BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Oia25-Semaglutide TFA | Oia25-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: Oia25-Semaglutide TFA; Semaglutide Impurity Oia25; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-gammaGlu-C18-OH)Glu-Phe-Ile-Ala-Oia25-Leu-Val-Arg-Gly-Arg-Gly-OH. Grades: 98%. Molecular formula: C187H291N45O60 (free base). Mole weight: 4129.60 (free base). |  |
| OICR 9429 | OICR-9429 can inhibit the interaction of WDR5 with peptide regions of MLL and histone 3 as a chemical probe. It can reduce viability of acute myeloid leukemia cells and can also disrupt MLL1-RbBP5 interaction. Alternative Names: OICR-9429; OICR 9429; OICR9429. N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide. Grades: ≥98% by HPLC. CAS No. 1801787-56-3. Molecular formula: C29H32F3N5O3. Mole weight: 555.59. | |
| Olcegepant | Olcegepant is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor, primarily explored for the prevention of migraines in adults. CGRP is a neuropeptide that plays a significant role in migraine pathophysiology, and its receptors are found in the trigeminal ganglion and the central nervous system. By blocking the CGRP receptor, olcegepant aims to prevent the activation of pain pathways associated with migraines. Alternative Names: BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS; N-((R)-1-(((S)-6-Amino-1-oxo-1-(4-(pyridin-4-yl)piperazin-1-yl)hexan-2-yl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide; 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine. CAS No. 204697-65-4. Molecular formula: C38H47Br2N9O5. Mole weight: 869.65. | |
| Olean-12-ene-3,11-diol | Olean-12-ene-3,11-diol isolated from the herbs of Celastrus angulatus. Alternative Names: 11α-Hydroxy-β-amyrin;3β,11α-Dihydroxyoleana-12-ene. Grades: 98%. CAS No. 5282-14-4. Molecular formula: C30H50O2. Mole weight: 442.7. | |
| Olean-12-ene-3,11-dione | Olean-12-ene-3,11-dione is a natural triterpenoid found in the herbs of Euonymus hederaceus Champ. ex Benth. Alternative Names: 3,11-Dioxo-β-amyrene; 5α-Oleana-12-ene-3,11-dione; 18Beta(H)-olean-12-ene-3,11-dione. Grades: >93%. CAS No. 2935-32-2. Molecular formula: C30H46O2. Mole weight: 438.7. | |
| Olean-12-ene-3,24-diol | Olean-12-ene-3,24-diol isolated from the herbs of Phyllanthus flexuosus. Alternative Names: 3beta,24-Dihydroxyolean-12-ene. Grades: 97.5%. CAS No. 119318-15-9. Molecular formula: C30H50O2. Mole weight: 442.7. | |
| Oleanolic acid - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside | Oleanolic acid - 3-O-β-D- Galactosyl( 1→3)-β-D-glucosyl( 1→3)-α-L-rhamnosyl(1→2)-α-L-arabinoside is a lupane-type triterpenoid glycoside isolated from Pulsatilla chinensis BungeRegel. Grades: > 98%. Molecular formula: C53H86O21. Mole weight: 1059.24. | |
| Oleanolic acid 3-O-β-D-glucosyl-( 1?3)-α-L-ramnosyl(1?2)-α-L-arabinoside | Oleanolic acid 3-O-β-D-glucosyl-( 1→3)-α-L-ramnosyl(1→2)-α-L-arabinoside is extracted from Pulsatilla chinensis (Bunge) Regel. Alternative Names: 3-[(O-beta-D-Glucopyranosyl-(1→3)-O-6-deoxy-alpha-L-mannopyranosyl-(1→2)-alpha-L-arabinopyranosyl)oxy]-olean-12-en-28-oic acid. Grades: >98%. CAS No. 103956-33-8. Molecular formula: C47H76O16. Mole weight: 897.1. | |
| Olmesartan Impurity 13 | One of the impurities of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Alternative Names: 5-(4'-(BROMOMETHYL)-[1,1'-BIPHENYL]-2-YL)-2H-TETRAZOLE. Grades: 95%. CAS No. 138402-33-2. Molecular formula: C14H11BrN4. Mole weight: 315.17. | |
| Olmutinib | Olmutinib, also called as HM61713 and BI-1482694, is an orally available, mutant-selective third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) that is being developed for treatment of advanced and metastatic EGFR mutation-positive non-small cell lung cancer (NSCLC). In May 2016, olmutinib received its first global approval in South Korea for the treatment of EGFR T790M mutation-positive lung cancer. Olmutinib is also a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). Alternative Names: N-(3-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-4-yl)oxy)phenyl)acrylamide; HM61713; HM 61713; HM-61713; BI 1482694; BI-1482694; BI1482694; Olmutinib. Grades: >98%. CAS No. 1353550-13-6. Molecular formula: C26H26N6O2S. Mole weight: 486.18. | |
| Olpasiran sodium | Olpasiran is a small interfering RNA (siRNA) molecule that significantly reduces the production of Lp(a) in hepatocytes and can be used in studies related to atherosclerotic cardiovascular disease (ASCVD). Alternative Names: AMG 890 sodium; ARC-LPA sodium. Grades: 98%. Molecular formula: C490H610F11N164Na42O306P41S7. Mole weight: 16361.91. | |
| Olsalazine Sodium | Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond. It is used in the treatment of inflammatory bowel disease such as ulcerative colitis. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: OLSALAZINE SODIUM; 6054-98-4; Dipentum; Olsalazine Disodium; Disodium 5,5'-azodisalicylate; azodisal sodium; Olsalazine disodium salt; disodium azodisalicylate; CJ 91B; CJ-91B; Olsalazine sodium [USAN]; Olsalazine Sodium Salt; Sodium azodisalicylate; Olsalazine (Disodium); Sodium olsalazine; Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt; C. I. Mordant Yellow 5, disodium salt; Y7JEW0XG7I; Benzoic acid, 3,3'-azobis(6-hydroxy-, disodium salt; sodium (E)-5,5'-(diazene-1,2-diyl)bis(2-hydroxybenzoate). Grades: >98%. CAS No. 6054-98-4. Molecular formula: C14H8N2O6.2Na. Mole weight: 346.2. | |
| Olumacostat glasaretil | OG (Olumacostat glasaretil) is a acetyl-coenzyme A carboxylase inhibitor. Acetyl-COA carboxylase is the key point for the first, rate-limiting step in de novo fatty acid synthesis. OG can inhibit in vitro human sebocyte lipid production, it can also reduce in vivo sebaceous gland size in hamster ears. Alternative Names: Olumacostat glasaretil; DRM01B; DRM-01B; DRM 01B. 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate. Grades: 98%. CAS No. 1261491-89-7. Molecular formula: C26H43NO7. Mole weight: 481.63. | |
| Omadacycline mesylate | Omadacycline mesylate is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome. Alternative Names: PTK 0796 mesylate; PTK-0796 mesylate; PTK0796 mesylate; Amadacycline mesylate. Grades: >98%. CAS No. 1196800-40-4. Molecular formula: C30H44N4O10S. Mole weight: 652.76. | |
| Omapatrilat | Omapatrilat, an octahydropyridothiazepine derivative, has been found to be an ACE inhibitor as well as an endopeptidase inhibitor and was once studied in heart failure and hypertension. Uses: For research use only. Alternative Names: Omapatrilat; BMS 186716; BMS-186716; BMS186716; Vanlev; UNII-36NLI90E7T; CHEMBL289556; (4S,7S,10aS)-5-oxo-4-[[(2S)-3-phenyl-2-sulfanylpropanoyl]amino]-2,3,4,7,8,9,10,10a-octahydropyrido[2,1-b][1,3]thiazepine-7-carboxylic acid. Grades: 98%. CAS No. 167305-00-2. Molecular formula: C19H24N2O4S2. Mole weight: 408.53. | |
| Omarigliptin | Omarigliptin is a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as the treatment for type 2 diabetes. Alternative Names: MK-3102; MK3102; MK 3102; (2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-methylsulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)oxan-3-amine. Grades: 98%. CAS No. 1226781-44-7. Molecular formula: C17H20F2N4O3S. Mole weight: 398.429. | |
| Ombuoside | Ombuoside isolated from the herbs of Scutellaria barbata D. Don. Uses: Antifungal activity; antioxidant activity. Alternative Names: 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-3',5-dihydroxy-4',7-dimethoxyflavone;3-[6-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy]-3',5-dihydroxy-4',7-dimethoxyflavone. Grades: 0.99. CAS No. 20188-85-6. Molecular formula: C29H34O16. Mole weight: 638.6. | |
| Omecamtiv mecarbil | Omecamtiv mecarbil is a cardiac-specific myosin activator with an EC50 of 0.6 μM. Alternative Names: Omecamtiv mecarbil; CK1827452; CK 1827452; CK1827452. Grades: >98%. CAS No. 873697-71-3. Molecular formula: C20H24FN5O3. Mole weight: 401.43. | |
| Omeprazole Impurity 13 | Omeprazole Impurity 13 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Alternative Names: 4-Desmethoxy-4-Chloro Omeprazole Sulfide; 5-Methoxy-2-[[(4-Chloro-3,5-Dimethylpyridin-2-yl)methyl]sulphanyl]-1H-Benzimidazole. Grades: >97%. CAS No. 220757-74-4. Molecular formula: C16H16ClN3OS. Mole weight: 333.84. | |
| Omeprazole N1-Methyl 6-Methoxy Thiol Impurity | Omeprazole N1-Methyl 6-Methoxy Thiol Impurity is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Alternative Names: 6-Methoxy-1-methyl-1H-benzimidazole-2-thiol; 6-Methoxy-1-methyl-1,3-dihydro-2H-benzo[d]imidazole-2-thione. Grades: 98%. CAS No. 1526768-06-8. Molecular formula: C9H10N2OS. Mole weight: 194.25. | |
| Omeprazole Related Compound 15 | Omeprazole Related Compound 15 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: Impurity c from the synthesis of omeprazole. Alternative Names: 4-Desmethoxy-4-nitro Omeprazole; 2-[[(3,5-Dimethyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole; 5-Methoxy-2-{(S)-[(4-nitro-3,5-dimethyl-pyridine-2-yl)methyl]sulfinyl}-1H-benzimidazole; rac 4-Desmethoxy-4-nitro Omeprazole. Grades: >98%. CAS No. 317807-10-6. Molecular formula: C16H16N4O4S. Mole weight: 360.39. | |
| Onalespib | Onalespib, also known as AT13387, is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. AT13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Alternative Names: AT13387; AT 13387; AT-13387. Grades: >98%. CAS No. 912999-49-6. Molecular formula: C24H31N3O3. Mole weight: 409.52. | |
| Oncrasin-1 | Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations. It also led to abnormal aggregation of PKCΙ in nucleus of sensitive cells but not in resistant cells. Alternative Names: 1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde. Grades: 98 %. CAS No. 75629-57-1. Molecular formula: C16H12ClNO. Mole weight: 269.73. | |
| Onitin | Onitin isolated from the herbs of Onychium japonicum. It shows super-oxide and DPPH free radical scavenging effects, and exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Uses: Hepatoprotective activity. Alternative Names: 2,3-Dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-inden-1-one;1H-Inden-1-one,2,3-dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetraMethyl-; 4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-3H-inden-1-one. Grades: 0.985. CAS No. 53823-02-2. Molecular formula: C15H20O3. Mole weight: 248.3. | |
| Onjisaponin B | Onjisaponin B is extracted from the roots of Polygala tenuifolia. It was able to induce autophagy and accelerate both the removal of mutant huntingtin and A53T α-synuclein, which are highly associated with Huntington disease and Parkinson disease, respectively. It induces autophagy via the AMPK-mTOR signaling pathway. It increased the NGF level and may have potential therapeutic effects for the treatment of Alzheimer disease patients. Alternative Names: Senegin III; Sinegin 3. Grades: >98%. CAS No. 35906-36-6. Molecular formula: C75H112O35. Mole weight: 1573.7. | |
| ONO-4059 | ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Alternative Names: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one; ONO-4059; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. Grades: 98%. CAS No. 1351636-18-4. Molecular formula: C25H22N6O3. Mole weight: 454.48. | |
| ONO-4059 (hydrochloride) | ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Alternative Names: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Molecular formula: C25H23ClN6O3. Mole weight: 490.95. | |
| ONO-AE3-208 | ONO-AE3-208 is an EP4 antagonist (Ki values are 1.3, 30, 790 and 2400 nM for EP4, EP3, FP and TP receptors respectively), which less potently affects EP3, FP, and TP receptors. Uses: An ep4 antagonist. Alternative Names: ONO-AE3-208; ONO-AE-3-208; ONO-AE 3-208; AE 3-208; AE-3-208; AE3-208; ONO AE3 208 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid; 4-[4-cyano-2-[2-(4-fluoronaphthalen-1-yl)propanoylamino]phenyl]butanoic acid. Grades: ≥98%. CAS No. 402473-54-5. Molecular formula: C24H21FN2O3. Mole weight: 404.43. | |
| Ophiopogonanone E | Ophiopogonanone E is extracted from the tubers of Ophiopogon japonicus(Thunb) Ker-Gawl. It can scavenge hydrogen peroxide(H2O2) and hydroxyl radical(·OH) in vitro. It shows oxygen free radicals(OFRs) scavenging effects. Alternative Names: RubiadinOphiopogonanone E; 5,7-Dihydroxy-3-[(2-hydroxy-4-methoxyphenyl)methyl]-8-methoxy-6-methyl-2,3-dihydrochromen-4-one. CAS No. 588706-66-5. Molecular formula: C19H20O7. Mole weight: 360.36. | |
| Opicapone | Opicapone is a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase. Alternative Names: BIA 9-1067; BIA 91067; BIA-91067; BIA91067; Opicapone. Grades: >98%. CAS No. 923287-50-7. Molecular formula: C15H10Cl2N4O6. Mole weight: 413.17. | |
| o-(p-Toluylsulfonamide)aniline | o-(p-Toluylsulfonamide)aniline. Alternative Names: t-Sulfonamidine; 2-(p-Tolylsulfonylamino)aniline; Benzenesulfonamide, N-(2-aminophenyl)-4-methyl-. Grades: 95%. CAS No. 3624-90-6. Molecular formula: C13H14N2O2S. Mole weight: 262.33. | |
| Orantinib | Orantinib is a multiple receptor tyrosine kinase inhibitor with IC50s of 2.1 μM, 8 nM and 1.2 μM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively. It has greatest potency against PDGFR autophosphorylation. Alternative Names: 3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic Acid; 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic Acid; 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone; 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; NSC 702827; SU 6668; TSU-68. Grades: ≥98%. CAS No. 252916-29-3. Molecular formula: C18H18N2O3. Mole weight: 310.35. | |
| Oridonin | Oridonin, a diterpenoid purified from Rabdosia rubescens, is an antitumor agent. It also acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2. Uses: Lipoxygenase-inhibiting. Alternative Names: Rubescenin A; Oridonine; lasidonin; (14R)-7-alpha,20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one. Grades: >98%. CAS No. 28957-04-2. Molecular formula: C20H28O6. Mole weight: 364.43. | |
| ORM-15341 | ORM-15341, an androgen receptor antagonist, have potential effect against prostate cancer and is commonly found as an active main metabolite of ODM-201. IC50 = 38 nM. Alternative Names: CS-5191; ORM 15341; CS 5191; ORM15341; CS5191. Grades: 98%. CAS No. 1297537-33-7. Molecular formula: C19H17ClN6O2. Mole weight: 396.83. | |
| Oroxin A | Oroxin A is a flavonoid glycoside isolated from the herb Oroxylum indicum (L.) Kurz. It exhibits antioxidant property. Alternative Names: 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-; 7-(β-D-Glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one; 5,6,7-Trihydroxyflavone 7-O-β-D-glucopyranoside; Baicalein 7-O-glucopyranoside; Baicalein 7-O-β-D-glucopyranoside; Baicalein 7-O-β-D-glucoside; Baicalein-7-O-glucoside; Baikalin; Biacalein 7-O-glucoside; Deglucosyloroxin B. Grades: >98%. CAS No. 57396-78-8. Molecular formula: C21H20O10. Mole weight: 432.38. | |
| ortho-Hydroxy Atorvastatin Calcium Salt | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Alternative Names: 2-hydroxy Atorvastatin Calcium salt; Sodium (3R,5R)-7-(2-(4-fluorophenyl)-4-((2-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-1Hp-pyrrol-1-yl)-3,5-dihydroxyheptanoate. Grades: > 95%. CAS No. 265989-46-6. Molecular formula: C66H68CaF2N4O12. Mole weight: 1187.36. | |
| ortho-Mirabegron | ortho-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Alternative Names: 2-Amino-N-[2-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide. CAS No. 1684452-80-9. Molecular formula: C21H24N4O2S. Mole weight: 396.51. | |
| ORTHO-NORNUCIFERINE | O-Nornuciferine is a natural alkaloid compound found in several plants. Alternative Names: N-Methylasimilobine. Grades: >98%. CAS No. 3153-55-7. Molecular formula: C18H19NO2. Mole weight: 281.35. | |
| ORY-1001 dihydrochloride | ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Alternative Names: RG-6016; RG 6016; RG6016; ORY-1001 2HCl; ORY 1001 2HCl; ORY1001 2HCl; (1R,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride. Grades:>98%. CAS No. 1431326-61-2. Molecular formula: C15H24Cl2N2. Mole weight: 303.27. | |
| Osajin | Osajin is a natural flavonoid found in the herbs of Derris robusta. Through multiple apoptotic pathways, osajin can induce apoptosis in human NPC cells. Osajin also exhibits antitumor activity in different tumor cell lines. Uses: Antitumor. Alternative Names: 5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-4H,8H -pyrano[2,3-f]chromen-4-one;4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hyd roxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-. Grades: >97%. CAS No. 482-53-1. Molecular formula: C25H24O5. Mole weight: 404.5. | |
| Oseltamivir Biotin conjugate 1 | Oseltamivir Biotin conjugate 1 is a novel conjunction used for the targeted delivery of Oseltamivir, a drug for treating influenza caused by H1N1 and H3N2 strains. With the addition of Biotin, this conjugate provides selective binding to cells expressing biotin receptors, enhancing drug efficiency and reducing off-target effects. Alternative Names: Tamiphosphor, biotin conjugate. CAS No. 1612755-43-7. Molecular formula: (C2H4O)nC35H63N6O9PS. | |
| Oseltamivir-[d5] Hydrochloride | Labelled Oseltamivir, which is an acetamido cyclohexene that is a structural homolog of sialic acid and inhibits neuraminidase. Alternative Names: Oseltamivir D5 Hydrochloride. Grades: >98%. CAS No. 2140263-19-8. Molecular formula: C16H24D5ClN2O4. Mole weight: 353.89. | |
| Oseltamivir EP Impurity C | Oseltamivir EP Impurity C is the active metabolite of oseltamivir. Oseltamivir, also called as GS 4071 or Ro 64-0802, is an antiviral drug that competitively inhibits neuraminidase A and B (IC50 = 0.1 to 4.9 nM). Uses: A metabolite of oseltamivir. Alternative Names: Oseltamivir Acid (USP); Oseltamivir carboxylate; GS 4071; Ro 64-0802; Oseltamivir Carboxylic Acid. Grades: ≥98%. CAS No. 187227-45-8. Molecular formula: C14H24N2O4. Mole weight: 284.35. | |
| Oseltamivir EP Impurity F | A metabolite of Oseltamivir, which is an acetamido cyclohexene that is a structural homolog of sialic acid and inhibits neuraminidase. Alternative Names: 3-Des(1-ethylpropoxy)-3-(1-methylpropoxy) Oseltamivir; (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-methylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 1052063-37-2. Molecular formula: C15H26N2O4. Mole weight: 298.38. | |
| Oseltamivir EP Impurity G | A metabolite of Oseltamivir, which is an acetamido cyclohexene that is a structural homolog of sialic acid and inhibits neuraminidase. Alternative Names: 4-N-Desacetyl-5-N-acetyl Oseltamivir; (3R,4R,5S)-5-(Acetylamino)-4-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 956267-10-0. Molecular formula: C16H28N2O4. Mole weight: 312.41. | |
| OSI-930 | OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Alternative Names: OSI 930; OSI930. Grades: >98%. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.444. | |
| Osimertinib-[d6] | Osimertinib-[d6], is an isotope labelled derivative of Osimertinib. Osimertinib is an epidermal growth factor receptor tyrosine kinase inhibitor drug used to treat non-small-cell lung carcinomas. Alternative Names: Osimertinib D6. Grades: 95% by CP; 98% atom D. CAS No. 1638281-44-3. Molecular formula: C28H27D6N7O2. Mole weight: 505.66. | |
| OSS-128167 | OSS-128167 is a selective SIRT6 inhibitor (IC50 = 89 μM). Alternative Names: OSS 128167; OSS128167; SIRT6-IN-1; STK292625; STK 292625; STK-292625; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid. Grades: 98%. CAS No. 887686-02-4. Molecular formula: C19H14N2O6. Mole weight: 366.32. | |
| Osthenol | Osthenol is a hydroxycoumarin with antitumor-promoting, antifungal and antibacterial activity. Alternative Names: 7-hydroxy-8-prenylcoumarin. Grades: 98%. CAS No. 484-14-0. Molecular formula: C14H14O3. Mole weight: 230.3. | |
| Otophylloside B 4'''-O-α-L-cymaropyranoside | Otophylloside B 4'''-O-α-L-cymaropyranoside is a steroid compound isolated from the leaves of Cryptolepis buchanani. Grades: 97.5%. CAS No. 171422-82-5. Molecular formula: C56H90O19. Mole weight: 1067.317. | |
| Otophylloside F | Otophylloside F is a steroid compound isolated from Cynanchum otophyllum. Study indicated that Otophylloside F protects against Aβ toxicity to exhibit anti-aging effects, and potentially contributes to the Alzheimer's disease (AD) treatment. Alternative Names: Otophylloside F; 250217-73-3; [(3S,8S,9R,10R,12R,13S,14R,17S)-17-acetyl-8,14,17-trihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5R,6R)-5-[(2S,4R,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] (E)-3,4-dimethylpent-2-enoate. Grades: 95.0%. CAS No. 250217-73-3. Molecular formula: C48H76O16. Mole weight: 909.12. | |
| Otophylloside O | Otophylloside O is a steroid compound isolated from the roots of Cynanchum otophyllum. Alternative Names: Otophylloside O; 1326583-08-7; AKOS040762155. Grades: 96.5%. CAS No. 1326583-08-7. Molecular formula: C56H84O20. Mole weight: 1077.27. | |
| Otophylloside T | Otophylloside T is a steroid compound isolated from Cynanchum otophyllum. Alternative Names: Otophylloside T; AKOS040762545; 1642306-14-6. Grades: 98.0%. CAS No. 1642306-14-6. Molecular formula: C48H70O18. Mole weight: 935.073. | |
| OTS-964 hydrochloride | OTS-964, a thienoquinolin derivative, is a TOPK inhibitor and prabably be useful in studying anticancer agent as an analogue of OTS-514. It is still under preclinical trial. IC50: 28 nM. Alternative Names: OTS964; OTS 964; OTS-964. Grades: 98%. CAS No. 1338545-07-5. Molecular formula: C23H25ClN2O2S. Mole weight: 428.97. | |
| OTX015 | OTX015 is a potent BET bromodomian inhibitor, which targets the BET bromodomain proteins 2, 3, and 4 (BRD). BRDs 2, 3, and 4 are considered potential cancer targets because of their pivotal role in regulating the transcription of growth-promoting genes and cell cycle regulators. Alternative Names: OTX-015; OTX 015; MK-8628; MK 8628; MK8628; Birabresib; (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide. Grades: >98%. CAS No. 202590-98-5. Molecular formula: C25H22ClN5O2S. Mole weight: 492.00. | |
| Oxaliplatin | Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy that inhibits DNA synthesis by conforming DNA adducts in cancer cells. Alternative Names: Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum; 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-; Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1R-trans)]-; Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN,κN'][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; Dacplat; Eloxatin; Elplat; l-OHP; Lipoxal; NSC 266046; Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II); Oxalato[trans-(-)-1,2-cyclohexanediamine]platinum(II); Oxalatoplatin; Oxalatoplatinum; Platinum, (1,2-cyclohexanediamine-κN,κN')[ethanedioato(2-)-κO1,κO2]-, [SP-4-2-(1R-trans)]-; RP 54780; trans-L-Diaminocyclohexane oxalatoplatinum. Grades: >98%. CAS No. 61825-94-3. Molecular formula: C8H14N2O4Pt. Mole weight: 397.29. | |
| Oxcarbazepine EP Impurity D | An impurity of Oxcarbazepine which is an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders. Alternative Names: 5H-Dibenz[b,f]azepine-10,11-dione; Dibenzazepine-10,11-dione; Dibenzazepinodione. Grades: > 95%. CAS No. 19579-83-0. Molecular formula: C14H9NO2. Mole weight: 223.23. | |
| Oxcarbazepine EP Impurity I | An impurity of Oxcarbazepine which is an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders. Alternative Names: 11-Keto Oxcarbazepine; 10,11-Dioxo-10,11-dihydro-5H-dibenzo(b,f)azepine-5-carboxamide; 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10,11-dioxo-; 10,11-Dioxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide; 10,11-Dihydro-10,11-dioxo Carbamazepine; 10,11-Dihydro-10,11-dioxo-5H-dibenz[b,f]azepine-5-carboxamide; Oxcarbazepine Related Compound F; Carbamazepinedione. Grades: > 95%. CAS No. 537693-29-1. Molecular formula: C15H10N2O3. Mole weight: 266.26. | |
| Oxetane-3-carboxylic acid | Oxetane-3-carboxylic acid. Alternative Names: 3-Oxetanecarboxylic acid. Grades: 95 %. CAS No. 114012-41-8. Molecular formula: C4H6O3. Mole weight: 102.09. | |
| Oxfendazole | Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic. It can be used to control nematode disease and tapeworm disease in livestock. Uses: Antinematodal agents. Alternative Names: RS-8858; RS 8858; RS8858. Grades: >98%. CAS No. 53716-50-0. Molecular formula: C15H13N3O3S. Mole weight: 315.35. | |
| OXi-4503 | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide / hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Alternative Names: OXi4503; OXi 4503; CA1P; tetrasodium [3-methoxy-2-phosphonatooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate. Grades: >98%. CAS No. 288847-35-8. Molecular formula: C18H22O12P2. Mole weight: 492.31. | |
| Oxocrebanine | Oxocrebanine is an anti-breast cancer active aporphine alkaloid found in S. hainanensis. Oxocrebanine is a Topo I/IIα dual inhibitor, catalytic inhibitor and DNA intercalator. Alternative Names: 9,10-dimethoxy-8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-8-one; 8H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one, 9,10-dimethoxy-. Grades: > 95%. CAS No. 38826-42-5. Molecular formula: C19H13NO5. Mole weight: 335.31. | |
| Oxyntomodulin TFA | Oxyntomodulin is a naturally peptide hormone found in the colon, produced by the oxyntic (fundic) cells of the oxyntic (fundic) mucosa. Oxyntomodulin acts as a glucagon-like peptide 1 (GLP-1) receptor agonist. Alternative Names: Enteroglucagon TFA; Gut glucagon TFA; Enteroglucagonoid TFA; His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Lys-Arg-Asn-Lys-Asn-Asn-Ile-Ala.TFA. | |
| oxypeucedanin | Oxypeucedanin, a derivative of coumarin of natural origins, has exhibited encouraging outcomes in the management of diverse medical conditions. Its potential as a cure for inflammatory diseases like arthritis is attributed to its anti-inflammatory characteristics. Moreover, oxypeucedanin has demonstrated anticancer features, particularly in the care for breast cancer. Its capacity for inducing apoptosis and hindering tumor growth elevates it as a propitious therapeutic alternative. Alternative Names: Oxypeucedarin; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)-; 4-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one; 5-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one. Grades: >98%. CAS No. 737-52-0. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Oxypeucedaninhydrate | Oxypeucedanin hydrate usually can be found in the roots of Angelica dahurica. It exhibited carbohydrate metabolizing enzymes inhibitory effect. Uses: Antimutagenic / antioxidant / antimicrobial. Alternative Names: (+)-4-[(R)-2,3-Dihydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one; Hydroxypeucedanin hydrate; Prangol; Prangolarin hydrate; Aviprin. Grades: >98%. CAS No. 2643-85-8. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| Oxypeucedanin hydrate | Oxypeucedanin hydrate is a natural coumarin compound found in several plants. Alternative Names: (S)-(-)-Oxypeucedan hydrate. Grades: >98%. CAS No. 133164-11-1. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| Oxyresveratrol 3'-O-β-D-glucopyranoside | A derivative of Resveratrol. Resveratrol is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Alternative Names: Oxyresveratrol 3'-O-beta-D-glucopyranoside; 144525-40-6; (2S,3R,4S,5S,6R)-2-[3-[(E)-2-(2,4-dihydroxyphenyl)ethenyl]-5-hydroxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triolOxyresveratrol 3'-O-|A-D-glucopyranosideOxyresveratrol 3-O-glucoside. Grades: > 95%. CAS No. 144525-40-6. Molecular formula: C20H22O9. Mole weight: 406.39. | |
| Ozanimod | Ozanimod is a medication used for the treatment of multiple sclerosis (MS) and inflammatory bowel disease (IBD), specifically ulcerative colitis. Ozanimod is a selective sphingosine 1-phosphate (S1P) receptor modulator. It binds to S1P receptors on lymphocytes (a type of white blood cell), thereby inhibiting their egress from lymph nodes. This action reduces the number of circulating lymphocytes that can cause inflammation in the central nervous system (in the case of MS) or the intestines (in the case of ulcerative colitis). Ozanimod is indicated for the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It is also approved for the treatment of moderate to severe ulcerative colitis in adults who have not responded adequately to conventional therapies. Alternative Names: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-; 5-[3-[(1S)-2,3-Dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)benzonitrile; 5-[3-[1-(S)-(2-Hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-isopropoxybenzonitrile; RPC 1063; RPC-1063; RPC1063; Zeposia. Grades: ≥95%. CAS No. 1306760-87-1. Molecular formula: C23H24N4O3. Mole weight: 404.47. | |
| P22077 | P22077 is a potent and selective ubiquitin-specific protease 7 (USP7) inhibitor. P22077 potently induces apoptosis in NB cells with an intact USP7-HDM2-p53 axis but not in NB cells with mutant p53 or without human homolog of MDM2 (HDM2) expression. P22077 was found to be able to sensitize chemoresistant LA-N-6 NB cells to chemotherapy. In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines. USP7-specific inhibitors like P22077 may serve not only as a stand-alone therapy but also as an effective adjunct to current chemotherapeutic regimens for treating NB with an intact USP7-HDM2-p53 axis. Alternative Names: P-22077; P 22077. Grades: 0.98. CAS No. 1247819-59-5. Molecular formula: C12H7F2NO3S2. Mole weight: 315.309. | |
| P2Y14R antagonist 1 | P2Y14R antagonist 1. CAS No. 2728291-29-8. | |
Our database is helping our users find suppliers everyday.
