BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Roemerine | Roemerine is found in the leaves of Nelumbo nucifera, which has some anti-prostate cancer effect and alleviates adverse reactions in paclitaxel combination administration. Alternative Names: Remerine; Aporheine. Grades: > 95%. CAS No. 548-08-3. Molecular formula: C18H17NO2. Mole weight: 279.33. |  |
| (R)-Ofloxacin | An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Alternative Names: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; (+)-Ofloxacin. Grades: > 95%. CAS No. 100986-86-5. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| Rolapitant | Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Alternative Names: (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| (R)-Omeprazole Sodium Salt | (R)-Omeprazole Sodium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: R-form of omeprazole. gastric proton-pump inhibitor. Alternative Names: 5-Methoxy-2-[(R-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole sodium salt; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole sodium salt; (+)-Omeprazole sodium salt. Grades: >95%. CAS No. 161796-77-6. Molecular formula: C17H18N3NaO3S. Mole weight: 367.40. | |
| Rosarin | Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. It exhibits anti-inflammatory and neuroprotective effects. Alternative Names: (2E)-3-Phenylprop-2-en-1-yl 6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 84954-93-8. Molecular formula: C20H28O10. Mole weight: 428.4. | |
| Rosavin | Rosavin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. It exhibits antidepressant and anxiolytic activity. Uses: Antidepressant and anxiolytic. Alternative Names: [(E)-3-Phenyl-2-propenyl]6-O-(α-L-arabinopyranosyl)-β-D-glucopyranoside; [(E)-3-Phenyl-2-propenyl]6-O-α-L-arabinopyranosyl-β-D-glucopyranoside; (2E)-3-phenyl-2-propenyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside; (2S,3R,4S,5S,6R)-2-[(E)-3-phenylprop-2-enoxy]-6-([(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyMethyl)oxane-3,4,5-triole; Rosavidin; (2R,3R,4S,5S,6R)-2-(cinnamyloxy)-6-((((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)Methyl)tetrahydro-2H-pyran-3,4,5-triol; b-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-O-a-L-arabinopyranosyl-. Grades: >98%. CAS No. 84954-92-7. Molecular formula: C20H28O10. Mole weight: 428.43. | |
| Rosin X | Rosin X is a natural product found in Piper retrofractum and Rhodiola rosea. It has anti-inflammatory properties and antidepressant activity. Alternative Names: β-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl; (2E)-3-Phenyl-2-propen-1-yl β-D-glucopyranoside; β-D-Glucopyranoside, (2E)-3-phenyl-2-propenyl; β-D-Glucopyranoside, 3-phenyl-2-propenyl, (E)-; Chinese Rosin W; Rosin; Rosin (glycoside); trans-Cinnamyl β-D-glucopyranoside. Grades: >98%. CAS No. 85026-55-7. Molecular formula: C15H20O6. Mole weight: 296.32. | |
| Rostafuroxin | Rostafuroxin is a Na+/K+ ATPase modulator that treats hypertension by normalizing renal Na+/K+ ATPase pump function. Alternative Names: PST-2238; PST 2238; (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol. Grades: 98.07%. CAS No. 156722-18-8. Molecular formula: C23H34O4. Mole weight: 374.521. | |
| Rosthornin A | Rosthornin A, also called (5β,8α,9β,10α,11β,13α)-13,18-Dihydroxy-15-oxokaur-16-en-11-yl ace tate, is a natural diterpenoid found in the herbs of Rabdosia rosthornii. Alternative Names: (5β,8α,9β,10α,11β,13α)-13,18-Dihydroxy-15-oxokaur-16-en-11-yl ace tate. Grades: >95%. CAS No. 125164-55-8. Molecular formula: C22H32O5. Mole weight: 376.5. | |
| Rosthornin B | Rosthornin B, also called (5β,7α,8α,9β,10α,11β,13α)-7,13-Dihydroxy-15-oxokaur-16-ene-11,18- diyl diacetate, is a natural diterpenoid found in the herbs of Rabdosia rosthornii. Alternative Names: (5β,7α,8α,9β,10α,11β,13α)-7,13-Dihydroxy-15-oxokaur-16-ene-11,18- diyl diacetate. Grades: >95%. CAS No. 125181-21-7. Molecular formula: C24H34O7. Mole weight: 434.5. | |
| Rosuvastatin EP Impurity C Sodium Salt | Rosuvastatin EP Impurity C Sodium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: Rosuvastatin Impurity Sodium Salt; 5-Oxo Rosuvastatin Sodium Salt; Sodium (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate; (3R,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic Acid Sodium Salt; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, sodium salt (1:1), (3R,6E)-; (3R,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic acid sodium salt. Grades: ≥95%. CAS No. 1620823-61-1. Molecular formula: C22H25FN3NaO6S. Mole weight: 501.51. | |
| Rosuvastatin EP Impurity N Calcium Salt | Rosuvastatin EP Impurity N Calcium Salt. | |
| Rosuvastatin Impurity 12 | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Alternative Names: SCHEMBL1021914; SCHEMBL1022804; 2-((4R,6S)-6-((E)-2-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid; 894787-93-0. Grades: 95%. CAS No. 894787-93-0. Molecular formula: C25H32FN3O6S. Mole weight: 521.60. | |
| Rotigotine Hydrochloride | The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50: 13 nM and 0.71 nM for D2 and D3 receptor respectively. Uses: The hydrochloride salt form of rotigotine which is a dopamine d2 and d3 receptor agonist and has been shown to be effective in the treatment of parkinson's disease. Alternative Names: Rotigotine hydrochloride; Rotigotine HCl; Rotigotine (Hydrochloride); (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: >99 %. CAS No. 125572-93-2. Molecular formula: C19H26ClNOS. Mole weight: 351.93. | |
| Roxithromycin EP Impurity G | Roxithromycin EP Impurity G. CAS No. 425365-64-6. | |
| (R)-Oxybutynin-[d11] | A labelled impurity of Oxybutynin which belongs to a class of drugs called anticholinergics / antimuscarinics. Alternative Names: 4-(Diethylamino)but-2-yn-1-yl (R)-2-(cyclohexyl-d11)-2-hydroxy-2-phenylacetate; (R)-Oxybutynin D11; Benzeneacetic acid, α-cyclohexyl-d11-α-hydroxy-, 4-(diethylamino)-2-butynyl ester, (αR)-; (-)-Oxybutynin-d11; (R)-Oxybutynin-d11; Aroxybutynin-d11. Grades: >95%. Molecular formula: C22H20NO3D11. Mole weight: 368.56. | |
| RP-6685 | RP-6685. CAS No. 2832047-80-8. | |
| (R)-(-)-Phenylephrine-[d3] Hydrochloride | (R)-(-)-Phenylephrine-[d3] Hydrochloride is the labelled salt of Phenylephrine, which is a selective α1-adrenergic receptor agonist of the phenethylamine class. Alternative Names: (R)-(-)-Phenylephrine D3 Hydrochloride; (R)-(-)-Phenylephrine-2,4,6-d3 HCl; Phenylephrine D3 hydrochloride; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl](2,4,6-D3)phenol hydrchloride; (αR)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol-d3 Hydrochloride; (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl Alcohol-d3 Hydrochloride. Grades: >95%. CAS No. 1276197-50-2. Molecular formula: C9H11D3ClNO2. Mole weight: 206.68. | |
| (R)-Praziquantel-[d11] | (R)-Praziquantel-[d11] is the labelled analogue of (R)-Praziquantel, which is the active enantiomer of Praziquantel. Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Alternative Names: (R)-Praziquantel-d11; (11bR)-2-(Cyclohexyl-1,2,2,3,3,4,4,5,5,6,6-d11-carbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one. Grades: 98% by HPLC. CAS No. 1399880-38-6. Molecular formula: C19H13D11N2O2. Mole weight: 323.48. | |
| (R,R)-Empagliflozin Impurity | (R,R)-Empagliflozin Impurity is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: (R,R)-Empagliflozin. Grades: 95%. CAS No. 2452301-42-5. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| (R,R)-Palonosetron HCl | An impurity of Palonosetron which is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting. Alternative Names: Palonosetron (R,R)-Isomer (HCl Salt); (3aR)-2-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one HCl. Grades: > 95%. CAS No. 135729-75-8. Molecular formula: C19H24N2O.HCl. Mole weight: 332.86. | |
| RRX-001 | RRX-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy. Alternative Names: RRX001; RRX 001; RRx-001; ABDNAZ. CAS No. 925206-65-1. Molecular formula: C5H6BrN3O5. Mole weight: 268.02. | |
| (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[13C6] | (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[13C6]. Uses: An amino alcohol metabolite of nicotine, and precursor to nnk. Alternative Names: 1-Methyl-3-(3'-pyridylcarbonyl-1,2',3',4',5',6'-13C6-pyrrolidinone. Grades: 95% atom 13C. CAS No. 1189492-36-1. Molecular formula: C5[13C]6H12N2O2. Mole weight: 210.18. | |
| (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[d3] | (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[d3]. Alternative Names: (+/-)-1-Methyl-3-(3-pyridinylcarbonyl)-2-pyrrolidinone-d3. CAS No. 86270-95-3. Molecular formula: C11H9D3N2O2. Mole weight: 207.24. | |
| (R,S)-1-Tosyl Glycerol-[d5] | (R,S)-1-Tosyl Glycerol-[d5]. Uses: Protected, labelled glycerol. Alternative Names: 1-Tosyloxy-2,3-propanediol-d5; 2,3-Dihydroxypropyl Tosylate-d5; p-Toluenesulfonic Acid Glyceryl Ester-d5; 1-p-Toluenesulfonate Glycerol-d5; 1,2,3-Propanetriol 1-(4-Methylbenzenesulfonate)-d5. CAS No. 928623-32-9. Molecular formula: C10H9D5O5S. Mole weight: 251.31. | |
| RS 504393 | RS 504393 is a highly selective CCR2 antagonist. Alternative Names: RS504393; RS 504393; RS-504393; 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one. CAS No. 300816-15-3. Molecular formula: C25H27N3O3. Mole weight: 417.5. | |
| (R)-Safinamide | (R)-Safinamide. CAS No. 174756-44-6. | |
| (R,S)-Ethambutol | An isomer of Ethambutol. Ethambutol is a medication primarily used to treat tuberculosis. Alternative Names: Ethambutol EP Impurity B; Ethambutol, meso-; Meso-ethambutol; Ethambutol, (R,S)-; rel-(R,S)-Ethambutol; Meso-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine; (2R,2'S)-2,2'-(Ethylenediimino)dibutan-1-ol; Ethambutol Related Compound A (USP). Grades: 95%. CAS No. 10054-06-5. Molecular formula: C10H24N2O2. Mole weight: 204.31. | |
| (R,S)-Metalaxyl Metabolite CGA 226048 | (R,S)-Metalaxyl Metabolite CGA 226048 is a metabolite of Metalaxyl. Metalaxyl is an acylalanine fungicide. Alternative Names: (R)-2-[(2,6-Dimethyl-phenyl)-2-methoxyacetyl amino] propionic acid-(S)-1-methoxycarbonyl ethyl ester. Molecular formula: C18H25NO6. Mole weight: 351.40. | |
| (R)-SN-38 | R-Enantiomer of SN-38. Used for making the bioconjugates and bifunctional isocyanate cross linking reagents. Alternative Names: (R)-7-Ethyl-10-Hydroxy Camptothecin; (4R)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (R)-4,11-diethyl-4,9-dihydroxy-1H-benzo[f]pyrano[4',3':4,5]pyrido[2,1-a]isoindole-3,14(4H,12H)-dione. Grades: 95%. CAS No. 647852-82-2. Molecular formula: C22H20N2O5. Mole weight: 392.41. | |
| (R,S)-Norcotinine-pyridyl-[d4] | (R,S)-Norcotinine-pyridyl-[d4] is the labelled metabolite of (+/-)-Cotinine. Alternative Names: 5-(3-Pyridinyl)-2-pyrrolidinone-pyridyl-d4; (RS)-Norcotinine-d4; (+/-)-Demethylcotinine-d4; (+/-)-Norcotinine-d4. Grades: 95%. CAS No. 1020719-70-3. Molecular formula: C9H6D4N2O. Mole weight: 166.21. | |
| (R,S)-Palonosetron HCl | An impurity of Palonosetron which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Antiemetics. Alternative Names: Palonosetron (R,S)-Isomer (HCl Salt); (3aR)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one HCl. Grades: > 95%. CAS No. 135755-51-0. Molecular formula: C19H24N2O.HCl. Mole weight: 332.86. | |
| (RS)-Sakuranetin | (RS)-Sakuranetin. Alternative Names: 4',5-Dihydroxy-7-methoxyflavanone; 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one. Grades: 95%. CAS No. 520-29-6. Molecular formula: C16H14O5. Mole weight: 286.283. | |
| (R)-(+)-Styrene-[d5] Oxide | (R)-(+)-Styrene-[d5] Oxide. Uses: A labelled main metabolite of styrene (s687790), catalyzed by epoxide hydrolase. Alternative Names: (R)-Phenyl-d5-oxirane; (2R)-2-(Phenyl-d5)-oxirane; (R)-(+)-(Epoxyethyl)benzene-d5; (2R)-2-(Phenyl-d5)oxirane; (R)-Epoxystyrene-d5; (R)-Phenylethylene-d5 Oxide. CAS No. 192506-02-8. Molecular formula: C8H3D5O. Mole weight: 125.18. | |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Alternative Names: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. | |
| (R)-(-)-Tamsulosin-[d5] Hydrochloride | One of the isotopic labelled form of (R)-(-)-Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Alternative Names: 5-[(2R)-2-[[2-(-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide-d5 Hydrochloride; Flomax-d5; Harnal-d5; Omnic-d5; Pradif-d5; YM 12617-1-d5; YM 617-d5; Yutanal-d5; (R)-(-)-Tamsulosin D5 Hydrochloride. Grades: >98%. Molecular formula: C20H24D5ClN2O5S. Mole weight: 450. | |
| (R)-Terazosin | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Alternative Names: (R)-Terazosin; 109351-34-0; [4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)piperazin-1-Yl][(2r)-Tetrahydrofuran-2-Yl]methanone[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(2R)-oxolan-2-yl]methanone; (R)-(4-(4-AMINO-6,7-DIMETHOXYQUINAZOLIN-2-YL)PIPERAZIN-1-YL)(TETRAHYDROFURAN-2-YL)METHANONE. Grades: 95%. CAS No. 109351-34-0. Molecular formula: C19H25N5O4. Mole weight: 387.43. | |
| RU 58841 | RU 58841 is a new non-steroidal antiandrogen which has potential for use in treating androgen-dependent skin disorders such as acne, hirsutism and androgen-dependent alopecia. Alternative Names: RU-58841; RU58841; RU 58841; 4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile. CAS No. 154992-24-2. Molecular formula: C17H18F3N3O3. Mole weight: 369.34. | |
| RU-59063 | RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM). Alternative Names: RU 59063; 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile. CAS No. 155180-53-3. Molecular formula: C17H18F3N3O2S. Mole weight: 385.4. | |
| Rubanthrone A | Rubanthrone A belongs to a kind of anthrones and is extracted from the aerial parts of Rubus ulmifolius Schott. It has moderate cytotoxicity against MCF-7 cell line. Grades: 98.0%. CAS No. 441764-20-1. Molecular formula: C17H14O10. Mole weight: 378.29. | |
| Rubiadin | Rubiadin is isolated from the roots of Rubia cordifolia. It acts as an antibacterial, antioxidant, and hepatoprotective agent. Uses: Antioxidant effect; hepatoprotective effect. Alternative Names: 9,10-Anthracenedione, 1,3-dihydroxy-2-methyl-. Grades: 99%. CAS No. 117-02-2. Molecular formula: C15H10O4. Mole weight: 254.2. | |
| Rubitecan | Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells. This agent also prevents repair of reversible single-strand DNA breaks. Alternative Names: RFS 2000; 9-Nitrocamptothecin; (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizinol[1,2-b]quinoline-3,14(4H,12H)-dione; 9-NC; Orathecin; 9-nitro-20(S)-camptothecin; Camptogen; (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 9-nitro-CPT; Nitrocamptothecin. Grades: ≥98%. CAS No. 91421-42-0. Molecular formula: C20H15N3O6. Mole weight: 393.35. | |
| Ruboxistaurin HCl | Ruboxistaurin, also called as LY 333531, initially developed for the treatment of diabetic retinopathy, inhibits isolated enzymes PKCβI and PKCβII with a half-maximal inhibitory constant of 4.5 and 5.9 nM, respectively. The half-life of ruboxistaurin, which can be orally administered, is approximately 9h and that of its metabolite 16h, therefore allowing once-daily dosing. Based on data from clinicalTrials.gov, Children's Hospital Medical Center, Cincinnati plan a phase I/II trial of the effect of ruboxistaurin for its safety, tolerability, and effectiveness in treating adult patients with heart failure on June 9, 2016. Uses: Enzyme inhibitors. Alternative Names: Ruboxistaurin Hydrochloride; LY-333531 hydrochloride; Ruboxistaurin (hydrochloride); 169939-93-9; LY 333531 hydrochloride; LY333531 hydrochloride; Ruboxistaurin-d6 Hydrochloride; 169939-94-0 (base). Grades: > 95%. CAS No. 169939-93-9. Molecular formula: C28H28N4O3.HCl. Mole weight: 505.01. | |
| Rubuminatus B | Rubuminatus B is a natural compound used in the research of rheumatoid arthritand other autoimmune disorders. It targets specific inflammatory pathways, inhibiting the overactive immune response. Alternative Names: 1β-Hydroxyrubuminatus A. Grades: 97.5%. CAS No. 1772614-25-1. Molecular formula: C29H44O5. Mole weight: 472.665. | |
| Ruscogenin | Ruscogenin is a saponin found in the root of Ophiopogon japonicus. It inhibits the expressions of TF, iNOS, and NF-kappaB p65 and is therefore a potential target for acute lung injury or sepsis. It remarkably inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. Alternative Names: (25R)-spirost-5-ene-1-beta,3-beta-diol; Ruscorectal; (1β,3β,25R)-Spirost-5-ene-1,3-diol. Grades: >98%. CAS No. 472-11-7. Molecular formula: C27H42O4. Mole weight: 430.6. | |
| Rutaevin | Rutaevin is a natural compound isolated from the root barks of Dictamnus dasycarpus. Alternative Names: Rutaevine. Grades: 97.5%. CAS No. 33237-37-5. Molecular formula: C26H30O9. Mole weight: 486.517. | |
| (R)-(-)-VAPOL hydrogenphosphate | (R)-(-)-VAPOL hydrogenphosphate is a chiral phosphoric acid catalyst for a variety of enantioselective transformations, especially for carbon-carbon and carbon-heteroatom bond-forming reactions. Alternative Names: (S)-VAPOL hydrogenphosphate; (8aR)-18-Hydroxy-8,9-diphenyldiphenanthro[4,3-d:3',4'-f][1,3,2]dioxaphosphepine 18-oxide. Grades: 95%. CAS No. 871130-18-6. Molecular formula: C40H25O4P. Mole weight: 600.60. | |
| (R)-Viloxazine-[d5] Hydrochloride | (R)-Viloxazine-[d5] Hydrochloride is the labelled (R)-isomer of Viloxazine which is used as an antidepressant. Uses: The labelled (r)-isomer of. Alternative Names: (R)-2-[((2-Ethoxy-d5)phenoxy)methyl]morpholine Hydrochloride; (R)-2-[(2-Ethoxy-d5)phenoxymethyl]tetrahydro-1,4-oxazine Hydrochloride. Grades: 95%. CAS No. 1246815-04-2. Molecular formula: C13H15D5ClNO3. Mole weight: 278.79. | |
| (R)-Viloxazine Hydrochloride | The R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) used as an antidepressant. Uses: The (r)-isomer of. Alternative Names: Morpholine, 2-[(2-ethoxyphenoxy)methyl]-, hydrochloride, (R)-. CAS No. 56287-63-9. Molecular formula: C13H20ClNO3. Mole weight: 273.76. | |
| (S)-1,1'-Binaphthyl-2,2'-disulfonimide | (S)-1,1'-Binaphthyl-2,2'-disulfonimide. Alternative Names: (11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide; 2,2'-(Iminobissulfonyl)-1,1'-binaphthalene; Dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine, 3,3,5,5-tetraoxide, (11bS)-. Grades: ≥95%. CAS No. 1245748-66-6. Molecular formula: C20H13NO4S2. Mole weight: 395.45. | |
| (S)-1-Octen-3-ol | (S)-1-Octen-3-ol. CAS No. 24587-53-9. | |
| S1RA | The sigma-1 (σ1) receptor is an intracellular, non-opioid receptor that is abundantly expressed in the central nervous system as well as peripherally. S1RA is a potent, selective antagonist of σ1 receptors (Ki = 17 nM) that weakly binds σ2 receptors (Ki = 9,300 nM). Alternative Names: E-52862; E52862; E 52862; 4-(2-((5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine. Grades: 98%. CAS No. 878141-96-9. Molecular formula: C20H23N3O2. Mole weight: 337.42. | |
| (S)-2,4-Dichloro-a-methyl-benzenemethanamine | (S)-2,4-Dichloro-a-methyl-benzenemethanamine. Alternative Names: (S)-1-(2,4-Dichlorophenyl)ethanamine; Benzenemethanamine, 2,4-dichloro-α-methyl-, (αS)-; (1S)-1-(2,4-dichlorophenyl)ethan-1-amine. Grades: 95%. CAS No. 133492-69-0. Molecular formula: C8H9Cl2N. Mole weight: 190.07. | |
| (S)-2-(benzo[d]thiazol-2-ylamino)-2-phenylethanol | (S)-2-(benzo[d]thiazol-2-ylamino)-2-phenylethanol. CAS No. 1235891-51-6. | |
| (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate | (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate, an active pharmaceutical intermediate, is a vital component in the pharmaceutical industry for synthesizing medications that alleviate pain and inflammation. Such disorders include osteoarthritis and arthritis, among others. Its significant role in medicinal chemistry, as a proficient synthesis intermediate, cannot be emphasized enough. Alternative Names: (+)-2-METHYLBUTYL-P[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; ACTIVE-AMYL P-ANISALAMINOCINNAMATE; ACT-AMYL P-ANISALAMINOCINNAMATE; (S)-(+)-2-METHYLBUTYL P-[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; (+)-2-methylbutyl-4-methoxybenzilidine-4'-aminocinnamate; (+)-2-met. Grades: 95%. CAS No. 24140-30-5. Molecular formula: C22H25NO3. Mole weight: 351.44. | |
| (S)-2-Methyl-[d3]-butanoyl Chloride | (S)-2-Methyl-[d3]-butanoyl Chloride. Alternative Names: (S)-2-Methyl-d3-butyryl Chloride; (S)-2-Methyl-d3-butanoic Acid Chloride; (S)-2-Methylbutyric acid chloride-d3. Grades: 95%. CAS No. 1217722-29-6. Molecular formula: C5H6D3ClO. Mole weight: 123.59. | |
| (S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- | (S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-. Alternative Names: (5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone; (S)-6-(4-aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone; Levosimendan Impurity 17. Grades: 95%. CAS No. 101328-84-1. Molecular formula: C11H13N3O. Mole weight: 203.24. | |
| S38093 HCl | S38093 HCl is a histamine H3 antagonist / inverse agonist. Alternative Names: S38093 Hydrochloride; S 38093 Hydrochloride; S-38093 Hydrochloride; S-38093 HCl; S 38093 HCl; S38093 HCl; BCP29143; BCP 29143; BCP-29143; 4-[3-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)propoxy]benzamide hydrochloride. CAS No. 1222097-72-4. Molecular formula: C17H25ClN2O2. Mole weight: 324.849. | |
| (S)-3-(Dimethylamino)pyrrolidine | (S)-3-(Dimethylamino)pyrrolidine is a useful research chemical. Alternative Names: (3S)-N,N-dimethyl-3-pyrrolidinamine; (3S)-(-)-3-(Dimethylamino)pyrrolidine; (S)-(-)-3-(Dimethylamino)pyrrolidine. Grades: 98%. CAS No. 132883-44-4. Molecular formula: C6H14N2. Mole weight: 114.19. | |
| (S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid | An intermediate in the synthesis of Lopinavir. Alternative Names: (2S)-(1-Tetrahydropyramid-2-one)-3-methylbutanoic acid; (2S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid; J-501007. CAS No. 192725-50-1. Molecular formula: C9H16N2O3. Mole weight: 200.23. | |
| (S)-3-Methylpiperidine hydrochloride | (S)-3-Methylpiperidine hydrochloride, a pharmacological precursor employed in the creation of numerous medicinal compounds spanning antihistamines, antiviral agents, and antipsychotics, is currently under examination for its possible efficacy in the remedy of neuropathic pain. Alternative Names: (3S)-3-methylpiperidine hydrochloride; (S)-3-Methylpiperidine HCl. CAS No. 155797-02-7. Molecular formula: C6H14ClN. Mole weight: 135.63. | |
| (S)-4-amino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. CAS No. 2183841-60-1. Molecular formula: C10H17N3O5S3. Mole weight: 355.45. | |
| (S)-4-Benzyl-3-propionyl-2-oxazolidinone-[d3] | (S)-4-Benzyl-3-propionyl-2-oxazolidinone-[d3]. Uses: Intermediate in the preparation of labelled albaconazole. Alternative Names: (4S)-3-(1-Oxopropyl)-4-(phenylmethyl)-2-oxazolidinone-d3; (+)-4-Benzyl-3-propionyl-2-oxazolidinone-d3; (4S)-4-Benzyl-3-propanoyloxazolidin-2-one-d3; (4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one-d3; (S)-N-Propionyl-4-benzyl-1,3-oxazolidin-2-one-d3; 3-[1-Oxopropyl]-4(S)-(phenylmethyl)-2-oxazolidinone-d3. CAS No. 156451-08-0. Molecular formula: C13H12D3NO3. Mole weight: 236.28. | |
| (S)-4-Boc-piperazine-2-acetonitrile | (S)-4-Boc-piperazine-2-acetonitrile (CAS# 1589082-06-3 ) is a useful research chemical. Alternative Names: 3-(cyanomethyl)-1-piperazinecarboxylic acid tert-butyl ester; tert-butyl 3-(cyanomethyl)piperazine-1-carboxylate. CAS No. 1589082-06-3. Molecular formula: C11H19N3O2. Mole weight: 225.29. | |
| (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid | (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid, a promising pharmacological agent for treating hypertension and cardiovascular diseases, exerts its therapeutic effect via potent antagonism of the angiotensin receptor. By impeding the interactions between angiotensin II and its receptors, this compound inhibits vasoconstriction, thereby potentially leading to a decrease in blood pressure and mitigating the progression of associated pathologies. The unique chemical structure of (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid provides a strong foundation for future drug development efforts aimed at optimizing its pharmacological profile for clinical use. Alternative Names: 5-({3-(Heptyloxy)-5-[(2S)-2-octanyloxy]benzyl}oxy)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[3-(heptyloxy)-5-[[(1S)-1-methylheptyl]oxy]phenyl]methoxy]-. Grades: ≥95%. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| SA-4503 dihydrochloride | SA-4503 is a potent sigma receptor agonist. SA-4503 may have effects on depressive symptoms such as agitation, loss of interest, and impaired cognition, which are mediated by NMDA receptors. SA 4503 attenuates cocaine-induced hyperactivity and enhances methamphetamine substitution for a cocaine discriminative stimulus. Alternative Names: SA 4503 dihydrochloride; 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride; SA4503 (dihydrochloride); Cutamesine dihydrochloride. Grades: 0.98. CAS No. 165377-44-6. Molecular formula: C23H34Cl2N2O2. Mole weight: 441.437. | |
| Sabizabulin | Sabizabulin is a tubulin polymerization inhibitor with anti-tumor activity. Alternative Names: ABI-231; ABI 231; ABI231; VERU 111. Grades: >98%. CAS No. 1332881-26-1. Molecular formula: C21H19N3O4. Mole weight: 377.4. | |
| Sacubitrilat | Sacubitrilat. CAS No. 149709-44-4. | |
| Sacubitril-[d4] | An isotope labelled AHU377, a methyl ester prodrug form of the neprilysin inhibitor LBQ657. Alternative Names: AHU377-d4; (alphaR,gammaS)-gamma-[(3-carboxy-1-oxopropyl-2,2,3,3-d4)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid,alpha-ethylester. Grades: ≥99% atom D. CAS No. 1884269-07-1. Molecular formula: C24H25D4NO5. Mole weight: 415.5. | |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Alternative Names: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. Grades: > 95%. CAS No. 1038925-00-6. Molecular formula: C18H19NO. Mole weight: 265.36. | |
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