BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| N,N'-Difurfuryloxamide | N,N'-Difurfuryloxamide, an organic compound of paramount significance used as a crucial forerunner in the creation of sundry medicines and pharmaceuticals. Distinguished by its notable anti-inflammatory and antimicrobial traits, it exhibits extensive promise as an agent amenable for treating multiple ailments like gingivitis and periodontitis. Alternative Names: N,N'-bis(furan-2-ylmethyl)ethanediamide; N,N'-difurfuryl-oxalamide. CAS No. 69010-90-8. Molecular formula: C12H12N2O4. Mole weight: 248.238. |  |
| N,N-Dimethyldecylamine N-oxide | N,N-Dimethyldecylamine N-oxide, commonly known as a tertiary amine oxide, is a surfactant used extensively in scientific research due to its unique properties as both a nonionic surfactant and a stabilizing agent in various aqueous and non-aqueous systems. Alternative Names: DDAO; Decylamine oxide; 1-Decanamine, N,N-dimethyl-, N-oxide; N,N-Dimethyldecylamine oxide; Capric dimethyl amine oxide. Grades: 98%. CAS No. 2605-79-0. Molecular formula: C12H27NO. Mole weight: 201.35. | |
| N,N-Dimethylhydroxylamine hydrochloride | N,N-Dimethylhydroxylamine hydrochloride is a versatile chemical compound used in scientific research. Alternative Names: N-Hydroxy-N,N-dimethylamine hydrochloride; Methanamine, N-hydroxy-N-methyl-, hydrochloride (9CI). Grades: ≥95%. CAS No. 16645-06-0. Molecular formula: C2H8ClNO. Mole weight: 97.54. | |
| N,N-Dimethyl-L-valine | N,N-Dimethyl-L-valine. Alternative Names: N,N-DIMETHYL-L-VALINE; N,N-Dimethylvaline99%. Grades: 95%. CAS No. 2812-32-0. Molecular formula: C7H15NO2. Mole weight: 145.2. | |
| N,N-dimethyloctadecanamide | N,N-dimethyloctadecanamide (CAS# 3886-90-6 ) is a useful research chemical. Alternative Names: N,N-Dimethyloctadecanamide; N N-Dimethyl-9-octadecenamide; Hallcomid M 18. Grades: 95 %. CAS No. 3886-90-6. Molecular formula: C20H41NO. Mole weight: 311.5. | |
| N-Nitroso Betahistine-[13C,d3] | N-Nitroso Betahistine-[13C,d3] is a labelled Betahistine impurity. Betahistine is a H1 receptor agonist, which serves as a vasodilator. Alternative Names: N-(methyl-13C-d3)-N-(2-(pyridin-2-yl)ethyl)nitrous amide; Betahistine impurity 5-13C,d3. Molecular formula: C7[13C]H8D3N3O. Mole weight: 169.21. | |
| N-Nitrosocytisine | N-Nitrosocytisine is a derivative of Cytisine, which is a nicotinic acetylcholine receptor (nAChR) agonist. Alternative Names: (1R,5R)-1,2,3,4,5,6-Hexahydro-3-nitroso-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one; 12-Nitrosocytisine; Nitrosocytisine; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-nitroso-, (1R,5R)-. Grades: ≥90%. CAS No. 19634-60-7. Molecular formula: C11H13N3O2. Mole weight: 219.24. | |
| N-Nitrosohexamethyleneimine | N-Nitrosohexamethyleneimine (CAS# 932-83-2 ) is a useful research chemical. Alternative Names: N-Nitrosoperhydroazepine; Nitrosohexamethylenimine. CAS No. 932-83-2. Molecular formula: C6H12N2O. Mole weight: 128.17. | |
| N-Nitroso Sertraline-[d3] | N-Nitroso Sertraline-[d3] is a deuterated compound of N-Nitroso Sertraline. N-Nitroso Sertraline is an impurity of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat certain mental disorders. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. | |
| N-Nitroso Tamsulosin | An impurity of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Alternative Names: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)(nitroso)amino)propyl)-2-methoxybenzenesulfonamide. Molecular formula: C20H27N3O6S. Mole weight: 437.51. | |
| N,N,N-Trimethyl-2,3-bis(octadec-9-en-1-yloxy)propan-1-aminium chloride | N,N,N-Trimethyl-2,3-bis(octadec-9-en-1-yloxy)propan-1-aminium chloride. Alternative Names: 1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; rac-DOTMA; N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium chloride; 1-Propanaminium, N,N,N-trimethyl-2,3-bis(9-octadecen-1-yloxy)-, chloride (1:1); 1-Propanaminium, N,N,N-trimethyl-2,3-bis(9-octadecenyloxy)-, chloride; 1-Propanaminium, N,N,N-trimethyl-2,3-bis(9-octadecenyloxy)-, chloride, (±)-; N,N,N-trimethyl-2,3-bis(9-octadecen-1-yloxy)-1-propanaminium, monochloride. Grades: ≥95%. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.59. | |
| N,N'-Thiobisphthalimide | N,N'-Thiobisphthalimide. Alternative Names: n,n'-thio-bis(phthalimide); N,N'-Thiodiphthalimide; 2,2'-thiobis(isoindoline-1,3-dione); 2-(1,3-dioxoisoindol-2-yl)sulfanylisoindole-1,3-dione. CAS No. 7764-29-6. Molecular formula: C16H8N2O4S. Mole weight: 324.31. | |
| Nodakenin | Nodakenin is an important natural resource and medicinal material with anti-allergic and anti-inflammatory activities. Alternative Names: (+)-Marmesinin. Grades: >98%. CAS No. 495-31-8. Molecular formula: C20H24O9. Mole weight: 408.4. | |
| N,O-Diacetate Isoacyclovir | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Alternative Names: N-Formyl Valacyclovir; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-formyl-L-valinate. Grades: > 95%. CAS No. 91702-60-2. Molecular formula: C12H15N5O5. Mole weight: 309.28. | |
| Nodosin | Nodosin is isolated from the herbs of Isodon serra. Uses: Anti-inflammatory; antibacterial; insect growth inhibitor. Alternative Names: Enmein,13-deoxy-5-hydroxy-, (5b)-;Enmein, 13-deoxy-5-hydroxy-, (5β)-. Grades: 98.5%. CAS No. 10391-09-0. Molecular formula: C20H26O6. Mole weight: 362.4. | |
| Nolatrexed dihydrochloride | Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Alternative Names: AG 337; Thymitaq; 2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone Hydrochloride; 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)-1,4-dihydroquinazolin-4-one dihydrochloride; 3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride. Grades: 98%. CAS No. 152946-68-4. Molecular formula: C14H14Cl2N4OS. Mole weight: 357.25. | |
| Nonacosan-15-one | Nonacosan-15-one (CAS# 2764-73-0 ) is a useful research chemical. Alternative Names: nonacosan-15-one; 15-Nonacosanone; Nonacosan-15-one; 2764-73-0; AC1L2PYV; AC1Q5H9Q. Grades: 95 %. CAS No. 2764-73-0. Molecular formula: C29H58O. Mole weight: 422.77. | |
| Nonoxynol-5 | Nonylbenzene-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker. Nonylbenzene-PEG5-OH can be used in the synthesis of a series of PROTACs. CAS No. 20636-48-0. Molecular formula: C25H44O6. Mole weight: 440.61. | |
| Noopept | Noopept is a nootropic and neuroprotective drug that normalizes the balance of the pro- and antioxidant systems. Noopept modulates a variety of physiological functions including cognition and anxiety. Noopept significantly weakens streptozotocin-Induced diabetes in rats. Alternative Names: GVS-111; GVS111; GVS 111; SGS-111; SGS 111; SGS111. Grades: >98%. CAS No. 157115-85-0. Molecular formula: C17H22N2O4. Mole weight: 318.37. | |
| Noradrenalone Hydrochloride | An impurity of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Alternative Names: 2-Amino-1-(3,4-dihydroxyphenyl)ethan-1-one HCl; 2-Amino-1-(3,4-dihydroxyphenyl)ethanone hydrochloride. Grades: > 95%. CAS No. 5090-29-9. Molecular formula: C8H9NO3.HCl. Mole weight: 203.62. | |
| Norbornane | Norbornane is a useful research chemical. Alternative Names: Norbornylane. CAS No. 279-23-2. Molecular formula: C7H12. Mole weight: 96.17. | |
| Norchelerythrine | Norchelerythrine is an alkaloid isolated from Chelidonium majus that exhibits antifeeding activity. Alternative Names: 1,2-dimethoxy-[1,3]benzodioxolo[5,6-c]phenanthridine. Grades: 98.0%. CAS No. 6900-99-8. Molecular formula: C20H15NO4. Mole weight: 333.343. | |
| Norfloxacin-[d5] | Norfloxacin-[d5] is the labelled analogue of Norfloxacin, which is a broad-spectrum antibiotic active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase. Norfloxacin can be used to treat urinary tract infections. Alternative Names: Norfloxacin-D5; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid-d5; Baccidal-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 1015856-57-1. Molecular formula: C16H13D5FN3O3. Mole weight: 324.36. | |
| (+/-)-Norgestrel-[d6] | (+/-)-Norgestrel-[d6] is the labelled analogue of Norgestrel. Norgestrel is a progestin that is used in combination with an estrogen in hormonal contraceptives. Alternative Names: (+/-)-Norgestrel-D6; (+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one-2,2,4,6,6,10-D6. Grades: ≥99% by HPLC; >98% atom D. Molecular formula: C21H22D6O2. Mole weight: 318.39. | |
| Norhyoscyamine sulfate | Norhyoscyamine sulfate, a potent anticholinergic agent, exerts its therapeutic effects through the inhibition of acetylcholine activity, which makes it a valuable treatment option for several types of gastrointestinal disorders, such as motility disorders, as well as urinary incontinence. Moreover, this multifaceted medication exhibits remarkable preoperative benefits, as it can effectively reduce both respiratory and digestive secretions, underscoring its versatility and potential for widespread clinical use. Alternative Names: Norhyoscyamine. CAS No. 537-29-1. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| (+)-Normacusine B | Tombozine is a natural alkaloid isolated from the herbs of Rauvolfia yunnanensis. Alternative Names: 10-deoxysarpagine. Grades: >98%. CAS No. 604-99-9. Molecular formula: C19H22N2O. Mole weight: 294.4. | |
| (+/-)-Norpropoxyphene-[d5] maleate | (+/-)-Norpropoxyphene-[d5] maleate is the labelled analogue of Norpropoxyphene, which is a major metabolite of the opioid analgesic drug dextropropoxyphene. Alternative Names: (+/-)-Norpropoxyphene maleate D5. Grades: 98% atom D. CAS No. 136765-47-4. Molecular formula: C25H26D5NO6. Mole weight: 446.55. | |
| Nortrachelogenin | Nortrachelogenin is a natural lignan found in the herbs of Trachelospermum jasminoides, it shows effects on the central nervous system producing depression in rabbits. Alternative Names: (+/-)-Nortrachelogenin; (3S)-4,5-Dihydro-4β-(4-hydroxy-3-methoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)-3β-hydroxyfuran-2(3H)-one. Grades: >97%. CAS No. 34444-37-6. Molecular formula: C20H22O7. Mole weight: 374.4. | |
| Norverapamil | Norverapamil is a metabolite of Verapamil. Verapamil is a medication used for the treatment of high blood pressure, chest pain from not enough blood flow to the heart, and supraventricular tachycardia. Norverapamil is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. Uses: Calcium channel blockers. Alternative Names: α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile; Verapamil EP Impurity J; Nor Verapamil; NSC672815. Grades: 95%. CAS No. 67018-85-3. Molecular formula: C26H36N2O4. Mole weight: 440.58. | |
| n-Propyl Dioxepin | N-Propyl Dioxepin, a chemical compound, has been found to hold immense potential in the field of neuroscience due to its ability to be leveraged in the creation of new pharmaceuticals that are aimed at treating a range of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. This compound has been shown to be a wonderfully proficient antagonist of the dopamine receptors, as evidenced by preclinical studies. Alternative Names: 2-Propyl-4,7-dihydro-1,3-dioxepine. CAS No. 4469-34-5. Molecular formula: C8H14O2. Mole weight: 142.198. | |
| N-Propylmaleimide | N-Propylmaleimide. Alternative Names: 1-Propyl-1H-pyrrole-2,5-dione; N-(n-propyl)maleimide. Grades: 95 %. CAS No. 21746-40-7. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| N-(pyridin-2-yl)pyridine-2-carbothioamide | N-(pyridin-2-yl)pyridine-2-carbothioamide. CAS No. 39122-38-8. | |
| N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide | N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Grades: 98.0%. Molecular formula: C22H16N6O2S. Mole weight: 428.474. | |
| NS-304 | NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Alternative Names: Selexipag; NS304; NS 304; ACT-293987; ACT293987; ACT 293987; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide. Grades: ≥95%. CAS No. 475086-01-2. Molecular formula: C26H32N4O4S. Mole weight: 496.6. | |
| NSC 23005 sodium | NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Alternative Names: NSC 23005 sodium; NSC23005 sodium; NSC-23005 sodium; 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1796596-46-7. Molecular formula: C13H16NNaO4S. Mole weight: 305.33. | |
| N-tert-Butylglycine Acid Chloride HCl | N-tert-Butylglycine Acid Chloride HCl (CAS# 915725-52-9 ) is a useful research chemical. Alternative Names: 2-(tert-butylamino)acetyl chloride hydrochloride; N-t-butylglycine acid chloride hydrochloride. Grades: 95 %. CAS No. 915725-52-9. Molecular formula: C6H12ClNO.HCl. Mole weight: 186.08. | |
| N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine | Block Copolymer Synthesis Using a Commercially Available NMP Inititator. Alternative Names: 2,2,5-Trimethyl-3-(1-phenylethoxy)-4-phenyl-3-azahexane, Alkoxyamine NMP initiator. CAS No. 227000-59-1. Molecular formula: C22H31NO. Mole weight: 325.49. | |
| N-Tetradecylpropane-1,3-diamine | N-Tetradecylpropane-1,3-diamine is a useful research chemical. Alternative Names: N-tetradecylpropanediamine; (3-aminopropyl)(tetradecyl)amine; N-tetradecyl propane diamine. Grades: 95 %. CAS No. 4317-79-7. Molecular formula: C17H38N2. Mole weight: 270.501. | |
| N-trans-Feruloyl-3-methoxytyramine | N-Feruloyl-3-methoxytyramine is extracted from the roots of Litsea hypophaea. Alternative Names: N-trans-Feruloyl-3-O-methyldopamine. Grades: >97%. CAS No. 78510-19-7. Molecular formula: C19H21NO5. Mole weight: 343.4. | |
| NU7441 | NU7441 is a highly potent and selective DNA-PK inhibitor (IC50=14 nM), exhibiting ATP-competitive inhibition kinetics. NU7441 increased the cytotoxicity of ionizing radiation and etoposide in SW620, LoVo, and V3-YAC cells but not in V3 cells, confirming that potentiation was due to DNA-PK inhibition. NU7441 substantially retarded the repair of ionizing radiation-induced and etoposide-induced DSB. NU7441 appreciably increased G(2)-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. In mice bearing SW620 xenografts, NU7441 concentrations in the tumor necessary for chemopotentiation in vitro were maintained for at least 4 hours at nontoxic doses. NU7441 increased etoposide-induced tumor growth delay 2-fold without exacerbating etoposide toxicity to unacceptable levels. In conclusion, NU7441 shows sufficient proof of principle through in vitro and in vivo chemosensitization and radiosensitization to justify further development of DNA-PK inhibitors for clinical use. Alternative Names: NU7441; NU-7441; NU 7441; KU-57788; KU 57788; KU57788. Grades: 98%. CAS No. 503468-95-9. Molecular formula: C25H19NO3S. Mole weight: 413.49. | |
| Nuchensin | Nuchensin is a natural product found in Lantana montevidensis. Alternative Names: 5,6,3'-Trihydroxy-7,4'-dimethoxyflavone; 3',5,6-Trihydroxy-4',7-dimethoxyflavone. Grades: 98%. CAS No. 25782-24-5. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| Nucleozin | Nucleozin is a cell-permeable isoxazolylpiperazine, which targets influenza a nucleoprotein (NP) to inhibit influenza A H1N1, H3N2 and H5N1. Alternative Names: 1-(2-Chloro-4-nitrophenyl)-4-[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]-piperazine; [4-(2-Chloro-4-nitro-phenyl)-piperazin-1-yl]-(5-methyl-3-phenyl-isoxazol-4-yl)-methanone. Grades: ≥98%. CAS No. 341001-38-5. Molecular formula: C21H19ClN4O4. Mole weight: 426.85. | |
| Nusinersen sodium | Nusinersen sodium. | |
| Nutlin-3 | Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 μM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches. Alternative Names: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one. Grades: >98%. CAS No. 548472-68-0. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. | |
| Nutlin-3b | Nutlin-3b, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. Alternative Names: Nutlin-3; nutlin 3; Nutlin 3b; FJA1772CVW; (+)-Nutlin-3; CHEMBL2152332; CHEBI:46742; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one; 2-Piperazinone, 4-(((4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1H-imidazol-1-yl)carbonyl)-; 4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one; 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone; cis-4-{[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl}piperazin-2-one. Grades: >98%. CAS No. 675576-97-3. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. | |
| N-Vanillyldecanamide | N-Vanillyldecanamide is found in the fruits of Capsicum annuum L. var. annuum. Alternative Names: Decylic acid vanillylamide. Grades: > 95%. CAS No. 31078-36-1. Molecular formula: C18H29NO3. Mole weight: 307.43. | |
| NVP-BGJ398 phosphate | Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Alternative Names: Infigratinib phosphate; BGJ-398 phosphate; NVP-BGJ398 phosphate; NVPBGJ398 phosphate. Grades: >98%. CAS No. 1310746-10-1. Molecular formula: C26H34Cl2N7O7P. Mole weight: 658.47. | |
| NVP-BSK805 | NVP-BSK805, a quinoxaline derivative, is a selective ATP-competitive JAK2 inhibitor which could induce apoptosis (GI50 < 100 nM) and restrain the growth of JAK2V617F cells (Ba/F3). Alternative Names: 4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine; BSK 805; 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline. Grades: 98%. CAS No. 1092499-93-8. Molecular formula: C27H28F2N6O. Mole weight: 490.55. | |
| Nyasol | Nyasol is purified from the rhizomes of Anemarrhena asphodeloides. Nyasol may have the potential to be developed as a medicine for the treatment of allergies by inhibiting the activation of mast cells. Nyasol has antifungal activity and suppresses the Phytophthora blight on pepper plants. Alternative Names: Cis-Hinokiresinol. Grades: 98.0%. CAS No. 96895-25-9. Molecular formula: C17H16O2. Mole weight: 252.31. | |
| o-(1-Phenylethyl)phenol | o-(1-Phenylethyl)phenol. Alternative Names: 2-(1-Phenylethyl)phenol. CAS No. 4237-44-9. Molecular formula: C14H14O. Mole weight: 198.26. | |
| Obatoclax mesylate | Obatoclax mesylate is the mesylate salt of obatoclax, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl-2 protein family, preventing the binding of these anti-apoptotic proteins to the pro-apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl-2-overexpressing cells. The Bcl-2 family of proteins (bcl-2, bcl-xl, bcl-w, and Mcl-1) are overexpressed in a wide variety of cancers, including those of the lymphatic system, breast, lung, prostate, and colon. Alternative Names: (2E)-2-[(5Z)-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxypyrrol-2-ylidene]indole methanesulfonic acid. Grades: >98%. CAS No. 803712-79-0. Molecular formula: C20H19N3O.CH4O3S. Mole weight: 413.492. | |
| Obeticholic Acid | Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM. It reduced liver fat and reverted cholestasis in a rat model. Alternative Names: 6-ECDCA; 6-Ethylchenodeoxycholic acid; Obeticholic acid; INT 747; INT-747; INT747; 6-ECDCA; Ocaliva; (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Grades: >98%. CAS No. 459789-99-2. Molecular formula: C26H44O4. Mole weight: 420.634. | |
| Obicetrapib | Obicetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors can increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may help reduce the risk of cardiovascular disease. Alternative Names: 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-ethyl ester, (2R,4S)-; 1-Ethyl (2R,4S)-4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-1(2H)-quinolinecarboxylate; (2R,4S)-4-[[3,5-Bis(trifluoromethyl)benzyl][5-(3-carboxypropoxy)pyrimidin-2-yl]amino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester; AMG-899; AMG 899; AMG899; TA-8995; TA8995; TA 8995; DEZ-001; DEZ 001; DEZ001; Obicetrapib (free base). Grades: ≥98%. CAS No. 866399-87-3. Molecular formula: C32H31F9N4O5. Mole weight: 722.60. | |
| Oblongine | Oblongine is isolated from the roots of Stephania tetrandra. Alternative Names: (S)-1,2,3,4-Tetrahydro-8-hydroxy-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethylisoquinolinium; (1S)-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-8-ol. Grades: 95%. CAS No. 60008-01-7. Molecular formula: C19H24NO3. Mole weight: 314.4. | |
| Obtucarbamate A | Obtucarbamate A is an alkaloid compound found in the herbs of Dracaena sanderiana. Obtucarbamate A shows antitussive activity. Uses: Antitussive. Alternative Names: Dimethyl 4-methylbenzene-1,3-dicarbamate;Dimethyl toluene-2,4-dicarbamate. Grades: >98%. CAS No. 6935-99-5. Molecular formula: C11H14N2O4. Mole weight: 238.2. | |
| Octaarginine Trifluoroacetate | Octaarginine Trifluoroacetate. | |
| Octadecyl salicylate | Octadecyl salicylate. Alternative Names: octadecyl salicylate; 2-Hydroxybenzoic acid octadecyl ester; Salicylic acid octadecyl ester. Grades: 95%. CAS No. 14971-14-3. Molecular formula: C25H42O3. Mole weight: 390.59918. | |
| Octaethylene glycol diglycidyl ether | Octaethylene glycol diglycidyl ether is utilized primarily in polymer chemistry as a crosslinking agent and a reactive diluent in epoxy resin formulations. Alternative Names: PEG8 diglycidyl ether; 1,27-Di(oxiran-2-yl)-2,5,8,11,14,17,20,23,26-nonaoxaheptacosane. Grades: ≥95%. CAS No. 33918-21-7. Molecular formula: C22H42O11. Mole weight: 482.57. | |
| Octahydro-1H-1,4,7-triazonine Trihydrochloride | Octahydro-1H-1,4,7-triazonine Trihydrochloride, a chemical compound utilized in drug discovery, exhibits neuroprotective properties. It is regarded as a potent NMDA receptor antagonist, and preclinical evaluations suggest its potential for treating afflictions such as epilepsy and Alzheimer's disease. The compound's effectiveness in targeting these and other neurological disorders has piqued the interest of scientists with promising results. Alternative Names: 1,4,7-Triazacyclononane Trihydrochloride; 1H-1,4,7-Triazonine, octahydro-, trihydrochloride. Grades: ≥96%. CAS No. 58966-93-1. Molecular formula: C6H18Cl3N3. Mole weight: 238.59. | |
| Octa(OtBu)-Glu-OtBu | An intermediate in the synthesis of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. Alternative Names: L-Glutamic acid, N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-, 1-(1,1-dimethylethyl) ester. CAS No. 1188328-39-3. Molecular formula: C31H57NO7. Mole weight: 555.79. | |
| octylazanium acetate | octylazanium acetate (CAS# 2016-40-2 ) is a useful research chemical. Alternative Names: octylamine acetate. CAS No. 2016-40-2. Molecular formula: C10H23NO2. Mole weight: 189.3. | |
| O-Demethylforbexanthone | O-Demethylforbexanthone isolated from the herbs of Garcinia cowa. Alternative Names: 7,9,12-trihydroxy-2,2-dimethylpyrano[3,2-b]xanthen-6-one. Grades: 98.5%. CAS No. 92609-77-3. Molecular formula: C18H14O6. Mole weight: 326.3. | |
| O-Desbromo-pyrimidinyl Macitentan | An impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Alternative Names: N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide; N-5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl-N'-propylsulfamide. Grades: 98%. CAS No. 1393813-43-8. Molecular formula: C15H19BrN4O4S. Mole weight: 431.30. | |
| O-Desmethyl Venlafaxine Cyclic Impurity | O-Desmethyl Venlafaxine Cyclic Impurity is a cyclic impurity of O-Desmethylvenlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Alternative Names: 5-(4-Hydroxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane; 4-(3-Methyl-1-oxa-3-azaspiro[5.5]undecanyl)phenol. CAS No. 1346601-55-5. Molecular formula: C16H23NO2. Mole weight: 261.37. | |
| ODM-201 | ODM-201 is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR. Alternative Names: ODM-201; ODM 201; ODM201. Grades: 98%. CAS No. 1297538-32-9. Molecular formula: C19H19ClN6O2. Mole weight: 389.85. | |
| ODN 1018 sodium | ODN 1018 sodium. | |
| Odorinol | Odorinol is isolated from the herbs of Aglaia odorata. It inhibits both the initiation and promotion stages of two-stage skin carcinogenesis. Alternative Names: Butanamide, 2-hydroxy-2-methyl-N-(1-(1-oxo-3-phenyl-2-propenyl)-2-pyrrolidinyl)-, (S-(R*,S*-(E)))-; (+)-Odorinol. Grades: 95.5%. CAS No. 72755-22-7. Molecular formula: C18H24N2O3. Mole weight: 316.4. | |
| Officinalisinin I | Officinalisinin I is extracted from the rhizomes of Anemarrhena asphodeloides Bunge. Alternative Names: (3beta,5beta,22alpha)-26-(beta-D-Glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 57944-18-0. Molecular formula: C45H76O19. Mole weight: 921.1. | |
| Ofloxacin-[d3] | Ofloxacin-[d3] is the labelled analogue of Ofloxacin, which is a fluoroquinolone antibacterial agent. Alternative Names: Ofloxacin-D3; 8-Fluoro-3-methyl-9-(4-methyl-D3-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-azaphenalene-5-carboxylic acid; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid-d3; Ofloxacine-d3; Exocin-d3; Flobacin-d3; Floxil-d3; Floxin-d3; Monoflocet-d3; Ocuflox-d3; Ofloxacin D3 (N-methyl D3). Grades: 95% by HPLC; 98% atom D. CAS No. 1173147-91-5. Molecular formula: C18H17D3FN3O4. Mole weight: 364.39. | |
| Ohchinolide B | Ohchinolide B is a naturally occurring metabolite isolated from A. indica. Grades: 95%. CAS No. 71902-49-3. Molecular formula: C35H44O10. Mole weight: 624.73. | |
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