BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Methyl 4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoate | Methyl 4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoate is a remarkably versatile chemical compound whose functionality within the biomedical industry can scarcely be overstated. Serving as a vital intermediate in the synthesis of a multitude of drugs - including those directed at diseases as menacing as cancer, autoimmune disorders, and inflammation - it represents a key facet of the search for effective therapeutic modalities. Such a role cannot be understated, as the discovery and implementation of effective pharmacological agents critically relies on the availability of reliable and potent compounds like Methyl 4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoate. Alternative Names: Methyl 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]benzoate; 4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl)carbamoyl]benzoic acid methyl ester; N-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-terephthalamic acid methyl ester; Benzoic acid, 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]-, methyl ester. Grades: 95%. CAS No. 94497-53-7. Molecular formula: C23H27NO3. Mole weight: 365.47. |  |
| Methyl [6,6]-phenyl-C61-butyrate | Methyl [6,6]-phenyl-C61-butyrate. CAS No. 160848-22-6. | |
| Methyl 7α,15-dihydroxydehydroabietate | Methyl 7α,15-dihydroxydehydroabietate is extracted from the barks of Pinus yunnanensis. Alternative Names: Methyl 7,15-dihydroxydehydroabietate; methyl (1R,4aS,9R,10aR)-9-hydroxy-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate. Grades: 95.0%. CAS No. 155205-65-5. Molecular formula: C21H30O4. Mole weight: 346.47. | |
| methyl 7-oxoheptanoate | methyl 7-oxoheptanoate. Alternative Names: Heptanoic acid, 7-oxo-,methyl ester; 7-oxoheptanoic acid methyl ester; 7-oxo-heptanoic acid methyl ester. Grades: 95%. CAS No. 35376-00-2. Molecular formula: C8H14O3. Mole weight: 158.19. | |
| Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate | Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate is purified from the roots of Polygala fallax. Grades: 96.0%. CAS No. 96287-41-1. Molecular formula: C17H14O8. Mole weight: 346.29. | |
| Methyl Benzo[b]thiophene-2-carboxylate | Methyl Benzo[b]thiophene-2-carboxylate. Alternative Names: N-(4-nitrophenyl)-3-oxobutanamide;N-(4-Nitrophenyl)-3-oxobutanamide;4835-39-6;4'-Nitroacetoacetanilide;n-(4-nitro-phenyl)-3-oxo-butyramide;N-(4-NITROPHENYL)-3-OXOBUTYRAMIDE. Grades: 95%. CAS No. 229132-24-2. Molecular formula: C10H10N2O4. Mole weight: 222.1974. | |
| Methyl β-carboline-1-carboxylate | 1-Methoxycarbonyl-β-carboline is isolated from the barks of Picrasma quassioides. Alternative Names: Methyl β-carboline-1-carboxylate; 9H-Pyrido[3,4-b]indole-1-carboxylic acid methyl ester. Grades: > 95%. CAS No. 3464-66-2. Molecular formula: C13H10N2O2. Mole weight: 226.2. | |
| Methyl clerodermate | Methyl clerodermate is a natural diterpenoid isolated from the herbs of Clerodendrum inerme. Alternative Names: Clerodermic acid methyl ester. Grades: >98%. CAS No. 67650-47-9. Molecular formula: C21H30O4. Mole weight: 346.5. | |
| Methyl demethoxycarbonylchafruticosinate | Methyl demethoxycarbonylchanofruticosinate is isolated from the herbs of Kopsia hainanensis. It exhibits significant antitussive activity in a guinea pig cough model induced by citric acid. Uses: Antitussive activity. Alternative Names: Des-N-(methoxycarbonyl)chanofruticosinic acid methyl ester. Grades: 95%. CAS No. 80151-89-9. Molecular formula: C21H24N2O3. Mole weight: 352.4. | |
| Methyl isodrimeninol | Methyl isodrimeninol is isolated from the herbs of Polygonum flaccidum Meissn. Grades: 95%. CAS No. 442851-27-6. Molecular formula: C16H26O2. Mole weight: 250.38. | |
| Methylisoindigotin | Meisoindigo is a derivative of indirubin with antitumor activity, which has been used in China for chronic myeloid leukemia. Meisoindigo is an apoptosis inducer and potential agent for the treatment of AML. It inhibits the growth of leukemic cells by inducing marked apoptosis and moderate cell-cycle arrest at the G(0)/G(1) phase. Alternative Names: Methylisoindigotin; N-Methylisoindigotin; (3E)-1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one. Grades: >98%. CAS No. 97207-47-1. Molecular formula: C17H12N2O2. Mole weight: 276.29. | |
| (-)-Methyl Jasmonate-[d3] | (-)-Methyl Jasmonate-[d3]. Uses: Labelled jasmonic acid. a major constituent of essential oil of jasmine. used by the fragrance industry. this product is a clear, colorless to very light yellow oil that adheres to the surface of the vial. Alternative Names: Cyclopentaneacetic acid, 3-oxo-2-[(2Z)-2-penten-1-yl-5,5,5-d3]-, methyl ester, (1R,2R)-rel-; (-)-Jasmonic Acid Methyl Ester-d3; (-)-Methyl Jasmonate-d3; (1R,2R)-Jasmonic Acid Methyl Ester-d3; (Z)-Methyl Jasmonate-d3. Grades: ≥95%. CAS No. 903510-51-0. Molecular formula: C13H17D3O3. Mole weight: 227.31. | |
| Methylophiopogonanone B | Methylophiopogonanone B is a flavonoid isolated from the roots of Ophiopogon japonicus. Alternative Names: 8-Methylophiopogonanone B; (3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one. Grades: >=98%. CAS No. 74805-91-7. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Methylprednisolone Acetate EP Impurity D | Methylprednisolone Acetate EP Impurity D is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Molecular formula: C44H58O9. Mole weight: 730.92. | |
| Methyl pseudolarate B | Methyl pseudolarate B is isolated from the root bark of Pseudolarix kaempferi. Alternative Names: Methyl (1R,7S,8S,9R)-7-acetoxy-9-[(1E,3E)-5-methoxy-4-methyl-5-oxo-1,3-pentadien-1-yl]-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylate. Grades: 98%. CAS No. 82508-34-7. Molecular formula: C24H30O8. Mole weight: 446.5. | |
| Methyl rosmarinate | Methyl rosmarinate is isolated from the herb of Rosmarinus officinalis L. It is a noncompetitive tyrosinase inhibitor with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase. Uses: Antifungal activity. Alternative Names: Methylrosmarinic acid; (+)-Methyl rosmarinate; (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (E)-3-(3,4-dihydroxyphenyl)acrylate. Grades: 95%. CAS No. 99353-00-1. Molecular formula: C19H18O8. Mole weight: 374.34. | |
| (Methyl)tri-4-tolylphosphonium Iodide-[d3,13C] | (Methyl)tri-4-tolylphosphonium Iodide-[d3,13C]. Alternative Names: (Methyl)tris(4-methylphenyl)phosphonium Iodide-d3,13C; (Methyl)tris(p-tolyl)phosphonium Iodide-d3,13C. CAS No. 1896-61-3. Molecular formula: C21[13C]H21D3IP. Mole weight: 450.32. | |
| Methyltricaprylylammonium triflate | Methyltricaprylylammonium triflate. CAS No. 121107-18-4. | |
| (Methyl)triphenylphosphonium Iodide-[d3,13C] | (Methyl)triphenylphosphonium Iodide-[d3,13C]. Uses: Wittig reagent. Alternative Names: (Methyl)triphenyl-phosphonium Iodide-d3,13C; Triphenyl(trideuteriomethyl)phosphonium Iodide-13C. CAS No. 282107-30-6. Molecular formula: C18[13C]H15D3PI. Mole weight: 408.24. | |
| Metoclopramide hydrochloride hydrate | Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist used to treat nausea and vomitin. Uses: A dopamine d2 antagonist. Alternative Names: Maxolon; AHR-3070-C; Maxolon; Metoclopramide HCl; Metoclopramide hydrochloride; Metoclopramide monohydrochloride monohydrate; Metozolv; Reglah. Grades: ≥98%. CAS No. 54143-57-6. Molecular formula: C14H25Cl2N3O3. Mole weight: 354.3. | |
| Metolachlor | Metolachlor is a selective pre-emergence herbicide. It is used for grass and broadleaf weed control in corn, soybean, peanuts, sorghum, and cotton. Alternative Names: Pennant; 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide. Grades: >95%. CAS No. 51218-45-2. Molecular formula: C15H22ClNO2. Mole weight: 283.79. | |
| Metolcarb-[d3] | Metolcarb-[d3] is a deuterium labelled Metolcarb, a carbamate ester used as an acaricide and insecticide. Alternative Names: Metolcarb-d3. CAS No. 1777782-68-9. Molecular formula: C9H8D3NO2. Mole weight: 168.21. | |
| Metoprolol EP Impurity H | Metoprolol EP Impurity H. CAS No. 62572-94-5. | |
| Metoprolol Impurity A | C-Desmethyl Metoprolol is a new byproduct detected in Metoprolol tartrate. It is a Metoprolol impurity. Alternative Names: C-Desmethyl Metoprolol; 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol; H 173/09; USP Metoprolol Related Compound A. Grades: > 95%. CAS No. 109632-08-8. Molecular formula: C14H23NO3. Mole weight: 253.34. | |
| Metoprolol Impurity D | 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol is a new byproduct detected in Metoprolol tartrate. It is a Metoprolol impurity. Alternative Names: 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol; H 93/82. Grades: > 95%. CAS No. 62572-90-1. Molecular formula: C12H18O4. Mole weight: 226.27. | |
| Metoxuron-[d6] | Metoxuron-[d6]. Alternative Names: Metoxuron D6. Grades: >95%. CAS No. 2030182-41-1. Molecular formula: C10H7D6ClN2O2. Mole weight: 234.71. | |
| Metoxuron-monomethyl-[d3] | Metoxuron-monomethyl-[d3]. Molecular formula: C9H8D3ClN2O2. Mole weight: 217.67. | |
| Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc | Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: β-D-Glucopyranosiduronic acid, 2-[[3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]amino]-4-(hydroxymethyl)phenyl, methyl ester, 2,3,4-triacetate; (2S,3S,4S,5R,6S)-methyl-6-(2-(3-(((9H-fluoren-9-yl)methoxy)carbonyl-amino) propanamido)-4-(hydroxymethyl)phenoxy)-3,4,5-triacetoxy-tetrahydro-2H-pyran-2-carboxylate. Grades: >98.0%. CAS No. 894096-02-7. Molecular formula: C38H40N2O14. Mole weight: 748.73. | |
| Metribuzin | Metribuzin is a herbicide that is used both pre- and post-emergence in crops. It functions via inhibiting photosynthesis by disrupting photosystem II. Alternative Names: Lexone; Sencor; Metribuzine; 3-Methylthio-4-amino-6-tert-butyl-1,2,4-triazin-5(4H)-one; 4-Amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one. Grades: >95%. CAS No. 21087-64-9. Molecular formula: C8H14N4OS. Mole weight: 214.29. | |
| Metronidazole Impurity D | An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Alternative Names: 2-(5-Nitro-1H-imidazol-1-yl)ethanol; 5-Nitro-1H-imidazole-1-ethanol; 1H-Imidazole-1-ethanol, 5-nitro-. Grades: > 95%. CAS No. 5006-68-8. Molecular formula: C5H7N3O3. Mole weight: 157.13. | |
| Metronidazole Impurity E | An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Alternative Names: 2-Methyl-4-nitro-1H-imidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole. Grades: > 95%. CAS No. 705-19-1. Molecular formula: C6H9N3O3. Mole weight: 171.16. | |
| Metronidazole Impurity F | An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Alternative Names: 2-[2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethoxy]ethanol; Metronidazole Impurity F; 2-[2-(2-Methyl-5-nitroimidazol-1-yl)ethoxy]ethanol;O-Hydroxyethyl Metronidazole. Grades: > 95%. CAS No. 16156-94-8. Molecular formula: C8H13N3O4. Mole weight: 215.21. | |
| Metronidazole Impurity G | An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Alternative Names: 2-Methyl-5-nitroimidazol-1-ylacetic Acid; 1-De(2-hydroxyethyl)metronidazole-1-acetic Acid; 2-Methyl-5-nitro-1H-imidazole-1-acetic Acid; 2-Methyl-5-nitro-Imidazole-1-acetic Acid; Metronidazoleacetic Acid. Grades: > 95%. CAS No. 1010-93-1. Molecular formula: C6H7N3O4. Mole weight: 185.14. | |
| (+/-)-Mevalonolactone-[4,4,5,5-d4] | (+/-)-Mevalonolactone-[4,4,5,5-d4] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Alternative Names: Mevalonolactone-4,4,5,5 D4. Grades: 97% by CP; 98% atom D. CAS No. 349553-98-6. Molecular formula: C6H6D4O3. Mole weight: 134.17. | |
| MGB Eclipse® CPG | MGB Eclipse® CPG. | |
| MGH-CP1 | MGH-CP1 is a potent and selective inhibitor of transcriptional enhanced associate domain (TEAD) palmitoylation. It exhibits dose-dependent and potent inhibition of TEAD2/4 auto-palmitoylation in vitro with IC50 of 710 nM and 672 nM, respectively. Alternative Names: 2-((1H-1,2,4-Triazol-5-yl)thio)-N-(4-(adamantan-1-yl)phenyl)acetamide. CAS No. 896657-58-2. Molecular formula: C20H24N4OS. Mole weight: 368.50. | |
| MI-463 | MI-463, a thienopyrimidine derivative, has been found to be a menin inhibitor that could be significant in Leukaemia studies. Alternative Names: MI-463; MI 463; MI463; 4-methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile. Grades: 98%. CAS No. 1628317-18-9. Molecular formula: C24H23F3N6S. Mole weight: 484.55. | |
| (±)-Mianserin-[d3] Hydrochloride | (±)-Mianserin-[d3] Hydrochloride is the labelled salt of (±)-Mianserin, which is a serotonin receptor antagonist and could be used as an antidepressant agent. Alternative Names: Mianserin-d3 HCl; (±)-Mianserin-d3 Hydrochloride (methyl-d3); 1,2,3,4,10,14b-Hexahydro-2-(methyl-d3)-dibenzo[c,f]pyrazino[1,2-a]azepine Hydrochloride. Grades: 95% by HPLC; 98% atom D. CAS No. 1219804-97-3. Molecular formula: C18H18D3ClN2. Mole weight: 303.85. | |
| Micafungin Epimer Impurity | Micafungin Epimer Impurity is an impurity of Micafungin, an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Alternative Names: Sodium 5-((1S,2S)-2-((2R,6S,9S,11R,12S,14aS,15S,16S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl Sulfate. Grades: 95%. CAS No. 1392514-05-4. Molecular formula: C56H70N9NaO23S. Mole weight: 1292.26. | |
| Micafungin Impurity 3 | Micafungin Impurity 3 is an impurity of Micafungin, it is used to optimize the side chain of the natural product FR901379. Alternative Names: 4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid; Benzoic acid, 4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]-; 4-[5-(4-pentyloxyphenyl)isoxazol-3-yl]benzoic acid; 4-[5-(4-pentoxyphenyl)-1,2-oxazol-3-yl]benzoic Acid; 4-{5-[4-(Pentyloxy)phenyl]isoxazol-3-yl}benzoic acid; SCHEMBL2353533; PDTXSIGPZDVVIX-UHFFFAOYSA-N; MFCD20267356; AKOS025395935; DS-8489; SB18167; AM20090710; CS-0160970; F52834; A924886; A1-01692; 4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoicacid; 4-[5-(4-n-pentyloxyphenyl)isoxazol-3-yl]benzoic acid; 4-(5-{4-[(Pent-1-yl)oxy]phenyl}isoxazol-3-yl)benzoic acid; 4-{5-[4-(PENTYLOXY)PHENYL]-1,2-OXAZOL-3-YL}BENZOIC ACID; 4-{5-[4-(Pentyloxy)phenyl]-1,2-oxazol-3-yl}benzoic acid, 3-(4-Carboxyphenyl)-5-[4-(pentyloxy)phenyl]-1,2-oxazole. Grades: > 95%. CAS No. 179162-55-1. Molecular formula: C21H21NO4. Mole weight: 351.4. | |
| (±)-Micozole-[d5] Nitrate (2,4-dichlorobenzyloxy-[d5]) | One of the isotopic labelled form of (±)-Micozole Nitrate, which could be used as an antifungal agent. Alternative Names: 1-[2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole Nitrate. Grades: 95% by HPLC; 98% atom D. CAS No. 1398065-80-9. Molecular formula: C18H10D5Cl4N3O4. Mole weight: 484.14. | |
| Micromelin | Micromelin is isolated from the herbs of Micromelum integerrimum. Uses: Anti-tumor; anti-cancer. Alternative Names: 7-methoxy-6-[(1S,4S,5S)-1-methyl-2-oxo-3,6-dioxabicyclo[3.1.0]hexan-4-yl]chromen-2-one. Grades: 98.5%. CAS No. 15085-71-9. Molecular formula: C15H12O6. Mole weight: 288.3. | |
| Milciclib | Milciclib is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2 / TRKA inhibitor PHA-848125 AC potently inhibits cyclin-dependent kinase 2 (CDK2) and exhibits activity against other CDKs including CDK1 and CDK4, in addition to TRKA. Inhibition of these kinases may result in cell cycle arrest and apoptosis of tumor cells that express these kinases. CDKs are serine / threonine kinases involved in regulation of the cell cycle and may be overexpressed in some cancer cell types. The neurotrophin receptor TRKA is mutated in a variety of cancer cell types. Alternative Names: PHA-848125; PHA848125; PHA 848125; PHA-848125AC; PHA 848125AC; PHA848125AC. Grades: >98%. CAS No. 802539-81-7. Molecular formula: C25H32N8O. Mole weight: 460.57. | |
| Milnacipran-[d5] hydrochloride | Milnacipran-[d5] hydrochloride is a labelled impurity of Milnacipran. Milnaciprana is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat fibromyalgia. Alternative Names: Milnacipran-d5 hydrochloride; Milnacipran-d5 HCl. Grades: > 95%. Molecular formula: C15H18ClN2OD5. Mole weight: 287.85. | |
| Mirabegron impurity 002 | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Alternative Names: 4-ethoxy-3-methoxybenzonitrile; 81259-56-5; SCHEMBL6944897; MFCD02256107; AKOS000198357; 4-ETHOXY-3-METHOXY-BENZONITRILE; CS-0319395; Z54794538. Grades: 95%. CAS No. 81259-56-5. Molecular formula: C10H11NO2. Mole weight: 177.20. | |
| Mirabegron impurity 003 | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Alternative Names: 4-fluoro-N-methyl-2-nitrobenzamide; SCHEMBL1668405; YLTRKOOKMIYJDB-UHFFFAOYSA-N; 1018983-85-1. Grades: 95%. CAS No. 1018983-85-1. Molecular formula: C8H7FN2O3. Mole weight: 198.15. | |
| Mirabegron Impurity 4 | Mirabegron Impurity 4 is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Alternative Names: N-(2-Amino-4-thiazolyl)acetyl Mirabegron; (R)-2-(2-Aminothiazol-4-yl)-N-(4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)-N-(2-hydroxy-2-phenylethyl)acetamide. Grades: > 95%. CAS No. 1684452-83-2. Molecular formula: C26H28N6O3S2. Mole weight: 536.67. | |
| Mirabegron Impurity 8 2HCl | meta-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Alternative Names: meta-Mirabegron dihydrochloride; 2-Amino-N-[3-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide dihydrochloride. Grades: > 95%. Molecular formula: C21H24N4O2S.2HCl. Mole weight: 469.43. | |
| Miriplatin | Miriplatin, a cyclohexane-1,2-diamine platinum(II) dimyristate, is a novel platinum complex that can be used to treat hepatocellular carcinoma (HCC). Alternative Names: Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)-, (SP-4-2)-; Platinum, (1,2-cyclohexanediamine-κN,κN')bis(tetradecanoato-κO)-, [SP-4-2-[1R-(trans)]]-; Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN,κN']bis(tetradecanoato-κO)-, (SP-4-2)-; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum; SM 11355; SM-11355; SM11355. CAS No. 141977-79-9. Molecular formula: C34H68N2O4Pt. Mole weight: 764.01. | |
| Mirodenafil Dihydrochloride | Mirodenafil dihydrochloride is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Alternative Names: 5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one Hydrochloride; 4-[[3-(5-Ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-1-piperazineethanol Dihydrochloride; Mirodenafil 2HCl; M-vix; SK 3530 dihydrochloride; SK3530 dihydrochloride; SK-3530 dihydrochloride. Grades: > 98%. CAS No. 862189-96-6. Molecular formula: C26H39Cl2N5O5S. Mole weight: 604.59. | |
| MitoBloCK-10 | MitoBloCK-10 is a first-in-class TIMM44 blocker that inhibits TIM44 binding to the precursor and to Hsp70. MitoBloCK-10 can attenuate protein-associated motor (PAM) complex activity. Alternative Names: 3-Fluoro-N'-((5-nitrothiophen-2-yl)methylene)benzohydrazide; 3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)methylidene]benzohydrazide. CAS No. 394694-98-5. Molecular formula: C12H8FN3O3S. Mole weight: 293.28. | |
| MitoTEMPOL | MitoTEMPOL. CAS No. 1101113-39-6. | |
| Mitoxantrone | Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Uses: Analgesics. Alternative Names: mitoxantrone; 65271-80-9; Mitoxanthrone; Mitozantrone; DHAQ. Grades: >98%. CAS No. 65271-80-9. Molecular formula: C22H28N4O6. Mole weight: 444.48. | |
| Mivebresib | Mivebresib is a BET inhibitor with potential antineoplastic activity. It disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Mivebresib is also a MYC and the TMPRSS2-ETS fusion proteins inhibitor. Mivebresib can inhibit cell growth in susceptible tumors. Uses: Anti-tumor. Alternative Names: ABBV-075; ABBV 075; ABBV075; Mivebresib;N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide. Grades: 98%. CAS No. 1445993-26-9. Molecular formula: C22H19F2N3O4S. Mole weight: 459.47. | |
| Mizagliflozin | Mizagliflozin is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine. It blocks intestinal glucose absorption and reduces GIP secretion in rats and humans, which suggests SGLT1 glucose transport is critical for GIP release. It is used for the treatment of diabetes. Alternative Names: DSP-3235, DSP3235; DSP 3235; KGA-3235; KGA 3235; KGA3235; GSK-1614235; GSK 1614235; GSK1614235. Grades: 98%. CAS No. 666843-10-3. Molecular formula: C28H44N4O8. Mole weight: 564.68. | |
| MK-1775 | MK-1775, also known as AZD-1775, is a WEE1 inhibitor and a small-molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2 / cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. Unlike normal cells, most p53-deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells. Annulment of the G2 checkpoint may therefore make p53-deficient tumor cells more vulnerable to antineoplastic agents and enhance their cytotoxic effect. Alternative Names: MK-1775; MK1775; MK 1775; AZD1775; AZD-1775; AZD 1775; adavosertib. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one. Grades: >98%. CAS No. 955365-80-7. Molecular formula: C27H32N8O2. Mole weight: 500.607. | |
| MK-2206 dihydrochloride | MK-2206 is a highly selective Akt inhibitor with IC50 of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. It is undergoing a phase II clinical trial for the treatment of ovarian, fallopian tube, or primary peritoneal cancer where there are mutations in P13K or AKT or low levels of PTEN. Alternative Names: MK-2206. MK 2206. MK2206. Grades: >98%. CAS No. 1032350-13-2. Molecular formula: C25H23Cl2N5O. Mole weight: 480.4. | |
| MK-4827 (R-enantiomer) | MK-4827 (R-enantiomer) is the R form of MK-4827, which is a PARP inhibitor developed for the treatment of ovarian cancer. Alternative Names: (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; Niraparib R-enantiomer; MK4827 R-enantiomer; MK 4827 R-enantiomer; MK-4827 R-enantiomer. Grades: > 98%. CAS No. 1038915-58-0. Molecular formula: C19H20N4O. Mole weight: 320.396. | |
| MK-8353 | MK-8353 is an orally available ERK1/2 inhibitor. It exhibited antitumor activity in patients with BRAFV600-mutant melanoma. Alternative Names: (3S)-3-(methylthio)-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide. CAS No. 1184173-73-6. Molecular formula: C37H41N9O3S. Mole weight: 691.84. | |
| MK-8722 | MK-8722 is a potent pan-AMPK activator that improves glucose homeostasis but induces cardiac hypertrophy. AMPK has long been of interest as a target for the treatment of Type 2 Diabetes Mellitus. Alternative Names: MK 8722; MK8722. CAS No. 1394371-71-1. Molecular formula: C24H20ClN3O4. Mole weight: 449.9. | |
| MKC-3946 | MKC-3946 is a potent inhibitor of inositol-requiring enzyme 1α (IRE1α). It inhibits XBP1 mRNA splicing and exhibits cytotoxicity against AML cells. MKC-3946 leads to modest growth inhibition in MM cells but has no effect on normal mononuclear cells in vitro. Alternative Names: MKC-3946; MKC 3946; MKC3946; 2-hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde. Grades: >98%. CAS No. 1093119-54-0. Molecular formula: C21H20N2O3S. Mole weight: 380.462. | |
| MKT 077 | MKT-077 is a cationic rhodacyanine dye. It shows antiproliferative activity against cancer cell lines with EC50s value of 1.4-2.2 μM in vitro through its ability to inhibit members of the heat shock protein 70 family of molecular chaperones. Alternative Names: MKT-077; MKT 077; MKT077; FJ-776; FJ 776; FJ776; 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride. Grades: ≥98% by HPLC. CAS No. 147366-41-4. Molecular formula: C21H22ClN3OS2. Mole weight: 432. | |
| ML204 | ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise with an IC(50) value of 0.96 μm and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation. Alternative Names: 4-Methyl-2-piperidin-1-ylquinoline; ML204; ML 204; ML-204. Grades: > 98%. CAS No. 5465-86-1. Molecular formula: C15H18N2. Mole weight: 226.323. | |
| ML241 | ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer. Uses: Anticancer. Alternative Names: 2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine; ML241; ML-241; ML 241. Grades: 98%. CAS No. 1346528-06-0. Molecular formula: C23H24N4O. Mole weight: 372.46. | |
| ML 297 | ML 297 is a Kir3.1/3.2 (GIRK1/2) channel activator with IC50 values of 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3. Alternative Names: ML297; ML 297; ML-297; N-(3,4-Difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea. Grades: ≥99% by HPLC. CAS No. 1443246-62-5. Molecular formula: C17H14F2N4O. Mole weight: 328.32. | |
| ML324 | ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. Alternative Names: ML-324; ML 324; ML324; CID-44143209; CID 44143209; CID44143209. Grades: >98%. CAS No. 1222800-79-4. Molecular formula: C21H23N3O2. Mole weight: 349.43. | |
| ML 67-33 | ML 67-33 is a K2P potassium channel activator that increases channel currents by activating core gating apparatus of channels. Alternative Names: 2,7-Dichloro-9,10-dihydro-9,9-dimethyl-10-[2-(2H-tetrazol-5-yl)ethyl]acridine. Grades: 97%. CAS No. 1443290-89-8. Molecular formula: C18H17Cl2N5. Mole weight: 374.27. | |
| MLN0128 | MLN0128, also known as INK128, is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt / mTOR signaling pathway, which is frequently dysregulated in human cancers. Alternative Names: TAK-228; TAK 228; TAK228; INK128; INK-128; INK 128; MLN0128; MLN 0128; MLN-0128; Sapanisertib. Grades: >98%. CAS No. 1224844-38-5. Molecular formula: C15H15N7O. Mole weight: 309.333. | |
| MMAD | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. Uses: Adcs cytotoxin. Alternative Names: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. Grades: ≥98.0% (HPLC). CAS No. 203849-91-6. Molecular formula: C41H66N6O6S. Mole weight: 771.06. | |
| Mogrol | Mogrol is a natural compound isolated from the fruits of Siraitia grosvenorii Swingle. Alternative Names: (23R)-cucurbit-5-ene-3beta,11alpha,23,25-tetraol. Grades: 98.5%. CAS No. 88930-15-8. Molecular formula: C30H52O4. Mole weight: 476.742. | |
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