BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Leucoside | Leucoside is a flavonoid isolated from the herbs of Aesculus L. Alternative Names: Kaempferol 3-sambubioside; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 2-O-β-D-x ylopyranosyl-β-D-glucopyranoside. Grades: > 95%. CAS No. 27661-51-4. Molecular formula: C26H28O15. Mole weight: 580.5. |  |
| Levetiracetam EP Impurity B | Levetiracetam EP Impurity B is an impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Alternative Names: (2Z)-2-(2-oxopyrrolidin-1-yl)but-2-enamide. Grades: >95%. CAS No. 358629-47-7. Molecular formula: C8H12N2O2. Mole weight: 168.19. | |
| Levobetaxolol HCl | Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively. Alternative Names: AL 1577A; AL-1577A; AL1577A. Grades: >98%. CAS No. 116209-55-3. Molecular formula: C18H29NO3.HCl. Mole weight: 343.89. | |
| Levocarnitine EP Impurity D | An impurity of Levocarnitine. Alternative Names: (3-Carbamoylallyl)trimethylammonium; 4-Amino-N,N,N-trimethyl-4-oxobut-2-en-1-aminium. Grades: 95%. CAS No. 857162-57-3. Molecular formula: C7H15N2O. Mole weight: 143.21. | |
| Levofloxacin-007-S | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Grades: 95%. CAS No. 2130840-90-1. Molecular formula: C20H25FN4O4. Mole weight: 404.43. | |
| Levofloxacin Impurity 8-S | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Alternative Names: Levofloxacin-008-S. CAS No. 2130840-92-3. Molecular formula: C20H24FN3O4. Mole weight: 389.42. | |
| Levofloxacin Tetrafluoro Impurity 1 | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Alternative Names: (+)-ethyl 2-[[[(S)-1-hydroxyprop-2-yl]amino]methylene]-3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate. Grades: > 95%. CAS No. 110548-02-2. Molecular formula: C15H15F4NO4. Mole weight: 349.28. | |
| Levofloxacin USP Related Compound E | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Alternative Names: N,N'-Desethylene Levofloxacin Hydrochloride; Levofloxacin EP Impurity G. Grades: 95%. CAS No. 1346603-62-0. Molecular formula: C16H19ClFN3O4. Mole weight: 371.79. | |
| Levomilnacipran Hydrochloride | Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food and Drug Administration in July 2013. Levomilnacipran is the levo-enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin-norepinephrine reuptake inhibitor (SNRI). Uses: Antidepressive agents. Alternative Names: (1S,2R)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride; cis-(+)-Milnacipran Hydrochloride; (1S,2R)-Milnacipran Hydrochloride; (1S-cis)-Milnacipran Hydrochloride. Grades: 98%. CAS No. 175131-60-9. Molecular formula: C15H23ClN2O. Mole weight: 282.81. | |
| Levosimendan | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC). Uses: Vasodilator agents. Alternative Names: [[4-[(4R)-1,4,5,6-Terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile. Grades: >98%. CAS No. 141505-33-1. Molecular formula: C14H12N6O. Mole weight: 280.28. | |
| Levothyroxine EP Impurity F | An impurity of Thyroxine which is one of the two major hormones secreted by the thyroid gland and used to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Alternative Names: O-(4-Hydroxy-3,5-diiodophenyl)thyroxine; O-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-3,5-diiodo-L-tyrosine; T6. Grades: > 95%. CAS No. 911661-90-0. Molecular formula: C21H13I6NO5. Mole weight: 1120.77. | |
| Levothyroxine EP Impurity J | An impurity of Levothyroxine. Levothyroxine is used to treat hypothyroidism. Alternative Names: O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine; L-3,3'-Diiodothyronine; 3,3'-L-Diiodothyronine. Grades: >95%. CAS No. 4604-41-5. Molecular formula: C15H13I2NO4. Mole weight: 525.08. | |
| Levothyroxine N-methylamide | An impurity of Levothyroxine. Levothyroxine is used to treat hypothyroidism. Alternative Names: L-Thyroxine-N-methylamide; (S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide. Grades: 95%. CAS No. 2088032-52-2. Molecular formula: C16H14I4N2O3. Mole weight: 789.92. | |
| Levothyroxine sodium | Levothyroxine sodium is the hormone derived from thyroid gland. Alternative Names: L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1); Thyroxine, monosodium salt, L-; L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt; Dathroid; Eltroxin; Laevoxin; Levoroxine; Sodium levothyroxine; Sodium thyroxin; Sodium L-thyroxine; Sodium thyroxine; Thyroxine sodium; L-Thyroxine sodium; L-Thyroxine monosodium salt; L-Thyroxine sodium salt; Monosodium thyroxine; Sodium thyroxinate; Thyroxine sodium salt. CAS No. 55-03-8. Molecular formula: C15H10I4NNaO4. Mole weight: 798.856. | |
| LH846 | LH846 is a selective inhibitor of CK1δ, which displays no inhibitory activity at CK2. It inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein, showing to lengthen the circadian period in U2OS cells, with minimal effect on amplitude. Alternative Names: LH846; LH 846; LH-846. Grades: >98%. CAS No. 639052-78-1. Molecular formula: C16H13ClN2OS. Mole weight: 316.81. | |
| Liangshanin A | Liangshanin A is a natural diterpenoid found in the herbs of Rabdosia bulleyana. Alternative Names: Kaura-1,16-diene-3,15-dione, 7,14-dihydroxy-, (7a,14R)-. Grades: >98%. CAS No. 122717-54-8. Molecular formula: C20H26O4. Mole weight: 330.4. | |
| Licochalcone B | Licochalcone B is extracted from the roots of Glycyrrhiza glabra L. It inhibits the adhesion,invasion and metastasis of human malignant bladder cancer T24 cells. It could significantly reduce the LPS-induced production of NO, TNFalpha and MCP-1. Alternative Names: (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone; 3,4,4'-Trihydroxy-2-Methoxychalcone. Grades: >98%. CAS No. 58749-23-8. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Liensinine diperchlorate | Liensinine diperchlorate can be extracted from the plantule of Nelumbo nucifera Gaertn. Alternative Names: Liensinine diperchlorate; Liensinine (Diperchlorate); 5088-90-4; 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol; perchloric acid; HY-N0485; s9424; CCG-270503; MS-31504; CS-0009004. Grades: >98%. CAS No. 5088-90-4. Molecular formula: C37H42N2O6.(HClO4)2. Mole weight: 811.67. | |
| Liensinine perchlorate | Liensinine Perchlorate is extracted from the plantule of Nelumbo nucifera Gaertn. Alternative Names: 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]phenol perchlorate. Grades: >98%. CAS No. 2385-63-9. Molecular formula: C37H42N2O6.ClHO4. Mole weight: 711.2. | |
| Ligustrazine Hydrochloride | Ligustrazine Hydrochloride has certain protection effect on the vascular endothelium undergoing CPB, and lower excessive activation of coagulation reaction and inflammation reaction in patients undergoing CPB. Uses: Increased coronary flow. Alternative Names: LIGUSTRAZOINEHYDROCHLORIDE; 2,3,5,6-Tetramethylpyrazine hydrochloride; Chuanxiongzine Hydrochlorid; Chuanxiongzine Hydrochloride, TetraMethylpyrazine hydrochloride. Grades: >98%. CAS No. 76494-51-4. Molecular formula: C8H12N2.HCl. Mole weight: 208.69. | |
| Ligustroflavone | Ligustroflavone is isolated from Ligustrum vulgare, which shows anti-inflammatory and antioxidant activity. It has the potential as a calcium-sensing receptor (CaSR) antagonist. Uses: Anti-inflammatory. Alternative Names: ligustroflavone; 7-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1->2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1->6)]-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)- 4H-1-benzopyran-4-one; Nuezhenoside; Ligustroflavone(Nuezhenoside). Grades: >98%. CAS No. 260413-62-5. Molecular formula: C33H40O18. Mole weight: 724.67. | |
| Ligustroside | Ligustroside is isolated from the seeds of Ligustrum lucidum. Uses: Anti-inflammatory. Alternative Names: (2S)-3-[(E)-Ethylidene]-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4α-acetic acid 2-(4-hydroxyphenyl)ethyl ester. Grades: 98%. CAS No. 35897-92-8. Molecular formula: C25H32O12. Mole weight: 524.51. | |
| LIK066 | LIK066 is a potent sodium-glucose transporter 1 and sodium-glucose transporter 2 inhibitor originated by Novartis Pharmaceuticals Corporation IC50 with value of 22.0 nM against human SGLT1 and 0.5 nM against human SGLT2. In Apr 2016, Novartis completed a phase II trial for Type 2 diabetes mellitus in USA. Uses: Type 2 diabetes mellitus. Alternative Names: LIK-066; LIK 066; licogliflozin. Grades: 98%. CAS No. 1291094-73-9. Molecular formula: C51H65NO16. Mole weight: 948.07. | |
| Linagliptin-[d4] | Linagliptin-[d4] is a labelled form of Linagliptin, a medication used to treat diabetes mellitus type 2. Alternative Names: (R)-8-(3-Aminopiperidin-1-yl-2,2,6,6-d4)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione; 8-[(3S)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. CAS No. 2140263-92-7. Molecular formula: C25H24D4N8O2. Mole weight: 476.58. | |
| Linagliptin Impurity 7 Hydrochloride | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Alternative Names: (R)-N-(2-Acetylphenyl)-2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide hydrochloride. Molecular formula: C25H30ClN7O4. Mole weight: 528.00. | |
| Linagliptin Impurity B | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Alternative Names: 8-Bromo-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-; 8-Bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: ≥95%. CAS No. 2138392-83-1. Molecular formula: C26H21BrN8O2. Mole weight: 557.41. | |
| Linagliptin Impurity E | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Alternative Names: Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin; (R)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione. CAS No. 1446263-38-2. Molecular formula: C25H28N8O2. Mole weight: 472.5. | |
| Linagliptin S-isomer | Linagliptin S-isomer. CAS No. 668270-11-9. | |
| Linalool-[d5] | Linalool-[d5]. CAS No. 159592-39-9. Molecular formula: C10H13D5O. Mole weight: 159.28. | |
| Linaroside | Linaroside is a flavonoid glycoside isolated from some species of Linaria. Grades: 98.5%. CAS No. 53452-12-3. Molecular formula: C23H24O11. Mole weight: 476.44. | |
| Lincomycin-[13C,d3] | Lincomycin-[13C,d3] is the labelled analogue of Lincomycin. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. It inhibits bacterial protein synthesis. Alternative Names: Lincomycin-13C,D3; (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-13C,D3-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Lincocin-13C,D3; Lincogap-13C,D3; NSC 70731-13C,D3. Molecular formula: C17[13C]H31D3N2O6S. Mole weight: 410.55. | |
| Linderaspirone A | Linderaspirone A, that is extracted from the roots of Lindera aggregata( Sims) Kosterm, showed significant activity against glucosamine-induced insulin resistance. Alternative Names: (8R,16R)-rel-2,3,6,11,12,14-Hexamethoxy-8,16-diphenyldispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone. Grades: >98%. CAS No. 1235126-46-1. Molecular formula: C34H32O10. Mole weight: 600.6. | |
| Linezolid-[d3] | Linezolid-[d3] is the labelled analogue of Linezolid, which is an antibiotic used to treat infections caused by Gram-positive bacteria. Alternative Names: Linezolid D3; N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide-d3; Linospan-d3; Linox-d3; Zyvox-d3; Zyvoxid-d3. Grades: ≥98%; ≥99% atom D. CAS No. 1127120-38-0. Molecular formula: C16H17D3FN3O4. Mole weight: 340.36. | |
| Linezolid Impurity 42 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Alternative Names: 2-amino-3-chloropropan-1-ol; Linezolid Impurity 42; 725676-93-7; AKOS006352833. Grades: 95%. CAS No. 725676-93-7. Molecular formula: C3H8ClNO. Mole weight: 109.55. | |
| Linezolid Impurity 44 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Alternative Names: N-[(2S)oxiranylmethyl]acetamide; Acetamide, N-[(2S)-oxiranylmethyl]-; N-[[(2S)-oxiran-2-yl]methyl]acetamide; (S)-(+)-N-(oxiranylMethyl)acetaMide; (S)-N-oxiranylmethyl-acetamide; SCHEMBL2863034; (s)-n-(oxiranylmethyl)acetamide; DTXSID80453297; HBTVZPMDLRPWKZ-YFKPBYRVSA-N; N-[(2S)oxiranylmethyl] acetamide; (S)-N-(Oxiran-2-ylmethyl)acetamide; CS-0166034; (S)-N-(oxiran-2-ylmethyl)acetamide? (Brexpiprazole Impurity pound(c). Grades: 95%. CAS No. 183805-10-9. Molecular formula: C5H9NO2. Mole weight: 115.13. | |
| Linezolid N-Oxide | Linezolid N-oxide is a derivative of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Alternative Names: (S)-4-{4-[5-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl}morpholine 4-oxide; N-[[(5S)-3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-[[3-[3-Fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Acetamide, N-[[3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-; N-[[(5S)-3-[3-Fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide. Grades: ≥95%. CAS No. 189038-36-6. Molecular formula: C16H20FN3O5. Mole weight: 353.35. | |
| Linifanib | Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine / threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3). Alternative Names: ABT869; ABT 869; ABT-869; Linifanib. CAS No. 796967-16-3. Molecular formula: C21H18FN5O. Mole weight: 375.407. | |
| Lipid 5 | Lipid 5 is a cationic amino lipid. LNPs incorporating Lipid 5 (from Sabnis et al.) demonstrated potent delivery of mRNA in primates but also were rapidly cleared from the body resulting in low toxicity. Alternative Names: Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)-8-oxooctyl)amino)octanoate. Grades: 95% by NMR / HPLC-ELSD. CAS No. 2089251-33-0. Molecular formula: C44H87NO5. Mole weight: 710.18. | |
| Liquiritin apioside | Liquiritin apioside is found in Glycyrrhiza uralensis and Glycyrrhiza glabra. Alternative Names: Liquiritin apioside; 74639-14-8; UNII-8T57TH2CCD; 8T57TH2CCD; Liquiritigenin 4'-o-apiosyl-O-glucoside; Liquiritigenin-4'-o-apiosyl(1->2)glucoside; DTXSID20904894; 4H-1-Benzopyran-4-one, 2-(4-((2-o-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy)phenyl)-2,3-dihydro-7-hydroxy-, (2S)-; (2S)-2-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-hydroxy-2,3-dihydrochromen-4-one; (S)-2-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-7-hydroxychroman-4-one; CHEMBL4205314; CHEBI:191629; DTXCID301334003; LIQUIRITIN APIOSIDE [INCI]; HY-N1471; MFCD09260034; AKOS037514724; AC-34257; AS-35047; CS-0016965; A865847; Q27270984; 4H-1-BENZOPYRAN-4-ONE, 2-(4-((2-O-D-APIO-.BETA.-D-FURANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)PHENYL)-2,3-DIHYDRO-7-HYDROXY-, (2S)-. Grades: >98%. CAS No. 74639-14-8. Molecular formula: C26H30O13. Mole weight: 550.5. | |
| Liraglutide-[d4] | Liraglutide-[d4] is the labelled analogue of Liraglutide. Liraglutide activates AMP-activated protein kinase thus enhancing insulin sensitivity, is the long-acting analogue of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Alternative Names: L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-glycine-d4; Liraglutide D4. Molecular formula: C172H261D4N43O51. Mole weight: 3755.23. | |
| Lisaftoclax | Lisaftoclax is a dual Bcl-2 and Bcl-xl inhibitor with antineoplastic activity. Alternative Names: Bcl-2/Bcl-xl inhibitor 1; APG-2575; (S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3-nitrophenyl)sulfonyl)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4-chlorophenyl)spiro[3.5]non-6-en-7-yl)methyl)piperazin-1-yl)benzamide. Grades: 98%. CAS No. 2180923-05-9. Molecular formula: C45H48ClN7O8S. Mole weight: 882.42. | |
| Lisinopril Impurity D | An impurity of ACE inhibitor Lisinopril, which is indicated for the treatment of high blood pressure and heart failure. Alternative Names: Lisinopril (S,S,R)-Diketopiperazine; (2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-phenylbutanoic acid. Grades: > 95%. CAS No. 219677-82-4. Molecular formula: C21H29N3O4. Mole weight: 387.47. | |
| (+/-)-Lisofylline-[d6] | (+/-)-Lisofylline-[d6] is the labelled analogue of (+/-)-Lisofylline, which is a major oxidative metabolite of Pentoxifylline. Pentoxifylline is a potent inhibitor of phosphatidic acid generation. Alternative Names: Lisofylline-D6; (+/-)-Lisofylline-d6; 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-(dimethyl-d6)-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl)theobromine-d6; (+/-)-1-(5-Hydroxyhexyl)-3,7-(dimethyl-d6)xanthine; Pentoxifylline-d6 Alcohol; Hydroxypentoxifylline-d6. Grades: ≥98% by HPLC; ≥99% atom D. CAS No. 1185995-26-9. Molecular formula: C13H14D6N4O3. Mole weight: 286.37. | |
| Litseglutine B | Litseglutine B, also called 2-Hydroxy-1,10,11-trimethoxyaporphine, is a natural alkaloid found in the herbs of Litsea glutinosa. Alternative Names: 2-Hydroxy-1,10,11-trimethoxyaporphine. Grades: >95%. CAS No. 25368-01-8. Molecular formula: C20H23NO4. Mole weight: 341.4. | |
| LKB1/AAK1 dual inhibitor | LKB1/AAK1 dual inhibitor is an effective inhibitor against multi-kinase especially Pim-1 kinase, which has been newly found to be highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1. Alternative Names: LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275; Pim1/AKK1-IN-1; N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide; Pim1 AKK1-IN-1. Grades: 98%. CAS No. 1093222-27-5. Molecular formula: C20H13N5O. Mole weight: 339.35. | |
| L-Kynurenine-[13C4,15N] | L-Kynurenine-[13C4,15N] is a labelled L-kynurenine. L-Kynurenine Sulfate is a tryptophan metabolite which is a precursor of kynurenic acid and an antagonist of N-methyl-aspartate receptor. Alternative Names: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid-13C4,15N; L-Kynurenine-13C4,15N. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. Molecular formula: C6[13C]4H12N[15N]O3. Mole weight: 213.17. | |
| LM 10 | LM 10 is a selective TDO inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Alternative Names: LM10; LM 10; LM-10. 6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole. Grades: > 98%. CAS No. 1316695-35-8. Molecular formula: C11H8FN5. Mole weight: 229.21. | |
| Lobaplatin | Lobaplatin is a diastereometric mixture of platinum(II) complexes identified as a new platinum drug. Its antitumour activity results from the formation of DNA-drug adducts, mainly as GG and AG intra-strand cross-links. Alternative Names: D-19466; D 19466; D19466. Grades: >98%. CAS No. 135558-11-1. Molecular formula: C9H18N2O3Pt. Mole weight: 397.328. | |
| Lobeline EP Impurity A HCl | An impurity of Lobeline, a pyridine alkaloid found in a variety of plants, particularly those in the genus Lobelia. Alternative Names: Lobeline EP Impurity A. Grades: > 95%. CAS No. 731823-86-2. Molecular formula: C22H28ClNO2. Mole weight: 373.92. | |
| Lobenzarit disodium | Lobenzarit disodium is an immunomodulator commonly used for the treatment of arthritis. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: Lobenzarit sodium; Lobenzarit disodium salt; Disodium 4-chloro-2,2'-iminobenzoate; disodium 2-(2-carboxylatoanilino)-4-chlorobenzoate. Grades: >98%. CAS No. 64808-48-6. Molecular formula: C14H8ClNNa2O4. Mole weight: 335.651. | |
| LOCHNERINE | Lochnerine is a natural alkaloid found in the herbs of Catharanthus roseus (L.) G. Don. Alternative Names: 10-Methoxysarpagan-17-ol; 10-Methoxynormacusine B; 10-O-Methylsarpagine. Grades: >98%. CAS No. 522-47-4. Molecular formula: C20H24N2O2. Mole weight: 324.4. | |
| Lodoxamide tromethamine | Lodoxamide is a GPR35 agonist that has been used as a mast cell stabilizer. It can be used for topical administration into eyes indicated for allergic symptom treatment. Alternative Names: Alomide; Lodoxamidetromethamine. CAS No. 63610-09-3. Molecular formula: C19H28ClN5O12. Mole weight: 553.9. | |
| Loflucarban | Loflucarban is an antifungal agent. Alternative Names: Loflucarban; NSC 76851; NSC-76851; NSC76851; Fluonilid; Fluonilide; 3,5-Dichloro-4'-fluorothiocarbanilide; 1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea. CAS No. 790-69-2. Molecular formula: C13H9Cl2FN2S. Mole weight: 315.187. | |
| Loliolide | Loliolide is a germination inhibitor that is isolated from Sargassum ringgoldianum subsp. coreanum. Loliolide exhibits antioxidant activity to protect the cells against H2O2-induced cell damage or apoptosis. Alternative Names: (3S,5R)-Loliolide. Grades: 98.0%. CAS No. 5989-2-6. Molecular formula: C11H16O3. Mole weight: 196.246. | |
| Lomefloxacin-[d5] | Lomefloxacin-[d5] is the labelled salt of Lomefloxacin, which is a fluorinated quinolone antibacterial agent and a DNA gyrase antagonist. Alternative Names: Lomefloxacin-D5 ; 1-Ethyl-d5-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid; Alkaflox-d5; Bareon-d5; Chimono-d5; Lomebact-d5; Lomflox-d5; Lomitas-d5; Lomoxin-d5; Maxaquin-d5; Mazaquin-d5; Orchacin-d5; Uniquin-d5. Molecular formula: C17H14D5F2N3O3. Mole weight: 356.38. | |
| Lomefloxacin-[d5] hydrochloride | Lomefloxacin-[d5] hydrochloride is the labelled salt of Lomefloxacin, which is a fluorinated quinolone antibacterial agent and a DNA gyrase antagonist. Alternative Names: Lomefloxacin-D5 hydrochloride; 1-Ethyl-d5-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox-d5; Bareon-d5; Chimono-d5; Lomebact-d5; Lomflox-d5; Lomitas-d5; Lomoxin-d5; Maxaquin-d5; Mazaquin-d5; Orchacin-d5; Uniquin-d5. Grades: 95% by HPLC; 98% atom D. Molecular formula: C17H14D5F2N3O3.HCl. Mole weight: 392.84. | |
| Lomitapide | Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Uses: The treatment of familial hypercholesterolemia. Alternative Names: Juxtapid; Lojuxta; AEGR 733; AEGR-733; AEGR733; BMS-201038. Grades: > 98%. CAS No. 182431-12-5. Molecular formula: C39H37F6N3O2. Mole weight: 693.734. | |
| Longikaurin E | Longikaurin E is isolated from the herbs of Rabdosia nervosa. It could be a promising anti-pancreatic agent. Uses: Antibacterial. Alternative Names: 11α-Acetoxy-7α,20-epoxy-6β,7-dihydroxykaur-16-en-15-one; (4aR,5S,6R,6aS,9S,11R,11aS,11bS)-5,6-dihydroxy-4,4-dimethyl-8-methylene-7-oxododecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-11-yl acetate. Grades: 98%. CAS No. 77949-42-9. Molecular formula: C22H30O6. Mole weight: 390.5. | |
| Longistylumphylline A | Longistylumphylline A is isolated from the herbs of Daphniphyllum macropodum. Alternative Names: Longistylumphylline A;1H-11,12c-Methanocyclopent[1,8]azuleno[4,5-a]indolizine-2-carboxylic acid, 3,4,5,6,6a,7,9,10,11,12,12a,12b-dodecahydro-10,12b-dimethyl-13-oxo-, methyl ester, (6aR,10R,11S,12aS,12bR,12cS)-rel-(-)-. Grades: 96.5%. CAS No. 857672-34-5. Molecular formula: C23H29NO3. Mole weight: 367.5. | |
| Loperamide-[d6] Hydrochloride | Loperamide-[d6] Hydrochloride is the labelled Loperamide, which is used as an antidiarrheal. Alternative Names: 4-(4-Chlorophenyl)-4-hydroxy-N,N-(dimethyl-d6)-α,α-diphenyl-1-piperidinebutanamide Hydrochloride; Arret-d6; Blox-d6; Brek-d6; Dissenten-d6; Fortasec-d6; Imodium-d6; Imodium A-D-d6; Imosec-d6; Imossel-d6; Lopemid-d6; Lopemin-d6; Loperazine-d6; Loperyl-d6. Grades: > 95%. CAS No. 1189469-46-2. Molecular formula: C29H28D6Cl2N2O2. Mole weight: 519.54. | |
| Lophanthoidin E | Lophanthoidin E, also called (6β,7α)-6,7,12-Trihydroxy-11,14-dioxoabieta-8,12-dien-16-yl aceta te, is a natural diterpenoid found in the herbs of Rabdosia lophanthoides. Alternative Names: (6β,7α)-6,7,12-Trihydroxy-11,14-dioxoabieta-8,12-dien-16-yl aceta te. Grades: >95%. CAS No. 120462-45-5. Molecular formula: C22H30O7. Mole weight: 406.5. | |
| Lophanthoidin F | Lophanthoidin F is a natural diterpenoid found in the herbs of Rabdosia lophanthoides. Alternative Names: (6β,7α)-7-Ethoxy-6,12-dihydroxy-11,14-dioxoabieta-8,12-dien-16-yl acetate. Grades: >95%. CAS No. 120462-46-6. Molecular formula: C24H34O7. Mole weight: 434.5. | |
| Lornoxicam | Lornoxicam is a non-steroidal COX-1/COX-2 inhibitor used as an anti-inflammatory drug. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: Chlortenoxicam; Xefocam; Xefo. Grades: > 95%. CAS No. 70374-39-9. Molecular formula: C13H10ClN3O4S2. Mole weight: 371.82. | |
| Losartan Carboxaldehyde | Losartan Carboxaldehyde is a metabolite of Losartan. It is an intermediate in the synthesis of the EXP 3174. Alternative Names: Losartan Potassium Impurity K; 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-carbaldehyde; 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde; EXP 3179; DUP 167; Losartan Potassium EP Impurity K; Losartan Impurity K. Grades: >95%. CAS No. 114798-36-6. Molecular formula: C22H21ClN6O. Mole weight: 420.89. | |
| Losartan Potassium EP Impurity E | An impurity of Losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Alternative Names: Losartan Potassium Impurity E; Losartan Impurity E; 5-(4'-Methyl-2-biphenyl)tetrazole; 5-(4'-Methyl[1,1'-biphenyl]-2-yl)-2H-tetrazole; 2-(Tetrazol-5-yl)-4'-methyl-1,1'-biphenyl; 5-[2-(4'-Methylbiphenyl)]tetrazole; L 158507; 5-(4'-Methyl-1,1'-biphenyl-2-yl)-1H-tetrazole; 5-(4'-Methylbiphenyl-2-yl)-1H-tetrazole; 5-(4'-Methylbiphenyl-2-yl)tetrazole. Grades: ≥95%. CAS No. 120568-11-8. Molecular formula: C14H12N4. Mole weight: 236.27. | |
| Loureirin A | Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Alternative Names: 3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone. Grades: 98.5%. CAS No. 119425-89-7. Molecular formula: C17H18O4. Mole weight: 286.32. | |
| Loureirin D | Loureirin D is a chalcone isolated from Dracaena cochinchinensis. Grades: 98%. CAS No. 119425-91-1. Molecular formula: C16H16O5. Mole weight: 288.29. | |
| Lovastatin-[d3] | Lovastatin-[d3] is the labelled analogue of Lovastatin, which is a fungal metabolite and an inhibitor of HMG-CoA reductase. Lovastatin is an antihypercholesterolemic agent. Alternative Names: (2S)-2-(Methyl-d3)butanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro- 3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; MK-803-d3; Lovalip-d3; Lovastatin Lactone-d3; Mevacor-d3; Mevinacor-d3. Grades: 98%; ≥99% atom D. CAS No. 1002345-93-8. Molecular formula: C24H33D3O5. Mole weight: 407.56. | |
| Lovastatin EP Impurity B (Sodium salt) | Lovastatin EP Impurity B (Sodium salt) is a metabolite of Lovastatin which is an antihypercholesterolemic agent. Alternative Names: Lovastatin Sodium; Sodium mevinolinate; Lovastatin sodium salt; Lovastatin Hydroxy Acid, Sodium Salt; Lovastatin hydroxy acid sodium salt; Mevinolin sodium. Grades: 95%. CAS No. 75225-50-2. Molecular formula: C24H37NaO6. Mole weight: 444.54. | |
| Loxiglumide | Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Uses: Loxiglumide stimulates calorie intake and hunger feelings in humans. it inhibits pancreatic secretion of digestive enzymes. Alternative Names: CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid. Grades: 95%. CAS No. 107097-80-3. Molecular formula: C21H30Cl2N2O5. Mole weight: 461.38. | |
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