BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Gabapentin Impurity 3 | Gabapentin Impurity 3 is a chemical with potential use for biochemical research, especially in the field of neurobiology. It is Gabapentin intermediate. Alternative Names: 3,3-Pentamethyleneglutarimide; 1,1-Cyclohexane diacetimide; 3,3-Pentamethylene Glutarimide; 2,4-Dioxo-3-azaspiro[5.5]undecane; 1,1-Cyclohexanediacetimide; 3-Azaspiro[5.5]undecane-2,4-dione; NSC 400093. Grades: > 95%. CAS No. 1130-32-1. Molecular formula: C10H15NO2. Mole weight: 181.24. |  |
| Gaboxadol hydrochloride | THIP hydrochloride is a GABAA receptor agonist and GABAA-ρ receptor antagonist. THIP exhibits antinociceptive, anticonvulsant and sedative effects. It is used as a hypnotic agent for the treatment of patients with insomnia. Uses: Hypnotic. Alternative Names: THIP hydrochloride; Gaboxadol HCl. Grades: ≥ 98 % by HPLC. CAS No. 85118-33-8. Molecular formula: C6H8N2O2 · HCl. Mole weight: 176.60. | |
| Galanolactone | Galanolactone is a natural diterpenoid found in the rhizomes of Zingiber officinale Roscoe. It has anti-5-HT effect with a pIC50 value 4.93. Galanolactone also has some anti-tumor effect and antifungal activity. Uses: Anti-tumor; antifungal. Alternative Names: 8,17-Epoxy-12-labden-16,15-olide. Grades: >98%. CAS No. 115753-79-2. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| Galantamine Hydrobromide EP Impurity E | Galantamine Hydrobromide EP Impurity E. CAS No. 41303-74-6. | |
| Galanthamine | Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Alternative Names: NSC 100058; NSC100058; NSC-100058; BRN 0093736; BRN0093736; BRN-0093736; Galantamine; Reminyl; Lycoremine; (-)-Galanthamine; Galantamin; Lycoremin; Jilkon; Nivalin; Razadyne; Galantamina; Galanthaminum; Galantaminum; Razadyne ER; Galantaminum. Grades: >98%. CAS No. 357-70-0. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
| Galeopsin | Galeopsin is extracted from the aerial parts of Leonurus heterophyllus SW. It could inhibit pro-inflammatory cytokine TNF-α. It has potential anti-proliferative effect and anti-inflammatory activity on several cancer cell lines. Alternative Names: (3R,8aβ)-3α-Acetoxy-4-[2-(3-furyl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-4β-hydroxy-3,4aα,8,8-tetramethylnaphthalen-2(1H)-one; [(1S,2R,4aS,8aS)-1-[2-(furan-3-yl)ethyl]-1-hydroxy-2,5,5,8a-tetramethyl-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalen-2-yl] acetate. Grades: 97.5%. CAS No. 76475-16-6. Molecular formula: C22H32O5. Mole weight: 376.49. | |
| (-)-Gallocatechin | (-)-Gallocatechin had been shown to have moderate affinity to the human cannabinoid receptor. Alternative Names: (2S,3R)-2-(3,4,5-Trihydroxyphenyl)chroman-3,5,7-triol; (2S,3R)-gallocatechin; ent-gallocatechin. Grades: >98%. CAS No. 3371-27-5. Molecular formula: C15H14O7. Mole weight: 306.27. | |
| Galloylpaeoniflorin | 6'-O-Galloylpaeoniflorin is a natural monoterpenoid compound isolated from the roots of Paeonia lactiflora Pall. 6'-O-Galloylpaeoniflorin exhibits strong androgen receptor (AR) binding activity. Alternative Names: β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate); β-D-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate), [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-; 6'-O-Galloyl paeoniflorin; ((2R,3S,4S,5R,6S)-6-(((1aR,1a1S,2R,3aR,5S,5aR)-1a1-((Benzoyloxy)methyl)-2-hydroxy-5-methyltetrahydro-1H-3,4-dioxa-2,5-methanocyclobuta[cd]pentalen-5a(5H)-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3,4,5-trihydroxybenzoate. Grades: >98%. CAS No. 122965-41-7. Molecular formula: C30H32O15. Mole weight: 632.57. | |
| Gambogenic acid | Gambogenic Acid is a natural compound isolated from Garcinia hanburyi Hook. f. It shows anticancer activity. Grades: 98%. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.8. | |
| Gambogic acid | Gambogic acid is a natural product inhibitor of Hsp90. Alternative Names: B-Guttiferrin; Beta-Guttiferrin; Beta-Guttilactone; Cambogic acid; Guttatic acid; Guttic acid. Grades: >95%. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.76. | |
| gamma-fagarine | γ-Fagarine is a natural compound extracted from Phellodendron chinense. Alternative Names: 8-Methoxydictamnine; gamma-Fagarine. Grades: 98%. (NMR). CAS No. 524-15-2. Molecular formula: C13H11NO3. Mole weight: 229.23. | |
| Ganciclovir EP Impurity C | Ganciclovir EP Impurity C is an Impurity of Ganciclovir. It is a sugar modified acyclic analogue of guanosine. It has potential to exhibit virucidal activity. Alternative Names: 2'-Monodehydroxy-2'-chloro Ganciclovir; 9-[[2-Chloro-1-(hydroxymethyl)ethoxy]methyl]guanine; 2-Amino-9-[[2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one. Grades: > 95%. CAS No. 108436-36-8. Molecular formula: C9H12ClN5O3. Mole weight: 273.68. | |
| Ganciclovir EP Impurity E | Iso Ganciclovir is an impurity of the anti-viral Gangiclovir. Uses: Antiviral agents. Alternative Names: Iso Ganciclovir; Isoganciclovir; iso-Ganciclovir; 2-Amino-9-[(2,3-dihydroxypropoxy)methyl]-1,9-dihydro-6H-purin-6-one; ((RS)-2-Amino-9-(2,3-dihydroxy-propoxymethyl)-1,9-dihydro-purin-6-one); Ganciclovir Related Compound A (USP). Grades: 98%. CAS No. 86357-09-7. Molecular formula: C9H13N5O4. Mole weight: 255.23. | |
| Ganciclovir Monopropionate | Ganciclovir Monopropionate is a potential prodrug of Ganciclovir. It was also found to exhibit anti-viral activity through experimental studies. Alternative Names: Ganciclovir Mono-O-propionate; Ganciclovir Impurity B; 2-Amino-1,9-dihydro-9-[[1-(hydroxymethyl)-2-(1-oxopropoxy)ethoxy]methyl]-6H-purin-6-one. Grades: > 95%. CAS No. 194159-18-7. Molecular formula: C12H17N5O5. Mole weight: 311.30. | |
| Ganoderal A | Ganoderal A is a natural triterpenoid compound found in several plants. Alternative Names: (24E)-3-Oxo-5α-lanosta-7,9(11),24-trien-26-al;(24E)-3-Oxo-5α-lanosta-7,9(11),24-triene-26-al;(24E)-3-Oxolanosta-7,9(11),24-trien-26-al. Grades: >95%. CAS No. 104700-98-3. Molecular formula: C30H44O2. Mole weight: 436.669. | |
| Ganoderenic acid D | Ganoderenic acid D was most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively. Grades: >98%. CAS No. 100665-43-8. Molecular formula: C30H40O7. | |
| Ganoderenic acid E | Ganoderenic acid E is a natural compound derived from Ganoderma lucidum that exhibits anticancer and anti-inflammatory properties. It has been shown to inhibit the growth of various cancer cells and reduce inflammation in experimental models. Grades: >98%. CAS No. 110241-23-1. Molecular formula: C30H40O8. Mole weight: 528.642. | |
| Ganoderic acid C2 | Ganoderic acid C2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Ganoderic Acid C2 exhibits inhibitory effect on tumor and inflammations. Alternative Names: Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,7β,15α,25R)-; (3β,7β,15α,25R)-3,7,15-Trihydroxy-11,23-dioxolanost-8-en-26-oic acid; Ganoderic acid C 2; (2R,6R)-2-methyl-4-oxo-6-((3S,5R,7S,10S,13R,14R,15S,17R)-3,7,15-trihydroxy-4,4,10,13,14-pentamethyl-11-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)heptanoic acid. Grades: >98%. CAS No. 103773-62-2. Molecular formula: C30H46O7. Mole weight: 518.68. | |
| Ganoderic acid D | Ganoderic acid D (GAD) is one of the major components in Ganoderma triterpenes. GAD treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with an IC(50) value of 17.3 +/- 0.3 microM. Alternative Names: Ganoderic Acid D; 108340-60-9; GanodericacidD; Ganodernic acid D; SCHEMBL3676373; CHEMBL2205002; HY-N1511; BDBM50021402; AKOS032946021; MS-29559; CS-0017054; (6R)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 108340-60-9. Molecular formula: C30H42O7. Mole weight: 514.6. | |
| Ganoderic acid E | Ganoderic acid E, an organic natural compound, emanates from Ganoderma lucidum, a fungus. Well-recognized for its remarkable anti-inflammatory attributes, it constitutes a crucial constituent in the research of chronic inflammatory ailments encompassing arthritand asthma. Grades: >98%. CAS No. 98665-14-6. Molecular formula: C30H40O7. Mole weight: 512.63. | |
| Ganoderic acid G | Ganoderic acid G is an exquisite natural compound extracted from Ganoderma lucidum,mainly used for studying hepatic ailments, neoplastic disorders and inflammatory responses. This intriguing molecule has remarkable attributes encompassing potent antioxidative and anti-cancerous actions. Alternative Names: (3beta,7beta,12beta)-3,7,12-trihydroxy-11,15,23-trioxolanost-8-en-26-oic acid. Grades: >98%. CAS No. 98665-22-6. Molecular formula: C30H44O8. | |
| Ganoderic acid S | Ganoderic acid S is a triterpenoid. Alternative Names: (24E)-3-Oxo-5alpha-lanosta-7,9(11),24-trien-26-oic acid. CAS No. 104759-35-5. Molecular formula: C30H44O3. Mole weight: 452.7. | |
| Ganoderiol F | Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 were found in early stages of Ganoderiol F treatment and were presumed to cause cell-cycle arrest and trigger premature senescence of HepG2 cells; suggests that the growth-arrest and senescence induction capability on cancer cells suggest anticancer potential of Ganoderiol F. It could be developed further as both anti-HIV and antimalaria.In Compared to plasmepsin I, ganoderiol-F is higher towards HIV-1 protease. Uses: Anti-inflammatory; anti-hiv. Alternative Names: 26,27-Dihydroxylanosta-7,9(11),24-trien-3-one. Grades: >98%. CAS No. 114567-47-4. Molecular formula: C30H46O3. Mole weight: 454.7. | |
| Ganodermanondiol | Ganodermanondiol is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Study shows that Ganodermanondiol exhibits the inhibitory effect on the proliferation of HL60 and K562 human tumor cells. Alternative Names: (5R,10S,13R,14R,17R)-17-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one. Grades: >98%. CAS No. 107900-76-5. Molecular formula: C30H48O3. Mole weight: 456.711. | |
| Ganoderol A | Ganoderol A,a natural triterpenoid found in the fruiting body of Ganoderma lucidum, has the activity of anti-inflammatory and protection against UVA damage, these founctions show that ganoderol A is a candidate for the development of a suitable product to protect skin from UV-induced photoaging. Ganoderol A exhibits potent inhibitory activity against angiotensin converting enzyme activity. Via conversion of acetate or mevalonate as a precursor of the compound, ganoderal A exhibits potent inhibitory activity against cholesterol biosynthesis. Uses: Anti-inflammatory. Alternative Names: Ganodermenonol. Grades: >97%. CAS No. 104700-97-2. Molecular formula: C30H46O2. Mole weight: 438.7. | |
| Ganoderol B | Ganoderol B also called ganodermadiol is a natural triterpenoid found in the fruiting body of Ganoderma lucidum, it is an angiotensin-converting enzyme inhibitor and is a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum. Ganoderol B exhibits the activity of anti-androgen. Uses: Anti-androgen. Alternative Names: (3beta,24E)-Lanosta-7,9(11),24-trien-3,26-diol;ganodermadiol;(24E)-5α-Lanosta-7,9(11), 24-triene-3β,26-diol. Grades: >98%. CAS No. 104700-96-1. Molecular formula: C30H48O2. Mole weight: 440.7. | |
| Gap19 (TFA) | Gap19 (TFA). | |
| Garbanzol | Garbanzol, a revolutionary therapeutic agent with mighty anti-inflammatory properties, proffers a potential cure for a myriad of inflammatory ailments. Counted among them are rheumatoid arthritis, psoriasis, and inflammatory bowel disease. By constraining vital enzymes linked with inflammation, Garbanzol governs the synthesis of pro-inflammatory cytokines. Encouragingly, clinical trials demonstrate an encouraging safety profile, and an exceptional tolerance capacity. Alternative Names: (2R-trans)-3,4',7-Trihydroxyflavanone. Grades: 98%. CAS No. 1226-22-8. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Garcinone C | Garcinone C is isolated from the fruits of Garcinia mangostana. It is the most potent inhibitor of AChE, and it exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines. Alternative Names: Garcinone-C; 9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-8-(3-hydroxy-3-Methylbutyl)-2-(3-Methyl-2-buten-1-yl)-. Grades: 95%. CAS No. 76996-27-5. Molecular formula: C23H26O7. Mole weight: 414.45. | |
| Garcinone D | Garcinone D usually comes from the fruits of Garcinia mangostana. It inhibited p65 activation with IC50 values of 3.2 microg/ml. Alternative Names: 1,3,6-Trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one. Grades: 98%. CAS No. 107390-08-9. Molecular formula: C24H28O7. Mole weight: 428.48. | |
| Gardenin B | Gardenin B is a natural flavonoid compound found in several plants. Alternative Names: 4',6,7,8-Tetramethoxy-5-hydroxyflavone; 5-Hydroxy-4',6,7,8-tetramethoxyflavone; 5-O-Desmethyltangeretin; 5-DesMethyltangeretin; 5-O-DeMethyltangeretin; Demethyltangeretin. Grades: >98%. CAS No. 2798-20-1. Molecular formula: C19H18O7. Mole weight: 358.342. | |
| Gardiquimod | Gardiquimod is a small-molecule agonist of TLR7. It induces the activation of NF-κB in HEK 293 cells expressing TLR7. Uses: Toll-like receptor agonists. Alternative Names: 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-[(ethylamino)methyl]-α,α-dimethyl-; 4-Amino-2-[(ethylamino)methyl]-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol. Grades: ≥98% (HPLC). CAS No. 1020412-43-4. Molecular formula: C17H23N5O. Mole weight: 313.40. | |
| Gardneramine | Gardneramine is an indole alkaloid isolated from the roots of Gardneria multiflora Makino, which displays a local anesthetic effect. Alternative Names: 1,2-Didehydro-2-deoxo-17-deoxy-2,17-epoxygardneramine oxindole. Grades: 95.0%. CAS No. 34274-91-4. Molecular formula: C23H28N2O5. Mole weight: 412.486. | |
| Gardoside | Gardoside is found in the fruits of Gardenia jasminoides. Alternative Names: Gardoside; 54835-76-6; (1S,4aS,6S,7aS)-6-hydroxy-7-methylidene-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid; CHEMBL3622810; CHEBI:80827. Grades: > 95%. CAS No. 54835-76-6. Molecular formula: C16H22O10. Mole weight: 374.34. | |
| Gartanin | Gartanin is isolated from the stem bark of Garcinia mangostana. It could be a multiple targeting agent into its chemopreventive properties for human urinary bladder cancer. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells. Uses: Antifungal property; antioxidant, anti - inflammatory properties; antineoplastic property. Alternative Names: 1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9H-xanthen-9-one. Grades: 98%. CAS No. 33390-42-0. Molecular formula: C23H24O6. Mole weight: 396.43. | |
| Gatifloxacin USP Related Compound E | Iso-Gatifloxacin, an antibiotic of the fluoroquinolone class, exhibits potent activity against a wide range of bacterial infections. It stands as a crucial weapon against susceptible strains of Gram-positive and Gram-negative bacteria. Alternative Names: Iso-Gatifloxacin; Isogatifloxacin; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(2-Methyl-1-piperazinyl)-4-oxo-. Grades: 95%. CAS No. 1029364-65-5. Molecular formula: C19H22FN3O4. Mole weight: 375.40. | |
| GDC-0084 | GDC-0084, a PI3K inhibitor, has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. It was just licensed to Novogen and start a Phase II trial for Glioma. Uses: Gdc-0084 is a pi3k inhibitor that has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. Alternative Names: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084; 5-(6,6-dimethyl-4-morpholin-4-yl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl)pyrimidin-2-amine. Grades: 98%. CAS No. 1382979-44-3. Molecular formula: C18H22N8O2. Mole weight: 382.19. | |
| GDC-0152 | GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic GDC-0152 binds to the Smac binding groove on IAPs, including the direct caspase inhibitor X chromosome-linked IAP (XIAP) and the cellular IAPs 1 and 2, which may inhibit their activities and promote the induction of apoptosis through apoptotic signaling pathways. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding to and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains. Smac, the endogenous IAP antagonist, relies on its N-terminal four amino-acid motif for binding to IAPs. Alternative Names: GDC-0152; GDC0152; GDC 0152. CAS No. 873652-48-3. Molecular formula: C25H34N6O3S. Mole weight: 498.646. | |
| GDC0941 | GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K that inhibits p110α, β, δ, and γ with IC50 values of 3, 33, 3, and 75 nM. Alternative Names: 4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine; GDC-0941; GDC 0941; GDC0941; RG7321; RG-7321; RG 7321; GNE0941; GNE-0941; GNE 0941; Pictrelisib; Pictilisib. CAS No. 957054-30-7. Molecular formula: C23H27N7O3S2. Mole weight: 513.635. | |
| Gedunin | Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Grades: >98%. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57. | |
| Gefapixant | Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. It is under a clinical trial for the treatment of chronic cough. Alternative Names: AF-219; MK-7264. CAS No. 1015787-98-0. Molecular formula: C14H19N5O4S. Mole weight: 353.4. | |
| Gefitinib-[d6] | One of the isotopic labelled form of Gefitinib, which could be used as an antineoplastic agent. Alternative Names: Gefitinib-d6; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine-d6; Iressa-d6. CAS No. 1228664-49-0. Molecular formula: C22H18ClFN4O3D6. Mole weight: 452.95. | |
| Gefitinib Impurity II | Gefitinib Impurity II. Alternative Names: N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine. Grades: > 95%. CAS No. 153437-78-6. Molecular formula: C16H13ClFN3O2. Mole weight: 333.75. | |
| Geissoschizine methyl ether | Geissoschizine methyl ether is an indole alkaloid isolated from Uncariae hooks. Geissoschizine methyl ether acts as a 5-HT7 receptor antagonist and also a potent acetylcholinesterase (AChE) inhibitor. Alternative Names: Methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate. Grades: 98.0%. CAS No. 60314-89-8. Molecular formula: C22H26N2O3. Mole weight: 366.461. | |
| Gelomulide A | Gelomulide A is isolated from Suregada. Alternative Names: (3β,5β,9β,10α,12β,14β)-16-Oxo-8,14:12,16-diepoxyabiet-13(15)-en-3-yl acetate. Grades: 98%. CAS No. 122537-59-1. Molecular formula: C22H30O5. Mole weight: 374.471. | |
| Gelomulide B | Gelomulide B is a diterpenoid found in Suregada multiflora. Alternative Names: (3S,4aS,6aS,7aR,10aS,11aS,11bR,11cR)-4,4,8,11c-tetramethyl-9-oxo-1,2,3,4,4a,5,6,7a,9,11a,11b,11c-dodecahydrobis(oxireno)[2',3':1,10a;2'',3'':3,4]phenanthro[3,2-b]furan-3-yl acetate. Grades: 97.5%. CAS No. 122537-60-4. Molecular formula: C22H28O6. Mole weight: 388.454. | |
| Gelomulide N | Gelomulide N also called 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide, is a natural diterpenoid compound. Alternative Names: 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide;1-epi-Gelomulide O. Grades: >97%. CAS No. 1005212-02-1. Molecular formula: C24H32O7. Mole weight: 432.51. | |
| Gemcabene | Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Alternative Names: 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid; gemcabene; 6,6'-oxybis(2,2-dimethylhexanoic acid); PD72953; PD 72953; PD-72953. Grades: >98%. CAS No. 183293-82-5. Molecular formula: C16H30O5. Mole weight: 302.41. | |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Alternative Names: CO-101; CO101; CO 101; CP-4126; CP4126; CP 4126. CAS No. 210829-30-4. Molecular formula: C27H43F2N3O5. Mole weight: 527.654. | |
| Geniposidic acid | Geniposidic acid is a natural chemical compound, classified as an iridoid glucoside, found in a variety of plants including Eucommia ulmoides and Gardenia jasminoides, used to treat inflammation, jaundice and hepatic disorders. Alternative Names: Geniposidic acid. Grades: >98%. CAS No. 27741-01-1. Molecular formula: C16H22O10. Mole weight: 374.34. | |
| Gentianine | Gentianine is isolated from the herbs of Trigonella foenum-graecum L. Uses: Anti-diabetic effect; anti-inflammatory. Alternative Names: 3,4-Dihydro-5-vinyl-1H-pyrano[3,4-c]pyridin-1-one. Grades: 98%. CAS No. 439-89-4. Molecular formula: C10H9NO2. Mole weight: 175.2. | |
| Gentisin | Gentisin is a pigment with mutagenic activity that is isolated from the roots of Gentiana lutea. Alternative Names: Gentianin; 1,7-Dihydroxy-3-methoxyxanthone; 1,7-Dihydroxy-3-methoxyxanthen-9-one. Grades: 98.0%. CAS No. 437-50-3. Molecular formula: C14H10O5. Mole weight: 258.229. | |
| Germanium(II) selenide | Germanium(II) selenide, a widely-used semiconductor material in the optoelectronics industry, presents immense potential in thin film solar cell production and acts as a primary source of germanium and selenium for medical purposes, namely drug delivery and cancer treatments. Alternative Names: Germanium(II) selenide; Germanium selenide (GeSe, 5N). Grades: 95%. CAS No. 12065-10-0. Molecular formula: GeSe. Mole weight: 151.6. | |
| GGTI-2418 | GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways. GGTase I catalyzes the lipid posttranslational modification which is required for the function of Rho GTPases (frequently found aberrantly activated in human cancer). GGTase I inhibitors block Rho function in cancer cells and induce a G1 phase cell cycle arrest by a mechanism involving induction of the CDK inhibitors p21waf and p27kip, CDK2 and CDK4 inhibition and hypophoshorylation of the tumor suppressor Rb. GGTase I inhibitors also induce apoptosis by a mechanism involving downregulation of the expression of survivin and suppression of the activation of PI3K/Akt. Alternative Names: GGTI 2418; GGTI-2418; GGTI 2418. CAS No. 501010-06-6. Molecular formula: C23H31N5O4. Mole weight: 441.532. | |
| GGTI-298 | GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Alternative Names: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate; GGTI 298; GGTI298; GGTI-298; N-4-[2(R)-Amino-3-mercaptopropyl]amino-2-naphthylbenzoyl-(L)-Leucine methyl ester, TFA; (S)-methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate. CAS No. 180977-44-0. Molecular formula: C27H33N3O3S. Mole weight: 479.63. | |
| Giffonin R | Giffonin R is a natural compound isolated from the herbs of Corylus avellana. Grades: 97.5%. CAS No. 1966183-72-1. Molecular formula: C19H16O3. Mole weight: 292.334. | |
| Gilteritinib | Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations. In invitro, among the 78 tyrosine kinases tested, ASP2215 inhibited FLT3, LTK, ALK, and AXL kinases by over 50% at 1 nM with an IC50 value of 0.29 nM for FLT3, approximately 800-fold more potent than for c-KIT, the inhibition of which is linked to a potential risk of myelosuppression. ASP2215 inhibited the growth of MV4-11 cells, which harbor FLT3-ITD, with an IC50 value of 0.92 nM, accompanied with inhibition of pFLT3, pAKT, pSTAT5, pERK, and pS6. ASP2215 decreased tumor burden in bone marrow and prolonged the survival of mice intravenously transplanted with MV4-11 cells. ASP2215 may have potential use in treating AML. Alternative Names: ASP2215; ASP-2215; ASP 2215; Xospata; Gilteritinibum; 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide. Grades: ≥95%. CAS No. 1254053-43-4. Molecular formula: C29H44N8O3. Mole weight: 552.71. | |
| Ginkgolide A | Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM. Alternative Names: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-; [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; Bilobalide A; BN 52020. Grades: >98%. CAS No. 15291-75-5. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Ginkgolide B | Ginkgolide B is a PAFR antagonist with an IC50 of 3.6 μM. Ginkgolide B is a bioactive diterpenoid trilactone derived from Ginkgo biloba leaves, known for its potent platelet-activating factor (PAF) antagonism. It has a complex structure with multiple chiral centers and exhibits significant neuroprotective and cerebrovascular benefits. These properties make it a promising candidate for treating neurodegenerative diseases, inflammation, and conditions related to cerebral blood flow. Uses: Fibrinolytic agents. Alternative Names: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,8-hexahydroxy-α3-methyl-, tri-γ-lactone; Ginkgolide A, 1-hydroxy-, (1β)-; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11β,11aR*)]-; Bilobalide B; BN 52021; BN 52051; Ginkgolides, ginkgolide B. Grades: >98%. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.40. | |
| Ginkgolide C | Ginkgolide C is a bioactive diterpenoid trilactone compound derived from the leaves of the Ginkgo biloba tree. Similar to its counterparts Ginkgolide A and Ginkgolide B, it is characterized by its unique trilactone structure with multiple chiral centers, contributing to its diverse pharmacological properties. Ginkgolide C is known for its potent antagonistic effects on platelet-activating factor (PAF), making it a promising candidate for treating inflammatory and allergic conditions. Additionally, it has been studied for its neuroprotective effects, particularly in the context of neurodegenerative diseases and cerebral ischemia. Alternative Names: (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,7,8-heptahydroxy-α3-methyl-, tri-γ-lactone; Ginkgolide A, 1,7-dihydroxy-, (1β,7β)-; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-, [1R-(1α,2α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11α,11aR*)]-; BN 52022. Grades: >98%. CAS No. 15291-76-6. Molecular formula: C20H24O11. | |
| Ginkgolide J | Ginkgolide J is extracted from the seed of Ginkgo biloba L. It reduces apoptotic damage in cultured chick embryonic neurons. It contributes to the antioxidant properties of G. biloba. It has the superoxide scavenging effect and neuroprotective effect. Alternative Names: 7beta-hydroxyginkgolide a; BN 52024; GinkgolideA, 7-hydroxy-, (7β)-; J Ginkgoli. Grades: >98%. CAS No. 107438-79-9. Molecular formula: C20H24O10. | |
| Ginkgolide K | Ginkgolide K is extracted from the leaves of Ginkgo biloba L. It promotes angiogenesis after ischemia stroke and promotes astrocyte migration and proliferation after oxygen-glucose deprivation. It improves nerve injury after cerebral ischemia-reperfusion and inhibits PAF-induced platelet aggregation. It also can promote the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells and shows anti- Parkinson's disease activity. It shows neuroprotective effect and anti-oxidative stress on ischemic stroke. Alternative Names: 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)-2,3,10a,11-tetrahydro-4,11-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aS,10aR,11R,11aR)-. Grades: 97.5%. CAS No. 153355-70-5. Molecular formula: C20H22O9. Mole weight: 406.38. | |
| Ginsenoside F3 | Ginsenoside F3 is extracted from the root of Panax ginseng C. A. Mey. It has immunoenhancing activity by regulating production and gene expression of type 1 cytokines and type 2 cytokines in murine spleen cells. Alternative Names: (20S)-20-(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyloxy)-5α-dammara-24-ene-3β,6α,12β-triol; 3β,6α,12β-Trihydroxy-5α-dammar-24-en-20-yl 6-O-α-L-arabinopyranosyl-β-D-glucopyranoside. Grades: >98%. CAS No. 62025-50-7. Molecular formula: C41H70O13. | |
| Ginsenoside F4 | Ginsenoside F4 is extracted from the root of Panax ginseng C. A. Mey. It has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis. It was found to strongly inhibit activation of p38 mitogen-activated protein kinase in signal transduction pathways. Alternative Names: Ginsenoside Rg6; (20E)-Ginsenoside F4. Grades: >98%. CAS No. 181225-33-2. Molecular formula: C42H70O12. Mole weight: 767. | |
| Ginsenoside F5 | Ginsenoside F5 is extracted from the root of Panax ginseng C. A. Mey. Alternative Names: Chikusetsusaponin L8; (3beta,6alpha,12beta)-3,6,12-Trihydroxydammar-24-en-20-yl 6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 189513-26-6. Molecular formula: C41H70O13. | |
| Ginsenoside Ra1 | Ginsenoside Ra1 is a known dammarane-type triterpene saponins isolated from the root of Panax ginseng. Panax ginseng C. A. Meyer (Araliaceae) is a well-known oriental medicinal plant that has been used as a general tonic for thousands of years. Alternative Names: β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(O-β-D-xylopyranosyl-(1→4)-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-; (3β,12β)-12-Hydroxy-20-[(O-β-D-xylopyranosyl-(1→4)-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside; Dammarane, β-D-glucopyranoside deriv. Grades: > 98%. CAS No. 83459-41-0. Molecular formula: C58H98O26. Mole weight: 1211.38. | |
| Ginsenoside Ra2 | Ginsenoside Ra2 is a known ginsenoside isolated from the root of Panax ginseng. Previous phytochemical studies on P. ginseng led to the isolation of ginsenosides (triterpenoid saponin glycosides), polyacetylenes, sesquiterpenoids, flavonoids, and polysaccharides. Alternative Names: β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(O-β-D-xylopyranosyl-(1→2)-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-; (3β,12β)-12-Hydroxy-20-[(O-β-D-xylopyranosyl-(1→2)-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside; Dammarane, β-D-glucopyranoside deriv. Grades: > 98%. CAS No. 83459-42-1. Molecular formula: C58H98O26. Mole weight: 1211.38. | |
| Ginsenoside Ra3 | Ginsenoside Ra3 is isolated from the root of Panax ginseng. Protopanaxadiol- and protopanaxatriol-type ginsenosides are the major biologically active components of P. ginseng that contribute to its diverse pharmacological effects on the central nervous system, cardiovascular system, endocrine secretion, immune-modulation, metabolism, stress, aging, and cancer. Alternative Names: β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(O-β-D-xylopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-; (3β,12β)-12-Hydroxy-20-[(O-β-D-xylopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside; Dammarane, β-D-glucopyranoside deriv. Grades: > 98%. CAS No. 90985-77-6. Molecular formula: C59H100O27. Mole weight: 1241.41. | |
| Ginsenoside Rh7 | Ginsenoside Rh7 is a new dammarane-type triterpene saponins from the Leaves of Panax ginseng. Panax ginseng is an ancient and famous herbal drug in traditional chinese medicines. Bioactive saponins from natural medicines, a number of dammarane-type triterpene oligoglycosides were found to have anti-cancer, anti-arrhythmia and inhibitory effects on reducing sideeffects of steroid hormones. Alternative Names: β-D-Glucopyranoside, (3β,7β,12β)-3,7,12-trihydroxydammara-5,24-dien-20-yl; (3β,7β,12β)-3,7,12-Trihydroxydammara-5,24-dien-20-yl β-D-glucopyranoside. Grades: > 98%. CAS No. 343780-68-7. Molecular formula: C36H60O9. Mole weight: 636.86. | |
| GIT 27 | GIT 27 is an orally active immunomodulatory agent. It inhibits TNF-α secretion via interference of macrophage TLR4 and TLR 2/6 signaling pathway. Alternative Names: 5-Dihydro-3-phenyl-5-isoxazoleacetic acid; (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid; 3-phenyl-4,5-dihydro-5-isoxazole acetic acid; VGX-1027; VGX 1027; VGX1027; GIT 27; GIT-27; GIT27. CAS No. 6501-72-0. Molecular formula: C11H11NO3. Mole weight: 205.21. | |
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