BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Sculponeatin A | Sculponeatin A can be extracted from the herbs of Rabdosia amethystoides. Alternative Names: 10,13-Dideoxy-10α,21-epoxy-5β-hydroxyenmein. Grades: >98%. CAS No. 85287-60-1. Molecular formula: C20H24O6. Mole weight: 360.4. |  |
| Sculponeatin N | Sculponeatin N can be isolated from the herbs of Rabdosia amethystoides. Alternative Names: Sculponeatin N; 1169805-98-4; [(1R,2S,4R,9R,10S,13R,14R)-2,14-dihydroxy-5,5,9-trimethyl-14-tetracyclo[11.2.1.01,10.04,9]hexadecanyl]methyl 3-methylbut-2-enoate; HY-N1258; ZINC96023599. Grades: >98%. CAS No. 1169805-98-4. Molecular formula: C25H40O4. Mole weight: 404.6. | |
| Scutebarbatine A | Scutebarbatine A, a natural diterpenoid isolated from the herbs of Scutellaria barbata D. Don, exhibits the activity of anti-tumor via mitochondria-mediated apoptosis on A549 cancer. Uses: Anti-tumor. Alternative Names: (1R,2S,3R,4R,4aS,8aR)-3-Hydroxy-3,4,8,8a-tetramethyl-4-[(E)-2-(5- oxo-2,5-dihydro-3-furanyl)vinyl]-1,2,3,4,4a,5,6,8a-octahydronapht halene-1,2-diyl dinicotinate. Grades: >96%. CAS No. 176520-13-1. Molecular formula: C32H34N2O7. Mole weight: 558.6. | |
| Scutebarbatine B | Scutebarbatine B, a natural diterpenoid isolated from the herbs of Scutellaria barbata D. Don, plays weak activities against HL60 cell lines. Alternative Names: Scutebarbatine B; 905929-95-5; [(1R,2S,3R,4R,4aS,8aR)-2-benzoyloxy-3-hydroxy-3,4,8,8a-tetramethyl-4-[(E)-2-(5-oxo-2H-furan-3-yl)ethenyl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] pyridine-3-carboxylate; CHEMBL3933122; HY-N1261. Grades: >98%. CAS No. 905929-95-5. Molecular formula: C33H35NO7. Mole weight: 557.6. | |
| Scutebata F | Scutebata F is from the herbs of Scutellaria barbata D.Don. Alternative Names: Barbatine C. Grades: >95%. CAS No. 1207181-62-1. Molecular formula: C30H37NO9. Mole weight: 555.6. | |
| (S)-Cystathionine-[d4] | (S)-Cystathionine-[d4]. Alternative Names: (S)-Cystathionine-d4; Allocystathionine-d4; (2S)-2-amino-4-(2-amino-2-carboxyethyl)sulfanylbutanoic acid-d4; (2S)-2-Amino-4-((2-amino-2-carboxyethyl)thio)butanoic acid-d4; S-[(2-RS)-2-Amino-2-carboxyethyl)-L-homocysteine-3,3,4,4-d4. Grades: 95% by HPLC; 98% atom D. Molecular formula: C7H10D4N2O4S. Mole weight: 226.28. | |
| SD-208 | SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII. Alternative Names: SD-208; SD 208; SD208; TGF-β RI Kinase Inhibitor V. Grades: >98%. CAS No. 627536-09-8. Molecular formula: C17H10ClFN6. Mole weight: 352.75. | |
| S-Deoxo ?6-Fulvestrant | S-Deoxo ?6-Fulvestrant is an impurity of Fulvestrant, which is a drug for breast cancer. Alternative Names: 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]estra-1,3,5(10),6-tetraene-3,17β-diol; S-Deoxo Fulvestrant Impurity E. CAS No. 2170200-16-3. Molecular formula: C32H45F5O2S. Mole weight: 588.75. | |
| S-Deoxo Fulvestrant | S-Deoxo Fulvestrant is a derivative of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Alternative Names: (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol. Grades: 95%. CAS No. 153004-31-0. Molecular formula: C32H47F5O2S. Mole weight: 590.77. | |
| SDZ285-428 | SDZ285-428 is a CYP24A1 inhibitor. Alternative Names: SDZ285 428; 4-(4-chlorophenyl)-N-(2-imidazol-1-yl-2-phenylethyl)benzamide; NVP-VID-400; NVP VID 400; NVP-VID-400; NVP-VID 400; NVP-VID400; SDZ285428; SDZ 285428; SDZ-285428; SDZ285-428; SDZ 285-428; SDZ-285-428. CAS No. 174262-13-6. Molecular formula: C24H20ClN3O. Mole weight: 401,894. | |
| Secalciferol | Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. lt mediates calcium and phosphorus homeostasis and inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. lt also can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Uses: Bone density conservation agents. Alternative Names: (24R)-24,25-Dihydroxyvitamin D3; Osteo D; (24R)-Hydroxycalcidiol. Grades: >98%. CAS No. 55721-11-4. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| Secnidazole Impurity B | An impurity of secnidazole. Secnidazole is a nitroimidazole anti-infective. Alternative Names: 1-((2-Hydroxy-1-methyl)ethyl)-2-methyl-5-nitroimidazole; β,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol. Grades: > 95%. CAS No. 56750-04-0. Molecular formula: C7H11N3O3. Mole weight: 185.18. | |
| Seco-Duocarmycin MB | Seco-Duocarmycin MB is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Alternative Names: (S)-tert-butyl (2-(1-(chloromethyl)-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)-1H-indol-5-yl)carbamate. Grades: ≥95%. Molecular formula: C27H26ClN3O4. Mole weight: 491.97. | |
| Seco-Duocarmycin SA | Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Alternative Names: (S)-Methyl 8-(chloromethyl)-4-hydroxy-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxylate. Grades: ≥95%. CAS No. 152785-82-5. Molecular formula: C25H24ClN3O7. Mole weight: 513.93. | |
| Seco-Duocarmycin TM | Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Alternative Names: (S)-(1-(chloromethyl)-5-hydroxy-1H-benzo[e]indol-3(2H)-yl)(5,6,7-trimethoxy-1H-indol-2-yl)methanone. Grades: ≥95%. CAS No. 1142188-60-0. Molecular formula: C25H23ClN2O5. Mole weight: 466.91. | |
| Secoisolariciresinol diglucoside | Secoisolariciresinol diglucoside. Alternative Names: (S,S)-Secoisolariciresinol diglucoside; (S,S)-SDG. Grades: 99.0%. CAS No. 257930-74-8. Molecular formula: C32H46O16. | |
| Secologanin dimethyl acetal | Secologanin dimethyl acetal is a natural iridoids found in the flower of Lonicera japonica Thunb, it exhibits antitumour activity against human promyelocytic leukemia (HL-60) cells in vitro and shows promising antifungal activity against Candida glaberata. Uses: Antifungal, antitumour. Alternative Names: Secologanoside-7- methyl ester, (-)-Secologanin dimethyl acetal. Grades: >96%. CAS No. 77988-07-9. Molecular formula: C19H30O11. Mole weight: 434.44. | |
| Securinine | Securinine is a natural alkaloid compound found in several plants. Alternative Names: (-)-securinin;securinan-11-one;securinin;Securinan-11-on. Grades: >98%. CAS No. 5610-40-2. Molecular formula: C13H15NO2. Mole weight: 217.264. | |
| Securinol A | Securinol A is a natural alkaloid compound found in several plants. Alternative Names: (5S,10aR,10bR,12R)-12-hydroxy-4,5,8,9,10,10a-hexahydro-2H,7H-5,10b-ethanofuro[2,3-a]quinolizin-2-one. Grades: >95%. CAS No. 5008-48-0. Molecular formula: C13H17NO3. Mole weight: 235.28. | |
| Sedanolide | Sedanolide is a natural phthalide compound originally isolated from seed oil of the Umbelliferae family, including celery. It is an inducer of glutathione S-transferase and inhibitor of chemically induced carcinogenesis. Alternative Names: 3-butyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one; trans-Sedanolide; 1(3H)-Isobenzofuranone, 3-butyl-3a,4,5,6-tetrahydro-. Grades: 98%. CAS No. 6415-59-4. Molecular formula: C12H18O2. Mole weight: 194.3. | |
| Seletalisib | Seletalisib is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by UCB. It is an immunomodulator. Phaes I clinical trials for Plaque psoriasis, phaes II clinical trials for Sjogren's syndrome and phaes III clinical trials for Immunodeficiency disorders is on-going. Alternative Names: UCB-5857; UCB 5857; UCB5857; (R)-3-(8-chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide. Grades: 98%. CAS No. 1362850-20-1. Molecular formula: C23H14ClF3N6O. Mole weight: 482.85. | |
| Seliciclib | Seliciclib is an orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic and antineoplastic activities. Seliciclib primarily inhibits CDK2/E, CDK2/A, CDK7 and CDK9 by competing for their ATP binding sites, leading to a disruption of cell cycle progression. In addition, this agent appears to interfere with CDK-mediated phosphorylation of the carboxy-terminal domain of RNA polymerase II, inhibiting RNA polymerase II-dependent transcription, which may result in the down-regulation of antiapoptotic proteins such as induced myeloid leukemia cell differentiation protein Mcl-1. CDKs, serine / threonine kinases that play an important role in cell cycle regulation, are overexpressed in various malignancies. Mcl-1 belongs to the Bcl-2 family of antiapoptotic proteins and is a protein crucial to the survival of a range of tumor cell types. Alternative Names: R-roscovitine; Roscovitin; Roscovitine; CYC202; CYC202; CYC 202; (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol. Grades: 98%. CAS No. 186692-46-6. Molecular formula: C19H26N6O. Mole weight: 354.44. | |
| Selonsertib | Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Alternative Names: 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide; GS-4997; GS4997; GS 4997. Grades: ≥98%. CAS No. 1448428-04-3. Molecular formula: C24H24FN7O. Mole weight: 445.5. | |
| Semaglutide Acetate | Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide. Grades: 98%. CAS No. 1997361-85-9. Molecular formula: C189H295N45O61. Mole weight: 4174. | |
| Semaglutide D-Leu26 | Semaglutide D-Leu26 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: D-Leu(26)-Semaglutide. Grades: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Semialactone | Semialactone isolated from the barks of Rhus javanica L. Alternative Names: (2S,3R,4S)-4-(2-{[(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoyl]oxy}et hyl)-2-(β-D-glucopyranosyloxy)-3-vinyl-3,4-dihydro-2H-pyran-5-car boxylic acid. Grades: 95%. CAS No. 366450-46-6. Molecular formula: C30H44O4. Mole weight: 468.7. | |
| Seneciphylline | Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. Alternative Names: Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione. Grades: >98%. CAS No. 480-81-9. Molecular formula: C18H23NO5. Mole weight: 333.4. | |
| Senkyunolide A | Senkyunolide A is isolated from Ligusticum chuanxiong Hort and shows cytoprotective, antiproliferative, and anti-tumor activity. Alternative Names: 1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)-; (3S)-3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone; 1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-; (-)-Sedanenolide; (S)-Sedanenolide; (S)-3-n-Butyl-4,5-dihydrophthalide; Sedanenolide; Senkyunolide. Grades: >95%. CAS No. 63038-10-8. Molecular formula: C12H16O2. Mole weight: 192.25. | |
| Senkyunolide G | Senkyunolide G is a natural compound found in several plants. Alternative Names: 3-Butyl-4,5-dihydro-3-hydroxy-1(3H)-isobenzofuranone. Grades: >95%. CAS No. 94530-85-5. Molecular formula: C12H16O3. Mole weight: 208.25. | |
| Senkyunolide I | Senkyunolide I isolated from the roots of Ligusticum chuanxiong hort. It has neuroprotective effect. Uses: Anti-oxidation and anti-apoptosis properties. Alternative Names: (6α,7β)-3-[(Z)-Butylidene]-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone; (3Z,6R,7R)-rel-3-Butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone. Grades: 0.98. CAS No. 94596-28-8. Molecular formula: C12H16O4. Mole weight: 224.3. | |
| Sephin 1 | Sephin 1 is a selective PPP1R15A inhibitor devoid of PPP1R15B and α2-adrenergic activity. In cells, Sephin 1 selectively disrupted the PPP1R15A-PP1c complex, thus prolonging eIF2α phosphorylation after stress, delaying translation recovery, and attenuated expression of stress genes such as the pro-apoptotic protein CHOP. In mice, Sephin 1 safely prevented the motor, morphological, and molecular defects of two otherwise unrelated protein-misfolding diseases. Uses: Potential treatment of protein misfolding disease. Alternative Names: Sephin1; Sephin-1. Grades: 99%. CAS No. 951441-04-6. Molecular formula: C8H9ClN4. Mole weight: 196.64. | |
| Sepiapterin | Sepiapterin. CAS No. 17094-01-8. | |
| (S)-(+)-Epichlorohydrin | S-enantiomer of Epichlorohydrin, an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. It is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer. Alternative Names: (S)-Epichlorohydrin; (S)-2-(Chloromethyl)oxirane; Oxirane, (chloromethyl)-, (2S)-. Grades: 99%; ee98%. CAS No. 67843-74-7. Molecular formula: C3H5ClO. Mole weight: 92.52. | |
| Serdemetan | Serdemetan, also known as JNJ-26854165, is an orally bioavailable, small-molecule HDM2 antagonist with potential antineoplastic activity. HDM2 antagonist JNJ-26854165 inhibits the binding of the HDM2-p53 complex to the proteasome, blocking the degradation of p53; p53 signaling and p53-mediated induction of tumor cell apoptosis may thus be restored. In addition to p53, degradation of other HDM2 client proteins may be inhibited. HDM2 (human homolog of double minute 2), a zinc finger protein, is a negative regulator of the p53 pathway; often overexpressed in cancer cells, this oncoprotein has been implicated in cancer cell proliferation and survival. Alternative Names: JNJ-26854165; JNJ26854165; JNJ 26854165. Grades: >98%. CAS No. 881202-45-5. Molecular formula: C21H20N4. Mole weight: 328.42. | |
| Sergliflozin etabonate | Sergliflozin etabonate is a SGLT-2 inhibitor as a promising agent for the type 2 diabetes and obesity treatment. Alternative Names: 2-(4-Methoxybenzyl)phenyl 6-O-(ethoxycarbonyl)-beta-D-glucopyranoside; GW 869682X; β-D-Glucopyranoside, 2-[(4-methoxyphenyl)methyl]phenyl, 6-(ethyl carbonate). Grades: 95%. CAS No. 408504-26-7. Molecular formula: C23H28O9. Mole weight: 448.46. | |
| Serpentinic acid | Serpentinic acid is a natural alkaloid found in the herbs of Catharanthus roseus. Alternative Names: (19alpha)-16-Carboxy-3,4,5,6,16,17-hexadehydro-19-methyloxayohimbanium inner. Grades: >97%. CAS No. 605-14-1. Molecular formula: C20H19N2O3. Mole weight: 335.38. | |
| Serpentinine | Serpentinine is isolated from the roots of Rauvolfia verticillata (Lour.) Baill. Alternative Names: 3,5,6,16,17-Pentadehydro-6-[(16S,19E)-19,20-didehydro-16-(methoxycarbonyl)corynan-17-yl]-16-methoxycarbonyl-19α-methyl-18-oxayohimban-4-ium. Grades: 97%. CAS No. 36519-42-3. Molecular formula: C42H44N4O5. Mole weight: 684.8. | |
| Sertaconazole nitrate | Sertaconazole nitrate is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections. Alternative Names: FI-7045; FI 7045; FI7045. Grades: >98%. CAS No. 99592-39-9. Molecular formula: C20H15Cl3N2OS·HNO3. Mole weight: 500.78. | |
| Sertraline 2,3-Dichloro Ketone Impurity | An impurity of sertraline. Sertraline is a selective serotonin reuptake inhibitor (SSRI) for the treatment of depression. Alternative Names: 4-(2,3-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone; rac 4-(2,3-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone. Grades: > 95%. CAS No. 152448-80-1. Molecular formula: C16H12Cl2O. Mole weight: 291.17. | |
| Sertraline Hydrochloride Racemic Mixture | Sertraline Hydrochloride Racemic Mixture. CAS No. 79617-89-3. | |
| Sesamin | Sesamin is a lignan isolated from the bark of Fagara plants and from sesame oil. It acts as a non-competitive inhibitor of Δ5-desaturase, and reduces cholesterol. Uses: Anti-fibrotic; anti-oxidative. Alternative Names: Fagarol; Sezamin; Asarinin; Pseudocubebin; 5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole. Grades: ≥ 98%. CAS No. 607-80-7. Molecular formula: C20H18O6. Mole weight: 354.358. | |
| sesamolin | Sesamin and sesamolin have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Alternative Names: (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. Grades: >98%. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36. | |
| Sessilifoline A | Sessilifoline A is a natural alkaloid found in the roots of Stemona japonica. Alternative Names: (1S,3S,5R,6S,7R,10S,11R,12R,16S)-11-Ethyl-7-methyl-3-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]-9,17-dioxa-2-azapentacyclo[10.5.0.01,5.02,16.06,10]heptadecan-8-one. Grades: >95%. CAS No. 929637-35-4. Molecular formula: C22H31NO5. Mole weight: 389.5. | |
| Setipiprant | Setipiprant is a potent, orally available and selective CRTH2 antagonist, which is a G protein-coupled receptor for PGD2. It may be a promising target for the treatment of allergic disorders. It was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics at multiple oral doses. It is a drug originally developed by Actelion, but it failed to show sufficient advantages and was discontinued from further development in this application. Later it was developed as a novel treatment for baldness by Kythera. Uses: Setipiprant may be a promising target for the treatment of allergic disorders. Alternative Names: ACT-129968; ACT 129968; ACT129968; 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid;ACT129968;2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid;8-Fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-acetic acid; KYTH-105; KYTH105; KYTH 105. Grades: >98 %. CAS No. 866460-33-5. Molecular formula: C24H19FN2O3. Mole weight: 402.42. | |
| (S)-(+)-Etodolac-[d3] | (S)-(+)-Etodolac-[d3] is the labelled S-enantiomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Alternative Names: (S)-(+)-Etodolac D3; (1S)-1,8-(Diethyl-d3)-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid; (+)-(S)-Etodolac-d3; (+)-Etodolac-d3; (+)-Etodolic Acid-d3; (S)-(+)-Etodolic Acid-d3; S-Etodolac-d3. Grades: >95%. CAS No. 1246818-32-5. Molecular formula: C17H18D3NO3. Mole weight: 290.38. | |
| Sevelamer Carbonate | Sevelamer Carbonate is a non-absorbed phosphate binding crosslinked polymer. Uses: Chelating agents. Alternative Names: KW-9144; KW 9144; KW9144. CAS No. 845273-93-0. | |
| SGC GAK 1 | SGC GAK 1 is a high affinity cyclin G associated kinase (GAK) inhibitor with >30-fold selectivity for GAK over a panel of other kinases. Alternative Names: SGC-GAK-1; BCP30478; 6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine. Grades: ≥99% by HPLC. CAS No. 2226517-76-4. Molecular formula: C18H17BrN2O3. Mole weight: 389.24. | |
| (S)-Glycidyl 3-Nitrobenzenesulfonate | (S)-Glycidyl 3-Nitrobenzenesulfonate (CAS# 115314-14-2) is a compound useful in organic synthesis. Alternative Names: 3-nitrobenzenesulfonic acid [(2S)-2-oxiranyl]methyl ester; [(2S)-oxiran-2-yl]methyl 3-nitrobenzenesulfonate. CAS No. 115314-14-2. Molecular formula: C9H9NO6S. Mole weight: 259.24. | |
| SH-4-54 | SH-4-54 is a potent STAT inhibitor with KD values of 300 nM and 464 nM for STAT3 and STAT5, respectively. It potently kills glioblastoma brain cancer stem cells (BTSCs). Alternative Names: 4-[(4-cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]benzoic acid. Grades: >98%. CAS No. 1456632-40-8. Molecular formula: C29H27F5N2O5S. Mole weight: 610.59. | |
| Shancigusin I | Shancigusin I is found in Bletilla striata. Grades: > 95%. CAS No. 1435488-35-9. Molecular formula: C28H34O14. Mole weight: 594.56. | |
| (S)-homo-β-alanine | (S)-Homo-β-alanine, an amino acid occurring naturally, acts as an intermediary in thymine metabolism. Its potential to regulate oxidative stress and inflammation marks it as a prospective treatment for cardiovascular disease and hypertension. Also, research suggests its involvement in the synthesis of neurotransmitter gamma-aminobutyric acid (GABA) in the brain. Alternative Names: (S)-beta-homoalanine. Grades: 95%. CAS No. 3775-72-2. Molecular formula: C4H9NO2. Mole weight: 103.11. | |
| S-Hydroxymethyl thiobenzoate | S-Hydroxymethyl thiobenzoate. CAS No. 23853-33-0. | |
| (S)-Ibrutinib | (S)-Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor. Alternative Names: 1-[(3S)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: > 95%. CAS No. 936563-97-2. Molecular formula: C25H24N6O2. Mole weight: 440.51. | |
| Sideroxylonal A | Sideroxylonal A can be extracted from the branch of Eucalyptus globulus. Alternative Names: 3-epi-Sideroxylonal B; 4-epi-Sideroxylonal C; 8-Formylloxophlebal A. Grades: >98%. CAS No. 145382-68-9. Molecular formula: C26H28O10. Mole weight: 500.5. | |
| Silanol-Terminated Polydiphenylsiloxane | Silanol-Terminated Polydiphenylsiloxane. CAS No. 63148-59-4. | |
| Silmitasertib | Silmitasertib is an orally bioavailable inhibitor of CK2 with potential antineoplastic activity. It inhibits proliferation in cancer cell lines overexpressing CK2. It suppresses survival and induces apoptosis of cancer stem cells including glioblastomas and acute myeloid leukemia cells. Alternative Names: CX-4945; CX 4945; 5-((3-Chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid. Grades: >98%. CAS No. 1009820-21-6. Molecular formula: C19H12ClN3O2. Mole weight: 349.774. | |
| Silodosin Dehydro Impurity | An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Alternative Names: 1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; Dehydro Silodosin. Grades: > 95%. CAS No. 175870-21-0. Molecular formula: C25H30F3N3O4. Mole weight: 493.53. | |
| Silodosin S-Isomer | An isomer of Silodosin, which is used in the treatment of the symptoms of an enlarged prostate (benign prostatic hyperplasia; BPH) in men. Alternative Names: Silodosin (S)-Isomer; (S)-Silodosin; 1-(3-Hydroxypropyl)-5-[(2S)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]indoline-7-carboxamide; (S)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide. CAS No. 2182279-45-2. Molecular formula: C25H32F3N3O4. Mole weight: 495.53. | |
| Silver 2-ethylhexanoate | Silver 2-ethylhexanoate. CAS No. 26077-31-6. | |
| Silybin B | An isomer of Silybin. Silybin, extracted from Silybum, is the major active constituent of silymarin. Uses: Antineoplastic agents, phytogenic. Alternative Names: (2R,3R)-2-[(2S,3S)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv.; NSC 227190; Silibinin B; Silybin a1. Grades: > 95%. CAS No. 142797-34-0. Molecular formula: C25H22O10. Mole weight: 482.44. | |
| Simeprevir | Simeprevir plays an important role in HCV replication. Data from phase I and II clinical trials of TMC-435350 (TMC 435350; TMC 435; TMC-435350) to date have shown that this agent is well tolerated as a once-daily oral therapy and provides potent antiviral activity in HCV genotype 1-infected subjects, with restoration of liver enzymes and no evidence of viral breakthrough. Alternative Names: TMC435; TMC 435; TMC-435; TMC435350; TMC-435350; TMC 435350. Grades: 98%. CAS No. 923604-59-5. Molecular formula: C38H47N5O7S2. Mole weight: 749.942. | |
| Simvastatin EP Impurity B | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: Acetyl simvastatin; 4'-Acetyl Simvastatin; Simvastatin Acetate; Simvastatin acetate ester; Simvastatin USP Related Compound B. Grades: 95%. CAS No. 145576-25-6. Molecular formula: C27H40O6. Mole weight: 460.62. | |
| Simvastatin EP Impurity D | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: Simvastatin USP Related Compound D; Simvastatin Dimer. Grades: > 95%. CAS No. 476305-24-5. Molecular formula: C50H76O10. Mole weight: 837.13. | |
| Simvastatin EP Impurity F | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grades: 95%. CAS No. 79952-44-6. Molecular formula: C24H36O5. Mole weight: 404.55. | |
| Simvastatin EP Impurity G | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: Methylene Simvastatin; 2''-Desethyl-2''-vinyl Simvastatin; Simvastatin USP Related Compound G. Grades: > 95%. CAS No. 1449248-72-9. Molecular formula: C25H36O5. Mole weight: 416.56. | |
| Simvastatin EP Impurity I | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: 2'-Ethyl Simvastatin. CAS No. 79902-42-4. Molecular formula: C23H34O5. Mole weight: 390.51. | |
| Simvastatin EP Impurity J | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: Simvastatin 4'-Methyl Ether; Cholestat Methyl Ether; Lipex Methyl Ether; Novo-Simvastatin Methyl Ether; Simvotin Methyl Ether. Grades: 95%. CAS No. 864357-88-0. Molecular formula: C26H40O5. Mole weight: 432.59. | |
| Simvastatin hydroxy acid sodium salt | A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Alternative Names: (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt; [1S-[1α(βS*,δS*),2α,6β,8β,8aα]]-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt; Simvastatin Sodium; Simvastatin Sodium Salt. Grades: > 95%. CAS No. 101314-97-0. Molecular formula: C25H39O6. Na. Mole weight: 435.59 22.99. | |
| Sinensin | Sinensin is a flavonoid compound found in the herbs of Cudrania cochinchinensis. Alternative Names: Aromadendrin-7-O-glucoside; Dihydrokaempferol 7-glucoside; Dihydrokaempferol 7-O-glucoside; Glucosyl-7-aromadendrin. Grades: >95%. CAS No. 28189-90-4. Molecular formula: C21H22O11. Mole weight: 450.4. | |
| SINOACUTINE | Sinoacutine, a natural alkaloid sourced from flora, boasts analgesic and anti-inflammatory properties backed by clinical research. The compound's potential in treating inflammatory diseases, including rheumatoid arthritis, has been subject to investigations. Sinoacutine's efficacy in regulating immune responses is attributable to its ability to obstruct the release of inflammatory cytokines, rendering it a viable candidate in the development of novel anti-inflammatory agents. Alternative Names: Sinoacutin. CAS No. 4090-18-0. Molecular formula: C19H21NO4. Mole weight: 327.4. | |
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