. CAS No. 862808-01-3. | |
| FSL-1 TFA salt | FSL-1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL-1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Alternative Names: FSL 1 TFA salt; FSL1 TFA salt; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-, 2,2,2-trifluoroacetic acid; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine 2,2,2-trifluoroacetic acid; FSL-1 lipoprotein, synthetic TFA salt; Fibroblast-stimulating lipopeptide-1 TFA salt; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH TFA. Grades: ≥95%. Molecular formula: C86H141F3N14O20S. Mole weight: 1780.18. | |
| FT011 | FT011. CAS No. 1001288-58-9. | |
| Fulacimstat | Fulacimstat is a chymase inhibitor with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively. Uses: Enzyme inhibitors. Alternative Names: BAY1142524. CAS No. 1488354-15-9. Molecular formula: C23H16F3N3O6. Mole weight: 487.4. | |
| Fulvestrant Beta-Isomer | Fulvestrant Beta-Isomer, a drug utilized in the management of metastatic breast cancer associated with hormone receptor positivity, acts as a selective estrogen receptor down-regulator that impedes breast cancer cell growth by binding to and disintegrating estrogen receptors. Its modus operandi is to lower the expression of estrogen receptors. Alternative Names: (7β,17β)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol; Fulvestrant EP Impurity A; 7β-fulvestrant; 7beta-fulvestrant; Fulvestrant β-isomer. Grades: > 95%. CAS No. 407577-53-1. Molecular formula: C32H47F5O3S. Mole weight: 606.79. | |
| Fulvestrant EP Impurity D | Fulvestrant EP Impurity D is an impurity of Fulvestrant, which is an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Alternative Names: 7,7'-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol]; Fulvestrant Sterol Dimer (Mixture of Diastereomers). Grades: 95%. CAS No. 2483797-59-5. Molecular formula: C45H64O4. Mole weight: 668.99. | |
| Fulvestrant Extended | Fulvestrant Extended is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Alternative Names: (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol. Grades: > 95%. Molecular formula: C41H65F5O4S. Mole weight: 781.09. | |
| Fumagillol | Fumagillol is a precursor of Fumagillin, which is an antimicrobial agent used for the treatment of microsporidiosis. Fumagillol also exhibits anti-infective and antiangiogenic effects. Alternative Names: 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-; (3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]octan-6-ol; 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, (3R,4S,5S,6R)-; 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, [3R-[3α,4α(2R*,3R*),5β,6β]]-; (-)-Fumagillol; FOS 37; Gelcohol. Grades: 90%. CAS No. 108102-51-8. Molecular formula: C16H26O4. Mole weight: 282.38. | |
| Fumaryl diketopiperazine | Fumaryl diketopiperazine. CAS No. 176738-91-3. | |
| Furaltadone-[d5] | Furaltadone-[d5] is the labelled analogue of Furaltadone, which is a nitrofuran antibacterial drug for the treatment of coccidiosis. Alternative Names: Furaltadone-D5; 5-morpholin-4-ylmethyl-3-(5-nitrofuran-2-ylmethyleneamino)-oxazolidin-2-one-D5; 5-(4-Morpholinylmethyl-d2)-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone-4,4,5-d3; Nitrofurmethone-d5; Nitrofurmeton-d5; Furazolin-d5; Furmethanol-d5; Ibifur-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 1015855-64-7. Molecular formula: C13H11D5N4O6. Mole weight: 329.32. | |
| Furazolidone-[d4] | Furazolidone-[d4] is the labelled analogue of Furazolidone, which is a nitrofuran derivative with antiprotozoal and antibacterial activity. It is used to treat anorexia and antagonism of thiamin utilization in poultry. Alternative Names: Furazolidone-D4; 3-[(5-Nitrofuran-2-ylmethylene)-amino]-oxazolidin-2-one-D4; 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone-d4; 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone-d4; Diafuron-d4; Furaxon-d4; Furazol-d4; Furazolidon-d4; Giardil-d4; Giarlam-d4; Medaron-d4; Ortazol-d4; Puradin-d4; Roptazol-d4; Tikofuran-d4; Topazone-d4; Trifurox-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 1217222-76-8. Molecular formula: C8H3D4N3O5. Mole weight: 229.18. | |
| Furfuryl acrylate | Furfuryl acrylate. Alternative Names: furan-2-ylmethyl acrylate. Grades: 95%. CAS No. 10525-17-4. Molecular formula: C8H8O3. Mole weight: 152.15. | |
| Furosemide EP Impurity C | Furosemide Impurity C is a metabolite of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Alternative Names: Furosemide Related Compound B; 4-Chloro-5-sulfamoylanthranilic acid; 4-Chloro-5-sulfamylanthranilic acid; Desfurylmethylfurosemide; Saluamine; 4-Chloro-5-sulfamoyl-anthranilic Acid. Grades: > 95%. CAS No. 3086-91-7. Molecular formula: C7H7ClN2O4S. Mole weight: 250.66. | |
| Futibatinib | Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Alternative Names: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. Grades: ≥ 98 %. CAS No. 1448169-71-8. Molecular formula: C22H22N6O3. Mole weight: 418.45. | |
| Fuziline | Fuziline is extracted from the roots of Aconitum carmichaeli Debx. Alternative Names: Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- , (1alpha,6alpha,14alpha,15alpha,16beta)-; 15-Epinagarine; 15-Hydroxyneoline; Senbusine C. Grades: >98%. CAS No. 80665-72-1. Molecular formula: C24H39NO7. Mole weight: 453.6. | |
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