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Celiprolol Impurity B
N,N'-Bis[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea is an impurity of Celiprolol which is a cardioselective β1-adrenergic blocker. Alternative Names: N 113; Celiprolol Aniline Carboxy Dimer. Grades: > 95%. CAS No. 125579-40-0. Molecular formula: C31H46N4O7. Mole weight: 586.73.
Cenicriviroc
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Uses: Ccr2 receptor antagonists; ccr5 receptor antagonists. Alternative Names: (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide; TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; Cenicriviroc. Grades: ≥98%. CAS No. 497223-25-3. Molecular formula: C41H52N4O4S. Mole weight: 696.95.
Cenicriviroc mesylate
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Alternative Names: TAK-652 mesylate; TAK 652 mesylate; TBR-652 mesylate; TBR 652 mesylate. Grades: 99.04%. CAS No. 497223-28-6. Molecular formula: C42H56N4O7S2. Mole weight: 793.051.
Cephalocyclidin A
Cephalocyclidin A is isolated from the fruits of Cephalotaxus harringtonia var. nana. Alternative Names: (2S,8R,9R,10R,11S,12S)-16,18-Dioxa-4-azahexacyclo[11.7.0.02,9.04,8.08,12.015,19]icosa-1(13),14,19-triene-2,10,11-triol. Grades: 98%. CAS No. 421583-14-4. Molecular formula: C17H19NO5. Mole weight: 317.3.
Cerdulatinib HCl
Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Alternative Names: Cerdulatinib hydrochloride; PRT2070 hydrochloride; 4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide hydrochloride. Grades: >98%. CAS No. 1369761-01-2. Molecular formula: C20H28ClN7O3S. Mole weight: 482.
Ceritinib
An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Alternative Names: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. Grades: ≥98%. CAS No. 1032900-25-6. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14.
Cetirizine Glycerol Ester Impurity
An impurity of cetirizine, an antihistamine used to relieve allergy symptoms. Alternative Names: Cetirizine Glycerol Ester; Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, 2,3-dihydroxypropyl ester. Grades: > 95%. CAS No. 1243652-36-9. Molecular formula: C24H31ClN2O5. Mole weight: 462.98.
Cetirizine Impurity C dihydrochloride
Cetirizine Impurity C dihydrochloride. CAS No. 2702511-37-1.
Cetirizine N-Oxide Sodium Salt
An impurity of Cetirizine, which is an antihistamine used to relieve allergy symptoms. Grades: 95%. Molecular formula: C21H24NaClN2O4. Mole weight: 426.87.
Cetyl tranexamate hydrochloride
Cetyl tranexamate hydrochloride. CAS No. 913541-96-5.
CF-101
CF101 is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. CF101 has been shown to downregulate PKB/Akt and NF-κB protein expression level. CF101 potentiates the cytotoxic effect of 5-FU, thus preventing drug resistance. The myeloprotective effect of CF101 suggests its development as an add-on treatment to 5-FU. Alternative Names: CF101; CF-101; CF 101; ALB-7208; ALB 7208; ALB7208; IB MECA; Piclidenoson. CAS No. 152918-18-8. Molecular formula: C18H19IN6O4. Mole weight: 510.28.
CFDA-SE
CFDA-SE is an amine reactive dye for labeling cells, which is composed of a fluorescein molecule containing two acetate moieties and a succinimidyl ester (SE) functional group. It emits fluorescence when the acetate groups are cleaved by cellular esterases leaving CFSE. Alternative Names: 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester; 3',6'-bis(acetyloxy)-3-oxo-2,5-dioxo-1-pyrrolidinyl ester-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid. Grades: ≥90%. CAS No. 150347-59-4. Molecular formula: C29H19NO11. Mole weight: 557.5.
CGI1746
CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Alternative Names: CGI1746; CGI-1746; CGI 1746. 4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Grades: 98%. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69.
CGM097
CGM097 is an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, p53/HDM2 interaction inhibitor CGM097 inhibits the binding of the HDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis. HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Alternative Names: CGM097; CGM-097; CGM 097; NVPCGM097; NVPCGM 097; NVPCGM-097; NVP CGM097; NVP CGM 097; NVP CGM-097. CAS No. 1313363-54-0. Molecular formula: C38H47ClN4O4. Mole weight: 659.27.
CGP 35348
CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Alternative Names: CGP35348; CGP-35348; (3-Aminopropyl)(diethoxymethyl)phosphinic acid. Grades: 95% by NMR. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22.
CGP 52432
CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM. Alternative Names: Cgp 52432; Cgp52432; Cgp52432; 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid. Grades: >98 %. CAS No. 139667-74-6. Molecular formula: C15H24Cl2NO4P. Mole weight: 384.24.
CGS 15943
CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Alternative Names: CGS 15943; CGS15943; CGS-15943; 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine. Grades: ≥99% by HPLC. CAS No. 104615-18-1. Molecular formula: C13H8ClN5O. Mole weight: 285.69.
CH5424802 Hydrochloride
CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Alternative Names: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. Grades: >98%. CAS No. 1256589-74-8. Molecular formula: C30H35ClN4O2. Mole weight: 519.08.
Chaetochromin A
Chaetochromin A. Alternative Names: CHAETOCHROMIN A; CHAETOCHROMIN B; CHAETOCHROMIN D; CHAETOCHROMIN, STEREOISOMER; (9,9'-bi-4h-naphtho(2,3-b)pyran)-4,4'-dione,2,2',3,3'-tetrahydro-5,5',6,6',8,8; 3,3'-tetramethyl-'-hexahydroxy-2'; bis(naphthodihydropyran-4-one); chaetochromin. CAS No. 75514-37-3. Molecular formula: C30H26O10. Mole weight: 546.52.
Chalepensin
Chalepensin is a furanocoumarin found in several medicinal Rutaceae plants. Chalepensin acts as a cytochrome P450 (P450, CYP) inhibitor that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin also exhibits an antimicrobial effect against Streptococcus mutans. Alternative Names: Xylotenin; 3-(alpha,alpha-Dimethylallyl)psoralen; 6-(2-methylbut-3-en-2-yl)-7h-furo[3,2-g]chromen-7-one. Grades: 98.0%. CAS No. 13164-03-9. Molecular formula: C16H14O3. Mole weight: 254.285.
Chamaechromone
Chamaechromone is isolated from the roots of Stellera chamaeja sme. Chamaechromone can undergo extensive phase I and phase II metabolism in rat. Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2. Alternative Names: 3-[1,1-bis(4-hydroxyphenyl)-3-oxo-3-(2,4,6-trihydroxyphenyl)propan-2-yl]-5,7-dihydroxychromen-4-one. Grades: 98.0%. CAS No. 93413-00-4. Molecular formula: C30H22O10. Mole weight: 542.5.
Chamigrenal
Chamigrenal, a pharmacological treatment of anxiety disorders, intricately works towards ameliorating the perturbed functioning of the GABA receptors that ensue due to the hyperactivity of the brain. The convoluted mechanism of action mediates a stupor gently and minimizes the manifestation of anxiety symptoms. Additionally, it occasionally serves as an adjuvant in the management of insomnia. Alternative Names: Spiro[5.5]undec-2-ene-3-carboxaldehyde, 7,7-dimethyl-11-methylene-, (-)-. Grades: >98%. CAS No. 19912-84-6. Molecular formula: C15 H22 O. Mole weight: 218.33.
chavicol-4-o-b-D-glucopyranoside
chavicol-4-o-b-D-glucopyranoside. CAS No. 64703-98-6. Molecular formula: C15H20O6. Mole weight: 296.31.
Chebulic acid
Chebulic acid is a phenol isolated from Terminalia chebula with potent anti-oxidant activity. Alternative Names: (2S)-2-[(3S)-3,4-Dihydro-3α-carboxy-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4β-yl]butanedioic acid;Butanedioic acid,[(3S,4S)-3-carboxy-3,4-dihydro-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4-yl]-,(2S)-;Chebulic acid;Split acid;CHEBULIC ACID(SH);(2S)-[(3S,4S)-3-Carboxy-3,4-dihydro-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4-yl]butanedioic acid. Grades: 98%. CAS No. 23725-05-5. Molecular formula: C14H12O11. Mole weight: 356.2.
Chelerythrine
Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor. It is also the major active natural product found in the plant Zanthoxylum clava-herculis, exhibiting anti-bacterial activity against Staphylococcus aureus. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy. Uses: Antibacterial agent. Alternative Names: Toddalin; cheleritrine; broussonpapyrine; Toddaline; [1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-; NSC646662; 1,2-Dimethoxy-N-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride. Grades: 98%. CAS No. 34316-15-9. Molecular formula: C21H18NO4+. Mole weight: 348.37.
(-)-Chelidonine
(-)-Chelidonine is an alkaloid isolated from Glaucium squamigerum. Alternative Names: (-)-ChelidonineChelidonine, (-)-88200-01-5; UNII-S56Z5L310; WS56Z5L310W. Grades: 97.5%. CAS No. 88200-01-5. Molecular formula: C20H19NO5. Mole weight: 353.374.
Chilenine
Chilenine is an alkaloid isolated from the leaves of Hydrastis canadensis L. Alternative Names: Xylolin. Grades: 96.5%. CAS No. 71700-15-7. Molecular formula: C20H17NO7. Mole weight: 383.356.
Chimmitecan
Chimmitecan is a potent topoisomerase I inhibitor. Chimmitecan is also an active metabolite of simmitecan. Chimmitecan displays outstanding activity in vitro and in vivo. The substitution at the 9-position benefits chimmitecan a salient anti-MDR activity, stability in human serum albumin, improved solubility, and oral availability, which might favorably promise its therapeutic potential in clinical settings. Alternative Names: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-(2-propen-1-yl)-, (4S)-; (4S)-4-Ethyl-4,9-dihydroxy-10-(2-propen-1-yl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-(2-propenyl)-, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-(2-propenyl)-, (S)-; (S)-9-Allyl-10-Hydroxycamptothecin; (S)-10-allyl-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. Grades: ≥95%. CAS No. 185425-25-6. Molecular formula: C23H20N2O5. Mole weight: 404.42.
CHIR-090
CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Alternative Names: CHIR-090; CHIR 090; CHIR090. N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide. Grades: 98%. CAS No. 728865-23-4. Molecular formula: C24H27N3O5. Mole weight: 437.49.
Chlomethoxyfen-[d3]
Chlomethoxyfen-[d3] is a deuterium labelled Chlomethoxyfen, a larely obsolete herbicide. Alternative Names: Chlomethoxyfen-d3. Molecular formula: C13H6D3Cl2NO4. Mole weight: 317.14.
Chlorambucil
Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. Alternative Names: gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid. Grades: >98%. CAS No. 305-03-3. Molecular formula: C14H19Cl2NO2. Mole weight: 304.21.
Chlorhexidine Diacetate Impurity C
An impurity standard for Chlorhexidine. Alternative Names: N1,N14-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamide. Grades: > 95%. CAS No. 62247-48-7. Molecular formula: C22H28Cl2N8O2. Mole weight: 507.43.
Chlorhexidine EP Impurity E
Chlorhexidine EP Impurity E is one of chlorhexidine impurities. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Alternative Names: N-(4-chlorophenyl)guanidine; N-(4-Chloro-phenyl)-guanidine; p-Chlorphenylguanidine; 1-(4-Chlorophenyl)guanidine; 1N-amino(immino)methyl-4-chloroaniline. Grades: > 98%. CAS No. 45964-97-4. Molecular formula: C7H8ClN3. Mole weight: 169.61.
Chlorhexidine EP Impurity L
Chlorhexidine EP Impurity L is one of chlorhexidine impurities. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Alternative Names: Chlorhexidine oxazinone analog; (5R,6S)-2-[(4-Chlorophenyl)amino]-5-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-1,3-oxazin-4-one. Molecular formula: C13H15ClN2O6. Mole weight: 330.72.
Chlorhexidine EP Impurity O DiHCl
Chlorhexidine EP Impurity O DiHCl is one of chlorhexidine impurities. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Alternative Names: N1-[6-[[N-[N-(2-chlorophenyl)carbamimidoyl]carbamimidoyl]amino]hexyl]-N3-(4-chlorophenyl)imidodicarbonimidic diamide, hydrochloride (1:2). Molecular formula: C22H30Cl2N10.2HCl. Mole weight: 578.37.
Chlorhexidine EP Impurity P
An impurity of Chlorhexidine, an antiseptic and disinfectant commonly used as the diacetate or digluconate salt. Chlorhexidine disrupts microbial cell membranes and coagulates cytoplasmic proteins. Alternative Names: p-Chloroaniline; 4-Chlorobenzenamine. CAS No. 106-47-8. Molecular formula: C6H6ClN. Mole weight: 127.57.
Chlorphenamine maleate EP Impurity C
Chlorphenamine maleate EP Impurity C. CAS No. 20619-12-9.
Chlorphenamine maleate EP Impurity D
Chlorphenamine maleate EP Impurity D. CAS No. 65676-21-3.
Chlortalidone EP Impurity F
Dimer Conjugate of Chlorthalidone, a diuretic and antihypertensive agent. Alternative Names: Chlorthalidone Dimer; bis[2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulphonyl]amine; 2-Chloro-N-(2-chloro-5-(1-hydroxy-3-oxoisoindolin-1-yl)phenylsulfonyl)-5-(1-hydroxy-3-oxoisoindolin-1-yl)benzenesulfonamide. Grades: > 95%. CAS No. 1796929-84-4. Molecular formula: C28H19Cl2N3O8S2. Mole weight: 660.51.
Cholecalciferol EP Impurity D
A degradation product of Vitamin D3. It has been shown to stimulate intestinal Ca transport and bone Ca mobilization in anephric rats. Alternative Names: iso-Tachysterol 3; Isotachysterol 3; (3β,6E)-9,10-Secocholesta-5(10),6,8(14)-trien-3-ol; (E)-9,10-Secocholesta-5(10),6,8(14)-trien-3β-ol. Grades: 98%. CAS No. 22350-43-2. Molecular formula: C27H44O. Mole weight: 384.64.
Choline bis(trifluoromethylsulfonyl)imde
Choline bis(trifluoromethylsulfonyl)imde. Alternative Names: 2-Hydroxy-N,N,N-trimethylethan-1-aminium bis((trifluoromethyl)sulfonyl)amide. CAS No. 827027-25-8. Molecular formula: C7H14F6N2O5S2. Mole weight: 384.32.
Choline Fenofibrate
Choline fenofibrate is a hydrophilic formulation of fenofibric acid that acts primarily by activating peroxisome proliferator-activated receptor alpha (PPARα). This nuclear receptor modulates the transcription of genes involved in lipid metabolism. Once activated, PPARα increases the expression of lipoprotein lipase (LPL), which hydrolyzes triglycerides in lipoproteins, thereby reducing plasma triglyceride levels. It also decreases the production of apolipoprotein C-III (ApoC-III), an inhibitor of LPL, further promoting triglyceride breakdown. Additionally, choline fenofibrate stimulates the synthesis of high-density lipoprotein cholesterol (HDL-C) by upregulating the expression of apolipoprotein A-I (ApoA-I) and apolipoprotein A-II (ApoA-II). This multifaceted mechanism helps in managing mixed dyslipidemia by lowering triglycerides and increasing HDL-C levels. Alternative Names: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate (1:1); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid (1:1); ABT 335; FNFC; Trilipix. Grades: >98%. CAS No. 856676-23-8. Molecular formula: C22H28ClNO5. Mole weight: 421.91.
Wilsonine is a natural alkaloid found in the herbs of Cephalotaxus sinensis. Alternative Names: C-Homoerythrinan, 1,2-didehydro-6,7-epoxy-3,15,16-trimethoxy-, (3alpha ,6xi)-. Grades: >98%. CAS No. 39024-12-9. Molecular formula: C20H25NO4. Mole weight: 343.4.
Chondroitinase AC
Chondroitinase AC. Alternative Names: Chondroitin AC lyase; Chondroitin AC eliminase. CAS No. 9047-57-8.
Chrysocauloflavone I
Chrysocauloflavone I, an unfrequent biflavonoid, is purified from Selaginella doederleinii. Grades: 98.0%. CAS No. 899789-51-6. Molecular formula: C30H20O10. Mole weight: 540.48.
Chrysoeriol
Chrysoeriol is a natural compound isolated from the herbs of Medicago sativa. Chrysoeriol can potently inhibit the induction of nitric oxide synthase by blocking activator protein 1 (AP-1) activation and its anti-inflammatory effects. Chrysoeriol can induce nod genes in rhizobium meliloti. Chrysoeriol can inhibit the downstream signal transduction pathways of platelet-derived growth factor (PDGF)-Rbeta, including ERK1/2, p38, and Akt phosphorylation, which suggests that chrysoeriol may be used for the prevention and treatment of vascular diseases during restenosis after coronary angioplasty. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether; Scoparol; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-. Grades: 98.0%. CAS No. 491-71-4. Molecular formula: C16H12O6. Mole weight: 300.27.
Chrysosplenetin
Chrysosplenetin is a flavonoid isolated from the herbs of Laggera pterodonta, which is a metabolic inhibitor of artemisinin. Uses: Anti-enterovirus 71. Alternative Names: Chrysosplenetin B; 3,6,7,3'-Tetramethylquercetagetin; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one; EMD-20940; 4H-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-. Grades: 99%. CAS No. 603-56-5. Molecular formula: C19H18O8. Mole weight: 374.4.
CHRYSOSPLENOLD
Chrysosplenol D isolated from the herbs of Artemisia annua L. Uses: Antibiotics and antimalarials. Alternative Names: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one. Grades: 98.5%. CAS No. 14965-20-9. Molecular formula: C18H16O8. Mole weight: 360.3.
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Rejuvenail, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. Alternative Names: Ciclopirox. Grades: >98%. CAS No. 29342-05-0. Molecular formula: C12H17NO2. Mole weight: 207.27.
CID-25014542
CID-25014542 is a Raf kinase inhibitor. Alternative Names: CID-25014542; CID25014542; CID 25014542. 5-Chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one; (3Z)-5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1H-indol-2-one. CAS No. 220904-99-4. Molecular formula: C15H8Br2ClNO2. Mole weight: 429.492.
Cilofexor
Cilofexor is a farnesoid X receptor (FXR) agonist. Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). Alternative Names: 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 1418274-28-8. Molecular formula: C28H22Cl3N3O5. Mole weight: 586.9.
Cimicoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2. It is used in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs. Alternative Names: UR-8880; UR 8880; UR8880. Grades: >98%. CAS No. 265114-23-6. Molecular formula: C16H13ClFN3O3S. Mole weight: 381.8.
Cinacalcet Dihydro Impurity 1 HCl
Cinacalcet Dihydro Impurity 1 HCl is an impurity in commercial preparations of Cinacalcet. Alternative Names: N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride. Grades: > 95%. CAS No. 1020414-33-8. Molecular formula: C22H25ClF3N. Mole weight: 395.89.
Cinacalcet Impurity 18
An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Alternative Names: (R)-1-(5,6-Dihydronaphthalen-1-yl)ethan-1-amine. Grades: > 95%. CAS No. 1020414-30-5. Molecular formula: C12H15N. Mole weight: 173.26.
Cinacalcet Impurity 7
An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Alternative Names: Methanesulfonic acid 3-(3-trifluoromethylphenyl)propyl ester. Grades: > 95%. CAS No. 21172-43-0. Molecular formula: C11H13F3O3S. Mole weight: 282.28.
Cinacalcet Impurity B (HCl salt form)
Cinacalcet Impurity B (HCl salt form) is an impurity of Cinacalcet, a medication used to treat secondary hyperparathyroidism in patients with chronic kidney disease and parathyroid carcinoma. Alternative Names: (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE; (R)-N-BENZYL 1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE; (R)-N-[1-(1-NAPHTHYL)ETHYL]BENZYLAMINE HYDROCHLORIDE; (R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMI&; N-benzyl-1-(1-naphthyl)ethylamine hydrochloride. Grades: 95%. CAS No. 163831-65-0. Molecular formula: C19H20ClN. Mole weight: 297.82.
Cinacalcet Impurity D
N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet is an impurity of Cinacalcet Hydrochloride. Cinacalcet is used in clinical trial in secondary hyperparathyroidism. Alternative Names: N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet; (αR)-α-Methyl-N,N-bis[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine. Grades: > 95%. CAS No. 1271930-15-4. Molecular formula: C32H31F6N. Mole weight: 543.59.
Cinacalcet USP Related Compound C
Cinacalcet USP Related Compound C is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Alternative Names: Cinacalcet Para-Trifluoromethyl Analog; (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine Hydrochloride; (alphaR)-alpha-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethan. Grades: 95%. CAS No. 1428118-39-1. Molecular formula: C22H23ClF3N. Mole weight: 393.88.
Cinchonain IIa
Cinchonain Iia is a natural compound isolated from the barks of Kandelia candel. Cinchonain IIa has antioxidant activity, high radical scavenging activity and reducing power. Alternative Names: (2R,3R,4S,10R)-2,10-bis(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-3,5-dihydroxy-3,4,9,10-tetrahydro-2H-pyrano[2,3-h]chromen-8-one. Grades: 97.5%. CAS No. 85081-23-8. Molecular formula: C39H32O15. Mole weight: 740.66.
Cinchonain IIb
Cinchonain Iib is purified from the barks of Kandelia candel (L.) DRUCE. Cinchonain IIb shows high radical scavenging activity and reducing power. Alternative Names: (2R,3R,4S,10S)-2,10-bis(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-3,5-dihydroxy-3,4,9,10-tetrahydro-2H-pyrano[2,3-h]chromen-8-one. Grades: 90.0%. CAS No. 85022-68-0. Molecular formula: C39H32O15. Mole weight: 740.66.
Cinitapride
Cinitapride is a gastroprokinetic agent and antiemetic agent of the benzamide class. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors. Alternative Names: Benzamide, 4-amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitro-; 4-Amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitrobenzamide. Grades: ≥95%. CAS No. 66564-14-5. Molecular formula: C21H30N4O4. Mole weight: 402.49.
Cinnamtannin B1
Cinnamtannin B1, a phenolic constituent sourced from the bark of Cinnamomum cassia, displays credible potential as a therapeutic agent in tackling various ailments such as diabetes, obesity, and cancer. Its multifaceted medicinal properties ranging from antioxidant, anti-inflammatory, to antiproliferative activities render it a hopeful candidate for novel drug advancement. Alternative Names: Cinnamtannin B1; cinnamtannin B-1; 88082-60-4; CinnamtanninB-1; CHEBI:69304. Grades: > 95%. CAS No. 88082-60-4. Molecular formula: C45H36O18. Mole weight: 864.76.
Cinnzeylanol
Cinnzeylanol is isolated from the barks of Cinnamomum cassia. Alternative Names: 3-Deoxyryanodol. Grades: 97%. CAS No. 62394-04-1. Molecular formula: C20H32O7. Mole weight: 384.5.
Cinoxacin-[d5]
Cinoxacin-[d5] is a labelled Cinoxacin. Cinoxacin, a quinolone carboxylic acid derivative that structurally resembles ciprofloxacin, was an older synthetic antimicrobial to treat urinary tract infections. Alternative Names: 1-Ethyl-D5-4-oxo-1,4-dihydro-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid. Grades: 95% by HPLC; 98% atom D. Molecular formula: C12H5D5N2O5. Mole weight: 267.25.
Ciprofloxacin-[d8]
Ciprofloxacin-[d8] is the labelled analogue of Ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections. Alternative Names: Ciprofloxacin D8; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-d8-1-yl-1,4-dihydro-quinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid; Ciflafin-d8; Ciprine-d8; Cipro IV-d8; Ciprobay 100-d8; Ciprofloxacillin-d8. Grades: 95% by HPLC; 98% atom D. CAS No. 1130050-35-9. Molecular formula: C17H10D8FN3O3. Mole weight: 339.39.
Ciprofloxacin EP Impurity C
An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Alternative Names: Enrofloxacin EP impurity G; Ciprofloxacin Ethylenediamine Analog (USP); Desethylene Ciprofloxacin, Hydrochloride; M1-Ciprofloxacin; 7-[(2-Aminoethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid. Grades: 95%. CAS No. 528851-31-2. Molecular formula: C15H17ClFN3O3. Mole weight: 341.76.
Ciprofloxacin EP Impurity E
An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Alternative Names: Decarboxy Ciprofloxacin; Decarboxyciprofloxacin; 1-Cyclopropyl-6-fluoro-7-(1-piperazinyl)-4(1H)-quinolinone. Grades: > 95%. CAS No. 105394-83-0. Molecular formula: C16H18FN3O. Mole weight: 287.34.