BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Diphyllin | Diphyllin is a lignan with anti-inflammatory activities. Alternative Names: Diphyllin|22055-22-7|9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-3H-benzo[f][2]benzofuran-1-one|UNII-W4PN5LDP26|W4PN5LDP26|MLS000106853|CHEBI:4645|SMR000111229|9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-3H-benzo[f]isobenzofuran-1-one|9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one; NSC 309691|Naphtho(2,3-c)furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4-hydroxy. Grades: 98%. CAS No. 22055-22-7. Molecular formula: C21H16O7. Mole weight: 380.35. |  |
| Diprotin A TFA | Diprotin A TFA is a dipeptidyl peptidase IV (DPP-IV) inhibitor. Alternative Names: L-isoleucyl-L-prolyl-L-isoleucine trifluoroacetic acid. Grades: 98%. CAS No. 209248-71-5. Molecular formula: C19H32F3N3O6. Mole weight: 455.47. | |
| Dipterocarpol | Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng which is from the herbs of Aglaia odorata. Alternative Names: 20-Hydroxy-5α-dammar-24-en-3-one;20-Hydroxydammara-24-ene-3-one;(5R,8R,9R,10R,14R)-17-((S)-1-Hydroxy-1,5-dimethyl-hex-4-enyl)-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[A]phenanthren-3-one. Grades: >98%. CAS No. 471-69-2. Molecular formula: C30H50O2. Mole weight: 442.7. | |
| Dipyrazino[2,3-f:2,3-h]quinoxaline-2,3,6,7,10,11-hexacarbonitrile | Dipyrazino[2,3-f:2,3-h]quinoxaline-2,3,6,7,10,11-hexacarbonitrile (CAS# 105598-27-4 ) is a useful research chemical. Alternative Names: Hexaazatriphenylenehexacabonitrile; HAT-CN; Dipyrazino[2,3-f:2',3'-h]quinoxalinehexacarbonitrile. Grades: 95 %. CAS No. 105598-27-4. Molecular formula: C18N12. Mole weight: 384.27. | |
| Diroximel Fumarate | Diroximel Fumarate is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. It reduces the progressive damage to nerve cells via activating the Nrf2 pathway. It also acts as a NF-kappa B inhibitor. Alternative Names: ALKS8700; ALKS 8700; ALKS-8700; 2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate; 1-[2-(2,5-Dioxo-1-pyrrolidinyl)ethyl] 4-methyl (2E)-2-butenedioate; 2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester. Grades: 98%. CAS No. 1577222-14-0. Molecular formula: C11H13NO6. Mole weight: 255.22. | |
| Disodium Cocoyl Glutamate | Disodium Cocoyl Glutamate. CAS No. 68187-30-4. | |
| DiZPK | DiZPK, a photocrosslinking amino acid, could be significant in revealling the physiological and functions of some proteins acting as a genetically encoded. Uses: Dizpk could be significant in revealling the physiological and functions of some proteins acting as a genetically encoded. Alternative Names: DiZPK; CS-4117; 3-(3-Methyl-3H-diazirin-3-yl)-propamino-carbonyl-Ne-L-lysine. Grades: 98%. CAS No. 1337883-32-5. Molecular formula: C12H23N5O3. Mole weight: 285.34. | |
| DL-α-Hydroxystearic acid | 2-Hydroxyoctadecanoic acid is a natural product found in Allamanda cathartica, Brassica napus, and other organisms. It plays a crucial role as an intermediate in the production of several other fatty acids, such as linoleic acid, oleic acid, and arachidonic acid. Alternative Names: 2-Hydroxystearic acid; alpha-Hydroxystearic acid; DL-alpha-Hydroxystearic acid. Grades: 98%. CAS No. 629-22-1. Molecular formula: C18H36O3. Mole weight: 300.48. | |
| DLin-MC4-DMA | DLin-MC4-DMA is a cationic lipid which can be used for delivery of nucleic acids. Alternative Names: DLin-M-C4-DMA; (10Z,13Z)-1-(9Z,12Z)-9,12-Octadecadien-1-yl-10,13-nonadecadien-1-yl 5-(dimethylamino)pentanoate. Grades: 98%. CAS No. 1226909-66-5. Molecular formula: C44H81NO2. Mole weight: 656.12. | |
| DL-Tetrahydroberberine | Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. Alternative Names: 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-; 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Berberine, 9-deoxy-16,17-dihydro-; Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-; (±)-Canadine; (±)-Tetrahydroberberine; Berberine, tetrahydro-; Canadine; dl-Canadine; NSC 36351; NSC 94918; Tetrahydroberberine; Tetrahydroberineper; Tetrahydroumbellatine; Xanthopuccine. Grades: ≥95%. CAS No. 522-97-4. Molecular formula: C20H21NO4. Mole weight: 339.38. | |
| D-Lys(20)-Semaglutide | D-Lys(20)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-[Lys]-20-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| DM1-SPP | DM1 with a reactive linker SPP, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. Alternative Names: N2'-deacetyl-N2'-[3-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-methyl-4-oxobutyl]dithio]-1-oxopropyl]-Maytansine; DM1 SPP. Grades: ≥98%. CAS No. 452072-20-7. Molecular formula: C44H59ClN4O14S2. Mole weight: 967.54. | |
| DM3 | DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Alternative Names: N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)- maytansine. Grades: ≥95%. CAS No. 796073-54-6. Molecular formula: C37H52ClN3O10S. Mole weight: 766.34. | |
| DM3-SMe | DM3-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Alternative Names: N2'-deacetyl-N2'-[4-(R,S)-(methyldithio)-1-oxopentyl]maytansine. Grades: ≥98%. CAS No. 796073-70-6. Molecular formula: C38H54ClN3O10S2. Mole weight: 812.43. | |
| DM4-SMe | DM4-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Alternative Names: N2'-deacetyl-N2'-[4-methyl-4-(methyldithio)-1-oxopentyl]maytansine. Grades: ≥98%. CAS No. 796073-68-2. Molecular formula: C39H56ClN3O10S2. Mole weight: 826.46. | |
| DM4-SPDB | DM4 with a reactive linker SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Alternative Names: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2 S)-2-{[4-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}disulfanyl)-4-methylpentanoyl](methyl)amino}propanoate (non-preferred name); DM4 SPDB. Grades: ≥98%. CAS No. 1626359-62-3. Molecular formula: C46H63ClN4O14S2. Mole weight: 995.59. | |
| DM4-SPDP | DM4 with a reactive linker SPDP, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Alternative Names: Maytansinoid DM4- succinimidyl 3-(2-pyridyldithio)propionate; DM4 SPDP. Grades: ≥98%. CAS No. 2245698-48-8. Molecular formula: C45H61ClN4O14S2. Mole weight: 981.57. | |
| DMPE-PEG | DMPE-PEG, a polyethylene glycol derivative, is a vital component in the development of advanced drug delivery platforms focused on combatting cancer and infectious diseases. Through its unique properties, it plays a crucial role in improving the solubility and stability of pharmaceutical agents, thereby heightening their therapeutic potential. Alternative Names: 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-n-PEG; 14:0 PEG2000 PE; DMPE-PEG2000; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium; Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxotetradecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphapentacos-1-yl]-ω-methoxy-, ammonium salt (1:1); 14:0 PEG 2000 PE; PEG DMG 2000. Grades: >95%. CAS No. 474922-82-2. Molecular formula: (C2H4O)nC35H68NO10P.H3N. | |
| DMRIE | DMRIE is a quaternary ammonium compound with surfactant properties. It features a hydrophilic head with dimethyl and hydroxyethyl groups, and two hydrophobic tetradecyl (C14) alkyl chains, making it effective in forming micelles and emulsifying agents. The bromide counterion balances the charge of the ammonium group. This compound is commonly used in formulations requiring surfactants, such as in detergents, personal care products, and possibly in drug delivery systems due to its amphiphilic nature. Alternative Names: N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-1-propaniminium Bromide; 1-Propanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-, bromide (1:1); Dimethyl-2-hydroxyethyl-2,3-ditetradecyloxypropylammonium bromide; Dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium; N-[1-(2,3-Ditetradecyloxy)propyl]-N,N-dimethyl-N-hydroxyethylammonium bromide; N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)propan-1-aminium bromide. Grades: ≥95%. CAS No. 153312-64-2. Molecular formula: C35H74BrNO3. Mole weight: 636.87. | |
| DMU-212 | DMU-212, an orally active methylated derivative of Resveratrol, has antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. It induces mitotic arrest by inducing apoptosis and activating ERK1/2 protein. Alternative Names: 3,4,5,4'-Tetramethoxystilbene; (E)-3,4,5,4'-Tetramethoxystilbene; 1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; trans-3,4,5,4'-tetramethoxystilbene; NSC631365; 3,4,4',5-Tetramethoxy-trans-stilbene; 1,2,3-Trimethoxy-5-[(E)-2-(4-methoxyphenyl)vinyl]benzene; (E)-1,2,3-trimethoxy-5-(4-methoxystyryl)benzene. Grades: 95%. CAS No. 134029-62-2. Molecular formula: C18H20O4. Mole weight: 300.35. | |
| DMXAA | DMXAA is a STING agonist that induces antitumor immunological responses. Uses: Antineoplastic agents. Alternative Names: 9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo-; 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid; 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid; 5,6-Dimethyl-9-oxo-9H-xanthen-4-ylacetic acid; 5,6-Dimethylxanthenone-4-acetic acid; ASA404; ASA 404; ASA404; AS1404; AS 1404; AS1404; D5817; NSC 640488; Vadimezan. Grades: ≥95%. CAS No. 117570-53-3. Molecular formula: C17H14O4. Mole weight: 282.29. | |
| DNA2 Inhibitor C5 | DNA2 Inhibitor C5. CAS No. 35973-25-2. | |
| (D)-(+)-Neopterin | Neopterin, a pyrazino-pyrimidine compound derived from GTP, n is a precursor of tetrahydrobiopterin and can be used as a biochemical marker indicative of cell proliferation. Neopterin is synthesized in response to interferon-γ stimulation, and used as a marker of T helper cell-induced immune activation. Neopterin is also an indicator of oxidative stress, and modulates the effects of reactive oxygen species (ROS). Alternative Names: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; Neopterin; 2-Amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)pteridine; 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone; 6-D-erythro-Neopterin; D-(+)-Neopterin; D-erythro-Neopterin. Grades: ≥98% by HPLC. CAS No. 2009-64-5. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
| Dobutamine hydrochloride | Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock. Its primary mechanism is direct stimulation of β1 receptors of the sympathetic nervous system. Alternative Names: 4-(2-((4-(4-hydroxyphenyl)butan-2-yl)amino)ethyl)benzene-1,2-diol hydrochloride; LY 81929; LY-81929; LY81929; Dobutamine; Dobutamina. Grades: >98%. CAS No. 49745-95-1. Molecular formula: C18H24ClNO3. Mole weight: 337.84. | |
| Docarpamine | Docarpamine is a prodrug of dopamine. Alternative Names: docarpamine; 74639-40-0; Tanadopa; TA-870; UNII-RPQ57D8S72. Grades: 95%. CAS No. 74639-40-0. Molecular formula: C21H30N2O8S. Mole weight: 470.54. | |
| Docosaenoyl ethanolamide | Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines. Alternative Names: Erucicoyl-EA; Erucicoyl-ethanolamine; N-(13Z-docosanoyl)-ethanolamine; 13-Docosenamide, N-(2-hydroxyethyl)-, (13Z)-; 13(Z)-docosenoyl ethanolamide. Grades: 95%. CAS No. 18190-74-4. Molecular formula: C24H47NO2. Mole weight: 381.64. | |
| Docosanedioic acid | Behenic acid, or docosanedioic acid, a saturated fatty acid, is an effective emollient in the cosmetics industry due to its remarkable moisturizing properties. Behenic acid's therapeutic potential is another aspect of interest, as it has been researched for the treatment of various maladies, including multiple sclerosis and Parkinson's disease. Moreover, it is demonstrated to have a positive impact on chondrogenesis, which is vital for the formation of cartilage tissue due to its exceptional proliferative force. It is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Alternative Names: Felogenic acid; Phellogenic acid; 1,22-Docosanedioic acid; 1,20-Eicosanedicarboxylic acid; Docosan-1,22-dioic acid. Grades: 95%. CAS No. 505-56-6. Molecular formula: C22H42O4. Mole weight: 370.57. | |
| Dodovislactone B | Dodovislactone B is extracted from the aerial parts of Dodonaea viscosa. Alternative Names: Dodovislactone B; 1616683-55-6; (4Ar,5S,6R,8aR)-5-[2-(2-methoxy-5-oxo-2H-furan-3-yl)ethyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid. CAS No. 1616683-55-6. Molecular formula: C21H30O5. Mole weight: 362.46. | |
| Dodovisone B | Dodovisone B is extracted from the aerial parts of Dodonaea viscosa. Alternative Names: Dodovisone B; 1616683-51-2; 5,7-dihydroxy-2-[3-hydroxy-8-(4-hydroxy-3-methylbutyl)-2,2-dimethyl-3,4-dihydrochromen-6-yl]-3,6-dimethoxychromen-4-oneB0005-2677042-[3,4-dihydro-3-hydroxy-8-(4-hydroxy-3-methylbutyl)-2,2-dimethyl-2h-1-benzopyran-6-yl]-5,7-dihydroxy-3,6-dimethoxy-4h-1-benzopyran-4-one. Grades: 90%. CAS No. 1616683-51-2. Molecular formula: C27H32O9. Mole weight: 500.54. | |
| Domperidone Impurity F | An impurity of the gastrokinetic and antinauseant drug Domperidone. Alternative Names: 3'-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine. Grades: > 95%. CAS No. 1391053-55-6. Molecular formula: C37H42Cl2N8O3. Mole weight: 717.69. | |
| Donepezil Alkene Pyridine N-Oxide | Donepezil Alkene Pyridine N-Oxide is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Alternative Names: 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-; 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one; 4-[(5,6-dimethoxy-1-indanon-2-ylidene)methyl]pyridine N-oxide; 4-((5,6-Dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridine 1-oxide. Grades: ≥95%. CAS No. 896134-06-8. Molecular formula: C17H15NO4. Mole weight: 297.31. | |
| Donepezil Impurity 3 | Donepezil impurity. Alternative Names: 3-Keto Donepezil; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-1H-indene-1,3(2H)-dione; 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-indene-1,3(2H)-dione. Grades: > 95%. CAS No. 1023500-88-0. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
| Donepezil N-Oxide | A metabolite of Donepezil, which is a medication for the treatment of Alzheimer's disease. Alternative Names: rac (cis / trans) Donepezil N-Oxide; 2,3-Dihydro-5,6-dimethoxy-2-[[1-oxido-1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one. Grades: 95%. CAS No. 120013-84-5. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| Donepezil Open-Ring Keto Acid | Donepezil Open-Ring Keto Acid is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Alternative Names: 2-[3-(1-Benzylpiperidin-4-yl)-2-oxopropyl]-4,5-dimethoxybenzoic acid. CAS No. 197010-25-6. Molecular formula: C24H29NO5. Mole weight: 411.498. | |
| DOPE-PEG-FA ammonium salt | DOPE-PEG-FA is a heterobifunctional PEGylation reagent with an unsaturated DOPE phospholipid and a folic acid. It can be used in targeted drug delivery with the lipid bilayer. Alternative Names: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Folic acid ammonium salt. Grades: 90%. | |
| Doripenem hydrate | Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections. Alternative Names: S-4661; S 4661; S4661. Grades: >98%. CAS No. 364622-82-2. Molecular formula: C15H24N4O6S2.H2O. Mole weight: 438.52. | |
| Dorsomorphin 2HCl | Dorsomorphin (hydrochloride) is a potent, reversible inhibitor of AMP kinase (AMPK; Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. CAS No. 1219168-18-9. Molecular formula: C24H25N5O.2HCl. Mole weight: 472.414. | |
| Dorzolamide-[d5] | Dorzolamide-[d5] is the labelled analogue of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor used to lower the pressure of eyes with glaucoma. Alternative Names: Dorzolamide D5; (4S,6S)-4-[(2H5)Ethylamino]-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide. Grades: 95% by HPLC; 95% atom D. CAS No. 1227097-70-2. Molecular formula: C10H11D5N2O4S3. Mole weight: 329.47. | |
| Dorzolamide Hydrochloride | Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Alternative Names: Dorzolamide HCl; TRUSOPT; (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride; (4S-trans)-4-(ethylamino)-5,6-dihydro-6-methyl4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride. Grades: >98%. CAS No. 130693-82-2. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.886. | |
| DOTA-GA(tBu)4 | DOTA-GA(tBu)4. Alternative Names: 5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid. CAS No. 306776-79-4. Molecular formula: C35H64N4O10. Mole weight: 700.9. | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Alternative Names: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grades: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. DOTA-PEG5-azide can be used in the synthesis of a series of PROTACs. Alternative Names: DOTA-PEG5-C2-azide. Grades: 95%. Molecular formula: C28H52N8O12. Mole weight: 692.76. | |
| Dovitinib | Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Alternative Names: Dovitinib, TKI258; TKI 258;TKI-258; CHIR 265; CHIR265; CHIR-265; RAF-265; RAF 265; RAF265. Grades: > 95%. CAS No. 405169-16-6. Molecular formula: C21H21FN6O. Mole weight: 392.429. | |
| Doxercalciferol | Doxercalciferol is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). Alternative Names: Hectorol; 1-Hydroxyergocalciferol; 1alpha-Hydroxyergocalciferol; 1-alpha-Hydroxyvitamin D2. Grades: 98%. CAS No. 54573-75-0. Molecular formula: C28H44O2. Mole weight: 412.65. | |
| Doxofylline Impurity 1 | Doxofylline Impurity 1 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Alternative Names: 1-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide. Grades: > 95%. CAS No. 1429636-74-7. Molecular formula: C10H16N4O3. Mole weight: 240.26. | |
| Doxofylline Impurity 2 | Doxofylline Impurity 2 (Theophylline Impurity 2) is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Alternative Names: Theophylline Impurity 1; 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-acetaldehyde; 7-(Formylmethyl)theophylline; 7-Theophyllineacetaldehyde. Grades: > 95%. CAS No. 5614-53-9. Molecular formula: C9H10N4O3. Mole weight: 222.20. | |
| D-Phe(22)-Semaglutide | D-Phe(22)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-[Phe]-22-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Dracorhodin perchlorate | Dracorhodin perchlorate can inhibit high glucose-induced serum and glucocorticoid induced protein kinase 1 (SGK1) and fibronectin (FN) expression in human mesangial cells, and this may be a part of the mechanism of preventing and treating renal fibrosis of DN. Alternative Names: Dracorhodin perochlorate; Dracohodin perochlorate. Grades: >98%. CAS No. 125536-25-6. Molecular formula: C17H15ClO7. Mole weight: 366.75. | |
| Dregeoside Da1 | Dregeoside Da1 is a natural steroid found in the herbs of Dregea volubilis. Alternative Names: [4-(Methylsulfonyl)phenyl]methanaminium chloride. Grades: >95%. CAS No. 98665-65-7. Molecular formula: C42H70O15. Mole weight: 815.0. | |
| Dregeoside Ga1 | Dregeoside Ga1 is a natural steroid found in the herbs of Dregea volubilis. Alternative Names: Dregeoside G, 7-Chloro-4-iodoquinoline. Grades: >93%. CAS No. 98665-66-8. Molecular formula: C49H80O17. Mole weight: 941.17. | |
| D-Ribose-[1,2-13C2] | Labelled D-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. Alternative Names: Ribose-1,2-13C2; D-(-)-Ribose-1,2-13C2. Grades: ≥99% by HPLC; 99% atom 13C. CAS No. 209909-88-6. Molecular formula: C3[13C]2H10O5. Mole weight: 152.12. | |
| Dronedarone | Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties. Uses: Antiarrhythmic. Alternative Names: Multaq; SR-33589; SR33589; SR 33589; SR-33589B. Grades: >98%. CAS No. 141626-36-0. Molecular formula: C31H44N2O5S. Mole weight: 556.76. | |
| Dronedarone-[d6] Hydrochloride | Dronedarone-[d6] HCl is a labelled analogue of Dronedarone. Dronedarone is a medication used to treat atrial fibrillation and atrial flutter. Alternative Names: N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide-d6 Hydrochloride; SR33589-d6 Hydrochloride; Multaq-d6 Hydrochloride. Grades: >95%. CAS No. 1329809-23-5. Molecular formula: C31H39D6ClN2O5S. Mole weight: 599.26. | |
| Droxidopa | Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Alternative Names: (βR)-β,3-Dihydroxy-L-tyrosine; threo-β,3-Dihydroxy-L-tyrosine; L-threo-3-(3,4-Dihydroxyphenyl)serine; (-)-threo-3,4-Dihydroxyphenylserine; (2S,3R)-3-(3,4-Dihydroxyphenyl)-2-amino-3-hydroxypropanoic Acid; DOPS; L-DOPS; L-Threodops; L-threo-3,4-Dihydroxyphenylserine; L-threo-DOPS; L-threo-β-(3,4-Dihydroxyphenyl)serine; SM 5688; threo-Dopaserine. Grades: >98%. CAS No. 23651-95-8. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| D-Ser(12)-Semaglutide | D-Ser(12)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-Ser-12-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30R,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamo. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| DSG-PEG-NH2, MW2K | DSG-PEG-NH2, MW2K. | |
| DSP-6952 hydrobromide | DSP-6952 is a novel 5-HT4 receptor partial agonist that inhibits visceral hypersensitivity and ameliorates gastrointestinal dysfunction in experimental animals. CAS No. 1184661-33-3. Molecular formula: C21H32BrClN4O5. Mole weight: 535.86. | |
| DSPE-PEG 2000 Maleimide | DMG-PEG-MAL, a multifunctional reactive polymer, plays a critical role in drug delivery and bioconjugation within the realm of biomedicine. Its utility extends to precise targeting of particular cells or tissues in the context of treating diverse ailments, including but not limited to cancer and inflammatory disorders. Alternative Names: DSPE-PEG (2000) Maleimide; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)]. Grades: ≥95%. | |
| DSPE-PEG-maleimide ammonium salt | DSPE-PEG-maleimide ammonium salt. CAS No. 474922-22-0. | |
| DSPE-PEG-Maleimide (MW 2000) sodium | DMG-PEG-MAL, a multifunctional reactive polymer, plays a critical role in drug delivery and bioconjugation within the realm of biomedicine. Its utility extends to precise targeting of particular cells or tissues in the context of treating diverse ailments, including but not limited to cancer and inflammatory disorders. Alternative Names: DSPE-PEG 2000 Maleimide sodium. Grades: 95%. | |
| DSPE-PEG-NHS | 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol with active succinimidyl ester (DSPE-PEG-NHS) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an active ester group. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. Alternative Names: Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-[3-[[5-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,5-dioxopentyl]amino]propoxy]-; 3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine. CAS No. 1244955-19-8. Molecular formula: (C2H4O)nC54H98N3O15P. | |
| DT-061 | DT-061 is orally bioavailable activator of protein phosphatase 2A (PP2A). PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Alternative Names: SMAP. CAS No. 1809427-19-7. Molecular formula: C25H23F3N2O5S. Mole weight: 520.52. | |
| D-Theanine | D-Theanine, a prominent amino acid derivative abundant in tea leaves, is renowned for its calming properties that can unwind the mind and body. As a dietary supplement, it is typically used to mitigate stress and anxiety, fostering a sense of relaxation. Research has also indicated its capacity to enhance cognitive functions and alleviate depressive symptoms, suggesting that it holds potential as a multipurpose supplement. Alternative Names: H-D-Gln(Et)-OH. CAS No. 5822-62-8. Molecular formula: C7H14N2O3. Mole weight: 174.20. | |
| D-Thr(6)-Octreotide Acetate | D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-,cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI). Grades: 95%. CAS No. 87759-90-8. Molecular formula: C49H66N10O10S2.xC2H4O2. | |
| D-Trp(25)-Semaglutide | D-Trp(25)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-Trp-25-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Tyr(13)-Semaglutide | D-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-[Tyr]-13-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| (±)-Duloxetine-[d3] hydrochloride | (±)-Duloxetine-[d3] hydrochloride is the labelled impurity of Duloxetine. Duloxetine is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. Alternative Names: Duloxetine-D3 HCl; N-(Methyl-d3)-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (±)-Duloxetine-D3 HCl; N-(Methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride; N-(Methyl-d3)-3-(1-naphthoxy)-3-(2-thienyl)propylamine; (±)-Duloxetine-d3 hydrochloride. Grades: 95% by HPLC; 98% atom D. CAS No. 1188266-11-6. Molecular formula: C18H16D3NOS.HCl. Mole weight: 336.89. | |
| Duloxetine Related Compound H | Duloxetine Related Compound H is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Alternative Names: (S)-Duloxetine Succinamide; 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid. Grades: 98%. CAS No. 199191-66-7. Molecular formula: C22H23NO4S. Mole weight: 397.49. | |
| Dunnianol | Dunnianol isolated from the fruits of Illicium fargesii. Alternative Names: 5,5',5''-Triallyl-1,1':3',1''-terphenyl-2,2',2''-triol; Dunnial. Grades: 98%. CAS No. 139726-29-7. Molecular formula: C27H26O3. Mole weight: 398.5. | |
| Duocarmycin analog | Duocarmycin analog has cytotoxicity for solid tumor cells that can be used for antibody-drug conjugates (ADCs). Duocarmycins and the analogs acts via binding to the minor groove of DNA and alkylating the nucleobase adenine at the N3 position, which leads to DNA damage and cancer cell death. | |
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