BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Humantenidine | Humantenidine is a natural alkaloid found in the herbs of Gelsemium sempervirens. Alternative Names: 14-Hydroxygelsenicine. Grades: >97%. CAS No. 114027-39-3. Molecular formula: C19H22N2O4. Mole weight: 342.4. |  |
| Humantenirine | Humantenirine is an alkaloid isolated from Gelsemium sempervirens. Alternative Names: Humantenine, 4-demethyl-11-methoxy-; (3S,3'Z,4'S,4a'S,7'S,9a'S)-3'-ethylidene-1,6-dimethoxy-1',2',3',4',4a',5',9',9a'-octahydro-7'H-spiro[indole-3,8'-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one. Grades: 96.5%. CAS No. 82375-30-2. Molecular formula: C21H26N2O4. Mole weight: 370.449. | |
| Humantenmine | Humantenmine, isolated from Gelsemium elegans Benth, may inhibit several CYP450 enzyme activities. Alternative Names: Spiro[3H-indole-3,7'(6'H)-[3,6]methano[3H]oxepino[4,3-b]pyrrol]-2(1H)-one, 2'-ethyl-3'a,4',8',8'a-tetrahydro-1-methoxy-, (3S,3'R,3'aS,6'R,8'aS)-. Grades: >98%. CAS No. 82354-38-9. Molecular formula: C19H22N2O3. Mole weight: 326.39. | |
| Hupehemonoside | Hupehemonoside is found in Fritillaria pallidiflora. Alternative Names: Imperialine 3-beta-D-glucoside; Sipeimine-3-β-D-glucoside. Grades: > 95%. CAS No. 67968-40-5. Molecular formula: C33H53NO8. Mole weight: 591.77. | |
| Hupehenine | Hupehenine is isolated from Fritillaria thunbergii Miq. Alternative Names: Cevane-3,6-diol(3β,5α,6β,17β). Grades: >98%. CAS No. 98243-57-3. Molecular formula: C27H45NO2. Mole weight: 415.65. | |
| hVEGF-IN-1 | hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity. Tumor bearing mice treated with hVEGF-IN-1 have an average tumor volume of less than 300 mm. The tumor weight in the presence of hVEGF-IN-1 reduces around 60.1% to a final weight of 0.18 g. No significant change in body weight is observed during the treatment. Alternative Names: 1-Piperazinepropanamide, N-[2-[4-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-2-quinazolinyl]phenyl]-4-methyl. CAS No. 1637443-98-1. Molecular formula: C34H43N7O2. Mole weight: 581.75. | |
| HY-17542 | HY-17542 is a potent inhibitor of papain-like protease (PLpro) with IC50 of 2.6 μM. Alternative Names: PLpro inhibitor 6; (R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide; HY 17542; HY17542. Grades: >98%. CAS No. 1093070-14-4. Molecular formula: C22H22N2O2. Mole weight: 346.43. | |
| Hybridaphniphylline A | Hybridaphniphylline A isolated from daphniphyllum. Uses: Standardized herbal extract. Alternative Names: (1S,1aR,3S,3aS,3a1S,5aS,7aR,7bR,9aS,12S,13R,14aR,14bS,14cR)-4-(hydroxymethyl)-12,14b-dimethyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,1a,3,3a,3a1,5a,8,9,9a,10,11,12,13,14,14a,14b,15,16-o. Grades: 95%. CAS No. 1467083-07-3. Molecular formula: C37H47NO11. Mole weight: 681.77. | |
| Hybridaphniphylline B | Hybridaphniphylline B, a naturally occurring product, has shown considerable potential as an immunomodulatory agent. It has been extensively studied for its anti-inflammatory and analgesic properties, with growing interest in its potential efficacy in treating various inflammatory and chronic pain conditions. Despite its proven therapeutic potential, the precise mechanism of action of Hybridaphniphylline B is still under investigation, and further research is necessary to fully understand its pharmacological properties. This remarkable natural product holds great promise for the development of novel therapeutic interventions that can improve the lives of people suffering from chronic inflammatory disorders. Alternative Names: 5,14a:11,12c-Dimethano-15H-4,16-dioxa-8a-azabenzo[a]cyclopent[1',7']indeno[3'a,4':4,5]indeno[7,1-gh]azulene-15,18-dione, 3-(β-D-glucopyranosyloxy)-2a,3,4a,5,6,7,7a,8,9,10,11,12,12a,12b,13,14,16a,16b-octadecahydro-2-(hydroxymethyl)-10,12b-dimethyl-, (2aS,3S,4aR,5R,7aS,8aS,10S,11R,12aR,12bS,12cR,14aS. Grades: 98%. CAS No. 1467083-09-5. Molecular formula: C37H47NO11. Mole weight: 681.78. | |
| Hydramicromelin B | Hydramicromelin B is a coumarin isolated from the aerial parts of Micromelum integerrimum. Alternative Names: 6-[(2R,3R,4S)-3,4-dihydroxy-4-methyl-5-oxooxolan-2-yl]-7-methoxychromen-2-one. Grades: 97.5%. CAS No. 369391-55-9. Molecular formula: C15H14O7. Mole weight: 306.27. | |
| Hydramicromelin D | Hydramicromelin D is a coumarin isolated from the twigs of Micromelum integerrimum. Alternative Names: 6-[(2R,3S,4S)-3,4-dihydroxy-4-methyl-5-oxooxolan-2-yl]-7-methoxychromen-2-one. Grades: 98.0%. CAS No. 1623437-86-4. Molecular formula: C15H14O7. Mole weight: 306.27. | |
| Hydrangenol | Hydrangenol is isolated from the herbs of Hydrangea hortensia. Uses: Antiallergic. Alternative Names: 3-(4-Hydroxyphenyl)-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one. Grades: 98.5%. CAS No. 480-47-7. Molecular formula: C15H12O4. Mole weight: 256.3. | |
| Hydrangetin | Hydrangetin is a coumarin isolated from the rhizome of Daphne papyracea var. crassiuscula. Alternative Names: 7-Hydroxy-8-methoxycoumarin; 2H-1-Benzopyran-2-one, 7-hydroxy-8-methoxy-. Grades: 98.5%. CAS No. 485-90-5. Molecular formula: C10H8O4. Mole weight: 192.17. | |
| Hydrochlorothiazide EP Impurity C | An impurity of Hydrochlorothiazide, a diuretic medication used for the treatment of high blood pressure. Alternative Names: N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide ; HCTZ-CH2-HCTZ. Grades: > 95%. CAS No. 402824-96-8. Molecular formula: C15H16Cl2N6O8S4. Mole weight: 607.49. | |
| Hydrocortisone aceponate | Hydrocortisone aceponate is a corticosteroid used in form of creams for the treatment of various dermatoses (skin conditions). Alternative Names: Efficort. Grades: 95%. CAS No. 74050-20-7. Molecular formula: C26H36O7. Mole weight: 460.563. | |
| Hydroxyfasudil Hydrochloride | Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Alternative Names: HA 1100 hydrochloride; HA1100 hydrochloride; HA-1100 hydrochloride; 5-(1,4-diazepan-1-ylsulfonyl)-2~{H}-isoquinolin-1-one hydrochloride; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride. Grades: >98%. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.826. | |
| Hydroxy Itraconazole | A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. Uses: Hydroxy itraconazole is a metabolite of itraconazole and could be used as an antimycotic. Alternative Names: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 112559-91-8. Molecular formula: C35H38Cl2N8O5. Mole weight: 721.65. | |
| Hydroxy Ivabradine | An impurity of Ivabradine, a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Alternative Names: 1,3,4,5-Tetrahydro-3-(3-hydroxypropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one; 3-(3-Hydroxypropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one. Grades: > 95%. CAS No. 1235547-07-5. Molecular formula: C15H21NO4. Mole weight: 279.34. | |
| Hydroxymethyl EDOT | Hydroxymethyl EDOT (CAS# 146796-02-3 ) is a useful research chemical. Alternative Names: (2,3-Dihydrothieno[3,4-b][1,4]dioxin-2-yl)methanol; EDT-methanol. Grades: 95 %. CAS No. 146796-02-3. Molecular formula: C7H8O3S. Mole weight: 172.20. | |
| [Hydroxy(tosyloxy)iodo]benzene | [Hydroxy(tosyloxy)iodo]benzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Alternative Names: Hydroxy(4-methylbenzenesulfonato-κO)phenyliodine; Phenyliodoso hydroxide tosylate; Hydroxy(4-methylbenzenesulfonato-O)phenyliodine; Phenyliodosyl hydroxide tosylate; HTIB; Koser's reagent; [Hydroxy(4-toluenesulfonato)iodo]benzene. Grades: 98%. CAS No. 27126-76-7. Molecular formula: C13H13IO4S. Mole weight: 392.21. | |
| Hydroxytuberosone | Hydroxytuberosone is purified from the roots of Pueraria lobata. Alternative Names: Hydroxytuberosone; 95456-43-2; 1,14-dihydroxy-7,7-dimethyl-8,12,20-trioxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2(11),3,5,9,15,18-hexaen-17-one. Grades: 98.0%. CAS No. 95456-43-2. Molecular formula: C20H18O6. Mole weight: 354.36. | |
| Hyoscine Butylbromide EP Impurity G | Hyoscine Butylbromide EP Impurity G. CAS No. 92714-23-3. | |
| Hypaconine | Hypaconine, a naturally occurring alkaloid, has been extensively researched for its potential use as an agent for combating cancer. Several studies have revealed that Hypaconine effectively suppresses the proliferation of select cancer cells, thereby demonstrating its potential as a therapeutic intervention for cancer treatment. Furthermore, Hypaconine's properties have also drawn interest as a possible neuroprotective agent. The versatility of this compound, therefore, offers promising therapeutic applications in the treatment of neurodegenerative ailments. Alternative Names: Benzoylhypacoitine; (1alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methylaconitane-8,13,14,15-tetrol; 3-Deoxymesaconine. Grades: >98%. CAS No. 63238-68-6. Molecular formula: C24H39NO8. Mole weight: 469.6. | |
| Hypaconitine | Hypaconitine, a neuromuscular blocker, is a diterpene alkaloid found in the root of Aconitum carmichaelii. It is the primary constituent responsible for the neuromuscular blocking action of aconite root. It could inhibit CaM expression and Cx43 (Ser368) phosphorylation. It has anti-inflammatory effect. Uses: A neuromuscular blocker could inhibit cam expression and cx43 (ser368) phosphorylation. it has anti-inflammatory effect. Alternative Names: (1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-acetatebenzoat; 15-tetraol,16,16-trimethoxy-4-(methoxymethyl)-20-methyl-18-aconitane-14; Aconitane-8,13,14,15-tetrol,1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-,8-acetate 14-benzoate, (1α,6α,14α,15α,16β)-; (1α,6α,14α,15α,16β)1,6,16-TriMethoxy-4-(MethoxyMethyl)-20-Methylaconitane-8,13,14,15-tetrol 8-Acetate 14-Benzoate; Japaconitine B1; Deoxymesaconitine. Grades: >98%. CAS No. 6900-87-4. Molecular formula: C33H45NO10. Mole weight: 615.3. | |
| Hythiemoside A | Hythiemoside A isolated from the herb of Siegesbeckia orientalis. Alternative Names: (3α,5β,9β,10α,13α,15R)-3-(β-D-Glucopyranosyloxy)-15-hydroxypimar- 8(14)-en-16-yl acetate. Grades: 0.985. CAS No. 853267-91-1. Molecular formula: C28H46O9. Mole weight: 526.7. | |
| Hythiemoside B | Hythiemoside B is found in Siegesbeckia orientalis. Alternative Names: Hythiemoside B; 853267-90-0; HY-N8150; CS-0140208E87124. Grades: > 95%. CAS No. 853267-90-0. Molecular formula: C28H46O9. Mole weight: 526.66. | |
| HZ-1157 | HZ-1157 is an inhibitor of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) protease. Alternative Names: HZ-1157; HZ 1157; HZ1157. Dengue Virus Inhibitor II; 5-tert-butoxyquinazoline-2,4-diamine; 5-(tert-Butoxy)quinazoline-2,4-diamine; 2,4-Quinazolinediamine, 5-(1,1-dimethylethoxy)-. Grades: 98.75%. CAS No. 1009734-33-1. Molecular formula: C12H16N4O. Mole weight: 232.287. | |
| IACS-010759 | IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Alternative Names: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. Grades: ≥98%. CAS No. 1570496-34-2. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57. | |
| IAXO-102 | IAXO-102 is a TLR4 antagonist that modulates non-hematopoietic TLR4 proinflammatory signalling and inhibits experimental abdominal aortic aneurysm (AAA) development. Alternative Names: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; EX-A3691; AKOS037648519; BS-14387; HY-125171; CS-0089755; D70080; Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-|A-D-glucopyranoside. CAS No. 1115270-63-7. Molecular formula: C35H71NO5. Mole weight: 585.94. | |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Alternative Names: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. | |
| I-BET762 carboxylic acid | I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. Alternative Names: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2. CAS No. 1300019-38-8. Molecular formula: C20H17ClN4O3. Mole weight: 396.83. | |
| Ibotenic acid | Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. Alternative Names: (+/-)-Ibotenic acid; DL-Ibotenic acid. Grades: ≥98% by HPLC. CAS No. 2552-55-8. Molecular formula: C5H6N2O4. Mole weight: 158.11. | |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Alternative Names: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: 95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Alternative Names: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Alternative Names: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grades: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31. | |
| (±)-Ibuprofen-[d3] Sodium Salt | (±)-Ibuprofen-[d3] Sodium Salt is the labelled analogue of (±)-Ibuprofen Sodium salt, which could be used as a nonsteroidal anti-inflammatory. Alternative Names: (±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3); α-Methyl-4-(isobutyl)phenylacetic Acid-d3, Sodium Salt. Grades: 95% by HPLC; 98% atom D. CAS No. 1219805-09-0. Molecular formula: C13H14D3NaO2. Mole weight: 231.28. | |
| Ibuprofen lysine | Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Alternative Names: Arflamin; NeoProfen; Saren. Grades: >98%. CAS No. 57469-77-9. Molecular formula: C19H32N2O4. Mole weight: 352.47. | |
| Ibuprofen piconol | Ibuprofen piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen. It acts as a cyclooxygenase inhibitor. Alternative Names: Pimeprofen; Staderm; Vesicum; pyridin-2-ylmethyl 2-[4-(2-methylpropyl)phenyl]propanoate. CAS No. 64622-45-3. Molecular formula: C19H23NO2. Mole weight: 297.4. | |
| Icariside E5 | Icariside E5 is a lignan glycoside isolated from the herbs of Epimedium brevicornu. It has antioxidant property that strengthens the importance of peppers in the Mediterranean diet. Uses: Antioxidant property. Alternative Names: 3-[4-β-D-Glucopyranosyloxy-5-methoxy-3-[2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethyl]phenyl]-2-propen-1-ol; 2-[(2R)-1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-propanyl]-4-[(1 E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl β-D-glucopyranoside. Grades: 93%. CAS No. 126176-79-2. Molecular formula: C26H34O11. Mole weight: 522.54. | |
| Icariside I | Icariside I is extracted from the herbs of Epimedium brevicornum Maxim. Alternative Names: Icariin I. Grades: >98%. CAS No. 56725-99-6. Molecular formula: C27H30O11. Mole weight: 530.5. | |
| Icariside II | A regulator of CXCR4 expression. Uses: Ingredient of health care products. Alternative Names: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Baohuoside 1; Baohuoside I; Baohuside I; Icariin II; Icariside II. Grades: 98%. CAS No. 113558-15-9. Molecular formula: C27H30O10. Mole weight: 514.52. | |
| Iclaprim | Iclaprim is a diaminopyrimidine and acts as a dihydrofolate reductase (DHFR) inhibitor active against gram-positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. Alternative Names: AR-100; 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine; RO-48-2622. CAS No. 192314-93-5. Molecular formula: C19H22N4O3. Mole weight: 354.41. | |
| Icosanal | Icosanal. Alternative Names: Icosanal;Eicosanal;2400-66-0;FWBUWJHWAKTPHI-UHFFFAOYSA-N;EINECS219-275-5;AI3-24217. Grades: 95%. CAS No. 2400-66-0. Molecular formula: C20H40O. Mole weight: 296.53. | |
| Icosanamide | Icosanamide, a derivative of fatty acid, displays promise as a therapeutic agent for diverse inflammatory ailments. With its impressive anti-inflammatory attributes, the compound has garnered attention for handling autoimmune diseases and treating conditions such as rheumatoid arthritis. Its efficacy is well-documented in several clinical studies. Alternative Names: Eicosanamide; Arachamide. CAS No. 51360-63-5. Molecular formula: C20H41NO. Mole weight: 311.554. | |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Alternative Names: BPI-2009H. Grades: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42. | |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Alternative Names: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. Grades: >98%. CAS No. 677331-12-3. Molecular formula: C21H17N3O2S. Mole weight: 375.44. | |
| IDE-1 | IDE-1 was identified in a high throughput screen as an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells. IDE-1 is able to generate Sox17+/FoxA2+ cells to an equal or greater efficiency than that of protein (i.e. Activin A or Nodal) IDEs in mouse or human ES cell cultures. It functions in part via activation of TGF-β signaling, as evident by Smad2 phosphorylation. IDE-1 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos. Uses: Differentiation. Alternative Names: 7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid; IDE1; IDE-1; IDE 1. Grades: 0.98. CAS No. 1160927-48-9. Molecular formula: C15H18N2O5. Mole weight: 306.31. | |
| IFN alpha-IFNAR-IN-1 hydrochloride | IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptide, low-molecular-weight inhibitor. It inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3-L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM). Alternative Names: IFN alpha-IFNAR-IN-1 (hydrochloride); IFN-α-IFNAR-IN-1 (hydrochloride). Grades: 98%. CAS No. 2070014-98-9. Molecular formula: C18H18ClNS. Mole weight: 315.86. | |
| Ifosfamide | Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Alternative Names: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine; (±)-Ifosfamide; 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Holoxan 1000; Ifex; Ifomide; Ifosfamid; Ifosfomide; Ifosphamide; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Mitoxana; MJF 9325; Naxamide; NSC 109724; Z 4942. Grades: >98%. CAS No. 3778-73-2. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09. | |
| IKK 16 hydrochloride | IKK 16 hydrochloride is a potent and selective IκB kinase (IKK) inhibitor with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα, respectively. It inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Alternative Names: N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride; [4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone hydrochloride; Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-, hydrochloride (1:1). Grades: 98%. CAS No. 1186195-62-9. Molecular formula: C28H30ClN5OS. Mole weight: 520.09. | |
| ILK-IN-1 | ILK-IN-1, a ILK inhibitor, has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. IC50: 0.6 μM. Uses: Ilk-in-1 is a ilk inhibitor that has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. Alternative Names: ILK-IN-1; CHEMBL1830587; GTPL8116; SCHEMBL8536228; BDBM50353484; CS-4936; ILK inhibitor 22(1,5); T315(1,5); OSU-T315 (1,5-regioisomer); OSUT315; OSU T315; OSU-T315. Grades: 98%. CAS No. 1333146-24-9. Molecular formula: C30H30F3N5O. Mole weight: 533.59. | |
| Ilomastat | Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Alternative Names: GM6001; GM-6001; GM 6001; Ilomastat; galardin; (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanedia. Grades: 98%. CAS No. 142880-36-2. Molecular formula: C20H28N4O4. Mole weight: 388.468. | |
| Imatinib-[d4] | Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Alternative Names: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4; Imatinib D4. Grades: ≥98% (HPLC). CAS No. 1134803-16-9. Molecular formula: C29H27D4N7O. Mole weight: 497.64. | |
| Imatinib EP Impurity B | Imatinib EP Impurity B. CAS No. 581076-65-5. | |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Alternative Names: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1,4-bis[4-[(4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl)carbamoyl]benzyl]piperazin-1-ium chloride. Grades: > 95%. CAS No. 1821122-73-9. Molecular formula: C53H51ClN12O2. Mole weight: 923.50. | |
| Imatinib EP Impurity J | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Alternative Names: Imatinib (Piperidine)-N-oxide; 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 71422; CGP71422; CGP-71422. Grades: > 95%. CAS No. 571186-91-9. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib Impurity C | an impurity of Imatinib (Gleevec). Alternative Names: Imatinib (Piperidine)-1-oxide; 4-[(4-Methyl-1-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 938082-57-6. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib Impurity E | an impurity of Imatinib (Gleevec). Alternative Names: Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity; 4,4'-(piperazine-1,4-diylbis(methylene))bis(N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide). Grades: > 95%. CAS No. 1365802-18-1. Molecular formula: C52H48N12O2. Mole weight: 873.04. | |
| Imatinib Impurity M | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Alternative Names: 1,4-Bis(4-carboxybenzyl)-1-methylpiperazin-1-ium (Imatinib Impurity); 1,4-BIS(4-CARBOXYBENZYL)-1-METHYLPIPERAZIN-1-IUM; Imatinib Impurity M; SCHEMBL14646970; CS-0255288; F83280. CAS No. 1407229-73-5. Molecular formula: C21H25N2O4+. Mole weight: 369.44. | |
| (+/-)-Imazalil-[d5] Sulfate | (+/-)-Imazalil-[d5] Sulfate, is the labelled analogue of Imazalil. Imazalil, is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. Alternative Names: Imazalil-d5 Sulfate; 1-[2-(2,4-Dichlorophenyl)-2-[2-(propen-1-yl-d5)oxy]ethyl]-1H-imidazole Sulfate; 1-[2-(2,4-Dichlorophenyl)-2-[2-(propenyl-d5)oxy]ethyl]-1H-imidazole Sulfate; Chloramizol-d5 Sulfate; Microban Additive IF 4-d5; R 27180-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 1398065-92-3. Molecular formula: C14H11D5Cl2N2O5S. Mole weight: 400.28. | |
| IMD 0354 | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κβ pathway. Alternative Names: IMD-0354; IMD 0354; IMD0354. Grades: >98%. CAS No. 978-62-1. Molecular formula: C15H8ClF6NO2. Mole weight: 383.674. | |
| iMDK | iMDK is an inhibitor of midkine (MDK) expression, a growth factor commonly expressed in malignant tumors. iMDK dose-dependently inhibits MDK expression to attenuate certain tumor cell growth. It inhibits PI3K/Akt pathway thus induces apoptosis in MDK-expressing H441 lung adenocarcinoma cells. Uses: Antitumor agent. Alternative Names: 3-[2-(4-fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl]-2H-chromen-2-one. Grades: 98%. CAS No. 881970-80-5. Molecular formula: C21H13FN2O2S. Mole weight: 376.40. | |
| Imidapril HCl | Imidapril HCl is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. Grades: >98%. CAS No. 89396-94-1. Molecular formula: C20H27N3O6·HCl. Mole weight: 441.91. | |
| Imidocarb-[d8] dihydrochloride | Labelled Imidocarb 2HCl. Imidocarb 2HCl is a salt form of Imidocarb, which is a derivative of urea used as an antiprotozoal agent in the veterinary drug. Molecular formula: C19H14D8Cl2N6O. Mole weight: 429.37. | |
| Imiquimod-[d9] | Imiquimod-[d9] is a detuterated Imiquimod. Imiquimod is a medication of the immune response modifier class for the treatment of genital warts, superficial basal cell carcinoma, and actinic keratosis. Alternative Names: Imiquimod-d9; 1-(2-(methyl-d3)propyl-1,1,2,3,3,3-d6)-1H-imidazo[4,5-c]quinolin-4-amine; 4-amino-1-isobutyl-1h-imidazo[4,5-c]quinoline-d9. Grades: > 95%. CAS No. 2712126-48-0. Molecular formula: C14H7N4D9. Mole weight: 249.36. | |
| Imiquimod Related Compound B | A pharmacologically active compound related to Imiquimod, a toll-like receptor 7 agonist used as an immune response modifier. Alternative Names: Desamino Imiquimod N-Oxide; 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinoline 5-Oxide; 1-Isobutyl-1H-imidazo[4,5-c]quinoline N-Oxide; USP Imiquimod Related Compound B. Grades: > 95%. CAS No. 99010-63-6. Molecular formula: C14H15N3O. Mole weight: 241.30. | |
| Imisopasem manganese | Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo / radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. Alternative Names: M40403; M 40403; M 40403; CG4419; CG 4419; CG-4419; SC-72325; SC72325; SC 72325. Grades: >98%. CAS No. 218791-21-0. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.39. | |
| Imperialine | Imperialine is an isosteroidal alkaloid from Fritillaria thunbergii, a short-acting selective M2 muscarinic receptor antagonist. Alternative Names: Sipeimine; Raddeamine; (3-beta,5-alpha,17-beta)-3,20-dihydroxycevan-6-one; 3,20-dihydroxy-,(3-beta,5-alpha,17-beta)-cevan-6-on; kashmirine; (5α,17β)-3β,20-Dihydroxycevan-6-one. Grades: 97% (HPLC). CAS No. 61825-98-7. Molecular formula: C27H43NO3. Mole weight: 429.64. | |
| Imperialine-D-glucoside | Imperialine-D-glucoside is an alkaloid from Petilium eduardii (Liliaceae). Alternative Names: Edpetiline. Grades: >98%. CAS No. 32685-93-1. Molecular formula: C33H53NO8. Mole weight: 591.77582. | |
| IMR-1 | IMR-1 is a small-molecule inhibitor of Mastermind Recruitment-1. IMR-1 inhibits Notch target gene transcription via disrupting recruitment of Mastermind 1 to the Notch transcriptional activation complex on chromatin, thereby suppressing tumor growth. Alternative Names: IMR-1; IMR 1; IMR1. Inhibitor of Mastermind Recruitment-1; ethyl 2-[2-methoxy-4-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetate. Grades: >98%. CAS No. 310456-65-6. Molecular formula: C15H15NO5S2. Mole weight: 353.407. | |
Our database is helping our users find suppliers everyday.
