BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Spinosin | Spinosin ameliorated memory impairment induced through AβO, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. Therefore, Spinosin might be a useful agent against the amyloid b protein-induced cognitive dysfunction observed in AD patients. Uses: Anxiolytic. Alternative Names: spinosin; 2-(4-Hydroxyphenyl)-5-hydroxy-7-methoxy-6-[2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]-4H-1-benzopyran-4-one; 2''-O-β-D-Glucopyranosylswertisin; 6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-4',5-dihydroxy-7-methoxyflavone; 6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one; Spinosin A; 6-(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one; FlavoayaMenin. Grades: >98%. CAS No. 72063-39-9. Molecular formula: C28H32O15. Mole weight: 608.55. |  |
| Spiratisanin A | Spiratisanin A is extracted from the whole plants of Spiraea japonica. Alternative Names: Spiratisanin A; 1902173-16-3; [(1R,2R,4R,9R,10S,12S,13R)-13-Hydroxy-5,5,9,13-tetramethyl-2-tetracyclo[10.2.2.01,10.04,9]hexadecanyl]; (E)-3-phenylprop-2-enoate. Grades: 96.0%. CAS No. 1902173-16-3. Molecular formula: C29H40O3. Mole weight: 436.63. | |
| Spiratisanin B | Spiratisanin B is extracted from the whole plants of Spiraea japonica. Alternative Names: (5β,7α,8α,9β,10α,12α)-16-Hydroxyatisan-7-yl (2E)-3-phenylacrylate; 2-Propenoic acid, 3-phenyl-, (5β,7α,8α,9β,10α,12α)-16-hydroxyatisan-7-yl ester, (2E)-; Atisane-7,16-diol, 7-[(2E)-3-phenyl-2-propenoate], (5β,7α,8α,9β,10α,12α)-. Grades: 97.5%. CAS No. 1902173-19-6. Molecular formula: C29H40O3. Mole weight: 436.63. | |
| Spiratisanin C | Spiratisanin C is extracted from the whole plants of Spiraea japonica. Alternative Names: Atisane-16,20-diol, 20-[(2E)-3-phenyl-2-propenoate], (5β,8α,9β,10α,12α,16β)-; (5β,9β,10α,12α,16β)-16-Hydroxyatisan-20-yl (2E)-3-phenylacrylate; 2-Propenoic acid, 3-phenyl-, (5β,9β,10α,12α,16β)-16-hydroxyatisan-20-yl ester, (2E)-. Grades: 96.0%. CAS No. 1902173-22-1. Molecular formula: C29H40O3. Mole weight: 436.63. | |
| Spirosendan | Spirosendan, a new skeletal limonoid prossessing a spiro-structure, was isolated from the root bark of Melia toosendan (Meliaceae). Alternative Names: 2-Butenoic acid, 2-methyl-, (1R,1'S,2S,3'R,3'aR,4S,5S,5'aR,6'S,6'aS,9'S,10'aR,10'bR,10'cR)-1',3'-bis(acetyloxy)-4-(3-furanyl)decahydro-5,6'-dihydroxy-3'a,5,10'b-trimethylspiro[cyclopentane-1,7'-[7H-6a,9]methano[1H,4H]furo[2',3',4':4,5]naphtho[2,1-c]pyran]-2-yl ester, (2E)-; 220137-96-2. Grades: >98%. CAS No. 220137-96-2. Molecular formula: C35H46O11. Mole weight: 642.7. | |
| (S)-Praziquantel | S configuration of Praziquantel.Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Grades: > 95%. CAS No. 57452-97-8. Molecular formula: C19H24N2O2. Mole weight: 312.42. | |
| (S)-Praziquantel-[d11] | S configuration isotope labelled Praziquantel. Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Alternative Names: (11bS)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one-d11; (S)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; (+)-Praziquantel-d11; (S)-(+)-Praziquantel-d11; (S)-Praziquantel-d11; d-Praziquantel-d11. Grades: 98% HPLC. Molecular formula: C19H13D11N2O2. Mole weight: 323.48. | |
| SR1001 | Retinoic-acid-receptor-related orphan receptors (ROR) α and γ play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist at these receptors. SR 1001 has been shown to suppress IL-17 promoter driven transcriptional activity by inhibiting the interaction of co-activators such as TRAP220 nuclear receptor box 2 peptide (IC50 = 117 nM) and SRC2 with RORα and RORγ as well as by increasing the recruitment of corepressors such as NCoR. At 5 μM, SR 1001 inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs. A 25 mg/kg dose of SR 1001 twice/day delays the onset and the severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Alternative Names: SR 1001; SR-1001. Grades: >98%. CAS No. 1335106-03-0. Molecular formula: C15H13F6N3O4S2. Mole weight: 477.4. | |
| SR-3029 | SR-3029, a small molecule inhibitor that targets specificly CK1δ/CK1ε, was effective at reducing the growth of breast cancer in multiple mouse models without any signs of major toxicity. IC50=97 nM. Alternative Names: N-[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-morpholin-4-ylpurin-6-amine;SR-3029; SR 3029; SR3029;SCHEMBL15243359; SCHEMBL17132207; CS-5672; CS 5672; CS5672; HY-100011; 1454585-06-8. CAS No. 1454585-06-8. Molecular formula: C23H19F3N8O. Mole weight: 480.45. | |
| SR3335 | The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It has no effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis. Alternative Names: ML-176; SR 3335; SR-3335; ML176; ML 176. Grades: >98%. CAS No. 293753-05-6. Molecular formula: C13H9F6NO3S2. Mole weight: 405.34. | |
| SR-717 lithium | SR-717 is an agonist of stimulator of interferon genes (STING) for treating cancer. Alternative Names: SR 717 lithium; SR717 lithium. Grades: >98%. CAS No. 2375421-09-1. Molecular formula: C15H8F2LiN5O3. Mole weight: 351.2. | |
| (S,R)-Bortezomib Hydroxyisopentyl Amide Analog | (S,R)-Bortezomib Hydroxyisopentyl Amide Analog is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Alternative Names: N-((S)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (R)-Hydroxy Des(boric Acid) Bortezomib; Bortezomib Hydroxy Impurity (1R,2S)-Isomer. Grades: 98% by HPLC. CAS No. 289472-78-2. Molecular formula: C19H24N4O3. Mole weight: 356.43. | |
| Srpin340 | Srpin340 is an isonicotinamide compound that inhibits SRPK1 (Ki = 0.89 μM). It is about 10-fold less effective against SRPK2 and does not inhibit the related SRPKs, Clk1 and Clk4. Srpin340 suppresses the propagation of Sindbis virus in Vero cells and the replication of hepatitis C virus in Huh7/Rep-Feo-2a cells. Alternative Names: SRPIN-340; SRPIN 340. Grades: 99.82%. CAS No. 218156-96-8. Molecular formula: C18H18F3N3O. Mole weight: 349.35. | |
| (S,R,S)-AHPC-Me | E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component. Alternative Names: (S,R,S)-AHPC-Me; VHL ligand 2; E3 ligase Ligand 1A; 1-(2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-[1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide. CAS No. 1948273-02-6. Molecular formula: C23H32N4O3S. Mole weight: 444.59. | |
| (S,R,S)-AHPC-PEG1-azide | (S,R,S)-AHPC-PEG1-azide is a crosslinker-E3 ligase ligand conjugate consisting of a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Alternative Names: E3 ligase Ligand-Linker Conjugates 3; (S,R,S)-AHPC-PEG1-N3; (2S,4R)-1-((S)-2-(2-(2-Azidoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. CAS No. 2101200-09-1. Molecular formula: C26H35N7O5S. Mole weight: 557.67. | |
| SRT1720 hydrochloride | SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3. Alternative Names: SRT1720 HCl; SRT1720; N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide hydrochloride. Grades: >98%. CAS No. 1001645-58-4. Molecular formula: C25H23N7OS.HCl. Mole weight: 506.02. | |
| SRT2104 | SRT2104. CAS No. 1093403-33-8. | |
| (S,S)-Ethambutol-[d4] Dihydrochloride | (S,S)-Ethambutol-[d4] Dihydrochloride is the labelled salt of Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases. Alternative Names: (S,S)-Ethambutol D4 Dihydrochloride; (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}(1,1,2,2-D4)ethyl)amino]butan-1-ol dihydrochloride; (S,S)-Ethambutol-d4 bishydrochloride; (S,S)-Ethambutol D4 bishydrochloride; (2S,2S)-2,2-((ethane-1,2-diyl-d4)bis(azanediyl))bis(butan-1-ol) dihydrochloride; (S,S)-2,2'-(1,2-Ethanediyldiimino)-bis-1-butanol-d4 Dihydrochloride; Dexambutol-d4; Ebutol-d4; Etibi-d4; Etapiam-d4; Myambutol-d4; Mycobutol-d4; Sural-d4; Tibutol-d4; EMB-d4. Grades: 98%; > 99% atom D. CAS No. 1129526-19-7. Molecular formula: C10H20D4N2O2.2HCl. Mole weight: 281.26. | |
| (S,S)-(+)-N,N-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine | (S,S)-(+)-N,N-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine is a chiral nitrogen ligand for enantioselective synthesis. Alternative Names: (S,S)-Jacobsen' s ligand; (1S,2S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine. Grades: 98%. CAS No. 135616-36-3. Molecular formula: C36H54N2O2. Mole weight: 546.83. | |
| (S)-SPINOL | (S)-SPINOL, a chiral ligand crucial in asymmetric catalysis for pharmaceutical and agrochemical synthesis. Its application extends to the creation of diverse biologically active substances, indicating promise in cancer and disease treatment endeavors. Alternative Names: 1,1'-Spirobi[1H-indene]-7,7'-diol, 2,2',3,3'-tetrahydro-, (1S)-; (1S)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol; (S)-1,1'-Spirobiindane-7,7'-diol; (S)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol. Grades: ≥95%. CAS No. 223259-63-0. Molecular formula: C17H16O2. Mole weight: 252.31. | |
| Stachydrine hydrochloride | Stachydrine hydrochloride is extracted from the flower of Chrysanthemum parthenium. It promoted the protein expression of IL-12 and IL-6, as well as the mRNA expression of T-bet and RORγt, while inhibiting the mRNA expression of GATA-3 and Foxp3. Alternative Names: Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride (1:1), (2S)-; Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride, (2S)-; Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride, (S)-; Stachydrine, chloride; Cadabine hydrochloride; (S)-2-Carboxy-1,1-dimethylpyrrolidinium chloride; (S)-2-Carboxy-1,1-dimethylpyrrolidin-1-ium chloride. Grades: >98%. CAS No. 4136-37-2. Molecular formula: C7H14ClNO2. Mole weight: 179.64. | |
| StemRegenin 1 | StemRegenin 1 is an aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM. It has been reported to promote hematopoietic stem cell expansion. Alternative Names: 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol; SR1. Grades: >98%. CAS No. 1227633-49-9. Molecular formula: C24H23N5OS. Mole weight: 429.542. | |
| Stephanine | Stephanine is isolated from the root of Stephania japonica. It inhibits anococcygeus muscle contraction induced by phenylephrine, so Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker. Alternative Names: 8-Methoxy-1,2-methylenedioxyaporphine. Grades: 98%. CAS No. 517-63-5. Molecular formula: C19H19NO3. Mole weight: 309.4. | |
| Steviol | Steviol is a diterpenoiic carboxylic alcohol and is isolated from the herbs of Stevia rebaudiana. It is the aglycon derivative of natural sweetener steviol glycosides and is found to be highly mutagenic compared to Stevioside. It inhibits the proliferation of the gastrointestinal cancer cells and the human osteosarcoma U2OS cell line in a dose- and time-dependent manner. It also inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4. It increases CYP3A29 expression and enhances pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity. It can be used to treat polycystic kidney disease. It can promote proteasome and lysosome-mediated AQP2 degradation and slow cyst growth by reducing AQP2 transcription. Alternative Names: (4α)-13-Hydroxy-kaur-16-en-18-oic Acid; 13-Hydroxy-kaur-16-en-18-oic Acid; 13-Hydroxykaurenoic Acid; Ent-13-hydroxy-kauran-16-en-19-oic Acid; 1H-2,10a-Ethanophenanthrene; 13-O-Glucosylsteviol; Hydroxydehydrostevic Acid; (4R,4aS,6aR,9S,11aR,11bS)-9-hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid. Grades: 98.5%. CAS No. 471-80-7. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| Stigmast-4-ene-3β,6β-diol | Stigmast-4-ene-3β,6β-diol is a natural steroid found in the barks of Ailanthus altissima. Alternative Names: (3S,6R,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol. Grades: >97%. CAS No. 113626-76-9. Molecular formula: C29H50O2. Mole weight: 430.7. | |
| Stigmasta-4,22-dien-3-one | Stigmasta-4,22-dien-3-one can be found in the flower of Magnolia biondii. It has antioxidant activity. Uses: Antioxidant. Alternative Names: 4,22-Cholestadien-24-ethyl-3-one. Grades: >98%. CAS No. 55722-32-2. Molecular formula: C29H46O. Mole weight: 410.7. | |
| Stigmastan-3β-ol | Stigmastan-3β-ol. CAS No. 19466-47-8. | |
| Stigmastane-3,6-dione,(5a)- | Stigmastane-3,6-dione usually comes from the roots of Piper nigrum. Alternative Names: 5α-Stigmastane-3,6-dione. Grades: >98%. CAS No. 22149-69-5. Molecular formula: C29H48O2. Mole weight: 428.7. | |
| Stigmastane-3β,5α,6β-triol | Stigmastane-3β,5α,6β-triol isolated from the fruits of Evodia rutaecarpa. Alternative Names: alpha-stigmastane-3 beta,5,6 beta-triol 3-monobenzoate. Grades: 0.98. CAS No. 20835-91-0. Molecular formula: C29H52O3. Mole weight: 448.7. | |
| Streptavidin | Streptavidin is a tetrameric bacterial protein isolated from Streptomyces avidinii. Streptavidin shows high affinity for biotin. Alternative Names: Streptavidin, Avidin, Streptomyces avidinii. CAS No. 9013-20-1. | |
| Stylopine hydrochloride | Stylopine hydrochloride is a natural compound isolated from the leaves of Chelidonium majus L. Alternative Names: Tetrahydrocoptisine hydrochloride. Grades: 98.5%. CAS No. 96087-21-7. Molecular formula: C19H18ClNO4. Mole weight: 359.806. | |
| SU 4312 | SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 = 0.8 and 19.4 μM, respectively) wirth selectivity over EGFR and c-Src tyrosine kinases. Alternative Names: SU4312; SU-4312; 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-; 2-Indolinone, 3-[p-(dimethylamino)benzylidene]-; 3-(4-Dimethylaminobenzylidenyl)-2-indolinone; 3-[[4-(Dimethylamino)phenyl]methylidene]-2,3-dihydro-1H-indol-2-one; DMBI; NSC 86429. Grades: ≥95%. CAS No. 5812-7-7. Molecular formula: C17H16N2O. Mole weight: 264.33. | |
| SU 4942 | SU 4942 is a modulator of tyrosine kinase signal transduction, targeting VEGF and ECGF. Alternative Names: SU 4942; SU-4942; SU4942. 3-(4-Bromobenzylidene)indoline-2-one. CAS No. 76086-99-2. Molecular formula: C15H10BrNO. Mole weight: 300.155. | |
| SU 5201 | SU 5201 is an inhibitor of IL-2 production. Alternative Names: (3Z)-3-[(3,4-Dichlorophenyl)methylidene]-1H-indol-2-one; NSC 247030; NSC-247030; NSC247030; SU 5201; SU5201; SU-5201. CAS No. 114727-43-4. Molecular formula: C15H9Cl2NO. Mole weight: 290.143. | |
| SU 5205 | SU5205 is a VEGFR2 inhibitor. Alternative Names: 3-(4-fluorobenzylidene)indolin-2-one; SU 5205; SU-5205; SU5205. CAS No. 3476-86-6. Molecular formula: C15H10FNO. Mole weight: 239.249. | |
| SU 5214 | SU 5214 is a modulator of tyrosine kinase signal transduction. Alternative Names: SU 5214; SU5214; SU-5214; (3Z)-3-o-Anisylideneoxindole; 3-(2-Methoxy-benzylidene)-3H-indol-2-ol; (3Z)-3-[(2-methoxyphenyl)methylidene]-1H-indol-2-one. CAS No. 186611-04-1. Molecular formula: C16H13NO2. Mole weight: 251.285. | |
| SU5402 | SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor. Alternative Names: SU-5402; SU 5402. Grades: 0.98. CAS No. 215543-92-3. Molecular formula: C17H16N2O3. Mole weight: 296.32054. | |
| SU5408 | A potent, selective and cell-permeable inhibitor of VEGFR2 kinase(IC50= 70 nM) with little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 μM). Alternative Names: SU-5408; SU 5408; SU5408; ethyl 2,4-dimethyl-5-[(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate; VEGFR2 Kinase Inhibitor I; IN1018. CAS No. 15966-93-5. Molecular formula: C18H18N2O3. Mole weight: 310.35. | |
| SU 5614 | SU4984 is a FLT3 inhibitor that induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3. It also exhibits inhibitory effects on C-KIT, VEGFR, and PDGFRβ. Alternative Names: SU5614; SU 5614; SU5614; (3Z)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one. CAS No. 1055412-47-9. Molecular formula: C15H13ClN2O. Mole weight: 272.73. | |
| Suavioside A | Suavioside A is extracted from the leaves of Rubus suavissimus. It has sweet taste and may be used as a sweetener. Alternative Names: 17-(β-D-Glucopyranosyloxy)kaurane-3β,16α-diol. Grades: 98.0%. CAS No. 133740-37-1. Molecular formula: C26H44O8. Mole weight: 484.63. | |
| Succinic Acid Monobenzyl Ester | Succinic Acid Monobenzyl Ester (CAS# 103-40-2) is a useful research chemical. Alternative Names: 4-oxo-4-phenylmethoxybutanoic acid; 4-oxo-4-phenylmethoxybutanoic acid. Grades: 98%. CAS No. 103-40-2. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Sudan Red 7B-[d5] | Sudan Red 7B-[d5] is an isotope labelled Sudan Red 7B, a non-fluorescent red stain. Alternative Names: Sudan Red 7B-d5; N-Ethyl-D5-1-[2-[4-(2-phenyldiazenyl)phenyl]diazenyl]-2-naphthalenamine. Molecular formula: C24H16D5N5. Mole weight: 384.50. | |
| Sufugolix | Sufugolix, also known as TAK-013, is a highly potent, non-peptide and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.1 nM. Sufugolix was under development to treat endometriosis and uterine leiomyoma and undergone testing in a phase II clinical study in both of these indications, but was subsequently discontinued. Alternative Names: 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea; 5-(N-benzyl-N-methylaminomethyl)-1--(2,6-difluorobenzyl)-6-(4-(3-methoxyureido)phenyl)-3-phenylthieno(2,3-d)pyrimidine-2,4(1H,3H)-dione; Sufugolix; TAK-013; TAK013; TAK 013. CAS No. 308831-61-0. Molecular formula: C36H31F2N5O4S. Mole weight: 667.72. | |
| Sugammadex-1 | Sugammadex-1 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Molecular formula: C48H72O32I8. Mole weight: 2176.3. | |
| Sulbactam EP Impurity C | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Alternative Names: 6-Bromopenicillanic acid sulfone (USP); Brobactam S,S-Dioxide; 6beta-Bromopenicillanic acid 1,1-dioxide; (2S,5R,6R)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide. Grades: 95%. CAS No. 75527-87-6. Molecular formula: C8H10BrNO5S. Mole weight: 312.14. | |
| Sulbactam EP Impurity D | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Uses: Beta-lactamase inhibitors. Alternative Names: Brobactam; 6-Bromopenicillanic Acid; [2S-(2α,5α,6β)]-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid. Grades: 90%. CAS No. 26631-90-3. Molecular formula: C8H10BrNO3S. Mole weight: 280.14. | |
| Sulfabenzamide-[d4] | Sulfabenzamide-[d4] is the labelled analogue of Sulfabenzamide, an antimicrobial agent. Alternative Names: Sulfabenzamide-d4; N-[(4-Aminophenyl)sulfonyl]-benzamide-d4; N-(Benzoyl)-4-aminobenzenesulfonamide-d4; N1-Benzoylsulfanilamide-d4. Molecular formula: C13H8D4N2O3S. Mole weight: 280.34. | |
| Sulfadiazine-[13C6] | Sulfadiazine-[13C6] is the labelled analogue of Sulfadiazine, which is an antibiotic. It is commonly used to treat urinary tract infections and burns. Alternative Names: Sulfadiazine-13C6; 4-Amino-N-pyrimidin-2-yl-benzene-13C6-sulfonamide; 4-Amino-N-2-pyrimidinylbenzenesulfonamide-13C6; 2-(4-Aminobenzenesulfonamido-13C6)pyrimidine; 2-Sulfanilylaminopyrimidine-13C6; Adiazin-13C6; Adiazine-13C6; Debenal-13C6; Liquadiazine-13C6; Microsulfon-13C6; Sulfazine-13C6; Sulfolex-13C6; Sulfadiazine-(phenyl-13C6). Grades: 95% by HPLC; 98% atom 13C. CAS No. 1189426-16-1. Molecular formula: C4[13C]6H10N4O2S. Mole weight: 256.21. | |
| Sulfadiazine-[d4] | Sulfadiazine-[d4] is the labelled analogue of Sulfadiazine. Sulfadiazine is an antibiotic. It is commonly used to treat urinary tract infections and burns. Alternative Names: Sulfadiazine D4; 4-Amino-N-2-pyrimidinylbenzenesulfonamide-d4; 2-(4-Aminobenzenesulfonamido-d4)pyrimidine; 2-Sulfanilylaminopyrimidine-d4. Grades: 95% by HPLC; 95% atom D. CAS No. 1020719-78-1. Molecular formula: C10H6D4N4O2S. Mole weight: 254.30. | |
| Sulfadimethoxine-[d6] | An isotope labelled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antimicrobial medication used in veterinary medicine. Alternative Names: N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide-d6; 2,4-Dimethoxy-6-sulfanilamido-1,3-diazine-d6; NSC 683544-d6; Neostreptal-d6; Omnibon-d6; Persulfen-d6; Redifal-d6. Grades: 95% by HPLC; 98% atom D. CAS No. 73068-02-7. Molecular formula: C12H8D6N4O4S. Mole weight: 316.37. | |
| Sulfadimidine-[13C6] | Sulfadimidine-[13C6] is the labelled analogue of Sulfadimidine, which is a sulfonamide antibacterial. It competitively inhibits dihydropteroate synthase and interferes with folic acid synthesis. Alternative Names: Sulfadimidine-13C6; 4-Amino-N-(4,6-dimethylpyrimidin-2-yl)-benzene-13C6-sulfonamide; 4-Amino-N-(4,6-Dimethyl-2-pyrimidinyl)benzenesulfonamide-13C6; Azolmetazin-13C6; Sulfamezathine-13C6; Diazil-13C6. Grades: 95% by HPLC; 98% atom 13C. CAS No. 77643-91-5. Molecular formula: C6[13C]6H14N4O2S. Mole weight: 284.29. | |
| Sulfadimidine-[d4] | Sulfadimidine-[d4] is the labelled analogue of Sulfadimidine. Sulfadimidine is a sulfonamide antibacterial. It competitively inhibits dihydropteroate synthase, interfering with folate synthesis. Alternative Names: Sulfadimidine D4; 4-Amino-N-(4,6-Dimethyl-2-pyrimidinyl)benzenesulfonamide-d4; Azolmetazin-d4. Grades: 95% by HPLC; 95% atom D. CAS No. 1020719-82-7. Molecular formula: C12H10D4N4O2S. Mole weight: 282.35. | |
| Sulfadoxine-[d3] | Sulfadoxine-[d3] is the labelled analogue of Sulfadoxine, which is an antibacterial. It competitively inhibits dihydropteroate synthase and interferes with folic acid synthesis. Alternative Names: Sulfadoxine-D3; 4-Amino-N-(5-methoxy-6-methoxy-D3-pyrimidin-4-yl)-benzenesulfonamide; 4-Amino-N-[5-methoxy-6-(methoxy-d3)-4-pyrimidinyl]benzenesulfonamide. Grades: 95% by HPLC; 98% atom D. CAS No. 1262770-70-6. Molecular formula: C12H11D3N4O4S. Mole weight: 313.35. | |
| Sulfadoxine-[d4] | Sulfadoxine-[d4] is the labelled analogue of Sulfadoxine. Sulfadoxine is an antibacterial. It competitively inhibits dihydropteroate synthase, interfering with folate synthesis. Alternative Names: Sulfadoxine D4; 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide-d4; N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide-d4. Grades: 95% by HPLC; 95% atom D. CAS No. 1330266-05-1. Molecular formula: C12H10D4N4O4S. Mole weight: 314.36. | |
| Sulfaguanidine-[d4] | Sulfaguanidine-[d4] is the labelled analogue of Sulfaguanidine. Sulfaguanidine is a sulfonamide used as an anti-infective agent. Alternative Names: Sulfaguanidine-d4. Molecular formula: C7H10N4O2S. Mole weight: 218.27. | |
| Sulfamethizole-[d4] | An isotope labelled Sulfamethizole. Sulfamethizole is a sulfonamide antibiotic. It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Alternative Names: 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole-d4; 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole-d4; 4-Amino-N-(5-methyl-[1,3,4]thiadiazol-2-yl)benzenesulfonamide-d4; 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole-d4; Ayerlucil-d4; Famet-d4; Lucosil-d4; Methazol-d4; Microsul-d4; N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-aminobenzenesulfonamide-d4-d4; N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide-d4; Renasul-d4; Rufol-d4; Salimol-d4; Sulfamethiazole-d4; Sulfamethizol-d4; Sulfamethylthiadiazole-d4; Sulfapyelon-d4; Sulfstat-d4; Sulfurine-d4; Sulphamethizole-d4; Tetracid-d4; Thidicur-d4; Thiosulfil-d4; Thiosulfil Forte-d4; Ultrasul-d4; Urocydal-d4; Urodiaton-d4; Urolucosil-d4; Urosulfin-d4; VK 53-d4; N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide-d4. Grades: > 95%. CAS No. 2470130-12-0. Molecular formula: C9H6D4N4O2S2. Mole weight: 274.36. | |
| Sulfamethoxazole-[d4] | Sulfamethoxazole-[d4] is the labelled analogue of Sulfamethoxazole. Sulfamethoxazole is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Alternative Names: Sulfamethoxazole D4; 4-Amino-N-(5-methyl-3-isoxazolyl)(benzene-d4)sulfonamide; 3-(p-Amino(benzene-d4)sulfonamido)-5-methylisoxazole. Grades: 95% by HPLC; 95% atom D. CAS No. 1020719-86-1. Molecular formula: C10H7D4N3O3S. Mole weight: 257.30. | |
| Sulfamethoxypyridazine-[d3] | Sulfamethoxypyridazine-[d3] is the labelled analogue of Sulfamethoxypyridazine, which is a long-acting sulfonamide antibiotic. It is used for treatment of Dermatitis herpetiformis. Alternative Names: Sulfamethoxypyridazine-D3; 4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide-d3; 3-Methoxy-6-sulfanilamidopyridazine-d3; 6-Sulfanilamido-3-methoxypyridazine-d3; Sultirene-d3; N1-(6-Methoxy-3-pyridazinyl)sulfanilamide-d3; Paramid-d3; Paramid Supra-d3; 4-Amino-N-(6-methoxy-D3-pyridazin-3-yl)-benzenesulfonamide. Grades: 95% by HPLC; 98% atom D. CAS No. 1172846-03-5. Molecular formula: C11H9D3N4O3S. Mole weight: 283.32. | |
| Sulfamethoxy pyridazine-[d4] | Isotopic labelled Sulfamethoxy pyridazine. Sulfamethoxy pyridazine is a long-acting sulfonamide antibiotic. It is used for treatment of Dermatitis herpetiformis. Alternative Names: 4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide-d4; 3-Methoxy-6-sulfanilamidopyridazine-d4; 6-Sulfanilamido-3-methoxypyridazine-d4; Sultirene-d4; N1-(6-Methoxy-3-pyridazinyl)sulfanilamide-d4; Paramid-d4; Paramid Supra-d4. Grades: >98%. Molecular formula: C11H8D4N4O3S. Mole weight: 284.33. | |
| Sulfapyridine-[d4] | Sulfapyridine-[d4] is the labelled analogue of Sulfapyridine, which could be used as an antibacterial agent. Alternative Names: Sulfapyridine D4; 4-Amino-N-2-pyridinyl(benzene-d4)sulfonamide. Grades: 95% by HPLC; 95% atom D. CAS No. 1189863-86-2. Molecular formula: C11H7D4N3O2S. Mole weight: 253.31. | |
| Sulfocostunolide B | Sulfocostunolide B can be found in the roots of Saussurea lappa. Alternative Names: Sulfocostulide B. Grades: >98%. CAS No. 1059671-65-6. Molecular formula: C15H20O5S. Mole weight: 312.4. | |
| Sulfo-Cy5 amine hydrochloride | Sulfo-Cy5 amine hydrochloride is a water soluble amino dye for enzymatic transamination labeling, and other coupling with electrophiles. Alternative Names: Sulfo-Cyanine5 amine hydrochloride. Grades: 95%. Molecular formula: C38H53ClN4O7S2. Mole weight: 777.43. | |
| Sulfo-Cy5 DBCO | Sulfo-Cy5 DBCO is a water-soluble linker of Cyanine5 fluorophore. DBCO group enables copper free biocompatible Click Chemistry with fast reaction kinetics and good stability. This reagent is compatible to a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes. Alternative Names: 1-[6-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-6-oxohexyl]-2-[(1E,3E,5E)-5-[3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)indol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate; Sulfo-Cy5DBCO. Grades: 95%. CAS No. 1564286-24-3. Molecular formula: C52H56N4O11S3. Mole weight: 1009.2. | |
| Sulfo-Cyanine 5 Carboxylic Acid (ethyl) | Sulfo-Cyanine 5 Carboxylic Acid (ethyl) is a highly intricate biomedical entity that is availed for imaging and diagnostics within the realm of biomedicine. Serving as a pervasive fluorescent staining agent for biomolecular labeling (e.g., proteins and nucleic acids), this multifaceted acid assumes indispensable significance across an array of scientific pursuits. From facilitating drug delivery mechanisms to efforts to discover disease and monitor complex cellular activities, it has greatly advanced research progress. Grades: 98%. CAS No. 146368-11-8. Molecular formula: C33H40N2O8S2. Mole weight: 656.8. | |
| Sulfopin | Sulfopin is a selective Pin1 inhibitor. Sulfopin is a chemical probe suitable for assessment of Pin1-dependent pharmacology in cells and in vivo, and that Pin1 warrants further investigation as a potential cancer drug target. Alternative Names: PIN1-3. CAS No. 2451481-08-4. Molecular formula: C11H20ClNO3S. Mole weight: 281.80. | |
| Sulindac Sulfide | One of the active metabolites of Sulindac that is a non-steroidal anti-inflammatory agent. Alternative Names: (E/Z)-Sulindac sulfide; 5-Fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid. Grades: 95%. CAS No. 32004-67-4. Molecular formula: C20H17FO2S. Mole weight: 340.42. | |
| Sulpiride EP Impurity B | Sulpiride EP Impurity B. CAS No. 33045-52-2. | |
| SUN11602 | SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of basic fibroblast growth factor. In primary cultures of rat cerebrocortical neurons, SUN11602 and bFGF prevented glutamate-induced neuronal death. Alternative Names: SUN11602; SUN-11602; SUN 11602. 4-[[4-[[2-(4-amino-2,3,5,6-tetramethylanilino)acetyl]-methylamino]piperidin-1-yl]methyl]benzamide. Grades: >98%. CAS No. 704869-38-5. Molecular formula: C26H37N5O2. Mole weight: 451.615. | |
| Sunitinib | Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Uses: Angiogenesis inhibitors; antineoplastic agents. Alternative Names: SU11248; SU 11248; SU-11248. Grades: >98%. CAS No. 557795-19-4. Molecular formula: C22H27FN4O2. Mole weight: 398.47. | |
| Sunitinib acid | Sunitinib acid. CAS No. 356068-93-4. | |
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