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N2-Losartanyl-losartan
An impurity of Losartan potassium. Losartan potassium is an angiotensin II receptor blocker (ARB) used primarily to treat hypertension and related cardiovascular conditions. Alternative Names: Losartan Potassium Impurity M; [2-Butyl-1-[[2'-[2-[[2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-4-chloro-1H-imidazol-5-yl]methanol; Losartan Impurity M; Losartan Potassium EP Impurity M; 2-Butyl-1-[[2'-[2-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: >95%. CAS No. 230971-72-9. Molecular formula: C44H44Cl2N12O. Mole weight: 827.81.
N-(2-Methoxy-5-methylphenyl)-acetamide
N-(2-Methoxy-5-methylphenyl)-acetamide, a chemical compound of interest, has potential applications in biomedical research as a putative analgesic, anti-inflammatory and antipyretic agent, as well as in the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's. Coherent research is warranted to ascertain its full pharmaceutical potential. Alternative Names: 3-acetylamino-4-methoxytoluene; 6-Methoxy-meta-acetoluidide; 2-Methoxy-5-Methyl-N-Acetanilide; Acetyl-p-Cresidine; Acetocresidine; forpigments; Acetyl Cresidine. Grades: 95%. CAS No. 6962-44-3. Molecular formula: C10H13NO2. Mole weight: 179.22.
N-(2-methyl-4-oxopentan-2-yl)-sulfamethoxazole
An impurity of Sulfamethoxazole, which is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Grades: 98.0%. Molecular formula: C16H21N3O4S.
N-[3,5-Bis(trifluoromethyl)phenyl]-N-[(8a,9S)-6-methoxy-9-cinchonanyl]thiourea (CAS# 852913-16-7 ) is a useful research chemical. Alternative Names: 9-(3-(3,5-Bis(trifluoromethyl)phenyl)thioureido)-(epi-quinine). Grades: 98 %. CAS No. 852913-16-7. Molecular formula: C29H28F6N4OS. Mole weight: 594.61.
N-(3-Aminopropyl)methacrylamide Hydrochloride
N-(3-aminopropyl)-2-methylprop-2-enamide hydrochloride is hydrolytically stable for preparation of polymers containing primary amine functionality. Alternative Names: N-(3-aminopropyl)-2-methyl-2-propenamide;hydrochloride; N-(3-aminopropyl)-2-methylprop-2-enamide;hydrochloride. Grades: > 98 %. CAS No. 72607-53-5. Molecular formula: C7H15ClN2O. Mole weight: 178.66.
N-(3-Hydroxypropyl)phthalimide
N-(3-Hydroxypropyl)phthalimide (CAS# 883-44-3) is a useful research chemical. Alternative Names: 2-(3-Hydroxypropyl)isoindoline-1,3-dione; 3-Phthalimido-1-propanol. Grades: 95 %. CAS No. 883-44-3. Molecular formula: C11H11NO3. Mole weight: 205.21.
N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide is an impurity of Afatinib, which is a tyrosine kinase inhibitor used to treat non-small cell lung carcinoma (NSCLC). Uses: Antineoplastic agents. Alternative Names: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-; (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: 98%. CAS No. 439081-18-2. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94.
An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Alternative Names: N-[[4-(5-methyl-3-phenylisoxazol-4-yl)phenyl]sulfonyl]acetamide. CAS No. 198471-06-6. Molecular formula: C18H16N2O4S. Mole weight: 356.4.
N'-[(6-Methyl-2-pyridyl)methylene]pyrrolidine-1-carbothiohydrazide, a chemical entity with an aptitude for disrupting tumor metastasis, has recently proven to be quite efficacious. Its ability to suppress the growth of various cancerous cells has been demonstrated in numerous studies. When used judiciously, this agent could be quite promising in the treatment of cancer, opening up alternate therapeutic avenues. Alternative Names: 1-Pyrrolidinecarbothioic acid, [(6-methyl-2-pyridinyl)methylene]hydrazide; N'-[(6-Methyl-2-pyridinyl)methylene]-1-pyrrolidinecarbothiohydrazide. Grades: ≥98%. CAS No. 907549-72-8. Molecular formula: C12H16N4S. Mole weight: 248.35.
N-acetic acid-1-amino-3-adamantanol
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Alternative Names: Vildagliptin Impurity 4; (3-hydroxyadamantan-1-ylamino)acetic acid; 2-((3-Hydroxyadamantan-1-yl)amino)acetic acid. CAS No. 1032564-18-3. Molecular formula: C12H19NO3. Mole weight: 225.29.
N-Acetyl-3-iodo-L-tyrosine hemihydrate
N-Acetyl-3-iodo-L-tyrosine hemihydrate, a chemical reagent with notable significance in studying enzyme inhibitors and protein synthesis, is widely utilized in the medical research community to develop promising drug therapies for thyroid disorders and cancers. Such compounds may also be used to synthesize radioiodinated compounds, essential in the realm of medical imaging and diagnostics. Uses: Thyronine analog. Alternative Names: L-Tyrosine, N-acetyl-3-iodo-, hydrate (2:1). CAS No. 23277-49-8. Molecular formula: C22H26I2N2O9. Mole weight: 716.3.
N-Acetyldelectine
N-Acetyldelectine is a norditerpenoid alkaloid isolated from the aerial parts of Delphinium formosum. Alternative Names: 14-Deacetylajadine; 14-Demethylajacine. Grades: 97.5%. CAS No. 63596-61-2. Molecular formula: C33H46N2O9. Mole weight: 614.736.
N-Acetyldesloratadine
N-Acetyldesloratadine is an effective and orally active dual antagonist of platelet-activating factor and histamine. N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine. Alternative Names: Sch-37370; Sch 37370; Sch37370; 1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone; 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine. Grades: ≥95%. CAS No. 117796-52-8. Molecular formula: C21H21ClN2O. Mole weight: 352.86.
N-acetyldopamine
N-acetyldopamine, an organic chemical compound, exhibits significant therapeutic potential in various neurodegenerative disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), and depression. It has been extensively researched for its ability to act as an antioxidant and anti-inflammatory agent, enabling it to provide effective treatment against a host of oxidative stress disorders. Its clinical efficacy in treating these complex neurological conditions has made it a valuable compound in pharmaceutical research, with an ever-increasing scientific interest in unlocking its potential benefits. Alternative Names: N-acetyldopamine. Grades: 95%. CAS No. 2494-12-4. Molecular formula: C10H13NO3. Mole weight: 195.218.
N-Acetyl Sitagliptin
N-Acetyl Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: 7-[(3R)-3-[(N-Acetyl)Amino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; N-[(2R)-4-Oxo-4-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]acetamide. Grades: >95%. CAS No. 1379666-94-0. Molecular formula: C18H17F6N5O2. Mole weight: 449.35.
N-Acetylstepharine
N-Acetylstepharine is an alkaloid isolated from Stephania longa. Alternative Names: N-Acetylstepharine; Stepharine, 6-acetyl-; Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one, 1'-acetyl-2',3',8',8'a-tetrahydro-5',6'-dimethoxy-, (R)-. Grades: 97.0%. CAS No. 4880-87-9. Molecular formula: C20H21NO4. Mole weight: 339.391.
N-Acetyl sulfadiazine
N-Acetyl sulfadiazine is a metabolite of sulfadiazine, an antibiotic used for the treatment of bacterial infections. Uses: A major metabolite of sulfadiazine. Alternative Names: 2-[(p-Acetamidophenyl)sulfonamido]pyrimidine; N4-Acetylsulfadiazine; 4'-(2-Pyrimidinylsulfamoyl)acetanilide; 4N-Acetylsulfadiazine; N(4)-Acetylsulfadiazine; N4-Acetylsulfadiazine. CAS No. 127-74-2. Molecular formula: C12H12N4O3S. Mole weight: 292.31.
Nacubactam
Nacubactam is a beta-lactamase inhibitor used for treating bacterial infections. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Alternative Names: OP-0595; RG-6080; FPI-1459. Grades: 99%. CAS No. 1452458-86-4. Molecular formula: C9H16N4O7S. Mole weight: 324.31.
NaDMDTC-[d6] dihydrate
NaDMDTC-[d6] dihydrate is a labelled analogue of sodium dimethyldithiocarbamate hydrate. Alternative Names: Dimethyl-D6-dithiocarbamic acid sodium salt hydrate. Grades: 95% by HPLC; 98% atom D. Molecular formula: C3D6NNaS2·2H2O. Mole weight: 185.27.
Nafoxidine HCl
Nafoxidine HCl is the hydrochloride salt of nafoxidine. Nafoxidine, structurally related to Tamoxifen, is a non-steroidal partial estrogen antagonist. Alternative Names: 1-[2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine;hydrochloride; NAFOXIDINEHYDROCHLORIDE; NafoxidineHCl; 1847-63-8; U11100A. Grades: 95%. CAS No. 1847-63-8. Molecular formula: C29H32CINO2. Mole weight: 462.03.
Nagilactone B
Nagilactone B is isolated from the herbs of Podocarpus neriifolius. Alternative Names: (1S)-1,2,3,3a,5aβ,6,10b,10cβ-Octahydro-1,2α,6α-trihydroxy-3aβ,10bα-dimethyl-7-isopropyl-4H,9H-furo[2',3',4':4,5]naphtho[2,1-c]pyran-4,9-dione. Grades: > 95%. CAS No. 19891-51-1. Molecular formula: C19H24O7. Mole weight: 364.4.
N-Allylurea
N-Allylurea is a compound that functions as a precursor in the synthesis of various organic compounds. It acts as a reactant in the production of polymers and agrochemicals. Alternative Names: Allylurea; 1-Allylurea; Allylcarbamide; Monoallylurea; Urea, 2-propenyl-; N-2-Propenylurea; 1-prop-2-en-1-ylurea. Grades: 98%. CAS No. 557-11-9. Molecular formula: C4H8N2O. Mole weight: 100.12.
Naloxegol oxalate
Naloxegol oxalate is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation. Alternative Names: Morphinan-3,14-diol, 4,5-epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-, (5α,6α)-, ethanedioate (1:1); AZ 13337019 oxalate; AZ13337019 oxalate; AZ-13337019 oxalate; Moventig; NKTR 118 oxalate; (4R,4aS,7S,7aR,12bS)-7-((2,5,8,11,14,17,20-heptaoxadocosan-22-yl)oxy)-3-allyl-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol oxalate. Grades: >98%. CAS No. 1354744-91-4. Molecular formula: C36H55NO15. Mole weight: 741.82.
Nampt activator-1
Nampt activator-1. CAS No. 701929-65-9.
(±)-Naproxen-[d3]
(±)-Naproxen-[d3] is the labelled racemic of Naproxen, which is a non-selective COX inhibitor. Alternative Names: (±)-Naproxen-D3; 2-(6-Methoxy-D3-naphthalen-2-yl)-propionic acid; 6-(Methoxy-d3)-α-methyl-2-naphthaleneacetic Acid; (±)-Naproxen-d3 (alpha-methyl-d3); rac Naproxen-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 958293-79-3. Molecular formula: C14H11D3O3. Mole weight: 233.28.
Naquotinib
Naquotinib is an irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity with IC50 of 8-33 nM toward EGFR mutants. Alternative Names: ASP 8273; ASP8273; ASP-8273; (R)-5-((1-acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide. Grades: ≥98%. CAS No. 1448232-80-1. Molecular formula: C30H42N8O3. Mole weight: 562.719.
Naratriptan Hydrochloride
Naratriptan is a triptan agent that is used for the treatment of migraine headaches. Uses: Serotonin 5-ht1 receptor agonists. Alternative Names: Naratriptan HCl; Naratriptan Hydrochloride; Amerge; Naramig; GR-85548A; GR 85548A; GR85548A. Grades: >98%. CAS No. 143388-64-1. Molecular formula: C17H25N3O2S.HCl. Mole weight: 371.93.
Nardoeudesmol A
Nardoeudesmol A is a natural compound derived from Nardostachys chinensis. With its potent anti-inflammatory and anti-cancer properties, this molecule holds potential in the biomedical industry for the development of drugs targeting various diseases, such as inflammation-related disorders and certain types of cancers. Grades: 96.5%. CAS No. 1445952-30-6. Molecular formula: C15H24O2. Mole weight: 236.354.
Nardosinone
Nardosinone, coming from the roots of Nardostachys jatamansi DC, enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. It could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. Uses: Antidepressant / sedative. Alternative Names: (3aR)-1,3aβ,4,7,8,9,9a,9bβ-Octahydro-1,1,9β,9aβ-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one; 1,1,9β,9aβ-Tetramethyl-3aβ,7,8,9,9a,9bβ-hexahydro-1H-naphtho[2,1-c][1,2]dioxole-5(4H)-one; (3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one; 5H-Naphtho[2,1-c][1,2]dioxol-5-one,1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)-. Grades: >98%. CAS No. 23720-80-1. Molecular formula: C15H22O3. Mole weight: 250.33.
Naringenin chalcone
Naringenin chalcone is a natural chalconoid that can be isolated from tomato skin. It exhibits antioxidant, anti-inflammatory, and anti-allergic properties. Alternative Names: Chalconaringenin; Isosalipurpol; trans-2'4'6'4-tetrahydroxychalcone. CAS No. 73692-50-9. Molecular formula: C15H12O5. Mole weight: 272.25.
Naronapride dihydrochloride
Naronapride is a selective 5-HT(4) receptor agonist for gastrointestinal motility disorders. It can accelerate overall colonic transit and tend to accelerate GE and AC emptying and loose stool consistency. In Nov 2016, Renexxion planed two phase III trials for Constipation in USA. Alternative Names: ATI-7505 BIS HCl; ATI 7505 BIS HCl; ATI7505 BIS HCl. CAS No. 860169-57-9. Molecular formula: C27H43Cl3N4O5. Mole weight: 610.
Nasunin
Nasunin is an anthocyanin isolated as purple colored crystals from eggplant peels. It possesses antiangiogenic activity. Alternative Names: Delphanin; Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside. CAS No. 28463-30-1. Molecular formula: C42H47ClO23. Mole weight: 955.27.
N-benzyl-9Z,12Z,15Z-octadecatrienamide
Utilized in the realm of biomedical study as an inhibitor of protein kinase, the synthetically derived N-benzyl-9Z,12Z,15Z-octadecatrienamide displays potent efficacy in quelling the proliferation of human cancer cells, thereby evidencing its likelihood as a front-runner in the development of cancer therapy. Alternative Names: N-benzyllinolenamide. Grades: >98%. CAS No. 883715-18-2. Molecular formula: C25H37NO. Mole weight: 367.6.
Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Alternative Names: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate. Grades: 95 %. CAS No. 286961-14-6. Molecular formula: C16H28NO4B. Mole weight: 309.21.
N-Boc-O-(mesitylsulfonyl)hydroxylamine
N-Boc-O-(mesitylsulfonyl)hydroxylamine (CAS# 36016-39-4) is a useful reagent for the enantioselective aziridination of α,β-unsaturated aldehydes. Alternative Names: 2,4,6-trimethylbenzenesulfonic acid [[(2-methylpropan-2-yl)oxy-oxomethyl]amino] ester; [(2-methylpropan-2-yl)oxycarbonylamino] 2,4,6-trimethylbenzenesulfonate. CAS No. 36016-39-4. Molecular formula: C14H21NO5S. Mole weight: 315.39.
N-BOC Palbociclib
N-BOC Palbociclib. CAS No. 1651214-74-2.
N-BOC Palbociclib Hydrochloride
N-BOC Palbociclib Hydrochloride. CAS No. 1883672-48-7.
N-Boc-(tosyl)methylamine
N-Boc-(tosyl)methylamine is a useful research chemical. Alternative Names: tert-Butyl (tosylmethyl)carbamate; (Toluene-4-sulfonylmethyl)carbamic acid. Grades: 95%. CAS No. 433335-00-3. Molecular formula: C13H19NO4S. Mole weight: 285.36.
n-Butylidenephthalide
antiarrhythmic. Uses: Antiarrhythmic. Alternative Names: 1(3H)-Isobenzofuranone, 3-butylidene-; Phthalide, 3-butylidene-; 3-Butylidene-1(3H)-isobenzofuranone; Butylidenephthalide; 3-Butylidenephthalide; Ligusticum lactone; NSC 325307. Grades: >98% (mixture of cis and trans isomers). CAS No. 551-08-6. Molecular formula: C12H12O2. Mole weight: 188.22.
N-(Chloroacetoxy)succinimide
N-(Chloroacetoxy)succinimide is a reagent used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins. Alternative Names: 1-[(chloroacetyl)oxy]pyrrolidine-2,5-dione; 2-chloro-Acetic acid 2,5-dioxo-1-pyrrolidinyl ester. CAS No. 27243-15-8. Molecular formula: C6H6ClNO4. Mole weight: 191.57.
N-cis-FeruloyltyraMine
N-cis-Feruloyltyramine is isolated from the herbs of Tinospora tuberculata. Alternative Names: cis-N-Feruloyltyramine. Grades: >=95%. CAS No. 80510-09-4. Molecular formula: C18H19NO4. Mole weight: 313.4.
N-Cocoyl-L-Glutamic Acid
N-Cocoyl-L-Glutamic Acid is a chemical compound derived from coconut oil. It has surfactant properties, making it useful in the manufacturing of personal care products such as shampoos and cleansing bars. Uses: Cosmetic raw materials. Alternative Names: Cocoyl Glutamate Acid; Softan CG-A. Grades: ≥95%. CAS No. 210357-12-3.
N-Decylpropane-1,3-diamine
N-Decylpropane-1,3-diamine is a useful research chemical. Alternative Names: N-decyl-propanediyldiamine; N-decyl-1,3-propanediamine. CAS No. 5538-99-8. Molecular formula: C13H30N2. Mole weight: 214.39.
N-Desmethyl Atomoxetine HCl
N-Desmethyl Atomoxetine HCl is a metabolite of Atomoxetine. It is dual-acting serotonin-norepinephrine reuptake inhibitor and NMDA antagonists for treatment of genitourinary disorders. Alternative Names: Desmethyl Atomoxetine Hydrochloride; γ-(2-Methylphenoxy)benzenepropanamine Hydrochloride. Grades: > 95%. CAS No. 881995-46-6. Molecular formula: C16H20NOCl. Mole weight: 277.79.
N-Desmethyl Azelastine
N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Alternative Names: Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity. Grades: > 95%. CAS No. 47491-38-3. Molecular formula: C21H22ClN3O. Mole weight: 367.88.
N-Desmethyl citalopram-[d4] oxalate
N-Desmethyl citalopram-[d4] oxalate is a deuterated compound of N-Desmethyl citalopram Oxalate, which is an impurity of Citalopram. CAS No. 2747915-54-2. Molecular formula: C21H17D4FN2O5. Mole weight: 404.42.
N-Desmethyl Citalopram Oxalate
An impurity of Citalopram, an antidepressant of the selective serotonin reuptake inhibitor class. Alternative Names: N-Desmethyl Citalopram Oxalate salt; Desmethylcitalopram oxalate; 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile oxalate. CAS No. 62498-68-4. Molecular formula: C21H21FN2O5. Mole weight: 400.4.
N-Desmethyl Dofetilide
N-Desmethyldofetilide is a derivative of Dofetilide. Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug. Alternative Names: Dofetilide USP Related Compound A; Dofetilide Impurity 1; Methanesulfonamide, N-[4-[2-[[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-; N-(4-(2-((4-(Methylsulfonamido)phenethyl)amino)ethoxy)phenyl)methanesulfonamide. Grades: ≥95%. CAS No. 176447-94-2. Molecular formula: C18H25N3O5S2. Mole weight: 427.54.
N-Desmethyl Edoxaban Hydrochloride
N-Desmethyl Edoxaban Hydrochloride is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Alternative Names: Edoxaban M6; N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide Hydrochloride. Grades: 95%. CAS No. 480449-52-3. Molecular formula: C23H29Cl2N7O4S. Mole weight: 570.49.
N-Desmethyltamoxifen
N-Desmethyltamoxifen is a metabolite of tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Alternative Names: Desmethyltamoxifen; Tamoxifen EP Impurity F; 2-[4-[(Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy]-N-methylethan-1-amine; N-Demethyltamoxifen; Demethyltamoxifen; 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine; (2-(4-((1Z)-1,2-Diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amine; 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N-methylethanamine; (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethylamine; Tamoxifen Citrate EP Impurity F; Tamoxifen Citrate Impurity F; Tamoxifen Impurity F. Grades: 95%. CAS No. 31750-48-8. Molecular formula: C25H27NO. Mole weight: 357.49.
N-Desmethyl Tamoxifen-[d5]
An isotope labelled metabolite of Tamoxifen. Tamoxifen is a medication that is used to treat breast cancer. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 164365-16-6. Molecular formula: C25H22D5NO. Mole weight: 362.52.
N-Desmethyl Ulipristal Acetate
N-Desmethyl Ulipristal Acetate is a metabolite of Ulipristal. Ulipristal is a selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. Alternative Names: (11β)-17-(Acetyloxy)-11-[4-(methylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione; CDB 3877; N-Monodemethyl CDB 2914. CAS No. 159681-66-0. Molecular formula: C29H35NO4. Mole weight: 461.61.
N-Desmethyl Vandetanib
N-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Alternative Names: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(4-piperidinylmethoxy)-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(piperidin-4-yl)methoxy]quinazoline. CAS No. 338992-12-4. Molecular formula: C21H22BrFN4O2. Mole weight: 461.34.
N-Despropyl-N-ethyl Macitentan
N-Despropyl-N-ethyl Macitentan is an impurity of Macitentan, which is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Alternative Names: Macitentan N-Ethyl Analog; Macitentan N-Despropyl-N-Ethyl; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-ethylsulfamide. Grades: 98%. CAS No. 441796-13-0. Molecular formula: C18H18Br2N6O4S. Mole weight: 574.25.
N-Despropyl Ropinirole HCl
An impurity of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Alternative Names: 4-(2-(propylamino)ethyl)indolin-2-one hydrochloride. Grades: > 95%. CAS No. 173990-76-6. Molecular formula: C13H18N2O.HCl. Mole weight: 254.76.
(+)-Nebivolol
Dexnebivolol is an enantiomer of Nebivolol which is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and left ventricular failure in Europe. It is highly cardioselective under certain circumstances. Uses: Treatment of hypertension and left ventricular failure. Alternative Names: R67138; R-67138; R 67138; Dexnebivolol; (S,R,R,R)-nebivolol; Bystolic; D-Nebivolol; (αR,α'R,2R,2'S)-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol]. Grades: 95%. CAS No. 118457-15-1. Molecular formula: C22H25F2NO4. Mole weight: 405.44.
Necrostatin-1
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM. Alternative Names: Necrostatin-1; Necrostatin1; Necrostatin 1; Nec-1; Nec 1; Nec1. Grades: >98%. CAS No. 4311-88-0. Molecular formula: C13H13N3OS. Mole weight: 259.33.
Necrosulfonamide
Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Alternative Names: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1360614-48-7. Molecular formula: C18H15N5O6S2. Mole weight: 461.47.
Nedocromil sodium
Nedocromil sodium is a mast cell stabilizer that prevents wheezing, shortness of breath, and other breathing problems caused by asthma. Alternative Names: 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt (1:2); 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid Disodium Salt; Alocril; FPL 59002KP; Nedocromil disodium salt; Rapitil; Tayled; Tilade; Tilarin; 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt. Grades: 95%. CAS No. 69049-74-7. Molecular formula: C19H15NNa2O7. Mole weight: 415.30.
Nefiracetam
Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Uses: Neuroprotective agents. Alternative Names: Nefiracetam; 77191-36-7; N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide; Translon; DM 9384. Grades: >98%. CAS No. 77191-36-7. Molecular formula: C14H18N2O2. Mole weight: 246.3.
Negletein
Negletein is a flavonoid with anti-inflammatory and immunomodulatory activities. Alternative Names: 5,6-Dihydroxy-7-methoxyflavone; Baicalein-7-methylether; 7-O-Methylbaicalein. Grades: >98%. CAS No. 29550-13-8. Molecular formula: C16H12O5. Mole weight: 284.26.
Nelarabine
Nelarabine acts by inhibiting DNA synthesis and inducing apoptosis in susceptible cells. Nelarabine demonstrated significant antineoplastic activity with acceptable toxicity. Alternative Names: 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine; Arranon; MAY; Nelzarabine; 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine; NSC-686673; (2R,3S,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥98% by HPLC. CAS No. 121032-29-9. Molecular formula: C11H15N5O5. Mole weight: 297.27.
Nemoralisin
Nemoralisin is a natural diterpenoid found in the stem bark of Aphanamixis polystachya. Alternative Names: 6-[(1E)-6-(5,5-Dimethyl-4-oxo-4,5-dihydro-2-furanyl)-2-methyl-1-h epten-1-yl]-4-methyl-5,6-dihydro-2H-pyran-2-one. Grades: >97%. CAS No. 942480-13-9. Molecular formula: C20H28O4. Mole weight: 332.4.
Nemoralisin C
Nemoralisin C is a nemoralisin diterpenoids isolated from Aphanamixis polystachya (Wall.) R. Parker. Alternative Names: (6S)-6-[(1E,6S)-6-(4,5-Dihydro-5,5-dimethyl-4-oxo-2-furanyl)-6-hydroxy-2-methyl-1-hepten-1-yl]-5,6-dihydro-4-methyl-2H-pyran-2-one. Grades: >97%. CAS No. 1443421-84-8. Molecular formula: C20H28O5. Mole weight: 348.4.
Nemorubicin
Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. Uses: Adcs cytotoxin. Alternative Names: Methoxymorpholinyldoxorubicin; PNU152243A; PNU-152243A; PNU 152243A; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-[(2S)-2-methoxymorpholin-4-yl]-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-; 3'-Deamino-3'-(2(S)-methoxy-4-morpholinyl)doxorubicin; Methoxymorpholino-doxorubicin. Grades: ≥97% by HPLC. CAS No. 108852-90-0. Molecular formula: C32H37NO13. Mole weight: 643.23.
Neobyakangelicol
Neobyakangelicol has antioxidative activity, which is isolated from the roots of Angelica dahurica. Uses: Anti-oxidative. Alternative Names: (-)-9-(2-Hydroxy-3-methyl-3-butenyloxy)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one. Grades: >95%. CAS No. 35214-82-5. Molecular formula: C17H16O6. Mole weight: 316.3.
Neocaesalpin L
Neocaesalpin L is a natural diterpenoid compound found in several plants. Alternative Names: 14-O-Demethylneocaesalpin M. Grades: >97%. CAS No. 952473-86-8. Molecular formula: C26H36O11. Mole weight: 524.557.
Neocaesalpin O
Neocaesalpin O is a natural diterpenoid compound found in several plants. Alternative Names: (1S,4aR,5S,6R,6aS,7S,11aS,11bS)-4a,7-dihydroxy-4,4,7,11b-tetramethyl-9-oxo-1,2,3,4,4a,5,6,6a,7,9,11a,11b-dodecahydrophenanthro[3,2-b]furan-1,5,6-triyl triacetate. Grades: >98%. CAS No. 1053189-53-9. Molecular formula: C26H34O10. Mole weight: 506.542.