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Ethyl(2-methylpropyl)amine hydrochloride
Ethyl(2-methylpropyl)amine hydrochloride, a pharmaceutical intermediate, is a white crystalline powder with versatile applications in the synthesis of organic compounds. It serves as an essential building block in the production of amides and esters, consequently contributing to the development of drugs for debilitating conditions like Alzheimer's and Parkinson's disease. Its proficiency in aiding therapeutic breakthroughs and enabling the advancement of the medical industry underscores its significance. Alternative Names: N-Ethyl-N-isobutylamine hydrochloride; Ethylisobutylamine hydrochloride; N-Ethyl-2-methyl-1-propanamine hydrochloride (1:1); 1-Propanamine, N-ethyl-2-methyl-, hydrochloride (1:1). Grades: ≥95%. CAS No. 63528-29-0. Molecular formula: C6H16ClN. Mole weight: 137.65.
Ethyl 3,5-bis(benzyloxy)benzoate
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Alternative Names: Ethyl 3,5-dibenzyloxybenzoate. CAS No. 50841-46-8. Molecular formula: C23H22O4. Mole weight: 362.425.
Ethyl 3-(acetoxy)crotonate
Ethyl 3-(acetoxy)crotonate is an impurity of Edaravone, which is a medication used to treat stroke and amyotrophic lateral sclerosis (ALS). Alternative Names: 2-Butenoic acid, 3-(acetyloxy)-, ethyl ester; Crotonic acid, 3-hydroxy-, ethyl ester, acetate; Crotonic acid, β-hydroxy-, ethyl ester, acetate; Ethyl 3-(acetyloxy)-2-butenoate; Ethyl 3-acetoxy-2-butenoate; Ethyl 3-acetoxycrotonate; Ethyl acetoacetate enol acetate; Ethyl β-acetoxycrotonate; NSC 167587. Grades: ≥95%. CAS No. 29214-62-8. Molecular formula: C8H12O4. Mole weight: 172.18.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. CAS No. 1039762-39-4. Molecular formula: C46H46N6O3. Mole weight: 730.9.
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Alternative Names: PAPE-ethyl Carbamate; Sorafenib related compound 7. Grades: > 98%. CAS No. 2206827-12-3. Molecular formula: C16H17N3O4. Mole weight: 315.32.
Ethyl 4-amino-2-phenyl-1H-imidazole-5-carboxylate
Ethyl 4-amino-2-phenyl-1H-imidazole-5-carboxylate is a useful research chemical. Alternative Names: Ethyl-5-amino-2-phenylimidazole-4-carboxylate. Grades: 95 %. CAS No. 32704-59-9. Molecular formula: C12H13N3O2. Mole weight: 231.25.
Ethyl 4-bromobenzoate-[d4]
Ethyl 4-bromobenzoate-[d4]. Grades: 95% by HPLC; 98% atom D. CAS No. 787624-25-3. Molecular formula: C9H5D4BrO2. Mole weight: 233.10.
Ethyl 4-hydroxybutanoate, a chemical compound renowned for its widespread usage in pharmaceuticals, fragrances, and food additives, is an intermediate that can be harnessed in the synthesis of numerous drugs, such as anti-inflammatory and anti-cancer agents, making them all the more potent. Moreover, it has demonstrated its sheer versatility as a flavoring agent in the food industry, adding to its already impressive repertoire. Alternative Names: Butanoic acid, 4-hydroxy-, ethyl ester; 4-Hydroxybutanoic acid ethyl ester; Ethyl 4-hydroxybutyrate; 4-Hydroxybutyric acid ethyl ester; NSC617295. Grades: 95%. CAS No. 999-10-0. Molecular formula: C6H12O3. Mole weight: 132.16.
Ethyl 4-(rhamnosyloxy)benzylcarbamate
Ethyl 4-(rhamnosyloxy)benzylcarbamate is a natural compound isolated from the leaves of Moringa oleifera Lam. Alternative Names: Carbamic acid, N-[[4-[(6-deoxy-alpha-L-mannopyranosyl)oxy]phenyl]methyl]-, ethyl ester. Grades: 97.5%. CAS No. 208346-80-9. Molecular formula: C16H23NO7. Mole weight: 341.36.
Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate
Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate, an essential building block for medicinal chemistry, is employed as a key intermediate for synthesizing pharmaceuticals that address a wide spectrum of ailments including cancer, inflammation and bacterial infections. With its intrinsic value in drug discovery, this compound offers an unparalleled opportunity to design novel therapeutic agents with unexplored potential for mitigating a range of medical afflictions. As an indispensable tool in the field of drug development, Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate is instrumental in enabling novel possibilities for treatment. Alternative Names: Ethyl 2-bromothieno[3,2-b]thiophene-3-carboxylate. CAS No. 2055722-78-4. Molecular formula: C9H7BrO2S2. Mole weight: 291.2.
Ethyl cyclopent-1-enecarboxylate
Ethyl cyclopent-1-enecarboxylate (CAS# 10267-94-4 ) is a useful research chemical. Alternative Names: Ethyl 1-cyclopentene-1-carboxylate; ethyl cyclopent-1-ene-1-carboxylate. CAS No. 10267-94-4. Molecular formula: C8H12O2. Mole weight: 140.18.
Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Alternative Names: Diethyl urethane; Diethylcarbamic acid ethyl ester; Carbamic acid, N,N-diethyl-, ethyl ester; NSC 24699; N,N-diethyl O-ethylcarbamate. CAS No. 3553-80-8. Molecular formula: C7H15NO2. Mole weight: 145.20.
Ethylene glycol monobenzoate
Ethylene glycol monobenzoate. CAS No. 94-33-7.
Ethyllucidone
Ethyllucidone can be isolated from the roots of Lindera strychnifolia. Alternative Names: (2Z)-2-[(2E)-1-Ethoxy-3-phenyl-2-propen-1-ylidene]-4-methoxy-4-cyclopentene-1,3-dione; 2-(1-Ethoxy-3-phenylallylidene)-4-Methoxycyclopent-4-ene-1,3-dione. Grades: >98%. CAS No. 1195233-59-0. Molecular formula: C17H16O4. Mole weight: 284.3.
Ethyl N-[[5-methyl-2-(isopropyl)cyclohexyl]carbonyl]glycinate. Alternative Names: N-[[5-Methyl-2-(1-methylethyl)cyclohexyl]carbonyl]glycine ethyl ester; WS 5. Grades: 95%. CAS No. 39668-74-1. Molecular formula: C15H27NO3. Mole weight: 269.38.
Ethyl tetrazole-5-carboxylate
Ethyl Tetrazole-5-carboxylate is a reagent used in the preparation if pyrazole acids which has niacin receptor agonistic activity and is useful for the treatment of dyslipidemia. Alternative Names: Ethyl 1H-tetrazole-5-carboxylate; 1H-Tetrazole-5-carboxylic acid ethyl ester. Grades: 98%. CAS No. 55408-10-1. Molecular formula: C4H6N4O2. Mole weight: 142.12.
Ethynylestradiol Impurity E
An impurity of Estradiol. Estradiol is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Alternative Names: 6-alpha-Hydroxy Ethynylestradiol. Grades: > 95%. CAS No. 27521-34-2. Molecular formula: C20H24O3. Mole weight: 312.41.
Etiracetam
Etiracetam is an acetylcholine agonist used as a nootropic drug of the racetam family. S-enantiomer, Levetiracetam, is more active compared to the opposite R-enantiomer, UCB L-060. Uses: Nootropic drug. Alternative Names: UCB 6474; UCB6474; UCB-6474; 2-(2-oxopyrrolidin-1-yl)butanamide. Grades: 98%. CAS No. 33996-58-6. Molecular formula: C8H14N2O2. Mole weight: 170.21.
Etodolac EP Impurity L
Etodolac EP Impurity L. CAS No. 2789629-50-9.
Etoposide-[13C,d3]
One of the isotope labelled form of Etoposide, which is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class and could be used in form of its salt etoposide phosphate. Alternative Names: (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one-13C-d3. Molecular formula: C28[13C]H29D3O13. Mole weight: 592.58.
Etoricoxib Impurity 7
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Alternative Names: N,N-dimethyl-6-(6-methylpyridin-3-yl)-5-(4-methylsulfonylphenyl)pyridin-3-amine. Grades: > 95%. CAS No. 646459-39-4. Molecular formula: C20H21N3O2S. Mole weight: 367.47.
Etoricoxib N-Oxide
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Alternative Names: 5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide; 2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-, 1-oxide. CAS No. 325855-71-8. Molecular formula: C18H15ClN2O3S. Mole weight: 374.84.
ETP-46321
ETP-46321 is a potent and orally bioavailable PI3K α, δ inhibitor with potent biochemical and cellular activity and good pharmacokinetic properties (PK) after oral dosing. ETP-46321 PK/PD studies showed time dependent downregulation of AKT(Ser473) phosphorylation, which correlates with compound levels in tumor tissue and demonstrating to be efficacious in a GEMM mouse tumor model driven by a K-Ras(G12V) oncogenic mutation. Treatment with ETP-46321 resulted in significant tumor growth inhibition. Alternative Names: ETP46321; ETP-46321; ETP 46321; 5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine. Grades: >98%. CAS No. 1252594-99-2. Molecular formula: C20H27N9O3S. Mole weight: 473.556.
Etravirine
Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine. Uses: Reverse transcriptase inhibitors. Alternative Names: R165335; R-165335; R 165335; TMC 125; TMC-125; TMC125; Etravirine. Intelence. Grades: >98%. CAS No. 269055-15-4. Molecular formula: C20H15BrN6O. Mole weight: 435.28.
Etravirine-[d4]
Etravirine-[d4] is the labelled analogue of Etravirine, which is a drug used for the treatment of HIV and a non-nucleoside reverse transcriptase inhibitor (NNRTI). Uses: The labeled form of etravirine is an inhibitor of hiv reverse transcriptase and could be used in the treatment of hiv infection. Alternative Names: Etravirine D4; 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile-d4; Intelence-d4; R 165335-d4; TMC 125-d4. Grades: 98%. CAS No. 1142095-93-9. Molecular formula: C20H11D4BrN6O. Mole weight: 439.30.
Eucalyptin
Eucalyptin comes from the branch of Eucalyptus globulus. Alternative Names: 5-HYDROXY-7,4'-DIMETHOXY-6,8-DIMETHYLFLAVONE; EUCALYPTIN; 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4-benzopyrone; 5-Hydroxy-2-(4-methoxyphenyl)-6,8-dimethyl-7-methoxy-4H-1-benzopyran-4-one; 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one; 5-Hydroxy-7-Methoxy-2-(4-Methoxyphenyl)-6,8-diMethyl-4H-chroMen-4-one. Grades: >98%. CAS No. 3122-88-1. Molecular formula: C19H18O5. Mole weight: 326.4.
Eucomol
Eucomol is an antibacterial flavonoid isolated from Eucomis vandermerwei. Alternative Names: Eucomol; 17934-12-2; (3S)-3,5,7-trihydroxy-3-[(4-methoxyphenyl)methyl]-2H-chromen-4-one; CHEMBL4557071; HY-N7321; AKOS040761714; XE161750; CS-0113294. Grades: 98.0%. CAS No. 17934-12-2. Molecular formula: C17H16O6. Mole weight: 316.31.
Eudesmin
Eudesmin is purified from the dry leaves of Haplophyllum perforatum Kar.et Kir. Eudesmin can induce vascular relaxation in rat aorta, which is mediated by release of nitric oxide and prostanoid through the involvement of histamine receptor present in the endothelial cells. (+)-Eudesmin has neuritogenic activity. It can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways. Eudesmin shows anti-inflammatory effects, significantly inhibits TNF-alpha production by lipopolysaccharide (LPS)-stimulated murine macrophage RAW264.7 without displaying cytotoxicity, and can significantly attenuate T cell proliferation stimulated by concanavalin A (Con A) in a dose-dependent manner. Alternative Names: (+)-Eudesmin; 3,6-bis(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan. Grades: 98.0%. CAS No. 29106-36-3. Molecular formula: C22H26O6. Mole weight: 386.44.
Euglobal Ia2
Euglobal Ia2, an innovative small-molecule agent, exhibits substantial capacity as an antitumor modulator. Conspicuously, the compound illustrates efficacy in curbing the growth of human cancer cells, with a heightened emphasis on those originating from the thoracic and mammary apparatuses. Accomplishing this feat, Euglobal Ia2 modulates the Akt pathway intricately involved in carcinogenesis. Being multifunctional, Euglobal Ia2 offers a myriad of avenues for therapeutic intervention for various oncological cases. Alternative Names: Euglobal Ia1; Euglobal-Ia1; EuglobalIa1. Grades: 96.0%. CAS No. 77794-63-9. Molecular formula: C23H30O5. Mole weight: 386.488.
EUK 134
EUK-134 is a unique small molecule antioxidant and anti-aging active substance with excellent antioxidant properties. It possesses the dual effects of superoxide dismutase SOD and catalase CAT, effectively improving cell damage caused by oxidative stress, and inhibiting the formation of β-amyloid protein and related amyloid protein fibers. The EUK-134 facilitates the penetration and absorption of the skin surface, enabling direct entry into the skin to exert its effects and optimize its potent efficacy. Essentially functioning as a catalyst, it remains unaffected by the number of reactions, allowing for reusability with minimal quantity while maintaining stability in nature. It can be used in anti-aging products, sunscreen products, whitening products and skin repair products. Alternative Names: Manganese, chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]-, (SP-5-13)-; (SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]manganese; Manganese, chloro[[2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxyphenolato]](2-)-N2,N2',O1,O1']-; Phenol, 2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxy-, manganese complex; Chloro[bis(3,3'-di-methoxysalicylic)ethylenediamine] manganese; EUK134; EUK-134; Ethylbisiminomethylguaiacol manganese chloride. Grades: >98%. CAS No. 81065-76-1. Molecular formula: C18H18ClMnN2O4
Eupatilin
Eupatilin isolated from the leaves of Artemisia argyi Levl.et Vant. It shows inhibitory effects on the human ileum and colon. Uses: Anti-tumor; anti-inflammatory. Alternative Names: 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one;5,7-Dihydroxy-3',4',6-trimethoxyflavone. Grades: 0.98. CAS No. 22368-21-4. Molecular formula: C18H16O7. Mole weight: 344.31.
Eupatolide
Eupatolide is a natural compound extracted from Inula britannica, which is used in Eastern Asia to treat bronchitis, disorders of the digestive system and inflammation. Eupatolide exhibits inhibitory effects on the migration and invasion of breast cancer cells. Alternative Names: Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-4-hydroxy-6,10-dimethyl-3-methylene-, (3aR,4R,6E,10E,11aR)-; (3aR,4R,6E,10E,11aR)-4-Hydroxy-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one. Grades: ≥95%. CAS No. 6750-25-0. Molecular formula: C15H20O3. Mole weight: 248.32.
Euphorbia factor L1
Euphorbia factor L1 is isolated from the herbs of Euphorbia pekinensis Rupr. Alternative Names: (1aR,4aR,6S,7S,7aR,8S,9R,11aS)-4a,8-Diacetoxy-1,1,3,6-tetramethyl-4-oxo-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-7-yl phenylacetate; 10-epi-Eupatoroxin. Grades: >=98%. CAS No. 76376-43-7. Molecular formula: C32H40O8. Mole weight: 552.7.
Euphorbia factor L3
Euphorbia factor L3 is isolated from the seeds of Euphorbia lathyris L. It is a melanine production inhibitor. Uses: Antitumor. Alternative Names: 5,15-Diacetyl-3-benzoyllathyrol; Diacetyl benzoyl lathyrol. Grades: >=98%. CAS No. 218916-52-0. Molecular formula: C31H38O7. Mole weight: 522.63.
Eurycomanone
Eurycomanone is a diterpenoid showing anti-cancer activity. Alternative Names: Pasakbumin-A. Grades: 98%. CAS No. 84633-29-4. Molecular formula: C20H24O9. Mole weight: 408.4.
Euscaphic acid
Euscaphic acid is isolated from the dried fruit of Ziziphus jujuba. It inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations. Uses: Antifungal; anti-diabetic activity; anti-inflammatory. Alternative Names: Acuminatic acid. Grades: 98%. CAS No. 53155-25-2. Molecular formula: C30H48O5. Mole weight: 488.7.
Evacetrapib
Evacetrapib (LY2484595) is a drug that inhibits cholesterylester transfer protein, which transfers and thereby increases high-density lipoprotein and lowers low-density lipoprotein. Alternative Names: LY2484595; LY 2484595; LY-2484595. Grades: 0.98. CAS No. 1186486-62-3. Molecular formula: C31H36F6N6O2. Mole weight: 638.659.
Evolitrine
Evolitrine is an alkaloid isolated from Fructus Evodiae. Alternative Names: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. Grades: 98%. CAS No. 523-66-0. Molecular formula: C13H11NO3. Mole weight: 229.23.
EW-7197
EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β / Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Alternative Names: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grades: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433.
Excisanin A
Excisanin A is a natural diterpenoid compound found in several plants. Alternative Names: 1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one. Grades: >95%. CAS No. 78536-37-5. Molecular formula: C20H30O5. Mole weight: 350.45.
Excisanin B
Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Alternative Names: 1alpha,7alpha,14beta-Trihydroxy-12alpha-acetoxykaura-16-ene-15-one. Grades: 98.0%. CAS No. 78536-36-4. Molecular formula: C22H32O6. Mole weight: 392.49.
Exoticin
Exoticin isolated from the herbs of Murraya exotica. Alternative Names: 3,3',4',5,5',6,7,8-octamethoxyflavone; 3,5,6,7,8-Pentamethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-on e. Grades: 0.97. CAS No. 13364-94-8. Molecular formula: C23H26O10. Mole weight: 462.5.
(E/Z)-Endoxifen
One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Alternative Names: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: > 95%. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.50.
Ezetimibe
Ezetimibe produces a significant reduction in total cholesterol, LDL cholesterol, and triglycerides as well as a small but significant increase in HDL cholesterol. Alternative Names: SCH 58235; SCH-58235; SCH58235; Ezetimibe, Zetia, Ezetrol. Grades: >98%. CAS No. 163222-33-1. Molecular formula: C24H21F2NO3. Mole weight: 409.4.
Ezetimibe-[d4]
Ezetimibe-[d4] is the labelled analogue of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor. Alternative Names: Ezetimibe D4; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl-d4)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Sch-58235-d4. Grades: >98% by HPLC; >98% atom D. CAS No. 1093659-89-2. Molecular formula: C24H17D4F2NO3. Mole weight: 413.45.
Ezetimibe Dehydoxy Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Alternative Names: 3-Dehydroxy Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 204589-58-2. Molecular formula: C24H21F2NO2. Mole weight: 393.44.
Ezetimibe Desfluoro Methyl Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Alternative Names: 4"DeFluoro-4"methyl-ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.47.
Ezetimibe Phenoxy Glucuronide-[d4]
Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Alternative Names: Ezetimibe D4 Phenoxy Glucuronide. Grades: 95% by HPLC; 98% atom D. CAS No. 1426174-41-5. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57.
Fabomotizole
Fabomotizole. CAS No. 173352-21-1.
Fabomotizole hydrochloride
Fabomotizole hydrochloride. CAS No. 173352-39-1.
Famciclovir Impurity 8
An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Alternative Names: 9-(4-Acetoxy-2-acetoxymethyl-but-1-yl)-2-aminopurine. Grades: > 95%. CAS No. 126589-69-3. Molecular formula: C14H19N5O4. Mole weight: 321.34.
Famciclovir N7-Isomer
An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Alternative Names: 2-[2-(2-Amino-7H-purin-7-yl)ethyl]-1,3-propanediol 1,3-Diacetate. Grades: > 95%. CAS No. 131266-15-4. Molecular formula: C14H19N5O4. Mole weight: 321.34.
Famotidine
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. Unlike cimetidine, the first H2 antagonist, famotidine has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs. Alternative Names: Famotidine, Famotidine Hydrochloride, MK-208, Pepcid, YM-11170, YM11170, YM 11170, MK 208, MK208. Grades: >98%. CAS No. 76824-35-6. Molecular formula: C8H15N7O2S3. Mole weight: 337.45.
Famotidine Impurity E
An impurity of Famotidine. Famotidine is a histamine H8 receptor antagonist that inhibits stomach acid production. Alternative Names: Famotidine disulfide; Famotidine related compound E; Bis[(2-guanidino-4-thiazolyl)methyl]disulfide. Grades: > 95%. CAS No. 129083-44-9. Molecular formula: C10H14N8S4. Mole weight: 374.53.
Famotidine Related Compound B Dimaleate
An impurity of Famotidine. Famotidine is a histamine H5 receptor antagonist that inhibits stomach acid production. Alternative Names: Famotidine EP Impurity B (Dimaleate salt); 2,2'-(((((1,1-dioxido-4H-1,2,4,6-thiatriazine-3,5-diyl)bis(ethane-2,1-diyl))bis(sulfanediyl))bis(methylene))bis(thiazole-4,2-diyl))diguanidine dimaleate; N,N'''-[2H-1,2,4,6-Thiatriazine-3,5-diylbis(2,1-ethanediylthiomethylene-4,2-thiazolediyl)]bisguanidine S,S-dioxide (Z)-2-butenedioate (1:2). Grades: 95%. CAS No. 109467-08-5. Molecular formula: C24H31N11O10S5. Mole weight: 793.90.
Fampridine Impurity 3
A derivative of Fampridine. Fampridine is a potent convulsant. Alternative Names: N-(4-Pyridyl)-2-Hydroxybutyramide; Butanamide, 2-hydroxy-N-4-pyridinyl-. Grades: > 95%. CAS No. 1864897-67-5. Molecular formula: C9H12N2O2. Mole weight: 180.21.
Farrerol
Farrerol is isolated from the leaves of Rhododendron dauricum L. Uses: Antioxidative activity. Alternative Names: 6,8-Dimethyl-4',5,7-trihydroxyflavanone; (S)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone; 5,7,4'-Trihydroxy-6,8-Dimethoxyflavanone. Grades: 98%. CAS No. 24211-30-1. Molecular formula: C17H16O5. Mole weight: 300.3.
Fasoracetam
Fasoracetam is a GABA receptor modulator potentially for the treatment of attention deficit hyperactivity disorder. Alternative Names: (5R)-5-(piperidine-1-carbonyl)-2-pyrrolidone; (5R)-5-piperidin-1-ylcarbonylpyrrolidin-2-one. CAS No. 110958-19-5. Molecular formula: C10H16N2O2. Mole weight: 196.248.
FDI 6
FDI 6 is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) (IC50 value 22.5 μM) that suppresses FOXM1 binding to DNA. FDI6 displaces FOXM1 from genomic targets in MCF-7 breast cancer cells, and downregulates concomitant transcription. Alternative Names: FDI-6; FDI 6; FDI6; NCGC00099374; NCGC-00099374; NCGC 00099374; 3-amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide; 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; AC1NPA9B. Grades: 99%. CAS No. 313380-27-7. Molecular formula: C19H11F4N3OS2. Mole weight: 437.43.
Febrifugine dihydrochloride
Febrifugine is a quinazolinone alkaloid isolated from the Chinese herb Dichroa febrifuga. Alternative Names: (+)-Febrifugine dihydrochloride. Grades: > 95%. CAS No. 32434-42-7. Molecular formula: C16H21Cl2N3O3. Mole weight: 374.26.
Febuxostat-[d7]
Febuxostat-[d7] is the labelled analogue of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Alternative Names: Febuxostat D7; 2-[3-Cyano-4-(2-methylpropoxyphenyl]-4-methyl-5-thiazolecarboxylic Acid-d7; 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid-d7; TEI 6720-d7; TMX 67-d7; 2-(3-Cyano-4-{[2-(2H3)methyl(2,3,3,3-2H4)propyl]oxy}phenyl)-4-methyl-1,3-thiazole-5-carboxylic acid. Grades: > 95%. CAS No. 1285539-74-3. Molecular formula: C16H9D7N2O3S. Mole weight: 323.42.
Febuxostat Impurity 23
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Grades: 95%. CAS No. 2073891-59-3. Molecular formula: C15H13NO5S. Mole weight: 319.33.
Felodipine
Felodipine is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM. It can lower blood pressure by reducing peripheral vascular resistance via a highly selective effect on smooth muscle in arteriolar resistance vessels. Alternative Names: Plendil; Flodil; Munobal; Renedil. Grades: >98%. CAS No. 72509-76-3. Molecular formula: C18H19Cl2NO4. Mole weight: 384.25.
(±)-Felodipine-[d3] (2,3-dichlorophenyl-[d3])
One of the labelled form of (±)-Felodipine, which could be used as a dihydropyridine calcium channel blocker. Alternative Names: 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2-methyl-6-(methyl-d3)-1,4-dihydropyridine-3,5-dicarboxylate. Grades: 95% by HPLC; 98% atom D. CAS No. 1219795-30-8. Molecular formula: C18H16D3Cl2NO4. Mole weight: 387.28.
(±)-Felodipine-[d5]
(±)-Felodipine-[d5] is the labelled analogue of (±)-Felodipine, which is a dihydropyridine calcium channel blocker used to treat high blood pressure. Alternative Names: Felodipine D5; rac Felodipine (Ethoxy-d5); (±)-Felodipine-d5; 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl-d5 methyl ester; Plendil-d5; Flodil-d5; Renedil-d5; Feloday-d5; Munobal-d5; Splendil-d5. Grades: >95%. CAS No. 1242281-38-4. Molecular formula: C18H14D5Cl2NO4. Mole weight: 389.29.
Fenazox
Amfenac is a COX inhibitor with IC50 of 0.25 and 0.15 μM for COX-1 and COX-2, respectively. Alternative Names: Amfenac sodium hydrate; Sodium 2-(2-amino-3-benzoylphenyl)acetate hydrate. Grades: 98.0%. CAS No. 61618-27-7. Molecular formula: C15H12NO3·H2O·Na. Mole weight: 295.26.