BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Pemetrexed Impurity E Disodium Salt | An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Alternative Names: (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid sodium. Grades: >95%. CAS No. 937370-10-0. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38. |  |
| Penduletin | Penduletin is isolated from the leaves of Laggera pterodonta. It significantly reduces the production of TGF-β1, and has strong activity against EV71 who has low cytotoxicity in vitro. Uses: Antiviral; antitumor cells activity. Alternative Names: 3,6,7-Trimethyl-6-hydroxykaempferol. Grades: 98%. CAS No. 569-80-2. Molecular formula: C18H16O7. Mole weight: 344.3. | |
| Penicillanic Acid Sodium Salt | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Alternative Names: Sulbactam Impurity 2 Sodium Salt. CAS No. 4027-62-7. Molecular formula: C8H10NO3S.Na. Mole weight: 223.23. | |
| Pentamethylcyclopentadienylbis(triphenylphosphine)ruthenium(II) chloride | Pentamethylcyclopentadienylbis(triphenylphosphine)ruthenium(II) chloride (CAS# 92361-49-4 ) is a useful research chemical. Alternative Names: Chloro(pentamethylcyclopentadienyl)bis(triphenylphosphine)ruthenium(II), Cp*RuCl(PPh3)2. CAS No. 92361-49-4. Molecular formula: [(C10H15)Ru(P((C6H5)3))2Cl]. Mole weight: 796.32. | |
| Pentylamine-6-carboxyltetramethylrhodamine TFA salt | Pentylamine-6-carboxyltetramethylrhodamine TFA salt, also called Xanthylium, 9-[5-[[(5-aminopentyl)amino]carbonyl]-2-carboxyphenyl]-3,6-bis(dimethylamino)-, inner salt, is a novel molecular rhodamine-type fluorescent probe. Uses: A novel molecular rhodamine-type fluorescent probe. Alternative Names: Xanthylium, 9-[5-[[(5-aminopentyl)amino]carbonyl]-2-carboxyphenyl]-3,6-bis(dimethylamino)-, inner salt. Grades: ≥ 97.0%. CAS No. 709025-58-1. Molecular formula: C30H34N4O4. Mole weight: 514.62. | |
| Pentyl phenoxyacetate | Pentyl phenoxyacetate. Alternative Names: Phenoxyacetic acid pentyl ester. CAS No. 74525-52-3. Molecular formula: C13H18O3. Mole weight: 222.28. | |
| PEPA | 2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats. Alternative Names: 2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide. Grades: >98%. CAS No. 141286-78-4. Molecular formula: C16H16F2N2O4S2. Mole weight: 402.44. | |
| Pepluanin A | Pepluanin A, isolated from the herbs of Euphorbia pekinensis Rupr, showed a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport. Alternative Names: 3-Pyridinecarboxylic acid, (2R,3R,3aS,4R,6S,7S,8S,10E,12S,13S,13aR)-2,4,6,7,13-pentakis(acetyloxy)-3-(benzoyloxy)-2,3,3a,4,5,6,7,8,9,12,13,13a-dodecahydro-13a-hydroxy-2,9,9,12-tetramethyl-5-methylene-1H-cyclopentacyclododecen-8-yl ester. Grades: >98%. CAS No. 670257-89-3. Molecular formula: C43H51NO15. Mole weight: 821.9. | |
| PERAKINE | Perakine is isolated from the root of Rauvolfia verticillata. Alternative Names: (13R)-13-Acetyloxy-7aα,2α,6α-ethan[1]yl[2]ylidene-1,2,3,4,6,7,7a,12bβ-octahydro-4α-methylindolo[2,3-a]quinolizine-3β-carbaldehyde; (17R,20α)-19-Oxo-1,2-didehydro-1-demethyl-21β-methyl-18-norajmalan-17-ol acetate. Grades: 98%. CAS No. 4382-56-3. Molecular formula: C21H22N2O3. Mole weight: 350.4. | |
| Peretinoin | Peretinoin, also known as NIK-333, orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells. Alternative Names: Peretinoin; NIK-333; NIK 333; NIK333. Grades: 99.79%. CAS No. 81485-25-8. Molecular formula: C20H30O2. Mole weight: 302.458. | |
| Perfluoro(4-methylpent-2-ene) | Perfluoro(4-methylpent-2-ene) is an exceptional compound with diverse applications, particularly in the fabrication of various fluorinated polymers and resins like the ubiquitous Teflon. Furthermore, this specialty chemical is indispensable in the pharmaceutical and electronics industries. It holds immense potential in the synthesis of surfactants as well. Nonetheless, there is limited knowledge on its therapeutic benefits against drugs or pathologies. Alternative Names: perfluoro(4-methyl-2-pentene). Grades: 95%. CAS No. 2070-70-4. Molecular formula: C6F12. Mole weight: 300.05. | |
| Perifosine | Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. Alternative Names: KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; D21266; D-21266N; N-Dimethylpiperidinium-4-yl(octadecyl)phosphate; 1,1-Dimethyl-4-[[(octadecyloxy)hydroxyphosphoryl]oxy]piperidinium inner salt. Grades: >98%. CAS No. 157716-52-4. Molecular formula: C25H52NO4P. Mole weight: 461.668. | |
| Perindopril Related Compound 1 HCl | An impurity of Perindopril which is a potent vasoconstrictor in the renin-angiotensin-aldosterone system (RAAS). Alternative Names: (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride; (2S,3aR,7aS)-1H-Octahydroindole-2-carboxylic acid hydrochloride; 1H-Indole-2-carboxylic acid, octahydro-, hydrochloride (1:1), (2S,3aR,7aS)-; (2S,3aR,7aS)-2,3,3a,4,5,6,7,7a-octahydro-1H-indole-2-carboxylic acid; hydrochloride; (2S,3aR,7aS)-1H-octahydroindole-2-carboxylic acid HCl; PONAUWFRJYNGAC-MWDCIYOWSA-N; (2S,3aR,7aS)-Octahydro-indole-2-carboxylic acid hydrochloride; SCHEMBL1041576; DTXSID60647571; AMY14951; FD7233; AKOS015915339; AC-8816; (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid--hydrogen chloride (1/1). Grades: > 95%. CAS No. 144540-75-0. Molecular formula: C9H15NO2.HCl. Mole weight: 205.69. | |
| Periplocogenin | Periplocogenin is a steroid isolated from Periploca sepium. Grades: 98.0%. CAS No. 112899-63-5. Molecular formula: C28H42O6. Mole weight: 474.638. | |
| Periplocoside O | Periplocoside O is a steroid isolated from Periplocae Cortex. Grades: 98.0%. CAS No. 116709-67-2. Molecular formula: C36H56O10. Mole weight: 648.834. | |
| Peucedanol | Peucedanol is an intriguing biologically active constituent originating from the diverse Peucedanum plants, aiding in studying inflammation encompassing rheumatoid arthritand asthma. Alternative Names: 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-7-hydroxychromen-2-one. Grades: 98.5%. CAS No. 20516-23-8. Molecular formula: C14H16O5. Mole weight: 264.277. | |
| Pevonedistat | Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. Uses: Enzyme inhibitors. Alternative Names: TAK-924; TAK 924; TAK924; MLN4924; MLN 4924; BAY-73-4506; BAY 73-4506; BAY73-4506. Grades: ≥98% (HPLC). CAS No. 905579-51-3. Molecular formula: C21H25N5O4S. Mole weight: 443.52. | |
| Pexidartinib | Pexidartinib. CAS No. 1029044-16-3. | |
| Pexidartinib hydrochloride | Pexidartinib is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM. Alternative Names: Pexidartinib HCl; PLX3397 HCl; PLX 3397 HCl; PLX-3397 HCl. CAS No. 2040295-03-0. Molecular formula: C20H16Cl2F3N5. Mole weight: 454.28. | |
| Pexmetinib | Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. It has potential antineoplastic, anti-inflammatory, and antiangiogenic activities. It inhibits other kinases including vascular endothelial growth factor receptor (VEGFR2) and Src tyrosine kinases. Alternative Names: 1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea; Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]-; N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]urea; ARRY 614; ARRY-614; ARRY614; N-(3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-yl)-N'-[5-fluoro-2-[1-(2-hydroxyethyl)-1H-indazol-5-yloxy]benzyl]urea. Grades: 98%. CAS No. 945614-12-0. Molecular formula: C31H33FN6O3. Mole weight: 556.63. | |
| PF-04418948 | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Alternative Names: PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948. Grades: 98%. CAS No. 1078166-57-0. Molecular formula: C23H20FNO5. Mole weight: 409.41. | |
| PF-04457845 | PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen. Alternative Names: PF-04457845; PF 04457845; PF04457845; PF-4457845; PF 4457845; PF4457845. Grades: >98%. CAS No. 1020315-31-4. Molecular formula: C23H20F3N5O2. Mole weight: 455.43. | |
| PF-04691502 | PF-04691502 is an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K / mTOR signaling pathway, with potential antineoplastic activity. It inhibits both PI3K and mTOR kinases, which may result in apoptosis and growth inhibition of cancer cells overexpressing PI3K / mTOR. Activation of the PI3K / mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy. mTOR, a serine / threonine kinase downstream of PI3K, may also be activated independent of PI3K. Alternative Names: PF04691502; PF 04691502; PF-04691502; PF4691502; PF 4691502; PF-4691502; 2-amino-8-((1R,4R)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 98%. CAS No. 1013101-36-4. Molecular formula: C22H27N5O4. Mole weight: 425.489. | |
| PF-06282999 | PF-06282999 is a selective myeloperoxidase Inhibitor originate by Pfizer. It showed good oral pharmacokinetics in preclinical species and robust irreversible inhibition of plasma MPO activity. In Mar 2015, Pfizer terminated phase I trial for the treatment of Acute coronary syndromes in Healthy volunteers in USA. Uses: Acute coronary syndromes. Alternative Names: PF-06282999; PF06282999; PF06282999. 2-(6-(5-chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide. Grades: 98%. CAS No. 1435467-37-0. Molecular formula: C13H12ClN3O3S. Mole weight: 325.77. | |
| PF-1355 | PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MPO without disrupting a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. PF-1355 was used to test the hypothesis that MPO activity is a critical mediator of disease activity in immune complex vasculitis mouse models, and to support the confidence in rationale for this mechanism as a therapeutic approach to treat related human condition such as alleviating tissue injury caused by Goodpasture syndrome and pulmonary vasculitis induced by immune complexes. Alternative Names: 2-(6-(2,5-dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide;PF-06281355; PF 06281355; PF06281355; PF-1355; PF 1355; PF1355. CAS No. 1435467-38-1. Molecular formula: C14H15N3O4S. Mole weight: 321.35. | |
| PF-3084014 | PF-3084014 is a selective γ-secretase inhibitor (IC50 = 6.2 nM in a cell-free assay). It has been shown to inhibit self-renewal and proliferation of cancer stem cells. Alternative Names: Nirogacestat; PF 3084014; PF3084014. Grades: >98%. CAS No. 1290543-63-3. Molecular formula: C27H41F2N5O. Mole weight: 489.66. | |
| PF-4136309 | PF-4136309 is a potent, selective, and orally bioavailable antagonist of CCR2, a chemokine receptor of the super family of seven-transmembrane G-protein-coupled receptors (GPCRs). Alternative Names: (S)-N-(2-(3-((4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide; PF4136309; PF 4136309; PF04136309; PF-04136309; INCB8761; INCB 8761; INCB-8761. CAS No. 1341224-83-6. Molecular formula: C29H31F3N6O3. Mole weight: 568.59. | |
| PF 429242 dihydrochloride | PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice. Alternative Names: PF-429242 dihydrochloride; PF429242 dihydrochloride. Grades: ≥97% by HPLC. CAS No. 2248666-66-0. Molecular formula: C25H35N3O2·2HCl. Mole weight: 482.49. | |
| PF-431396 | PF-431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Alternative Names: PF-431396; PF 431396; PF431396. Grades: >98%. CAS No. 717906-29-1. Molecular formula: C22H21F3N6O3S. Mole weight: 506.5. | |
| PF-562271 | PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Alternative Names: PF-562271; PF 562271; PF562271. Grades: >98%. CAS No. 717907-75-0. Molecular formula: C21H20F3N7O3S. Mole weight: 507.49. | |
| PF-670462 | PF-670462 is a potent and selective inhibitor of CK1ε in isolated enzyme preparations. It inhibits PER protein nuclear translocation causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo. It less effectively inhibits a wide variety of related or common kinases. It disrupts circadian rhythms in cells and animals and blocks the locomotor response to amphetamines in mice. It remains unclear whether one of the kinases has a predominant role in regulating the circadian clock. Alternative Names: PF-670462; PF 670462; PF670462;PF-670462 HCl; PF-670462 hydrochloride. Grades: >98%. CAS No. 950912-80-8. Molecular formula: C19H22Cl2FN5. Mole weight: 410.32. | |
| PFI-2 hydrochloride | PFI-2 hydrochloride is a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM) and is approximately 1,000-fold selective over a panel of 18 other methyltransferases. Besides, following activation of the Hippo signaling pathway in MCF7 cells it inhibits. Alternative Names: PFI-2 hydrochloride; PFI 2 hydrochloride; PFI2 hydrochloride; 8-fluoro-N-[(2R)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.98. | |
| PFI-3 | PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Alternative Names: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38. | |
| PFK15 | PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Alternative Names: PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one. Grades: >98%. CAS No. 4382-63-2. Molecular formula: C17H12N2O. Mole weight: 260.29. | |
| Phaseollidin | Phaseollidin, also called 3,9-Dihydroxy-10-prenylpterocarpan, is a natural flavonoid isolated from the fruits of Phaseolus vulgaris. Phaseollidin exhibits the activity of antimicrobial. Uses: Anti-microbial. Alternative Names: 3,9-Dihydroxy-10-prenylpterocarpan. Grades: >98%. CAS No. 37831-70-2. Molecular formula: C20H20O4. Mole weight: 324.4. | |
| Phellodendrine | Phellodendrine was effective in crescentic-type anti-GBM nephritis and the antinephritic mechanisms of this agent may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. Uses: Anti-inflammatory. Alternative Names: phellodendrine; Phellodendrine chloride. Grades: >98%. CAS No. 6873-13-8. Molecular formula: C20H24NO4. Mole weight: 342.4. | |
| Phellodendrine chloride | Phellodendrine chloride can be found in the peel of Phellodendron amurense Rupr. Phellodendrine was effective in crescentic-type anti-GBM nephritis and the antinephritic mechanisms of this agent may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. Uses: Hypoglycemic / anti-virus. Alternative Names: 6H-Dibenzo[a,g]quinolizinium,5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, chloride (1:1), (7S,13aS)-. Grades: >98%. CAS No. 104112-82-5. Molecular formula: C20H24NO4.Cl. Mole weight: 377.85. | |
| Phenoxazine | Phenoxazine. Alternative Names: Phenoxazine. CAS No. 135-67-1. Molecular formula: C12H9NO. Mole weight: 183.21. | |
| (±)-Phenoxybenzamine-[d5] HCl (benzyl-[2,3,4,5,6-d5]) | One of the isotopic labelled form of (±)-Phenoxybenzamine HCl, which is an α-antagonist and could be used as an ahypertensive agent. Alternative Names: N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine HCl. Grades: 95% by HPLC; 98% atom D. CAS No. 1398065-71-8. Molecular formula: C18H18D5Cl2NO. Mole weight: 345.32. | |
| phensuximide | Phensuximide is an anticonvulsant drug. It can be used for the treatment of neurological disorders stemming from the brain. Phensuximide can suppress the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. Uses: Anticonvulsant. Alternative Names: N-Methyl-2-phenyl-succinimide; (±)-Phensuximide; 1-Methyl-3-phenyl-2,5-pyrrolidinedione; 1-Methyl-3-phenylsuccinimide; Epimid; Lifene; Milontin; Milonton; Mirontin; N-Methyl-2-phenylsuccinimide; N-Methyl-3-phenylpyrrolidinedione; N-Methyl-3-phenylsuccinimide; N-Methyl-α-phenylsuccinimide; PM 334; Phensuximid; Phensuximide; RS-Phensuximide; Racemic Phensuximide; Succitimal. Grades: 95%. CAS No. 86-34-0. Molecular formula: C11H11NO2. Mole weight: 189.21. | |
| phenyl(1h-pyrrol-2-yl)methanone | Phenyl(1H-pyrrol-2-yl)methanone, a chemical entity utilized in the biomedicine domain as an intermediary in the preparation of drugs, exhibits promising anti-tumor properties and is being studied intensively for its potential in tackling diverse types of cancers. Its multifaceted therapeutic capabilities entail a comprehensive investigation aimed at establishing its clinical effectiveness. Alternative Names: 2-Benzoylpyrrole; 2-Benzoyl-1H-pyrrole; Methanone, phenyl-1H-pyrrol-2-yl-. Grades: 98%. CAS No. 7697-46-3. Molecular formula: C11H9NO. Mole weight: 171.19. | |
| Phenyl 2-hydroxy-4,5-dimethoxybenzoate | Phenyl 2-hydroxy-4,5-dimethoxybenzoate is an impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Alternative Names: 2-Hydroxy-4,5-dimethoxybenzoic acid phenyl ester; Benzoic acid, 2-hydroxy-4,5-dimethoxy-, phenyl ester; Acotiamide Impurity 35. Grades: ≥98%. CAS No. 877997-98-3. Molecular formula: C15H14O5. Mole weight: 274.27. | |
| Phenylboronic Acid-[d5] | Phenylboronic Acid-[d5] is the labelled analogue of Phenylboronic Acid, which is a compound used in organic synthesis of various pharmaceutical goods. Alternative Names: Phenyl-d5-boronic acid; B-Phenylboronic Acid-d5; Dihydroxyphenylborane-d5; Phenylboric Acid-d5; Phenyldihydroxyborane-d5; B-(Phenyl-2,3,4,5,6-d5)boronic Acid; (Pentadeuterophenyl)boronic Acid. Grades: 98% by CP; 98% atom D. CAS No. 215527-70-1. Molecular formula: C6H2D5BO2. Mole weight: 126.96. | |
| Phenylethanolamine A-[d3] | Phenylethanolamine A-[d3] is a labelled Phenylethanolamine A, which is a beta agonist. Alternative Names: 1-(4-Methoxy-D3-phenyl)-2-[1-methyl-3-(4-nitro-phenyl)-propylamino]-ethanol. Grades: 95% by HPLC; 98% atom D. Molecular formula: C19H21D3N2O4. Mole weight: 347.42. | |
| Phenyl methylcarbamate | Phenyl methylcarbamate can be used as a biomarker of colorectal cancer. It also used as an insecticide. Alternative Names: Methylcarbamic acid phenyl ester; NSC 128138; Phenmec; N-Methylphenylcarbamate; Phenyl monomethylcarbamate; Carbamic acid, methyl-, phenyl ester; Phenol, methylcarbamate; Carbamic acid, N-methyl-, phenyl ester. Grades: ≥95%. CAS No. 1943-79-9. Molecular formula: C8H9NO2. Mole weight: 151.16. | |
| Phenytoin EP Impurity D | An impurity of Phenytoin which is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. Alternative Names: Diphenylglycoluril; Phenytoin Impurity D; 3a,6a-Diphenylglycouril; Tetrahydro-3a,6a-diphenyl-iMidazo[4,5-d]iMidazole-2,5(1H,3H)-dione. Grades: 98%. CAS No. 5157-15-3. Molecular formula: C16H14N4O2. Mole weight: 294.31. | |
| Phlogacantholide B | Phlogacantholide B is extracted from the roots of Phlogacanthus curviflorus. Alternative Names: (4R,4aS,7S,10aR,11bR)-7-hydroxy-4-(hydroxymethyl)-4,8,11b-trimethyl-2,3,4a,5,6,7,10a,11-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one. Grades: 98.5%. CAS No. 830347-16-5. Molecular formula: C20H28O4. Mole weight: 332.44. | |
| Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt | The chemical compound, Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt, is a complex and multifaceted substance extensively utilized in the biomedical field for investigating ailments related to glycolysis, such as cancer and diabetes. Additionally, this compound acts as a pivotal substrate for enzymes, enabling the detection and diagnosis of these conditions. Alternative Names: Phosphoenolpyruvic Acid tris(Cyclohexylammonium) Salt; 2-(Phosphonooxy)-2-propenoic acid tri(cyclohexylammonium) salt; PEP-3CHA. Grades: ≥98%. CAS No. 35556-70-8. Molecular formula: C3H5O6P.3C6H13N. Mole weight: 465.56. | |
| Phosphonic acid, [(1S)-1-hydroxyethyl]-, dimethyl ester | Dimethyl ester of [(1S)-1-hydroxyethyl]-phosphonic acid is an intriguing derivative of phosphonic acid that has been analyzed extensively due to its potential as an anti-osteoporotic drug as well as its application as a chelating agent for heavy metal ions and a flame retardant for polymers. Its multifaceted usage makes it an attractive compound for further research and development. Alternative Names: [(S)-1-Hydroxyethyl]phosphonic acid dimethyl ester; Phosphonic acid, P-[(1S)-1-hydroxyethyl]-, dimethyl ester; Dimethyl [(1S)-1-hydroxyethyl]phosphonate; dimethyl (S)-(1-hydroxyethyl)phosphonate. Grades: 95%. CAS No. 106692-44-8. Molecular formula: C4H11O4P. Mole weight: 154.10. | |
| Phosphonic acid, (2-ethylhexyl)-, mono(2-ethylhexyl) ester | (2-Ethylhexyl) diphenyl phosphate, an esteemed biomedical commodity, boasts of its versatility in the medical industry as a plasticizing agent employed in medical apparatuses, notably PVC tubing and blood bags, while also exhibiting efficacy in ameliorating a myriad of neurological illnesses, particularly Alzheimer's disease, thanks to its calcium modulating properties within the brain. Alternative Names: 2-Ethylhexyl hydrogen-2-ethylhexylphosphonate; (2-Ethylhexyl)phosphonic Acid Mono-2-ethylhexyl Ester. Grades: Solid Content: 98±2 %. CAS No. 14802-03-0. Molecular formula: C16H35O3P. Mole weight: 306.42. | |
| Phosphonosuccinic acid | Phosphonosuccinic acid is a useful research chemical. Alternative Names: Butanedioic acid, 2-phosphono-. CAS No. 5768-48-9. Molecular formula: C4H7O7P. Mole weight: 198.07. | |
| Phosphoric acid 6,6'-di(9-anthryl)-1,1'-spirobiindan-7,7'-diyl ester | Phosphoric acid 6,6'-di(9-anthryl)-1,1'-spirobiindan-7,7'-diyl ester is a chiral phosphoric acid catalyst for a variety of enantioselective transformations, especially for carbon-carbon and carbon-heteroatom bond-forming reactions. Alternative Names: 3,7-Di(9-anthryl)-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-ol 5-oxide. Grades: 98%. CAS No. 1393527-23-5. Molecular formula: C45H31O4P. Mole weight: 666.70. | |
| PHTPP | PHTPP, a pyrazolo[1,5-α]pyrimidine-based ligand, is a selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. This compound has been used to selectively target ERβ in the study of the opposing effects of hormone therapy on tumors expressing either ER subtype. Alternative Names: 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol. Grades: ≥99% by HPLC. CAS No. 805239-56-9. Molecular formula: C20H11F6N3O. Mole weight: 423.31. | |
| (-)-Phyllocladene | (-)-Phyllocladene is extracted from the leaves essential oil of Callicarpa macrophylla. Alternative Names: Phyllocladene; 8beta,13beta-Kaur-16-ene; Sciadopitene; Dacrene; [8R,13S,(-)]-Kaura-16-ene. Grades: 97.0%. CAS No. 20070-61-5. Molecular formula: C20H32. Mole weight: 272.47. | |
| Phyperunolide E | Phyperunolide E is a steroid isolated from Physalis peruviana. Alternative Names: Phyperunolide E; 1198400-52-0; (1S,2R,5S,6S,7R,9R,11R,12R,15S,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-5,6,12,15-tetrahydroxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadecan-3-one; CHEMBL3797273; AKOS040762184; F94017. Grades: 98.0%. CAS No. 1198400-52-0. Molecular formula: C28H40O9. Mole weight: 520.619. | |
| Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-β-D-glucopyranoside is a natural product found in Cortinarius canarius, Saururus chinensis. It is a glycoside of Physcion, a natural anthraquinone derivative, and has an inhibitory effect on the infection process of Blumeria graminis on wheat. It has been used in research to treat glomerulonephritis. Uses: Relating to the treatment of the glomerulonephritis. Alternative Names: Physcion 8-O-glucoside; 1-(β-D-Glucopyranosyloxy)-8-hydroxy-3-methoxy-6-methyl-9,10-anthracenedione; Glucopyranoside, 8-hydroxy-3-methoxy-6-methyl-1-anthraquinonyl, β-D-; Anthraglycoside A; Physcion 8-O-β-D-glucoside; Physcion 8-β-D-glucopyranoside; Physcion-8-β-D-monoglucoside; Physcion 8-β-D-glucoside. Grades: >98%. CAS No. 23451-01-6. Molecular formula: C22H22O10. Mole weight: 446.40. | |
| Phytosterol Ester | Phytostanol and phytosterol esters are chemically stable materials, having comparable chemical and physical properties to edible fats and oils. Grades: 50%. | |
| Picfeltarraenin IB | Picfeltarraenin IB is a triterpenoid Picria isolated from felterrae Lour. Alternative Names: HY-N2211. Grades: 98%. CAS No. 97230-46-1. Molecular formula: C42H64O14. Mole weight: 792.95. | |
| Picoplatin | Picoplatin is a new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis. Alternative Names: AMD473; AMD 473; AMD-473; NX 473; NX473; NX-473; ZD0473; ZD 0473; ZD-0473. CAS No. 181630-15-9. Molecular formula: C6H10Cl2N2Pt. Mole weight: 376.15. | |
| Picrasidine S | Picrasidine S is an alkaloid isolated from the root bark of Picrasma quassioides. Uses: Antiulcer. Alternative Names: 1H-Indolo[2,3-a]quinolizin-5-ium, 4-(4,8-dimethoxy-9H-pyrido[3,4-b]indol-1-yl)-2,3,4,12-tetrahydro-7,11-dimethoxy-, (+/-)-; 9H-Pyrido[3,4-b]indole, 1H-indolo[2,3-a]quinolizin-5-ium deriv. Grades: 93%. CAS No. 112503-87-4. Molecular formula: C30H29N4O4. Mole weight: 509.6. | |
| Picroside III | Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS) that protects liver. Uses: Protecting liver. Alternative Names: [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(E)-3-(4-hydroxy-3-methoxyphenyl)propenoyloxy]-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside; Picroside III; (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl beta-D-glucopyranoside 6-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate]; [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(E)-3-(4-hydroxy-3-Methoxyphenyl)propenoyloxy]-1aβ-(hydroxyMethyl)oxireno[4,5]cy; AMphicoside ?. Grades: >98%. CAS No. 64461-95-6. Molecular formula: C25H30O13. Mole weight: 538.5. | |
| Pierreione B | Pierreione B isolated from Antheroporum pierrei. Alternative Names: 7-[4-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-3-methoxyphenyl]-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one. Grades: 0.98. CAS No. 1292766-21-2. Molecular formula: C26H28O7. Mole weight: 452.496. | |
| Pifithrin-α hydrobromide | Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. Alternative Names: Pifithrin-alpha; Pifithrin alpha; PFT-alpha; PFTalpha; PFT alpha. Grades: >98%. CAS No. 63208-82-2. Molecular formula: C16H18N2OS·HBr. Mole weight: 367.3. | |
| Pigment Yellow 185 | Pigment Yellow 185. CAS No. 76199-85-4. | |
| PIK 75 hydrochloride | PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM. Alternative Names: PIK 75 hydrochloride; PIK75 hydrochloride; PIK-75 hydrochloride. Grades: >98%. CAS No. 372196-77-5. Molecular formula: C16H14BrN5O4S.HCl. Mole weight: 488.74. | |
| Pilaralisib | Pilaralisib, also known as XL147, is a methylbenzenesulfonamide derivative that reversibly inhibits class I PI3Ks (IC50s = 39, 36, 23, and 383 nM for p110α, δ, γ, and β, respectively), with potential antineoplastic activity. Alternative Names: 2-amino-N-(3-(N-(3-((2-chloro-5-methoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-2-methylpropanamide.; XL147; XL 147; XL-147; SAR245408; SAR-245408; SAR 245408; Pilaralisib. CAS No. 934526-89-3. Molecular formula: C25H25ClN6O4S. Mole weight: 541.02. | |
| Pilaralisib analogue | Pilaralisib analogue. CAS No. 956958-53-5. | |
| Pilocarpine-[d3] hydrochloride | Pilocarpine-[d3] hydrochloride is a deuterated labelled form of Pilocarpine, which is used as a miotic in the treatment of glaucoma. Alternative Names: Pilocarpine-d3 HCl; Pilocarpine-d3 hydrochloride; Pilocarpine-[d3] HCl. Grades: > 95%. Molecular formula: C11H13N2O2D3·HCl. Mole weight: 247.74. | |
| Pimavanserin | Pimavanserin is a potent and selective 5-HT2A receptor inverse agonist used in the treatment of Parkinson's disease psychosis. Uses: Drug used in the treatment of parkinson's disease psychosis. Alternative Names: ACP-103; AC-5273; ACP 103; AC 5273; ACP103; AC5273;1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea. Grades: ≥95%. CAS No. 706779-91-1. Molecular formula: C25H34FN3O2. Mole weight: 427.55. | |
| Pimavanserin-[d4] | Pimavanserin-[d4], is the labelled analogue of Pimavanserin, which is an atypical antipsychotic. Alternative Names: Pimavanserin-d4; Pimavanserin d4. Molecular formula: C25H30D4FN3O2. Mole weight: 431.59. | |
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