BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| P7C3 | P7C3 is a proneurogenic and neuroprotective agent that activates NAMPT. P7C3 protects neurons from apoptosis and promotes neurogenesis in mice. It also improves cognitive function and memory in aged mice. Alternative Names: 1-Anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol; 1-(3,6-Dibromo-carbazol-9-yl)-3-phenylamino-propan-2-ol; 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; 1-(3,6-dibromocarbazol-9-yl)-3-(phenylamino)propan-2-ol. Grades: >98%. CAS No. 301353-96-8. Molecular formula: C21H18Br2N2O. Mole weight: 474.196. |  |
| P7C3-A20 | P7C3-A20, an analogue of P7C3, is a neuroprotective compound which inhibits mature neuronal cell death while also increasing the net magnitude of postnatal neurogenesis in models of neurodegeneration and acute injury. Alternative Names: N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline; P7C-3A20; P7C3A20; P7C 3A20. CAS No. 1235481-90-9. Molecular formula: C22H19Br2FN2O. Mole weight: 506.21. | |
| Pachyaximine A | Pachyaximine A, isolated from the herbs of Pachysandra axillaris, possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. Uses: Antibacterial; antimicrobial. Alternative Names: Alkaloid-C; (-)-Pachyaximine A; Pregn-5-en-20-amine,3-Methoxy-N,N-diMethyl-, (3b,20S)- (9CI); (3β,20S)-3-Methoxy-N,N-dimethylpregn-5-en-20-amine. Grades: > 95%. CAS No. 128255-08-3. Molecular formula: C24H41NO. Mole weight: 359.6. | |
| Palbociclib Impurity 002 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C14H21BrN4. Mole weight: 325.25. | |
| Palbociclib Impurity 022 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; 1779124-68-3; tert-Butyl4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; SCHEMBL17550837; CS-0448403; EN300-7455913. Grades: 95%. CAS No. 1779124-68-3. Molecular formula: C14H20N4O4. Mole weight: 308.33. | |
| Palbociclib Impurity 025 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: N-Formyl Palbociclib; Palbociclib Impurity F; Palbociclib N-Aldehyde; Palbociclib N-Formyl Impurity. Grades: 95%. CAS No. 2174002-16-3. Molecular formula: C25H29N7O3. Mole weight: 475.54. | |
| Palbociclib Impurity 027 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C27H35N7O2. Mole weight: 489.61. | |
| Palbociclib Impurity 028 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C18H24N4O. Mole weight: 312.41. | |
| Palbociclib Impurity 029 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: 1-(2-nitropyridin-3-yl)piperazine; 1566082-34-5; GS0805; EN300-2138375. Grades: 95%. CAS No. 1566082-34-5. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 030 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: 1-(4-nitropyridin-3-yl)piperazine; GS0814; 1211541-02-4. Grades: 95%. CAS No. 1211541-02-4. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 10 | Palbociclib Impurity 10 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Alternative Names: 1-Piperazinecarboxylic acid, 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis-, 1,1'-bis(1,1-dimethylethyl) ester; 1,1'-Bis(1,1-dimethylethyl) 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis[1-piperazinecarboxylate]; Bis(2-methyl-2-propanyl) 4,4'-[(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]di(1-piperazinecarboxylate). Grades: 95%. CAS No. 2206135-30-8. Molecular formula: C41H55N11O5. Mole weight: 781.94. | |
| Palbociclib Impurity 2 | Palbociclib Impurity 2 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Alternative Names: Desoxo-palbociclib; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 8-Cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity D. Grades: 95%. CAS No. 2204863-06-7. Molecular formula: C24H29N7O. Mole weight: 431.53. | |
| Palbociclib Impurity 4 | An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Alternative Names: Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-(1-hydroxyethyl)-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-. Grades: > 95%. CAS No. 1376615-91-6. Molecular formula: C24H31N7O2. Mole weight: 449.56. | |
| Palbociclib Impurity F | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Grades: 95%. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35. | |
| Palbociclib Isethionate | Palbociclib is a potent Cdk4/6 inhibitor. Alternative Names: PD 0332991 Isethionate; PD0332991 Isethionate; PD-0332991 Isethionate; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one isethionate. Grades: >98%. CAS No. 827022-33-3. Molecular formula: C26H35N7O6S. Mole weight: 573.66. | |
| Palbociclib N-oxide Hydrochloride | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Alternative Names: PD-0332991 hydrochloride; 1-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide Hydrochloride salt. Molecular formula: C24H30ClN7O3. Mole weight: 499.99. | |
| Palbociclib Pyridine N-Oxide | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. CAS No. 2098673-40-4. Molecular formula: C24H29N7O3. Mole weight: 463.54. | |
| Palifosfamide | Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Alternative Names: Isophosphamide mustard; Isophosphoramide mustard; IPAM; bis(2-chloroethylamino)phosphinic acid. Grades: ≥ 98%. CAS No. 31645-39-3. Molecular formula: C4H11Cl2N2O2P. Mole weight: 221.018. | |
| Paliperidone-[d4] | Paliperidone-[d4] is the labelled analogue of Paliperidone, which is a metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: Paliperidone D4; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-d4]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 9-Hydroxyrisperidone-d4; R 76477-d4; Risperidone Impurity C (EP)-d4. Grades: ≥97%. CAS No. 1020719-55-4. Molecular formula: C23H23D4FN4O3. Mole weight: 430.52. | |
| Paliperidone N-Oxide | An impurirty of Risperidone. Risperidone is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: Paliperidone Related Compound D (USP); 9-Hydroxy Risperidone N-Oxide; 4-(6-fluorobenzo[d]isoxazol-3-yl)-1-(2-(9-hydroxy-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl)piperidine 1-oxide. Grades: 95%. CAS No. 761460-08-6. Molecular formula: C23H27FN4O4. Mole weight: 442.49. | |
| Paliperidone Palmitate | An impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Alternative Names: 9-Hydroxyrisperidone Palmitate; Invega Sustenna; RO 92670; Hexadecanoic Acid 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Ester. Grades: > 95%. CAS No. 199739-10-1. Molecular formula: C39H57FN4O4. Mole weight: 664.91. | |
| Paliperidone Palmitate N-Oxide | A metabolite of Paliperidone Palmitate, an impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Alternative Names: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Hexadecanoate; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Ester Hexadecanoic Acid. CAS No. 1404053-60-6. Molecular formula: C39H57FN4O5. Mole weight: 680.89. | |
| Palmatrubine | Palmatrubine is an alkaloid isolated from the herbs of Tinospora sagittata. Alternative Names: Dibenzo[a,g]quinolizinium, 5,6-dihydro-9-hydroxy-2,3,10-trimethoxy-. Grades: >98%. CAS No. 16176-68-4. Molecular formula: C20H20NO4. Mole weight: 338.4. | |
| Palonosetron N-Oxide | An impurity of Palonosetron which is used for preventing nausea and vomiting caused by cancer chemotherapy. Alternative Names: Palonosetron N-Oxide; (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one N-Oxide. Grades: > 95%. CAS No. 813425-83-1. Molecular formula: C19H24N2O2. Mole weight: 312.45. | |
| Palosuran | Palosuran is a new Urotensin-II receptor antagonist (IC50=3.6±0.2 nM). Uses: Urotensin-ii receptor antagonist. Alternative Names: 1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(2-methylquinolin-4-yl)urea;ACT-058362; ACT058362; ACT 058362. Grades: ≥95%. CAS No. 540769-28-6. Molecular formula: C25H30N4O2. Mole weight: 418.54. | |
| Pamiparib | Pamiparib is a potent and selective inhibitor of PARP1/PARP2 displaying anticancer activity. Uses: Poly(adp-ribose) polymerase inhibitors. Alternative Names: BGB-290. CAS No. 1446261-44-4. Molecular formula: C16H15FN4O. Mole weight: 298.31. | |
| Panaxadiol | Panaxadiol, a triterpenoid compound extracted from roots of Panax ginseng C, a novel antitumor agent that regulates of cell cycle transition and induces apoptotic cells. Inhibites DNA synthesis in a dose-dependent manner (in SK-HEP-1 cells and HeLa cells: Alternative Names: (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol panaxadiol panaxadiol, (3beta,12beta)-isomer. Grades: >98%. CAS No. 19666-76-3. Molecular formula: C30H52O3. Mole weight: 460.73. | |
| Panaxatriol | Panaxatriol, a natural product extracted from the roots of Panax ginseng C. A. Mey, with significant antiradiation effects it can relieve myelosuppression induced by radiation injury. It ameliorates I/R-induced myocardial damage by reducing oxidative stre. Alternative Names: Dammarane-3,6,12-triol, 20,25-epoxy-,(3β,6β,12β,20R)-;Panoxatriol;(20R)-20,25-Epoxy-5α-dammarane-3β,6α,12β-triol;panaxatriol, (3beta,6alpha,12beta)-isomer. Grades: >98%. CAS No. 32791-84-7. Molecular formula: C30H52O4. Mole weight: 476.73. | |
| Pangelin | Pangelin is found in the roots of Angelica dahurica. Alternative Names: R-(+)-Pangelin. Grades: > 95%. CAS No. 33783-80-1. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Paniculidine A | Paniculidine A is isolated from the herbs of Murraya exotica L. Alternative Names: 1H-Indole-3-butanoic acid,R-methyl-,methyl ester,(RR)-;1H-Indole-3-butanoic acid, α-methyl-, methyl ester, (αR)-. Grades: 97%. CAS No. 97399-93-4. Molecular formula: C14H17NO2. Mole weight: 231.3. | |
| Paniculidine B | Paniculidine B is isolated from the herbs of Murraya exotica L. Alternative Names: (2R)-4-(1-Methoxy-1H-indol-3-yl)-2-methyl-1-butanol. Grades: > 95%. CAS No. 97399-94-5. Molecular formula: C14H19NO2. Mole weight: 233.3. | |
| Paniculidine C | Paniculidine C is isolated from the herbs of Murraya exotica L. Alternative Names: (R)-2-Methyl-4-(1H-indole-3-yl)-1-butanol. CAS No. 97399-95-6. Molecular formula: C13H17NO. Mole weight: 203.3. | |
| Paniculoside I | Paniculoside I is isolated from the herbs of Stevia rebaudiana. Alternative Names: (4alpha,15beta)-15-Hydroxykaur-16-en-18-oic acid beta-D-glucopyranosyl ester; 1-O-[(5β,8α,9β,10α,13α,15β)-15-Hydroxy-18-oxokaur-16-en-18-yl]-β- D-glucopyranose. Grades: > 95%. CAS No. 60129-63-7. Molecular formula: C26H40O8. Mole weight: 480.6. | |
| Paniculoside II | Paniculoside II is a natural diterpenoid found in the herbs of Stevia rebaudiana. Alternative Names: (4R,15R)-11β,15-Dihydroxykaur-16-en-18-oic acid [β-D-glucopyranosyl] ester; Kaur-16-en-18-oic acid, 11,15-dihydroxy-, β-D-glucopyranosyl ester, (4α,11β,15β)-. Grades: >97%. CAS No. 60129-64-8. Molecular formula: C26H40O9. Mole weight: 496.59. | |
| Paniculoside III | Paniculoside III is a natural diterpenoid compound found in several plants. . Alternative Names: (4R)-11β-Hydroxy-15-oxokaur-16-en-18-oic acid β-D-glucopyranosyl ester. Grades: >95%. CAS No. 60129-65-9. Molecular formula: C26H38O9. Mole weight: 494.57. | |
| p-Anisil | p-Anisil is a reagent used in the preparation of novel quinoxaline derivatives with anti-HIV activity. Alternative Names: 4,4'-Dimethoxybenzil; Anisil. Grades: 95 %. CAS No. 1226-42-2. Molecular formula: C16H14O4. Mole weight: 270.28. | |
| Pantoprazole-[d6] | Pantoprazole-[d6] is the labelled analogue of Pantoprazole, which is a proton pump inhibitor used for short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD). Alternative Names: Pantoprazole D6. Grades: 95% by HPLC; 95% atom D. CAS No. 922727-65-9. Molecular formula: C16H9D6F2N3O4S. Mole weight: 389.40. | |
| Paracetamol EP Impurity L | An impurity of of Acetaminaphen, a medication used for the treatment of fever and mild to moderate pain. Alternative Names: 2-Hydroxy-4',5-diacetamido-diphenyl Ether; N-(4-(4-Acetamido-2-hydroxyphenoxy)phenyl)acetamide. CAS No. 2514961-29-4. Molecular formula: C16H16N2O4. Mole weight: 300.31. | |
| Paradol | Paradol(6-Paradol) is the active flavor constituent of the seeds of Guinea pepper (Aframomum melegueta); Paradol has been found to have antioxidative and antitumor promoting effects. Alternative Names: [6]-Gingerone; [6]-Paradol. Grades: >98%. CAS No. 27113-22-0. Molecular formula: C17H26O3. Mole weight: 278.39. | |
| Para Red-[d6] | Para Red-[d6] is an isotopic labelled red dye. Alternative Names: Para Red-d6; 3,4,5,6,7,8-hexadeuterio-1-[(4-nitrophenyl)diazenyl]naphthalen-2-ol. CAS No. 1014689-16-7. Molecular formula: C16H11N3O3. Mole weight: 299.31. | |
| Parecoxib Impurity 1 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Alternative Names: Valdecoxib Disulfonamide Impurity; Parecoxib Impurity H. Grades: 95%. CAS No. 1708094-99-8. Molecular formula: C22H23N3O7S2. Mole weight: 505.56. | |
| Parecoxib Impurity 24 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Alternative Names: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)isobutyramide; 2-methyl-N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide; Propanamide, 2-methyl-N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; SCHEMBL5069872; DTXSID50627261; AS-80624; CS-0255351; F83303; 2-Methyl-N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide; 2-Methyl-N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonyl]propanamide; 2-METHYL-N-[4-(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)BENZENESULFONYL]PROPANAMIDE; N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)isobutyramide (Palbociclib Impurity). Grades: 95%. CAS No. 198470-82-5. Molecular formula: C20H20N2O4S. Mole weight: 384.45. | |
| Paricalcitol Impurity 4 | Paricalcitol Impurity 4 is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Alternative Names: PRC-2; (1R,3aR,7aR)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-one. CAS No. 95716-68-0. Molecular formula: C19H32O2. Mole weight: 292.46. | |
| Paricalcitol Intermediate A | Paricalcitol Intermediate A is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Alternative Names: (2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)cyclohexylidene)ethyl)diphenylphosphine oxide; (3R-trans)-[2-[3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexylidene]ethyl]diphenyl-phosphine Oxide. CAS No. 139356-39-1. Molecular formula: C32H51O3PSi2. Mole weight: 570.90. | |
| Paricalcitol Intermediate CD | Paricalcitol Intermediate CD is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Alternative Names: (1R,3aR,7aR)-1-[(E,2R,5S)-5,6-dimethyl-6-trimethylsilyloxyhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-one. CAS No. 95716-69-1. Molecular formula: C22H40O2Si. Mole weight: 364.645. | |
| Parimifasor | Parimifasor is an immunomodulator that exhibits anti-inflammatory activity. It is a potential therapy for inflammatory bowel disease (IBD). Alternative Names: 3-chloro-N-[(3-chloro-5-fluoroanilino)-[[5-(trifluoromethyl)-1H-pyrazol-3-yl]amino]methylidene]benzamide. CAS No. 1796641-10-5. Molecular formula: C18H11Cl2F4N5O. Mole weight: 460.214. | |
| Paroxetine EP Impurity A HCl | An impurity of Paroxetine which is the first antidepressant to treat panic disorder formally approved in the United States. Alternative Names: Paroxetine EP Impurity A hydrochloride; Paroxetine HCl EP Impurity A; Desfluoro-Paroxetine HCl; Desfluoro-Paroxetine hydrochloride. Grades: > 95%. CAS No. 1394842-91-1. Molecular formula: C19H21NO3.HCl. Mole weight: 347.84. | |
| Paroxetine EP Impurity G | An impurity of Paroxetine, which is a selective serotonin reuptake inhibitor. Alternative Names: 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine; Pyridine, 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-. CAS No. 69675-10-1. Molecular formula: C12H14FN. Mole weight: 191.24. | |
| Paroxetine hydrochloride | Paroxetineis a selective serotonin reuptake inhibitor (SSRI). It is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms. Uses: Cytochrome p-450 cyp2d6 inhibitors. Alternative Names: Win 47203; Win-47203; Win47203. Grades: >98%. CAS No. 78246-49-8. Molecular formula: C19H21ClFNO3. Mole weight: 365.83. | |
| Paroxetine Impurity G HCl | An impurity of Paroxetine which is an antidepressant to treat diseases like depression, obsessive-compulsive disorder, anxiety disorders. Alternative Names: 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride; 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine Hydrochloride; 1-Methyl-4-(4'-fluorophenyl)-1,2,3,6-tetrahydropyridine Hydrochloride; Paroxetine EP Impurity G. Grades: > 95%. CAS No. 1012886-75-7. Molecular formula: C12H14FN.HCl. Mole weight: 227.71. | |
| Paulownin | Paulownin isolated from the barks of Paulownia tomentosa. It can highly inhibit the growth of H. pylori and H. pylori related to E. coli. Alternative Names: (1S,6aβ)-1β,4β-Bis(1,3-benzodioxole-5-yl)-tetrahydro-1H,3H-furo[3,4-c]furan-3aβ-ol; (3R,3aS,6S,6aR)-3,6-bis(1,3-benzodioxol-5-yl)-3,4,6,6a-tetrahydro-1H-furo[3,4-c]furan-3a-ol. Grades: 98.5%. CAS No. 13040-46-5. Molecular formula: C20H18O7. Mole weight: 370.4. | |
| Paxiphylline D | Paxiphylline D is an alkaloid isolated from the herbs of Daphniphyllum paxianum. Alternative Names: Methyl (1R,2S,3R,5R,6S,8R,10S)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icosa-13(19),16-diene-17-carboxylate 8-oxide. Grades: 97%. CAS No. 1092555-02-6. Molecular formula: C23H29NO4. Mole weight: 383.5. | |
| Pazopanib | Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. Uses: Anticancer reagents. Alternative Names: GW786034; GW786034; GW 786034; Pazopanib; US brand name: Votrient. Grades: >98%. CAS No. 444731-52-6. Molecular formula: C21H23N7O2S. Mole weight: 437.52. | |
| PBK-IN-9 | PBK-IN-9. CAS No. 1338540-55-8. | |
| PD0325901 | PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine / tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. Uses: Reprogramming, self-renewal. Alternative Names: PD 0325901; PD 325901. Grades: >98%. CAS No. 391210-10-9. Molecular formula: C16H14F3IN2O4. Mole weight: 482.198. | |
| PD123319 | PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. Uses: Vasoconstrictor agents. Alternative Names: PD123319; PD 123319; PD-123319; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-(+)-PD 123319; PD 123319. Grades: >98%. CAS No. 130663-39-7. Molecular formula: C31H32N4O3. Mole weight: 508.61. | |
| PD173074 | PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a therapeutic modality using eight UC cell lines. PD173074 suppressed cell proliferation remarkably in two cell lines, namely, UM-UC-14 and MGHU3, which expressed mutated FGFR3 protein. Cell cycle analysis revealed the growth inhibitory effect of PD173074 was associated with arrest at G(1)-S transition in a dose-depending manner. In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3, orally administered PD173074 suppressed tumor growth and induced apoptotic changes comparable with the results of our in vitro assay. These findings elucidated the effectiveness of molecular targeted approach for bladder UC harboring FGFR3 mutations and the potential utility to decrease the intravesical recurrence of nonmuscle invasive bladder UC after transurethral surgical resection. Uses: Differentiation, self-renewal. Alternative Names: PD173074; PD 173074; PD-173074. Grades: 0.98. CAS No. 219580-11-7. Molecular formula: C28H41N7O3. Mole weight: 523.682. | |
| PD-173955 | PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth. Alternative Names: PD173955; PD 173955; PD-173955. Grades: 0.98. CAS No. 260415-63-2. Molecular formula: C21H16Cl2N4OS. Mole weight: 443.35. | |
| PD-1-IN-17 | PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor. PD-1-IN-17 was first reported in patent WO2015033301A1, (Compound 12), inhibits 92% splenocyte proliferation at 100 nM. Alternative Names: PD1-IN-1. CAS No. 1673560-66-1. Molecular formula: C13H22N6O7. Mole weight: 374.35. | |
| PD-1/PD-L1 inhibitor 2 | The programmed death-1 / programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM. Alternative Names: BMS-202; BMS 202; BMS202. Grades: 98%. CAS No. 1675203-84-5. Molecular formula: C25H29N3O3. Mole weight: 419.52. | |
| PD98059 | PD98059 is a potent, selective and cell-permeant inhibitor of MAP kinase kinase. It enhances human embryonic stem cell self-renewal. Alternative Names: PD-98059; 2-(2-amino-3-methoxyphenyl)chromen-4-one. Grades: >98%. CAS No. 167869-21-8. Molecular formula: C16H13NO3. Mole weight: 267.284. | |
| pdUppA-3'-p | pdUppA-3'-p, a pyrophosphate-linked oligonucleotide, is the most potent low molecular weight inhibitor of RNase. Alternative Names: 5'-phospho-2'-deoxyuridine-3-pyrophosphate (P-->5)-adenosine-3-phosphate. Grades: ≥90%. | |
| Pedatisectine F | Pedatisectine F is an alkaloid isolated from the tubers of Pinellia pedatisecta Schott. Alternative Names: 2-Methyl-6-(1,2,3,4-tetrahydroxybutyl)pyrazine; 1-(6-Methyl-2-pyrazinyl)-1,2,3,4-butanetetrol. Grades: 99.0%. CAS No. 206757-32-6. Molecular formula: C9H14N2O4. Mole weight: 214.221. | |
| Pediocin PA 1 TFA | Pediocin PA 1 TFA. | |
| Pefloxacin-[d5] | Pefloxacin-[d5] is the labelled analogue of Pefloxacin, which is a quinolone antibiotic used to treat bacterial infections. Alternative Names: Pefloxacin-D5; 1-Ethyl-D5-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Pefloxacine-d5; Pefloxacino-d5; Pefloxacinum-d5; PFLX-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 1228182-51-1. Molecular formula: C17H15D5FN3O3. Mole weight: 338.39. | |
| Peiminine | Peiminine is an alkaloid isolated from Fritillaria. Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. Peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL. Uses: Moistening lung. Alternative Names: Verticinone; Raddeanine. Grades: >98%. CAS No. 18059-10-4. Molecular formula: C27H43NO3. Mole weight: 429.64. | |
| Peimisine | Peimisine is an alkaloid FR 5 from Fritillaria thunbergii, and an angiotensin converting enzyme inhibitory steroidal alkaloid. It is a commonly used antitussive and expectorant herb in traditional Chinese medicine. Uses: Antitussive; anti-ulcer. Alternative Names: Ebeiensine. Grades: >98%. CAS No. 19773-24-1. Molecular formula: C27H41NO3. Mole weight: 427.62. | |
| Pelirine | Pelirine is isolated from the roots of Rauvolfia verticillata. Alternative Names: 10-Methoxyepiaffinine. Grades: 96%. CAS No. 30435-26-8. Molecular formula: C21H26N2O3. Mole weight: 354.5. | |
| Pemetrexed Disodium | Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Alternative Names: LY231514 disodium; Alimta; Rolazar; Tifolar; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2); L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt; LY-231514 disodium; LY 231514 disodium; Pemetrexed sodium; sodium (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate. Grades: >98%. CAS No. 150399-23-8. Molecular formula: C20H19N5Na2O6. Mole weight: 471.37. | |
| Pemetrexed Impurity D | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. CAS No. 144051-68-3. Molecular formula: C25H28N6O9. Mole weight: 556.54. | |
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