BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| GSK-LSD1 2HCl | GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). Alternative Names: GSK LSD1 2HCl; GSK-LSD1 Dihydrochloride. Grades: >98%. CAS No. 1431368-48-7. Molecular formula: C14H22Cl2N2. Mole weight: 289.24. |  |
| GTS-21 dihydrochloride | GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent. Alternative Names: GTS-21; GTS 21; GTS21; DMBX-A. Grades: 98%. CAS No. 156223-05-1. Molecular formula: C19H20N2O2.2HCl. Mole weight: 381.30. | |
| Guajadial B | Guajadial B isolated from the herbs of Psidium guajava. Alternative Names: Benzo[b]cycloundeca[e]pyran-2,4-dicarboxaldehyde, 5a,6,9,10,13,14,14a,15-octahydro-1,3-dihydroxy-5a,9,9,12-tetramethyl-15-phenyl-, (5aR,7E,11E,14aS,15R)-rel-. Grades: 0.97. CAS No. 1414455-03-0. Molecular formula: C30H34O5. Mole weight: 474.6. | |
| Guajadial D | Guajadial D is a sesquiterpenoid-based meroterpenoid isolated from the leaves of Psidium guajava. Guajadial D has potential anticancer effects. Alternative Names: (1S,4R,4'S,4aR,7S)-5',7'-dihydroxy-4-methyl-4'-phenyl-1-propan-2-ylspiro[2,3,4,4a,5,6-hexahydro-1H-naphthalene-7,2'-3,4-dihydrochromene]-6',8'-dicarbaldehyde. CAS No. 1529775-04-9. Molecular formula: C30H34O5. Mole weight: 474.597. | |
| Guajadial E | Guajadial E is a sesquiterpenoid-based meroterpenoid isolated from the leaves of Psidium guajava. Guajadial E has potential anticancer effects. Alternative Names: (5aS,7S,10R,10aR,11aR,12S)-1,3-dihydroxy-5a,10-dimethyl-12-phenyl-7-propan-2-yl-7,8,9,10,10a,11,11a,12-octahydrobenzo[b]xanthene-2,4-dicarbaldehyde. Grades: 95.0%. CAS No. 1529775-06-1. Molecular formula: C30H34O5. Mole weight: 474.597. | |
| Guajadial F | Guajadial F is a sesquiterpenoid-based meroterpenoid isolated from the leaves of Psidium guajava. Guajadial F has potential anticancer effects. Biochemical topoisomerase I (Top1) assay revealed that guajadial F acted as a Top1 catalytic inhibitor and delayed Top1 poison-mediated DNA damage. Alternative Names: (5aS,7S,10R,10aR,11aR,12R)-1,3-dihydroxy-5a,10-dimethyl-12-phenyl-7-propan-2-yl-7,8,9,10,10a,11,11a,12-octahydrobenzo[b]xanthene-2,4-dicarbaldehyde. Grades: 96.0%. CAS No. 1529775-08-3. Molecular formula: C30H34O5. Mole weight: 474.597. | |
| Guanfacine hydrochloride | Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It lowers both systolic and diastolic blood pressure. Alternative Names: BS 100-141; Tenex; Estulic; Guanfacine HCl; N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride; N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride; N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1). Grades: 95%. CAS No. 29110-48-3. Molecular formula: C9H10Cl3N3O. Mole weight: 282.56. | |
| GW0742 | GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Alternative Names: GW0742; GW-0742; GW 0742; GW0742X; GW-0742X; GW 0742X; GW610742; GW-610742; GW 610742. Grades: >98%. CAS No. 317318-84-6. Molecular formula: C21H17F4NO3S2. Mole weight: 471.49. | |
| GW1929 | A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Alternative Names: GW 1929; GW-1929. Grades: >98%. CAS No. 196808-24-9. Molecular formula: C30H29N3O4. Mole weight: 495.57. | |
| GW 441756 | GW 441756 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor (IC50 = 2 nM), reducing cell proliferation and potentiates the effects of chemotherapeutic agents. Uses: A specific tropomyosin-related kinase a (trka) inhibitor. Alternative Names: GW-441756; GW 441756; GW441756. 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one;(3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one. Grades: ≥98%. CAS No. 504433-23-2. Molecular formula: C17H13N3O. Mole weight: 275.30. | |
| GW4869 | GW4869 is a cell-permeable, specific and non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM). Alternative Names: (E)-3-[4-[(E)-3-[4-(4,5-dihydro-1H-imidazol-2-yl)anilino]-3-oxoprop-1-enyl]phenyl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]prop-2-enamide;dihydrochloride; GW 4869; GW-4869. CAS No. 6823-69-4. Molecular formula: C30H30Cl2N6O2. Mole weight: 577.5. | |
| GW 627368X | GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity (Ki values of 100 nM and 158 nM, respectively). Uses: A potent and selective competitive antagonist. Alternative Names: GW627368X; GW 627368X; GW-627368X; GW627368; GW 627368; GW-627368. N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide; 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide. Grades: ≥96%. CAS No. 439288-66-1. Molecular formula: C30H28N2O6S. Mole weight: 544.62. | |
| GW-870086 | GW-870086 is a glucocorticoid receptor agonist with a pIC50 of 10.1 in A549 cells expressing NF-κB. It can be used as an anti-inflammatory agent. Alternative Names: GW-870086; GW-870086X; 870086; GW870086; GW870086X; GW 870086; GW 870086X. CAS No. 827319-43-7. Molecular formula: C31H39F2NO6. Mole weight: 559.651. | |
| GW9508 | GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, and stimulates insulin secretion in a glucose-sensitive manner. GW9508 is commonly used in the treatment of type 2 diabetes. Alternative Names: GW9508; GW-9508; GW 9508; 3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid. Grades: > 98%. CAS No. 885101-89-3. Molecular formula: C22H21NO3. Mole weight: 347.414. | |
| GX-674 | GX-674 is a Nav1.7 antagonist in the aryl sulfonamide class with higher selectivity for Nav1.7 (IC50= 0.1nM) over other Nav subtypes. Nav1.7 is commonly expressed in olfactory epithelium, sympathetic ganglion, and dorsal root ganglion sensory neurons. GX-674 has the potential to alleviate extreme pains. Alternative Names: GX-674; GX674;GX 674; 4-(2-(2-Amino-1H-benzo[d]imidazol-5-yl)-4-chlorophenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide. CAS No. 1432913-36-4. Molecular formula: C21H13ClF2N6O3S2. Mole weight: 534.94. | |
| Gyrophoric acid | Gyrophoric acid isolated from the herbs of Parmelia tinctorum Despr. Uses: Anti-tumor; anti-cancer; antibacterial; antimicrobial; anti-proliferative / cytotoxic effect. Alternative Names: triorsellinic acid; 4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid. Grades: 0.98. CAS No. 548-89-0. Molecular formula: C24H20O10. Mole weight: 468.4. | |
| H1-7 acetate salt | H1-7 acetate salt. | |
| H3B-6527 | H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity. Alternative Names: N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527. CAS No. 1702259-66-2. Molecular formula: C29H34Cl2N8O4. Mole weight: 629.543. | |
| Haginin A | Haginin A is a natural compound isolated from the aerial parts of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity and mushroom tyrosinase inhibitory activity. Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of tyrosinase and TRP-1 production. Alternative Names: 7,4'-Dihydroxy-2',3'-dimethoxyisoflavene. Grades: 97%. CAS No. 74174-29-1. Molecular formula: C17H16O5. Mole weight: 300.31. | |
| HAIYPRH (hydrochloride) | HAIYPRH (hydrochloride). | |
| Halofuginone-[13C6] Hydrobromide | Halofuginone-[13C6] Hydrobromide is the labelled derivative of Halofuginone. Halofuginone is a coccidiostat used in veterinary medicine. High affinity competitive prolyl-tRNA synthetase inhibitor. Blocks expression of MMP2. Inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice. Alternative Names: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone-13C6 Hydrobromide; trans-(+/-)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone-13C6 Monohydrobromide. Grades: 95% by CP; 98% atom 13C. Molecular formula: C10[13C]6H18Br2ClN3O3. Mole weight: 501.55. | |
| Harmine Hydrochloride | Harmine is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as "yage" or "ayahuasca"). Alternative Names: Harmine monohydrochloride; Telepathine (hydrochloride); 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, monohydrochloride. Grades: 98%. CAS No. 343-27-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| H-ASP-ASP-OH TFA | H-ASP-ASP-OH TFA. | |
| Hautriwaic acid | Hautriwaic acid is a natural diterpenoid found in the herbs of Dodonaea viscosa. Hautriwaic acid may have hepatoprotective activity. Uses: Hepatoprotective. Alternative Names: (4aR)-5β-[2-(3-Furyl)ethyl]-5,6α-dimethyl-8aα-(hydroxymethyl)-3,4,4aβ,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid. Grades: >97%. CAS No. 18411-75-1. Molecular formula: C20H28O4. Mole weight: 332.44. | |
| Hebeirubescensin H | Hebeirubescensin H is a natural diterpenoid compound found in several plants. Alternative Names: (1alpha,6beta,7alpha,14R,20R)-7,20-Epoxy-1,6,7,14,20-pentahydroxykaur-16-en-15-one. Grades: >95%. CAS No. 887333-30-4. Molecular formula: C20H28O7. Mole weight: 380.43. | |
| Hederacolchiside A1 | Hederacolchiside A1, an awe-inspiring compound derived from the natural reserves of Pulsatilla chinensis. Graced with the remarkable ability to instigate programmed cellular death and differentiation, it serves as a beacon of hope in the realm of acute promyelocytic leukemia therapy. Grades: >98%. CAS No. 106577-39-3. Molecular formula: C47H76O16. | |
| Hederacolchiside E | Hederacolchiside E is extracted from Pulsatilla chinensis (Bunge) Regel. Alternative Names: Hederacolchiside E; 33783-82-3; Hederacholchiside E; CHEMBL4165893; DTXSID201316054; AKOS040760443; HY-107311; CS-0027959; D84974. Grades: >98%. CAS No. 33783-82-3. Molecular formula: C65H106O30. Mole weight: 1367.5. | |
| Hederagenin - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside | Hederagenin - 3-O-β-D- Galactosyl( 1→3)-β-D-glucosyl( 1→3)-α-L-rhamnosyl(1→2)-α-L-arabinoside is a triterpenoids isolated from pulsatilla chinensis BungeRegel. Pulsatilla chinensis (Bunge) Regel is a botanical with a long history of medical use in China, which exhibits "blood-cooling" and detoxification activities. The roots of P. chinensis have been widely used in the traditional Chinese medicine for adjunctive treatment of intestinal amebiasis, malaria, vaginal trichomoniasis, bacterial infections and malignant tumor. Grades: > 98%. Molecular formula: C53H86O22. Mole weight: 1075.24. | |
| Hederagonic acid | Hederagonic acid is a natural triterpenoid found in the root of Pulsatilla chinensis. Alternative Names: 23-Hydroxy-3-oxoolean-12-en-28-oic acid. Grades: >97%. CAS No. 466-01-3. Molecular formula: C30H46O4. Mole weight: 470.7. | |
| Hedycoronen A | Hedycoronen A is an inhibitor of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, exhibiting potential anti-inflammatory activity. Alternative Names: 15-Methoxylabda-8(17),11E,13-trien-16,15-olide. Grades: >96%. CAS No. 1383441-73-3. Molecular formula: C21H30O3. Mole weight: 330.5. | |
| Heliangin | Heliangin isolated from the herbs of Helianthus tuberosus L. Uses: Cytotoxic. Alternative Names: (E)-2-Methyl-2-butenoic acid [(1aR,3S,4Z,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester. Grades: > 95%. CAS No. 13323-48-3. Molecular formula: C20H26O6. Mole weight: 362.4. | |
| Helichrysetin | Helichrysetin is a natural chalcone isolated from the fruits of Alpinia katsumadai Hayata, it exhibits the activity of anticancer and has mild anti-HIV-1 PR activity. Uses: Anticancer. Alternative Names: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-prop en-1-one. Grades: >98%. CAS No. 62014-87-3. Molecular formula: C16H14O5. Mole weight: 286.3. | |
| Hellebrigenin | Hellebrigenin is an anticancer agent that induces DNA damage, mitochondria collapse, cell cycle arrest and apoptosis. Alternative Names: Bufotalidin; (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde. CAS No. 465-90-7. Molecular formula: C24H32O6. Mole weight: 416.514. | |
| Hemokinin 1, human TFA | Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. It can produce an opioid-independent analgesia. Alternative Names: Hemokinin 1 (human) (trifluoroacetate salt); L-threonylglycyl-L-lysyl-L-alanyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide, trifluoroacetate salt. Grades: 95%. Molecular formula: C56H85F3N14O16S. Mole weight: 1299.42. | |
| Heptadecanedioic acid | Heptadecanedioic acid (CAS# 2424-90-0 ) is a useful research chemical. Alternative Names: 1,15-PENTADECANEDICARBOXYLIC ACID; HEPTADECANEDIOIC ACID; heptadecandionic acid; 1,17-Heptadecanedioic acid. Grades: 95 %. CAS No. 2424-90-0. Molecular formula: C17H32O4. Mole weight: 300.43. | |
| Heraclenin | Heraclenin is isolated from the fruits of Citrus aurantium L. It induces apoptosis in Jurkat leukemia cells. Uses: Anti-inflammatory. Grades: 98.5%. CAS No. 2880-49-1. Molecular formula: C16H14O5. Mole weight: 286.3. | |
| Heraclenol | Heraclenol isolated from the herbs of Heracleum repula Franch inhibits the proliferation of melanoma cells and cell cycle. Alternative Names: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-. Grades: 98.5%. CAS No. 31575-93-6. Molecular formula: C16H16O6. Mole weight: 304.3. | |
| (-)-Heraclenol | (-)-Heraclenol is a natural coumarin compound found in several plants. Alternative Names: (-)-9-[(S)-2,3-Dihydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one; 9-[(S)-2,3-Dihydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one. Grades: >95%. CAS No. 139079-42-8. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| Heveaflavone | Heveaflavone is a natural flavonoid found in the herbs of Selaginella tamariscina (P. Beauv.) Spring, it has anti-proliferation effect. Uses: Anti-proliferation. Alternative Names: 2-(4-Methoxyphenyl)-5-hydroxy-7-methoxy-8-[2-hydroxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one. Grades: >97%. CAS No. 23132-13-0. Molecular formula: C33H24O10. Mole weight: 580.6. | |
| Hexadecanedioic Acid | Hexadecanedioic Acid is a useful research intermediate for the studies of blood pressure regulations in humans. Hexadecandedioate works in collaboration with SLCO1B1 as a potential therapy for statin. Uses: This product is suitable for scientific research. Alternative Names: Thapsic acid; 1,16-Hexadecanedioic acid; 1,14-Tetradecanedicarboxylic acid. Grades: 95%. CAS No. 505-54-4. Molecular formula: C16H30O4. Mole weight: 286.41. | |
| Hexadecyl propionate | Hexadecyl propionate, a synthetic compound with broad applicability, is extensively utilized in cosmetic products for its emollient effects. This molecular agent functions to both soften and soothe the skin while simultaneously shielding it from environmental threats, a remarkable feat. Furthermore, this versatile compound has found applications within various pharmaceutical formulations, particularly those designed for treating a myriad of dermatological disorders, such as eczema and psoriasis. Alternative Names: 1-Hexadecanol, propanoate; Propionic acid hexadecyl ester; NSC 53827; NSC 67972; 1-Hexadecanol, 1-propanoate. Grades: ≥95%. CAS No. 6221-96-1. Molecular formula: C19H38O2. Mole weight: 298.50. | |
| Hexa-His HCl | Hexa-His, consisting of 6 His residues in a row, called His-Tag, is used as a metal binding site for the recombinant protein. Alternative Names: 6X His Tag HCl. Grades: 95%. Molecular formula: C36H45ClN18O7. Mole weight: 877.33. | |
| Hexa-His TFA | Hexa-His, consisting of 6 His residues in a row, called His-Tag, is used as a metal binding site for the recombinant protein. Alternative Names: 6X His Tag TFA. Grades: 95%. CAS No. 1456728-20-3. Molecular formula: C38H45F3N18O9. Mole weight: 954.87. | |
| Hexahydrocurcumin | Hexahydrocurcumin is extracted from the rhizomes of Curcuma longa L. Hexahydrocurcumin shows cytotoxic effect. Uses: A natural compound which posesses anticancer and anti-inflammatory activities. Alternative Names: (RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone; 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone. Grades: 98%. CAS No. 36062-05-2. Molecular formula: C21H26O6. Mole weight: 374.43. | |
| Hexapeptide-11 (acetate) | Hexapeptide-11, a synthetic peptide widely used as an anti-aging ingredient in cosmetics, reduces the appearance of fine lines and wrinkles and is an excellent addition to a variety of skin care and anti-aging products. Hexapeptide-11 regulates collagen levels, improves skin elasticity, increases skin firmness, supplements polyligand proteoglycan deficiency in aging skin, improves epidermal adhesion, and makes skin look more shiny and even. Alternative Names: L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline, acetic acid. Grades: 98%. Molecular formula: C38H52N6O9. Mole weight: 736.86. | |
| Hexyl benzoate | Hexyl benzoate is used as a fragrance for soaps, perfumes, and creams. Alternative Names: Benzoic acid, hexyl ester; n-Hexylbenzoate; Benzoic acid n-hexyl ester; 1-Hexyl benzoate. Grades: 98+%. CAS No. 6789-88-4. Molecular formula: C13H18O2. Mole weight: 206.28. | |
| HG-9-91-01 | HG-9-91-01,a small molecule inhibitor that targets specificly salt-inducible kinase (SIKs) IC50: SIK1=0.92 nM; SIK2=6.6 nM; SIK3=9.6 nM. Alternative Names: 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]ureaHG-9-91-01; HG-9-91-01; HG 9-91-01; HG9-91-01; HG99101; HG-99101; HG 99101;GTPL8049SCHEMBL15271960BDBM192712CS-1749HG-9-91-01 (1)1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiper. CAS No. 1456858-58-4. Molecular formula: C32H37N7O3. Mole weight: 567.68. | |
| H-HIS-HIS-OH TFA | H-HIS-HIS-OH TFA. | |
| HINOKIFLAVONE | Hinokiflavone is isolated from the leaves of Platycladus orientalis. It has inhibition of MMP-9. Uses: Significant cytotoxicity. Alternative Names: 6-[4-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 2-(4-Hydroxyphenyl)-5,7-dihydroxy-6-[4-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-4H-1-benzopyran-4-one. Grades: 97%. CAS No. 19202-36-9. Molecular formula: C30H18O10. Mole weight: 538.5. | |
| Hirsuteine | Hirsuteine is an alkaloid isolated from Uncaria rhynchophylla. Hirsuteine exhibits antagonistic effects on nicotinic receptors in vitro. Alternative Names: Methyl 2-(3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate. Grades: 98.0%. CAS No. 35467-43-7. Molecular formula: C22H26N2O3. Mole weight: 366.461. | |
| Hirsutenone | Hirsutenone is isolated from the leaves of Alnus nepalensis. It may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases. Uses: Hirsutenone exhibits many biological activities, including anti-inflammatory, anti-tumor promoting and anti-atopic dermatitis effects. Alternative Names: Dehydrohirsutanonol; 1,7-Bis-(3,4-dihydroxyphenyl)-4-hepten-3-one; (4E)-1,7-Bis(3,4-dihydroxyphenyl)-4-hepten-3-one. Grades: 95%. CAS No. 41137-87-5. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Hirsutine | Hirsutine is an alkaloid isolated from Uncaria rhynchophylla, showing anti-cancer activity. Alternative Names: Hirsutine;7729-23-9;UNII-W596OF93C7;W596OF93C7;methyl (E)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate;CHEMBL327134;(E)-16,17-Didehydro-17-methoxy-17,18-seco-3-beta-yohimban-16-carboxylic acid methyl ester;Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3-beta,16E)-;17,18-Seco-3-beta-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-;hirsutine, (3beta,16E)-isomer;DTXSID801045724;HY-N2193;BDBM50396011;AKOS040760133;Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3.beta.,16E)-;17,18-Seco-3.beta.-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-;AC-34492;DA-54004;MS-25915;CS-0019501;C16972;Q15614855;17,18-SECO-3beta-YOHIMBAN-16-CARBOXYLIC ACID, 16,17-DIDEHYDRO-17-METHOXY-, METHYL ESTER, (E)-;76376-57-3;CORYNAN-16-CARBOXYLIC ACID, 16,17-DIDEHYDRO-17-METHOXY-, METHYL ESTER, (3beta,16E)-;INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID, 3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-.ALPHA.-(METHOXYMETHYLENE)-, METHYL ESTER, (.ALPHA.E,2S,3R,12BR)-;INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID, 3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-alpha-(METHOXYMETHYLENE)-, METHYL ESTER, (alphaE,2S,3R,12BR)-. Grades: 98%. CAS No. 7729-23-9. Molecular formula: C28H30O2. Mole weight: 398.5. | |
| Hispidanin B | Hispidanin B is extracted from the rhizomes of Isodon hispida. It displays cytotoxicity against tumor cell lines SMMC7721, K562 and SGC7901, which IC50 values are 9.8, 13.7 and 10.7uM respectively. Alternative Names: Hispidanin B; 1616080-84-2; 4-[(4-acetyloxy-2',6,6,9a-tetramethyl-2-oxospiro[4,5,5a,7,8,9-hexahydronaphtho[2,1-e][1]benzofuran-3,6'-cyclohex-2-ene]-1'-yl)methyl]-8,8-dimethyl-3-methylidene-2,4,5,6,7,8a-hexahydro-1H-naphthalene-4a-carboxylic acid; B0005-267531. Grades: 95.0%. CAS No. 1616080-84-2. Molecular formula: C42H56O6. Mole weight: 656.89. | |
| Hispidin | Hispidin is a polyphenol isolated from Pteris ensiformis. It exhibits antioxidant, anti-inflammatory, and cytoprotective properties. Hispidin is also a precursor of fungal luciferin, emits bioluminenscence in the luminous fungal fruiting body. Alternative Names: 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone; 6-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one. Grades: ≥95%. CAS No. 555-55-5. Molecular formula: C13H10O5. Mole weight: 246.2. | |
| HIV-1-TAT(48-60) TFA | HIV-1-TAT(48-60) TFA. | |
| HIV-1 TAT protein (47-57) TFA | HIV-1 TAT protein (47-57) TFA. | |
| HMN-214 | HMN-214 is an oral prodrug of HMN-176, a stilbene derivative that interferes with the subcellular spatial location of polo-like kinase-1, a serine / threonine kinase that regulates critical mitotic events. Alternative Names: HMN-214; HMN 214. CAS No. 173529-46-9. Molecular formula: C22H20N2O5S. Mole weight: 424.471. | |
| Holothurin A2 | Holothurin A2. Grades: 95%. CAS No. 75410-53-6. Molecular formula: C54H88NaO26S+. Mole weight: 1208.32000. | |
| Homatropine methylbromide | Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. Alternative Names: Homatropine Methylbromide; Omatropina metilbromuro; 8-Methylhomatropinium bromide; Homatropine methobromide; Homatropine methyl bromide; AC1L1MZP; Methylhomatropine. Grades: >98%. CAS No. 80-49-9. Molecular formula: C17H24BrNO3. Mole weight: 370.28. | |
| Homocysteine Methyltransferase, Recombinant | Homocysteine Methyltransferase, Recombinant is a key enzyme in new biocatalyst technology. Alternative Names: Homocysteine S-methyltransferase; S-adenosylmethionine homocysteine transmethylase. CAS No. 9012-40-2. | |
| (±)-Homoeriodictyol | (±)-Homoeriodictyol is a natural compound isolated from the herbs of Taxillus sutchuenensis. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-; 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; (±)-5,7,4'-Trihydroxy-3'-methoxyflavanone; Homoeriodictyol (+/-)-; (+/-)-Homoeriodictyol. Grades: ≥95%. CAS No. 69097-98-9. Molecular formula: C16H14O6. Mole weight: 302.28. | |
| Homoplantaginin | Homoplantaginin is a flavonoid glycoside found in Scoparia dulcis. Homoplantaginin ameliorates endothelial insulin resistance by inhibiting inflammation and modulating cell signalling via the IKKβ/IRS-1 / pAkt / peNOS pathway, suggesting it may be used for the prevention and treatment of endothelial dysfunction associated with insulin resistance. Alternative Names: 5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside. Grades: >98%. CAS No. 17680-84-1. Molecular formula: C22H22O11. Mole weight: 462.4. | |
| Homovanillic Acid-[d3] | Homovanillic Acid-[d3] is an isotopically-labeled version of Homovanillic Acid (HVA). This important dopamine metabolite is predominantly found in human urine and is a valuable biochemical research tool for investigating the mechanisms underlying neuropsychiatric and neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and schizophrenia. Its use in these studies is useful, given the marked alterations in dopamine metabolism and function that are observed in these conditions. Uses: A neuroendocrine tumor marker. a labelled metabolite of dihydroxyphenylacetic acid (dopac) by catechol o-methyltransferase. Alternative Names: Homovanillic Acid D3. Grades: 95% atom D. CAS No. 74495-71-9. Molecular formula: C9H7D3O4. Mole weight: 185.19. | |
| HO-PEG24-OH | HO-PEG24-OH. Alternative Names: HO-PEG24-OH; 2243942-52-9; PEG25; OH-PEG24-OH; 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-TRICOSAOXAHENHEPTACONTANE-1,71-DIOL; MFCD28976705; SCHEMBL2582270; DTXSID501025080. Grades: >95%. Molecular formula: C48H98O25. Mole weight: 1075.28. | |
| HS-173 | HS-173 is a potent and selective PI3Kα inhibitor displaying anticancer activity. HS-173 was shown to induce apoptosis via arresting the cell cycle at the G2/M phase. It also decreases angiogenesis induced by VEGF. Alternative Names: Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate; HS173; HS 173; HS-173. Grades: 98%. CAS No. 1276110-06-5. Molecular formula: C21H18N4O4S. Mole weight: 422.459. | |
| hsa-miR-146a-5p antagomir | hsa-miR-146a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo. Grades: ≥90% by HPLC. Mole weight: 7311.74. | |
| hsa-miR-146a-5p Inhibitor | hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Grades: ≥90% by HPLC. Mole weight: 6592.37. | |
| HSP990 | HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (HSP90) with potential antineoplastic activity. HSP990 binds to and inhibits the activity of Hsp90, which may result in the proteasomal degradation of oncogenic client proteins, including HER2/ERBB2, and the inhibition of tumor cell proliferation. HSP90, upregulated in a variety of tumor cells, is a molecular chaperone that plays a key role in the conformational maturation, stability and function of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation and/or immune responses. Alternative Names: NVP-HSP990; NVP HSP990; NVPHSP990; HSP 990; HSP-990. Grades: >98%. CAS No. 934343-74-5. Molecular formula: C20H18FN5O2. Mole weight: 379.39. | |
| HTH-01-015 | HTH-01-015 is a potent and selective inhibitor of NUAK1 with IC50 of 100 nM, does not significantly inhibit NUAK2 (IC50 of >10 μM). Alternative Names: HTH-01-015; HTH01-015; HTH 01-015; HTH-01015; HTH01015; HTH 01015. Grades: >98%. CAS No. 1613724-42-7. Molecular formula: C26H28N8O. Mole weight: 468.55. | |
| Hulupinic acid | Hulupinic acid is a natural compound which can be isolated from Humulus lupulus. Alternative Names: 2,2-Bis(3-methylbut-2-enyl)-4,5-bis(oxidanyl)cyclopent-4-ene-1,3-dione; 4,5-Dihydroxy-2,2-bis(3-methyl-2-butenyl)-4-cyclopentene-1,3-dione. Grades: 98%. CAS No. 1891-42-5. Molecular formula: C15H20O4. Mole weight: 264.32. | |
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