BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Pimavanserin tartrate | Pimavanserin is a potent and selective serotonin 5-HT2A inverse agonist. It has been used as an atypical antipsychotic in the treatment of psychosis associated with Parkinson's disease. Uses: Antiparkinson agents. Alternative Names: ACP-103; Nuplazid1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea tartrate. CAS No. 706782-28-7. Molecular formula: C50H68F2N6O4·C4H6O6. Mole weight: 1005.2. |  |
| Pimobendan | Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Uses: Phosphodiesterase inhibitors. Alternative Names: Alprostadil;UD-CG115; UD CG115; UD-CG 115; UD-CG-115; Pimobendan; pimobendane. Trade name: Vetmedin and Acardi. Grades: >98%. CAS No. 74150-27-9. Molecular formula: C19H18N4O2. Mole weight: 334.37. | |
| Pimonidazole | Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment. Alternative Names: NSC 380540; NSC-380540; NSC380540; PD 126675; PD126675; PD-126675; Ro 03-8799. Grades: 98%. CAS No. 70132-50-2. Molecular formula: C11H18N4O3. Mole weight: 254.29. | |
| Pimpinellin | Pimpinellin, isolated from the fruits of Psoralea corylifolia L., is a GABA receptor antagonist. Uses: Phytoalexin. Alternative Names: 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one. Grades: 95%. CAS No. 131-12-4. Molecular formula: C13H10O5. Mole weight: 246.2. | |
| Pinobanksin 3-acetate | Pinobanksin 3-acetate. CAS No. 52117-69-8. | |
| Pinobanksin 5-methyl ether | Pinobanksin 5-methyl ether is purified from Chinese propolis. Pinobanksin 5-methyl ether can induce detoxification genes. Alternative Names: (2R,3R)-3,7-dihydroxy-5-methoxy-2-phenyl-2,3-dihydrochromen-4-one. Grades: 99.0%. CAS No. 119309-36-3. Molecular formula: C16H14O5. Mole weight: 286.27. | |
| Pinocembrin 7-acetate | Pinocembrin 7-acetate isolated from the herbs of Pinus armandii. Uses: Antitumor activity. Alternative Names: (2S)-5-Hydroxy-4-oxo-2-phenyl-3,4-dihydro-2H-chromen-7-yl acetate. Grades: 95.0%. CAS No. 109592-60-1. Molecular formula: C17H14O5. Mole weight: 298.3. | |
| Pinocembrin chalcone | Pinocembrin chalcone is extracted from the rhizomes of Boesenbergia pandurata. It inhibits tyrosinase activity. It also inhibits the first step of enzymatic activation of heterocyclic amines and displays antimutagenic effect. It has antimicrobial activity against the antibiotic susceptible NG strain WHO V. It also shows activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL. Alternative Names: 2',4',6'-Trihydroxychalcone. Grades: 98.0%. CAS No. 4197-97-1. Molecular formula: C15H12O4. Mole weight: 256.25. | |
| Pinostrobin | Pinostrobin, which can be extracted from the herbs of Cajanus cajan, may be responsible for the anti-hemorrhagic and analgesic activity (peripheral analgesic activity) of Renealmia alpinia. It leads to depolarisation of the cell potential of endothelial cells. Pinostrobin was able to exert a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis. Besides, Pinostrobin (50mg/kg / dose) possesses definite therapeutical effect in the development of lesion score. Uses: Anti-hemorrhagic / analgesic. Alternative Names: Pinostrobin;5-Hydroxy-7-methoxyflavanone;75291-74-6;5-hydroxy-7-methoxy-2-phenylchroman-4-one;480-37-5;(+/-)-Pinostrobin;5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one;(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone;2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one;()-Pinostrobin;( inverted exclamation markA)-Pinostrobin;CHEMBL210800;SCHEMBL1485747;(2R)-5-hydroxy-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one;BCP09997;LMPK12140216;MFCD00017481;AKOS016009493;DB-051500;(+/-)-Pinostrobin, >=99.0% (TLC);NS00074278. Grades: >98%. CAS No. 480-37-5. Molecular formula: C16H14O4. Mole weight: 270.28. | |
| Piperlotine C | Piperlotine C is isolated from the herbs of Piper nigrum L. Alternative Names: 2-Propen-1-one, 1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-, (2E). Grades: 0.975. CAS No. 886989-88-4. Molecular formula: C16H21NO4. Mole weight: 291.4. | |
| Piperlotine D | Piperlotine D is isolated from the herbs of Piper nigrum L. Uses: Antiplatelet aggregation. Alternative Names: (2Z)-1-(1-Pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one. Grades: > 95%. CAS No. 958296-13-4. Molecular formula: C16H21NO4. Mole weight: 291.4. | |
| Piperoxane hydrochloride | Piperoxan is an antihistamine drug which is derived from benzodioxan. At first it was investigated by Fourneau as an α-adrenergic-blocking agent, then they found it resistant to histamine-induced bronchospasm in guinea pigs. Uses: Piperoxan is an antihistamine drug. Alternative Names: 1-((2,3-Dihydro-1,4-benzodioxin-2-yl)methyl)piperidinium chloride; Piperoxan HCl; F 933 hydrochloride; F933; F-933; F 933; Piperoxane hydrochloride; benodaine. Grades: ≥98%. CAS No. 135-87-5. Molecular formula: C14H20ClNO2. Mole weight: 269.769. | |
| Pirenzepine hydrochloride | Pirenzepine hydrochloride is an antiulcerative that acts via suppressing gastric secretion. Pirenzepine is a selective muscarinic M1 receptor antagonist. Uses: M1 muscarinic receptor selective antagonist. Alternative Names: Pirenzepine dihydrochloride; Pirenzepine HCl; Bisvanil; 11-[2-(4-methylpiperazin-1-yl)acetyl]-5-H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride. Grades: >98%. CAS No. 29868-97-1. Molecular formula: C19H23Cl2N5O2. Mole weight: 424.33. | |
| Pirfenidone | Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Alternative Names: S-7701; S 7701; S7701; AMR69; AMR-69; AMR 69; Pirespa; Pirfenex; Deskar, Esbriet; Etuary. Grades: >98%. CAS No. 53179-13-8. Molecular formula: C12H11NO. Mole weight: 185.22. | |
| Pirfenidone-[d5] | Pirfenidone-[d5] is the labelled analogue of Pirfenidone, which is an inhibitor for TGF-β production and TGF-β stimulated collagen production with anti-fibrotic and anti-inflammatory properties. Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis. Alternative Names: Pirfenidone-d5; 5-Methyl-N-phenyl-2-1H-pyridone-d5. Grades: 95% by HPLC; 95% atom D. CAS No. 1020719-62-3. Molecular formula: C12H6D5NO. Mole weight: 190.25. | |
| PJ34 | PJ34 is a novel and potential PARP inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP-1 (IC(50) = 20 nM). Alternative Names: PJ34; PJ-34; PJ 34. CAS No. 344458-15-7. Molecular formula: C17H18ClN3O2. Mole weight: 331.8. | |
| PKC-Theta Inhibitor | PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Alternative Names: CHEMBL248183; N4-((4-(Aminomethyl)Cyclohexyl)Methyl)-5-Nitro-N2-(2-(Trifluoromethoxy)Benzyl)Pyrimidine-2,4-Diamine; VC-8650; SCHEMBL3953579. Grades: 98%. CAS No. 736048-65-0. Molecular formula: C20H25F3N6O3. Mole weight: 454.4. | |
| PKG Drug G1 | PKG drug G1 is an activator of protein kinase GIα (PKGIα). It induces vasodilation and blood pressure reduction through the C42 PKG Iα independent mechanism. Alternative Names: Thiourea Deriv. 8; BDBM6641; CHEMBL141962; ZPA70378; HY-112197. Grades: 98%. CAS No. 374703-78-3. Molecular formula: C13H11N3OS. Mole weight: 257.31. | |
| Pleconaril | Pleconaril is a capsid function inhibitor which targets a conserved hydrophobic pocket of a major viral capsid protein called VP-1. Pleconaril inhibits attachment and virus uncoating. Uses: Picornavirus replication inhibitor. antiviral. Alternative Names: SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843; Pleconaril, Picovir. 3-[3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazolePicovirpleconaril. Grades: 0.9996. CAS No. 153168-05-9. Molecular formula: C18H18F3N3O3. Mole weight: 381.35. | |
| Plerixafor Impurity I | An impurity of Plerixafor which is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. Alternative Names: N-(4-Hydroxymethylbenzyl) Cyclam; 4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)-Benzenemethanol. Grades: > 95%. CAS No. 176252-20-3. Molecular formula: C18H32N4O. Mole weight: 320.48. | |
| Plerixafor Impurity III | Plerixafor Impurity III is an impurity of Plerixafor, an immunostimulant indicated in combination with G-CSF to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with NHL and MM. Alternative Names: 1,11-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane. CAS No. 771464-86-9. Molecular formula: C46H84N12. Mole weight: 805.24. | |
| Pluripotin | SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo. Uses: Self-renewal. Alternative Names: SC-1; SC 1; SC1; Pluripotin. Grades: 0.98. CAS No. 839707-37-8. Molecular formula: C27H25F3N8O2. Mole weight: 550.54. | |
| PLX51107 | PLX51107 is a potent and selective BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2). It blocks the interaction mediated by the four BET family proteins. Alternative Names: (S)-4-(6-(3,5-dimethylisoxazol-4-yl)-1-(1-(pyridin-2-yl)ethyl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid; PLX 51107; PLX-51107. CAS No. 1627929-55-8. Molecular formula: C26H22N4O3. Mole weight: 438.48. | |
| PLX-647 | PLX-647 is PLX647 is a potent inhibitors of both FMS and KIT that show strong selectivity compared with other kinases. In the in vitro enzymatic assay, PLX647 inhibits FMS with IC50 = 0.028μM and KIT with IC50 = 0.016 μM. PLX647 represents a unique class of kinase inhibitors with unique dual FMS and KIT specificity. Alternative Names: PLX-647; PLX 647; PLX647. Grades: 0.98. CAS No. 873786-09-5. Molecular formula: C21H17F3N4. Mole weight: 382.39. | |
| PMPA sodium salt | PMPA is an inhibitor of glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase / NAALADase). Alternative Names: PMPA tetrasodium. CAS No. 373645-42-2. Molecular formula: C6H7Na4O7P. Mole weight: 314.05. | |
| PND-1186 (VS-4718) | PND-1186 (VS-4718) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. Phase 1. Alternative Names: PND1186; PND 1186; PND1186; SR 2516; SR2516; SR2516; VS4718; VS4718; VS 4718. Grades: >98%. CAS No. 1061353-68-1. Molecular formula: C25H26F3N5O3. Mole weight: 501.5. | |
| p-Nitro-m-phenylenediamine sulfate | p-Nitro-m-phenylenediamine sulfate. Alternative Names: 4-Nitrobenzene-1,3-diamine sulfate; 4-Nitro-1,3-phenylenediamine sulfate; 4-Nitro-m-phenylenediamine sulfate; 1,3-Benzenediamine, 4-nitro-, sulfate (1:1). Grades: 98%. CAS No. 200295-57-4. Molecular formula: C6H9N3O6S. Mole weight: 251.21. | |
| PNU-140155 | PNU-140155. CAS No. 333753-67-6. | |
| PNU159682-EDA | PNU159682-EDA is a drug-linker conjugate for ADC by using PNU159682 (a potent DNA topoisomerase II inhibitor), linked via EDA. Alternative Names: EDA-PNU-159682; PNU-EDA. Grades: 90%. CAS No. 2255344-14-8. Molecular formula: C33H39N3O12. Mole weight: 669.68. | |
| PNU-282987 hydrochloride | PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). Alternative Names: PNU-282987; PNU 282987; PNU282987; Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-. Grades: >98%. CAS No. 123464-89-1. Molecular formula: C14H18Cl2N2O. Mole weight: 301.21. | |
| Polmacoxib | Polmacoxib is a first-in-class NSAID drug candidate that acts as a dual inhibitor of COX-2 and carbonic anhydrase (CA). It exhibits superior safety for cardiovascular, renal, and gastrointestinal tissues due to its dual COX-2 and CA binding properties. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Alternative Names: CG100649; CG-100649; CG 100649; polmacoxib; 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide. Grades: > 98%. CAS No. 301692-76-2. Molecular formula: C18H16FNO4S. Mole weight: 361.387. | |
| Poly[2,1,3-benzothiadiazole-4,7-diyl(9,9-dioctyl-9H-fluorene-2,7-diyl)] | F8BT can be used with poly(9,9-di-n-octylfluorenyl-2,7-diyl) (PTO) to map the effect of noise sources on photoconducting charge transports by evaluating the conductivity and noise source density (Nt). It may also form a nanocomposite with single walled carbon nanotube (SWCNT) with excellent electric properties and high Seebeck coefficient, for potential application in the development of photovoltaic power and biomass energy. Organic light emitting diode (OLED) devices can be fabricated by depositing a blend of F8 and F8BT on PEDOT:PSS films. Alternative Names: F8BT; PFBT; Poly(9,9-dioctylfluorene-alt-benzothiadiazole). CAS No. 210347-52-7. Molecular formula: (C35H42N2S)n. | |
| Polyester fibers | Polyester fibers. CAS No. 80595-68-2. | |
| Polygalasaponin XXXII | Polygalasaponin XXXII. CAS No. 176182-04-0. | |
| Polygonal | Polygonal isolated from the roots of Polygonum hydropiper. Alternative Names: 3,4,4aα,5,6,7,8,8a-Octahydro-3α-hydroxy-5,5,8aβ-trimethyl-2-naphthalenecarbaldehyde; (3R,4aS,8aR)-3-Hydroxy-5,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahyd ro-2-naphthalenecarbaldehyde. Grades: 97.5%. CAS No. 72537-20-3. Molecular formula: C14H22O2. Mole weight: 222.3. | |
| Polyporusterone A | Polyporusterone A is a steroid isolated from Polyporus umbellatus (zhu ling). CAS No. 141360-88-5. Molecular formula: C28H46O6. Mole weight: 478.67. | |
| Polysulfated Glycosaminoglycan | Polysulfated Glycosaminoglycan. CAS No. 64082-61-7. | |
| (±)-Pomalidomide-[d3] (phthalimide-[4,5,6-d3]) | One of the isotopic labelled form of (±)-Pomalidomide, which is a potent TNF-α production inhibitor and could probably used as an antitumor agent. Alternative Names: 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione-5,6,7-d3; CC-4047-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 2093128-28-8. Molecular formula: C13H8D3N3O4. Mole weight: 276.27. | |
| Pomalidomide-PEG1-azide | Pomalidomide-PEG1-azide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Alternative Names: Pomalidomide-NH-PEG1-N3; 2-(2-Azidoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide. Grades: ≥98%. CAS No. 2133360-04-8. Molecular formula: C17H16N6O6. Mole weight: 400.35. | |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Alternative Names: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. Grades: ≥98%. CAS No. 2139348-63-1. Molecular formula: C26H35N3O11. Mole weight: 565.57. | |
| Pomolic acid | Pomolic acid is a captivating natural compound, boasting intriguing prospects in the esteemed biomedical research of afflictions, encompassing the domains of cancer, neurodegenerative infirmities and cardiovascular incongruities. Alternative Names: 3β,19-Dihydroxy-5α-urs-12-en-28-oic acid;3β,19-Dihydroxyurs-12-en-28-oic acid;3β,19α-Dihydroxyurs-12-ene-28-oic acid;Benthamic acid;Urs-12-en-28-oic acid, 3,19-dihydroxy-, (3β)-;Randialic acid A. CAS No. 13849-91-7. Molecular formula: C30H48O4. Mole weight: 472.71. | |
| Ponatinib | Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively. Alternative Names: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534; AP-24534; AP 24534; Ponatinib Brand name: Iclusig. Grades: >98%. CAS No. 943319-70-8. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented the increase in paw volume and joint inflammation in rats with adjuvant-induced arthritis. It reduces both the amount of circulating peripheral lymphocytes and the infiltration of lymphocytes into target tissues by preventing egress of lymphocytes. It was developed by Actelion. It is in Clinical stage three. Uses: Ponesimod acts as a functional antagonist. it has potential immunomodulating activity. it may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. it is also an experimental drug for the treatment of multiple sclerosis (ms) and psoriasis. Alternative Names: ACT-128800; ACT 128800; ACT128800; Ponvory; (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one. Gra | |
| Ponicidin | Ponicidin is a natural diterpenoid compound found in the herbs of Isodon japonicus. Ponicidin shows immunoregulatory and anti-inflammatory functions. Ponicidin also exhibits the activities of anti-viral, anti-leukemi and anti-cancer. Alternative Names: Rubescensin B. Grades: >98%. CAS No. 52617-37-5. Molecular formula: C20H26O6. Mole weight: 362.42. | |
| Posaconazole-[d5] | Posaconazole-[d5], is the labelled analogue of Posaconazole, which is a sterol C14α demethylase inhibitor with an IC50 of 0.25 nM. Posaconazole is a triazole antifungal medication. Alternative Names: Posaconazole D5. Grades: > 95%. CAS No. 1217785-83-5. Molecular formula: C37H37D5F2N8O4. Mole weight: 705.8. | |
| Posaconazole Diastereoisomer Related Compound 1 | Posaconazole Diastereoisomer Related Compound 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Alternative Names: (5R-trans)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester; 1,4-Anhydro-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol. Grades: > 95%. CAS No. 159811-30-0. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 2 | Posaconazole Diastereoisomer Related Compound 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Alternative Names: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; D-erythro-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-. Grades: > 95%. CAS No. 166583-12-6. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 5 | Posaconazole Diastereoisomer Related Compound 5 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Alternative Names: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-L-threo-pentitol. Grades: > 95%. CAS No. 149809-42-7. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Impurity 33 Oxalate | Posaconazole Impurity 33 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Alternative Names: N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide oxalate; 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde Oxalate. Grades: >95%. CAS No. 1887197-42-3. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34. | |
| Posaconazole Impurity 4 | Posaconazole Impurity 4 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Alternative Names: D-Threo-Pentitol; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: >95%. CAS No. 160709-02-4. Molecular formula: C14H15F2N3O2. Mole weight: 295.28. | |
| Potassium (4-methoxy)benzyloxymethyltrifluoroborate | Alkoxymethyltrifluoroborate undergoes palladium-catalyzed carbon-carbon bond formation (Suzuki-Miyuara reaction) with aryl chlorides to provide a non-traditional disconnection for the preparation of aryl- and heteroaryl ethers. Alternative Names: Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate. Grades: 95 %. CAS No. 1027642-26-7. Molecular formula: C9H11BF3KO2. Mole weight: 258.087. | |
| Potassium (Bromomethyl)trifluoroborate | Organotrifluoroborate involved in: Suzuki-Miyaura cross-coupling reactions; Synthesis of functionalized ethyltrifluoroborates; SN2 displacement with alkoxidesOrganotrifluoroborates as versatile and stable boronic acid surrogates; Versatile starting material for preparation of a variety of functionalized substrates for Suzuki coupling. Alternative Names: Potassium bromomethyltrifluoroborate. Grades: 90%. CAS No. 888711-44-2. Molecular formula: CH2BrF3BK. Mole weight: 200.84. | |
| PP2 | PP2 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 4 nM), p59fynT (IC50 = 5 nM), Hck (IC50 = 5 nM), and Src (IC50 = 100 nM). Alternative Names: PP-2; PP 2; AG 1879; AG-1879; AG1879. CAS No. 172889-27-9. Molecular formula: C15H16ClN5. Mole weight: 301.77. | |
| PP242 | PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM. PP242 also shows residual (micromolar) activity against panel of tyrosine kinases. But PP242 was much less active against other PI3K family members with IC50 of 2, 2.2, 0.1, 1.3 and 0.41 μM for p110α, p110β, p110δ, p110γ and DNA-PK, respectively. Alternative Names: PP 242; PP-242; Torkinib. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.345. | |
| PPACK hydrochloride | PPACK hydrochloride. CAS No. 142036-63-3. | |
| PR-39 TFA | PR 39 TFA is a gene-encoded, proline-arginine-rich porcine antimicrobial peptide with multiple biological functions. It might function in the inflammatory milieu not only to kill bacteria, but also to aid in modulating the viability of inflammatory cells by regulating apoptosis. Grades: 98%. Molecular formula: C231H347F3N70O42. Mole weight: 4833.76. | |
| Pracinostat | Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors. Alternative Names: SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat. Grades: >98%. CAS No. 929016-96-6. Molecular formula: C20H30N4O2. Mole weight: 358.486. | |
| (-)-Praeruptorin B | (-)-Praeruptorin B is a natural coumarin compound found in some plant. Alternative Names: (-)-Anomalin; (9R)-2-Oxo-8,8-dimethyl-9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-9α,10α-diol 9,10-bis[(Z)-2-methyl-2-butenoate]; 9,10-Dihydro-8,8-dimethyl-9α,10α-bis[(Z)-1-oxo-2-methyl-2-butenyloxy]-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one. Grades: >95%. CAS No. 4970-26-7. Molecular formula: C24H26O7. Mole weight: 426.465. | |
| Pralatrexate | Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Uses: Aminopterin/ analogs & derivatives; folic acid antagonists. Alternative Names: Pralatrexate;Folotyn; 10-Propargyl-10-deazaaminopterin; HSDB 7786; pralatrexato; pralatrexatum; PDX; CHEBI:71223; NSC-754230; UNII-A8Q8I19Q20; Pralatrexate(Folotyn); DTXSID3048578; A8Q8I19Q20; (2S)-2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioic acid; N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-; DTXCID3028504; 146464-95-1 (racemic); NSC754230; NSC 754230; (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid; NCGC00242596-01; (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid. Grades:>98%. CAS No. 146464-95-1. Molecular formula: C23H23N7O5. Mole weight: 477.47. | |
| Pramipexole EP Impurity B | An impurity of Pramipexole, which is a thiazole derivative usually used as a D2-receptor agonist. Uses: Pramipexole derivative. Alternative Names: N-Propylpramipexole; 2-N-Propyl Pramipexole; (S)-4,5,6,7-Tetrahydro-N2-propyl-N6-propyl-2,6-benzothiazolediamine; (S)-N2,N6-dipropyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine. Grades: 95%. CAS No. 1246815-83-7. Molecular formula: C13H23N3S. Mole weight: 253.41. | |
| Pramipexole Impurity E | An impurity of Pramipexole which is a thiazole derivative usually used as a D2-receptor agonist. Alternative Names: N-(2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)propionamide; (S)-Pramipexole Amide Pramipexole related compound B; Pramipexole EP lmpurity E; Pramipexole USP Related Compound E. Grades: >95%. CAS No. 106006-84-2. Molecular formula: C10H15N3OS. Mole weight: 225.31. | |
| Pranidipine | Pranidipine is a long acting calcium channel antagonist that can be used as a cardiovascular agent. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(2E)-3-phenyl-2-propen-1-yl] Ester; FRC 8411; OPC 13340. Grades: 95%. CAS No. 99522-79-9. Molecular formula: C25H24N2O6. Mole weight: 448.473. | |
| Pranoprofen | Pranoprofen (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM. Alternative Names: Pyranoprofen. Grades: >98%. CAS No. 52549-17-4. Molecular formula: C15H13NO3. Mole weight: 255.27. | |
| Prasugrel EP Impurity G | Prasugrel EP Impurity G is an impurity of Prasugrel, which is a platelet inhibitor used to prevent formation of blood clots. Alternative Names: Cyclopropyl 2-Fluorophenyl Diketone; 2-Fluorophenyl Cyclopropyl Diketone; 1,2-Ethanedione, 1-cyclopropyl-2-(2-fluorophenyl)-; 1-Cyclopropyl-2-(2-fluorophenyl)-1,2-ethanedione; Prasugrel diketone. Grades: ≥95%. CAS No. 1391054-37-7. Molecular formula: C11H9FO2. Mole weight: 192.19. | |
| Pratensein | Pratensein is found in he herbs of Trifolium pratense L. Alternative Names: 3'-hydroxybiochanin A; 5,7,3'-trihydroxy-4'-methoxyisoflavone. Grades: > 95%. CAS No. 2284-31-3. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Prazosin-[d8] | An isotope labelled Prazosin. Prazosin is an inverse agonist at alpha-1 adrenergic receptor. Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD). Alternative Names: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8; Furazosin-d8; Lentopres-d8; NSC 292810-d8; Peripress-d8. Grades: >95%. CAS No. 1006717-55-0. Molecular formula: C19H13D8N5O4. Mole weight: 391.46. | |
| PRE-084 | PRE-084 Hydrochloride is a selective sigma-1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). PRE-084 is selective for PCP receptors (IC50 > 100000 nM) and several other receptor systems. It exhibits neuroprotective property. Alternative Names: 2-(4-Morpholinyl)ethyl 1-phenylcyclohexanecarboxylate hydrochloride; PRE-084 (hydrochloride); PRE 084 (hydrochloride); PRE084 (hydrochloride). Grades: 98%. CAS No. 138847-85-5. Molecular formula: C19H27NO3. Mole weight: 317.4. | |
| pre-Alfacalcidol PTAD Adduct | pre-Alfacalcidol PTAD Adduct is an impurity of alfacalcidol, which is one of the synthetic analog of Vitamin D3 being effective in mediating intestinal calcium absorbtion and bone calcium metabolism. Alternative Names: triazoline adduct of pre-alfacalcidol. Molecular formula: C35H49N3O4. Mole weight: 575.794. | |
| Prednisolone Tebutate | Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant. Alternative Names: 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(3,3-Dimethylbutyrate); 3,3-Dimethylbutyric Acid 21-Ester with 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione; 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(3,3-dimethylbutyrate); Codelcortone TBA; Hydeltra TBA; Predalone TBA; Prednisolone 21-tert-Butylacetate; Prednisolone TBA; Prednisolone Tebutate; Prednisolone tert-Butylacetate. Grades: ≥95%. CAS No. 7681-14-3. Molecular formula: C27H38O6. Mole weight: 458.59. | |
| Pregn-5-ene-3β,17α,20S-triol | Pregn-5-ene-3β,17α,20S-triol is a metabolite of Pregnenolone. Alternative Names: (3β,17α,20S)-Pregn-5-ene-3,17,20-triol; delta 5-Pregnenetriol. Grades: 98.0%. CAS No. 903-67-3. Molecular formula: C21H34O3. Mole weight: 334.5. | |
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