BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside | Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a remarkable natural compound renowned in the biomedical research.Its perfect value lies in the fact that it has been effectively studied for a wide range of diseases with its powerful antioxidant, anti-inflammatory, anti-tumor and neuroprotective potential. Alternative Names: Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside; quercetin 3-O-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside; 4H-1-Benzopyran-4-one, 3-[(6-deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranoside; SCHEMBL5086742; CHEBI:66288; DTXSID601105661; HY-N7607; AKOS040763663; MS-30697; PD158845; CS-0134761; Q27134830; 3-(2-O-beta-d-glucopyranosyl-alpha-l-rhamnopyranosyloxy)-3',4',5,7-tetrahydroxyflavone; 3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; 3-[(6-Deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 143016-74-4. Molecular formula: C27H30O16. Mole weight: 610.5. |  |
| Quercetin 3-O-glucuronide | Miquelianin, also known as Quercetin 3-O-glucuronide, a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John's wort), is a metabolite of quercetin. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl β-D-glucopyranosiduronic acid; Miquelianin; Mikwelianin; Q3GA; Quercetin 3-glucuronide; Quercetin 3-O-β-D-glucopyranosiduronic acid; Quercetin 3-O-β-D-glucuronide; Quercetin 3-O-β-D-glucuronopyranoside; Quercetin 3-β-D-glucuronide; Quercetin 3-β-D-glucuronopyranoside; Quercetin 3-β-glucuronide; Quercetin-3-O-β-glucuronide; Quercituron; Querciturone. Grades: 96.5%. CAS No. 22688-79-5. Molecular formula: C21H18O13. Mole weight: 478.36. | |
| Quercetin 3-O-sophoroside | Quercetin-3-O-sophoroside is a flavonoid isolated from B. napus (rapeseed). It is the natural ligand of Bet v 1. Alternative Names: QUOSP; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-5,7-dihydroxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 18609-17-1. Molecular formula: C27H30O17. Mole weight: 626.5. | |
| Quercetin 3-Sambubioside | Quercetin 3-Sambubioside is a natural compound isolated from several plant such as Eucommia ulmoides, Corymbose Hedyotis Herb, lotus leaf. Alternative Names: Quercetin 3-O-Sambubioside; Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]. Grades: 98%. CAS No. 83048-35-5. Molecular formula: C26H28O16. Mole weight: 596.5. | |
| Quinfamide | Quinfamide is an anti-amebic agent used to treat tropical parasitic infections. Alternative Names: 2-Furancarboxylic Acid 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl Ester; 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydro-6-quinoline; Amenide; Amenox; Win 40014. Grades: > 95%. CAS No. 62265-68-3. Molecular formula: C16H13Cl2NO4. Mole weight: 354.19. | |
| quinidine gluconate | Quinidine gluconate is the gluconate salt form of quinidine, which has been used as an antiarrhythmic and antimalarial agent. Alternative Names: Duraquin; Gluquinate; Dura-tab. Grades: 95%. CAS No. 7054-25-3. Molecular formula: C20H24N2O2.C6H12O7. Mole weight: 520.57. | |
| Quinocetone-[d5] | Labelled Quinocetone. Quinoenone is a kind of quinoxaline drugs, which can promote growth and increase feed conversion rate, inhibit a variety of intestinal pathogenic bacteria, and can significantly reduce the incidence of diarrhea in livestock and poultry. It is not only suitable for pigs, poultry and aquatic products, but also suitable for disease prevention and growth promotion of young animals and young birds. Alternative Names: 1-(3-Methyl-1,4-dioxido-2-quinoxalinyl)-3-phenyl-2-propen-1-one-d5; 1-(3-Methyl-2-quinoxalinyl)-3-phenyl-N,N'-dioxide 2-Propen-1-one-d5. Molecular formula: C18H9D5N2O3. Mole weight: 311.35. | |
| Quinovic acid | Quinovic acid is a natural triterpenoid isolated from the herbs of Mitragyna rotundifolia. Quinovic acid glycosides purified fraction may prevent and/or treat cancers. Uses: Anti-cancer. Alternative Names: (1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6b,9,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a,6a-dicarboxylic acid. Grades: >96%. CAS No. 465-74-7. Molecular formula: C30H46O5. Mole weight: 486.7. | |
| Quinovic acid 3β-O-(3',4'-O-isopropylidene)-β-D-fucopyranoside | Quinovic acid 3β-O-(3',4'-O-isopropylidene)-β-D-fucopyranoside is a triterpenoid isolated from Mitragyna rotundifolia. Alternative Names: Quinovic acid 3-O-(3',4'-O-isopropylidene)-beta-D-fucopyranoside. CAS No. 182132-59-8. Molecular formula: C39H60O9. Mole weight: 672.89. | |
| Quizartinib | This active molecular also known as AC220 and AC010220, is developed as a new second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, ten fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Now Quizartinib is in Phase-III clinical trials in Acute myeloid leukaemia. Uses: Treatment of acute myeloid leukaemia(aml). Alternative Names: 1-(5-(tert-butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea; AC220; AC 220; AC-220; AC010220; AC-010220; AC 010220; AC010220; Quizartinib. Grades: 98%. CAS No. 950769-58-1. Molecular formula: C29H32N6O4S. Mole weight: 560.67. | |
| (R)-(+)-1,2-Epoxydecane | (R)-(+)-1,2-Epoxydecane. Alternative Names: (+)-1,2-Epoxydecane; (R)-2-octyloxirane; Oxirane, 2-octyl-, (2R)-. Grades: 95%. CAS No. 67210-36-0. Molecular formula: C10H20O. Mole weight: 156.27. | |
| (R)-1-[5-(2,2,2-Trifluoroethoxy)-2-pyridyl]ethylamine | (R)-1-[5-(2,2,2-Trifluoroethoxy)-2-pyridyl]ethylamine is a useful research chemical. Alternative Names: (1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethanamine. Grades: 95%. CAS No. 953780-33-1. Molecular formula: C9H11F3N2O. Mole weight: 220.19. | |
| (R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride | (R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Alternative Names: (αR)-α-Methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1-naphthalenemethanamine Hydrochloride; Cinacalcet Impurity 18. CAS No. 1229225-42-6. Molecular formula: C20H19ClF3N. Mole weight: 365.82. | |
| (R)-(+)-1-Phenyl-1-Cyclohexyl-mathanol | (R)-(+)-1-Phenyl-1-Cyclohexyl-mathanol (CAS# 3113-96-0 ) is a useful research chemical. Alternative Names: (R)-Cyclohexylphenylmethanol. CAS No. 3113-96-0. Molecular formula: C13H18O. Mole weight: 190.28. | |
| (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzamide | (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzamide is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Alternative Names: Alogliptin Impurity 14; Alogliptin Carbamoyl Impurity. CAS No. 1820685-30-0. Molecular formula: C18H23N5O3. Mole weight: 357.41. | |
| ((R)-2-Biphenyl-4-yl-1-formylethyl)carbamic Acid t-Butyl Ester | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. CAS No. 149709-58-0. Molecular formula: C20H23NO3. Mole weight: 325.408. | |
| (R)-2-Hydroxybutyric acid | (R)-2-Hydroxybutyric acid. Alternative Names: (R)-2-Hydroxybutanoic acid. CAS No. 20016-85-7. Molecular formula: C4H8O3. Mole weight: 104.11. | |
| (R)-2-[[(tert-Butyldimethylsilyl)oxy]diphenylmethyl]pyrrolidine | (R)-2-[[(tert-Butyldimethylsilyl)oxy]diphenylmethyl]pyrrolidine (CAS# 1236033-34-3 ) is a useful research chemical. Alternative Names: tert-butyl-[diphenyl-[(2R)-2-pyrrolidinyl]methoxy]-dimethylsilane; tert-butyl-[diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-dimethylsilane. Grades: ≥ 97 %. CAS No. 1236033-34-3. Molecular formula: C23H33NOSi. Mole weight: 367.60. | |
| (R)-3-amino-3-(5-bromo-1-((1S,4S)-4-ethoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol | (R)-3-amino-3-(5-bromo-1-((1S,4S)-4-ethoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol. | |
| (R)-3-carboxy-N,N-dimethyl-N-(methyl-[d3])-2-(stearoyloxy)propan-1-aminium,monochloride | Stearoyl-L-carnitine-d3 chloride is a labelled stearoyl-L-carnitine. It is intended for use as an internal standard for the quantification of stearoyl-L-carnitine by GC- or LC-MS. Alternative Names: L-Stearoylcarnitine-d3; Octadecanoyl-L-carnitine-d3; R-Stearoyl carnitine-d3. Grades: 97% (CP). CAS No. 2245711-27-5. Molecular formula: C25H47D3ClNO4. Mole weight: 467.14. | |
| R406 Benzenesulfonate | R406 is a potent Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Alternative Names: R406; R 406; R-406. Grades: >98%. CAS No. 841290-81-1. Molecular formula: C28H29FN6O8S. Mole weight: 628.63. | |
| (R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione | (R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is an intermediate of Exatecan, which is a DNA topoisomerase I inhibitor used to study cancer. Alternative Names: (R)-Exatecan Intermediate 1; (4R)-4-ethyl-4-hydroxy-1H,3H,4H,6H,7H,8H,10H-pyrano[3,4-f]indolizine-3,6,10-trione; (4R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione. Grades: ≥95%. CAS No. 110351-91-2. Molecular formula: C13H13NO5. Mole weight: 263.25. | |
| (R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Alternative Names: (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; (4R)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; SCHEMBL3576264; (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 165117-54-4. Molecular formula: C10H16N2O6S3. Mole weight: 356.44. | |
| (R)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid | (R)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid, a highly promising drug candidate, has been extensively analyzed due to its remarkable anti-inflammatory, anti-cancer and neuroprotective properties. In addition, its outstanding potency in counteracting diabetes and metabolic disorders has been revealed. Despite initial success, further exploration is warranted to completely grasp and harness its therapeutic potential. This entails in-depth investigation of its complex mechanisms of action, side-effect profile, and pharmacokinetics, among other factors, to consider its potential as a clinical agent. Alternative Names: 5-({3-(Heptyloxy)-5-[(2R)-2-octanyloxy]benzyl}oxy)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[3-(heptyloxy)-5-[[(1R)-1-methylheptyl]oxy]phenyl]methoxy]-. Grades: ≥95%. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| R 568 hydrochloride | R 568 is positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR), increasing the sensitivity to activation by extracellular Ca2+. It dose-dependently decreases circulating levels of PTH in both normal individuals and patients with primary hyperparathyroidism in clinical trials. R-568 is used in research to explore novel actions of CaSR. Alternative Names: R 568 hydrochloride; R568 hydrochloride; R-568 hydrochloride; 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride; 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine Hydrochloride (9CI); (R)-2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine Hydrochloride; KRN 568; NPS-R 568; Norcalcin; R 568; R 568 (Pharmaceutical); Tecalcet Hydrochloride. Grades: ≥99% by HPLC. CAS No. 177172-49-5. Molecular formula: C18H22ClNO.HCl. Mole weight: 340.29. | |
| R 59-022 | R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM) without affecting phosphodiesterase or phosphatidylinositol kinase, and potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. R 59-022 also blocks vascular contraction induced by the thromboxane analog U-46619. At 10 μM, R 59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. Uses: Enzyme inhibitors. Alternative Names: R59022; R-59022; R 59022; 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Diacylglycerol Kinase Inhibitor I. Grades: ≥98% by HPLC. CAS No. 93076-89-2. Molecular formula: C27H26FN3OS. Mole weight: 459.58. | |
| (R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one | (R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one is a metabolite of Levosimendan. Alternative Names: OR-1855; 3(2H)-Pyridazinone, 6-(4-aminophenyl)-4,5-dihydro-5-methyl-, (R)-. Grades: 98%. CAS No. 101328-85-2. Molecular formula: C11H13N3O. Mole weight: 203.24. | |
| R 7050 | R 7050 is an inhibitor of TNF-α receptor 1 signaling. Alternative Names: R-7050; R 7050; R7050; TNF-α Antagonist III; 8-chloro-4-phenylsulfanyl-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline; 12E-954; SMR000169297; AC1LSEB1; Bionet1_000448; MLS000543328; CHEMBL1440293; SCHEMBL12058463; CTK8G3499. CAS No. 303997-35-5. Molecular formula: C16H8ClF3N4S. Mole weight: 380.77. | |
| (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Alternative Names: 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione; Linagliptin Impurity C. Grades: ≥95%. CAS No. 1791405-13-4. Molecular formula: C15H20N6O2. Mole weight: 316.36. | |
| Rabeprazole Carboxylic Acid | Rabeprazole Carboxylic Acid. CAS No. 1163685-31-1. | |
| Rabeprazole N-Oxide | An impurity of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Alternative Names: 2-[[[4-(3-Methoxypropoxy)-3-methyl-1-oxido-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; 2-[[[1-Oxide-4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; Rabeprazole EP Impurity D. Grades: > 95%. CAS No. 924663-38-7. Molecular formula: C18H21N3O4S. Mole weight: 375.45. | |
| (Rac)-BL-918 | (Rac)-BL-918 is the racemate of BL-918, a potent UNC-51-like kinase 1 (ULK1) activator. Alternative Names: Benzeneacetamide, α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(2,4-difluorophenyl)-. Grades: ≥98%. CAS No. 2435589-07-2. Molecular formula: C23H15F8N3OS. Mole weight: 533.44. | |
| rac-cis-7-Hydroxy pramipexole | An impurity of Pramipexole, which is a thiazole derivative usually used as a D2-receptor agonist. Alternative Names: rac-cis-7-Hydroxy-Pramipexole; (6S,7S)-2-amino-6-(propylamino)-4,5,6,7-tetrahydrobenzo[d]thiazol-7-ol. Grades: 95%. CAS No. 1001648-71-0. Molecular formula: C10H17N3OS. Mole weight: 227.33. | |
| Rac-cis-Sertraline Hydrochloride | Rac-cis-Sertraline Hydrochloride is an extensively utilized pharmacological compound within the biomedical sector used in studying psychiatric afflictions, including depression, panic disorder and obsessive-compulsive disorder. Its mechanism of action entails selective inhibition of serotonin reuptake, thereby reestablishing homeostasis of this pivotal neurotransmitter within the cerebral research. Uses: Potent and selective inhibitors of serotonin uptake. Alternative Names: cis racemic Setraline; rac-cis-Sertraline Hydrochloride. CAS No. 79617-95-1. Molecular formula: C17H18Cl3N. | |
| racemic Tenofovir-[d7] | A labelled form of rac-Tenofovir. Tenofovir is an acyclic phosphonate nucleotide derivative used in antiviral treatment as an everse transcriptase inhibitor. Alternative Names: racemic Tenofovir-d7; rac-Tenofovir-d7; [(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy-d7]methyl]phosphonic Acid; (R)-9-(2-Phosphonomethoxypropyl)adenine-d7. Grades: 95% by HPLC; 98% atom D. Molecular formula: C9H7D7N5O4P. Mole weight: 294.26. | |
| rac-Monepantel-[d5] | rac-Monepantel-[d5] is the labelled analogue of rac-Monepantel, which is an impurity of Monepantel. Monepantel is a new anthelmintic agent used in the treatment of parasitic nematodes via stun or kill without damaging the host entity. Alternative Names: rac-Monepantel-d5; N-[1-Cyano-2-[5-cyano-2-(trifluoromethyl)phenoxy]-1-methylethyl]-4-[(trifluoromethyl)thio]benzamide-d5; racemic-Monepantel-d5. Grades: >95%. CAS No. 2747918-33-6. Molecular formula: C20H8D5F6N3O2S. Mole weight: 478.43. | |
| rac-N-Nitroso Mirabegron-[d5] | rac-N-Nitroso Mirabegron-[d5] is a labelled impurity of mirabegron, which is a medication used to treat overactive bladder. Alternative Names: 2-(2-aminothiazol-4-yl)-N-(4-(2-((2-hydroxy-2-(phenyl-d5)ethyl)(nitroso)amino)ethyl)phenyl)acetamide. Molecular formula: C21H18D5N5O3S. Mole weight: 430.54. | |
| Rac-Sitagliptin | Rac-Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Uses: Dipeptidyl-peptidase iv inhibitors. Alternative Names: Sitagliptin Raccemate; Sitagliptin impurity E; 7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; 4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine. Grades: >95%. CAS No. 823817-56-7. Molecular formula: C16H15F6N5O. Mole weight: 407.31. | |
| Radiprodil | Radiprodil is an orally active and selective NMDA NR2B antagonist as a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions, blocking pain signaling without interacting with other NMDA receptor subtypes thus potentially improving therapeutic index and side effect profile. Uses: Nmda nr2b antagonist. Alternative Names: RGH-896; RGH896; RGH 896; 2-(4-((4-Fluorophenyl)methyl)piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide. Grades: ≥98%. CAS No. 496054-87-6. Molecular formula: C21H20FN3O4. Mole weight: 397.41. | |
| Radotinib | Radotinib, also known as IY-5511, is an orally available, hydrochloride salt form of radotinib, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. The inhibitory effect of radotinib on these specific tyrosine kinases may decrease cellular proliferation and inhibit angiogenesis. This agent has shown potent efficacy in CML cells that are resistant to the first-generation standard tyrosine kinase inhibitors, such as imatinib, nilotinib and dasatinib. PDGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: IY-5511; IY 5511; IY5511; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyrazin-2-ylpyrimidin-2-yl)amino]benzamide. Grades: >98%. CAS No. 926037-48-1. Molecular formula: C27H21F3N8O. Mole weight: 530.515. | |
| Radotinib-[d6] | Radotinib-[d6] is deuterium labelled Radotinib. Radotinib, also known as IY-5511, is a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Alternative Names: 4-(Methyl-d3)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide-2,5,6-d3. CAS No. 2754051-83-5. Molecular formula: C27H15D6F3N8O. Mole weight: 536.55. | |
| Rafigrelide | Rafigrelide is a platelet aggregation inhibitor, which plays a central role in atherothrombotic events. It could prolonge clot formation time and reduce clot strength. Uses: Rafigrelide plays a central role in atherothrombotic events. Alternative Names: 6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one;6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2-one. Grades: >98 %. CAS No. 1029711-88-3. Molecular formula: C12H11Cl2N3O. Mole weight: 284.14. | |
| Raltegravir-[13C,d3] Potassium Salt | Raltegravir-[13C,d3] Potassium Salt. | |
| Raltitrexed | Raltitrexed is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. Raltitrexed is used as an antimetabolite drug used in the treatment of colorectal cancer, and may be beneficial for malignant mesothelioma treatment. Uses: The treatment of colorectal cancer. Alternative Names: Tomudex; ZD1694; ZD-1694; ICI-D1694; (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid. Grades: > 98%. CAS No. 112887-68-0. Molecular formula: C21H22N4O6S. Mole weight: 458.49. | |
| Ramatroban | Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. Alternative Names: Ramatroban; Bay u 3406; Bay u-3405; BAY u3405; EN 137774. Grades: >98%. CAS No. 116649-85-5. Molecular formula: C21H21FN2O4S. Mole weight: 416.47. | |
| Ramelteon | Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Alternative Names: (S)-N-[2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl]propionamide; TAK-375. Grades: >98%. CAS No. 196597-26-9. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| Ramelteon Impurity 7 HCl | Ramelteon Impurity 7 HCl is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Alternative Names: 2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine hydrochloride; Ramelteon Stage-2 Impurity HCl. Grades: >98%. CAS No. 1053239-39-6. Molecular formula: C13H17NO.HCl. Mole weight: 239.74. | |
| Ramelteon Impurity E | Ramelteon Impurity E is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Alternative Names: N-[2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetamide. CAS No. 196597-16-7. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Ramipril EP Impurity A | An impurity of Ramipril, an angiotensin-converting enzyme inhibitor used to treat hypertension and congestive heart failure. Alternative Names: Ramipril Methyl Ester; Ramipril Related Compound B. Grades: 95%. CAS No. 108313-11-7. Molecular formula: C22H30N2O5. Mole weight: 402.5. | |
| Ramosetron Impurity 12 | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Alternative Names: Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanone hydrochloride; pyrrolidin-1-yl(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone; hydrochloride; VIQQUDRWPRGFBZ-UHFFFAOYSA-N; SCHEMBL9051125; DTXSID60597128; FD7376; (4,5,6,7-TETRAHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)(PYRROLIDIN-1-YL)METHANONE HCL; FT-0709212; 5-pyrrolidinocarbonyl-4,5,6,7-tetrahydrobenzimidazole hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidine hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidinehydrochloride; Methanone, 1-pyrrolidinyl(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-, hydrochloride (1:1); Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanonehydrochloride; (Pyrrolidin-1-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)methanone--hydrogen chloride (1/1). Grades: > 95%. CAS No. 132036-42-1. Molecular formula: C12H17N3O. Mole weight: 219.29. | |
| Ranitidine EP Impurity J | Ranitidine EP Impurity J is an impurity of Ranitidine. Ranitidine is a medication that decreases stomach acid production. It can be used in treatment of peptic ulcer disease. Alternative Names: 1,1'-N-[Methylenebis(sulphanediylethylene)]bis(N'-methyl-2-nitroethene-1,1-diamine. Grades: > 95%. CAS No. 1331637-48-9. Molecular formula: C11H22N6O4S2. Mole weight: 366.46. | |
| Ranitidine Related Compound A | An impurity of Ramipril, an ACE inhibitor that can be used to treat hypertension. Alternative Names: 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine fumarate. CAS No. 91224-69-0. Molecular formula: C14H22N2O5S. Mole weight: 330.40. | |
| Rankinidine | Rankinidine is found in Gelsmium elegans. Alternative Names: Humantenine, 4-demethyl-. Grades: > 95%. CAS No. 106466-66-4. Molecular formula: C20H24N2O3. Mole weight: 340.42. | |
| Rasagiline mesylate | Rasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Uses: Neuroprotective agents. Alternative Names: TVP-1012; TVP 1012; TVP1012. Grades: >98%. CAS No. 161735-79-1. Molecular formula: C12H13N.CH4O3S. Mole weight: 267.34. | |
| Rauvotetraphylline B | Rauvotetraphylline B is an alkaloid isolated from Rauvotetraphyllum. Alternative Names: Rauvotetraphylline B; 1422506-50-0; (2S,3R,4S,5S,6R)-2-[[(1S,12S,14S,15E,16R)-13-(4,6-dimethylpyridin-2-yl)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraen-16-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Grades: >97%. CAS No. 1422506-50-0. Molecular formula: C31H37N3O6. Mole weight: 547.65. | |
| Rauvovertine A | Rauvovertine A is an alkaloid isolated from the stems of Rauvolfia verticillata and exhibits anti-tumor activity. Alternative Names: 17-epi-Rauvovertine A. Grades: 96.5%. CAS No. 2055073-75-9. Molecular formula: C19H22N2O3. Mole weight: 326.396. | |
| RBC8 | RBC8 is a novel small molecule inhibitor of Ral GTPase; has IC50 of 3.5 μM in H2122 cell and 3.4 μM in H358 cell. Alternative Names: RBC8; RBC-8; RBC 8. Grades: >98%. CAS No. 361185-42-4. Molecular formula: C25H20N4O3. Mole weight: 424.45. | |
| (R)-Bicalutamide-[d4] | (R)-Bicalutamide-[d4] is the labelled (R)-enantiomer of Bicalutamide. Bicalutamide is an antiandrogen drug commonly used for the treatment of prostate cancer. Alternative Names: (R)-Bicalutamide D4; (2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-d4)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex-d4. Grades: >95%. CAS No. 1217826-87-3. Molecular formula: C18H10D4F4N2O4S. Mole weight: 434.41. | |
| (R)-Cetirizine-[d4] Dihydrochloride | (R)-Cetirizine-[d4] Dihydrochloride is the labelled salt of Levocetirizine, which is a histamine H1 receptor antagonist and could be used as an antihystaminic agent. Alternative Names: Levocetirizine D4 Dihydrochloride; 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride; (-)-Cetirizine-d4 Dihydrochloride. Grades: 98% by CP; 98% atom D. Molecular formula: C21H23D4Cl3N2O3. Mole weight: 465.83. | |
| (R)-Cinacalcet-[d3] | (R)-Cinacalcet-D3 is a labelled analogue of Cinacalcet. Cinacalcet is a calcimimetic activating the calcium-sensing receptor. It is indicated for the treatment of secondary hyperparathyroidism and hypercalcemia in patients with parathyroid gland cancer. Alternative Names: (R)-Cinacalcet D3. Grades: 98% by HPLC; 99% atom D. CAS No. 1228567-12-1. Molecular formula: C22H19D3F3N. Mole weight: 360.43. | |
| (R)-Cinacalcet-[d3] Hydrochloride | (R)-Cinacalcet-[d3] Hydrochloride is the labelled salt of (R)-Cinacalcet. Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Alternative Names: (R)-Cinacalcet-D3 Hydrochloride; (R)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine-d3 Hydrochloride; Mimpara-d3; Sensipar-d3; Cinacalcet-d3 Hydrochloride. Grades: ≥98% by HPLC; 99% atom D. Molecular formula: C22H20D3ClF3N. Mole weight: 396.89. | |
| (R)-Citalopram-[d4] Oxalate | (R)-Citalopram-[d4] Oxalate is the labelled analogue of (R)-Citalopram Oxalate. (R)-Citalopram Oxalate is an inhibitor of serotonin (5-HT) uptake. It shows antidepressant activity. Alternative Names: (-)-(R)-Citalopram-d4 Oxalate; (R)-Citalopram Oxalate-d4; 1-(3-Dimethylaminopropyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile-d4 Oxalate; Escitalopram EP Impurity K-d4. Grades: 98% by HPLC. Molecular formula: C20H17D4FN2O.C2H2O4. Mole weight: 418.45. | |
| (R)-Crizotinib-[d5] (piperidine-[3,3,4,5,5-d5]) | One of the isotopic labelled form of (R)-Crizotinib, which is probably be a potent ALK inhibitor as well as c-MET inhibitor. Alternative Names: (R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-ylamine. Grades: 95% by HPLC; 98% atom D. CAS No. 1395950-84-1. Molecular formula: C21H17D5Cl2FN5O. Mole weight: 455.37. | |
| (R)-Darifenacin-[d4] Hydrobromide | (R)-Darifenacin-[d4] Hydrobromide is the labelled salt of (R)-Darifenacin, which is the enantiomeric impurity of Darifenacin, a medication used to treat urinary incontinence. Alternative Names: (R)-Darifenacin-d4 Hydrobromide; (3R)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α-α-diphenyl-3-pyrrolidineacetamide-d4 Hydrobromide; ent-Darifenacin-d4 Hydrobromide. Grades: >95%. CAS No. 1261394-25-5. Molecular formula: C28H27D4BrN2O2. Mole weight: 511.49. | |
| Rebamipide | Rebamipide has been shown to enhance mucosal defense by scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. Uses: Enzyme inhibitors. Alternative Names: Proamipide; Mucosta; OPC-12759; 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid; 2-(4-chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid; NSC-758955; 2-[(4-chlorobenzoyl)amino]-3-(2-hydroxyquinolin-4-yl)propanoic acid. Grades: >98%. CAS No. 90098-04-7. Molecular formula: C19H15ClN2O4. Mole weight: 370.79. | |
| Rebamipide impurity 1 | An impurity of Rebamipide. Rebamipide is an amino acid derivative of 2-(1H)-quinolinone. It can be used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. Alternative Names: 4-Chloro-N-(2-(2-oxo-1,2-dihydroquinolin-4-yl)ethyl)benzamide; 4-Chloro-N-[2-(1,2-dihydro-2-oxo-4-quinolinyl)ethyl]benzamide. Grades: 95%. CAS No. 100342-53-8. Molecular formula: C18H15ClN2O2. Mole weight: 326.79. | |
| Rebamipide impurity 2 | An impurity of Rebamipide. Rebamipide is an amino acid derivative of 2-(1H)-quinolinone. It can be used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. Grades: > 95%. CAS No. 94670-39-0. Molecular formula: C8H6ClNO2. Mole weight: 183.59. | |
| Rebastinib | Rebastinib is an orally bioactive inhibitor of Bcr-Abl that binds to and inhibits Bcr-Abl fusion oncoprotein. Rebastinib changes the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation. It also exhibits inhibitory activity at SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2. Uses: Antineoplastic agents. Alternative Names: DCC2036; DCC-2036; DCC 2036; Rebastinib. 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide. Grades: ≥98%. CAS No. 1020172-07-9. Molecular formula: C30H28FN7O3. Mole weight: 553.598. | |
| Rebeprazole sulfone N-oxide | An impurity of Rabeprazole. Rabeprazole is a proton pump inhibitor as an antiulcer drug. Alternative Names: 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-1-oxido-2-pyridinyl]methyl]sulfonyl]-. Grades: 95%. CAS No. 924663-37-6. Molecular formula: C18H21N3O5S. Mole weight: 391.44. | |
| Rediocide A | Rediocide A is extracted from the herbs of Trigonostemon reidioides (Kurz) Craib. It can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah and induce GPCR internalization and desensitization, which are mediated by the activation of conventional protein kinase C. It displays potent activity against fleas (Ctenocephalides felis) in an artificial membrane feeding system with LD(90) values ranging from 0.25 to 0.5 ppm. It is used as an insecticide. Alternative Names: Butanoic acid, 3-methyl-, (2S,4S,4aS,5R,7R,10S,11R,12Z,14E,17aS,18S,20R,20aS,21S,21aR,22aS,23S,23aR,24R,26S,27R)-4,4a,5,6,7,8,9,10,11,16,17a,18,19,20,20a,21,21a,22a,23,23a-eicosahydro-4a,5,20a,21-tetrahydroxy-21a-(hydroxymethyl)-5,18,26,27-tetramethyl-16-oxo-2-phenyl-4,24-methanolo-2,20,23-(epoxymethe. Grades: 97.0%. CAS No. 280565-85-7. Molecular formula: C44H58O13. Mole weight: 794.92. | |
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