BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Neochamaejasmin B | Neochamaejasmin B is isolated from the roots of Stellera chamaejasme Linn. Uses: Phytotoxic; nematicidal. Alternative Names: (2R,2'S,3S,3'S)-5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-2,2',3,3'-tetrahydro-4H,4'H-3,3'-bichromene-4,4'-dione. Grades: 97%. CAS No. 90411-12-4. Molecular formula: C30H22O10. Mole weight: 542.5. |  |
| Neochinulin A | Neoechinulin A is isolated from Aspergillus chevalieri. It may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits. Uses: Antioxidant; anti-inflammatory; antioxidant / anti-nitration. Alternative Names: (3S,6Z)-3-Methyl-6-{[2-(2-methyl-3-buten-2-yl)-1H-indol-3-yl]meth ylene}-2,5-piperazinedione; (3S)-3α-Methyl-6-[(Z)-[2-(1,1-dimethyl-2-propenyl)-1H-indole-3-yl]methylene]hexahydropyrazine-2,5-dione. Grades: 97%. CAS No. 51551-29-2. Molecular formula: C19H21N3O2. Mole weight: 323.4. | |
| Neoline | Neoline isolated from the roots of Aconitum brachypodum Diels. Alternative Names: Bullatine B;Aconitane-1,8,14-triol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-, (1-alpha,6-alpha,14-alpha,16-beta)-;Dideacetyldelphisine. Grades: >=98%. CAS No. 466-26-2. Molecular formula: C24H39NO6. Mole weight: 337.57. | |
| Neoprzewaquinone A | Neoprzewaquinone A isolated from the roots of Salvia miltiorrhiza. Alternative Names: Neoprzewaquine A. Grades: 0.985. CAS No. 630057-39-5. Molecular formula: C36H28O6. Mole weight: 556.6. | |
| Neorauflavane | Neorauflavane is a natural flavonoid found in the herbs herbs of Flemingia macrophylla. Alternative Names: 4-[(R)-4,8-Dihydro-5-methoxy-8,8-dimethyl-2H,3H-benzo[1,2-b:5,4-b']dipyran-3-yl]-1,3-benzenediol. Grades: >95%. CAS No. 53734-74-0. Molecular formula: C21H22O5. Mole weight: 354.4. | |
| Neosophoramine | Neosophoramine comes from the herbs of Sophora alopecuroidos L. Alternative Names: Azacycloundecane-2,9-dione,11,11-dimethyl; 11,11-dimethyl-1-azacycloundecane-2,9-dione; 11,12,13,14-tetradehydro-matridin-15-one. Grades: 0.98. CAS No. 52932-74-8. Molecular formula: C15H20N2O. Mole weight: 244.3. | |
| Neostenine | Neostenine is a natural alkaloid isolated from the roots of Stemona sessilifolia. Alternative Names: (7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyldodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one. Grades: >97%. CAS No. 477953-07-4. Molecular formula: C17H27NO2. Mole weight: 277.4. | |
| Neotripterifordin | Neotripterifordinl is extracted from the roots of Tripterygium wilfordii. It displays potent anti-HIV replication activity with an EC50 value of 25 nM in H9 lymphocyte cells. Alternative Names: Neotripterifordin;149249-32-1;(1R,2R,5S,6R,8S,11R,12R)-6-hydroxy-6,12-dimethyl-14-oxapentacyclo[10.3.3.15,8.01,11.02,8]nonadecan-15-one. Grades: 98.5%. CAS No. 149249-32-1. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| Neotuberostemone | Neotuberostemonone is a natural alkaloid found in the roots of Stemona japonica. Alternative Names: (1R,2R,3S,6R,7S,10S)-2-Ethyl-6-methyl-10-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]-4-oxa-11-azatricyclo[9.4.1.03,7]hexadecane-5,8,16-trione. Grades: >98%. CAS No. 954379-68-1. Molecular formula: C22H31NO6. Mole weight: 405.5. | |
| Neotuberostemonine | Neotuberostemonine, a natural alkaloid found in the roots of Stemona tuberosa, has the activity of antitussive. Uses: Antitussive. Alternative Names: neotuberostemonine; 143120-46-1; CHEBI:69386; (1S,3S,9R,10R,11R,14S,15R,16R)-10-ethyl-14-methyl-3-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-12-oxa-4-azatetracyclo[7.6.1.04,16.011,15]hexadecan-13-one; C22H33NO4. Grades: >98%. CAS No. 143120-46-1. Molecular formula: C22H33NO4. Mole weight: 375.5. | |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine / noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine / noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Alternative Names: N6022; N 6022; N-6022; Nepicastat hydrochloride; (S)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride; Nepicastat (hydrochloride); UNII-3WK068D17I. Grades: >98%. CAS No. 170151-24-3. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. | |
| Neranic acid | Neranic acid. CAS No. 4613-38-1. | |
| Neratinib | Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Alternative Names: 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[[3-Chloro-4-((pyridin-2-yl)methoxy)phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2-butenamide; HKI 272; HKI-272; HKI272; PB-272; PB 272; PB 272. Grades: >98%. CAS No. 698387-09-6. Molecular formula: C30H29ClN6O3. Mole weight: 557.04. | |
| Neritaloside | Neritaloside is isolated from the herbs of Nerium indicum Mill. It exhibits central nervous system depressant activity in mic. Alternative Names: 16-Acetylstrospeside; Strospeside, 16-acetate; Card-20(22)-enolide, 16-(acetyloxy)-3-((6-deoxy-3-O-methyl-beta-D-galactopyranosyl)oxy)-14-hydroxy-, (3-beta,5-beta,16-beta)-. Grades: 95%. CAS No. 465-13-4. Molecular formula: C32H48O10. Mole weight: 592.73. | |
| Netarsudil hydrochloride | Netarsudil is a ROCK inhibitor and is approved for the treatment of glaucoma. Alternative Names: AR-13324 hydrochloride; Netarsudil dihydrochloride; [4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate dihydrochloride. Grades: >98%. CAS No. 1253952-02-1. Molecular formula: C28H29Cl2N3O3. Mole weight: 526.458. | |
| Netarsudil Mesylate | Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. CAS No. 1422144-42-0. Molecular formula: C30H35N3O9S2. Mole weight: 645.742. | |
| N-Ethanone Oxcarbazepine | An impurity of Oxcarbazepine which is used as an anticonvulsant by slowing abnormal nerve impulses in the brain. Alternative Names: Oxcarbazepine Related Compound B; Oxcarbazepine Impurity 003. Grades: 95%. Molecular formula: C17H14N2O3. Mole weight: 294.30. | |
| N-Ethyl Esmolol HCl | N-Ethyl Esmolol HCl is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Alternative Names: methyl 3-(4-(3-(ethylamino)-2-hydroxypropoxy)phenyl)propanoate, hydrochloride (1:1). Grades: 98%. Molecular formula: C15H24ClNO4. Mole weight: 317.81. | |
| Netupitant | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Alternative Names: AGE94200; AGE-94200; AGE 94200;Ro 67-3189; Ro-67-3189; Ro67-3189; CHEBI441603; CID6451149; D05152; UNII-7732P08TIR, CHEMBL206253, AG-E-94200, Netupitant. Grades: >98%. CAS No. 290297-26-6. Molecular formula: C30H32F6N4O. Mole weight: 578.603. | |
| Neuromedin U-23 (rat) trifluoroacetate | Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. Neuromedin U regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function, and also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. Alternative Names: L-Tyrosyl-L-lysyl-L-valyl-L-asparaginyl-L-α-glutamyl-L-tyrosyl-L-glutaminylglycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-serylglycylglycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide trifluoroacetate; Rat neuromedin U-23 trifluoroacetate. Grades: 98%. Molecular formula: C126H181N34F3O33. Mole weight: 2756.99. | |
| Neuromedin U-25 (human) trifluoroacetate salt | Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Alternative Names: Human Neuromedin U-25 Trifluoroacetate; NMU-25 Trifluoroacetate; L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt. Grades: 98%. Molecular formula: C141H203N41O38; XCF3COOH. Mole weight: 3080.37 (free base). | |
| NFF-3 TFA | NFF-3 TFA. | |
| N-Fluorobenzenesulfonimide | N-Fluorobenzenesulfonimide (CAS# 133745-75-2) is a mild electrophilic fluorinating reagent. Alternative Names: N-(benzenesulfonyl)-N-fluorobenzenesulfonamide. Grades: 95 %. CAS No. 133745-75-2. Molecular formula: C12H10FNO4S2. Mole weight: 315.34. | |
| N-Formyl Trimetazidine HCl | An impurity of Trimetazidine. Trimetazidine is a drug for angina pectoris. Alternative Names: 4-(2,3,4-Trimethoxybenzyl)-1-piperazine-carboxaldehyde hydrochloride; 4-(2,3,4-Trimethoxybenzyl)piperazine-1-carbaldehyde hydrochloride. CAS No. 879646-17-0. Molecular formula: C15H22N2O4.HCl. Mole weight: 330.81. | |
| NGP-555 | NGP-555 is a γ-secretase modulator that significantly lowers Aβ42 in cell cultures (9 nM) while increasing shorter forms of Aβ. NGP-555 has the potential for the treatment of Alzheimer's disease. Uses: Potential treatment of alzheimer's disease. Alternative Names: NGP-555; NGP 555; NGP555. N-(5-ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methylimidazol-1-yl)phenyl]-1,3-thiazol-2-amine. Grades: > 98%. CAS No. 1304630-27-0. Molecular formula: C23H23FN4S. Mole weight: 406.523. | |
| n-Heptyl acrylate | n-Heptyl acrylate. Alternative Names: 2-Propenoic acid, heptyl ester; Acrylic acid, heptyl ester; ENT 15748; Heptyl acrylate; heptylacrylate. CAS No. 2499-58-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| NI 57 | NI 57 is a BRPF bromodomain inhibitor. It is selective for BRPFs over other bromodomains. Alternative Names: NI-57; NI 57; NI57. 4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide. Grades: ≥98% by HPLC. CAS No. 1883548-89-7. Molecular formula: C19H17N3O4S. Mole weight: 383.42. | |
| Niazinin | Niazinin is a natural compound isolated from the leaves of Moringa oleifera Lam, showing antileishmanial activity against promastigotes of Leishmania donavani. Alternative Names: Niazinin A. Grades: 98.0%. CAS No. 147821-57-6. Molecular formula: C15H21NO6S. Mole weight: 343.39. | |
| NIBR189 | (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases. Alternative Names: NIBR-189; NIBR189. Grades: >98%. CAS No. 1599432-08-2. Molecular formula: C21H21BrN2O3. Mole weight: 429.31. | |
| Nicarbazin-[d8] | Nicarbazin-[d8] is a labelled form of Nicarbazin, an anti-parasitic drug for veterinary use. Alternative Names: Nicarbazin-d8; 1,3-Bis(4-nitrophenyl)urea-d8 4,6-Dimethyl-2(1H)-pyrimidinone. Grades: > 95%. Molecular formula: C13H2D8N4O5.C6H8N2O. Mole weight: 434.43. | |
| Niclosamide piperazine salt | Niclosamide piperazine salt. Alternative Names: Niclosamide Piperazine; 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide piperazine. CAS No. 34892-17-6. Molecular formula: C17H18Cl2N4O4. Mole weight: 413.255. | |
| Nicotiflorin | Nicotiflorin isolated from the herb of Carthamus tinctorius L. It has potential therapeutic effects on cerebral ischemic illness.And it has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats. Alternative Names: kaempferol-3-rutinoside; 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(4-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one. Grades: 0.985. CAS No. 17650-84-9. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Nifuratel | Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Uses: Antitrichomonal agents. Alternative Names: NF 113; SAP 113; NF113; SAP113; NF-113; SAP-113; Methylmercadone. Grades: >98%. CAS No. 4936-47-4. Molecular formula: C10H11N3O5S. Mole weight: 285.28. | |
| Nifuratel Impurity 2 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Alternative Names: Nifuratel Impurity 2 (Mixture of Diastereomers). Grades: 95%. CAS No. 1445990-09-9. Molecular formula: C10H11N3O6S. Mole weight: 301.28. | |
| Nifuratel Impurity 4 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Grades: 95%. CAS No. 41359-15-3. Molecular formula: C9H9N3O6. Mole weight: 255.18. | |
| Nifuratel Impurity 5 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Alternative Names: Nifuratel impurity 003. Grades: 95%. Molecular formula: C10H11N3O6S. Mole weight: 301.28. | |
| Nifuratel Impurity 6 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Alternative Names: 3-Amino-5-((methylthio)methyl)oxazolidin-2-one; 3-amino-5-(methylsulfanylmethyl)-1,3-oxazolidin-2-one; 2-Oxazolidinone,3-amino-5-[(methylthio)methyl]-; EINECS 247-064-8; DTXSID40948417; CS-0165799; 3-Amino-5-methylmercaptomethyl-2-oxazolidinone; 3-AMINO-5-[(METHYLSULFANYL)METHYL]-1,3-OXAZOLIDIN-2-ONE; 3-amino-5-((methylthio)methyl)oxazolidin-2-one? (Nifuratel Impurity pound(c). Grades: 95%. CAS No. 25517-72-0. Molecular formula: C5H10N2O2S. Mole weight: 162.21. | |
| Nifuroxazide EP Impurity D | An impurity of Nifuroxazide, which is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. Alternative Names: 5-Nitro-2-furfuraldazine; 5-Nitro-2-furancarboxaldehyde (E,E)-(5-Nitro-2-furanyl)methylene]hydrazone; USP Nitrofurazone Related Compound A. Grades: > 95%. CAS No. 112537-96-9. Molecular formula: C10H6N4O6. Mole weight: 278.18. | |
| Nigakihemiacetal B | Nigakihemiacetal B is found in the barks of Ailanthus altissima (Mill.) Swingle. Alternative Names: Neoquassine; Neoquassin; Simalikahemiacetal A. Grades: > 95%. CAS No. 76-77-7. Molecular formula: C22H30O6. Mole weight: 390.47. | |
| NIK SMI1 | NIK SMI1 is a potent and selective NF-κB inducing kinase (NIK) inhibitor. Alternative Names: (R)-6-(3-((3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide. CAS No. 1660114-31-7. Molecular formula: C20H19N3O4. Mole weight: 365.4. | |
| Niloticin | Niloticin, isolated from the barks of Phellodendron chinense, presented 83.2% ovicidal activity at 2ppm concentration after 120h post treatment and Niloticin exhibited significant growth disruption and morphological deformities at sub lethal concentrations against Ae. Alternative Names: (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one. Grades: >98%. CAS No. 115404-57-4. Molecular formula: C30H48O3. Mole weight: 456.7. | |
| Nilotinib EP Impurity H | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 40 nM. Alternative Names: Nilotinib Regio Isomer; 4-Methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: 95%. CAS No. 641571-15-5. Molecular formula: C28H22F3N7O. Mole weight: 529.53. | |
| Nilutamide | Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Uses: Antineoplastic agents. Alternative Names: Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. Grades: >98%. CAS No. 63612-50-0. Molecular formula: C12H10F3N3O4. Mole weight: 317.224. | |
| Nilutamide-[d6] | Nilutamide-[d6] is a labelled Nilutamide. Nilutamide is a nonsteroidal antiandrogen used for prostate cancer therapy. Alternative Names: 5,5-(Dimethyl-d6)-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedion; 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-(dimethyl-d6)imidazoline-2,5-dione; Anandron-d6; Nilandron-d6; Nilandrone-d6; RU 23908-d6; RU 23908-10-d6. Grades: >95%. CAS No. 1189477-66-4. Molecular formula: C12H4D6F3N3O4. Mole weight: 323.26. | |
| Nimesulide Impurity E | An impurity of Nimesulide, which is a selective COX-7 inhibitor. Alternative Names: N-(Methylsulfonyl)-4-(desnitro) Nimesulide; N-(Methylsulfonyl)-N-(2-phenoxyphenyl)methanesulfonamide. Grades: > 95%. CAS No. 905858-63-1. Molecular formula: C14H15NO5S2. Mole weight: 341.41. | |
| Nimesulide Impurity F | An impurity of Nimesulide, which is a selective COX-5 inhibitor. Alternative Names: N-Methylsulfonyl Nimesulide; N-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide; N-(Methylsulfonyl)-4'-nitro-2'-phenoxymethanesulfonanilide. Grades: > 95%. CAS No. 51765-72-1. Molecular formula: C14H14N2O7S2. Mole weight: 386.4. | |
| Nimodipine | Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine decreases intracellular free Ca2+, Beclin-1 and autophagy. Uses: Antihypertensive agents. Alternative Names: Nimotop; Periplum; Admon; LY127809; LY 127809; LY-127809; BAY E 9736, BAY-E-9736, BAYE9736. Grades: >98%. CAS No. 66085-59-4. Molecular formula: C21H26N2O7. Mole weight: 418.44. | |
| Nintedanib (Intedanib) | Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Alternative Names: Vargatef; BIBF-1120; BIBF 1120; BIBF1120; Intedanib. Grades: ≥98%. CAS No. 656247-17-5. Molecular formula: C31H33N5O4. Mole weight: 539.62. | |
| Nintedanib Piperazine Dimer Impurity | Nintedanib Piperazine Dimer Impurity. CAS No. 2410284-90-9. | |
| Nitazoxanide-[d4] | The isotope labelled Nitazoxanide which could used as an anthelmintic agent. Uses: The isotope labelled nitazoxanide. Alternative Names: 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide-d4; Alinia-d4; BRN 1225475-d4; Cryptaz-d4; DRG 0242-d4; N-(5-Nitro-2-thiazolyl)salicylamide-d4 Acetate Ester; Nitacure-d4; Nitarid-d4; Nitazoxanida-d4; Nixide-d4; Nixoran-d4; Nizonide-d4. Grades: >98%. CAS No. 1246819-17-9. Molecular formula: C12H5D4N3O5S. Mole weight: 311.31. | |
| Nitidine chloride | Nitidine chloride, that comes from the roots of Zanthoxylum nitidum (Roxb.) DC, could be developed as a potential anticancer agent to renal cancer and worthy of further studies. Nitidine chloride inhibited the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identified efficacy in vivo in a mouse model of HCC. Uses: Anticancer / anti-metastasis. Alternative Names: 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium chloride; [1,3]Dioxolo[4,5]benzo[1,2-c]phenanthridinium, 2,3-; dimethoxy-12-methyl-,chloride; Angolinine; 2,3-DiMethoxy-12-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride. Grades: >98%. CAS No. 13063-04-2. Molecular formula: C21H18ClNO4. Mole weight: 383.83. | |
| Nitrofurazone-[13C,15N2] | Nitrofurazone-[13C,15N2] is the labelled analogue of Nitrofurazone, which is an antimicrobial agent commonly used in the topical antibiotic ointment. Alternative Names: Nitrofurazone-13C,15N2; 5-Nitro-furan-2-carbaldehyde semicarbazone-1,2-15N2,13C; 2-[(5-Nitro-2-furanyl)methylene]hydrazinecarboxamide-13C,15N2; (5-Nitro-2-furfurylidenamino)urea-13C,15N2; 1-(5-Nitro-2-furfurylidene)semicarbazide-13C,15N2; Aldomycin-13C,15N2; Alfucin-13C,15N2; Amifur-13C,15N2; Babrocid-13C,15N2; Chemofuran-13C,15N2; Coxistat-13C,15N2; Furesol-13C,15N2; Mammex-13C,15N2. Grades: 95% by HPLC; 98% atom 13C; 98% atom 15N. CAS No. 1217220-85-3. Molecular formula: C5[13C]H6N2[15N]2O4. Mole weight: 201.12. | |
| Nitroso-sertraline-[d3] (cis racemic mixture) | Nitroso-sertraline-[d3] (cis racemic mixture) is a labelled analogue of nitroso-sertraline. Nitroso-sertraline is undergoing extensive first-pass metabolism by cytochrome P450 and selectively inhibits the reuptake of serotonin at the presynaptic neuronal membrane that is used to treat the major depressive disorder, a social anxiety disorder. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide; Nitroso-sertraline-d3 (cis racemic mixture). Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. | |
| Nizatidine-[d3] | Nizatidine-[d3] is the labelled analogue of Nizatidine, which is a histamine H2 receptor antagonist with IC50 of 0. 9 nM, also inhibits AChE with IC50 of 6. 7 μM. Alternative Names: Nizatidine D3; N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-(methyl-d3)-2-nitro-1,1-ethenediamine. Grades: 95% by HPLC; 95% atom D. CAS No. 1246833-99-7. Molecular formula: C12H18D3N5O2S2. Mole weight: 334.48. | |
| Nizatidine Sulfoxide-[d3] | Nizatidine Sulfoxide-[d3] is the labelled analogue of Nizatidine Sulfoxide, which is an impurity of Nizatidine. Nizatidine is a histamine H2 receptor antagonist. Alternative Names: Nizatidine-d3 Sulfoxide; N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]sulfinyl]ethyl]-N'-(methyl-d3)-2-nitro-1,1-ethenediamine; Nizatidine EP Impurity C-d3. CAS No. 1795136-43-4. Molecular formula: C12H18D3N5O3S2. Mole weight: 350.48. | |
| N-Methoxyanhydrovobasinediol | N-Methoxyanhydrovobasinediol is a natural alkaloid found in the herbs of Gelsemium elegans. Alternative Names: N-Methoxyanhydrovobasinediol; 125180-42-9; (1S,12S,15Z,16S)-15-ethylidene-3-methoxy-13-methyl-19-oxa-3,13-diazapentacyclo[14.3.1.02,10.04,9.012,17]icosa-2(10),4,6,8-tetraene. Grades: >98%. CAS No. 125180-42-9. Molecular formula: C21H26N2O2. Mole weight: 338.5. | |
| N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: Vonoprazan Impurity 31 Fumarate; Vonoprazan Impurity U8(Fumarate). Grades: 95%. CAS No. 928325-82-0. Molecular formula: C21H21N3O6S. Mole weight: 443.47. | |
| N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Alternative Names: N-methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide; N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide. CAS No. 1139453-98-7. Molecular formula: C14H20N4O3. Mole weight: 292.33. | |
| N-Methyl-3,3-diphenylpropylamine | N-Methyl-3,3-Diphenylpropylamine is an intriguing molecule that exhibits remarkable effects on the central nervous system, acting as a highly potent stimulant. Its usage in research has proven valuable in understanding the transport and regulatory mechanisms of dopamine and norepinephrine. Moreover, its therapeutic potential in addressing complex neurological disorders such as attention deficit hyperactivity disorder and narcolepsy bears considerable promise. Alternative Names: (3,3-diphenylpropyl)methylamine; N-METHYL-3,3-DIPHENYLPROPYLAMINE; 3,3-Diphenyl-N-Methylpropylamine; Methyl(3,3-diphenylpropyl)amine; N-Methyl-3,3-diphenyl-1-propanamine; N-Methyl-γ-phenylbenzenepropan-1-amine. Grades: 95%. CAS No. 28075-29-8. Molecular formula: C16H19N. Mole weight: 225.33. | |
| N-Methyl-4-(p-formylstyryl)pyridinium methylsulfate | N-Methyl-4-(p-formylstyryl)pyridinium methylsulfate. Alternative Names: Pyridinium, 4-[2-(4-formylphenyl)ethenyl]-1-methyl-, methyl sulfate (1:1); 1-Methyl-4-(4-formylstyryl)pyridinium methyl sulfate; 4-[2-(4-Formylphenyl)ethenyl]-1-methylpyridinium methyl sulfate; N-Methyl-4-(p-formylstyryl)pyridinium monomethyl sulfate; SBQ. Grades: ≥95%. CAS No. 74401-04-0. Molecular formula: C15H14NO.CH3O4S. Mole weight: 335.37. | |
| N-Methyl Duloxetine | An impurity of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Alternative Names: (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine; (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine. Grades: 95%. CAS No. 132335-46-7. Molecular formula: C19H21NOS. Mole weight: 311.44. | |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Alternative Names: N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide; 1038972-16-5; CS-0011633; N-Methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide (Nintedanib Impurity). CAS No. 1038972-16-5. Molecular formula: C13H18N4O3. Mole weight: 278.31. | |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide hydrochloride | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. CAS No. 2037385-84-3. Molecular formula: C13H19ClN4O3. Mole weight: 314.77. | |
| N-Methyl Omeprazole Impurity 1 | N-Methyl Omeprazole Impurity 1 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Alternative Names: N'-Methyl Omeprazole; Omeprazole N-Methyl 5-Methoxy Analog; (5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-1H-benzimidazole; N-Methyl Omeprazole (Mixture of Isomers). Grades: > 95%. CAS No. 89352-76-1. Molecular formula: C18H21N3O3S. Mole weight: 359.44. | |
| N-Methyloxamic acid | N-Methyloxamic acid. CAS No. 29262-58-6. | |
| NMS-1286937 | NMS1286937, also know as NMS-P937, is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor NMS-1286937 selectively inhibits PLK1, inducing selective G2/M cell-cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell-cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1 inhibition may result in the inhibition of proliferation in PLK1-overexpressing tumor cells. PLK1 is a serine / threonine protein kinase crucial in the regulation of mitosis. Uses: Protein kinase inhibitors. Alternative Names: PCM-075; PCM 075; PCM075; NMS1286937; NMS 1286937; NMS-1286937; NMS-P937; NMS-P-937; NMS-P 937; Onvansertib. Grades: >98%. CAS No. 1034616-18-6. Molecular formula: C24H27F3N8O3. Mole weight: 532.53. | |
| N,N'-bis-(2-Chloroethyl)urea | N,N'-bis-(2-Chloroethyl)urea is an indispensable compound in the field of biomedicine manifesting remarkable cytotoxic characteristics. Its application extends to diverse cancer types, encompassing lymphoma, leukemia and solid tumors, owing to its potent chemotherapeutic attributes. Alternative Names: 1,3-bis(2-chloroethyl)urea; 1,3-Bis(2-chloroethyl)urea; 2214-72-4; N,N'-Bis(2-chloroethyl)urea; VBWBRZHAGLZNST-UHFFFAOYSA-N; Urea,N,N'-bis(2-chloroethyl)-. Grades: 95%. CAS No. 2214-72-4. Molecular formula: C5H10Cl2N2O. Mole weight: 185.053. | |
| N,N-Bis(2-hydroxyethyl)ethylenediamine | N,N-Bis(2-hydroxyethyl)ethylenediamine. CAS No. 3197-6-6. | |
| N,N-diethyl-2-((6-methylpyridin-2-yl)methylene)hydrazinecarbothioamide | N,N-diethyl-2-((6-methylpyridin-2-yl)methylene)hydrazinecarbothioamide, a chemically-complex compound, is gaining recognition in biomedicine as a viable drug candidate for treating a range of ailments. Notably, research suggests that it possesses considerable anti-inflammatory, analgesic, and antioxidant activity that could hold promise in combatting conditions such as arthritis and other inflammatory disorders. Nevertheless, comprehensive studies are necessary to ascertain its optimal therapeutic capacity. Alternative Names: Hydrazinecarbothioamide, N,N-diethyl-2-[(6-methyl-2-pyridinyl)methylene]-. Grades: ≥98%. CAS No. 210700-64-4. Molecular formula: C12H18N4S. Mole weight: 250.36. | |
| N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine | N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine, also called 2-Ethylaminoatrazine, under the IUPAC name 2-Ethylaminoatrazine, can be used as insecticide and herbicide. Uses: Insecticide; herbicide. Alternative Names: 4-N,6-N-diethyl-2-N-propan-2-yl-1,3,5-triazine-2,4,6-triamine; 30360-19-1; N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine; 2,4-Bis(ethylamino)-6-isoproylamino-1,3,5-triazine; EINECS 250-146-6; 2-Ethylaminoatrazine; 2-(Ethylamino)atrazine; AC1L1SY9; SCHEMBL11452149; ZINC2011064; Melamine, N2,N4-diethyl-N6-isopropyl-; HE048494; N2,N4-DIETHYL-N6-ISOPROPYLMELAMINE; 3B1-004129; 4-N,6-N-diethyl-2-N-propan-2-yl-1,3,5-triazine-2,4,6-triamine; N N'-DIETHYL-N''-ISOPROPYL-1 3 5-TRIAZINE-2 4 6-TRIAMINE; N2,N4-diethyl-N6-(propan-2-yl)-1,3,5-triazine-2,4,6-triamine. Grades: ≥ 95.0%. CAS No. 30360-19-1. Molecular formula: C10H20N6. Mole weight: 224.31. | |
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