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LOXO-101 sulfate
The sulfate salt form of LOXO-101, also called Larotrectinib, which is an ATP-competitive inhibitor of tropomyosin receptor kinases. It was approved by FDA for the treatment of metastatic solid tumors. Alternative Names: LOXO-101 sulfate; LOXO 101 sulfate; LOXO101 sulfate; Larotrectinib sulfate; (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide sulfate. Grades: >95%. CAS No. 1223405-08-0. Molecular formula: C21H24F2N6O6S. Mole weight: 526.51.
Loxoprofen Ring-opening Impurity
Loxoprofen Ring-opening Impurity is a degradation product of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Alternative Names: 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid; 2-[4-(2-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid. Grades: > 95%. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3.
L-Phe(1)-Octreotide trifluoroacetate salt
L-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: H-L-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7). Grades: 95%.
LRRK2-IN-1
LRRK2-IN-1 is a benzodiazepine based derivative and is known as a selective inhibitor of the Parkinson's disease kinase LRRK2. Alternative Names: LRRK2-IN-1; LRRK2-IN 1; LRRK2-IN1. Grades: >98%. CAS No. 1234480-84-2. Molecular formula: C31H38N8O3. Mole weight: 570.69.
LS-tetrasaccharide a sodium salt
LS-tetrasaccharide a sodium salt.
LS-tetrasaccharide c sodium salt
LS-tetrasaccharide c sodium salt.
L-Threoninol(Ac)-8-Octreotide trifluoroacetate salt
Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7); O-Acetyl Octreotide trifluoroacetate salt. Grades: 95%.
LTI-291
LTI-291 is a glucocerebrosidase (Gcase) activator for the treatment of Parkinson's disease (PD). Alternative Names: LTI-291; LTI 291; LTI291. 5,7-dimethyl-N-(4-pentoxycyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS No. 1919820-28-2. Molecular formula: C20H30N4O2. Mole weight: 358.486.
Lu AE58054
Lu AE58054 is a selective and high affinity 5-HT6 receptor antagonist as a promising treatment for cognitive disorders. Uses: 5-ht(6)r antagonist. Alternative Names: 2-(6-fluoro-1H-indol-3-yl)-N-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)ethanamine; Lu AE58054; Lu AE-58054; Lu AE 58054; Idalopirdine; Iladopirdine. Grades: ≥98%. CAS No. 467459-31-0. Molecular formula: C20H19F5N2O. Mole weight: 398.37.
Lu AE58054 HCl salt
Lu AE58054 hydrochloride is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM. Alternative Names: Lu AE 58054 Hydrochloride. Grades: 0.98. CAS No. 467458-02-2. Molecular formula: C20H20ClF5N2O. Mole weight: 434.835.
Lubiprostone
Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation. Alternative Names: Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid; RU 0211. Grades: ≥98%. CAS No. 136790-76-6. Molecular formula: C20H32F2O5. Mole weight: 390.47.
Lucidenic acid A
Lucidenic acid A, a naturally occurring compound found in Ganoderma lucidum fruiting bodies, displays immense therapeutic potential. It exhibits anti-inflammatory, anti-tumor, and anti-diabetic properties as evidenced by various studies. Additionally, it significantly impacts physiological parameters such as blood pressure, cholesterol, and blood sugar. The multifaceted activities of Lucidenic acid A render it an ideal candidate for treating chronic inflammatory diseases, diabetes, and cancer. Alternative Names: lucidenic acid A; 95311-94-7; LucidenicacidA; Lucideric acid A; (4R)-4-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid; CHEMBL460969; SCHEMBL6522668; CHEBI:172690; DTXSID401316662; HY-N6862; BDBM50356926; AKOS037515140; AC-34115; MS-28395; CS-0027808; D85042; 7beta-hydroxy-4,4,14alpha-trimethyl-3,11,15-trioxo-5alpha-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-94-7. Molecular formula: C27H38O6. Mole weight: 458.59.
Lucidenic acid B
Lucidenic acid B, an organic compound hailing from Ganoderma lucidum, is praised for its multifaceted biomedical properties. From combating neoplasms to alleviating inflammations, this natural triterpenoid holds great promise in treating debilitating conditions such as breast and prostate cancers and an array of inflammatory disorders. Alternative Names: Lucidenic acid B; (5alpha,7beta,12beta)-7,12-Dihydroxy-4,4,14-trimethyl-3,11,15-trioxo-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-95-8. Molecular formula: C27H38O7. Mole weight: 474.58642.
Lucidenic acid C
Lucidenic acid C, an organic compound derived from the fungus Ganoderma lucidum, exhibits multifaceted pharmacological actions such as antioxidant, anti-inflammatory, immunomodulatory, and anticancer properties. Novel studies have elucidated that this naturally occurring triterpene exhibits profound inhibition of malignancy development and metastasis in cancer cells. The promising therapeutic potential of lucidenic acid C extends beyond oncology, offering a plethora of therapeutic applications in diverse pathological conditions. Alternative Names: Lucidenic acid C; (3beta,5alpha,7beta,12beta)-3,7,12-Trihydroxy-4,4,14-trimethyl-11,15-dioxo-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-96-9. Molecular formula: C27H40O7. Mole weight: 476.6023.
Lucidenic acid D
Lucidenic acid D, a triterpenoid compound, is extracted from Ganoderma lucidum and is reported to be endowed with multifarious biological activities, such as anti-cancer, anti-inflammatory, and antioxidant properties. With its remarkable potential to stimulate apoptosis in cancer cells, lucidenic acid D stands out as an effective therapeutic candidate for combating cancer and other ailments. Alternative Names: Lucidenic acid D; Lucidenic acid D; 298665-16-8; LucidenicacidD; UNII-4C2000605T. Grades: >98%. CAS No. 98665-16-8. Molecular formula: C29H38O8. Mole weight: 514.61.
Lucidenic acid E
Lucidenic acid E, a triterpenoid derived from Ganoderma lucidum, exhibits potent anti-inflammatory, anti-tumor and anti-diabetic activities. Notably, it has demonstrated the ability to impede in vitro cancer cell growth, indicating its potential therapeutic value. Its hepatoprotective and antioxidant effects further increase the promise of lucidenic acid E in the treatment of liver ailments. Such multifaceted properties of this natural compound highlight its potential in the development of novel therapies. Alternative Names: Lucidenic Acid E2; Lucidenic acid E. Grades: >98%. CAS No. 98665-17-9. Molecular formula: C29H40O8. Mole weight: 516.631.
Lucidenic acid LM1
Lucidenic acid LM1, a triterpenoid compound, is obtained from medicinal fungi that are fit for consumption. Numerous biological activities have been ascertained to be associated with this compound such as anti-cancer, anti-inflammatory, and anti-fibrotic effects. The inhibition of human liver cancer and breast cancer cells are among the effects of Lucidenic acid LM1, which suggests its potential candidacy for the development of new anti-cancer drugs. Alternative Names: (3beta,5alpha,7beta)-3,7-dihydroxy-4,4,14-trimethyl-11,15-dioxochol-8-en-24-oic acid. Grades: >98%. CAS No. 364622-33-3. Molecular formula: C27H40O6. Mole weight: 460.6.
Lucidin
Lucidin is a natural component of Rubia tinctorum L. It exhibits antibacterial activity. Alternative Names: Henine; NSC 30546; NSC30546; NSC-30546. Grades: >98%. CAS No. 478-08-0. Molecular formula: C15H10O5. Mole weight: 270.24.
Lumefantrine-[d9]
Lumefantrine-[d9] is the labelled analogue of Lumefantrine, which Inhibits hemozoin formation, used as antimalarial. Alternative Names: Lumefantrine D9. Grades: 98% by HPLC; 98% atom D. CAS No. 2477594-24-2. Molecular formula: C30H23D9Cl3NO. Mole weight: 538.00.
Luminol sodium salt
Luminol sodium salt is a reagent used in chemiluminescence analysis of metal cations, blood and glucococorticoids. Alternative Names: 5-Amino-2,3-dihydrophthalazine-1,4-dione, sodium salt; Luminol monosodium salt; 3-Aminophthalhydrazide monosodium salt. Grades: ≥98%. CAS No. 20666-12-0. Molecular formula: C8H6N3NaO2. Mole weight: 199.14.
Lup-20(29)-en-28-oic acid, 3-[ D-glucopyranosyl(1→4)[ L-rhamnopyranosyl) (1→2)-L-arabinopyranosyl]oxy], (3,4)-) is extracted from Pulsatilla chinensis (Bunge) Regel. Alternative Names: Betulinic acid 3beta-O-alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranoside. Grades: >98%. CAS No. 848784-87-2. Molecular formula: C47H76O16. Mole weight: 897.1.
Lup-20(29)-ene-3α,23-diol
Lup-20(29)-ene-3α,23-diol isolated from the barks of Glochidion macrophyllum. Uses: Anti-hiv activity. Alternative Names: (1R,3aR,5aR,5bR,7aR,8R,9R,11aR,11bR,13aR,13bR)-8-(hydroxymethyl)-3a,5a,5b,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol. Grades: 0.985. CAS No. 32451-85-7. Molecular formula: C30H50O2. Mole weight: 442.7.
Lusutrombopag
Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist. It acts selectively on the human TPO receptor and activates signal transduction pathways and thereby increases platelet levels. It was developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. It has been listed. Uses: Lusutrombopag was used for chronic liver disease (cld) patients with thrombocytopenia prior to elective invasive surgery. Alternative Names: S-888711; S 888711; S888711; (E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid. Grades: >98%. CAS No. 1110766-97-6. Molecular formula: C29H32Cl2N2O5S. Mole weight: 591.54.
Luteolin-3-O-beta-D-glucuronide
Luteolin-3-O-beta-D-glucuronide is a flavonoid isolated from Rosmarinus officinalis. Alternative Names: Luteolin 3'-o-glucuronide; Luteolin 3'-glucuronide. Grades: 98%. CAS No. 53527-42-7. Molecular formula: C21H18O12. Mole weight: 462.4.
Luteolin 5-methyl ether
Luteolin 5-methyl ether, a flavone compound of natural origin with potent pharmacological effects, can be obtained from a variety of plant species. Its therapeutic potential encompasses a broad spectrum of health conditions such as cancer, cardiovascular diseases, diabetes, and neurodegenerative disorders, primarily due to its antioxidant, anti-inflammatory, and antitumor properties. The inspiring results from studies conducted in this realm suggest that Luteolin 5-methyl ether is a promising candidate for the development of novel therapeutic agents. Alternative Names: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-. Grades: 98.0%. CAS No. 58115-29-0. Molecular formula: C16H12O6. Mole weight: 300.27.
Luteone
Luteone is a natural flavonoid isolated from the herbs of Erythrina variegata Linn. Alternative Names: 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 41743-56-0. Molecular formula: C20H18O6. Mole weight: 354.4.
Luvangetin
Luvangetin is a coumarin isolated from the stem bark of Zanthoxylum ailanthoides. Luvangetin exhibits inhibition against superoxide anion (O2 -) generation and elastase release by human neutrophils in response to fMLP/CB. Alternative Names: 10-methoxy-2,2-dimethylpyrano[3,2-g]chromen-8-one. Grades: 99.0%. CAS No. 483-92-1. Molecular formula: C15H14O4. Mole weight: 258.273.
Lvguidingan
Lvguidingan is an antiepileptic drug. Alternative Names: Anticonvulsant 7903; N-(Butan-2-yl)-3-(3,4-dichlorophenyl)prop-2-enamide; 3,4-Dichlorophenyl propenylisobutylamide; 3,4-Dichlorophenylpropenoyl isobutylamide. CAS No. 82351-05-1. Molecular formula: C13H15Cl2NO. Mole weight: 272.169.
LX-4211
LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. Uses: Sodium-glucose transporter 2 inhibitors. Alternative Names: LX4211; LX-4211; LX 4211; Sotagliflozin. Grades: >98%. CAS No. 1018899-04-1. Molecular formula: C21H25ClO5S. Mole weight: 424.94.
LY2090314
LY2090314 is a potent GSK3 inhibitor with antiproliferative activity. It was shown to promote differentiation of intestinal progenitor cells from human iPSCs. Alternative Names: LY-2090314; 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione. Grades: >98%. CAS No. 603288-22-8. Molecular formula: C28H25FN6O3. Mole weight: 512.545.
LY2228820 dimesylate
LY2228820 dimesylate is the salt form of LY2228820, a tri-substituted imidazole derivative and p38α and β MAPK inhibitor. LY2228820 inhibits tumor growth in various cancer models. Alternative Names: Ralimetinib Mesylate; Ralimetinib dimesylate; 5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine mesylate. Grades: >98%. CAS No. 862507-23-1. Molecular formula: C26H37FN6O6S2. Mole weight: 612.74.
LY-2562175
LY2562175 is a potent and selective FXR agonist in vitro. It has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species. It was developed by Eli Lilly and Company and in clinic phase 1 trials with no progress. Uses: Ly2562175 has robust lipid modulating properties, lowering ldl and triglycerides while raising hdl in preclinical species. Alternative Names: LY2562175; LY 2562175; LY-2562175;6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid. Grades: >98%. CAS No. 1103500-20-4. Molecular formula: C28H27Cl2N3O4. Mole weight: 540.44.
LY2784544
LY2784544 is a potent and selective JAK2 inhibitor (IC50 = 3 nM), and exhibits less potency against JAK3 (IC50 =48 nM). LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50 = 20 and 55 nM, respectively). It reduces JAK2V617F tumor cell burden with no effect on erythroid progenitor cells. Alternative Names: Gandotinib; LY-2784544; 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine. Grades: >98%. CAS No. 1229236-86-5. Molecular formula: C23H25ClFN7O. Mole weight: 469.949.
LY2795050
LY2795050, a κ-opioid Receptor antagonist, has been found to be effective in imaging KOR behaving as a PET tracer. IC50: 0.72 nM and 25.8 nM for κ-opioid Receptor and κ-opioid. Uses: Ly2795050 is a κ-opioid receptor antagonist that has been found to be effective in imaging kor behaving as a pet tracer. Alternative Names: LY2795050; LY 2795050; LY-2795050; (S)-LY2795050; UNII-71PAL357HO; CHEMBL1921842; 71PAL357HO; BDBM50358166. Grades: 98%. CAS No. 1346133-08-1. Molecular formula: C23H22ClN3O2. Mole weight: 407.89.
LY294002
LY294002 is a potent inhibitor of phosphoinositide PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively. Alternative Names: LY294002; LY-294002; LY 294002; 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; 2-morpholino-8-phenyl-4H-chromen-4-one. Grades: >98%. CAS No. 154447-36-6. Molecular formula: C19H17NO3. Mole weight: 307.349.
LY3009120
LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1. Alternative Names: LY3009120; LY-3009120; LY 3009120; DP4978; DP 4978; DP-4978. Grades: 98%. CAS No. 1454682-72-4. Molecular formula: C23H29FN6O. Mole weight: 424.51.
LY-364947
LY364947 is a selective inhibitor of TGF-β type-I receptor with potential anticancer activity. LY364947 inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3). Uses: Reprogramming. Alternative Names: LY364947; LY-364947; LY 364947; HTS 466284; HTS466284; HTS-466284. Grades: 98%. CAS No. 396129-53-6. Molecular formula: C17H12N4. Mole weight: 272.31.
LY404039
LY-404,039, also known as pomaglumetad, is an amino acid analog drug that acts as a highly selective agonist for the metabotropic glutamate receptor group II subtypes mGluR2 and mGluR3. Alternative Names: GW786034 HCl; LY-404039; LY 404039; LY404039; LY-404,039; LY404,039; LY 404,039; Pomaglumetad. Grades: >98%. CAS No. 635318-11-5. Molecular formula: C7H9NO6S. Mole weight: 235.22.
LY-411575
LY-411575, also known as LSN-411575, is a potent, cell-permeable γ-secretase inhibitor (IC50 = 0.078 nM/0.082 nM in membrane-assay/in cell-basedγ-secretase assays) and also inhibits Notch clevage (IC50 = 0.39 nM). Alternative Names: (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide; LY 411,575; LY 411575; LY411575; (S)-2-((S)-2-(3,5-Difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide. Grades: >98%. CAS No. 209984-57-6. Molecular formula: C26H23F2N3O4. Mole weight: 479.48.
LY-900009
LY-900009 is a small-molecule inhibitor of Notch signalling with IC50 value of 0.27 nM via selective inhibition of the γ-secretase protein. LY-900009 was developed as a candidate therapeutic drug against AD (IDENTITY trial), which failed in phase III trials. Uses: Gamma secretase inhibitors and modulators. Alternative Names: LY900009; LY-900009; LY 900009; (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]amino]-1-oxopropan-2-yl]butanamide. Grades: >98%. CAS No. 209984-68-9. Molecular formula: C23H27N3O4. Mole weight: 409.486.
Lycobetaine
Lycobetaine is a remarkable biomedical innovation engineered to efficaciously study intricate cardiovascular maladies. Harnessing the invaluable attributes derived from bountiful bionatural origins, Lycobetaine proficiently merges indispensable nutritive constituents with potent antioxidants. Alternative Names: Lycobetaine. Grades: >98%. CAS No. 72510-04-4. Molecular formula: C16H12NO3. Mole weight: 266.27.
Lycojaponicuminol C
Lycojaponicuminol C, an organic compound extracted from natural sources, possesses intriguing antitumor effects. Preclinical investigations have demonstrated its modulating capacity over the carcinogenic progression of various types of tumors, including breast and colon. The molecular mechanisms behind its cytotoxicity involve impeding malignant proliferation and provoking programmed cell death in cancer cells. Alternative Names: Lycojaponicuminol C; AKOS040763061; 1651839-34-7. Grades: 97.5%. CAS No. 1651839-34-7. Molecular formula: C29H48O4. Mole weight: 460.698.
Lyoniresinol
Lyoniresinol, a natural lignan isolated from the root of Vitex negundo,is one of the eight lignans purified from methanol which has robust tyrosinase inhibitory capacity. Lyoniresinol exhibits the activity of antioxidative, and it decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulates MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression, it can perhaps be incorporated into clinical dermatologic use as a skin lightening agent. Uses: Anti-melanogenic; anti-oxidant. Alternative Names: (1S)-1α-(3,5-Dimethoxy-4-hydroxyphenyl)-6,8-dimethoxy-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2β,3α-dimethanol. Grades: >98%. CAS No. 14464-90-5. Molecular formula: C22H28O8. Mole weight: 420.5.
Lys-Lys-Lys HCl
Lys-Lys-Lys is a cationic moiety that may be used in the construction of gene delivery vectors and DNA nanoparticles. Alternative Names: H-Lys-Lys-Lys-OH.HCl; Lys-Lys-Lys hydrochloride. Grades: ≥95%. Molecular formula: C18H39ClN6O4. Mole weight: 439.00.
m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt
m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt is a trinucleotide mRNA 5' cap analogs. m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt can be used for RNA synthesis in vitro. Alternative Names: CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG Ammonium; GAG(m6A) ammonium salt; m7Gppp(2'OMe,m6A)pG ammonium salt; m7Gpppm6AmpG ammonium salt. Grades: ≥98%. Molecular formula: C33H45N15O24P4 (free acid). Mole weight: 1159.69 (free acid).
Macamide Impurity 2
Macamide Impurity 2 is an indispensible natural compound extensively applied in the biomedical sector. Alternative Names: N-Benzyloleamide. Grades: >98%. CAS No. 883715-21-7. Molecular formula: C25H41NO. Mole weight: 371.6.
Machigline
Machigline is a phenolic oxoaporphine alkaloid isolated from Machilus macrantha. Grades: 97.0%. CAS No. 87264-30-0. Molecular formula: C18H11NO5. Mole weight: 321.289.
Macitentan
Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity. Uses: Endothelin a receptor antagonists. Alternative Names: ACT-064992; ACT064992; ACT 064992. Grades: > 95%. CAS No. 441798-33-0. Molecular formula: C19H20Br2N6O4S. Mole weight: 588.275.
Macitentan Dimer
It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Alternative Names: Macitentan Pyrimidine Dimer; N,N''-[1,2-Ethanediylbis[oxy[5-(4-bromophenyl)-6,4-pyrimidinediyl]]]bis[N'-propylsulfamide]; O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan. Grades: 95%. CAS No. 2089065-77-8. Molecular formula: C28H32Br2N8O6S2. Mole weight: 800.54.
Macrocarpal A
Macrocarpal A is a cytotoxic alkaloid isolated from the branch of Eucalyptus globulus. Uses: Antifouling activity; antibacterial activity. Alternative Names: 2,4,6-Trihydroxy-5-[(1R)-1-[(1aβ,4R,4aβ,7aα,7bβ)-1,1,4,7-tetramethyl-4β-hydroxydecahydro-1H-cyclopropa[e]azulene-7α-yl]-3-methylbutyl]isophthalaldehyde. Grades: 97.5%. CAS No. 132951-90-7. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal B
Macrocarpal B, which can be found in the branch of Eucalyptus globulus, shows antifouling activity. Uses: Antibacterial / antifouling. Alternative Names: 5-[(1S)-1-[(1aR,4R,4aR,7S,7aS,7bR)-4-hydroxy-1,1,4,7-tetramethyl-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde;1,3-Benzenedicarboxaldehyde, 5-[(1S)-1-[(1aR,4R,4aR,7S,7aS,7bR)-decahydro-4-hydroxy-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-. Grades: >98%. CAS No. 142698-60-0. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal J
Macrocarpal J is isolated from the branch of Eucalyptus globulus. Uses: Anti-bacterial activity. Alternative Names: 2,4,6-trihydroxy-5-[(1S)-1-[(4S)-4-hydroxy-6-(2-hydroxypropan-2-yl)-4,8a-dimethyl-1,2,3,4a,5,6,7,8-octahydronaphthalen-1-yl]-3-methylbutyl]benzene-1,3-dicarbaldehyde. Grades: > 95%. CAS No. 179603-47-5. Molecular formula: C28H42O7. Mole weight: 490.6.
Macrocarpal L
Macrocarpal L is isolated from the branch of Eucalyptus globulus. Alternative Names: 2,4,6-Trihydroxy-5-{(1R)-1-[(1aS,3aS,4S,7R,7aR,7bS)-7-hydroxy-1,1 ,3a,7-tetramethyldecahydro-1H-cyclopropa[a]naphthalen-4-yl]-3-met hylbutyl}isophthalaldehyde. Grades: 98%. CAS No. 327601-97-8. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal N
Macrocarpal N is isolated from the twigs of Eucalyptus globules Labill. Alternative Names: 5-[(1S)-1-{(1R,2R)-2-[(1R,3R)-2,2-Dimethyl-3-(3-oxobutyl)cyclopro pyl]-1-methyl-3-oxocyclopentyl}-3-methylbutyl]-2,4,6-trihydroxyis ophthalaldehyde. Grades: 97.5%. CAS No. 221899-21-4. Molecular formula: C28H38O7. Mole weight: 486.6.
Macrozamin
Macrozamin is a natural compound showing teratogenic carcinogenic, mutagenic and neurotoxic properties. Alternative Names: (2-Methyl-2-oxidodiazenyl)methyl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside; β-D-Glucopyranoside, (methyl-ONN-azoxy)methyl 6-O-β-D-xylopyranosyl-; NSC 44423; 1-Methyl-2-((((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)diazene 1-oxide. Grades: 98%. CAS No. 6327-93-1. Molecular formula: C13H24N2O11. Mole weight: 384.34.
MADB
It is a novel Trinder's reagent used as a water-soluble reagent for the determination of hydrogen peroxide by enzyme spectrophotometry, and is widely used in diagnostic detection and biochemical test. Alternative Names: N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt; Sodium 4,4'-((3,5-dimethylphenyl)azanediyl)bis(butane-1-sulfonate). Grades: ≥95%. CAS No. 209518-16-1. Molecular formula: C16H25NNa2O6S2. Mole weight: 437.48.
Magainin II TFA salt
Magainin II TFA salt.
Magainin I TFA
Magainin I TFA.
Magnesium Fumarate Tetrahydrate
Magnesium Fumarate Tetrahydrate.
Magnesium Orotate
Magnesium Orotate. CAS No. 34717-03-8.
Magnoflorine chloride
Magnoflorine chloride is an aporphine alkaloid found in flowers of Magnolia liliiflora Desr. It exhibits antioxidant, α-tyrosinase inhibitory and anti-inflammationary activities. Uses: Anti-inflammatory. Alternative Names: Magnoflorine, chloride; (6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium chloride; Corytuberine methochloride; Escholine chloride; Thalictrine chloride. Grades: >98%. CAS No. 6681-18-1. Molecular formula: C20H24NO4Cl. Mole weight: 377.87.
Magnolianin
Magnolianin is isolated from the bark of Magnolia obovata. Alternative Names: 1,2-Benzenediol, 5-[(2R,3R)-2,3-dihydro-3-[[(2'-hydroxy-5,5'-di-2-propen-1-yl[1,1'-biphenyl]-2-yl)oxy]methyl]-7-(2-propen-1-yl)-5-[4-(2-propen-1-yl)phenoxy]-1,4-benzodioxin-2-yl]-3-[4-(2-propen-1-yl)phenoxy]-, rel-. Grades: > 95%. CAS No. 147663-91-0. Molecular formula: C54H50O8. Mole weight: 827.00.
Magnoloside A
Magnoloside A isolated from the bark of Magnolia obovata. It is used for neurosis and gastrointestinal complaints as a japanese traditional medicine. Uses: Antistress. Alternative Names: 2-(3,4-Dihydroxyphenyl)ethyl 2-O-(6-deoxy-α-L-mannopyranosyl)-3-O -[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-allopyranoside. Grades: 0.96. CAS No. 113557-95-2. Molecular formula: C29H36O15. Mole weight: 624.6.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a non-cleavable ADC linker containing the Maleimide group, 2-unit PEG, and NHS ester. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]-1H-pyrrole-2,5-dione; 2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoate. Grades: ≥98%. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31.
Malvidin-3-O-arabinoside chloride
Malvidin-3-O-arabinoside chloride is found in the fruits of Vaccinium myrtillus, it shows antioxidant activity.It has potential preventive effect in colorectal diseases. Alternative Names: Malvidin 3-arabinoside. Grades: > 95%. CAS No. 28500-04-1. Molecular formula: C22H23ClO11. Mole weight: 498.87.
(+/-)-Mandelic Acid-[2,3,4,5,6-d5]
(+/-)-Mandelic Acid-[2,3,4,5,6-d5] is the labelled analogue of DL-Mandelic acid, which is an impurity of Pregabalin. Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. Alternative Names: α-Hydroxy-benzene-d5-acetic Acid. Grades: 98 atom % D. CAS No. 70838-71-0. Molecular formula: C8H3D5O3. Mole weight: 157.18.
Manidipine dihydrochloride
Manidipine is a calcium channel blocker with IC50 of 2.6 nM. It has been used in clinical treatment of hypertension. Uses: Antihypertensive agents. Alternative Names: CV-4093; CV 4093; CV4093. Grades: >98%. CAS No. 89226-75-5. Molecular formula: C35H38N4O6ยท2HCl. Mole weight: 683.62.
Manzamine A
Manzamine A is an alkaloid in the class of β-carboline isolated from the marine sponges. It acts as an inhibitor of glycogen synthase kinase 3β (GSK3β). It exhibits inhibitory effects against growth of the rodent malaria parasite Plasmodium berghei in vivo. Alternative Names: Manzamine A;104196-68-1;CHEMBL403233;Keramamine A;CHEBI:66667;(4aR,7S,7aR,13Z,14aR,15aR,18Z)-5-(9H-beta-carbolin-1-yl)-4,4a,9,10,11,12,14a,15-octahydro-3H-7,2-oct[3]enoazocino[1',2':1,5]pyrrolo[2,3-i]isoquinolin-7(1H,7aH)-ol;MANZAMINE;CHEMBL326531;SCHEMBL14377624;DTXSID001098329;BDBM50232478;AKOS040748872;HY-117025;CS-0063523;Q27135285;(1R,2R,4R,5Z,12R,13S,16Z)-25-(9H-pyrido[3,4-b]indol-1-yl)-11,22-diazapentacyclo[11.11.2.12,22.02,12.04,11]heptacosa-5,16,25-trien-13-ol;(1R,4S,9Z,13S,13aR,20aR,21aR)-2,3,5,6,7,8,11,12,15,16,17,18,20a,21-Tetradecahydro-24-(9H-pyrido[3,4-b]indol-1-yl)-1,13-etheno-4,21a-methano-1H-azocino[1a(2),2a(2):1,5]pyrrolo[3,2-e]azacyclopentadecin-13(13aH)-ol. Grades: ≥98%. CAS No. 104196-68-1. Molecular formula: C36H44N4O. Mole weight: 548.76.
MAOS
MAOS is a modified Trinder's reagent used in hydrogen peroxide determination. Alternative Names: 3-[(3,5-Dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt; Sodium 3-[(3,5-dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonate; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline Sodium Salt. Grades: ≥95%. CAS No. 82692-97-5. Molecular formula: C13H20NNaO4S. Mole weight: 309.36.