BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Siponimod | Siponimod is a selective S1P1 and S1P5 agonist with EC50 of 0.39 nM and 0.98 nM, respectively. It has been approved by US FDA for the treatment of patients with active secondary progressive multiple sclerosis (SPMS). Alternative Names: BAF-312; BAF 312; BAF312; Siponimod; Mayzent; 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid. Grades: >98%. CAS No. 1230487-00-9. Molecular formula: C29H35F3N2O3. Mole weight: 516.6. |  |
| SIS3 HCl | SIS3 is a potent and specific inhibitor of Smad3 via inhibiting the effects of TGF-β1. SIS3 inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation with no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. It inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Alternative Names: (2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride. Grades: >98%. CAS No. 521984-48-5. Molecular formula: C28H27N3O3.HCl. Mole weight: 489.99. | |
| Sissotrin | Sissotrin is a natural flavonoid isolated from the herbs of Trifolium pratense L. It can impair glucose tolerance. Alternative Names: Biochanin A-beta-D-glucoside. Grades: >98%. CAS No. 5928-26-7. Molecular formula: C22H22O10. Mole weight: 446.4. | |
| Sisunatovir | Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Alternative Names: RV-521; RV 521; RV521. Grades: 99.08%. CAS No. 1903763-82-5. Molecular formula: C23H22F4N4O. Mole weight: 446.44. | |
| Sitagliptin EP Impurity B Phosphate | Sitagliptin EP Impurity B Phosphate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: Sitagliptin Analog 13 Phosphate; 4-Desfluoro Sitagliptin Phosphate; (R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate. CAS No. 1345822-87-8. Molecular formula: C16H19F5N5O5P. Mole weight: 487.32. | |
| Sitagliptin EP Impurity C Phosphate | Sitagliptin EP Impurity C Phosphate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: 5-Desfluoro Sitagliptin Phosphate; (R)-3-Amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one-phosphate. CAS No. 1345822-86-7. Molecular formula: C16H19F5N5O5P. Mole weight: 487.32. | |
| Sitostenone | Sitostenone is isolated from the roots of Xanthium sibiricum. Sitostenone has antioxidant activity and can be used in the treatment of androgen-dependent diseases, especially benign prostatic hyperplasia. Alternative Names: Stigmast-4-en-3-one; (24R)-24-Ethylcholest-4-en-3-one; (24R)-Stigmast-4-en-3-one; 4-En-3-stigmastone; NSC 49082; β-Rosasterol oxide; β-Sitost-4-en-3-one; β-Sitostenone; Δ4-Sitosterol-3-one; beta-sitostenone. Grades: >98%. CAS No. 1058-61-3. Molecular formula: C29H48O. Mole weight: 412.69. | |
| (S)-(+)-Ketoprofen-[13C,d3] | (S)-(+)-Ketoprofen-[13C,d3] is the labelled analogue of (S)-(+)-Ketoprofen, which is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 μM for human recombinant COX-1 and COX-2, respectively. Alternative Names: (S)-(+)-Ketoprofen-13C,d3; (+)-Ketoprofen-13C,d3; (S)-Ketoprofen-13C,d3; Dexketoprofen-d3; (S)-(+)-3-Benzoyl-α-methylbenzeneacetic Acid-13C,d3. Grades: > 98%. CAS No. 1330260-99-5. Molecular formula: C15[13C]H11D3O3. Mole weight: 258.29. | |
| (S)-(+)-Ketoprofen-[d3] Tromethamine Salt | (S)-(+)-Ketoprofen-[d3] Tromethamine Salt is the labelled analogue of Dexketoprofen Trometamol, which is a non-steroidal anti-inflammatory drug used for the treatment of mild to moderate pain. Alternative Names: (S)-(+)-Ketoprofen-d3 Tromethamine Salt; Dexketoprofen-d3 Trometamol; S-(+)-Ketoprofen-d3 Trometamol; (S)-Ketoprofen-d3 Trometamol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol (αS)-3-Benzoyl-α-methylbenzeneacetate-d3. Molecular formula: C20H22D3NO6. Mole weight: 378.43. | |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Alternative Names: SKF-86002; SKF 86002; SKF86002. 6-(4-fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole; 4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene. Grades: >98%. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.36. | |
| (S)-Lercanidipine-[d3] Hydrochloride | (S)-Lercanidipine-[d3] Hydrochloride is the labelled analogue of (S)-Lercanidipine Hydrochloride, which is a dihydropyridine calcium channel blocker. Alternative Names: (S)-Lercanidipine D3 Hydrochloride; (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)(methyl-d3)amino]-1,1-dimethylethyl Methyl Ester Hydrochloride; (S)-Lercanidipine-d3 monohydrochloride. Grades: ≥95%. CAS No. 1217740-02-7. Molecular formula: C36H39D3ClN3O6. Mole weight: 651.21. | |
| SLF | SLF is a cell-permeable analog of FK-506, an immunosuppressant with high affinity for FK-506 binding protein 12 (FKBP12). SLF binds tightly to FKBP but lacks the ability to inhibit calcineurin. Alternative Names: SLF Exclusive; Synthetic Ligand of FKBP. Grades: ≥98%. CAS No. 195513-96-3. Molecular formula: C30H40N2O6. Mole weight: 524.66. | |
| (S)-Lisinopril-[d5] | (S)-Lisinopril-[d5] is the labelled analogue of (S)-Lisinopril, an orally active angiotensin-converting enzyme (ACE) inhibitor. Alternative Names: ((S)-1-carboxy-3-(phenyl-d5)propyl)-L-lysyl-L-proline; Unk-Lys-Pro-OH-d5; (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline-d5. Grades: 98% by CP; 99% atom D. CAS No. 1356905-39-9. Molecular formula: C21H26D5N3O5. Mole weight: 410.52. | |
| Slu-PP-1072 | SLU-PP-1072 is a dual ERRα/γ inverse agonist that inhibits the warburg effect and induces apoptosis in prostate cancer cells. Grades: >98%. Molecular formula: C18H12N2O3S. Mole weight: 336.37. | |
| Slv319 | Slv319 is a potent antagonist of CB1 recceptor (Ki = 7.8 nM) used for the treatment of neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction and gastrointestinal disorders, as well as inhibits CP 55,940-induced hypotension and WIN 55,212-2-induced hypothermia in vivo. Alternative Names: Slv319; Slv 319; Slv-319; 3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide; CHEMBL158784. Grades: 98%. CAS No. 362519-49-1. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.399. | |
| SM-164 | SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein and binds to cIAP-1 and cIAP-2 proteins. It is developed as an anticancer agent. It plays its antitumor roles through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. It binds to cIAP-1 protein containing bothBIR2 and BIR3 domains, cIAP-2 BIR3 protein and XIAP protein containing both BIR2 and BIR3 domains. Alternative Names: SM 164; SM164; SM-164. Grades: >98%. CAS No. 957135-43-2. Molecular formula: C62H84N14O6. Mole weight: 1121.42. | |
| Smad3 Inhibitor, SIS3 | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Alternative Names: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Molecular formula: C28H27N3O3. Mole weight: 453.542. | |
| (S)-(+)-Mephenytoin | (S)-(+)-Mephenytoin is an S-isomer of Mephenytoin, which is known to target sodium channel protein type 5 subunit alpha. Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. It can be used to screen for such mutations by assaying its metabolites in urine. Alternative Names: (S)-5-Ethyl-3-methyl-5-phenylhydantoin; (+)-Mephenytoin; (5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione. Grades: > 95%. CAS No. 70989-04-7. Molecular formula: C12H14N2O2. Mole weight: 218.26. | |
| (S)-Methyl 2-(2-oxopyrrolidin-1-yl)butanoate | (S)-Methyl 2-(2-oxopyrrolidin-1-yl)butanoate. CAS No. 358629-51-3. | |
| SMIFH2 | SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. Alternative Names: SMIFH-2; SMIFH 2; 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; FH2 domain-IN-1. Grades: 98%. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. | |
| SN-011 | SN-011 is a potent and selective STING antagonist with IC50 of 76 nM. SN-011 binds with higher affinity to the cyclic dinucleotide (CDN)-binding pocket of STING than endogenous 2'3'-cGAMP. Alternative Names: GUN35901; N-(3-(4-Fluorophenylsulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.49. | |
| (S)-N1-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine.3HCl | (S)-N1-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine.3HCl. Alternative Names: (2S)-1-N-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine 3HCl. Grades: 98%. CAS No. 221640-06-8. Molecular formula: C13H26Cl3N3O. Mole weight: 346.72. | |
| [(S)-N-2'-Amino[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide | N-[(S)-2'-Amino-[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide is a chiral nitrogen ligand for enantioselective synthesis. Alternative Names: N-[(S)-2'-Amino-[1,1'-binaphthalen]-2-yl]-4-methylbenzenesulfonamide. Grades: 95%. CAS No. 933782-32-2. Molecular formula: C27H22N2O2S. Mole weight: 438.54. | |
| SNAP 94847 hydrochloride | SNAP 94847 is a potent melanin-concentrating hormone receptor 1 (MCH1) antagonist with > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Alternative Names: N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1781934-47-1. Molecular formula: C29H32F2N2O2·HCl. Mole weight: 515.03. | |
| (S)-Naproxen-[d3] | Naproxen-[d3] is the labelled analogue of Naproxen, which is a non-selective COX inhibitor. It is an anti-inflammatory agent with analgesic and antipyretic activities. It is commonly used for the treatment of rheumatoid arthritis and gout. Alternative Names: Naproxen D3; (S)-Naproxen-d3; (S)-6-Methoxy-d3-α-methyl-2-naphthaleneacetic Acid; po-Naproxen-d3; Aproxen-d3; Bonyl-d3; Diocodal-d3; Dysmenalgit-d3; Equiproxen-d3; Floginax-d3; Laraflex-d3; Laser-d3; MNPA-d3; Naprium-d3; Naprius-d3; Nycopren-d3; Panoxen-d3; Reuxen-d3; Veradol-d3; Xenar-d3; Xenar-CR-d3; D-2-(6-Methoxy-d3-2-naphthyl)propionic Acid; (αS)-6-(Methoxy-d3)-α-methyl-2-naphthaleneacetic Acid. Grades: ≥98%; ≥99% atom D. CAS No. 1094102-82-5. Molecular formula: C14H11D3O3. Mole weight: 233.28. | |
| (S)-N-Boc-3-(Hydroxymethyl)morpholine | An intermediate of BMS-599626, a selective and orally efficacious inhibitor of human epidermal growth factor receptor 1 and 2 kinases. Alternative Names: (S)-4-Boc-(3-hydroxymethyl)morpholine; (S)-tert-butyl 3-(hydroxymethyl)morpholine-4-carboxylate; (S)-N-BOC-3-hydroxymethylmorpholine; 3(S)-Hydroxymethyl-4-Boc-morpholine. Grades: 98%. CAS No. 714971-28-5. Molecular formula: C10H19NO4. Mole weight: 217.26. | |
| (S)-(+)-Nirvanol | (S)-(+)-Nirvanol is a Mephentoin metabolite with anticonvulsant and hypnotic properties. Uses: An anticonvulsant, hypnotic. a metabolite of mephentoin. Alternative Names: (+)-5-Ethyl-5-phenylhydantoin; S-Nirvanol. CAS No. 65567-34-2. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
| (S)-N-(tert-butoxycarbonyl)-N-(2-((tert-butoxycarbonyl)amino)-3-phenylpropyl)glycine-[d5] | (S)-N-(tert-butoxycarbonyl)-N-(2-((tert-butoxycarbonyl)amino)-3-phenylpropyl)glycine-[d5]. Uses: A labelled intermediate of ufp112. Alternative Names: (2S)-N-Boc-N'-Boc-amino-3-(phenyl-d5)propylglycine; (2S)-N-(2-Boc-amino-3-phenyl-d5-propyl) Boc-glycine. Grades: 95% atom D. CAS No. 1217601-60-9. Molecular formula: C21H27D5N2O6. Mole weight: 413.52. | |
| (S)-O-Demethylmetoprolol | (S)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Alternative Names: O-Demethylmetoprolol, (-)-; (S)-(-)-O-Demethylmetoprolol. CAS No. 131564-69-7. Molecular formula: C14H23NO3. Mole weight: 253.342. | |
| Sodium 1-Heptanesulfonate | Sodium 1-Heptanesulfonate is a reactant used in the preparation of surfactants for detergents or emulsifiers. Potential use in cancer therapy through NRF2-ARE interaction. Alternative Names: 1-Heptanesulfonic acid, sodium salt; Heptylsulfonic acid sodium salt; Sodium heptanesulfonate; Sodium n-heptylsulfonate; Sodium heptylsulfonate. CAS No. 22767-50-6. Molecular formula: C7H15O3SNa. Mole weight: 202.25. | |
| Sodium 2-((2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl)acetate | Sodium 2-((2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl)acetate is a biomedical product used in the research of neurological disorders and pain. This compound exhibits potential as an inhibitor of various enzymes involved in the central nervous system, making it a valuable candidate for drug development targeting diseases like Alzheimer's and Parkinson's. Alternative Names: 2-Piperazineacetic acid, 3,6-dioxo-5-(phenylmethyl)-, sodium salt (1:1), (2S,5S)-; 2-Piperazineacetic acid, 3,6-dioxo-5-(phenylmethyl)-, monosodium salt, (2S-cis)-. Grades: 95%. CAS No. 136983-81-8. Molecular formula: C13H13N2NaO4. Mole weight: 284.24. | |
| Sodium 3-hydroxybenzenesulfonate | Sodium 3-hydroxybenzenesulfonate, an organic chemical commonly employed in medicinal production and synthetic processes, exerts potent anti-inflammatory and analgesic actions. Such biochemical interventions are found efficacious in countering a panoply of afflictions including pain, fever, and inflammation symptomatic of arthritis and rheumatoid disorders. Alternative Names: sodium 3-hydroxybenzenesulfonate; Sodium m-phenolsulfonate. CAS No. 14278-60-5. Molecular formula: C6H5NaO4S. Mole weight: 196.16. | |
| Sodium 4-((2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methoxy)butane-1-sulfonate | Sodium 4-((2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methoxy)butane-1-sulfonate. Alternative Names: 4-(2,3-Dihydro-thieno[3,4-b][1,4]dioxin-2-ylmethoxy)-butane-1-sulfonic acid sodium salt; 1-Butanesulfonic acid, 4-[(2,3-dihydrothieno[3,4-b]-1,4-dioxin-2-yl)methoxy]-, sodium salt (1:1). Grades: 90%. CAS No. 204444-01-9. Molecular formula: C11H15NaO6S2. Mole weight: 330.35. | |
| Sodium decahydrodecaborate | Sodium decahydrodecaborate. CAS No. 12294-20-1. | |
| Sodium dicyclohexylsulfamate | Sodium dicyclohexylsulfamate. Alternative Names: N-Dicyclohexylamine sodium sulfonate; Sulfamic acid, dicyclohexyl-, sodium salt; Sulfamic acid, N,N-dicyclohexyl-, sodium salt (1:1). CAS No. 114723-27-2. Molecular formula: C12H22NNaO3S. Mole weight: 283.36. | |
| Sodium diethyl phosphate | Sodium diethyl phosphate can be used in a cosmetic composition for treating keratin materials. Alternative Names: Diethyl Phosphate Sodium Salt; Phosphoric acid, diethyl ester, sodium salt. CAS No. 2870-30-6. Molecular formula: C4H10NaO4P. Mole weight: 176.08. | |
| Sodium dodecahydrododecaborate | Sodium dodecahydrododecaborate. CAS No. 12008-78-5. | |
| Sodium hexanesulfonate | Sodium hexanesulfonate. CAS No. 2832-45-3. | |
| Sodium hydrogen (N-(4-aminobenzoyl)-l glutamate) | Sodium hydrogen (N-(4-aminobenzoyl)-l glutamate). CAS No. 97772-96-8. | |
| Sodium Phenylbutyrate | Phenylbutyrate is a well-known HDAC inhibitor, which increases gene transcription of a number of genes, and also exerts neuroprotective effects. Uses: Antineoplastic agents. Alternative Names: Sodium phenylbutyrate; 4-phenylbutyrate (4-PBA); 4-phenylbutyric acid; Buphenyl. Grades: >98%. CAS No. 1716-12-7. Molecular formula: C10H11O2.Na. Mole weight: 186.18. | |
| Sofosbuvir Impurity 35 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Alternative Names: (2'R)-2'-Chloro-2'-deoxy-2'-methyl-uridine; Chloro Sofosbuvir Desphosphate. Grades: > 95%. CAS No. 1496551-72-4. Molecular formula: C10H13ClN2O5. Mole weight: 276.68. | |
| Sofosbuvir impurity C | An impurity of Sofosbuvir, a medication used to treat hepatitis C. Alternative Names: Sofosbuvir impurity A; (2R)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate. CAS No. 1496552-28-3. Molecular formula: C22H29FN3O9P. Mole weight: 529.5. | |
| Sofosbuvir Impurity (GS-566500) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Alternative Names: L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-; N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine; PSI 352707. Grades: > 95%. CAS No. 1233335-78-8. Molecular formula: C13H19FN3O9P. Mole weight: 411.28. | |
| Sograzepide | Sograzepide, a benzodiazepin derivative, has been found to be a gastric receptor as well as CCK2 receptor antagonist that could be useful against chronic atrophic gastritis and gastric carcinoid at some extent. Alternative Names: YF476; YF-476; YF 476; Netazepide; Sograzepide; UNII-HOU4I0G29C; YF 476; CHEMBL324547; 1-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-pyridin-2-yl-3H-1,4-benzodiazepin-3-yl]-3-[3-(methylamino)phenyl]urea. Grades: ≥ 95% (HPLC). CAS No. 155488-25-8. Molecular formula: C28H30N6O3. Mole weight: 498.58. | |
| Solifenacin EP Impurity C | An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Alternative Names: Bis[(1S)-1,2,3,4-tetrahydro-1-phenyl-2(1H)-isoquinolinyl]-methanone; Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone. Grades: > 95%. CAS No. 1534326-81-2. Molecular formula: C31H28N2O. Mole weight: 444.58. | |
| Solifenacin EP Impurity F (RS isomer) | An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Alternative Names: (1R,3S)-Solifenacin Succinate; (S)-Quinuclidin-3-yl (R)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate. CAS No. 774517-20-3. Molecular formula: C23H26N2O2. Mole weight: 362.46. | |
| Solifenacin Succinate EP Impurity F | An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Alternative Names: (1R,3S)-Solifenacin Succinate; (R,S)-Solifenacin Succinate; Solifenacin Related Compound 2 Succinate; Solifenacin EP Impurity F Succinate; (S)-Quinuclidin-3-yl (R)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate succinate. Grades: 95%. CAS No. 1262506-09-1. Molecular formula: C27H32N2O6. Mole weight: 480.55. | |
| Solithromycin | Solithromycin (CAS 760981-83-7) is a novel ketolide antibiotic. Solithromycin (CAS 760981-83-7) can be used for anti-infection, and It is expected to be the first macrolide antibiotic available in intravenous, oral, and pediatric suspension formulations in over 20 years. Alternative Names: CEM101; CEM101; CEM 101; OP1068; OP1068; OP 1068; Solithromycin. Grades: >98%. CAS No. 760981-83-7. Molecular formula: C43H65FN6O10. Mole weight: 845.01. | |
| Songorine | C20-diterpenoid alkaloid from plants of the Aconitum genus, Ranunculaceae. Adrenergic and Serotonergic stimulant; CNS stimulant; antiarrhythmic. Alternative Names: Songorin; Bullatine G; Napellonine; Zongorine; (20R)-21-Ethyl-1α,15β-dihydroxy-4-methyl-16-methylene-7α,20-cycloveatchan-12-one. Grades: 98 % (NMR). CAS No. 509-24-0. Molecular formula: C22H31NO3. Mole weight: 357.49. | |
| Sonnerphenolic B | Sonnerphenolic B, a natural compound, has been found to showcase great potential in the realm of cancer and inflammation therapy owing to its proficient anti-tumor and anti-inflammatory activities. Clinical trials have furnished evidence that this compound is capable of stalling the proliferation of both breast cancer cells and human colon cancer cells. Besides, the compound can effectively alleviate inflammation in activated macrophages. Ultimately, Sonnerphenolic B demonstrates promise as a natural therapeutic agent for the management of cancer and inflammation. Alternative Names: (+)-Sonnerphenolic B. Grades: 97.5%. CAS No. 1627516-10-2. Molecular formula: C18H18O3. Mole weight: 282.34. | |
| Sootepin D | Sootepin D is a natural compound isolated from the fruits of Gardenia jasminoides Ellis. Alternative Names: Sootepin D; 1154518-97-4; methyl 3-[(1S,4R,5R,8S,9S,12R,13R)-12-(3-hydroxyprop-1-en-2-yl)-4,8-dimethyl-5-[(E,2R)-6-methyl-7-oxohept-5-en-2-yl]-13-tetracyclo[7.5.0.01,13.04,8]tetradecanyl]propanoate; CHEMBL552070; ZINC96023730. Grades: 93.0%. CAS No. 1154518-97-4. Molecular formula: C31H48O4. Mole weight: 484.721. | |
| Sophocarpine | Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Uses: Anti-tumor; anti-cancer; antiarrhythmic. Alternative Names: AS 604850; AS604850; AS-604850; 13,14-Didehydromatridin-15-one; (7aS,13aR,13bR,13cS)-2,3,6,7,7a,8,13,13a,13b,13c-decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one. Grades: >98%. CAS No. 6483-15-4. Molecular formula: C15H22N2O. Mole weight: 246.35. | |
| Sophoraflavanone G | Sophoraflavanone G is isolated from the roots of Sophora flavescens Ait. It is a novel small-molecule inhibitor of STAT. Uses: Anti-inflammatory effect; antimicrobial activity. Alternative Names: (S)-2,3-Dihydro-5,7-dihydroxy-2-(2,4-dihydroxyphenyl)-6-[(R)-5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one; (2S)-5,7-Dihydroxy-2,3-dihydro-2α-(2,4-dihydroxyphenyl)-8-[(R)-5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one. Grades: 98.5%. CAS No. 97938-30-2. Molecular formula: C25H28O6. Mole weight: 424.5. | |
| Sorafenib-[d3] | Sorafenib-[d3] is the labelled analogue of Sorafenib, which is a potent RAF kinase inhibitor and an antineoplastic. Alternative Names: Sorafenib-d3; Sorafenib-(methyl-d3); 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(methyl-d3)-2-pyridinecarboxamide. Grades: ≥98%; ≥99% atom D. CAS No. 1130115-44-4. Molecular formula: C21H13D3ClF3N4O3. Mole weight: 467.84. | |
| Sorafenib EP Impurity E | Sorafenib EP Impurity E. CAS No. 284670-98-0. | |
| Sorafenib EP Impurity G | Sorafenib EP Impurity G. CAS No. 18585-06-3. | |
| Sorafenib related compound 10 | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxylic Acid; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinic Acid; Sorafenib Hydroxydemethylamine. Grades: > 95%. CAS No. 1012058-78-4. Molecular formula: C20H13ClF3N3O4. Mole weight: 451.79. | |
| Sorbitan | Sorbitan. CAS No. 12441-09-7. | |
| Sorbitol dehydrogenase | Sorbitol dehydrogenase. CAS No. 9028-21-1. | |
| (S)-Oxybutynin-[d11] | A labelled impurity of Oxybutynin which is a prescription drug to reduce muscle spasms of the bladder and urinary tract. Alternative Names: 4-(Diethylamino)but-2-yn-1-yl (S)-2-(cyclohexyl-d11)-2-hydroxy-2-phenylacetate; (S)-Oxybutynin D11; Benzeneacetic acid, α-cyclohexyl-d11-α-hydroxy-, 4-(diethylamino)-2-butynyl ester, (αS)-; (S)-Oxybutynin-d11; Esoxybutynin-d11. Grades: > 95%. Molecular formula: C22H20NO3D11. Mole weight: 368.56. | |
| Soyacerebroside II | Soyacerebroside II isolated from the fruits of Glycine max. Uses: Antiulcerogenic activity. Alternative Names: (2R)-2-hydroxy-N-[(3R,4E,8Z)-3-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadeca-4,8-dien-2-yl]hexadecanamide. Grades: 95%. CAS No. 115074-93-6. Molecular formula: C40H75NO9. Mole weight: 714. | |
| Soyasapogenol A | Soyasapogenol A is a constituent of soya bean saponin. It belongs to the family of Oleanane Triterpenes. It showed a greater ability to inhibit proliferation of cultured Hep-G2 when compared to a total soyasaponin extract that did not contain any soyasapogenols. Alternative Names: Soyasapogenol M4; Soyasapogenol A(P); (4S)-Olean-12-ene-3β,21β,22β,23-tetrol; Olean-12-ene-3beta,21beta,22beta,24-tetrol. Grades: >98%. CAS No. 508-01-0. Molecular formula: C30H50O4. Mole weight: 474.72. | |
| Soyasaponin Ab | Soyasaponin Ab markedly inhibits adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes. Alternative Names: (3β,4β,21β,22β)-21,23-Dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranosiduronic acid; Acetylsoyasaponin A1. Grades: >98%. CAS No. 118194-13-1. Molecular formula: C67H104O33. Mole weight: 1437.54. | |
| Soyasaponin Af | Soyasaponin Af is a natural product found in Glycine max (soybean). Alternative Names: Acetylsoyasaponin A2; (3β,21β,22β)-21,24-Dihydroxy-22-{[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy}olean-12-en-3-yl 2-O-β-D-galactopyranosyl-β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, (3β,21β,22β)-21,24-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl 2-O-β-D-galactopyranosyl-. Grades: 98%. CAS No. 117230-32-7. Molecular formula: C61H94O28. Mole weight: 1275.38. | |
| Soyasaponin II | Soyasaponin II is found in Glycine max, it shows antiviral effects. Alternative Names: Soyasaponin Bc; Soyasaponin B-II; Soysaponin II. Grades: > 95%. CAS No. 55319-36-3. Molecular formula: C47H76O17. Mole weight: 913.09. | |
| Spadin trifluoroacetate salt | Spadin trifluoroacetate salt. | |
| Spegatrine | Spegatrine isolated from the roots of Rauvolfia verticillata. Grades: 0.98. CAS No. 47326-53-4. Molecular formula: C20H25N2O2. Mole weight: 325.4. | |
| SPHINX31 | SPHINX31 is a potent and selective inhibitor of serine / arginine-rich protein kinase 1 (SRPK1) (IC50 value of 6 nM). It inhibits SRPK1 activity and phosphorylation of serine / arginine splicing factor 1 (SRSF1), increasing expression of the anti-angiogenic VEGF-A165b splice variant in retinal pigment epithelial (RPE) cells. Alternative Names: SPHINX31; SPHINX-31; SPHINX 31; 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide. Grades: 99%. CAS No. 1818389-84-2. Molecular formula: C27H24F3N5O2. Mole weight: 507.51. | |
| SPI 112 | SPI 112 is a Shp2 PTP inhibitor. Alternative Names: SPI-112; SPI112; SPI 112. 3-[2-[5-[(4-fluorophenyl)methylsulfamoyl]-2-oxoindol-3-yl]hydrazinyl]benzoic acid. CAS No. 1051387-90-6. Molecular formula: C22H17FN4O5S. Mole weight: 468.459. | |
| SPI-112Me | SPI-112Me is a Shp2 PTP inhibitor. Alternative Names: methyl 3-[2-[5-[(4-fluorophenyl)methylsulfamoyl]-2-oxoindol-3-yl]hydrazinyl]benzoate. CAS No. 1243685-62-2. Molecular formula: C23H19FN4O5S. Mole weight: 482.486. | |
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