BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Camalexin | Camalexin is an indole phytoalexin Camelina sativa and Arabidopsis (Cruciferae), exhibiting antibacterial, antifungal, antiproliferative and anticancer activities. Uses: Anti-infective agents. Alternative Names: 3-(1,3-thiazol-2-yl)-1H-indole; 3-(thiazol-2-yl)indole. Grades: 98%. CAS No. 135531-86-1. Molecular formula: C11H8N2S. Mole weight: 200.26. |  |
| Canagliflozin hemihydrate | Canagliflozin hemihydrate is a highly potent and selective inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. It is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes. Uses: The potential treatment of type 2 diabetes. Alternative Names: (3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hemihydrate; JNJ 28431754 hemihydrate; TA 7284 hemihydrate; JNJ-24831754-ZAE hemihydrate; JNJ-28431754-AAA hemihydrate; (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol hydrate (2:1); Cagliflozin hydrate; Invokana hemihydrate; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate. Grades: >98%. CAS No. 928672-86-0. Molecular formula: C24H25FO5S.1/2H2O. Mole weight: 453.53. | |
| Candesartan-[d4] | The isotope labelled form of Candesartan which is an angiotensin II type-1 receptor antagonist and could be used against hypertension and congestive heart failure. Alternative Names: 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid; CV-11974-d4; Candesartan M1-d4; 3-[[2'-(1H-Tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic Acid. Grades: ≥95% by HPLC; ≥98% atom D. CAS No. 1346604-70-3. Molecular formula: C24H16D4N6O3. Mole weight: 444.48. | |
| Cangrelor tetrasodium | Cangrelor tetrasodium is an ATP analogue and acts as a reversible antagonist of P2Y12 receptor. Pretreatment with cangrelor significantly reduces blood clotting induced by ADP in a mouse model of pulmonary thromboembolism. Alternative Names: Cangrelor Tetrasodium; AR-C69931MX; AR C69931MX; ARC69931MX; N6-(2-Methylthioethyl)-2-(3,3,3-trifluoropropylthio)-betagamma-dichloromethylene-ATP tetrasodium salt. CAS No. 163706-36-3. Molecular formula: C17H21Cl2F3N5Na4O12P3S2. Mole weight: 864.274. | |
| Capecitabine impurity D | A Capecitabine analog which shows antitumor activity. Alternative Names: 5'-Deoxy-5-fluoro-N4-[(2-methylbutoxy)carbonyl]cytidine; 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine; Capecitabine EP Impurity D; 2-Methylbutyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 5'-Deoxy-5-fluoro-N4-(2-methyl-1-butyloxycarbonyl)cytidine. Grades: ≥95%. CAS No. 910129-15-6. Molecular formula: C15H22FN3O6. Mole weight: 359.35. | |
| Capecitabine impurity F | It is an impurity of Capecitabine and is used as an antitumor agent. Alternative Names: 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine; [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-carbamic Acid 3-Methylbutyl Ester; 5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine; Isopentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 5'-Deoxy-5-fluoro-N4-(3-methyl-1-butyloxycarbonyl)cytidine; Capecitabine impurity E. Grades: ≥95%. CAS No. 162204-30-0. Molecular formula: C15H22FN3O6. Mole weight: 359.35. | |
| Captopril-cysteine Disulfide | Captopril-cysteine Disulfide is an impurity of Captopril, an orally active angiotensin-converting enzyme (ACE) inhibitor. Alternative Names: Captopril-cysteine; 1-[(2S)-3-[[(2R)-2-Amino-2-carboxyethyl]dithio]-2-methyl-1-oxopropyl]-L-proline. CAS No. 75479-46-8. Molecular formula: C12H20N2O5S2. Mole weight: 336.43. | |
| Captopril disulfide | A metabolite of Captopril, an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Alternative Names: 1,1'-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS; SQ 14551; Captopril Imp. A (BP); Captopril EP Impurity A. Grades: > 95%. CAS No. 64806-05-9. Molecular formula: C18H28N2O6S2. Mole weight: 432.56. | |
| Carbadox-[d3] | Carbadox-[d3], is the labelled analogue of Carbadox. Carbadox is a veterinary drug that combats infection in swine, particularly swine dysentery. Alternative Names: (Quinoxalin-2-yl methylene)hydrazinecarboxylic acid methyl-D3 ester 1,4-dioxide; Carbadox-d3; Carbadox-D3. CAS No. 1185240-06-5. Molecular formula: C11H7D3N4O4. Mole weight: 265.24. | |
| Carbamazepine EP Impurity G | Carbamazepine EP Impurity G is an impurity of Carbamazepine, a medication used in the treatment of epilepsy and neuropathic pain. Alternative Names: 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide; 5-bromobenzo[b][1]benzazepine-11-carboxamide. Grades: >95%. CAS No. 59690-97-0. Molecular formula: C15H11BrN2O. Mole weight: 315.17. | |
| Carbamic acid, N-[(1S)-1-methyl-4-oxo-4-(3,4,5-trifluorophenyl)butyl]-, 1,1-dimethylethyl ester | Carbamic acid, N-[(1S)-1-methyl-4-oxo-4-(3,4,5-trifluorophenyl)butyl]-, 1,1-dimethylethyl ester. CAS No. 2488869-97-0. | |
| Carbamodithioic acid, methyl ester | Carbamodithioic acid, methyl ester. Alternative Names: (methylsulfanyl)carbothioamide; S-Methyl Dithiocarbamate; Carbamic acid, dithio-, methyl ester. Grades: 98%. CAS No. 16696-83-6. Molecular formula: C2H5NS2. Mole weight: 107.20. | |
| carbazole-[d8] | Carbazole-[d8], an isotope-enhanced variation of the organic compound carbazole, exhibits immense utility as a precursor to an assortment of dyes and pharmaceuticals. Its potency extends to the synthesis of photovoltaic cells and OLEDs as well. Alternative Names: carbazole-d8; carbazole d8. Grades: 98% atom D. CAS No. 38537-24-5. Molecular formula: C12HD8N. Mole weight: 175.25. | |
| (Carbethoxymethyl)Triphenylphosphonium Bromide-[13C2] | (Carbethoxymethyl)Triphenylphosphonium Bromide-[13C2]. Alternative Names: [2-Ethoxy-2-oxo(13C2)ethyl](triphenyl)phosphanium bromide; (Carbethoxymethyl-1,2-13C2)triphenylphosphonium bromide. CAS No. 109376-35-4. Molecular formula: C20[13C]2H22BrO2P. Mole weight: 431.27. | |
| Carbidopa Related Compound A | Carbidopa Related Compound A is an impurity of Carbidopa. Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM. It inhibits the conversion of levodopa to dopamine. Alternative Names: 3-O-Methyl Carbidopa; 3-O-Methylcarbidopa; Carbidopa EP Impurity C; α-Hydrazino-4-hydroxy-3-methoxy-α-methylbenzenepropanoic Acid. Grades: ≥95%. CAS No. 85933-19-3. Molecular formula: C11H16N2O4. Mole weight: 240.26. | |
| (+/-)-Carbinoxamine Maleate-[N,N-dimethyl-d6] | (+/-)-Carbinoxamine Maleate-[N,N-dimethyl-d6], is the labelled analogue of Carbinoxamine Maleate. Carbinoxamine maleate is an impurity of Carbinoxamine, which is an analgesic and anti-inflammatory compound. Alternative Names: (2Z)-but-2-enedioic acid; {2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}bis(D3)methylamine; (+/-)-Carbinoxamine D6 Maleate (N,N-dimethyl-d6); (±)-2-[(4-Chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethylethylamine Maleate. Grades: 98% atom D. CAS No. 1216872-59-1. Molecular formula: C20H17D6ClN2O5. Mole weight: 412.9. | |
| Carboprost tromethamine | Carboprost tromethamine is the salt of Carboprost, an analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha). Carboprost activates prostaglandin F receptor, and causes smooth muscle contractions. Alternative Names: Hemabate; Carboprost Trometanol; 2-amino-2-(hydroxymethyl)propane-1,3-diol;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid. Grades: > 98%. CAS No. 58551-69-2. Molecular formula: C25H47NO8. Mole weight: 489.65. | |
| Carboxyatractyloside | Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier. Alternative Names: Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-; (2β,5β,8α,9β,10α,13α,15α)-15-Hydroxy-2-{[2-O-(3-methylbutanoyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy}kaur-16-ene-18,19-dioic acid; (2S,4aS,6aR,7S,9R,11aS,11bS)-7-hydroxy-2-(((2R,3R,4R,5R,6R)-6-(hydroxymethyl)-3-((3-methylbutanoyl)oxy)-4,5-bis(sulfooxy)tetrahydro-2H-pyran-2-yl)oxy)-11b-methyl-8-methylenedodecahydro-6a,9-methanocyclohepta[a]naphthalene-4,4(1H)-dicarboxylic acid; C 4992. Grades: >98%. CAS No. 77228-71-8. Molecular formula: C31H46O18S2. Mole weight: 770.81. | |
| Carboxy Citalopram | Carboxy Citalopram. CAS No. 440121-09-5. | |
| Carboxymethyl cellulose sodium | Carboxymethyl cellulose sodium is widely used in oral and topical pharmaceutical formulations, mainly because of its viscosity-increasing properties. Carboxymethyl cellulose sodium can also be used as a tablet binder, disintegrant and stabilizing emulsion. Uses: Used in drilling muds, detergents, resin emulsion paints, adhesives, printing inks, and textile sizes; also used as a protective colloid, a stabilizer for foods, and a pharmaceutical additive; used as a bulk laxative, emulsifier and thickener in cosmetics and pharmaceuticals, and stabilizer for reagents; formerly registered in the us for use as an insecticide for ornamentals and flowering plants. Alternative Names: Cellulose, carboxymethyl ether, sodium salt; CM Cellulose; Carmellose; Almelose; Glycolic acid cellulose ether; Carboxymethyl cellulose; Carboxymethyl cellulose ether; Carboxymethyl cellulose sodium salt; Carboxymethylated cellulose sodium salt; Carboxymethylcellulose; Carmacel P-(CC); Carmellose sodium; Cellugel; Cellulose carboxymethylate sodium salt; Cellulose glycolate; Cellulose Gum 9M8; Cell. CAS No. 9004-32-4. Molecular formula: [C6H7O2(OH)x(C2H2O3Na)y]n.… | |
| Cariprazine hydrochloride | The hydrochloride salt form of Cariprazine, which is a highly selective inhibitor of Dopamine D3 and D2 receptor so that it might be effective as an antipsychotic agent. It has also been found to have moderate selectivity to serotonin 5-HT(1A) receptors. Uses: Antipsychotic agents. Alternative Names: Cariprazine HCl; Vraylar; 3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea hydrochloride. Grades: > 98%. CAS No. 1083076-69-0. Molecular formula: C21H33Cl3N4O. Mole weight: 463.87. | |
| Cariprazine-[piperazine-d8] | Cariprazine-[piperazine-d8] is a labelled Cariprazine. Cariprazine is an atypical antipsychotic used for the treatment of schizophrenia and bipolar mania. Alternative Names: Cariprazine-d8; 3-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)ethyl)cyclohexyl)-1,1-dimethylurea; 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)(D8)piperazin-1-yl]ethyl}cyclohexyl]urea; N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethyl]cyclohexyl]-N,N-dimethylurea; Cariprazine D8. Grades: 95% by HPLC; 98% atom D. CAS No. 1308278-50-3. Molecular formula: C21H24D8Cl2N4O. Mole weight: 435.46. | |
| Carmustine | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Alternative Names: 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin. Grades: ≥98%. CAS No. 154-93-8. Molecular formula: C5H9Cl2N3O2. Mole weight: 214.05. | |
| Carnosol | Carnosol is a natural diterpenoid compound isolated from the herbs of Rosmarinus officinalis L. Carnosol exhibits anti-oxidative, anti-inflammatory and antiproliferative activities. Alternative Names: Picrosalvin; 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-(4aalpha,9alpha,10abeta))-. Grades: >98%. CAS No. 5957-80-2. Molecular formula: C20H26O4. Mole weight: 330.42. | |
| Carpalasionin | Carpalasionin is a natural diterpenoid compound found in several plants. Alternative Names: (12R)-21-Acetyloxy-13-deoxy-5β-hydroxyenmein; (5beta,12alpha)-21-(Acetyloxy)-13-deoxy-5-hydroxyenmein. Grades: >95%. CAS No. 83150-97-4. Molecular formula: C22H28O8. Mole weight: 420.45. | |
| Carpinontriol A | Carpinontriol A is an esteemed natural compound, aiding in studying the burden of conditions like rheumatoid arthritand multiple sclerosis. Grades: 97.0%. CAS No. 473451-72-8. Molecular formula: C19H20O6. Mole weight: 344.364. | |
| Carpinontriol B | Carpinontriol B is a natural compound isolated from the herbs of Carpinus turczaninowii. Alternative Names: Giffonin T. Grades: 98.0%. CAS No. 473451-73-9. Molecular formula: C19H20O6. Mole weight: 344.363. | |
| Carthamidin | Carthamidin. CAS No. 479-54-9. | |
| Caspofungin Impurity E | Caspofungin Impurity E is an impurity of Caspofungin, an antifungal agent in echinocandin class. Caspofungi is effective against infections with Aspergillus and Candida and functions via inhibiting β(1,3)-D-Glucan of the fungal cell wall. Molecular formula: C50H82N8O16. Mole weight: 1051.23. | |
| Cassiachromone | Cassiachromone is a natural chromone isolated from the leaves of Senna siamea. Alternative Names: 5-Acetonyl-7-hydroxy-2-methylchromone; 2-Methyl-5-acetonyl-7-hydroxychromone. Grades: >95%. CAS No. 28955-30-8. Molecular formula: C13H12O4. Mole weight: 232.2. | |
| (+)-Cassythicine | Cassythicine is an alkaloid isolated from Litsea glutinosa. Alternative Names: (+)-Cassythicine. Grades: 96.0%. CAS No. 5890-28-8. Molecular formula: C19H19NO4. Mole weight: 325.364. | |
| Catalponol | Catalponol isolated from the roots of Ekmanianthe longiflora. It can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells. Grades: > 95%. CAS No. 34168-56-4. Molecular formula: C15H18O2. Mole weight: 230.3. | |
| (±)-Catechin-[13C3] | (±)-Catechin-[13C3], is the labelled analogue of Catechin. Catechin is a flavan-3-ol, a type of natural phenol and antioxidant. Alternative Names: (+/-)-Catechin-2,3,4-13C3. Grades: 98% by CP; 99% atom 13C. CAS No. 1261254-33-4. Molecular formula: C12[13C]3H14O6. Mole weight: 293.25. | |
| Catechin 3-rhamnoside | Catechin 3-rhamnoside is a natural flavonoid found in the stems of Erythroxylum novogranatense, it exhibits the activity of antioxidant. Alternative Names: a-L-Mannopyranoside,2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyr an-3-yl6-deoxy-, (2R-trans)-; Catechin 3-O-a-L-rhamnopyranoside. Grades: >97%. CAS No. 103630-03-1. Molecular formula: C21H24O10. Mole weight: 436.4. | |
| Catechin pentaacetate | Catechin pentaacetate is isolated from the bark of Taxus yunnanensis. Alternative Names: (+)-Catechin-pentaacetate; (2R)-2α-(3,4-Diacetoxyphenyl)-3β,5,7-triacetoxy-3,4-dihydro-2H-1-benzopyran; (2R)-3,4-Dihydro-2α-(3,4-dihydroxyphenyl)-2H-1-benzopyran-3β,5,7-triol pentaacetate. Grades: > 95%. CAS No. 16198-01-9. Molecular formula: C25H24O11. Mole weight: 500.5. | |
| Catharanthine sulfate | Catharanthine is a natural compound isolated from Catharanthus roseus. It exhibits antitumor activity. Alternative Names: Catharanthine sulfate; 70674-90-7; Catharanthine (Sulfate); Catharanthine xSulfate; methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate; sulfuric acid; (+)-3,4-Didehydrocoronaridine (Sulfate); CHEMBL2435219; HY-N0252B; EX-A173; CATHARANTHINE; SULFURIC ACID; MFCD06410943; AKOS032946176; AC-34404; PD087203; CS-0009006. Grades: >98%. CAS No. 70674-90-7. Molecular formula: C21H26N2O6S. Mole weight: 434.5. | |
| Caulilexin A | Caulilexin A is a phytoalexin found in Brassica oleracea, which exhibits antifungal activity. Alternative Names: Caulilexine A; 2-(Methyldithio)-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2-(methyldithio)-. Grades: ≥95%. CAS No. 905914-67-2. Molecular formula: C10H9NOS2. Mole weight: 223.32. | |
| Caulophylline B | Caulophylline B is an alkaloid isolated from the roots of Caulophyllum robustum Maxim. Alternative Names: 1-(2-(Dimethylamino)ethyl)-4,5-dihydroxy-3,6-dimethoxy-9H-fluoren-9-one. Grades: 98.0%. CAS No. 1359978-55-4. Molecular formula: C19H21NO5. Mole weight: 343.379. | |
| Cavaol E | Cavaol E is a natural compound commonly found in plants with potential biomedical applications. Studies have shown that Cavaol E exhibits antioxidant and anti-inflammatory properties, making it a promising candidate for studying oxidative stress-related diseases such as cancer and cardiovascular disorders. CAS No. 1233044-20-6. Molecular formula: C25H36O9. Mole weight: 480.555. | |
| CAY10499 | Monoglyceride lipase (MGL) plays an important role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). CAY10499 is a potent and selective monoglyceride lipase (MGL) inhibitor exhibiting an IC50 of 90 nM for the recombinant enzyme. It is also a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 mM, respectively). Alternative Names: CAY-10499; CAY 10499; Magl-IN-5. Grades: ≥98%. CAS No. 359714-55-9. Molecular formula: C18H17N3O5. Mole weight: 355.34. | |
| CB-839 | CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. Upon oral administration, CB-839 selectively and irreversibly inhibits glutaminase, a mitochondrial enzyme that is essential for the conversion of the amino acid glutamine into glutamate. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). ( ). Alternative Names: CB-839; CB839; CB 839. Grades: 98%. CAS No. 1439399-58-2. Molecular formula: C26H24F3N7O3S. Mole weight: 571.57. | |
| CBL0137 | CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM. It also inhibits histone chaperone FACT (facilitates chromatin transcription) and MYC signal. Alternative Names: CBL0137; CBL-0137; CBL 0137; CBLC137; CBLC-137; CBLC 137; Curaxin 137; 1,1'-(9-(2-(Isopropylamino)ethyl)-9H-carbazole-3,6-diyl)diethanone; 1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone. CAS No. 1197996-80-7. Molecular formula: C21H24N2O2. Mole weight: 336.435. | |
| CBL0137 hydrochloride | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death. Alternative Names: CBLC137; CBL-0137; Curaxin 137. Grades: ≥98%. CAS No. 1197397-89-9. Molecular formula: C21H24N2O2·HCl. Mole weight: 372.9. | |
| CC122 | CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial. Uses: Cc122 has antitumor and immunomodulatory activity. it is used for the treatment of chronic lymphocytic leukemia. Alternative Names: 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione;CC-122; CC122; CC 122. Grades: >98 %. CAS No. 1015474-32-4. Molecular formula: C14H14N4O3. Mole weight: 286.29. | |
| CC-17368 | CC-17368 is a hydroxyisoindole derivative and metabolite of pomalidomide that has potential activity in anticancer study like multiple myeloma. Alternative Names: CC 17368; CC17368; Pomalidomide metabolite M17; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-. Grades: 98%. CAS No. 1547162-41-3. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-223 | CC-223, a mTOR kinase inhibitor, has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. It is still under Phase I/II clinical trial by Celgene Corporation. IC50: 16 nM. Uses: Cc-223 is a mtor kinase inhibitor that has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. Alternative Names: CC-223; CC 223; CC223; UNII-I8RA3543SY; I8RA3543SY; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyraz. Grades: 98%. CAS No. 1228013-30-6. Molecular formula: C21H27N5O3. Mole weight: 397.47. | |
| CC-885 | CC-885 is a cereblon (CRBN) modulator with an anti-tumour activity mediated through the cereblon-dependent ubiquitination and degradation of the translation termination factor GSPT1. CC-885 potently suppresses the proliferation of human acute myeloid leukaemia (AML) tumour cell lines. Uses: Antitumor agent. Alternative Names: CC 885; CC885; N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea. Grades: 99%. CAS No. 1010100-07-8. Molecular formula: C22H21ClN4O4. Mole weight: 440.88. | |
| CCG 50014 | CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM, exhibiting >20-fold selectivity over other RGS proteins. Alternative Names: CCG50014; CCG-50014; 4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione. Grades: >98%. CAS No. 883050-24-6. Molecular formula: C16H13FN2O2S. Mole weight: 316.35. | |
| CCP peptide TFA | CCP peptide TFA is a synthetic cyclic citrullinated peptide that can be used as the substrate for detecting anti-CCP antibodies serologically. Alternative Names: His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16). Grades: 95%. Molecular formula: C89H146N41F3O34S2. Mole weight: 2455.49. | |
| CDC25B-IN-1 | CDC25B-IN-1. CAS No. 2374831-10-2. | |
| CDDO Imidazolide | CDDO Imidozolide is a synthetic triterpenoid as a Nrf2 signaling activator with highly active in suppressing cellular proliferation of human leukemia and breast cancer cell. Uses: Nrf2 signaling activator. Alternative Names: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile. Grades: ≥98 %. CAS No. 443104-02-7. Molecular formula: C34H43N3O3. Mole weight: 541.72. | |
| Cecropin A TFA | Cecropin A is an antibacterial peptide that exists in a variety of organisms including mammals. It has a broad-spectrum antiparasitic and antibacterial activity. Grades: 98%. Molecular formula: C184H313N53O46.xC2HF3O2. Mole weight: 4003.78 (free base). | |
| Cecropin P1, porcine acetate | Cecropin P1, porcine acetate. | |
| Cediranib dihydrochloride | Cediranib (AZD-2171; tentative trade name Recentin) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.The drug is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration. Alternative Names: US brand name: Recentin. Foreign brand name: Recentin. Code name: AZD2171.AZD 2171; AZD-2171. CAS No. 288383-20-0. Molecular formula: C25H27FN4O3. Mole weight: 450.5. | |
| Cefaclor EP Impurity E | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Alternative Names: Cefaclor Open-Ring Impurity; 2-((R)-2-Amino-2-phenylacetamido)-2-(5-chloro-4-oxo-3,4-dihydro-2H-1,3-thiazin-2-yl)acetic Acid. Grades: 95%. CAS No. 188915-50-6. Molecular formula: C14H14ClN3O4S. Mole weight: 355.80. | |
| Cefazolin EP Impurity G | An impurity of Cefazolin, an antibiotic used for the treatment of bacterial infections. Alternative Names: Cefazolin Lactone; Cefazolin Sodium Impurity G. CAS No. 1172998-53-6. Molecular formula: C11H10N6O4S. Mole weight: 322.3. | |
| Cefazolin Impurity C | an impurity of Cefazolin. Alternative Names: (6R,7R)-3-Methyl-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid. Grades: > 95%. CAS No. 56842-77-4. Molecular formula: C11H12N6O4S. Mole weight: 324.32. | |
| Cefepime Related Compound E | An impurity of Cefepime. Cefepime is a fourth-generation cephalosporin antibiotic known for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria. It is particularly effective against many organisms that are resistant to other antibiotics, including some beta-lactamase-producing strains. Cefepime is often used to treat severe infections such as pneumonia, urinary tract infections, and bloodstream infections. Alternative Names: 1-{[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium chloride; 7-Amino-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride; Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride; Pyrrolidinium, 1-[(7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl]-1-methyl-, hydroxide, inner salt, monohydrochloride, (6R-trans)-; USP Cefepime Related Compound E; Cefepime USP Related Compound E; Cefepime amine derivative; (6R,7R)-7-Amino-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate chloride. Grades: ≥95%. CAS No. 103121-85-3. Molecular formula: C13H20ClN3O3S. Mole weight: 333.83. | |
| Cefixime EP Impurity D | Cefixime EP Impurity D is an impurity of cefixime which is a semi-synthetic third-generation oral cephalosporin antibiotic used to treat a variety of bacterial infections. Alternative Names: (E)-Cefixime; [6R-[6α,7β(E)]]-7-[[(2-Amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grades: 95%. CAS No. 97164-56-2. Molecular formula: C16H15N5O7S2. Mole weight: 453.45. | |
| Cefprozil Monohydrate EP Impurity C | Cefprozil Monohydrate EP Impurity C is an impurity of Cefprozil, which is a semisynthetic, broad-spectrum, second-generation cephalosporin with antibacterial activity. Alternative Names: Hydroxyphenyldiketopiperazine; (Z)-3-(aminomethylene)-6-(4-hydroxyphenyl)piperazine-2,5-dione. Grades: 90%. CAS No. 147103-93-3. Molecular formula: C11H11N3O3. Mole weight: 233.23. | |
| Cefprozil Monohydrate EP Impurity D | An impurity of Cefprozil, which is a cephalosporin antibiotic used to treat a variety of bacterial infections. Alternative Names: Cefprozil USP Related Compound D; 7-Amino-3-propenylcephalosporanic acid (Z-isomer). Grades: 90%. CAS No. 106447-44-3. Molecular formula: C10H12N2O3S. Mole weight: 240.28. | |
| Cefprozil Monohydrate EP Impurity G | An impurity of Cefprozil, a cephalosporin antibiotic used to treat a variety of bacterial infections. Alternative Names: Z-Cefprozil open ring (USP); (Z)-open ring cefprozil; (R)-2-{(R)-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido](carboxy)methyl}-5-[(Z)-prop-1-enyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid. Grades: 90%. Molecular formula: C18H21N3O6S. Mole weight: 407.44. | |
| Cefprozil Monohydrate EP Impurity I | An impurity of Cefprozil, a cephalosporin antibiotic used to treat a variety of bacterial infections. Alternative Names: E-Cefprozil open ring; (R)-2-{(R)-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido](carboxy)methyl}-5-[(E)-prop-1-enyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid. Grades: 90%. Molecular formula: C18H21N3O6S. Mole weight: 407.44. | |
| Cefprozil Monohydrate EP Impurity K | Cefprozil EP impurity K is an impurity of Cefprozil, which is a semisynthetic, broad-spectrum, second-generation cephalosporin with antibacterial activity. Alternative Names: Mixture of 4 diastereoisomers of (3RS,6RS)-3-[(2R,5R)-5-ethyl-7-oxo-1,2,5,7-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl]-6-(4-hydroxyphenyl)piperazine-2,5-dione. Grades: ≥95%. Molecular formula: C18H19N3O5S. Mole weight: 389.43. | |
| Ceftazidime Impurity H | An impurity of ceftazidime, an antibiotic used for certain infection treatment. Alternative Names: Methyl ceftazidime; Ceftazidime Methyl Ester. Grades: > 95%. CAS No. 1354396-23-8. Molecular formula: C23H24N6O7S2. Mole weight: 560.61. | |
| Ceftazidime Intermediate | An impurity of ceftazidime, an antibiotic used for certain infection treatment. Alternative Names: taem; (Z)-tert-Butyl 2-(((1-(2-aminothiazol-4-yl)-2-(benzo[d]thiazol-2-ylthio)-2-oxoethylidene)amino)oxy)-2-methylpropanoate. Grades: > 95%. CAS No. 158183-05-2. Molecular formula: C20H22N4O4S3. Mole weight: 478.61. | |
| Ceftibuten Dihydrate | Dihydrate form of Ceftibuten which is one of the third-generation cephalosporin antibiotics. Uses: Dihydrate form of ceftibuten which is one of the third-generation cephalosporin antibiotics. Alternative Names: ceftibuten dihydrate;(+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate;Sch-39720;(+)-(6R,7R)-7-[2-(2-Amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-az. Grades: 95%. CAS No. 118081-34-8. Molecular formula: C15H14N4O6S2.2(H2O). Mole weight: 446.45. | |
| Ceftizoxime TSM1 Impurity | Ceftizoxime TSM1 Impurity. CAS No. 929101-93-9. | |
| Cefuroxime Axetil Delta-3 | Δ2-Cefuroxime axetil is an oral prodrug of cefuroxime, a second-generation cephalosporin antibiotic. This compound inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins (PBPs), making it effective against a broad spectrum of Gram-positive and Gram-negative bacteria. It is commonly prescribed for respiratory, urinary tract, and skin infections. Alternative Names: 1-Acetoxyethyl (6R,7R)-3-((carbamoyloxy)methyl)-7-((Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate; 5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-; 5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, [6R-[6α,7β(Z)]]-; Cefuroxime Axetil Impurity A (Delta 3-Isomer); Cefuroxime Axetil EP Impurity A; Cefuroxime Axetil Impurity A (EP); Δ2-Cefuroxime axetil; delta3-Cefuroxime axetil. Grades: 95%. CAS No. 123458-61-7. Molecular formula: C20H22N4O10S. Mole weight: 510.47. | |
| Celecoxib Impurity 2 | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Alternative Names: 1H-Pyrazole, 5-(4-methylphenyl)-3-(trifluoromethyl)-; 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Methylphenyl)-3-trifluoromethyl-1H-pyrazole; Celecoxib Impurity H. Grades: > 95%. CAS No. 948293-46-7. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
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